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ONTOLOGY REPORT - ANNOTATIONS

Term:synaptonemal complex
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Accession:GO:0000795 term browser browse the term
Definition:A proteinaceous scaffold found between homologous chromosomes during meiosis. It consists of 2 lateral elements and a central element, all running parallel to each other. Transverse filaments connect the lateral elements to the central element.
Synonyms:alt_id: GO:0005716
 xref: Wikipedia:Synaptonemal_complex
 never_in_taxon: NCBITaxon:4896 ! Schizosaccharomyces pombe

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synaptonemal complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnb1ip1 cyclin B1 interacting protein 1 located_in ISO (PMID:24390283) UniProt PMID:24390283 NCBI chrNW_004936877:523,022...528,387 JBrowse link
G Fkbp6 FKBP prolyl isomerase family member 6 (inactive) located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936543:2,638,189...2,646,589
Ensembl chrNW_004936543:2,638,016...2,646,589 		JBrowse link
G Hormad1 HORMA domain containing 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936580:933,123...956,201
Ensembl chrNW_004936580:933,365...954,486 		JBrowse link
G Hormad2 HORMA domain containing 2 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936904:477,398...546,574
Ensembl chrNW_004936904:477,398...546,574 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 located_in ISO (PMID:8622925) MGI PMID:8622925 NCBI chrNW_004936495:8,243,369...8,246,082 JBrowse link
G Incenp inner centromere protein located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936581:999,148...1,028,157
Ensembl chrNW_004936581:999,497...1,025,062 		JBrowse link
G Lig3 DNA ligase 3 located_in ISO (PMID:9001252) MGI PMID:9001252 NCBI chrNW_004936538:206,179...228,487
Ensembl chrNW_004936538:206,839...226,441 		JBrowse link
G LOC101955845 synaptonemal complex protein 3-like located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936809:42,732...53,271 JBrowse link
G LOC101977976 E3 ubiquitin-protein ligase CCNB1IP1 located_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936751:1,851,811...1,853,370 JBrowse link
G Mlh1 mutL homolog 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:26,556,636...26,600,830
Ensembl chrNW_004936473:26,556,611...26,603,736 		JBrowse link
G Mlh3 mutL homolog 3 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936488:4,164,322...4,195,408
Ensembl chrNW_004936488:4,164,918...4,195,517 		JBrowse link
G Msh4 mutS homolog 4 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936571:2,827,283...2,898,562
Ensembl chrNW_004936571:2,822,058...2,898,562 		JBrowse link
G Msh5 mutS homolog 5 located_in ISO (PMID:16260499) MGI PMID:16260499 NCBI chrNW_004936727:1,776,038...1,794,152
Ensembl chrNW_004936727:1,777,570...1,793,711 		JBrowse link
G P3h4 prolyl 3-hydroxylase family member 4 (inactive) ISO RGD PMID:1363622 RGD:633987 NCBI chrNW_004936490:16,705,716...16,712,324
Ensembl chrNW_004936490:16,705,690...16,712,324 		JBrowse link
G Plk1 polo like kinase 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:8,321,415...8,332,414
Ensembl chrNW_004936501:8,321,305...8,332,424 		JBrowse link
G Rec8 REC8 meiotic recombination protein located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936722:369,366...375,243
Ensembl chrNW_004936722:369,423...375,243 		JBrowse link
G Rnf212 ring finger protein 212 located_in ISO (PMID:23396135), (PMID:24390283) UniProt PMID:23396135 PMID:24390283 NCBI chrNW_004936477:22,122,854...22,173,324 JBrowse link
G Rnf212b ring finger protein 212B located_in IEA TreeGrafter
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936722:1,086,237...1,116,352
Ensembl chrNW_004936722:1,088,424...1,116,352 		JBrowse link
G Smc1a structural maintenance of chromosomes 1A ISO MMO:0000679 RGD PMID:10652260 RGD:1331378 NCBI chrNW_004936751:332,351...388,756
Ensembl chrNW_004936751:349,597...388,755 		JBrowse link
G Smc1b structural maintenance of chromosomes 1B located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936629:4,315,401...4,389,318
Ensembl chrNW_004936629:4,315,401...4,389,069 		JBrowse link
G Smc3 structural maintenance of chromosomes 3 ISO MMO:0000679 RGD PMID:10652260 RGD:1331378 NCBI chrNW_004936486:1,409,757...1,436,206
