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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Bacterial Lung Diseases
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Accession:DOID:9008559 term browser browse the term
Definition:Pulmonary diseases caused by bacterial infections.
Synonyms:primary_id: RDO:9002453


show annotations for term's descendants           Sort by:
Bacterial Lung Diseases term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl15 C-X-C motif chemokine ligand 15 severity ISO protein:increased expression:nasal mucus (human) RGD PMID:24211414 RGD:40925940 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Marco macrophage receptor with collagenous structure disease_progression IMP association with Cryptococcal neoformans infection. RGD PMID:28298522 RGD:41412191 NCBI chr 1:120,402,267...120,432,753
Ensembl chr 1:120,402,267...120,432,753 		JBrowse link
aspiration pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO associated with Cerebrovascular Accident RGD PMID:14990394 RGD:4140926 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO RGD PMID:19515386 RGD:4891456 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO RGD PMID:19515386 RGD:4891456 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Edn1 endothelin 1 ISO protein:increased secretion:plasma (rat) RGD PMID:19262391 RGD:4145069 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Il1a interleukin 1 alpha ISO protein:increased expression:Bronchoalveolar Lavage Fluid RGD PMID:18042282 RGD:4142854 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible ISO CTD Direct Evidence: marker/mechanism CTD PMID:15607125 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:Bronchoalveolar Lavage Fluid RGD PMID:18042282 RGD:4142854 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
bacterial pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP-binding cassette, sub-family C member 1 IMP RGD PMID:11238654 RGD:5128828 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Ace2 angiotensin converting enzyme 2 IEP associated with Pseudomonas Infections;mRNA, protein:altered expression, altered activity:lung (mouse) RGD PMID:31645418 RGD:40818279 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416 		JBrowse link
G Ager advanced glycosylation end product-specific receptor severity IAGP RGD PMID:21629785 RGD:6767559 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G C3 complement component 3 IMP RGD PMID:16014897 RGD:5129508 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G C3ar1 complement component 3a receptor 1 IMP RGD PMID:16461429 RGD:5129690 NCBI chr 6:122,824,099...122,833,116
Ensembl chr 6:122,824,097...122,833,120 		JBrowse link
G Cat catalase ISO RGD PMID:19842849 RGD:5130748 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 IEP mRNA, protein:increased expression:lung RGD PMID:20176793 RGD:5130918 NCBI chr 4:42,754,525...42,756,558
Ensembl chr 4:42,754,525...42,756,577 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IMP RGD PMID:20042590 RGD:4891443 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 IEP RGD PMID:20483921 RGD:5130905 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 IMP RGD PMID:20042590 RGD:4891443 NCBI chr 9:123,901,954...123,913,594
Ensembl chr 9:123,901,987...123,913,594 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 IMP RGD PMID:20176793 RGD:5130918 NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903 		JBrowse link
G Cd14 CD14 antigen IMP RGD PMID:16210672 RGD:4144197 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Cd40 CD40 antigen IEP RGD PMID:20102413 RGD:5132268 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cd80 CD80 antigen IEP RGD PMID:20949109 RGD:4892562 NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697 		JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase IEP RGD PMID:18643924 RGD:5133701 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919 		JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) disease_progression
treatment		 ISO associated with Peritonitis; RGD PMID:21373266 PMID:12352049 RGD:5133733, RGD:11039437 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455 		JBrowse link
G Csf3r colony stimulating factor 3 receptor disease_progression IMP RGD PMID:17185469 RGD:5133739 NCBI chr 4:125,917,241...125,938,233
