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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Bacterial Lung Diseases
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Accession:DOID:9008559 term browser browse the term
Definition:Pulmonary diseases caused by bacterial infections.
Synonyms:primary_id: RDO:9002453


show annotations for term's descendants           Sort by:
Bacterial Lung Diseases term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Marco macrophage receptor with collagenous structure disease_progression ISO association with Cryptococcal neoformans infection. RGD PMID:28298522 RGD:41412191 NCBI chr13:34,169,011...34,210,340
Ensembl chr13:34,169,011...34,201,255 		JBrowse link
aspiration pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO associated with Cerebrovascular Accident RGD PMID:14990394 RGD:4140926 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP RGD PMID:19515386 RGD:4891456 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IEP RGD PMID:19515386 RGD:4891456 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G Edn1 endothelin 1 IEP protein:increased secretion:plasma (rat) RGD PMID:19262391 RGD:4145069 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Il1a interleukin 1 alpha IEP protein:increased expression:Bronchoalveolar Lavage Fluid RGD PMID:18042282 RGD:4142854 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15607125 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Tnf tumor necrosis factor IEP protein:increased expression:Bronchoalveolar Lavage Fluid RGD PMID:18042282 RGD:4142854 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
bacterial pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 ISO RGD PMID:11238654 RGD:5128828 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404 		JBrowse link
G Ace2 angiotensin converting enzyme 2 ISO associated with Pseudomonas Infections;mRNA, protein:altered expression, altered activity:lung (mouse) RGD PMID:31645418 RGD:40818279 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:33,925,458...33,971,596 		JBrowse link
G Ager advanced glycosylation end product-specific receptor severity ISO RGD PMID:21629785 RGD:6767559 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685 		JBrowse link
G C3 complement C3 ISO RGD PMID:16014897 RGD:5129508 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339 		JBrowse link
G C3ar1 complement C3a receptor 1 ISO RGD PMID:16461429 RGD:5129690 NCBI chr 4:157,747,419...157,756,609
Ensembl chr 4:157,746,089...157,776,323 		JBrowse link
G C5 complement C5 ISO RGD PMID:17975174 RGD:5129707 NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468 		JBrowse link
G Cat catalase IDA protein:decreased expression:lung, plasma RGD PMID:19842849 RGD:5130748 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 ISO mRNA, protein:increased expression:lung RGD PMID:20176793 RGD:5130918 NCBI chr 5:61,759,220...61,761,164
Ensembl chr 5:61,759,220...61,772,022 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO RGD PMID:20042590 RGD:4891443 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 ISO RGD PMID:20483921 RGD:5130905 NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:20042590 RGD:4891443 NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 ISO RGD PMID:20176793 RGD:5130918 NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,593,594...84,604,501 		JBrowse link
G Cd14 CD14 molecule ISO RGD PMID:16210672 RGD:4144197 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Cd40 CD40 molecule ISO RGD PMID:20102413 RGD:5132268 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847 		JBrowse link
G Cd80 Cd80 molecule ISO RGD PMID:20949109 RGD:4892562 NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex ISO RGD PMID:18643924 RGD:5133701 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273 		JBrowse link
G Csf3 colony stimulating factor 3 disease_progression
treatment 		ISO associated with Peritonitis; RGD PMID:21373266 PMID:12352049 RGD:5133733, RGD:11039437 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860 		JBrowse link
G Csf3r colony stimulating factor 3 receptor disease_progression ISO RGD PMID:17185469 RGD:5133739 NCBI chr 5:143,583,126...143,604,382
Ensembl chr 5:143,583,213...143,602,411 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO
