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EXPERIMENTAL FACTOR ONTOLOGY - ANNOTATIONS

Term:basal-like breast carcinoma
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Accession:EFO:0000281 term browser browse the term
Definition:A biologic subset of breast carcinoma defined by high expression of genes characteristic of basal epithelial cells, including KRT5 and KRT17, annexin 8, CX3CL1, and TRIM29, and usually by lack of expression of the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). It is the most common subtype of breast cancer associated with BRCA1 mutations, and is associated with a poor prognosis.
Synonyms:exact_synonym: basal-like breast cancer;   basal-like subtype of breast carcinoma
 xref: DOID:3458;   MEDGEN:770987;   MONDO:0004984;   NCI:C53558;   UMLS:C3642347


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Path 1
Term Annotations click to browse term
  experimental factor 0
    material property 0
      disposition 0
        disease 0
          breast disease 0
            breast neoplasm 0
              breast cancer 0
                breast carcinoma 0
                  Invasive Breast Carcinoma 0
                    invasive breast ductal carcinoma 0
                      basal-like breast carcinoma 0
Path 2
Term Annotations click to browse term
  experimental factor 0
    material property 0
      disposition 0
        disease 0
          cancer or benign tumor 0
            neoplastic disease or syndrome 0
              neoplasm 0
                neoplasm of thorax 0
                  breast neoplasm 0
                    breast cancer 0
                      breast carcinoma 0
                        Breast Carcinoma by Gene Expression Profile 0
                          HER2 negative breast carcinoma 0
                            triple-negative breast cancer 0
                              basal-like breast carcinoma 0
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