Ensembl chrNW_004936486:1,408,045...1,435,875 		JBrowse link
G Stag3 STAG3 cohesin complex component located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936543:430,804...458,112
Ensembl chrNW_004936543:432,552...458,112 		JBrowse link
G Syce1 synaptonemal complex central element protein 1 located_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936486:19,723,354...19,731,175
Ensembl chrNW_004936486:19,723,627...19,727,770 		JBrowse link
G Sycp1 synaptonemal complex protein 1 located_in ISO (PMID:12815066), (PMID:16968740), (PMID:17696610), (PMID:18070917), (PMID:18316482), (PMID:20551173), (PMID:22011390), (PMID:25675407), (PMID:26358182), (PMID:26490168), (PMID:27473657), (PMID:27760146), (PMID:27856912), (PMID:30718482)
(PMID:15937223)		 RGD
MGI
UniProt		 PMID:8660935 PMID:12815066 PMID:15937223 PMID:16968740 PMID:17696610 More... RGD:8554354 RGD:9686370 NCBI chrNW_004936627:239,232...365,062 JBrowse link
G Sycp2 synaptonemal complex protein 2 located_in ISO (PMID:18316482), (PMID:26362258) RGD
MGI		 PMID:9592139 PMID:18316482 PMID:26362258 RGD:69387 NCBI chrNW_004936514:8,264,628...8,331,577 JBrowse link
G Sycp3 synaptonemal complex protein 3 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936492:12,316,868...12,326,778
Ensembl chrNW_004936492:12,316,869...12,330,251 		JBrowse link
G Syn1 synapsin I located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936502:13,334,998...13,387,082
Ensembl chrNW_004936502:13,334,995...13,387,172 		JBrowse link
G Tex11 testis expressed 11 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936762:681,962...969,749
Ensembl chrNW_004936762:681,130...969,455 		JBrowse link
G Tex12 testis expressed 12 located_in ISO (PMID:16968740) MGI PMID:16968740 NCBI chrNW_004936612:2,297,754...2,303,130 JBrowse link
central element term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CUNH14orf39 chromosome unknown C14orf39 homolog located_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936495:4,660,616...4,695,338
Ensembl chrNW_004936495:4,660,641...4,694,402 		JBrowse link
G Incenp inner centromere protein located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936581:999,148...1,028,157
Ensembl chrNW_004936581:999,497...1,025,062 		JBrowse link
G Syce1 synaptonemal complex central element protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936486:19,723,354...19,731,175
Ensembl chrNW_004936486:19,723,627...19,727,770 		JBrowse link
G Syce2 synaptonemal complex central element protein 2 located_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004936659:1,962,055...1,978,743
Ensembl chrNW_004936659:1,961,243...1,978,743 		JBrowse link
G Syce3 synaptonemal complex central element protein 3 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936629:264,077...281,119
Ensembl chrNW_004936629:264,077...281,119 		JBrowse link
G Sycp1 synaptonemal complex protein 1 located_in ISO (PMID:12584241), (PMID:23133398) MGI PMID:12584241 PMID:23133398 NCBI chrNW_004936627:239,232...365,062 JBrowse link
G Tex11 testis expressed 11 located_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936762:681,962...969,749
Ensembl chrNW_004936762:681,130...969,455 		JBrowse link
G Tex12 testis expressed 12 located_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936612:2,297,754...2,303,130 JBrowse link
lateral element term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:16,194,092...16,295,803
Ensembl chrNW_004936483:16,194,092...16,255,905 		JBrowse link
G Brca1 BRCA1 DNA repair associated located_in ISO (PMID:9774970) MGI PMID:9774970 NCBI chrNW_004936490:17,735,444...17,801,456 JBrowse link
G Brca2 BRCA2 DNA repair associated located_in ISO (PMID:9774970) MGI PMID:9774970 NCBI chrNW_004936472:26,945,659...27,017,693 JBrowse link
G Dmc1 DNA meiotic recombinase 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:2,754,694...2,788,249
Ensembl chrNW_004936492:2,753,289...2,788,102 		JBrowse link
G Incenp inner centromere protein located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936581:999,148...1,028,157
Ensembl chrNW_004936581:999,497...1,025,062 		JBrowse link
G Kash5 KASH domain containing 5 located_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936664:3,268,824...3,300,689