IEP 		RGD PMID:21723409 PMID:11052817 RGD:5135062, RGD:5135234 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 severity ISO RGD PMID:16299319 PMID:15618188 RGD:5135458, RGD:5135459 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 ISO RGD PMID:15618188 RGD:5135459 NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,973,720...15,976,567 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 severity ISO
IEP 		RGD PMID:19239431 PMID:11052817 PMID:21723409 RGD:5135065, RGD:5135234, RGD:5135062 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 IEP RGD PMID:11052817 RGD:5135234 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 ISO RGD PMID:19846873 RGD:4145490 NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,594,959...17,596,417 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO RGD PMID:15618188 RGD:5135459 NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO RGD PMID:15618188 RGD:5135459 NCBI chr  X:70,884,293...70,886,944
Ensembl chr  X:70,883,958...70,886,871 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 IEP protein:decreased expression:lung RGD PMID:14766666 RGD:1625385 NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042 		JBrowse link
G Defb4 defensin beta 4 ISO protein:increased expression:plasma RGD PMID:10213993 RGD:4892266 NCBI chr16:77,352,911...77,356,104
Ensembl chr16:77,352,911...77,356,104 		JBrowse link
G Defb5 defensin beta 5 ISO protein:increased expression:plasma RGD PMID:10213993 RGD:4892266 NCBI chr16:77,315,424...77,317,828
Ensembl chr16:77,315,424...77,317,828 		JBrowse link
G F2 coagulation factor II, thrombin IEP protein:increased expression:lung RGD PMID:21897338 RGD:6893486 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G Fcgr2a Fc gamma receptor 2A ISO RGD PMID:17975174 RGD:5129707 NCBI chr13:85,813,516...85,830,269
Ensembl chr13:85,855,437...85,864,394
Ensembl chr13:85,855,437...85,864,394 		JBrowse link
G Foxp3 forkhead box P3 severity ISO RGD PMID:25398094 RGD:38501102 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha exacerbates ISO associated with Escherichia Coli Infections RGD PMID:27845343 RGD:42722624 NCBI chr10:55,831,901...55,856,729
Ensembl chr10:55,829,832...55,854,560 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO mRNA:decreased expression:polymorphonuclear leukocyte RGD PMID:24465168 RGD:126848796 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:211,009,978...211,031,015 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:lung (mouse) RGD PMID:19846873 RGD:4145490 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 severity ISO RGD PMID:19487810 PMID:19487810 RGD:5490274, RGD:5490274 NCBI chr11:44,211,769...44,238,206
Ensembl chr11:44,211,845...44,238,205 		JBrowse link
G Ifng interferon gamma severity ISO RGD PMID:25398094 RGD:38501102 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il10 interleukin 10 severity ISO RGD PMID:25398094 RGD:38501102 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il15 interleukin 15 ISO RGD PMID:17911627 RGD:5000754 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348 		JBrowse link
G Il17a interleukin 17A severity ISO RGD PMID:18802100 PMID:25398094 RGD:4889153, RGD:38501102 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il18 interleukin 18 ISO RGD PMID:17664259 RGD:4889913 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1b interleukin 1 beta severity
treatment 		ISO associated with Agranulocytosis RGD PMID:18596024 PMID:25398094 PMID:7546648 RGD:4143205, RGD:38501102, RGD:10755357 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 treatment ISO
IEP 		associated with Sepsis
associated with Acinetobacter infectious disease 		RGD PMID:20959556 PMID:29508184 RGD:5144223, RGD:40818077 NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO RGD PMID:18596024 PMID:18322242 RGD:4143205, RGD:4143206 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732 		JBrowse link
G Il22 interleukin 22 ISO RGD PMID:21178015 RGD:5147404 NCBI chr 7:55,687,061...55,691,526
Ensembl chr 7:55,686,896...55,692,201 		JBrowse link
G Il6 interleukin 6 severity ISO RGD PMID:25398094 RGD:38501102 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO RGD PMID:28120642 PMID:20439918 RGD:34888234, RGD:36049799 NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:57,539,557...57,598,706 		JBrowse link