Ensembl chr 4:125,918,343...125,938,233 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP
ISO		 RGD PMID:21723409 PMID:11052817 RGD:5135062, RGD:5135234 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 severity IMP
IEP		 RGD PMID:16299319 PMID:15618188 RGD:5135458, RGD:5135459 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748 		JBrowse link
G Cxcl11 chemokine (C-X-C motif) ligand 11 IEP RGD PMID:15618188 RGD:5135459 NCBI chr 5:92,507,403...92,511,155
Ensembl chr 5:92,507,403...92,513,344 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 severity IEP
ISO		 RGD PMID:21723409 PMID:11052817 PMID:19239431 RGD:5135062, RGD:5135234, RGD:5135065 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 ISO RGD PMID:11052817 RGD:5135234 NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459 		JBrowse link
G Cxcl5 C-X-C motif chemokine ligand 5 IEP RGD PMID:19846873 RGD:4145490 NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 IEP RGD PMID:15618188 RGD:5135459 NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 IMP RGD PMID:15618188 RGD:5135459 NCBI chr  X:100,775,141...100,777,753
Ensembl chr  X:100,775,141...100,777,875 		JBrowse link
G Cyp2j6 cytochrome P450, family 2, subfamily j, polypeptide 6 ISO protein:decreased expression:lung RGD PMID:14766666 RGD:1625385 NCBI chr 4:96,404,375...96,449,835
Ensembl chr 4:96,404,375...96,441,898 		JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 ISO protein:decreased expression:lung RGD PMID:14766666 RGD:1625385 NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815 		JBrowse link
G Defb3 defensin beta 3 ISO protein:increased expression:plasma RGD PMID:10213993 RGD:4892266 NCBI chr 8:19,343,377...19,345,355
Ensembl chr 8:19,343,376...19,345,307 		JBrowse link
G Defb4 defensin beta 4 ISO protein:increased expression:plasma RGD PMID:10213993 RGD:4892266 NCBI chr 8:19,248,720...19,251,563
Ensembl chr 8:19,248,722...19,251,561 		JBrowse link
G F2 coagulation factor II ISO RGD PMID:21897338 RGD:6893486 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III IMP RGD PMID:17975174 RGD:5129707 NCBI chr 1:170,878,738...170,893,477
Ensembl chr 1:170,878,743...170,892,504 		JBrowse link
G Foxp3 forkhead box P3 severity IEP RGD PMID:25398094 RGD:38501102 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Gp1ba glycoprotein 1b, alpha polypeptide exacerbates IMP associated with Escherichia Coli Infections RGD PMID:27845343 RGD:42722624 NCBI chr11:70,529,928...70,534,812
Ensembl chr11:70,529,948...70,532,862 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO mRNA:decreased expression:polymorphonuclear leukocyte RGD PMID:24465168 RGD:126848796 NCBI chr19:4,336,029...4,356,356
Ensembl chr19:4,336,029...4,356,250 		JBrowse link
G Hc hemolytic complement IMP RGD PMID:17975174 RGD:5129707 NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP protein:increased expression:lung (mouse) RGD PMID:19846873 RGD:4145490 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Ifnar1 interferon (alpha and beta) receptor 1 severity IMP RGD PMID:19487810 RGD:5490274 NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329 		JBrowse link
G Ifng interferon gamma severity IEP RGD PMID:25398094 RGD:38501102 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il10 interleukin 10 severity IEP RGD PMID:25398094 RGD:38501102 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il15 interleukin 15 IMP RGD PMID:17911627 RGD:5000754 NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851 		JBrowse link
G Il17a interleukin 17A severity IMP
IEP		 RGD PMID:18802100 PMID:25398094 RGD:4889153, RGD:38501102 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720 		JBrowse link
G Il18 interleukin 18 IMP RGD PMID:17664259 RGD:4889913 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il1b interleukin 1 beta severity
treatment		 IMP
IEP
ISO		 associated with Agranulocytosis RGD PMID:18596024 PMID:25398094 PMID:7546648 RGD:4143205, RGD:38501102, RGD:10755357 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 treatment IMP
ISO		 associated with Sepsis
associated with Acinetobacter infectious disease		 RGD PMID:20959556 PMID:29508184 RGD:5144223, RGD:40818077 NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575 		JBrowse link
