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ONTOLOGY REPORT - ANNOTATIONS

Term:synaptonemal complex
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Accession:GO:0000795 term browser browse the term
Definition:A proteinaceous scaffold found between homologous chromosomes during meiosis. It consists of 2 lateral elements and a central element, all running parallel to each other. Transverse filaments connect the lateral elements to the central element.
Synonyms:alt_id: GO:0005716
 xref: Wikipedia:Synaptonemal_complex
 never_in_taxon: NCBITaxon:4896 ! Schizosaccharomyces pombe


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synaptonemal complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNB1IP1 cyclin B1 interacting protein 1 located_in IEA
ISS		 InterPro
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr14:20,311,370...20,333,279
Ensembl chr14:20,311,368...20,333,312 		JBrowse link
G FAM9A family with sequence similarity 9 member A is_active_in IBA GO_Central GO_REF:0000033 NCBI chr  X:8,790,795...8,801,383
Ensembl chr  X:8,790,795...8,801,383 		JBrowse link
G FAM9B family with sequence similarity 9 member B is_active_in IBA GO_Central GO_REF:0000033 NCBI chr  X:9,024,232...9,034,127
Ensembl chr  X:9,024,232...9,295,682 		JBrowse link
G FAM9C family with sequence similarity 9 member C is_active_in IBA GO_Central GO_REF:0000033 NCBI chr  X:13,035,617...13,044,620
Ensembl chr  X:13,035,617...13,044,682 		JBrowse link
G FKBP6 FKBP prolyl isomerase family member 6 (inactive) located_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:73,328,161...73,358,625
Ensembl chr 7:73,328,161...73,358,637 		JBrowse link
G HORMAD1 HORMA domain containing 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:150,698,060...150,720,895
Ensembl chr 1:150,698,060...150,720,895 		JBrowse link
G HORMAD2 HORMA domain containing 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr22:30,077,732...30,207,456
Ensembl chr22:30,080,464...30,177,075 		JBrowse link
G HSPA2 heat shock protein family A (Hsp70) member 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr14:64,535,905...64,543,237
Ensembl chr14:64,535,905...64,546,173 		JBrowse link
G INCENP inner centromere protein located_in IEA Ensembl GO_REF:0000107 NCBI chr11:62,124,011...62,153,169
Ensembl chr11:62,123,998...62,155,474 		JBrowse link
G LIG3 DNA ligase 3 located_in ISO (PMID:9001252) MGI PMID:9001252 NCBI chr17:34,980,512...35,010,872
Ensembl chr17:34,980,512...35,009,743 		JBrowse link
G MLH1 mutL homolog 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:36,993,466...37,050,846
Ensembl chr 3:36,993,226...37,050,896 		JBrowse link
G MLH3 mutL homolog 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr14:75,013,775...75,051,467
Ensembl chr14:75,013,769...75,051,532 		JBrowse link
G MSH4 mutS homolog 4 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:75,796,882...75,913,242
Ensembl chr 1:75,796,882...75,913,242 		JBrowse link
G MSH5 mutS homolog 5 located_in ISO (PMID:16260499) MGI PMID:16260499 NCBI chr 6:31,740,005...31,762,676
Ensembl chr 6:31,739,677...31,762,676 		JBrowse link
G P3H4 prolyl 3-hydroxylase family member 4 (inactive) located_in ISO
TAS		 (PMID:8862517) RGD
PINC		 PMID:1363622 PMID:8862517 RGD:633987 NCBI chr17:41,801,953...41,811,949
Ensembl chr17:41,801,947...41,812,604 		JBrowse link
G PLK1 polo like kinase 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,678,889...23,690,367
Ensembl chr16:23,677,656...23,690,367 		JBrowse link
G REC8 REC8 meiotic recombination protein located_in IEA Ensembl GO_REF:0000107 NCBI chr14:24,172,080...24,180,923
Ensembl chr14:24,171,853...24,180,257 		JBrowse link
G RNF212 ring finger protein 212 located_in
is_active_in		 IEA
IBA
ISS		 InterPro
GO_Central
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:1,056,251...1,113,710
Ensembl chr 4:1,056,250...1,113,564 		JBrowse link
G RNF212B ring finger protein 212B located_in
is_active_in		 IEA
IBA
ISS		 InterPro
GO_Central
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr14:23,185,336...23,273,477
Ensembl chr14:23,185,316...23,273,477 		JBrowse link
G SMC1A structural maintenance of chromosomes 1A ISO MMO:0000679 RGD PMID:10652260 RGD:1331378 NCBI chr  X:53,374,149...53,422,728
Ensembl chr  X:53,374,149...53,422,728 		JBrowse link
G SMC1B structural maintenance of chromosomes 1B located_in IEA Ensembl GO_REF:0000107 NCBI chr22:45,344,063...45,413,599