G Irf1 interferon regulatory factor 1 ISO RGD PMID:11854220 RGD:5128725 NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947 		JBrowse link
G Irf3 interferon regulatory factor 3 ISO RGD PMID:20720199 RGD:4891951 NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:104,616,469...104,621,401 		JBrowse link
G Itgb3 integrin subunit beta 3 IEP protein:increased expression:lung, neutrophil RGD PMID:15114484 RGD:4993468 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800 		JBrowse link
G Lep leptin ISO RGD PMID:11937559 RGD:5128871 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 severity ISO associated with Escherichia Coli Infections RGD PMID:22514650 RGD:150340681 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mbl2 mannose binding lectin 2 ISO Legionella Pneumonia; DNA:mutations:5' utr, exon:multiple (human) RGD PMID:18641104 RGD:4889477 NCBI chr 1:237,429,873...237,465,567
Ensembl chr 1:237,429,973...237,437,546 		JBrowse link
G Mc1r melanocortin 1 receptor ISO RGD PMID:18304533 RGD:5687324 NCBI chr19:68,360,950...68,363,877
Ensembl chr19:68,360,950...68,363,877 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased expression:bronchoalveolar lavage fluid RGD PMID:17202364 PMID:19535150 RGD:5130727, RGD:5129533 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mpo myeloperoxidase ISO protein:increased activity:bronchoalveolar lavage Fluid: RGD PMID:11269653 RGD:5130992 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 ISO RGD PMID:19360122 RGD:5131449 NCBI chr 4:85,391,142...85,442,281
Ensembl chr 4:85,391,151...85,441,674 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO RGD PMID:19360122 RGD:5131449 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:34,555,832...34,722,846 		JBrowse link
G Pdpn podoplanin IEP protein:increased expression:lung RGD PMID:7864138 RGD:2292375 NCBI chr 5:160,884,995...160,919,112
Ensembl chr 5:160,884,993...160,925,637 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IEP protein:decreased expression:lung RGD PMID:12524254 RGD:724645 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839 		JBrowse link
G Pgf placental growth factor ISO protein:increased expression:plasma RGD PMID:16702604 RGD:6483601 NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:110,547,153...110,557,747 		JBrowse link
G Pten phosphatase and tensin homolog ameliorates ISO myeloid knockout RGD PMID:21527775 RGD:127285594 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 ameliorates ISO RGD PMID:28387756 RGD:127229944 NCBI chr15:33,253,071...33,262,025
Ensembl chr15:33,253,071...33,262,025 		JBrowse link
G Rorc RAR-related orphan receptor C severity ISO RGD PMID:25398094 RGD:38501102 NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:184,698,818...184,724,566 		JBrowse link
G Serpine1 serpin family E member 1 severity ISO RGD PMID:17032919 RGD:4144840 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Sftpa1 surfactant protein A1 IEP protein:increased expression:lung RGD PMID:12169586 RGD:4143464 NCBI chr16:17,042,264...17,045,770
Ensembl chr16:17,042,255...17,045,769 		JBrowse link
G Sftpb surfactant protein B ISO
IEP 		associated with Cystic Fibrosis;protein:increased expression:lung RGD PMID:15271694 PMID:12169586 RGD:4143403, RGD:4143464 NCBI chr 4:105,917,495...105,926,631
Ensembl chr 4:105,917,578...105,927,646 		JBrowse link
G Sftpc surfactant protein C ISO
IEP 		RGD PMID:18566429 PMID:12169586 RGD:4144114, RGD:4143464 NCBI chr15:52,006,274...52,009,324
Ensembl chr15:52,006,283...52,009,475 		JBrowse link
G Sftpd surfactant protein D ISO
IEP 		associated with Cystic Fibrosis;protein:decreased expression:lung
protein:increased expression:lung 		RGD PMID:15271694 PMID:12169586 RGD:4143403, RGD:4143464 NCBI chr16:17,080,575...17,093,047
Ensembl chr16:17,080,567...17,094,036 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO RGD PMID:18192501 RGD:6892945 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 severity ISO RGD PMID:25398094 RGD:38501102 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tlr2 toll-like receptor 2 ISO
IDA 		RGD PMID:18768871 PMID:19844782 RGD:4145337, RGD:4889533 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194 		JBrowse link
G Tlr4 toll-like receptor 4 ISO RGD PMID:20650991 PMID:16210672 RGD:4144172, RGD:4144197 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tlr5 toll-like receptor 5 ISO RGD PMID:19801452 RGD:5129503 NCBI chr13:97,166,430...97,190,642
