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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Radiation Pneumonitis
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Accession:DOID:9008604 term browser browse the term
Definition:Inflammation of the lung due to harmful effects of ionizing or non-ionizing radiation.
Synonyms:exact_synonym: Radiation Fibrosis;   Radiation Pneumonia;   Radiation Pneumonias;   Radiation Pneumonitides
 primary_id: MESH:D017564
 xref: EFO:1001411


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Radiation Pneumonitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase ISO RGD PMID:1886988 RGD:4890434 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139 		JBrowse link
G Atm ataxia telangiectasia mutated susceptibility ISO associated with lung cancer;DNA:SNPs:promoter:���111G>A,126713G>A (rs189037, s373759) (human) RGD PMID:20171797 RGD:150340755 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G C3 complement component 3 ISO Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G C4bp complement component 4 binding protein ISO Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chr 1:130,562,510...130,589,365
Ensembl chr 1:130,562,510...130,589,369 		JBrowse link
G Cblb Casitas B-lineage lymphoma b susceptibility ISO associated with lung non-small cell carcinoma; DNA:SNP,haplotype: :rs2305035(human) RGD PMID:26732495 RGD:150540334 NCBI chr16:51,851,593...52,028,410
Ensembl chr16:51,851,588...52,028,411 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 ISO mRNA, protein:increased expression:lung, alveolar macrophage RGD PMID:15293604 RGD:4145517 NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 ISO mRNA, protein:increased expression:lung, alveolar macrophage RGD PMID:15293604 RGD:4145517 NCBI chr 8:95,472,312...95,478,016
Ensembl chr 8:95,472,218...95,478,327 		JBrowse link
G Il13 interleukin 13 susceptibility ISO associated with carcinoma, non-small-cell lung; DNA:SNPs: :rs20541, rs180925 (human) RGD PMID:20811626 RGD:5131286 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il1a interleukin 1 alpha susceptibility ISO associated with carcinoma, non-small-cell lung: DNA:SNPs: :rs1800587,rs17561(human) RGD PMID:20811626 RGD:5131286 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) susceptibility ISO associated with carcinoma, non-small-cell lung; DNA:SNP: :rs755622(human) RGD PMID:20811626 RGD:5131286 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell susceptibility ISO associated with carcinoma, non-small-cell lung;DNA:SNP:cds:c.894G>T rs1799983 (human) RGD PMID:20811626 RGD:5131286 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Sftpd surfactant associated protein D susceptibility ISO RGD PMID:20459699 RGD:4143486 NCBI chr14:40,894,169...40,907,155
Ensembl chr14:40,894,171...40,907,106 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 susceptibility ISO protein:increased expression:blood
DNA:SNP:exon:869T>C (rs1982073) (human)		 RGD PMID:19943923 PMID:18411002 PMID:19380441 RGD:4145121, RGD:4145278, RGD:4145136 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tnf tumor necrosis factor susceptibility ISO associated with carcinoma, non-small-cell lung: DNA:SNPs: :rs1799724(human) RGD PMID:20811626 RGD:5131286 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IMP RGD PMID:18347190 RGD:5131153 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Vtn vitronectin ISO Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chr11:78,389,946...78,393,151
Ensembl chr11:78,389,917...78,393,150 		JBrowse link
G Zp3r zona pellucida 3 receptor ISO Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chr 1:130,474,847...130,557,371
Ensembl chr 1:130,504,450...130,557,358 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16271
    Wounds and Injuries 1004
      Radiation Injuries 82
        Radiation Pneumonitis 17
Path 2
Term Annotations click to browse term
  disease 16271
    disease of anatomical entity 15862
      respiratory system disease 5129
        lower respiratory tract disease 2353
          lung disease 2314
            interstitial lung disease 562
              Radiation Pneumonitis 17
paths to the root