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ONTOLOGY REPORT - ANNOTATIONS

Term:synaptonemal complex
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Accession:GO:0000795 term browser browse the term
Definition:A proteinaceous scaffold found between homologous chromosomes during meiosis. It consists of 2 lateral elements and a central element, all running parallel to each other. Transverse filaments connect the lateral elements to the central element.
Synonyms:alt_id: GO:0005716
 xref: Wikipedia:Synaptonemal_complex
 never_in_taxon: NCBITaxon:4896 ! Schizosaccharomyces pombe

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synaptonemal complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnb1ip1 cyclin B1 interacting protein 1 located_in ISO (PMID:24390283) UniProt PMID:24390283 NCBI chrNW_004955550:1,108,764...1,138,862
Ensembl chrNW_004955550:1,108,449...1,138,862 		JBrowse link
G Fkbp6 FKBP prolyl isomerase family member 6 (inactive) located_in ISO (PMID:12764197) UniProt PMID:12764197 NCBI chrNW_004955456:14,291,445...14,318,310
Ensembl chrNW_004955456:14,291,260...14,318,310 		JBrowse link
G Hormad1 HORMA domain containing 1 located_in ISO (PMID:22854038) MGI PMID:22854038 NCBI chrNW_004955413:130,214...155,381
Ensembl chrNW_004955413:132,711...152,720 		JBrowse link
G Hormad2 HORMA domain containing 2 located_in ISO (PMID:22854038) MGI PMID:22854038 NCBI chrNW_004955455:4,309,397...4,462,932
Ensembl chrNW_004955455:4,317,319...4,424,645 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 located_in ISO (PMID:8622925) MGI PMID:8622925 NCBI chrNW_004955466:5,344,366...5,347,707
Ensembl chrNW_004955466:5,344,366...5,347,707 		JBrowse link
G Incenp inner centromere protein located_in ISO (PMID:12584241) MGI PMID:12584241 NCBI chrNW_004955511:5,705,948...5,724,167
Ensembl chrNW_004955511:5,706,201...5,720,772 		JBrowse link
G Lig3 DNA ligase 3 located_in ISO (PMID:9001252) MGI PMID:9001252 NCBI chrNW_004955481:9,696,050...9,716,154
Ensembl chrNW_004955481:9,696,054...9,715,637 		JBrowse link
G Mlh1 mutL homolog 1 located_in ISO PMID:16968740
(PMID:15467367), (PMID:16260499)		 MGI PMID:15467367 PMID:16260499 PMID:16968740 RGD:8554354 NCBI chrNW_004955421:3,890,291...3,936,892
Ensembl chrNW_004955421:3,890,306...3,936,526 		JBrowse link
G Mlh3 mutL homolog 3 located_in ISO (PMID:15467367), (PMID:16260499) MGI PMID:15467367 PMID:16260499 NCBI chrNW_004955523:515,409...547,257
Ensembl chrNW_004955523:518,565...546,410 		JBrowse link
G Msh4 mutS homolog 4 located_in ISO (PMID:10809667), (PMID:16260499) MGI PMID:10809667 PMID:16260499 NCBI chrNW_004955423:17,093,573...17,154,910
Ensembl chrNW_004955423:17,093,573...17,154,910 		JBrowse link
G Msh5 mutS homolog 5 located_in ISO (PMID:16260499) MGI PMID:16260499 NCBI chrNW_004955437:275,976...297,268
Ensembl chrNW_004955437:279,744...297,153 		JBrowse link
G P3h4 prolyl 3-hydroxylase family member 4 (inactive) ISO RGD PMID:1363622 RGD:633987 NCBI chrNW_004955451:16,020,101...16,024,063
Ensembl chrNW_004955451:16,020,101...16,024,084 		JBrowse link
G Plk1 polo like kinase 1 located_in ISO (PMID:22854038) MGI PMID:22854038 NCBI chrNW_004955493:2,206,353...2,217,231
Ensembl chrNW_004955493:2,206,353...2,217,231 		JBrowse link
G Rec8 REC8 meiotic recombination protein located_in ISO (PMID:12759374) MGI PMID:12759374 NCBI chrNW_004955409:36,223,783...36,231,749
Ensembl chrNW_004955409:36,223,844...36,230,948 		JBrowse link