Ensembl chr13:97,166,405...97,192,525 		JBrowse link
G Tlr6 toll-like receptor 6 IDA RGD PMID:19844782 RGD:4889533 NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,698,751...43,740,462 		JBrowse link
G Tlr9 toll-like receptor 9 ISO RGD PMID:20360853 RGD:5130719 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:115,742,889...115,750,148 		JBrowse link
G Tnf tumor necrosis factor disease_progression
treatment
severity 		ISO associated with Agranulocytosis RGD PMID:10650487 PMID:7546648 PMID:9310939 PMID:12958055 RGD:4143476, RGD:10755357, RGD:10450564, RGD:10449451 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO protein:increased expression:serum (mouse) RGD PMID:19842848 RGD:5131429 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO protein:increased expression:serum (mouse) RGD PMID:19842848 RGD:5131429 NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:162,353,848...162,387,411 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 severity
ameliorates 		ISO
IDA 		RGD PMID:24465168 PMID:16960786 PMID:22996209 RGD:126848796, RGD:127229902, RGD:126925987 NCBI chr 9:20,259,227...20,276,879
Ensembl chr 9:20,261,408...20,276,892 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A ISO associated with Pseudomonas Infections RGD PMID:29695841 RGD:39938967 NCBI chr 5:142,661,193...142,670,051
Ensembl chr 5:142,661,199...142,669,985 		JBrowse link
Chlamydia pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule ISO mRNA:increased expression:lung RGD PMID:26378990 RGD:41412180 NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:236,496,463...236,549,951 		JBrowse link
G Pdcd1 programmed cell death 1 ISO mRNA:increased expression:lung RGD PMID:26378990 RGD:41412180 NCBI chr 9:101,866,124...101,879,278
Ensembl chr 9:101,866,126...101,879,270 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta severity ISO RGD PMID:29893841 RGD:40890270 NCBI chr 5:165,377,994...165,426,620
Ensembl chr 5:165,377,994...165,403,968 		JBrowse link
Klebsiella pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifngr1 interferon gamma receptor 1 disease_progression ISO mRNA:increased expression:monocyte RGD PMID:38898888 RGD:628360927 NCBI chr 1:16,152,811...16,171,439
Ensembl chr 1:16,152,879...16,171,437 		JBrowse link
G Ifngr2 interferon gamma receptor 2 disease_progression ISO mRNA:increased expression:monocyte RGD PMID:38898888 RGD:628360927 NCBI chr11:44,265,703...44,283,975
Ensembl chr11:44,265,703...44,283,975 		JBrowse link
G Il23a interleukin 23 subunit alpha severity ISO RGD PMID:16157683 RGD:39457940 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 severity ISO mRNA:increased expression:lung (mouse) RGD PMID:22729155 PMID:20864681 RGD:35316077, RGD:36049798 NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:57,539,557...57,598,706 		JBrowse link
G Lcn2 lipocalin 2 exacerbates
ameliorates 		ISO protein:increased expression:lung
protein:increased expression:serum 		RGD PMID:29633303 PMID:19342674 PMID:19342674 PMID:19342674 PMID:25234944 More... RGD:126725082, RGD:126725085, RGD:126725085, RGD:126725085, RGD:126725084, RGD:126725084 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842 		JBrowse link
G Plac8 placenta associated 8 severity ISO RGD PMID:17404296 RGD:40924563 NCBI chr14:9,356,950...9,378,586
Ensembl chr14:9,356,972...9,378,572 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 disease_progression ISO RGD PMID:24396044 RGD:126925976 NCBI chr 9:20,259,227...20,276,879
Ensembl chr 9:20,261,408...20,276,892 		JBrowse link
Legionnaires' disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase ISO protein:increased expression:serum RGD PMID:9255891 RGD:5128857 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:16113250 RGD:4891897 NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO mRNA, protein:increased expression:lung RGD PMID:11254553 RGD:5135252 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO mRNA, protein:increased expression:lung RGD PMID:11254553 RGD:5135252 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 ISO mRNA, protein:increased expression:lung RGD PMID:11254553 RGD:5135252 NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,594,959...17,596,417 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO RGD PMID:11254553 RGD:5135252 NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:83,183,808...83,188,602 		JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: therapeutic CTD PMID:11349020 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il18 interleukin 18 ISO RGD PMID:11083766 RGD:4889865 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO RGD PMID:19073229 RGD:12910934 NCBI chr 1:237,429,873...237,465,567