G Il1rn interleukin 1 receptor antagonist IMP RGD PMID:18322242 PMID:18596024 RGD:4143206, RGD:4143205 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il22 interleukin 22 IMP RGD PMID:21178015 RGD:5147404 NCBI chr10:118,040,456...118,045,952
Ensembl chr10:118,040,847...118,045,952 		JBrowse link
G Il6 interleukin 6 severity IEP RGD PMID:25398094 RGD:38501102 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 IMP RGD PMID:28120642 PMID:20439918 RGD:34888234, RGD:36049799 NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035 		JBrowse link
G Irf1 interferon regulatory factor 1 IMP RGD PMID:11854220 RGD:5128725 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200 		JBrowse link
G Irf3 interferon regulatory factor 3 IMP RGD PMID:20720199 RGD:4891951 NCBI chr 7:44,647,072...44,652,272
Ensembl chr 7:44,647,072...44,652,272 		JBrowse link
G Itgb3 integrin beta 3 ISO protein:increased expression:lung, neutrophil RGD PMID:15114484 RGD:4993468 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302 		JBrowse link
G Lep leptin IMP RGD PMID:11937559 RGD:5128871 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 severity IMP associated with Escherichia Coli Infections RGD PMID:22514650 RGD:150340681 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 ISO Legionella Pneumonia; DNA:mutations:5' utr, exon:multiple (human) RGD PMID:18641104 RGD:4889477 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087 		JBrowse link
G Mc1r melanocortin 1 receptor IMP RGD PMID:18304533 RGD:5687324 NCBI chr 8:124,133,839...124,137,483
Ensembl chr 8:124,133,846...124,137,483 		JBrowse link
G Mmp9 matrix metallopeptidase 9 IMP
ISO		 protein:increased expression:bronchoalveolar lavage fluid RGD PMID:17202364 PMID:19535150 RGD:5130727, RGD:5129533 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Mpo myeloperoxidase ISO protein:increased activity:bronchoalveolar lavage Fluid: RGD PMID:11269653 RGD:5130992 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 IMP RGD PMID:19360122 RGD:5131449 NCBI chr 6:54,900,927...54,949,655
Ensembl chr 6:54,900,934...54,949,597 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IMP RGD PMID:19360122 RGD:5131449 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Pdpn podoplanin ISO protein:increased expression:lung RGD PMID:7864138 RGD:2292375 NCBI chr 4:142,993,979...143,026,134
Ensembl chr 4:142,994,001...143,026,134 		JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 ISO protein:decreased expression:lung RGD PMID:12524254 RGD:724645 NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454 		JBrowse link
G Pgf placental growth factor IEP protein:increased expression:plasma RGD PMID:16702604 RGD:6483601 NCBI chr12:85,213,413...85,224,087
Ensembl chr12:85,213,409...85,224,564 		JBrowse link
G Pten phosphatase and tensin homolog ameliorates IMP myeloid knockout RGD PMID:21527775 RGD:127285594 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 ameliorates IMP RGD PMID:28387756 RGD:127229944 NCBI chr14:56,022,452...56,026,314
Ensembl chr14:56,022,452...56,026,322 		JBrowse link
G Rorc RAR-related orphan receptor gamma severity IEP RGD PMID:25398094 RGD:38501102 NCBI chr 3:94,280,106...94,305,583
Ensembl chr 3:94,280,101...94,305,583 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 severity IMP RGD PMID:17032919 RGD:4144840 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Sftpa1 surfactant associated protein A1 ISO protein:increased expression:lung RGD PMID:12169586 RGD:4143464 NCBI chr14:40,853,745...40,858,330
Ensembl chr14:40,853,739...40,858,409 		JBrowse link
G Sftpb surfactant associated protein B ISO associated with Cystic Fibrosis;protein:increased expression:lung RGD PMID:15271694 PMID:12169586 RGD:4143403, RGD:4143464 NCBI chr 6:72,281,594...72,291,354
Ensembl chr 6:72,281,594...72,291,354 		JBrowse link
G Sftpc surfactant associated protein C IMP
ISO		 RGD PMID:18566429 PMID:12169586 RGD:4144114, RGD:4143464 NCBI chr14:70,758,381...70,761,521
Ensembl chr14:70,758,389...70,761,521 		JBrowse link
G Sftpd surfactant associated protein D ISO associated with Cystic Fibrosis;protein:decreased expression:lung
protein:increased expression:lung		 RGD PMID:15271694 PMID:12169586 RGD:4143403, RGD:4143464 NCBI chr14:40,894,169...40,907,155
