RGD DISEASE ONTOLOGY - ANNOTATIONS |
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RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
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Term: | Neoplastic Processes |
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Accession: | DOID:9008192
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browse the term
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Definition: | The pathological mechanisms and forms taken by tissue during degeneration into a neoplasm and its subsequent activity. |
Synonyms: | primary_id: | MESH:D009385 |
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APOBEC3B |
apolipoprotein B mRNA editing enzyme catalytic subunit 3B |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26258849 |
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NCBI chr 5:9,098,676...9,115,965
Ensembl chr 5:9,097,719...9,116,369
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CHAF1B |
chromatin assembly factor 1 subunit B |
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ISO |
protein:increased expression:: |
RGD |
PMID:22882088 |
RGD:9587477 |
NCBI chr13:200,048,096...200,074,902
Ensembl chr13:200,048,149...200,072,556
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ERG |
ETS transcription factor ERG |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27783944 |
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NCBI chr13:201,999,237...202,302,572
Ensembl chr13:202,000,995...202,301,368
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ETV1 |
ETS variant transcription factor 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27783944 |
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NCBI chr 9:83,322,818...83,567,136
Ensembl chr 9:83,322,823...83,418,902
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ETV4 |
ETS variant transcription factor 4 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27783944 |
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NCBI chr12:19,531,507...19,548,303
Ensembl chr12:19,531,603...19,548,301
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ETV5 |
ETS variant transcription factor 5 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27783944 |
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NCBI chr13:123,873,346...123,930,292
Ensembl chr13:123,873,350...123,930,200
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EWSR1 |
EWS RNA binding protein 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27783944 |
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NCBI chr14:46,408,636...46,439,357
Ensembl chr14:46,408,649...46,439,453
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HDLBP |
high density lipoprotein binding protein |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25129143 |
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NCBI chr15:139,957,703...140,025,336
Ensembl chr15:139,957,715...140,022,302
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HOXD9 |
homeobox D9 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26075790 |
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NCBI chr15:81,910,415...81,926,276
Ensembl chr15:81,924,142...81,926,274
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HRAS |
HRas proto-oncogene, GTPase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:12082015 |
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NCBI chr 2:299,662...302,539
Ensembl chr 2:299,660...302,501
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CA9 |
carbonic anhydrase 9 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19808899 |
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NCBI chr 1:236,393,727...236,400,994
Ensembl chr 1:236,394,306...236,400,822
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HIF1A |
hypoxia inducible factor 1 subunit alpha |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19808899 |
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NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845
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AICDA |
activation induced cytidine deaminase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21570118 |
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NCBI chr 5:62,777,236...62,787,342
Ensembl chr 5:62,777,352...62,787,369
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BCR |
BCR activator of RhoGEF and GTPase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21570118 |
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NCBI chr14:49,208,662...49,322,109
Ensembl chr14:49,208,762...49,322,103
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ESR2 |
estrogen receptor 2 |
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ISO |
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RGD |
PMID:12740446 |
RGD:734951 |
NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,829,560...193,906,565
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HMOX1 |
heme oxygenase 1 |
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ISO |
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RGD |
PMID:22139798 |
RGD:10755566 |
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MIR150-1 |
microRNA mir-150-1 |
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ISO |
miRNA:decreased expression:leukocytes |
RGD |
PMID:21501493 |
RGD:13782140 |
NCBI chr 6:54,580,912...54,580,988
Ensembl chr 6:54,580,912...54,580,988