Ensembl chr 1:237,429,973...237,437,546 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 ISO RGD PMID:20685341 RGD:5131443 NCBI chr 4:85,391,142...85,442,281
Ensembl chr 4:85,391,151...85,441,674 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO RGD PMID:20685341 RGD:5131443 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:34,555,832...34,722,846 		JBrowse link
G Tlr5 toll-like receptor 5 susceptibility ISO DNA:nonsense mutation:cds:p.R392X (human)
ClinVar Annotator: match by term: Legionnaire disease, susceptibility to
CTD Direct Evidence: marker/mechanism 		OMIM
ClinVar
CTD
RGD		 PMID:14623910 PMID:16027372 PMID:23447684 PMID:14623910 PMID:17982089 RGD:5129477, RGD:5129510 NCBI chr13:97,166,430...97,190,642
Ensembl chr13:97,166,405...97,192,525 		JBrowse link
G Tlr9 toll-like receptor 9 ISO RGD PMID:18426877 RGD:5130707 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:115,742,889...115,750,148 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO RGD PMID:18838275 RGD:5131445 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO RGD PMID:18838275 RGD:5131445 NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:162,353,848...162,387,411 		JBrowse link
Mycoplasma pneumoniae pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase ISO protein:increased expression:serum RGD PMID:9255891 RGD:5128857 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293 		JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr10:54,817,473...54,823,708
Ensembl chr10:54,817,476...54,823,708 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 ISO RGD PMID:16988274 RGD:4892091 NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO protein:increased secretion:lung, secretion (mouse) RGD PMID:18717637 RGD:4891914 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 ISO protein:increased expression:lung, T-helper cell (mouse) RGD PMID:16988274 RGD:4892091 NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:132,629,683...132,637,594 		JBrowse link
G Clec5a C-type lectin domain containing 5A severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr 4:70,373,855...70,383,560
Ensembl chr 4:70,374,529...70,398,230 		JBrowse link
G Col3a1 collagen type III alpha 1 chain severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,457...11,924,107 		JBrowse link
G Col6a2 collagen type VI alpha 2 chain severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr20:12,021,182...12,048,932
Ensembl chr20:12,021,265...12,057,042 		JBrowse link
G Crp C-reactive protein ISO RGD PMID:21426633 RGD:5131292 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514 		JBrowse link
G Dnase1l3 deoxyribonuclease 1L3 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr15:19,351,683...19,378,536
Ensembl chr15:19,352,493...19,378,531 		JBrowse link
G Fcer2 Fc epsilon receptor II severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr12:6,540,697...6,552,364
Ensembl chr12:6,540,703...6,549,374 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750 		JBrowse link
G Galc galactosylceramidase ISO associated with Guillain-Barre syndrome; protein:increased expression:serum (human)
associated with Guillain-Barre syndrome; protein:increased expression:Cerebrospinal fluid, serum (human)
protein:increased expression:serum (mouse) 		RGD PMID:27490360 PMID:29301655 PMID:30396892 PMID:30396892 PMID:12225900 RGD:38599168, RGD:38599172, RGD:38599171, RGD:38599171, RGD:38599169 NCBI chr 6:123,182,636...123,252,024
Ensembl chr 6:123,182,643...123,245,578 		JBrowse link
G Hdc histidine decarboxylase ISO RGD PMID:17158962 RGD:5143920 NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711 		JBrowse link
G Htra3 HtrA serine peptidase 3 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr14:79,293,535...79,321,936
Ensembl chr14:79,293,541...79,321,936 		JBrowse link
G Ifng interferon gamma ISO mRNA:increased expression:lung: RGD PMID:7935058 RGD:10755754 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il13 interleukin 13 ISO protein:increased expression:serum RGD PMID:20416219 RGD:4145765 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483 		JBrowse link
