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EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS


Term:extranodal nasal NK/T cell lymphoma
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Accession:EFO:MONDO:0019472 term browser browse the term
Definition:Extranodal nasal NK/T cell lymphoma (NKTCL) is a rare, malignant neoplasm mainly affecting men in the fifth decade of life, that usually arises in the nose, paranasal sinuses, orbits or upper airway, and that can present with a nasal mass, nasal bleeding, nasal obstruction, palate perforation (i.e. midline perforation of the hard palate), and mid-facial and/or upper airway destructive lesions. In advanced disease stages, which are associated with a poor prognosis, NKTCL may disseminate to other organs. A few cases of NKTCL presenting primarily in the lymph nodes have also been described.
Synonyms:exact_synonym: Extranodal NK/T lymphoma-nasal;   NK/T-cell lymphoma;   NKTCL;   angiocentric T-cell lymphoma;   lethal midline granuloma;   nasal T/natural killer-cell lymphoma;   nasal type Extranodal NK/T-cell lymphoma;   reticulosis, malignant
 alt_id: MONDO:0019472
 xref: DOID:0080797;   GARD:7041;   ICDO:9719/3;   MEDGEN:140278;   MedDRA:10065855;   NANDO:2200027;   NCI:C4684;   ORDO:86879;   UMLS:C0392788;   icd11.foundation:684005900



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  experimental factor 0
    material property 0
      disposition 0
        disease 0
          hematologic disease 0
            hematopoietic and lymphoid system neoplasm 0
              Genetic tumor of hematopoietic and lymphoid tissues 0
                lymphoma 0
                  extranodal nasal NK/T cell lymphoma 0
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  experimental factor 0
    material property 0
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          cancer or benign tumor 0
            neoplastic disease or syndrome 0
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                hematopoietic and lymphoid system neoplasm 0
                  hematopoietic and lymphoid cell neoplasm 0
                    lymphoid neoplasm 0
                      lymphoma 0
                        extranodal nasal NK/T cell lymphoma 0
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