Digestive System Adenoma - Ontology Report

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Term:	Digestive System Adenoma	go back to main search page
Accession:	EFO:1000217	browse the term
Definition:	A sporadic or less frequently familial neoplasm, arising from the glandular epithelium of the stomach, small intestine, biliary tract, colon, and rectum. It is a polypoid or flat circumscribed lesion. Morphologically, it is characterized by a proliferation of neoplastic glandular cells and it is associated with dysplasia. According to the growth pattern, it may be classified as tubular, villous, or tubulovillous. The dysplasia is classified as mild, moderate, or severe. The frequency of malignant transformation depends on the size of the lesion and the degree of dysplasia. Larger adenomas with severe dysplastic changes (sometimes called carcinoma in situ) carry a higher risk of progressing to invasive adenocarcinoma. Gastrointestinal adenomas may present as solitary or multifocal lesions. Familial adenomas tend to be multifocal and carry a higher risk of malignant transformation.
Synonyms:	exact_synonym:	DOID:4147; GI adenoma; NCIT:C36207; digestive tract adenoma; gastrointestinal adenoma; http://identifiers.org/medgen/184920; http://linkedlifedata.com/resource/umls/id/C0948101
	xref:	DOID:4147; MEDGEN:184920; MONDO:0006180; NCI:C36207; UMLS:C0948101
	external_ontology:	disease_has_location EFO:UBERON:0001555

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Term paths to the root

Path 1
Term	Annotations
experimental factor	0
material property	0
disposition	0
disease	0
digestive system disease	0
Digestive System Adenoma	0
Bile Duct Adenoma +	0
Gallbladder Adenoma	0
Gastric Adenoma +	0
Warthin Tumor	0
adenoma of small intestine +	0
colorectal adenoma +	0
sessile serrated polyp	0
Path 2
Term	Annotations
experimental factor	0
material property	0
disposition	0
disease	0
cancer or benign tumor	0
neoplastic disease or syndrome	0
neoplasm	0
epithelial neoplasm	0
adenoma	0
Digestive System Adenoma	0
Bile Duct Adenoma +	0
Gallbladder Adenoma	0
Gastric Adenoma +	0
Warthin Tumor	0
adenoma of small intestine +	0
colorectal adenoma +	0
sessile serrated polyp	0

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