Ensembl chr22:45,344,063...45,413,619 		JBrowse link
G SMC3 structural maintenance of chromosomes 3 ISO MMO:0000679 RGD PMID:10652260 RGD:1331378 NCBI chr10:110,567,695...110,606,048
Ensembl chr10:110,567,684...110,606,048 		JBrowse link
G STAG3 STAG3 cohesin complex component located_in TAS
IEA		 (PMID:10698974) PINC
Ensembl		 PMID:10698974 GO_REF:0000107 NCBI chr 7:100,177,724...100,219,334
Ensembl chr 7:100,177,563...100,214,387 		JBrowse link
G SYCE1 synaptonemal complex central element protein 1 located_in
is_active_in		 IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:133,553,899...133,568,291
Ensembl chr10:133,553,901...133,569,835 		JBrowse link
G SYCE1L synaptonemal complex central element protein 1 like located_in
is_active_in		 IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr16:77,199,408...77,213,215
Ensembl chr16:77,199,408...77,213,215 		JBrowse link
G SYCP1 synaptonemal complex protein 1 located_in ISO
ISS
IEA		 RGD
UniProt
Ensembl
InterPro		 PMID:8660935 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 RGD:9686370 NCBI chr 1:114,854,088...114,995,370
Ensembl chr 1:114,854,863...114,995,370 		JBrowse link
G SYCP2 synaptonemal complex protein 2 located_in ISO
IEA
NAS		 (PMID:10341103) RGD
Ensembl
UniProt		 PMID:9592139 PMID:10341103 GO_REF:0000107 RGD:69387 NCBI chr20:59,863,571...59,933,637
Ensembl chr20:59,863,564...59,933,655 		JBrowse link
G SYCP3 synaptonemal complex protein 3 located_in
is_active_in		 IDA
IBA		 (PMID:9774970) MGI
GO_Central		 PMID:9774970 GO_REF:0000033 NCBI chr12:101,728,648...101,739,462
Ensembl chr12:101,728,648...101,739,472 		JBrowse link
G SYN1 synapsin I located_in IEA Ensembl GO_REF:0000107 NCBI chr  X:47,571,901...47,619,857
Ensembl chr  X:47,571,901...47,619,857 		JBrowse link
G TEX11 testis expressed 11 located_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:70,511,227...70,908,711
Ensembl chr  X:70,528,940...70,908,711 		JBrowse link
G TEX12 testis expressed 12 located_in IEA Ensembl GO_REF:0000107 NCBI chr11:112,167,372...112,172,556
Ensembl chr11:112,167,372...112,172,556 		JBrowse link
G UBE2I ubiquitin conjugating enzyme E2 I located_in TAS (PMID:8610150) PINC PMID:8610150 NCBI chr16:1,309,152...1,327,017
Ensembl chr16:1,291,444...1,327,018 		JBrowse link
central element term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C14orf39 chromosome 14 open reading frame 39 located_in
is_active_in		 ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr14:60,435,956...60,515,544
Ensembl chr14:60,396,469...60,515,543 		JBrowse link
G INCENP inner centromere protein located_in IEA Ensembl GO_REF:0000107 NCBI chr11:62,124,011...62,153,169
Ensembl chr11:62,123,998...62,155,474 		JBrowse link
G SYCE1 synaptonemal complex central element protein 1 located_in IEA
ISS		 (PMID:15944401) Ensembl
HGNC-UCL		 PMID:15944401 GO_REF:0000107 NCBI chr10:133,553,899...133,568,291
Ensembl chr10:133,553,901...133,569,835 		JBrowse link
G SYCE2 synaptonemal complex central element protein 2 located_in
is_active_in		 ISS
IBA
IEA		 HGNC
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr19:12,898,786...12,919,293
Ensembl chr19:12,898,786...12,919,293 		JBrowse link
G SYCE3 synaptonemal complex central element protein 3 located_in
is_active_in		 IEA
IBA
ISS		 Ensembl
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr22:50,551,112...50,562,919
Ensembl chr22:50,551,112...50,562,919 		JBrowse link
G SYCP1 synaptonemal complex protein 1 located_in
is_active_in		 IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:114,854,088...114,995,370
Ensembl chr 1:114,854,863...114,995,370 		JBrowse link
G TEX11 testis expressed 11 located_in
is_active_in		 IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:70,511,227...70,908,711
Ensembl chr  X:70,528,940...70,908,711 		JBrowse link
G TEX12 testis expressed 12 located_in
is_active_in		 ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr11:112,167,372...112,172,556
Ensembl chr11:112,167,372...112,172,556 		JBrowse link
lateral element term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLM BLM RecQ like helicase located_in IDA (PMID:10728666) UniProt PMID:10728666 NCBI chr15:90,717,346...90,816,166
Ensembl chr15:90,717,346...90,816,166 		JBrowse link
G BRCA1 BRCA1 DNA repair associated located_in IDA (PMID:9774970) MGI PMID:9774970 NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245 		JBrowse link
G BRCA2 BRCA2 DNA repair associated located_in IDA (PMID:9774970) MGI PMID:9774970 NCBI chr13:32,315,077...32,400,268
