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EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS

Term:large cell neuroendocrine carcinoma
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Accession:EFO:0000563 term browser browse the term
Definition:A usually aggressive carcinoma composed of large malignant cells which display neuroendocrine characteristics. It is characterized by the presence of high mitotic activity and necrotic changes. The vast majority of cases are positive for neuron-specific enolase. Representative examples include lung, breast, cervical, and thymic neuroendocrine carcinomas.
Synonyms:exact_synonym: LCNEC;   large cell NEC
 xref: DOID:0050872;   ICDO:8013/3;   MEDGEN:220402;   MONDO:0005057;   NCI:C6875;   ONCOTREE:LUNE;   UMLS:C1265996;   icd11.foundation:1278312485
 external_ontology: has_disease_location EFO:UBERON:0000949


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Path 1
Term Annotations click to browse term
  experimental factor 0
    material property 0
      disposition 0
        disease 0
          endocrine system disease 0
            endocrine neoplasm 0
              malignant endocrine neoplasm 0
                neuroendocrine carcinoma 0
                  large cell neuroendocrine carcinoma 0
                    Cervical Large Cell Neuroendocrine Carcinoma 0
                    Pancreatic Large Cell Neuroendocrine Carcinoma 0
                    breast large cell neuroendocrine carcinoma 0
                    ovarian large-cell neuroendocrine carcinoma 0
                    pulmonary large cell neuroendocrine carcinoma 0
                    thymic large cell neuroendocrine carcinoma 0
Path 2
Term Annotations click to browse term
  experimental factor 0
    material property 0
      disposition 0
        disease 0
          cancer or benign tumor 0
            neoplastic disease or syndrome 0
              neoplasm 0
                epithelial neoplasm 0
                  carcinoma 0
                    neuroendocrine carcinoma 0
                      large cell neuroendocrine carcinoma 0
                        Cervical Large Cell Neuroendocrine Carcinoma 0
                        Pancreatic Large Cell Neuroendocrine Carcinoma 0
                        breast large cell neuroendocrine carcinoma 0
                        ovarian large-cell neuroendocrine carcinoma 0
                        pulmonary large cell neuroendocrine carcinoma 0
                        thymic large cell neuroendocrine carcinoma 0
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