Ensembl chrNW_004936664:3,275,669...3,297,605 		JBrowse link
G Mei4 meiotic double-stranded break formation protein 4 located_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936510:12,063,763...12,208,789
Ensembl chrNW_004936510:12,063,763...12,208,799 		JBrowse link
G Rad21l1 RAD21 cohesin complex component like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:17,413,006...17,435,951
Ensembl chrNW_004936485:17,413,006...17,435,951 		JBrowse link
G Rad51 RAD51 recombinase located_in ISO (PMID:9774970)
(PMID:18694567), (PMID:21743440)		 MGI PMID:9774970 PMID:18694567 PMID:21743440 NCBI chrNW_004936471:4,119,020...4,136,811
Ensembl chrNW_004936471:4,114,530...4,136,248 		JBrowse link
G Rec8 REC8 meiotic recombination protein located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936722:369,366...375,243
Ensembl chrNW_004936722:369,423...375,243 		JBrowse link
G Rpa1 replication protein A1 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:7,941,074...7,997,062
Ensembl chrNW_004936538:7,946,403...7,994,864 		JBrowse link
G Smc1a structural maintenance of chromosomes 1A ISO MMO:0000662 RGD PMID:10652260 RGD:1331378 NCBI chrNW_004936751:332,351...388,756
Ensembl chrNW_004936751:349,597...388,755 		JBrowse link
G Smc1b structural maintenance of chromosomes 1B located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936629:4,315,401...4,389,318
Ensembl chrNW_004936629:4,315,401...4,389,069 		JBrowse link
G Smc3 structural maintenance of chromosomes 3 located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936486:1,409,757...1,436,206
Ensembl chrNW_004936486:1,408,045...1,435,875 		JBrowse link
G Stag3 STAG3 cohesin complex component located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936543:430,804...458,112
Ensembl chrNW_004936543:432,552...458,112 		JBrowse link
G Sycp2 synaptonemal complex protein 2 located_in ISO PMID:9933407
(PMID:18283110), (PMID:22011390), (PMID:22711701), (PMID:23133398)		 UniProt
MGI		 PMID:9933407 PMID:18283110 PMID:22011390 PMID:22711701 PMID:23133398 RGD:11035335 NCBI chrNW_004936514:8,264,628...8,331,577 JBrowse link
G Sycp2l synaptonemal complex protein 2 like located_in ISO (PMID:26362258) MGI PMID:26362258 NCBI chrNW_004936534:2,024,341...2,131,241 JBrowse link
G Sycp3 synaptonemal complex protein 3 located_in ISO PMID:9933407
(PMID:10678170), (PMID:18802469), (PMID:19283064), (PMID:21539824), (PMID:21743440), (PMID:22011390), (PMID:22711701), (PMID:22854038), (PMID:23133398), (PMID:23555294), (PMID:25533956), (PMID:25675407)		 UniProt
MGI		 PMID:9933407 PMID:10678170 PMID:18802469 PMID:19283064 PMID:21539824 More... RGD:11035335 NCBI chrNW_004936492:12,316,868...12,326,778
Ensembl chrNW_004936492:12,316,869...12,330,251 		JBrowse link
transverse filament term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stag3 STAG3 cohesin complex component located_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936543:430,804...458,112
Ensembl chrNW_004936543:432,552...458,112 		JBrowse link
G Sycp1 synaptonemal complex protein 1 located_in ISO (PMID:15870106), (PMID:18283110), (PMID:21539824), (PMID:22711701) RGD
MGI		 PMID:1464329 PMID:15870106 PMID:18283110 PMID:21539824 PMID:22711701 RGD:729937 NCBI chrNW_004936627:239,232...365,062 JBrowse link
G Sycp3 synaptonemal complex protein 3 located_in ISO (PMID:15870106) MGI PMID:15870106 NCBI chrNW_004936492:12,316,868...12,326,778
Ensembl chrNW_004936492:12,316,869...12,330,251 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18229
    cellular anatomical structure 18007
      synaptonemal structure 42
        synaptonemal complex 42
          central element 8
          lateral element 18
          transverse filament 3
Path 2
Term Annotations click to browse term
  cellular_component 18229
    cellular anatomical structure 18007
      organelle 13374
        intracellular organelle 12970
          intracellular membrane-bounded organelle 11794
            nucleus 7736
              nuclear lumen 4139
                nuclear chromosome 218
                  condensed nuclear chromosome 82
                    synaptonemal structure 42
                      synaptonemal complex 42
                        central element 8
                        lateral element 18
                        transverse filament 3
paths to the root