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ONTOLOGY REPORT - ANNOTATIONS

Term:mRNA regulatory element binding translation repressor activity
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Accession:GO:0000900 term browser browse the term
Definition:Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid.
Synonyms:broad_synonym: translation repressor activity, nucleic acid binding
 xref: Reactome:R-HSA-5690886 "ACO1, IREB2 bind IREs in TFRC, ALAD, FTL, FTH1 mRNAs"

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mRNA regulatory element binding translation repressor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 enables ISO (PMID:1946430), (PMID:7983023), (PMID:8041788) Reactome PMID:1946430 PMID:7983023 PMID:8041788 NCBI chrNW_004624736:37,063,540...37,127,772
Ensembl chrNW_004624736:37,063,246...37,126,702 		JBrowse link
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624768:18,386,415...18,468,879 JBrowse link
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624755:16,732,561...16,791,108 JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624737:3,352,064...3,570,317
Ensembl chrNW_004624737:3,355,360...3,542,731 		JBrowse link
G Cpeb4 cytoplasmic polyadenylation element binding protein 4 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624733:16,082,461...16,146,798
Ensembl chrNW_004624733:16,082,369...16,147,075 		JBrowse link
G Dhfr dihydrofolate reductase enables ISO (PMID:8490020) CAFA PMID:8490020 NCBI chrNW_004624743:1,446,643...1,462,319
Ensembl chrNW_004624743:1,446,643...1,461,863 		JBrowse link
G Ireb2 iron responsive element binding protein 2 enables ISO (PMID:1946430), (PMID:7983023), (PMID:8041788) Reactome PMID:1946430 PMID:7983023 PMID:8041788 NCBI chrNW_004624894:2,446,014...2,498,650
Ensembl chrNW_004624894:2,445,704...2,499,009 		JBrowse link
G Paip2 poly(A) binding protein interacting protein 2 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624743:32,152,007...32,171,111 JBrowse link
G Paip2b poly(A) binding protein interacting protein 2B enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624762:2,335,522...2,379,674
Ensembl chrNW_004624762:2,335,544...2,375,376 		JBrowse link
G Pura purine rich element binding protein A enables ISO (PMID:12933792) HGNC-UCL PMID:12933792 NCBI chrNW_004624743:32,878,677...32,888,650
Ensembl chrNW_004624743:32,884,552...32,885,517 		JBrowse link
G Purb purine rich element binding protein B enables ISO PMID:12933792 HGNC-UCL PMID:12933792 RGD:1581942 NCBI chrNW_004624740:7,398,481...7,406,923
Ensembl chrNW_004624740:7,398,481...7,399,434 		JBrowse link
G Rara retinoic acid receptor alpha ISO RGD PMID:19073915 RGD:2314253 NCBI chrNW_004624795:2,935,432...2,975,226
Ensembl chrNW_004624795:2,934,731...2,967,232 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 enables ISO (PMID:10995219) CAFA PMID:10995219 NCBI chrNW_004624849:3,108,875...3,146,669
Ensembl chrNW_004624849:3,114,876...3,146,248 		JBrowse link
G Tyms thymidylate synthetase enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004624770:11,138,673...11,149,600
Ensembl chrNW_004624770:11,138,652...11,149,600 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18442
    translation regulator activity 190
      translation repressor activity 24
        mRNA regulatory element binding translation repressor activity 14
Path 2
Term Annotations click to browse term
  molecular_function 18442
    binding 16096
      nucleic acid binding 3877
        translation regulator activity, nucleic acid binding 170
          mRNA regulatory element binding translation repressor activity 14
paths to the root