G Il22ra2 interleukin 22 receptor subunit alpha 2 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr 1:16,172,238...16,228,009
Ensembl chr 1:16,184,113...16,197,950 		JBrowse link
G Inhba inhibin subunit beta A severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508 		JBrowse link
G Klrb1 killer cell lectin like receptor B1 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr 4:164,142,323...164,161,018
Ensembl chr 4:164,142,280...164,161,764 		JBrowse link
G Ms4a1 membrane spanning 4-domains A1 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr 1:217,331,274...217,351,934
Ensembl chr 1:217,331,274...217,343,447 		JBrowse link
G Pld4 phospholipase D family, member 4 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr 6:137,639,948...137,647,462
Ensembl chr 6:137,639,945...137,649,024 		JBrowse link
G Spib Spi-B transcription factor severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr 1:104,155,456...104,161,311
Ensembl chr 1:104,155,464...104,161,517 		JBrowse link
G Tcf7 transcription factor 7 severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr10:36,924,363...36,954,279
Ensembl chr10:36,924,363...36,954,279 		JBrowse link
G Tcl1a Tcl1 family Akt coactivator A severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr 6:129,889,763...129,895,756
Ensembl chr 6:129,887,703...129,896,264 		JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:serum RGD PMID:20416219 RGD:4145765 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf13c TNF receptor superfamily member 13C severity ISO RGD PMID:28302172 RGD:32716376 NCBI chr 7:115,616,139...115,618,647
Ensembl chr 7:115,616,303...115,618,620 		JBrowse link
Pneumococcal Pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase ISO RGD PMID:26456931 RGD:11098923 NCBI chr 4:157,446,120...157,455,958
Ensembl chr 4:157,444,697...157,456,356 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO RGD PMID:20231413 RGD:4890435 NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126 		JBrowse link
G Btk Bruton tyrosine kinase ameliorates ISO RGD PMID:30646846 RGD:124715470 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:102,016,074...102,055,143 		JBrowse link
G C3 complement C3 disease_progression ISO
IEP 		protein:decreased expression:serum
associated with Liver Cirrhosis, Experimental;protein:decreased expression:respiratory system fluid/secretion 		RGD PMID:20405 PMID:15972516 PMID:17956621 RGD:5130163, RGD:5129509, RGD:5129523 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339 		JBrowse link
G C5 complement C5 severity ISO RGD PMID:7814608 RGD:5130159 NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 susceptibility ISO RGD PMID:16455992 RGD:4892130 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Cd14 CD14 molecule ISO RGD PMID:17185649 RGD:4144788 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:increased secretion:serum (human) RGD PMID:10515841 RGD:4892626 NCBI chr13:48,193,839...48,201,822
Ensembl chr13:48,193,800...48,201,825 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO RGD PMID:21774994 RGD:5147472 NCBI chr10:89,540,192...89,583,466
Ensembl chr10:89,540,192...89,583,466 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO RGD PMID:21774994 RGD:5147472 NCBI chr 4:85,553,163...85,596,203
Ensembl chr 4:85,554,268...85,596,318 		JBrowse link
G Crp C-reactive protein disease_progression ISO RGD PMID:21281676 RGD:5131293 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO protein:increased expression:respiratory system fluid/secretion RGD PMID:20958976 RGD:5134957 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO protein:increased expression:lung RGD PMID:20381636 RGD:5135285 NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299 		JBrowse link
G Defb5 defensin beta 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24894820 NCBI chr16:77,315,424...77,317,828
Ensembl chr16:77,315,424...77,317,828 		JBrowse link
G Hmox1 heme oxygenase 1 ISO associated with influenza;protein:increased expression:lung RGD PMID:17348295 RGD:4145366 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hp haptoglobin ISO RGD PMID:19396720 RGD:5147385 NCBI chr19:54,449,151...54,453,701
