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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Radiation Pneumonitis
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Accession:DOID:9008604 term browser browse the term
Definition:Inflammation of the lung due to harmful effects of ionizing or non-ionizing radiation.
Synonyms:exact_synonym: Radiation Fibrosis;   Radiation Pneumonia;   Radiation Pneumonias;   Radiation Pneumonitides
 primary_id: MESH:D017564
 xref: EFO:1001411



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Radiation Pneumonitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:1886988 RGD:4890434 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119
JBrowse link
G ATM ATM serine/threonine kinase susceptibility IAGP associated with lung cancer;DNA:SNPs:promoter:���111G>A,126713G>A (rs189037, s373759) (human) RGD PMID:20171797 RGD:150340755 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102
JBrowse link
G C3 complement C3 IEP Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G C4BPA complement component 4 binding protein alpha IEP Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chr 1:207,104,233...207,144,972
Ensembl chr 1:207,104,233...207,144,972
JBrowse link
G CBLB Cbl proto-oncogene B susceptibility IAGP associated with lung non-small cell carcinoma; DNA:SNP,haplotype: :rs2305035(human) RGD PMID:26732495 RGD:150540334 NCBI chr 3:105,655,461...105,869,449
Ensembl chr 3:105,655,461...105,869,552
JBrowse link
G CCL17 C-C motif chemokine ligand 17 ISO mRNA, protein:increased expression:lung, alveolar macrophage RGD PMID:15293604 RGD:4145517 NCBI chr16:57,396,093...57,416,063
Ensembl chr16:57,404,767...57,416,063
JBrowse link
G CCL22 C-C motif chemokine ligand 22 ISO mRNA, protein:increased expression:lung, alveolar macrophage RGD PMID:15293604 RGD:4145517 NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189
JBrowse link
G IL13 interleukin 13 susceptibility IAGP associated with carcinoma, non-small-cell lung; DNA:SNPs: :rs20541, rs180925 (human) RGD PMID:20811626 RGD:5131286 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL1A interleukin 1 alpha susceptibility IAGP associated with carcinoma, non-small-cell lung: DNA:SNPs: :rs1800587,rs17561(human) RGD PMID:20811626 RGD:5131286 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G MIF macrophage migration inhibitory factor susceptibility IAGP associated with carcinoma, non-small-cell lung; DNA:SNP: :rs755622(human) RGD PMID:20811626 RGD:5131286 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility IAGP associated with carcinoma, non-small-cell lung;DNA:SNP:cds:c.894G>T rs1799983 (human) RGD PMID:20811626 RGD:5131286 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G SFTPD surfactant protein D susceptibility IEP RGD PMID:20459699 RGD:4143486 NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614
JBrowse link
G TGFB1 transforming growth factor beta 1 susceptibility IEP
ISO
IAGP
protein:increased expression:blood
DNA:SNP:exon:869T>C (rs1982073) (human)
RGD PMID:19943923 PMID:18411002 PMID:19380441 RGD:4145121, RGD:4145278, RGD:4145136 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TNF tumor necrosis factor susceptibility IAGP associated with carcinoma, non-small-cell lung: DNA:SNPs: :rs1799724(human) RGD PMID:20811626 RGD:5131286 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO RGD PMID:18347190 RGD:5131153 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
JBrowse link
G VTN vitronectin IEP Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chr17:28,367,284...28,370,307
Ensembl chr17:28,367,284...28,373,091
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 121159
    Wounds and Injuries 1676
      Radiation Injuries 89
        Radiation Pneumonitis 16
Path 2
Term Annotations click to browse term
  disease 121159
    disease of anatomical entity 111930
      respiratory system disease 19528
        lower respiratory tract disease 5772
          lung disease 5711
            interstitial lung disease 755
              Radiation Pneumonitis 16
paths to the root