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EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS

Term:chronic kidney disease
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Accession:EFO:0003884 term browser browse the term
Definition:Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002) Impairment of the renal function secondary to chronic kidney damage persisting for three or more months. The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
Synonyms:exact_synonym: CKD;   CKD - chronic kidney disease;   Chronic Kidney Insufficiencies;   Chronic Kidney Insufficiency;   Chronic Renal Failure;   Chronic Renal Insufficiencies;   DOID:784;   END STAGE KIDNEY DIS;   END STAGE RENAL DIS;   ESRD;   End Stage Kidney Disease;   End Stage Renal Disease;   End-Stage Renal Failure;   NCIT:C80078;   chronic kidney failure;   chronic renal disease;   http://identifiers.org/medgen/473458;   http://identifiers.org/mesh/D007676;   http://identifiers.org/snomedct/709044004;   http://linkedlifedata.com/resource/umls/id/C1561643;   http://purl.bioontology.org/ontology/ICD10CM/N18.9;   http://purl.obolibrary.org/obo/mondo/sources/icd11foundation/412389819
 narrow_synonym: chronic renal failure syndrome
 related_synonym: chronic renal insufficiency
 xref: DOID:784;   HP:0012622;   ICD10:N18;   ICD10CM:N18.9;   ICD9:585;   ICD9:585.6;   MEDGEN:473458;   MESH:D007676;   MESH:D051436;   MONDO:0005300;   MedDRA:10038444;   MedDRA:10064848;   NANDO:2100008;   NANDO:2100023;   NCI:C80078;   SCTID:709044004;   SNOMEDCT:46177005;   SNOMEDCT:90688005;   UMLS:C1561643;   icd11.foundation:412389819


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Path 1
Term Annotations click to browse term
  experimental factor 0
    material property 0
      disposition 0
        disease 0
          chronic disease 0
            chronic kidney disease 0
              chronic pyelonephritis + 0
              chronic rapidly progressive glomerulonephritis 0
              chronic renal failure syndrome 0
              congenital chronic kidney disease 0
              diabetic nephropathy + 0
              stage 5 chronic kidney disease 0
Path 2
Term Annotations click to browse term
  experimental factor 0
    material property 0
      disposition 0
        disease 0
          urinary system disease 0
            kidney disease 0
              chronic kidney disease 0
                chronic pyelonephritis + 0
                chronic rapidly progressive glomerulonephritis 0
                chronic renal failure syndrome 0
                congenital chronic kidney disease 0
                diabetic nephropathy + 0
                stage 5 chronic kidney disease 0
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