Ensembl chr14:40,894,171...40,907,106 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 IMP RGD PMID:18192501 RGD:6892945 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 severity IEP RGD PMID:25398094 RGD:38501102 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tlr2 toll-like receptor 2 IMP
ISO		 RGD PMID:18768871 PMID:19844782 RGD:4145337, RGD:4889533 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tlr4 toll-like receptor 4 IMP RGD PMID:16210672 PMID:20650991 RGD:4144197, RGD:4144172 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tlr5 toll-like receptor 5 IMP RGD PMID:19801452 RGD:5129503 NCBI chr 1:182,782,317...182,804,010
Ensembl chr 1:182,782,353...182,804,010 		JBrowse link
G Tlr6 toll-like receptor 6 ISO RGD PMID:19844782 RGD:4889533 NCBI chr 5:65,109,373...65,128,387
Ensembl chr 5:65,109,374...65,117,440 		JBrowse link
G Tlr9 toll-like receptor 9 IMP RGD PMID:20360853 RGD:5130719 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082 		JBrowse link
G Tnf tumor necrosis factor disease_progression
treatment
severity		 ISO
IMP		 associated with Agranulocytosis RGD PMID:10650487 PMID:7546648 PMID:9310939 PMID:12958055 RGD:4143476, RGD:10755357, RGD:10450564, RGD:10449451 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IEP protein:increased expression:serum (mouse) RGD PMID:19842848 RGD:5131429 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b IEP protein:increased expression:serum (mouse) RGD PMID:19842848 RGD:5131429 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 severity
ameliorates		 ISO RGD PMID:24465168 PMID:16960786 PMID:22996209 RGD:126848796, RGD:127229902, RGD:126925987 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A IMP associated with Pseudomonas Infections RGD PMID:29695841 RGD:39938967 NCBI chr 4:125,012,207...125,021,674
Ensembl chr 4:125,012,216...125,021,633 		JBrowse link
Chlamydia pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 antigen IEP mRNA:increased expression:lung RGD PMID:26378990 RGD:41412180 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495 		JBrowse link
G Pdcd1 programmed cell death 1 IEP mRNA:increased expression:lung RGD PMID:26378990 RGD:41412180 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta severity IMP RGD PMID:29893841 RGD:40890270 NCBI chr 4:149,733,625...149,787,023
Ensembl chr 4:149,733,625...149,787,028 		JBrowse link
Klebsiella pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl15 C-X-C motif chemokine ligand 15 IMP RGD PMID:11207292 RGD:38549344 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Il23a interleukin 23, alpha subunit p19 severity IMP RGD PMID:16157683 RGD:39457940 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 severity IMP
IEP		 mRNA:increased expression:lung (mouse) RGD PMID:22729155 PMID:20864681 RGD:35316077, RGD:36049798 NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035 		JBrowse link
G Lcn2 lipocalin 2 exacerbates
ameliorates		 IMP
IGI
IEP		 protein:increased expression:lung
protein:increased expression:serum		 RGD PMID:29633303 PMID:19342674 PMID:19342674 PMID:19342674 PMID:25234944 More... RGD:126725082, RGD:126725085, RGD:126725085, RGD:126725085, RGD:126725084, RGD:126725084 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Plac8 placenta-specific 8 severity IMP RGD PMID:17404296 RGD:40924563 NCBI chr 5:100,699,455...100,720,119
Ensembl chr 5:100,701,591...100,720,111 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 disease_progression IMP RGD PMID:24396044 RGD:126925976 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
Legionnaires' disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase ISO protein:increased expression:serum RGD PMID:9255891 RGD:5128857 NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IMP RGD PMID:16113250 RGD:4891897 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP mRNA, protein:increased expression:lung RGD PMID:11254553 RGD:5135252 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IEP mRNA, protein:increased expression:lung RGD PMID:11254553 RGD:5135252 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cxcl5 C-X-C motif chemokine ligand 5 IEP mRNA, protein:increased expression:lung RGD PMID:11254553 RGD:5135252 NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 IMP RGD PMID:11254553 RGD:5135252 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405 		JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: therapeutic CTD PMID:11349020 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il18 interleukin 18 IDA RGD PMID:11083766 RGD:4889865 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 susceptibility ISO RGD PMID:19073229 RGD:12910934 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 IMP RGD PMID:20685341 RGD:5131443 NCBI chr 6:54,900,927...54,949,655
