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ONTOLOGY REPORT - ANNOTATIONS

Term:mitophagy
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Accession:GO:0000423 term browser browse the term
Definition:The selective autophagy process in which a mitochondrion is degraded by macroautophagy.
Comment:Note that this terms refers to the macroautophagy process and is named by common usage. Be aware that there are a separate micromitophagy and mitophagy by induced vacuole formation processes.
Synonyms:exact_synonym: macromitophagy
 xref: Reactome:R-HSA-5205647 "Mitophagy";   Wikipedia:Mitophagy


show annotations for term's descendants           Sort by:
mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07040864.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Abi2 abl-interactor 2 involved_in ISO (PMID:38081847) RGD PMID:38081847 NCBI chr 9:69,321,072...69,490,630
Ensembl chr 9:61,827,139...61,905,699 		JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 involved_in ISO
IEA
IBA		 UniProtKB:O60260|UniProtKB:Q99MQ3 (PMID:21753002), (PMID:25215947)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:21753002 PMID:25215947 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:98,156,626...98,345,876
Ensembl chr 3:77,700,936...77,890,221 		JBrowse link
G Arfip2 ARF interacting protein 2 involved_in ISO
IEA
ISS		 (PMID:33773106)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:33773106 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:169,387,484...169,392,290
Ensembl chr 1:159,974,201...159,980,336 		JBrowse link
G Arhgap26 Rho GTPase activating protein 26 involved_in ISO
IEA		 (PMID:38081847)
GO_REF:0000107		 RGD
Ensembl		 PMID:38081847 GO_REF:0000107 NCBI chr18:30,702,602...31,489,047
Ensembl chr18:30,838,671...31,235,194 		JBrowse link
G Atg10 autophagy related 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:23,843,695...24,133,459
Ensembl chr 2:22,108,426...22,398,233 		JBrowse link
G Atg13 autophagy related 13 involved_in IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:21855797)		 GO_Central
Ensembl
RGD		 PMID:21855797 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:98,102,831...98,136,741
Ensembl chr 3:77,645,790...77,681,043 		JBrowse link
G Atg14 autophagy related 14 involved_in ISO
IEA
IBA		 (PMID:23878393)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:23878393 GO_REF:0000033 GO_REF:0000107 NCBI chr15:23,275,457...23,306,817
Ensembl chr15:20,795,750...20,827,113 		JBrowse link
G Atg4a autophagy related 4A, cysteine peptidase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:109,453,712...109,553,758
Ensembl chr  X:104,665,345...104,765,268 		JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase involved_in ISO
IBA
IEA		 (PMID:33773106)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:33773106 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:101,729,772...101,761,456
Ensembl chr 9:94,282,509...94,314,103 		JBrowse link
G Atg4c autophagy related 4C, cysteine peptidase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:118,977,594...119,050,894
Ensembl chr 5:113,867,092...113,934,830 		JBrowse link
G Atg4d autophagy related 4D, cysteine peptidase involved_in ISO
IEA
IBA		 (PMID:33773106)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:33773106 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:28,083,902...28,093,491
Ensembl chr 8:19,807,766...19,817,321 		JBrowse link
G Atg5 autophagy related 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:49,380,835...49,471,826
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Atg7 autophagy related 7 involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:20080761)
UniProtKB:Q9BXM7 (PMID:19279012)		 Ensembl
GO_Central
RGD		 PMID:19279012 PMID:20080761 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Atg9a autophagy related 9A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:84,126,071...84,136,723
