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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Tendon Injuries
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Accession:DOID:9008331 term browser browse the term
Definition:Injuries to the fibrous cords of connective tissue which attach muscles to bones or other structures.
Synonyms:exact_synonym: Tendon Injury
 narrow_synonym: Achilles tendon injury
 primary_id: MESH:D013708
 xref: EFO:0600078


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Tendon Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan IEP mRNA:increased expression:patellar ligament (rat) RGD PMID:19955224 RGD:2315073 NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:132,981,582...133,043,627 		JBrowse link
G Col1a1 collagen type I alpha 1 chain treatment IDA RGD PMID:20479531 RGD:8552700 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Egr1 early growth response 1 treatment IDA RGD PMID:23519232 RGD:10395300 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 treatment IDA RGD PMID:23519232 RGD:10395300 NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit treatment IDA RGD PMID:23519232 RGD:10395300 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit treatment IDA RGD PMID:23519232 RGD:10395300 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Gdf5 growth differentiation factor 5 treatment ISO RGD PMID:17507245 PMID:16419971 RGD:12738226, RGD:12738229 NCBI chr 3:164,914,401...164,918,593
Ensembl chr 3:144,454,338...144,458,612 		JBrowse link
G Mmp3 matrix metallopeptidase 3 IEP associated with Diabetes Mellitus, Type 2;mRNA:decreased expression:tendon RGD PMID:23042903 RGD:8694102 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Postn periostin IEP protein:increased expression:achilles tendon: RGD PMID:23149902 RGD:10041033 NCBI chr 2:140,677,774...140,709,304
Ensembl chr 2:138,527,696...138,559,099 		JBrowse link
G Rgs1 regulator of G-protein signaling 1 treatment IDA RGD PMID:23519232 RGD:10395300 NCBI chr13:58,568,844...58,573,187
Ensembl chr13:56,018,554...56,022,984 		JBrowse link
Rotator Cuff Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ngf nerve growth factor IEP mRNA,protein:increased expression:rotator cuff RGD PMID:30146165 RGD:402463951 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 IEP protein:increased expression:tendon: RGD PMID:29891998 RGD:127284862 NCBI chr 9:20,259,227...20,276,879
Ensembl chr 9:12,763,819...12,779,203 		JBrowse link
tendinitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn2 cellular communication network factor 2 IEP protein:increased expression:flexor digitorum profundus, flexor digitorum superficialis, fibroblast (rat) RGD PMID:19743505 RGD:2314473 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Fmod fibromodulin IEP RGD PMID:19955224 RGD:2315073 NCBI chr13:48,045,567...48,056,184
Ensembl chr13:45,493,517...45,504,133 		JBrowse link
G Lrp5 LDL receptor related protein 5 IEP protein:increased expression:patellar tendon: RGD PMID:23776285 RGD:12793064 NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:200,814,250...200,917,581 		JBrowse link
G Mmp1 matrix metallopeptidase 1 IEP RGD PMID:22926534 RGD:8549751 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Postn periostin IEP protein:increased expression:peritendon: RGD PMID:19743505 RGD:2314473 NCBI chr 2:140,677,774...140,709,304
Ensembl chr 2:138,527,696...138,559,099 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19139
    Wounds and Injuries 1000
      Tendon Injuries 16
        Rotator Cuff Injuries 2
        tendinitis + 5
paths to the root