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EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS

Term:Mode of inheritance
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Accession:EFO:HP:0000005 term browser browse the term
Definition:The pattern in which a particular genetic trait or disorder is passed from one generation to the next.
Comment:While there is a close conceptual relationship between allelic requirement and inheritance, they serve different purposes; allelic requirement is necessary for variant annotation pipelines and to determine if a given variant in a specific context is relevant to the phenotype of the patient e.g. a heterozygous variant (in the absence of compound heterozygosity) is relevant for dominant but not for recessive disease; while inheritance is used for describing the mode of inheritance of a phenotype and is particularly applicable in the clinical setting for communicating recurrence risk, to guide family screening, and to guide reproductive advice.
Synonyms:exact_synonym: Inheritance
 alt_id: HP:0000005;   HP:0001425;   HP:0001453;   HP:0001461;   HP:0010985
 xref: UMLS:C1708511


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  experimental factor 0
    material property 0
      disposition 0
        Mode of inheritance 0
          Autosomal dominant inheritance 0
          Autosomal recessive inheritance 0
          Mitochondrial inheritance 0
          X-linked inheritance + 0
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