Ensembl chr 6:54,900,934...54,949,597 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IMP RGD PMID:20685341 RGD:5131443 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Tlr5 toll-like receptor 5 susceptibility ISO
IMP		 DNA:nonsense mutation:cds:p.R392X (human)
ClinVar Annotator: match by term: Legionnaire disease, susceptibility to
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD
RGD		 PMID:14623910 PMID:16027372 PMID:23447684 PMID:14623910 PMID:17982089 RGD:5129477, RGD:5129510 NCBI chr 1:182,782,317...182,804,010
Ensembl chr 1:182,782,353...182,804,010 		JBrowse link
G Tlr9 toll-like receptor 9 IMP RGD PMID:18426877 RGD:5130707 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IMP RGD PMID:18838275 RGD:5131445 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b IMP RGD PMID:18838275 RGD:5131445 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440 		JBrowse link
Mycoplasma pneumoniae pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase ISO protein:increased expression:serum RGD PMID:9255891 RGD:5128857 NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159 		JBrowse link
G Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr11:69,490,554...69,496,786
Ensembl chr11:69,490,562...69,496,768 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 IEP RGD PMID:16988274 RGD:4892091 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 IEP protein:increased secretion:lung, secretion (mouse) RGD PMID:18717637 RGD:4891914 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Ccl8 C-C motif chemokine ligand 8 IEP RGD PMID:16988274 RGD:4892091 NCBI chr11:82,006,011...82,007,625
Ensembl chr11:82,006,011...82,007,625 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEP protein:increased expression:lung, T-helper cell (mouse) RGD PMID:16988274 RGD:4892091 NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736 		JBrowse link
G Clec5a C-type lectin domain family 5, member a severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr 6:40,551,832...40,562,739
Ensembl chr 6:40,551,828...40,562,755 		JBrowse link
G Col3a1 collagen, type III, alpha 1 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866 		JBrowse link
G Col6a1 collagen, type VI, alpha 1 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr10:76,544,626...76,561,869
Ensembl chr10:76,544,626...76,562,002 		JBrowse link
G Col6a2 collagen, type VI, alpha 2 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr10:76,431,590...76,459,464
Ensembl chr10:76,431,596...76,459,464 		JBrowse link
G Crp C-reactive protein, pentraxin-related ISO RGD PMID:21426633 RGD:5131292 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Dnase1l3 deoxyribonuclease 1-like 3 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr14:14,475,014...14,504,586
Ensembl chr14:14,475,200...14,505,240 		JBrowse link
G Fcer2a Fc receptor, IgE, low affinity II, alpha polypeptide severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr 8:3,730,280...3,744,174
Ensembl chr 8:3,731,737...3,744,175 		JBrowse link
G Flt1 FMS-like tyrosine kinase 1 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821 		JBrowse link
G Galc galactosylceramidase ISO
IEP		 associated with Guillain-Barre syndrome; protein:increased expression:serum (human)
associated with Guillain-Barre syndrome; protein:increased expression:Cerebrospinal fluid, serum (human)
protein:increased expression:serum (mouse)		 RGD PMID:27490360 PMID:29301655 PMID:30396892 PMID:30396892 PMID:12225900 RGD:38599168, RGD:38599172, RGD:38599171, RGD:38599171, RGD:38599169 NCBI chr12:98,168,543...98,226,565
Ensembl chr12:98,168,553...98,225,718 		JBrowse link
G Hdc histidine decarboxylase IEP RGD PMID:17158962 RGD:5143920 NCBI chr 2:126,435,579...126,465,942
Ensembl chr 2:126,435,587...126,461,219 		JBrowse link
G Htra3 HtrA serine peptidase 3 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr 5:35,809,370...35,837,157
Ensembl chr 5:35,809,367...35,837,126 		JBrowse link
