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EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS

Term:renal fibrosis
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Accession:EFO:1001517 term browser browse the term
Definition:A final common manifestation of a wide variety of chronic kidney diseases characterized by glomerulosclerosis and tubulointerstitial fibrosis. Renal fibrosis is the inevitable consequence of an excessive accumulation of extracellular matrix that occurs in virtually every type of chronic kidney disease. The pathogenesis of renal fibrosis is a progressive process that ultimately leads to end-stage renal failure, a devastating disorder that requires dialysis or kidney transplantation.
Synonyms:exact_synonym: kidney fibrosis
 xref: DOID:0050855;   HP:0030760;   MEDGEN:508798;   MONDO:0000494;   MP:0003985;   PMID:16408108;   SCTID:197660000;   SNOMEDCT:197660000;   UMLS:C0151650


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Path 1
Term Annotations click to browse term
  experimental factor 0
    material property 0
      disposition 0
        disease 0
          urinary system disease 0
            kidney disease 0
              kidney neoplasm 0
                renal fibrosis 0
Path 2
Term Annotations click to browse term
  experimental factor 0
    material property 0
      disposition 0
        disease 0
          cancer or benign tumor 0
            neoplastic disease or syndrome 0
              neoplasm 0
                urinary system neoplasm 0
                  kidney neoplasm 0
                    renal fibrosis 0
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