G Rnf212 ring finger protein 212 located_in ISO (PMID:23396135), (PMID:24390283) UniProt PMID:23396135 PMID:24390283 NCBI chrNW_004955514:525,430...559,037
Ensembl chrNW_004955514:525,085...559,153 		JBrowse link
G Rnf212b ring finger protein 212B located_in ISO (PMID:38865271) UniProt PMID:38865271 NCBI chrNW_004955409:37,041,751...37,095,179 JBrowse link
G Smc1a structural maintenance of chromosomes 1A ISO MMO:0000679 RGD PMID:10652260 RGD:1331378 NCBI chrNW_004955475:421,472...468,286
Ensembl chrNW_004955475:421,409...468,324 		JBrowse link
G Smc1b structural maintenance of chromosomes 1B located_in ISO (PMID:11564881), (PMID:16968740) MGI PMID:11564881 PMID:16968740 NCBI chrNW_004955413:29,709,473...29,765,043
Ensembl chrNW_004955413:29,709,473...29,765,043 		JBrowse link
G Smc3 structural maintenance of chromosomes 3 ISO MMO:0000679 RGD PMID:10652260 RGD:1331378 NCBI chrNW_004955485:815,281...848,561 JBrowse link
G Stag3 STAG3 cohesin complex component located_in ISO (PMID:10698974) MGI PMID:10698974 NCBI chrNW_004955573:602,635...631,775
Ensembl chrNW_004955573:602,016...630,936 		JBrowse link
G Syce1 synaptonemal complex central element protein 1 located_in ISO PMID:16968740 MGI PMID:16968740 RGD:8554354 NCBI chrNW_004955507:6,263,070...6,271,289
Ensembl chrNW_004955507:6,264,059...6,271,729 		JBrowse link
G Sycp1 synaptonemal complex protein 1 located_in ISO (PMID:15937223)
PMID:16968740
(PMID:12815066), (PMID:16968740), (PMID:17696610), (PMID:18070917), (PMID:18316482), (PMID:20551173), (PMID:22011390), (PMID:25675407), (PMID:26358182), (PMID:26490168), (PMID:27473657), (PMID:27760146), (PMID:27856912), (PMID:30718482)		 RGD
UniProt
MGI		 PMID:8660935 PMID:12815066 PMID:15937223 PMID:16968740 PMID:17696610 More... RGD:8554354 RGD:9686370 NCBI chrNW_004955435:18,157,173...18,291,732 JBrowse link
G Sycp2 synaptonemal complex protein 2 located_in ISO (PMID:18316482), (PMID:26362258) RGD
MGI		 PMID:9592139 PMID:18316482 PMID:26362258 RGD:69387 NCBI chrNW_004955528:3,809,438...3,887,055
Ensembl chrNW_004955528:3,809,438...3,886,312 		JBrowse link
G Sycp3 synaptonemal complex protein 3 located_in ISO (PMID:9774970)
(PMID:12815066), (PMID:14736746), (PMID:15657431), (PMID:16428451), (PMID:16968740), (PMID:17141210), (PMID:17696610), (PMID:17912366), (PMID:18070917), (PMID:20551173), (PMID:22854038), (PMID:23810942), (PMID:26358182), (PMID:26490168), (PMID:27473657), (PMID:27760146), (PMID:27856912), (PMID:30718482), (PMID:31839538)		 MGI PMID:9774970 PMID:12815066 PMID:14736746 PMID:15657431 PMID:16428451 More... NCBI chrNW_004955405:37,093,330...37,102,789
Ensembl chrNW_004955405:37,093,652...37,102,856 		JBrowse link
G Syn1 synapsin I located_in ISO (PMID:14736746) MGI PMID:14736746 NCBI chrNW_004955516:460,258...521,484
Ensembl chrNW_004955516:460,198...521,484 		JBrowse link
G Tex11 testis expressed 11 located_in ISO (PMID:18369460) UniProt PMID:18369460 NCBI chrNW_004955475:10,057,708...10,432,087 JBrowse link
G Tex12 testis expressed 12 located_in ISO (PMID:16968740) MGI PMID:16968740 NCBI chrNW_004955412:13,829,637...13,834,481
Ensembl chrNW_004955412:13,831,353...13,834,481 		JBrowse link
central element term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CUNH14orf39 chromosome unknown C14orf39 homolog located_in ISO (PMID:27796301) UniProt PMID:27796301 NCBI chrNW_004955466:9,158,022...9,194,088
Ensembl chrNW_004955466:9,157,944...9,195,226 		JBrowse link
G Incenp inner centromere protein located_in ISO (PMID:12584241) MGI PMID:12584241 NCBI chrNW_004955511:5,705,948...5,724,167
