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EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS


Term:pneumocystosis
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Accession:EFO:0007448 term browser browse the term
Definition:An opportunistic mycosis that is located_in lungs, but can also occur in eyes, ears, skin, thyroid, pituitary, palate, parathyroid, esophagus, pleura, heart, liver, spleen, small intestine, adrenals, kidneys, bone marrow, and lymph nodes, has_material_basis_in Pneumocystis jirovecii that effects interstitial and alveolar tissues and has_symptom nonproductive cough, has_symptom shortness of breath, and has_symptom fever. Human pneumocystosis is caused by an infectious agent, which (after recent nomenclature and taxonomy revisions) is now classed as the fungus Pneumocystis jiroveci. The prevalence is unknown. Pneumocystis jiroveci is an opportunistic infectious agent, developing in immunosuppressed patients. It is an air-borne infection, localized to the lungs. However, extrapulmonary involvement is seen in AIDS patients. The disease manifests progressively with coughing, respiratory problems (dyspnea) and fever, followed by acute respiratory insufficiency and death within a few weeks in untreated cases. The most reliable diagnostic method is bronchoalveolar lavage. The treatment of choice is cotrimoxazole.
Synonyms:exact_synonym: DOID:11339;   NCIT:C3334;   Orphanet:723;   PCP;   PJP;   Pneumocystis;   Pneumocystis carinii pneumonia;   Pneumocystis jirovecii pneumonia;   Pneumocystis pneumonia;   Pneumocystosis pneumonia;   http://identifiers.org/medgen/777048;   http://identifiers.org/mesh/D011020;   http://identifiers.org/snomedct/415125002;   http://linkedlifedata.com/resource/umls/id/C1535939;   http://purl.bioontology.org/ontology/ICD10CM/B59;   http://purl.obolibrary.org/obo/mondo/sources/icd11foundation/404370038;   pulmonary pneumocystosis;   pulmonary pneumocystosis (disorder)
 xref: DOID:11339;   GARD:4386;   ICD10CM:B59;   ICD10EXP:B59+;   ICD10EXP:J17.3*;   ICD9:136.3;   MEDGEN:777048;   MESH:D011020;   MONDO:0019121;   MedDRA:10035662;   NCI:C3334;   NORD:1923;   ORDO:723;   SCTID:415125002;   UMLS:C1535939;   icd11.foundation:404370038
 see_also: https://rarediseases.info.nih.gov/diseases/4386/pneumocystosis" xsd:anyURI {source="GARD:0004386



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  experimental factor 0
    material property 0
      disposition 0
        disease 0
          infectious disease 0
            fungal infectious disease 0
              Pneumocystis infectious disease 0
                pneumocystosis 0
Path 2
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  experimental factor 0
    material property 0
      disposition 0
        disease 0
          respiratory system disease 0
            lower respiratory tract disease 0
              lung disease 0
                pneumonitis 0
                  pneumonia 0
                    pneumocystosis 0
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