Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:mRNA regulatory element binding translation repressor activity
go back to main search page
Accession:GO:0000900 term browser browse the term
Definition:Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid.
Synonyms:broad_synonym: translation repressor activity, nucleic acid binding
 xref: Reactome:R-HSA-5690886 "ACO1, IREB2 bind IREs in TFRC, ALAD, FTL, FTH1 mRNAs"

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
mRNA regulatory element binding translation repressor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACO1 aconitase 1 enables ISO (PMID:1946430), (PMID:7983023), (PMID:8041788) Reactome PMID:1946430 PMID:7983023 PMID:8041788 NCBI chr12:47,771,140...47,874,478
Ensembl chr12:47,806,436...47,874,227 		JBrowse link
G CPEB1 cytoplasmic polyadenylation element binding protein 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr29:3,005,891...3,106,732
Ensembl chr29:3,006,532...3,106,793 		JBrowse link
G CPEB2 cytoplasmic polyadenylation element binding protein 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr27:35,143,510...35,209,851
Ensembl chr27:35,147,299...35,209,649 		JBrowse link
G CPEB3 cytoplasmic polyadenylation element binding protein 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 9:85,325,768...85,569,192
Ensembl chr 9:85,331,466...85,525,688 		JBrowse link
G CPEB4 cytoplasmic polyadenylation element binding protein 4 enables IEA TreeGrafter GO_REF:0000118 NCBI chr23:76,039,118...76,110,564
Ensembl chr23:76,040,516...76,106,360 		JBrowse link
G DHFR dihydrofolate reductase enables IEA Ensembl GO_REF:0000107 NCBI chr 4:74,787,292...74,811,196
Ensembl chr 4:74,787,629...74,810,960 		JBrowse link
G IREB2 iron responsive element binding protein 2 enables ISO (PMID:1946430), (PMID:7983023), (PMID:8041788) Reactome PMID:1946430 PMID:7983023 PMID:8041788 NCBI chr26:4,842,328...4,905,941
Ensembl chr26:4,842,122...4,905,964 		JBrowse link
G PAIP2 poly(A) binding protein interacting protein 2 enables IEA InterPro GO_REF:0000002 NCBI chr23:42,002,525...42,042,056
Ensembl chr23:42,002,482...42,042,777 		JBrowse link
G PAIP2B poly(A) binding protein interacting protein 2B enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr14:35,930,797...35,967,398
Ensembl chr14:35,930,819...35,972,073 		JBrowse link
G PURA purine rich element binding protein A enables IEA Ensembl GO_REF:0000107 NCBI chr23:42,757,963...42,767,393
Ensembl chr23:42,764,263...42,765,231 		JBrowse link
G PURB purine rich element binding protein B enables ISO PMID:12933792 HGNC-UCL PMID:12933792 RGD:1581942 NCBI chr21:13,796,087...13,805,162
Ensembl chr21:13,796,118...13,797,056 		JBrowse link
G RARA retinoic acid receptor alpha ISO RGD PMID:19073915 RGD:2314253 NCBI chr16:65,817,849...65,866,862
Ensembl chr16:65,817,757...65,866,878 		JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 enables ISO (PMID:10995219) CAFA PMID:10995219 NCBI chr16:17,371,704...17,408,499 JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 enables IEA Ensembl GO_REF:0000107 Ensembl chr16:17,373,039...17,408,663 JBrowse link
G TYMS thymidylate synthetase enables IEA Ensembl GO_REF:0000107 NCBI chr18:60,030,640...60,043,297
Ensembl chr18:60,030,658...60,041,856 		JBrowse link
G ZNF540 zinc finger protein 540 enables ISO (PMID:16815308) UniProt PMID:16815308 NCBI chr 6:32,272,552...32,292,480 JBrowse link
G ZNF540 zinc finger protein 540 enables IEA Ensembl GO_REF:0000107 Ensembl chr 6:32,279,823...32,294,609 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19845
    translation regulator activity 126
      translation repressor activity 28
        mRNA regulatory element binding translation repressor activity 17
Path 2
Term Annotations click to browse term
  molecular_function 19845
    binding 18023
      nucleic acid binding 4834
        translation regulator activity, nucleic acid binding 103
          mRNA regulatory element binding translation repressor activity 17
paths to the root