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TCN2 |
transcobalamin 2 |
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ISO |
protein:increased expression:: |
RGD |
PMID:1059479 |
RGD:11060122 |
NCBI chr14:47,496,245...47,515,966
Ensembl chr14:47,502,715...47,515,965
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ALOX12 |
arachidonate 12-lipoxygenase, 12S type |
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ISO |
associated with Prostatic Neoplasms; |
RGD |
PMID:14669797 |
RGD:1578303 |
NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,401,810...52,414,903
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BRIP1 |
BRCA1 interacting helicase 1 |
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ISO |
associated with Breast Neoplasms; human gene in a mouse model |
RGD |
PMID:22875853 |
RGD:11252149 |
NCBI chr12:36,498,138...36,639,847
Ensembl chr12:36,498,205...36,635,973
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CXCR4 |
C-X-C motif chemokine receptor 4 |
disease_progression |
ISO |
associated with hepatocellular carcinoma;protein:increased expression:liver (human) |
RGD |
PMID:19508713 |
RGD:152023653 |
NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,232
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ENPP1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 |
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ISO |
associated with Breast Neoplasms;mRNA:increased expression:bone element (human) |
RGD |
PMID:23861746 |
RGD:13204736 |
NCBI chr 1:31,724,290...31,796,594
Ensembl chr 1:31,722,721...31,796,595
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MMP13 |
matrix metallopeptidase 13 |
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ISO |
associated with Carcinoma, Renal Cell; mRNA, protein:increased expression:bone (human) |
RGD |
PMID:18709334 |
RGD:2306080 |
NCBI chr 9:33,549,003...33,616,700
Ensembl chr 9:33,549,008...33,561,162
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PDGFD |
platelet derived growth factor D |
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ISO |
associated with prostate carcinoma |
RGD |
PMID:22158043 |
RGD:13506772 |
NCBI chr 9:34,388,636...34,621,227
Ensembl chr 9:34,388,643...34,621,244
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ABL1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23968727 |
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NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,708
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ADPRH |
ADP-ribosylarginine hydrolase |
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ISO |
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RGD |
PMID:21697277 |
RGD:13838723 |
NCBI chr13:140,638,526...140,681,631
Ensembl chr13:140,673,101...140,681,260
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AKR1A1 |
aldo-keto reductase family 1 member A1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:32805337 |
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NCBI chr 6:165,811,245...165,825,168
Ensembl chr 6:165,811,247...165,824,896
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AKT1 |
AKT serine/threonine kinase 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:32045588 |
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BRAF |
B-Raf proto-oncogene, serine/threonine kinase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24717435 |
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NCBI chr18:8,957,963...9,132,558
Ensembl chr18:8,957,991...9,132,553
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CAV1 |
caveolin 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29247004 |
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NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465
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CDKN2A |
cyclin dependent kinase inhibitor 2A |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21526190 |
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NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854
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CUX1 |
cut like homeobox 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24316979 |
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NCBI chr 3:9,317,145...9,669,999
Ensembl chr 3:9,317,140...9,669,998
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DNMT1 |
DNA methyltransferase 1 |
disease_progression |
ISO |
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RGD |
PMID:21163286 |
RGD:9588222 |
NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844
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DNMT3A |
DNA methyltransferase 3 alpha |
disease_progression |
ISO |
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RGD |
PMID:21163286 |
RGD:9588222 |
NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,603,087
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EPAS1 |
endothelial PAS domain protein 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26735578 |
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NCBI chr 3:94,167,759...94,253,662
Ensembl chr 3:94,165,816...94,254,079
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ERBB2 |
erb-b2 receptor tyrosine kinase 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25221644 |
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NCBI chr12:22,591,621...22,621,384
Ensembl chr12:22,590,725...22,621,351