G Ifng interferon gamma IEP mRNA:increased expression:lung: RGD PMID:7935058 RGD:10755754 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il13 interleukin 13 ISO protein:increased expression:serum RGD PMID:20416219 RGD:4145765 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il22ra2 interleukin 22 receptor, alpha 2 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr10:19,497,776...19,510,429
Ensembl chr10:19,497,746...19,510,429 		JBrowse link
G Inhba inhibin beta-A severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr13:16,178,841...16,206,194
Ensembl chr13:16,186,436...16,206,206 		JBrowse link
G Ms4a1 membrane-spanning 4-domains, subfamily A, member 1 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr19:11,227,043...11,243,513
Ensembl chr19:11,227,039...11,243,605 		JBrowse link
G Pld4 phospholipase D family member 4 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr12:112,727,089...112,735,420
Ensembl chr12:112,727,089...112,735,424 		JBrowse link
G Spib Spi-B transcription factor (Spi-1/PU.1 related) severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr 7:44,175,419...44,181,511
Ensembl chr 7:44,175,417...44,181,495 		JBrowse link
G Tcf7 transcription factor 7, T cell specific severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr11:52,137,347...52,174,211
Ensembl chr11:52,143,198...52,174,158 		JBrowse link
G Tcl1 T cell lymphoma breakpoint 1 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr12:105,183,012...105,188,996
Ensembl chr12:105,183,009...105,189,052 		JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:serum RGD PMID:20416219 RGD:4145765 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf13c tumor necrosis factor receptor superfamily, member 13c severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr15:82,105,943...82,108,581
Ensembl chr15:82,105,944...82,108,570 		JBrowse link
Pneumococcal Pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase IMP RGD PMID:26456931 RGD:11098923 NCBI chr 6:122,530,768...122,541,139
Ensembl chr 6:122,530,760...122,541,139 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase IMP RGD PMID:20231413 RGD:4890435 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139 		JBrowse link
G Btk Bruton agammaglobulinemia tyrosine kinase ameliorates IMP RGD PMID:30646846 RGD:124715470 NCBI chr  X:133,443,083...133,484,366
Ensembl chr  X:133,443,085...133,484,319 		JBrowse link
G C3 complement component 3 disease_progression IMP
ISO		 associated with Liver Cirrhosis, Experimental;protein:decreased expression:respiratory system fluid/secretion
protein:decreased expression:serum		 RGD PMID:15972516 PMID:17956621 PMID:20405 RGD:5129509, RGD:5129523, RGD:5130163 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 susceptibility IMP RGD PMID:16455992 RGD:4892130 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Cd14 CD14 antigen IMP RGD PMID:17185649 RGD:4144788 NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851 		JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:increased secretion:serum (human) RGD PMID:10515841 RGD:4892626 NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IMP RGD PMID:21774994 RGD:5147472 NCBI chr11:104,021,289...104,066,349
Ensembl chr11:104,023,681...104,066,349 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:21774994 RGD:5147472 NCBI chr 6:55,067,033...55,110,001
Ensembl chr 6:55,067,034...55,110,001 		JBrowse link
G Crp C-reactive protein, pentraxin-related disease_progression ISO RGD PMID:21281676 RGD:5131293 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP protein:increased expression:respiratory system fluid/secretion RGD PMID:20958976 RGD:5134957 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24894820 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 IEP protein:increased expression:lung RGD PMID:20381636 RGD:5135285 NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938 		JBrowse link
G Defb3 defensin beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24894820 NCBI chr 8:19,343,377...19,345,355
Ensembl chr 8:19,343,376...19,345,307 		JBrowse link
G Hc hemolytic complement severity IAGP RGD PMID:7814608 RGD:5130159 NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450 		JBrowse link
