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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Radiation Pneumonitis
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Accession:DOID:9008604 term browser browse the term
Definition:Inflammation of the lung due to harmful effects of ionizing or non-ionizing radiation.
Synonyms:exact_synonym: Radiation Fibrosis;   Radiation Pneumonia;   Radiation Pneumonias;   Radiation Pneumonitides
 primary_id: MESH:D017564
 xref: EFO:1001411


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Radiation Pneumonitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase ISO RGD PMID:1886988 RGD:4890434 NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909
JBrowse link
G Atm ATM serine/threonine kinase susceptibility ISO associated with lung cancer;DNA:SNPs:promoter:���111G>A,126713G>A (rs189037, s373759) (human) RGD PMID:20171797 RGD:150340755 NCBI chrNW_004955412:10,422,753...10,531,406
Ensembl chrNW_004955412:10,426,135...10,530,545
JBrowse link
G C3 complement C3 ISO Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697
JBrowse link
G C4bpa complement component 4 binding protein alpha ISO Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chrNW_004955406:42,613,659...42,641,918
Ensembl chrNW_004955406:42,613,607...42,641,670
JBrowse link
G Cblb Cbl proto-oncogene B susceptibility ISO associated with lung non-small cell carcinoma; DNA:SNP,haplotype: :rs2305035(human) RGD PMID:26732495 RGD:150540334 NCBI chrNW_004955427:6,601,651...6,812,896
Ensembl chrNW_004955427:6,604,820...6,812,882
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 ISO mRNA, protein:increased expression:lung, alveolar macrophage RGD PMID:15293604 RGD:4145517 NCBI chrNW_004955433:15,052,616...15,054,732
Ensembl chrNW_004955433:15,053,061...15,054,572
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 ISO mRNA, protein:increased expression:lung, alveolar macrophage RGD PMID:15293604 RGD:4145517 NCBI chrNW_004955433:15,002,001...15,007,324
Ensembl chrNW_004955433:15,001,930...15,008,032
JBrowse link
G Il13 interleukin 13 susceptibility ISO associated with carcinoma, non-small-cell lung; DNA:SNPs: :rs20541, rs180925 (human) RGD PMID:20811626 RGD:5131286 NCBI chrNW_004955408:4,046,406...4,049,795 JBrowse link
G Il1a interleukin 1 alpha susceptibility ISO associated with carcinoma, non-small-cell lung: DNA:SNPs: :rs1800587,rs17561(human) RGD PMID:20811626 RGD:5131286 NCBI chrNW_004955470:1,527,710...1,538,418
Ensembl chrNW_004955470:1,527,674...1,538,466
JBrowse link
G Mif macrophage migration inhibitory factor susceptibility ISO associated with carcinoma, non-small-cell lung; DNA:SNP: :rs755622(human) RGD PMID:20811626 RGD:5131286 NCBI chrNW_004955455:8,367,566...8,368,460
Ensembl chrNW_004955455:8,367,566...8,368,460
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO associated with carcinoma, non-small-cell lung;DNA:SNP:cds:c.894G>T rs1799983 (human) RGD PMID:20811626 RGD:5131286 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814
JBrowse link
G Sftpd surfactant protein D susceptibility ISO RGD PMID:20459699 RGD:4143486 NCBI chrNW_004955510:213,468...226,096
Ensembl chrNW_004955510:213,438...225,896
JBrowse link
G Tgfb1 transforming growth factor beta 1 susceptibility ISO DNA:SNP:exon:869T>C (rs1982073) (human)
protein:increased expression:blood
RGD PMID:18411002 PMID:19380441 PMID:19943923 RGD:4145121 RGD:4145136 RGD:4145278 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441
JBrowse link
G Tnf tumor necrosis factor susceptibility ISO associated with carcinoma, non-small-cell lung: DNA:SNPs: :rs1799724(human) RGD PMID:20811626 RGD:5131286 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO RGD PMID:18347190 RGD:5131153 NCBI chrNW_004955413:3,982,670...3,996,320
Ensembl chrNW_004955413:3,981,400...3,996,021
JBrowse link
G Vtn vitronectin ISO Protein: increased expression: plasma RGD PMID:20510197 RGD:5129484 NCBI chrNW_004955481:4,765,078...4,768,027
Ensembl chrNW_004955481:4,765,193...4,771,019
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14337
    Wounds and Injuries 891
      Radiation Injuries 74
        Radiation Pneumonitis 16
Path 2
Term Annotations click to browse term
  disease 14337
    disease of anatomical entity 14030
      respiratory system disease 4555
        lower respiratory tract disease 2037
          lung disease 1999
            interstitial lung disease 480
              Radiation Pneumonitis 16
paths to the root