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EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS

Term:carcinogen role
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Definition:Any chemical, biological or physical agents that increase the risk of neoplasms in humans or animals. Carcinogens include natural or synthesized compounds, certain viruses, and various sources of radiation. A carcinogen may directly alter the genetic material of cells (genotoxic), thereby initiating or promoting the process of malignant transformation; it also may induce cancers by mechanisms that do not involve a direct alteration of cellular genetic material (non-genotoxic). (NCI04)
Synonyms:exact_synonym: Carcinogen;   carcinogenic agent
 xref: NCI:C347


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