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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Radiation Pneumonitis
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Accession:DOID:9008604 term browser browse the term
Definition:Inflammation of the lung due to harmful effects of ionizing or non-ionizing radiation.
Synonyms:exact_synonym: Radiation Fibrosis;   Radiation Pneumonia;   Radiation Pneumonias;   Radiation Pneumonitides
 primary_id: MESH:D017564
 xref: EFO:1001411


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Radiation Pneumonitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:1886988 RGD:4890434 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331
JBrowse link
G ATM ATM serine/threonine kinase susceptibility ISO associated with lung cancer;DNA:SNPs:promoter:���111G>A,126713G>A (rs189037, s373759) (human) RGD PMID:20171797 RGD:150340755 NCBI chr 1:99,653,208...99,786,889
Ensembl chr 1:99,653,139...99,791,520
JBrowse link
G C3 complement C3 ISO Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chr 6:6,250,422...6,289,264 JBrowse link
G C4BPA complement component 4 binding protein alpha ISO Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chr25:22,169,355...22,254,331 JBrowse link
G CBLB Cbl proto-oncogene B susceptibility ISO associated with lung non-small cell carcinoma; DNA:SNP,haplotype: :rs2305035(human) RGD PMID:26732495 RGD:150540334 NCBI chr22:74,961,831...75,181,307
Ensembl chr22:74,961,859...75,178,548
JBrowse link
G CCL17 C-C motif chemokine ligand 17 ISO mRNA, protein:increased expression:lung, alveolar macrophage RGD PMID:15293604 RGD:4145517 NCBI chr 5:43,343,525...43,350,096
Ensembl chr 5:43,346,329...43,348,599
JBrowse link
G IL13 interleukin 13 susceptibility ISO associated with carcinoma, non-small-cell lung; DNA:SNPs: :rs20541, rs180925 (human) RGD PMID:20811626 RGD:5131286 NCBI chr23:35,475,762...35,479,419
Ensembl chr23:35,476,490...35,478,869
JBrowse link
G IL1A interleukin 1 alpha susceptibility ISO associated with carcinoma, non-small-cell lung: DNA:SNPs: :rs1800587,rs17561(human) RGD PMID:20811626 RGD:5131286 NCBI chr14:15,789,710...15,801,938
Ensembl chr14:15,789,013...15,796,611
JBrowse link
G LOC103233057 C-C motif chemokine 22 ISO mRNA, protein:increased expression:lung, alveolar macrophage RGD PMID:15293604 RGD:4145517 NCBI chr 5:43,297,206...43,305,662
Ensembl chr 5:43,297,897...43,305,642
JBrowse link
G MIF macrophage migration inhibitory factor susceptibility ISO associated with carcinoma, non-small-cell lung; DNA:SNP: :rs755622(human) RGD PMID:20811626 RGD:5131286 NCBI chr19:7,000,837...7,001,700
Ensembl chr19:7,000,793...7,001,757
JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility ISO associated with carcinoma, non-small-cell lung;DNA:SNP:cds:c.894G>T rs1799983 (human) RGD PMID:20811626 RGD:5131286 NCBI chr21:119,174,829...119,196,840 JBrowse link
G SFTPD surfactant protein D susceptibility ISO RGD PMID:20459699 RGD:4143486 NCBI chr 9:51,809,241...51,820,974
Ensembl chr 9:51,811,052...51,820,650
JBrowse link
G TGFB1 transforming growth factor beta 1 susceptibility ISO DNA:SNP:exon:869T>C (rs1982073) (human)
protein:increased expression:blood
RGD PMID:18411002 PMID:19380441 PMID:19943923 RGD:4145121 RGD:4145136 RGD:4145278 NCBI chr 6:35,651,583...35,674,387
Ensembl chr 6:35,648,677...35,674,365
JBrowse link
G TNF tumor necrosis factor susceptibility ISO associated with carcinoma, non-small-cell lung: DNA:SNPs: :rs1799724(human) RGD PMID:20811626 RGD:5131286
G TNFRSF1A TNF receptor superfamily member 1A ISO RGD PMID:18347190 RGD:5131153 NCBI chr11:6,364,544...6,378,880
Ensembl chr11:6,364,330...6,378,902
JBrowse link
G VTN vitronectin ISO Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chr16:22,133,903...22,138,077
Ensembl chr16:22,133,138...22,136,815
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15417
    Wounds and Injuries 941
      Radiation Injuries 76
        Radiation Pneumonitis 16
Path 2
Term Annotations click to browse term
  disease 15417
    disease of anatomical entity 15080
      respiratory system disease 4789
        lower respiratory tract disease 2152
          lung disease 2112
            interstitial lung disease 514
              Radiation Pneumonitis 16
paths to the root