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GATA3 |
GATA binding protein 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:35115686 |
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NCBI chr10:63,367,684...63,397,977
Ensembl chr10:63,367,663...63,388,859
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ISG15 |
ISG15 ubiquitin like modifier |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:35506701 |
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NCBI chr 6:63,363,201...63,364,211
Ensembl chr 6:63,363,173...63,364,208
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KRAS |
KRAS proto-oncogene, GTPase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26595770 PMID:29247004 |
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NCBI chr 5:48,508,774...48,546,260
Ensembl chr 5:48,508,811...48,549,358
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MAP3K8 |
mitogen-activated protein kinase kinase kinase 8 |
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ISO |
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RGD |
PMID:15287022 PMID:23533274 |
RGD:151356924 RGD:151356978 |
NCBI chr10:40,714,004...40,746,390
Ensembl chr10:40,713,847...40,742,462
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MET |
MET proto-oncogene, receptor tyrosine kinase |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:32045588 |
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NCBI chr18:29,426,044...29,541,526
Ensembl chr18:29,426,048...29,541,512
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MIR143 |
microRNA mir-143 |
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ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:28736328 |
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NCBI chr 2:150,578,738...150,578,817
Ensembl chr 2:150,578,738...150,578,817
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NFE2L2 |
NFE2 like bZIP transcription factor 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29228771 |
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NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183
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PAFAH1B1 |
platelet activating factor acetylhydrolase 1b regulatory subunit 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24487275 |
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NCBI chr12:48,567,329...48,735,836
Ensembl chr12:48,628,816...48,735,834
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POU5F1 |
POU class 5 homeobox 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:35506701 |
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NCBI chr 7:23,564,654...23,570,691
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SPARC |
secreted protein acidic and cysteine rich |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26783756 |
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NCBI chr16:71,368,164...71,380,972
Ensembl chr16:71,357,586...71,381,161
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TNFSF8 |
TNF superfamily member 8 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:11552987 |
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NCBI chr 1:255,436,206...255,459,020
Ensembl chr 1:255,432,969...255,459,073
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ERBB2 |
erb-b2 receptor tyrosine kinase 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29044505 |
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NCBI chr12:22,591,621...22,621,384
Ensembl chr12:22,590,725...22,621,351
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ACE |
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
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ISO |
associated with colorectal cancer;mRNA:increased expression:liver (mouse) |
RGD |
PMID:20380732 |
RGD:25671446 |
NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,703
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BRAF |
B-Raf proto-oncogene, serine/threonine kinase |
severity |
ISO |
associated with colorectal cancer;DNA:mutations:multiple associated with colorectal cancer;DNA:mutation:cds: associated with colorectal cancer;DNA:missense mutation:cds:p.V600E (human) associated with skin melanoma;DNA:missense mutations:cds: associated with colorectal cancer;DNA:missense mutations:cds:pV599E,p.V600E (human) |
RGD |
PMID:22331825 PMID:23010994 PMID:26775732 PMID:27737491 PMID:28787433 |
RGD:11554843 RGD:14696791 RGD:15039394 RGD:18337264 RGD:18337265 |
NCBI chr18:8,957,963...9,132,558
Ensembl chr18:8,957,991...9,132,553
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CCL2 |
chemokine (C-C motif) ligand 2 |
disease_progression |
ISO |
associated with colorectal cancer |
RGD |
PMID:27058904 |
RGD:14995463 |
NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026
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CCL5 |
C-C motif chemokine ligand 5 |
treatment |
ISO |
associated with Animal Mammary Neoplasms; |
RGD |
PMID:15692764 |
RGD:14995455 |
NCBI chr12:39,652,731...39,659,121
Ensembl chr12:39,648,598...39,659,118
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CCND2 |
cyclin D2 |
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ISO |
associated with colorectal cancer;protein:increased expression:colorectum |
RGD |
PMID:19508551 |
RGD:151665111 |
NCBI chr 5:66,092,483...66,114,575
Ensembl chr 5:66,087,379...66,114,571
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CCNG1 |