Ensembl chr 9:76,677,404...76,687,986 		JBrowse link
G Atg9b autophagy related 9B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:11,678,548...11,686,097
Ensembl chr 4:10,786,114...10,793,651 		JBrowse link
G Bcl2l13 Bcl2-like 13 acts_upstream_of_or_within ISO
IEA		 (PMID:31266807)
GO_REF:0000107		 RGD
Ensembl		 PMID:31266807 GO_REF:0000107 NCBI chr 4:155,728,284...155,785,058
Ensembl chr 4:154,056,127...154,108,985 		JBrowse link
G Becn1 beclin 1 involved_in ISO
IEA
IBA		 (PMID:23878393), (PMID:25215947)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:23878393 PMID:25215947 GO_REF:0000033 GO_REF:0000107 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Becn2 beclin 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:90,375,186...90,424,533
Ensembl chr13:87,844,531...87,845,787 		JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO
IEA		 (PMID:22505714)
GO_REF:0000107		 RGD
Ensembl		 PMID:22505714 GO_REF:0000107 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Clec16a C-type lectin domain containing 16A involved_in ISO
IEA		 (PMID:35604110)
GO_REF:0000107		 RGD
Ensembl		 PMID:35604110 GO_REF:0000107 NCBI chr10:5,434,725...5,631,246
Ensembl chr10:4,928,030...5,123,578 		JBrowse link
G Ctsk cathepsin K involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha involved_in ISO
IEA
ISS		 (PMID:38340717)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:38340717 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Fundc1 FUN14 domain containing 1 involved_in ISO
IEA		 UniProtKB:P09936 (PMID:34244144)
GO_REF:0000107		 RGD
Ensembl		 PMID:34244144 GO_REF:0000107 NCBI chr  X:7,666,787...7,683,443
Ensembl chr  X:5,083,617...5,100,284 		JBrowse link
G Gabarap GABA type A receptor-associated protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:55,213,465...55,216,787
Ensembl chr10:54,714,198...54,717,765 		JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:164,666,332...164,675,474
Ensembl chr 4:162,980,249...162,989,450 		JBrowse link
G Gabarapl2 GABA type A receptor associated protein like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:56,819,826...56,830,662
Ensembl chr19:39,910,534...39,924,628 		JBrowse link
G Gabarapl3 GABA type A receptor associated protein like 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:98,126,056...98,127,013
Ensembl chr 8:89,246,195...89,247,139 		JBrowse link
G Gabarapl4 gamma-aminobutyric acid receptor associated protein like 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:71,949,837...71,950,435
Ensembl chr19:55,052,756...55,053,109 		JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO
IEA		 (PMID:23707074)
GO_REF:0000107		 RGD
Ensembl		 PMID:23707074 GO_REF:0000107 NCBI chr 2:176,902,141...176,916,015
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Lrba LPS responsive beige-like anchor protein involved_in ISO (PMID:33773106) RGD PMID:33773106 NCBI chr 2:173,919,330...174,500,536
Ensembl chr 2:171,621,507...172,202,724 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
UniProtKB:Q9BXM7 (PMID:19279012), (PMID:28017329)		 UniProt
GO_Central
RGD		 PMID:19279012 PMID:28017329 GO_REF:0000024 GO_REF:0000033 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690 		JBrowse link
G Nipsnap1 nipsnap homolog 1 involved_in ISO
IEA		 (PMID:30982665)
GO_REF:0000107
GO_REF:0000117		 RGD
Ensembl
UniProt		 PMID:30982665 GO_REF:0000107 GO_REF:0000117 NCBI chr14:83,957,714...83,981,579
Ensembl chr14:79,734,209...79,758,098 		JBrowse link
G Nipsnap2 nipsnap homolog 2 involved_in ISO
IEA		 (PMID:30982665)
GO_REF:0000107
GO_REF:0000117		 RGD
Ensembl
UniProt		 PMID:30982665 GO_REF:0000107 GO_REF:0000117 NCBI chr12:32,542,171...32,580,345
Ensembl chr12:26,911,723...26,944,166 		JBrowse link