Ensembl chr19:54,446,217...54,467,518 		JBrowse link
G Il15 interleukin 15 ISO protein:increased expression:alveolar macrophage, bronchial epithelial cell RGD PMID:17611121 RGD:5000755 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348 		JBrowse link
G Il15ra interleukin 15 receptor subunit alpha ISO RGD PMID:17611121 RGD:5000755 NCBI chr17:71,712,141...71,742,072
Ensembl chr17:71,712,141...71,742,149 		JBrowse link
G Il17a interleukin 17A ISO RGD PMID:19995896 RGD:4888531 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il18 interleukin 18 ISO RGD PMID:15770015 RGD:4889960 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il6 interleukin 6 ISO RGD PMID:20643849 RGD:4143255 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Lep leptin ISO RGD PMID:17822444 RGD:5128869 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661 		JBrowse link
G Lepr leptin receptor ISO RGD PMID:21148797 RGD:5128846 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24894820 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24894820 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Masp2 MBL associated serine protease 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12904520 NCBI chr 5:164,319,017...164,332,686
Ensembl chr 5:164,308,991...164,332,705 		JBrowse link
G Mbl2 mannose binding lectin 2 no_association ISO DNA:mutations:5' utr, exon:multiple (human)
DNA:polymorphisms:5' utr, exon:multiple (human) 		RGD PMID:18641104 PMID:12047967 RGD:4889477, RGD:4889478 NCBI chr 1:237,429,873...237,465,567
Ensembl chr 1:237,429,973...237,437,546 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO RGD PMID:17056580 RGD:4891950 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Pten phosphatase and tensin homolog ameliorates ISO myeloid knockout RGD PMID:20505137 RGD:127285597 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330 		JBrowse link
G Sftpd surfactant protein D severity ISO RGD PMID:16255775 RGD:4143519 NCBI chr16:17,080,575...17,093,047
Ensembl chr16:17,080,567...17,094,036 		JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24894820 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 ISO RGD PMID:29263110 RGD:39128230 NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,606,196...27,611,947 		JBrowse link
G Tlr2 toll-like receptor 2 ISO RGD PMID:19956717 RGD:4145321 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194 		JBrowse link
G Tnf tumor necrosis factor ISO associated with influenza;protein:increased expression:lung RGD PMID:9032201 PMID:17348295 RGD:4143479, RGD:4145366 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ameliorates ISO RGD PMID:24752755 PMID:19596984 RGD:126928121, RGD:127229903 NCBI chr 9:20,259,227...20,276,879
Ensembl chr 9:20,261,408...20,276,892 		JBrowse link
pneumonic tularemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ido1 indoleamine 2,3-dioxygenase 1 ISO RGD PMID:20385761 RGD:39938865 NCBI chr16:74,133,259...74,145,328
Ensembl chr16:74,133,259...74,145,328 		JBrowse link
Staphylococcal Pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 treatment ISO RGD PMID:23613163 RGD:38676477 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Cd86 CD86 molecule ISO protein:decreased expression:spleen, plasmacytoid dendritic cell (mouse) RGD PMID:20949109 RGD:4892562 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361 		JBrowse link
G Cftr CF transmembrane conductance regulator ISO RGD PMID:28289144 RGD:36049750 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:10228098 RGD:11039478 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860 		JBrowse link
G Fn1 fibronectin 1 IDA RGD PMID:12065530 RGD:7205474 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 susceptibility ISO RGD PMID:19603548 PMID:19603548 RGD:5490273, RGD:5490273 NCBI chr11:44,211,769...44,238,206
Ensembl chr11:44,211,845...44,238,205 		JBrowse link
G Il10 interleukin 10 ISO mRNA, protein:increased expression:lung RGD PMID:22940620 RGD:7364825 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il15 interleukin 15 ISO RGD PMID:18390740 RGD:4996474 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348 		JBrowse link