cyclin G1 |
treatment |
ISO |
human cells in mouse model |
RGD |
PMID:10910035 |
RGD:151356987 |
NCBI chr16:60,349,255...60,356,737
Ensembl chr16:60,349,258...60,356,738
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CD44 |
CD44 molecule |
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ISO |
associated with Breast Neoplasm;protein:increased expression:liver |
RGD |
PMID:17991717 |
RGD:2289349 |
NCBI chr 2:25,788,699...25,884,209
Ensembl chr 2:25,788,703...25,884,153
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CHD4 |
chromodomain helicase DNA binding protein 4 |
ameliorates |
ISO |
associated with human colon adenocarcinoma cells in a mouse model |
RGD |
PMID:28486105 |
RGD:153323299 |
NCBI chr 5:64,071,627...64,105,212
Ensembl chr 5:64,065,992...64,105,173
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CXCL10 |
C-X-C motif chemokine ligand 10 |
treatment |
ISO |
associated with colon carcinoma; |
RGD |
PMID:30381616 |
RGD:27095891 |
NCBI chr 8:71,693,641...71,695,948
Ensembl chr 8:71,693,339...71,695,948
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CXCL12 |
C-X-C motif chemokine ligand 12 |
ameliorates |
ISO |
associated with colorectal cancer; human cells in mouse model |
RGD |
PMID:30789971 |
RGD:151893289 |
NCBI chr14:91,516,383...91,543,857
Ensembl chr14:91,516,431...91,552,752
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CXCL8 |
C-X-C motif chemokine ligand 8 |
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ISO |
associated with colorectal cancer; human colon adenocarcinoma cells in a mouse model |
RGD |
PMID:29679563 |
RGD:26884358 |
NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
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CXCR4 |
C-X-C motif chemokine receptor 4 |
ameliorates |
ISO |
associated with colorectal cancer; human cells in mouse model human cells in mouse model; associated with colorectal cancer |
RGD |
PMID:29436696 PMID:30789971 |
RGD:151893289 RGD:152023643 |
NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,232
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DAXX |
death domain associated protein |
exacerbates |
ISO |
associated with colon cancer; mRNA:decreased expression:liver (human) associated with pancreatic endocrine carcinoma;DNA:mutations:CDS:multiple (human) associated with neuroendocrine tumor;DNA:mutations:CDS:multiple (human) |
RGD |
PMID:30339629 PMID:30342802 PMID:31942198 |
RGD:152025194 RGD:152025199 RGD:152025203 |
NCBI chr 7:29,676,854...29,681,145
Ensembl chr 7:29,676,856...29,681,110
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DDR1 |
discoidin domain receptor tyrosine kinase 1 |
treatment |
ISO |
mRNA:increased expression:liver (mouse) human cells in mouse model; nilotinib |
RGD |
PMID:29438985 PMID:30666650 PMID:33110221 |
RGD:151347537 RGD:151347685 RGD:151347840 |
NCBI chr 7:23,371,358...23,391,585
Ensembl chr 7:23,373,845...23,391,584
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DDR2 |
discoidin domain receptor tyrosine kinase 2 |
ameliorates |
ISO |
associated with colon carcinoma associated with melanoma; |
RGD |
PMID:21701781 PMID:22071959 |
RGD:150429701 RGD:150429713 |
NCBI chr 4:87,749,738...87,911,818
Ensembl chr 4:87,756,168...87,911,296
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DOCK6 |
dedicator of cytokinesis 6 |
ameliorates |
ISO |
associated with stomach cancer; |
RGD |
PMID:29587866 |
RGD:155791564 |
NCBI chr 2:69,925,853...69,972,326
Ensembl chr 2:69,925,854...69,972,316
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FBXW7 |
F-box and WD repeat domain containing 7 |
disease_progression |
ISO |
associated with colorectal cancer; |
RGD |
PMID:28846828 |
RGD:21408566 |
NCBI chr 8:76,482,027...76,699,354
Ensembl chr 8:76,482,844...76,699,348
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FGFR1 |
fibroblast growth factor receptor 1 |
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ISO |
associated with colorectal cancer;mRNA:increased expression:colorectal mucosa: |
RGD |
PMID:19082464 |
RGD:25330357 |
NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,724
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FOSL2 |
FOS like 2, AP-1 transcription factor subunit |
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ISO |
human cells in mouse model |
RGD |
PMID:30114390 |
RGD:153344554 |
NCBI chr 3:110,820,403...110,842,903
Ensembl chr 3:110,823,666...110,843,068
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GPC3 |
glypican 3 |
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ISO |
protein:increased expression:blood serum (human) |
RGD |
PMID:28801286 |
RGD:243065135 |
NCBI chr X:109,536,495...109,973,605
Ensembl chr X:109,536,504...109,973,607
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HMBS |
hydroxymethylbilane synthase |
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ISO |
associated with colon adenocarcinoma;protein:decreased activity:liver(rat) |
RGD |
PMID:1386052 |
RGD:25440496 |
NCBI chr 9:46,300,039...46,308,681
Ensembl chr 9:46,300,050...46,308,868
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IL2 |
interleukin 2 |
treatment |
ISO |
associated with Colorectal Neoplasms, Carcinoma, Hepatocellular; associated with colon carcinoma |
RGD |
PMID:9354462 PMID:11591892 |
RGD:14928215 RGD:8663446 |
NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609
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IQSEC1 |