G Nipsnap3a nipsnap homolog 3A (C. elegans) involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 5:72,409,365...72,420,441
Ensembl chr 5:67,614,036...67,669,700 		JBrowse link
G Nipsnap3b nipsnap homolog 3B involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr 5:72,446,945...72,465,090
Ensembl chr 5:67,614,036...67,669,700 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA
ISO		 GO_REF:0000107
(PMID:33406421)		 Ensembl
RGD		 PMID:33406421 GO_REF:0000107 NCBI chr  X:70,811,317...70,856,123
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G Phb2 prohibitin 2 involved_in ISO
IEA
ISS		 (PMID:28017329)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:28017329 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:159,203,948...159,208,561
Ensembl chr 4:157,517,577...157,522,272 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in IMP
IEA
ISO		 GO_REF:0000107
UniProtKB:Q8CGY8 (PMID:33406421), (PMID:38081847)		 Ensembl
RGD		 PMID:33406421 PMID:38081847 PMID:25154397 GO_REF:0000107, RGD:12904014 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within		 IDA
IEA
IBA
ISO		 PMID:20457763
GO_REF:0000107
GO_REF:0000033
(PMID:23685073), (PMID:28017329)
MGI:1921624 (PMID:24949970)		 Ensembl
GO_Central
RGD		 PMID:23685073 PMID:24949970 PMID:28017329 PMID:20457763 GO_REF:0000033 GO_REF:0000107, RGD:10047224 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Retreg1 reticulophagy regulator 1 acts_upstream_of_or_within ISO (PMID:31446166) RGD PMID:31446166 NCBI chr 2:78,045,435...78,205,316
Ensembl chr 2:76,335,609...76,493,898 		JBrowse link
G Rimoc1 RAB7A interacting MON1-CCZ1 complex subunit 1 involved_in ISO
IEA		 (PMID:34432599)
GO_REF:0000107
GO_REF:0000002		 RGD
Ensembl
InterPro		 PMID:34432599 GO_REF:0000002 GO_REF:0000107 NCBI chr 2:54,917,383...54,931,577
Ensembl chr 2:53,189,790...53,203,821 		JBrowse link
G Snx30 sorting nexin family member 30 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:79,478,804...79,608,118
Ensembl chr 5:74,684,015...74,792,631 		JBrowse link
G Snx7 sorting nexin 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:208,528,041...208,612,597
Ensembl chr 2:205,842,837...205,927,763 		JBrowse link
G Spata33 spermatogenesis associated 33 involved_in ISO (PMID:33087875) RGD PMID:33087875 NCBI chr19:68,155,033...68,167,415
Ensembl chr19:51,246,514...51,258,894 		JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO
IEA
IBA		 UniProtKB:Q9JK66 (PMID:20457763)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:20457763 GO_REF:0000033 GO_REF:0000107 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of ISO
IEA		 MGI:5319187 (PMID:22044588)
GO_REF:0000107		 RGD
Ensembl		 PMID:22044588 GO_REF:0000107 NCBI chr 4:161,613,306...161,632,248
Ensembl chr 4:159,927,139...159,946,029
Ensembl chr 6:159,927,139...159,946,029 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of ISO
IEA		 MGI:1857263 (PMID:22044588)
GO_REF:0000107		 RGD
Ensembl		 PMID:22044588 GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 involved_in ISO
IBA		 (PMID:21855797)
GO_REF:0000033		 RGD
GO_Central		 PMID:21855797 GO_REF:0000033 NCBI chr12:51,511,492...51,537,746
Ensembl chr12:45,851,710...45,877,966 		JBrowse link
G Ulk2 unc-51 like autophagy activating kinase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:46,951,038...47,029,844
Ensembl chr10:46,454,030...46,530,407 		JBrowse link
G Ulk3 unc-51 like kinase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:66,888,820...66,895,380
Ensembl chr 8:57,992,723...57,999,467 		JBrowse link
negative regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec16a C-type lectin domain containing 16A acts_upstream_of_or_within ISO MGI:5648633 (PMID:24949970) RGD PMID:24949970 NCBI chr10:5,434,725...5,631,246
Ensembl chr10:4,928,030...5,123,578 		JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:38992176)		 Ensembl
RGD		 PMID:38992176 GO_REF:0000107 NCBI chr 5:40,752,513...40,826,154