Ensembl chr13:32,315,086...32,400,268 		JBrowse link
G DMC1 DNA meiotic recombinase 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr22:38,509,147...38,570,183
Ensembl chr22:38,518,948...38,570,204 		JBrowse link
G INCENP inner centromere protein located_in IEA Ensembl GO_REF:0000107 NCBI chr11:62,124,011...62,153,169
Ensembl chr11:62,123,998...62,155,474 		JBrowse link
G KASH5 KASH domain containing 5 located_in
is_active_in		 IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr19:49,388,249...49,417,990
Ensembl chr19:49,388,219...49,417,990 		JBrowse link
G MEI4 meiotic double-stranded break formation protein 4 located_in
is_active_in		 ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:77,650,274...77,927,045
Ensembl chr 6:77,650,274...77,927,045 		JBrowse link
G RAD21L1 RAD21 cohesin complex component like 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr20:1,226,044...1,255,876
Ensembl chr20:1,226,044...1,296,421 		JBrowse link
G RAD51 RAD51 recombinase located_in IEA
IDA		 (PMID:9774970) Ensembl
MGI		 PMID:9774970 GO_REF:0000107 NCBI chr15:40,694,733...40,732,340
Ensembl chr15:40,694,774...40,732,340 		JBrowse link
G REC8 REC8 meiotic recombination protein located_in IEA Ensembl GO_REF:0000107 NCBI chr14:24,172,080...24,180,923
Ensembl chr14:24,171,853...24,180,257 		JBrowse link
G RPA1 replication protein A1 located_in ISO (PMID:21743440), (PMID:22711701) MGI PMID:21743440 PMID:22711701 NCBI chr17:1,830,005...1,900,082
Ensembl chr17:1,829,702...1,900,082 		JBrowse link
G SMC1A structural maintenance of chromosomes 1A ISO MMO:0000662 RGD PMID:10652260 RGD:1331378 NCBI chr  X:53,374,149...53,422,728
Ensembl chr  X:53,374,149...53,422,728 		JBrowse link
G SMC1B structural maintenance of chromosomes 1B located_in IEA Ensembl GO_REF:0000107 NCBI chr22:45,344,063...45,413,599
Ensembl chr22:45,344,063...45,413,619 		JBrowse link
G SMC3 structural maintenance of chromosomes 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr10:110,567,695...110,606,048
Ensembl chr10:110,567,684...110,606,048 		JBrowse link
G STAG3 STAG3 cohesin complex component located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:100,177,724...100,219,334
Ensembl chr 7:100,177,563...100,214,387 		JBrowse link
G SYCP2 synaptonemal complex protein 2 located_in
is_active_in		 ISS
IBA
IEA		 UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:59,863,571...59,933,637
Ensembl chr20:59,863,564...59,933,655 		JBrowse link
G SYCP2L synaptonemal complex protein 2 like is_active_in
located_in		 IBA
ISO		 (PMID:26362258) GO_Central
MGI		 PMID:26362258 GO_REF:0000033 NCBI chr 6:10,887,052...10,974,309
Ensembl chr 6:10,886,831...10,979,320 		JBrowse link
G SYCP3 synaptonemal complex protein 3 located_in ISS UniProt GO_REF:0000024 NCBI chr12:101,728,648...101,739,462
Ensembl chr12:101,728,648...101,739,472 		JBrowse link
transverse filament term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STAG3 STAG3 cohesin complex component located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:100,177,724...100,219,334
Ensembl chr 7:100,177,563...100,214,387 		JBrowse link
G SYCP1 synaptonemal complex protein 1 located_in
is_active_in		 ISO
IEA
IBA		 RGD
Ensembl
GO_Central		 PMID:1464329 GO_REF:0000033 GO_REF:0000107 RGD:729937 NCBI chr 1:114,854,088...114,995,370
Ensembl chr 1:114,854,863...114,995,370 		JBrowse link
G SYCP3 synaptonemal complex protein 3 located_in ISO (PMID:15870106) MGI PMID:15870106 NCBI chr12:101,728,648...101,739,462
Ensembl chr12:101,728,648...101,739,472 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21533
    cellular anatomical structure 21182
      synaptonemal structure 45
        synaptonemal complex 45
          central element 8
          lateral element 18
          transverse filament 3
Path 2
Term Annotations click to browse term
  cellular_component 21533
    cellular anatomical structure 21182
      organelle 16330
        intracellular organelle 15360
          intracellular membrane-bounded organelle 14188
            nucleus 9354
              nuclear lumen 5752
                nuclear chromosome 252
                  condensed nuclear chromosome 89
                    synaptonemal structure 45
                      synaptonemal complex 45
                        central element 8
                        lateral element 18
                        transverse filament 3
paths to the root