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EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS


Term:respiratory failure
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Accession:EFO:0009686 term browser browse the term
Definition:The significant impairment of gas exchange within the lungs resulting in hypoxia, hypercarbia, or both, to the extent that organ tissue perfusion is severely compromised. Causes include chronic obstructive pulmonary disease, asthma, emphysema, acute respiratory distress syndrome, pneumonia, pulmonary edema, pneumothorax, and congestive heart failure. Treatment requires intubation and mechanical ventilation until the time the lungs recover sufficient function. The significant impairment of gas exchange within the lungs resulting in hypoxia, hypercarbia, or both, to the extent that organ tissue perfusion is severely compromised. Causes include chronic obstructive pulmonary disease, asthma, emphysema, acute respiratory distress syndrome, pneumonia, pulmonary edema, pneumothorax, and congestive heart failure. Treatment requires intubation and mechanical ventilation until the time the lungs recover sufficient function. [NCIt:C26872]
Synonyms:exact_synonym: respiratory insufficiency/failure
 narrow_synonym: acute respiratory failure;   chronic respiratory failure
 related_synonym: acute and chronic respiratory failure;   acute-on-chronic respiratory failure
 xref: DOID:11162;   ICD10:J96;   ICD9:518.81;   ICD9:518.83;   MEDGEN:257837;   MESH:D012131;   MONDO:0021113;   MedDRA:10038695;   NCI:C26872;   SCTID:39871006;   UMLS:C1145670;   icd11.foundation:370028006
 external_ontology: disease_disrupts EFO:GO:0007585



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  experimental factor 0
    material property 0
      disposition 0
        disease 0
          respiratory system disease 0
            lower respiratory tract disease 0
              lung disease 0
                respiratory failure 0
                  acute respiratory failure + 0
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