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EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS

Term:atrial natriuretic factor measurement
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Accession:EFO:0004789 term browser browse the term
Definition:Is a quantification of the 126-amino acid C-terminal fragment of the ANP precursor, an approximately 150-amino acid polypeptide in a number of species. It is formed by the removal of the N-terminal signal sequence ANP (1-24). This prohormone contains various active ANF sequences.\nANF is is a powerful vasodilator, and a protein (polypeptide) hormone secreted by heart muscle cells.[1][2][3] It is involved in the homeostatic control of body water, sodium, potassium and fat (adipose tissue). Increased levels of ANP are associated with heart failure.
Comment:is about MeSH:D017461
Synonyms:xref: CMO:0003505;   CMO:0003868
 external_ontology: is_about is_about EFO:0003144;   is_about EFO:CHEBI:24621;   is_about EFO:UBERON:0004535


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  experimental factor 0
    information entity 0
      measurement 0
        hormone measurement 0
          atrial natriuretic factor measurement 0
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  experimental factor 0
    information entity 0
      measurement 0
        cardiovascular measurement 0
          cardiovascular disease biomarker measurement 0
            atrial natriuretic factor measurement 0
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