Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:mRNA regulatory element binding translation repressor activity
go back to main search page
Accession:GO:0000900 term browser browse the term
Definition:Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid.
Synonyms:broad_synonym: translation repressor activity, nucleic acid binding
 xref: Reactome:R-HSA-5690886 "ACO1, IREB2 bind IREs in TFRC, ALAD, FTL, FTH1 mRNAs"


show annotations for term's descendants           Sort by:
mRNA regulatory element binding translation repressor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 enables ISO (PMID:1946430), (PMID:7983023), (PMID:8041788) Reactome PMID:1946430 PMID:7983023 PMID:8041788 NCBI chr 4:40,143,429...40,199,011
Ensembl chr 4:40,143,081...40,198,338 		JBrowse link
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 enables IDA
IBA		 (PMID:18752464) UniProt
GO_Central		 PMID:18752464 GO_REF:0000033 NCBI chr 7:80,996,774...81,105,207
Ensembl chr 7:80,996,774...81,105,213 		JBrowse link
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 enables IDA
ISO
ISS
IBA		 (PMID:18752464) UniProt
GO_Central		 PMID:18752464 GO_REF:0000024 GO_REF:0000033 GO_REF:0000096 NCBI chr 5:43,382,692...43,447,067
Ensembl chr 5:43,390,513...43,447,067 		JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 enables IDA
IBA		 (PMID:22157746) UniProt
GO_Central		 PMID:22157746 GO_REF:0000033 NCBI chr19:36,996,742...37,185,018
Ensembl chr19:36,998,691...37,186,000 		JBrowse link
G Cpeb4 cytoplasmic polyadenylation element binding protein 4 enables IBA GO_Central GO_REF:0000033 NCBI chr11:31,820,911...31,885,635
Ensembl chr11:31,822,211...31,885,634 		JBrowse link
G Dhfr dihydrofolate reductase enables ISO GO_Central GO_REF:0000119 NCBI chr13:92,491,291...92,525,561
Ensembl chr13:92,491,234...92,525,561 		JBrowse link
G Ireb2 iron responsive element binding protein 2 enables ISO (PMID:1946430), (PMID:7983023), (PMID:8041788) Reactome PMID:1946430 PMID:7983023 PMID:8041788 NCBI chr 9:54,769,942...54,819,812
Ensembl chr 9:54,771,073...54,819,814 		JBrowse link
G Paip2 polyadenylate-binding protein-interacting protein 2 enables ISO (PMID:16804161) MGI PMID:16804161 NCBI chr18:35,731,649...35,750,239
Ensembl chr18:35,731,670...35,750,240 		JBrowse link
G Paip2b poly(A) binding protein interacting protein 2B enables ISO
ISS		 (PMID:16804161) MGI
GO_Central
UniProt		 PMID:16804161 GO_REF:0000024 GO_REF:0000119 NCBI chr 6:83,783,040...83,808,723
Ensembl chr 6:83,782,383...83,808,723 		JBrowse link
G Pura purine rich element binding protein A enables IDA (PMID:12933792) HGNC-UCL PMID:12933792 NCBI chr18:36,413,614...36,434,575
Ensembl chr18:36,414,150...36,425,588 		JBrowse link
G Purb purine rich element binding protein B enables ISO GO_Central GO_REF:0000096 NCBI chr11:6,417,599...6,426,076
Ensembl chr11:6,417,599...6,425,917 		JBrowse link
G Rara retinoic acid receptor, alpha enables ISO
IEA		 RGD
GO_Central
Ensembl		 PMID:19073915 GO_REF:0000096 GO_REF:0000107 RGD:2314253 NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 (soluble) enables IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr11:60,679,723...60,702,062
Ensembl chr11:60,678,930...60,702,544 		JBrowse link
G Tyms thymidylate synthase enables IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 28796
    translation regulator activity 384
      translation repressor activity 271
        mRNA regulatory element binding translation repressor activity 14
Path 2
Term Annotations click to browse term
  molecular_function 28796
    binding 17614
      nucleic acid binding 3756
        translation regulator activity, nucleic acid binding 113
          mRNA regulatory element binding translation repressor activity 14
paths to the root