Ensembl chrNW_004955511:5,706,201...5,720,772 		JBrowse link
G Syce1 synaptonemal complex central element protein 1 located_in ISO (PMID:15944401), (PMID:22164254) HGNC-UCL PMID:15944401 PMID:22164254 NCBI chrNW_004955507:6,263,070...6,271,289
Ensembl chrNW_004955507:6,264,059...6,271,729 		JBrowse link
G Syce2 synaptonemal complex central element protein 2 located_in ISO (PMID:15944401), (PMID:22164254), (PMID:22854038) MGI PMID:15944401 PMID:22164254 PMID:22854038 NCBI chrNW_004955415:31,957,244...31,969,922
Ensembl chrNW_004955415:31,957,489...31,969,859 		JBrowse link
G Syce3 synaptonemal complex central element protein 3 located_in ISO (PMID:21637789), (PMID:22164254) UniProt PMID:21637789 PMID:22164254 NCBI chrNW_004955413:33,537,646...33,573,787
Ensembl chrNW_004955413:33,537,753...33,563,373 		JBrowse link
G Sycp1 synaptonemal complex protein 1 located_in ISO (PMID:12584241), (PMID:23133398) MGI PMID:12584241 PMID:23133398 NCBI chrNW_004955435:18,157,173...18,291,732 JBrowse link
G Tex11 testis expressed 11 located_in ISO (PMID:18316482) MGI PMID:18316482 NCBI chrNW_004955475:10,057,708...10,432,087 JBrowse link
G Tex12 testis expressed 12 located_in ISO (PMID:16968740), (PMID:22164254), (PMID:22854038) MGI PMID:16968740 PMID:22164254 PMID:22854038 NCBI chrNW_004955412:13,829,637...13,834,481
Ensembl chrNW_004955412:13,831,353...13,834,481 		JBrowse link
lateral element term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase located_in ISO (PMID:10728666) UniProt PMID:10728666 NCBI chrNW_004955416:14,814,753...14,899,865
Ensembl chrNW_004955416:14,842,033...14,899,687 		JBrowse link
G Brca1 BRCA1 DNA repair associated located_in ISO (PMID:9774970) MGI PMID:9774970 NCBI chrNW_004955451:16,819,463...16,870,780
Ensembl chrNW_004955451:16,819,023...16,855,528 		JBrowse link
G Brca2 BRCA2 DNA repair associated located_in ISO (PMID:9774970) MGI PMID:9774970 NCBI chrNW_004955431:13,449,287...13,526,878
Ensembl chrNW_004955431:13,449,543...13,527,432 		JBrowse link
G Dmc1 DNA meiotic recombinase 1 located_in ISO (PMID:30718482) MGI PMID:30718482 NCBI chrNW_004955413:24,685,311...24,724,269
Ensembl chrNW_004955413:24,684,073...24,724,344 		JBrowse link
G Incenp inner centromere protein located_in ISO (PMID:19283064) MGI PMID:19283064 NCBI chrNW_004955511:5,705,948...5,724,167
Ensembl chrNW_004955511:5,706,201...5,720,772 		JBrowse link
G Kash5 KASH domain containing 5 located_in ISO (PMID:24062341) MGI PMID:24062341 NCBI chrNW_004955559:1,416,844...1,438,451 JBrowse link
G Mei4 meiotic double-stranded break formation protein 4 located_in ISO (PMID:20551173) MGI PMID:20551173 NCBI chrNW_004955502:5,835,608...6,017,945
Ensembl chrNW_004955502:5,831,658...6,018,521 		JBrowse link
G Rad21l1 RAD21 cohesin complex component like 1 located_in ISO (PMID:21743440) MGI PMID:21743440 NCBI chrNW_004955596:455,932...485,853
Ensembl chrNW_004955596:457,835...486,046 		JBrowse link
G Rad51 RAD51 recombinase located_in ISO (PMID:9774970)
(PMID:18694567), (PMID:21743440)		 MGI PMID:9774970 PMID:18694567 PMID:21743440 NCBI chrNW_004955416:7,566,715...7,590,628
Ensembl chrNW_004955416:7,566,686...7,590,628 		JBrowse link
G Rec8 REC8 meiotic recombination protein located_in ISO (PMID:15870106), (PMID:32328639) MGI PMID:15870106 PMID:32328639 NCBI chrNW_004955409:36,223,783...36,231,749
Ensembl chrNW_004955409:36,223,844...36,230,948 		JBrowse link