G Il1b interleukin 1 beta ISO RGD PMID:20065029 RGD:4142828 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il33 interleukin 33 ISO mRNA:increased expression:lung: RGD PMID:28401938 RGD:40400699 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO RGD PMID:20493961 RGD:5131444 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:34,555,832...34,722,846 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO protein:increased expression:lung (mouse) RGD PMID:28663335 RGD:13432209 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 severity ISO mRNA:increased expression:lung
associated with influenza 		RGD PMID:31782850 PMID:31782850 RGD:39131288, RGD:39131288 NCBI chr12:41,026,079...41,085,577
Ensembl chr12:41,043,785...41,085,577 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 treatment ISO RGD PMID:25445964 RGD:127229910 NCBI chr15:33,253,071...33,262,025
Ensembl chr15:33,253,071...33,262,025 		JBrowse link
G Sftpb surfactant protein B ameliorates ISO RGD PMID:20007532 RGD:151667448 NCBI chr 4:105,917,495...105,926,631
Ensembl chr 4:105,917,578...105,927,646 		JBrowse link
Streptococcus pneumonia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase exacerbates ISO RGD PMID:27421701 RGD:126779562 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G Btk Bruton tyrosine kinase ISO RGD PMID:30873567 RGD:124715473 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:102,016,074...102,055,143 		JBrowse link
G Clec4m C-type lectin domain family 4 member M severity ISO RGD PMID:16134084 RGD:39938986 NCBI chr12:6,713,795...6,722,414
Ensembl chr12:6,713,812...6,722,410 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 ISO mRNA:increased expression:lung (mouse) RGD PMID:20385761 RGD:39938865 NCBI chr16:74,133,259...74,145,328
Ensembl chr16:74,133,259...74,145,328 		JBrowse link
G Ifng interferon gamma ISO protein:increased expression:lung,natural killer cell (mouse) RGD PMID:21887255 RGD:40818252 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il6 interleukin 6 ISO protein:increased expression:lung,natural killer cell (mouse) RGD PMID:21887255 RGD:40818252 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 severity ISO RGD PMID:22492852 RGD:35316076 NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:57,539,557...57,598,706 		JBrowse link
G Itgb2 integrin subunit beta 2 susceptibility ISO RGD PMID:11390487 RGD:127345090 NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,058,492...11,097,182 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 ISO protein:increased expression:lung, natural killer cell (mouse) RGD PMID:21887255 RGD:40818252 NCBI chr16:83,058,131...83,082,843
Ensembl chr16:83,058,385...83,075,159 		JBrowse link
G Marco macrophage receptor with collagenous structure exacerbates ISO RGD PMID:15263032 RGD:41412189 NCBI chr13:34,169,011...34,210,340
Ensembl chr13:34,169,011...34,201,255 		JBrowse link
G Ncr1 natural cytotoxicity triggering receptor 1 severity ISO RGD PMID:21887255 RGD:40818252 NCBI chr 1:78,657,409...78,665,255
Ensembl chr 1:78,659,262...78,703,273 		JBrowse link
G Pdcd1 programmed cell death 1 treatment ISO RGD PMID:25624454 RGD:40818422 NCBI chr 9:101,866,124...101,879,278
Ensembl chr 9:101,866,126...101,879,270 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta treatment ISO associated with immunodeficiency 14 RGD PMID:30093657 RGD:40890269 NCBI chr 5:165,377,994...165,426,620
Ensembl chr 5:165,377,994...165,403,968 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma severity ISO RGD PMID:17322108 RGD:38599154 NCBI chr 6:54,494,247...54,529,563
Ensembl chr 6:54,478,603...54,529,509 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 exacerbates ISO RGD PMID:33625952 RGD:127229925 NCBI chr15:33,253,071...33,262,025
Ensembl chr15:33,253,071...33,262,025 		JBrowse link
G Tnf tumor necrosis factor ISO protein:increased expression:lung,natural killer cell (mouse) RGD PMID:21887255 RGD:40818252 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14566
    disease by infectious agent 1953
      Bacterial Infections and Mycoses 798
        bacterial infectious disease 663
          Bacterial Lung Diseases 150
            bacterial pneumonia + 150
            pneumonic tularemia 1
Path 2
Term Annotations click to browse term
  disease 14566
    disease of anatomical entity 13676
      respiratory system disease 3830
        lower respiratory tract disease 1972
          lung disease 1934
            Bacterial Lung Diseases 150
              bacterial pneumonia + 150
              pneumonic tularemia 1
paths to the root