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EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS

Term:esophageal leukoplakia
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Accession:EFO:MONDO:0004697 term browser browse the term
Definition:A rare condition that usually affects the middle-to-distal esophagus in middle-aged and elderly people. There is usually a history of tobacco smoking or alcohol intake. Dysphagia is the presenting symptom. Morphologically, the lesions are well-demarcated and are characterized by epithelial hyperplasia, thickened basal layer, prominent granular cell layer, and hyperorthokeratosis. In a minority of patients this condition is associated with adjacent high-grade squamous dysplasia and/or squamous cell carcinoma.
Synonyms:exact_synonym: esophageal epidermoid metaplasia;   esophageal leukoplakia (disease);   esophagus leukoplakia;   leukoplakia of esophagus;   leukoplakia of oesophagus;   leukoplakia of the esophagus;   leukoplakia of the oesophagus;   oesophagus leukoplakia
 alt_id: MONDO:0004697
 xref: DOID:9021;   HP:0012859;   ICD9:530.83;   MEDGEN:75628;   NCI:C3953;   SCTID:89057003;   UMLS:C0267095


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  experimental factor 0
    material property 0
      disposition 0
        disease 0
          digestive system disease 0
            esophageal disease 0
              esophageal leukoplakia 0
Path 2
Term Annotations click to browse term
  experimental factor 0
    material property 0
      disposition 0
        disease 0
          cancer or benign tumor 0
            precancerous condition 0
              leukoplakia 0
                esophageal leukoplakia 0
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