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EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS

Term:tuberculosis
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Accession:EFO:MONDO:0018076 term browser browse the term
Definition:A chronic, recurrent infection caused by the bacterium Mycobacterium tuberculosis. Tuberculosis (TB) may affect almost any tissue or organ of the body with the lungs being the most common site of infection. The clinical stages of TB are primary or initial infection, latent or dormant infection, and recrudescent or adult-type TB. Ninety to 95% of primary TB infections may go unrecognized. Histopathologically, tissue lesions consist of granulomas which usually undergo central caseation necrosis. Local symptoms of TB vary according to the part affected; acute symptoms include hectic fever, sweats, and emaciation; serious complications include granulomatous erosion of pulmonary bronchi associated with hemoptysis. If untreated, progressive TB may be associated with a high degree of mortality. This infection is frequently observed in immunocompromised individuals with AIDS or a history of illicit IV drug use.
Synonyms:exact_synonym: tuberculosis disease
 narrow_synonym: active tuberculosis
 related_synonym: Kochs disease;   TB
 alt_id: MONDO:0018076
 xref: DOID:399;   GARD:7827;   ICD10CM:A15-A19;   ICD9:017.90;   ICD9:017.92;   ICD9:017.94;   ICD9:017.96;   MEDGEN:22513;   MESH:D014376;   MedDRA:10044755;   NCI:C3423;   NORD:1801;   ORDO:3389;   SCTID:56717001;   UMLS:C0041296;   icd11.foundation:2072728114
 see_also: https://rarediseases.info.nih.gov/diseases/7827/tuberculosis" xsd:anyURI {source="GARD:0007827


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  experimental factor 0
    material property 0
      disposition 0
        disease 0
          infectious disease 0
            bacterial disease 0
              mycobacterial infectious disease 0
                tuberculosis 0
                  drug-resistant tuberculosis + 0
                  endocrine tuberculosis + 0
                  extrapulmonary tuberculosis + 0
                  pulmonary tuberculosis + 0
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