Ensembl chr 5:35,955,812...36,029,443 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IEA		 (PMID:19279012)
GO_REF:0000107		 RGD
Ensembl		 PMID:19279012 GO_REF:0000107 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Pptc7 protein phosphatase targeting COQ7 involved_in IEA
ISO		 GO_REF:0000107
(PMID:38992176)		 Ensembl
RGD		 PMID:38992176 GO_REF:0000107 NCBI chr12:39,910,728...39,949,101
Ensembl chr12:34,249,977...34,288,339 		JBrowse link
G Rnf41 ring finger protein 41 acts_upstream_of_or_within ISO
IEA		 MGI:1921624 (PMID:24949970)
GO_REF:0000107		 RGD
Ensembl		 PMID:24949970 GO_REF:0000107 NCBI chr 7:1,422,651...1,461,700
Ensembl chr 7:838,203...865,511 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO
IEA		 MGI:5319187 (PMID:22044588)
GO_REF:0000107		 RGD
Ensembl		 PMID:22044588 GO_REF:0000107 NCBI chr 4:161,613,306...161,632,248
Ensembl chr 4:159,927,139...159,946,029
Ensembl chr 6:159,927,139...159,946,029 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO
IEA		 MGI:1857263 (PMID:22044588)
GO_REF:0000107		 RGD
Ensembl		 PMID:22044588 GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tspo translocator protein involved_in ISO
IEA		 (PMID:25470454)
GO_REF:0000107		 RGD
Ensembl		 PMID:25470454 GO_REF:0000107 NCBI chr 7:116,600,214...116,610,461
Ensembl chr 7:114,720,188...114,730,450 		JBrowse link
G Usp30 ubiquitin specific peptidase 30 IMP RGD PMID:24896179 RGD:13208875 NCBI chr12:48,161,905...48,215,878
Ensembl chr12:42,501,348...42,555,616 		JBrowse link
negative regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htra2 HtrA serine peptidase 2 involved_in ISO
IEA		 (PMID:24709290)
GO_REF:0000107		 RGD
Ensembl		 PMID:24709290 GO_REF:0000107 NCBI chr 4:117,114,631...117,117,793
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Vps13c vacuolar protein sorting 13 homolog C involved_in ISO
IEA
ISS		 (PMID:26942284)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
ParkinsonsUK-UCL		 PMID:26942284 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:77,359,499...77,533,009
Ensembl chr 8:68,478,395...68,651,895 		JBrowse link
positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy and beclin 1 regulator 1 involved_in ISO
IEA		 (PMID:30217973)
GO_REF:0000107		 RGD
Ensembl		 PMID:30217973 GO_REF:0000107 NCBI chr 3:98,156,626...98,345,876
Ensembl chr 3:77,700,936...77,890,221 		JBrowse link
G Atg7 autophagy related 7 IMP RGD PMID:37042059 RGD:407532700 NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO (PMID:22922758) RGD PMID:22922758 NCBI chr16:19,131,271...19,146,480
Ensembl chr16:19,104,466...19,112,519 		JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 involved_in ISO
IEA		 (PMID:38340717)
GO_REF:0000107		 RGD
Ensembl		 PMID:38340717 GO_REF:0000107 NCBI chr18:30,325,369...30,349,285
Ensembl chr18:30,085,126...30,098,756 		JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in ISO
IEA
ISS		 (PMID:38340717)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:38340717 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,824,431...15,858,266
Ensembl chr12:10,705,874...10,744,573 		JBrowse link
G Fbxo7 F-box protein 7 involved_in IMP
IEA
ISO		 PMID:26310625
GO_REF:0000107
(PMID:26310625)		 Ensembl
RGD		 PMID:26310625 PMID:26310625 GO_REF:0000107, RGD:11536096 NCBI chr 7:19,696,951...19,725,180
Ensembl chr 7:17,809,231...17,837,530 		JBrowse link
G Gdf1 growth differentiation factor 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr16:19,131,271...19,146,480
Ensembl chr16:19,097,314...19,112,519 		JBrowse link
G Htt huntingtin involved_in IEA
ISO		 GO_REF:0000107
(PMID:25686248)		 Ensembl
RGD		 PMID:25686248 GO_REF:0000107 NCBI chr14:80,070,456...80,219,668
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:33510463)
(PMID:21102437)
(PMID:32939830)		 UniProt
Ensembl