G Hmox1 heme oxygenase 1 IEP associated with influenza;protein:increased expression:lung RGD PMID:17348295 RGD:4145366 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hp haptoglobin ISO RGD PMID:19396720 RGD:5147385 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804 		JBrowse link
G Il15 interleukin 15 IEP protein:increased expression:alveolar macrophage, bronchial epithelial cell RGD PMID:17611121 RGD:5000755 NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851 		JBrowse link
G Il15ra interleukin 15 receptor, alpha chain IEP RGD PMID:17611121 RGD:5000755 NCBI chr 2:11,709,992...11,739,129
Ensembl chr 2:11,710,101...11,739,128 		JBrowse link
G Il17a interleukin 17A IDA RGD PMID:19995896 RGD:4888531 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720 		JBrowse link
G Il18 interleukin 18 IMP RGD PMID:15770015 RGD:4889960 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il6 interleukin 6 IDA RGD PMID:20643849 RGD:4143255 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Lep leptin IMP RGD PMID:17822444 RGD:5128869 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Lepr leptin receptor IMP RGD PMID:21148797 RGD:5128846 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24894820 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24894820 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Masp2 MBL associated serine protease 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12904520 NCBI chr 4:148,679,079...148,699,939
Ensembl chr 4:148,687,011...148,699,956 		JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 no_association ISO DNA:polymorphisms:5' utr, exon:multiple (human)
DNA:mutations:5' utr, exon:multiple (human)		 RGD PMID:12047967 PMID:18641104 RGD:4889478, RGD:4889477 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible IMP RGD PMID:17056580 RGD:4891950 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Pten phosphatase and tensin homolog ameliorates IMP myeloid knockout RGD PMID:20505137 RGD:127285597 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Sftpd surfactant associated protein D severity IMP RGD PMID:16255775 RGD:4143519 NCBI chr14:40,894,169...40,907,155
Ensembl chr14:40,894,171...40,907,106 		JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24894820 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 IMP RGD PMID:29263110 RGD:39128230 NCBI chr18:35,866,731...35,873,607
Ensembl chr18:35,866,732...35,873,607 		JBrowse link
G Tlr2 toll-like receptor 2 IMP RGD PMID:19956717 RGD:4145321 NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074 		JBrowse link
G Tnf tumor necrosis factor IMP
IEP		 associated with influenza;protein:increased expression:lung RGD PMID:9032201 PMID:17348295 RGD:4143479, RGD:4145366 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ameliorates IEP
IDA		 RGD PMID:24752755 PMID:19596984 RGD:126928121, RGD:127229903 NCBI chr17:48,539,763...48,553,955
Ensembl chr17:48,539,796...48,553,952 		JBrowse link
pneumonic tularemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ido1 indoleamine 2,3-dioxygenase 1 IMP RGD PMID:20385761 RGD:39938865 NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025 		JBrowse link
Staphylococcal Pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 thymoma viral proto-oncogene 1 treatment IMP RGD PMID:23613163 RGD:38676477 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Cd86 CD86 antigen IEP protein:decreased expression:spleen, plasmacytoid dendritic cell (mouse) RGD PMID:20949109 RGD:4892562 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443 		JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator IMP RGD PMID:28289144 RGD:36049750 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767 		JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) treatment ISO RGD PMID:10228098 RGD:11039478 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455 		JBrowse link
G Fn1 fibronectin 1 ISO RGD PMID:12065530 RGD:7205474 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359 		JBrowse link
G Ifnar1 interferon (alpha and beta) receptor 1 susceptibility IMP RGD PMID:19603548 RGD:5490273 NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329 		JBrowse link
G Il10 interleukin 10 IEP mRNA, protein:increased expression:lung RGD PMID:22940620 RGD:7364825 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il15 interleukin 15 IMP RGD PMID:18390740 RGD:4996474 NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851 		JBrowse link