G Rpa1 replication protein A1 located_in ISO (PMID:21743440), (PMID:22711701) MGI PMID:21743440 PMID:22711701 NCBI chrNW_004955481:1,304,035...1,361,806 JBrowse link
G Smc1a structural maintenance of chromosomes 1A ISO MMO:0000662 RGD PMID:10652260 RGD:1331378 NCBI chrNW_004955475:421,472...468,286
Ensembl chrNW_004955475:421,409...468,324 		JBrowse link
G Smc1b structural maintenance of chromosomes 1B located_in ISO (PMID:15870106), (PMID:22711701) MGI PMID:15870106 PMID:22711701 NCBI chrNW_004955413:29,709,473...29,765,043
Ensembl chrNW_004955413:29,709,473...29,765,043 		JBrowse link
G Smc3 structural maintenance of chromosomes 3 located_in ISO (PMID:15870106), (PMID:22711701), (PMID:32328639) MGI PMID:15870106 PMID:22711701 PMID:32328639 NCBI chrNW_004955485:815,281...848,561 JBrowse link
G Stag3 STAG3 cohesin complex component located_in ISO (PMID:22711701) MGI PMID:22711701 NCBI chrNW_004955573:602,635...631,775
Ensembl chrNW_004955573:602,016...630,936 		JBrowse link
G Sycp2 synaptonemal complex protein 2 located_in ISO PMID:9933407
(PMID:18283110), (PMID:22011390), (PMID:22711701), (PMID:23133398)		 UniProt
MGI		 PMID:9933407 PMID:18283110 PMID:22011390 PMID:22711701 PMID:23133398 RGD:11035335 NCBI chrNW_004955528:3,809,438...3,887,055
Ensembl chrNW_004955528:3,809,438...3,886,312 		JBrowse link
G Sycp2l synaptonemal complex protein 2 like located_in ISO (PMID:26362258) MGI PMID:26362258 NCBI chrNW_004955465:3,440,106...3,518,840 JBrowse link
G Sycp3 synaptonemal complex protein 3 located_in ISO PMID:9933407
(PMID:10678170), (PMID:18802469), (PMID:19283064), (PMID:21539824), (PMID:21743440), (PMID:22011390), (PMID:22711701), (PMID:22854038), (PMID:23133398), (PMID:23555294), (PMID:25533956), (PMID:25675407)		 UniProt
MGI		 PMID:9933407 PMID:10678170 PMID:18802469 PMID:19283064 PMID:21539824 More... RGD:11035335 NCBI chrNW_004955405:37,093,330...37,102,789
Ensembl chrNW_004955405:37,093,652...37,102,856 		JBrowse link
transverse filament term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stag3 STAG3 cohesin complex component located_in ISO (PMID:15870106) MGI PMID:15870106 NCBI chrNW_004955573:602,635...631,775
Ensembl chrNW_004955573:602,016...630,936 		JBrowse link
G Sycp1 synaptonemal complex protein 1 located_in ISO (PMID:15870106), (PMID:18283110), (PMID:21539824), (PMID:22711701) RGD
MGI		 PMID:1464329 PMID:15870106 PMID:18283110 PMID:21539824 PMID:22711701 RGD:729937 NCBI chrNW_004955435:18,157,173...18,291,732 JBrowse link
G Sycp3 synaptonemal complex protein 3 located_in ISO (PMID:15870106) MGI PMID:15870106 NCBI chrNW_004955405:37,093,330...37,102,789
Ensembl chrNW_004955405:37,093,652...37,102,856 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 12839
    cellular anatomical structure 12686
      synaptonemal structure 40
        synaptonemal complex 40
          central element 8
          lateral element 18
          transverse filament 3
Path 2
Term Annotations click to browse term
  cellular_component 12839
    cellular anatomical structure 12686
      organelle 10121
        intracellular organelle 9744
          intracellular membrane-bounded organelle 8822
            nucleus 5359
              nuclear lumen 3674
                nuclear chromosome 191
                  condensed nuclear chromosome 72
                    synaptonemal structure 40
                      synaptonemal complex 40
                        central element 8
                        lateral element 18
                        transverse filament 3
paths to the root