RGD		 PMID:21102437 PMID:32939830 PMID:33510463 GO_REF:0000024 GO_REF:0000107 NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:31919280) RGD PMID:31919280 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IMP
IEA
ISO		 GO_REF:0000107
(PMID:26310625)		 Ensembl
RGD		 PMID:26310625 PMID:28608965 GO_REF:0000107, RGD:13432560 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:31618756)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:31618756 GO_REF:0000024 GO_REF:0000107 NCBI chr16:52,805,521...52,809,316
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISS
ISO		 GO_REF:0000024
(PMID:31618756)		 UniProt
RGD		 PMID:31618756 GO_REF:0000024 NCBI chr  X:120,897,616...120,900,683
Ensembl chr  X:116,031,803...116,034,967 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in IMP PMID:29934347 UniProt PMID:29934347 RGD:405650300 NCBI chr10:15,355,278...15,357,559
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Ube2a ubiquitin-conjugating enzyme E2A involved_in ISO
IEA		 (PMID:23685073)
GO_REF:0000107		 RGD
Ensembl		 PMID:23685073 GO_REF:0000107 NCBI chr  X:120,979,993...120,990,773
Ensembl chr  X:116,113,875...116,125,070 		JBrowse link
G Vps13d vacuolar protein sorting 13 homolog D involved_in ISO
IEA		 (PMID:29307555)
GO_REF:0000107		 RGD
Ensembl		 PMID:29307555 GO_REF:0000107 NCBI chr 5:162,113,732...162,339,121
Ensembl chr 5:156,830,512...157,055,891 		JBrowse link
positive regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISO (PMID:24005319) RGD PMID:24005319 NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:144,738,950...144,742,668 		JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone involved_in ISO (PMID:21855797) RGD PMID:21855797 NCBI chr 8:27,954,292...27,966,935
Ensembl chr 8:19,671,938...19,690,809 		JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO
IEA		 (PMID:23707074)
GO_REF:0000107		 RGD
Ensembl		 PMID:23707074 GO_REF:0000107 NCBI chr 2:176,902,141...176,916,015
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Hdac6 histone deacetylase 6 involved_in ISO
IEA		 UniProtKB:Q9JK66 (PMID:20457763)
GO_REF:0000107		 RGD
Ensembl		 PMID:20457763 GO_REF:0000107 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
G Hk2 hexokinase 2 involved_in ISO
IEA		 (PMID:23962723)
GO_REF:0000107		 RGD
Ensembl		 PMID:23962723 GO_REF:0000107 NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Huwe1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in ISO (PMID:30217973) RGD PMID:30217973 NCBI chr  X:24,350,708...24,480,798
Ensembl chr  X:20,873,795...21,001,262 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO
IEA		 (PMID:24709290)
GO_REF:0000107		 RGD
Ensembl		 PMID:24709290 GO_REF:0000107 NCBI chr 5:155,936,112...155,945,163
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IEA		 (PMID:20871098)
GO_REF:0000107		 RGD
Ensembl		 PMID:20871098 GO_REF:0000107 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA		 (PMID:20457763), (PMID:20871098), (PMID:23212910)
GO_REF:0000107		 RGD
Ensembl		 PMID:20457763 PMID:20871098 PMID:23212910 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 involved_in ISO (PMID:24270810) RGD PMID:24270810 NCBI chr 4:12,197,503...12,204,344
Ensembl chr 4:11,305,110...11,311,962 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in ISO
IEA		 (PMID:32047033)
GO_REF:0000107		 RGD
Ensembl		 PMID:32047033 GO_REF:0000107 NCBI chr10:37,029,377...37,060,542
Ensembl chr10:36,532,244...36,559,640 		JBrowse link
regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:31172217 RGD:329403053 NCBI chr13:80,280,595...80,366,939
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like involved_in ISO
IEA		 UniProtKB:Q9Z2F7 (PMID:20200478)
GO_REF:0000107		 RGD
Ensembl		 PMID:20200478 GO_REF:0000107 NCBI chr15:45,350,081...45,373,213
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr19:9,562,340...9,602,136