G Il1b interleukin 1 beta IGI RGD PMID:20065029 RGD:4142828 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il33 interleukin 33 IEP mRNA:increased expression:lung: RGD PMID:28401938 RGD:40400699 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IMP RGD PMID:20493961 RGD:5131444 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IEP protein:increased expression:lung (mouse) RGD PMID:28663335 RGD:13432209 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 severity IEP
IMP		 mRNA:increased expression:lung
associated with influenza		 RGD PMID:31782850 PMID:31782850 RGD:39131288, RGD:39131288 NCBI chr 5:121,268,596...121,329,460
Ensembl chr 5:121,268,596...121,329,460 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 treatment IEP RGD PMID:25445964 RGD:127229910 NCBI chr14:56,022,452...56,026,314
Ensembl chr14:56,022,452...56,026,322 		JBrowse link
G Sftpb surfactant associated protein B ameliorates ISO RGD PMID:20007532 RGD:151667448 NCBI chr 6:72,281,594...72,291,354
Ensembl chr 6:72,281,594...72,291,354 		JBrowse link
Streptococcus pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ataxia telangiectasia mutated exacerbates IMP RGD PMID:27421701 RGD:126779562 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Btk Bruton agammaglobulinemia tyrosine kinase IMP RGD PMID:30873567 RGD:124715473 NCBI chr  X:133,443,083...133,484,366
Ensembl chr  X:133,443,085...133,484,319 		JBrowse link
G Cd209b CD209b antigen severity IMP RGD PMID:16134084 RGD:39938986 NCBI chr 8:3,967,655...3,976,841
Ensembl chr 8:3,967,655...3,976,844 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 IEP mRNA:increased expression:lung (mouse) RGD PMID:20385761 RGD:39938865 NCBI chr 8:25,074,148...25,086,987
Ensembl chr 8:25,074,152...25,087,025 		JBrowse link
G Ifng interferon gamma IEP protein:increased expression:lung,natural killer cell (mouse) RGD PMID:21887255 RGD:40818252 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il6 interleukin 6 IEP protein:increased expression:lung,natural killer cell (mouse) RGD PMID:21887255 RGD:40818252 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 severity IMP RGD PMID:22492852 RGD:35316076 NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035 		JBrowse link
G Itgb2 integrin beta 2 susceptibility IMP RGD PMID:11390487 RGD:127345090 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 IEP protein:increased expression:lung, natural killer cell (mouse) RGD PMID:21887255 RGD:40818252 NCBI chr 8:13,209,161...13,225,338
Ensembl chr 8:13,209,161...13,225,338 		JBrowse link
G Marco macrophage receptor with collagenous structure exacerbates IMP RGD PMID:15263032 RGD:41412189 NCBI chr 1:120,402,267...120,432,753
Ensembl chr 1:120,402,267...120,432,753 		JBrowse link
G Ncr1 natural cytotoxicity triggering receptor 1 severity IMP RGD PMID:21887255 RGD:40818252 NCBI chr 7:4,340,714...4,348,183
Ensembl chr 7:4,340,723...4,348,163 		JBrowse link
G Pdcd1 programmed cell death 1 treatment IMP RGD PMID:25624454 RGD:40818422 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta treatment IMP associated with immunodeficiency 14 RGD PMID:30093657 RGD:40890269 NCBI chr 4:149,733,625...149,787,023
Ensembl chr 4:149,733,625...149,787,028 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma severity IMP RGD PMID:17322108 RGD:38599154 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 exacerbates IMP RGD PMID:33625952 RGD:127229925 NCBI chr14:56,022,452...56,026,314
Ensembl chr14:56,022,452...56,026,322 		JBrowse link
G Tnf tumor necrosis factor IEP protein:increased expression:lung,natural killer cell (mouse) RGD PMID:21887255 RGD:40818252 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16269
    disease by infectious agent 2239
      Bacterial Infections and Mycoses 1087
        bacterial infectious disease 833
          Bacterial Lung Diseases 150
            bacterial pneumonia + 150
            pneumonic tularemia 1
Path 2
Term Annotations click to browse term
  disease 16269
    disease of anatomical entity 15860
      respiratory system disease 5130
        lower respiratory tract disease 2348
          lung disease 2309
            Bacterial Lung Diseases 150
              bacterial pneumonia + 150
              pneumonic tularemia 1
paths to the root