Ensembl chr19:9,556,260...9,596,080 		JBrowse link
G Cttn cortactin involved_in IEA
ISO		 GO_REF:0000107
(PMID:20457763)		 Ensembl
RGD		 PMID:20457763 GO_REF:0000107 NCBI chr 1:209,029,048...209,064,577
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Dnm1l dynamin 1-like involved_in ISO UniProtKB:Q9BXM7 (PMID:19279012) RGD PMID:19279012 NCBI chr11:98,084,049...98,135,663
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO
IEA		 (PMID:24912190)
GO_REF:0000107		 RGD
Ensembl		 PMID:24912190 GO_REF:0000107 NCBI chr 2:172,447,738...172,609,591
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 involved_in ISO
IEA		 (PMID:28381481), (PMID:31908024)
GO_REF:0000107		 RGD
Ensembl		 PMID:28381481 PMID:31908024 GO_REF:0000107 NCBI chr16:18,929,581...18,936,621
Ensembl chr16:18,893,576...18,902,612 		JBrowse link
G Fzd5 frizzled class receptor 5 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 9:73,606,860...73,614,039
Ensembl chr 9:66,113,112...66,121,457 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (PMID:24912190) RGD PMID:24912190 NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISO (PMID:21355049) RGD PMID:21355049 NCBI chr11:94,097,559...94,124,915
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in ISO
IEA		 (PMID:24912190)
GO_REF:0000107		 RGD
Ensembl		 PMID:24912190 GO_REF:0000107 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
G Usp36 ubiquitin specific peptidase 36 involved_in ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr10:103,995,970...104,027,492
Ensembl chr10:103,497,349...103,528,877 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in ISO
IEA		 (PMID:25470454)
GO_REF:0000107		 RGD
Ensembl		 PMID:25470454 GO_REF:0000107 NCBI chr10:37,029,377...37,060,542
Ensembl chr10:36,532,244...36,559,640 		JBrowse link
type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac6 histone deacetylase 6 involved_in ISO
IEA		 UniProtKB:Q9JK66|UniProtKB:Q9Z2V5 (PMID:20457763)
GO_REF:0000107		 RGD
Ensembl		 PMID:20457763 GO_REF:0000107 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
G Mfn2 mitofusin 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:23620051)		 Ensembl
RGD		 PMID:23620051 GO_REF:0000107 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Optn optineurin involved_in ISO
IEA		 (PMID:25294927)
GO_REF:0000107		 RGD
Ensembl		 PMID:25294927 GO_REF:0000107 NCBI chr17:78,118,847...78,169,543
Ensembl chr17:73,209,575...73,260,251 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA		 (PMID:19029340)
GO_REF:0000107		 RGD
Ensembl		 PMID:19029340 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in ISO (PMID:22020285) RGD PMID:22020285 NCBI chr12:14,748,717...14,840,273
Ensembl chr12:9,635,025...9,726,519 		JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 involved_in ISS
ISO		 GO_REF:0000024
(PMID:37160114)		 UniProt
RGD		 PMID:37160114 GO_REF:0000024 NCBI chr16:7,416,590...7,442,681
Ensembl chr16:7,409,688...7,436,379
Ensembl chr 3:7,409,688...7,436,379
Ensembl chr 6:7,409,688...7,436,379 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      process utilizing autophagic mechanism 564
        autophagy 564
          autophagy of mitochondrion 115
            mitophagy 97
              negative regulation of mitophagy + 11
              positive regulation of mitophagy + 26
              regulation of mitophagy + 49
              type 1 mitophagy 0
              type 2 mitophagy + 17
Path 2
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      metabolic process 12206
        catabolic process 2970
          autophagy 564
            macroautophagy 335
              mitophagy 97
                negative regulation of mitophagy + 11
                positive regulation of mitophagy + 26
                regulation of mitophagy + 49
                type 1 mitophagy 0
                type 2 mitophagy + 17
paths to the root