IQ motif and Sec7 domain ArfGEF 1 |
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ISO |
human cells in mouse model |
RGD |
PMID:22662237 |
RGD:153344589 |
NCBI chr13:71,203,967...71,366,685
Ensembl chr13:71,031,001...71,366,684
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MAP2K7 |
mitogen-activated protein kinase kinase 7 |
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ISO |
associated with colon cancer;protein:increased expression:colon (human) |
RGD |
PMID:24533778 |
RGD:155259116 |
NCBI chr 2:71,299,010...71,308,432
Ensembl chr 2:71,298,325...71,308,124
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MIR148B |
microRNA mir-148b |
exacerbates |
ISO |
associated with stomach cancer; |
RGD |
PMID:29587866 |
RGD:155791564 |
NCBI chr 5:19,530,990...19,531,069
Ensembl chr 5:19,530,985...19,531,074
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MIR155 |
microRNA mir-155 |
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ISO |
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RGD |
PMID:26885061 |
RGD:21079444 |
NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902
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G |
MPL |
MPL proto-oncogene, thrombopoietin receptor |
exacerbates severity |
ISO |
associated with pancreatic cancer; protein:increased expression:liver, pancreas (human) associated with colorectal carcinoma;protein:increased expression:colorectum (human) associated with pancreatic ductal adenocarcinoma; human cells in mouse model |
RGD |
PMID:23747337 PMID:30770989 |
RGD:126925751 RGD:126925752 |
NCBI chr 6:167,896,191...167,908,988
Ensembl chr 6:167,896,287...167,908,625
|
|
G |
NRAS |
NRAS proto-oncogene, GTPase |
susceptibility |
ISO |
associated with colorectal cancer;DNA:mutations:exons (human) associated with melanoma;DNA:mutations: exons (human) human gene in a mouse model;DNA:missense mutations:cds:p.G12V, p.Q61K (human) |
RGD |
PMID:26799184 PMID:28011498 PMID:28787433 |
RGD:14696774 RGD:14696791 RGD:14696792 |
NCBI chr 4:105,845,913...105,853,769
Ensembl chr 4:105,845,872...105,858,227
|
|
G |
PTPRB |
protein tyrosine phosphatase receptor type B |
treatment |
ISO |
mouse tumor cells in mouse recipient |
RGD |
PMID:31348125 |
RGD:151660353 |
NCBI chr 5:34,656,460...34,794,838
Ensembl chr 5:34,659,964...34,794,289
|
|
G |
RICTOR |
RPTOR independent companion of MTOR complex 2 |
disease_progression |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:30404068 |
RGD:152995463 |
NCBI chr16:24,109,934...24,250,019
Ensembl chr16:24,109,939...24,311,132
|
|
G |
RNF43 |
ring finger protein 43 |
|
ISO |
associated with colorectal adenocarcinoma;mRNA:increased expression:liver (human) |
RGD |
PMID:28789449 |
RGD:151361221 |
NCBI chr12:34,631,574...34,695,021
Ensembl chr12:34,635,228...34,694,378
|
|
G |
SLC3A2 |
solute carrier family 3 member 2 |
severity |
ISO |
associated with colon adenocarcinoma |
RGD |
PMID:11745822 |
RGD:151361130 |
NCBI chr 2:8,892,071...8,919,070
Ensembl chr 2:8,892,089...8,919,072
|
|
G |
SLC7A5 |
solute carrier family 7 member 5 |
severity |
ISO |
associated with colon adenocarcinoma associated with colon cancer |
RGD |
PMID:11718450 PMID:11745822 |
RGD:151361129 RGD:151361130 |
NCBI chr 6:1,545,940...1,574,298
Ensembl chr 6:1,545,944...1,574,285
|
|
G |
SMAD4 |
SMAD family member 4 |
treatment |
ISO |
associated with colorectal carcinoma;protein:decreased expression:colorectum: associated with colorectal carcinoma; DNA:mutations: : |
RGD |
PMID:17390050 PMID:29551247 |
RGD:18937000 RGD:21066338 |
NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,589,850...100,628,029
|
|
G |
SOX30 |
SRY-box transcription factor 30 |
ameliorates |
ISO |
|
RGD |
PMID:29739711 |
RGD:151660333 |
NCBI chr16:65,642,107...65,677,693
Ensembl chr16:65,642,223...65,678,047
|
|
G |
SRC |
SRC proto-oncogene, non-receptor tyrosine kinase |
disease_progression |
ISO |
associated with colon cancer;protein:increased activity:colon |
RGD |
PMID:7678609 |
RGD:150521542 |
NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860
|
|
G |
VEGFA |
vascular endothelial growth factor A |
|
ISO |
associated with colorectal carcinoma;mRNA,protein:increased expression:liver: |
RGD |
PMID:22156924 |
RGD:15014782 |
NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366
|
|
|
G |
ADAM28 |
ADAM metallopeptidase domain 28 |
ameliorates |
ISO |
associated with lung adenocarcinoma; associated with lung carcinoma, breast carcinoma |
RGD |
PMID:22636800 PMID:26800504 |
RGD:11531771 RGD:153297785 |
NCBI chr14:8,375,169...8,438,622
Ensembl chr14:8,375,212...8,438,615
|
|
G |
ARHGAP5 |
Rho GTPase activating protein 5 |
|
ISO |
associated with Mammary Neoplasms, Experimental |
RGD |
PMID:20860838 |
RGD:126848767 |
NCBI chr 7:67,494,237...67,631,461
Ensembl chr 7:67,494,941...67,594,197
|
|
G |
ARID2 |
AT-rich interaction domain 2 |
exacerbates |
ISO |
associated with hepatocellular carcinoma, |
RGD |
PMID:32071245 |
RGD:150340708 |
NCBI chr 5:76,637,385...76,800,155
Ensembl chr 5:76,636,967...76,797,043
|
|
G |
AZGP1 |
alpha-2-glycoprotein 1, zinc-binding |
ameliorates |
ISO |
associated with hepatocellular carcinoma; |
RGD |
PMID:26902423 PMID:27993894 |
RGD:153350132 RGD:153350133 |
NCBI chr 3:7,867,521...7,874,857
|
|
G |
CA12 |
carbonic anhydrase 12 |
ameliorates |
ISO |
associated with breast cancer; |
RGD |
PMID:29786141 |
RGD:155226861 |
NCBI chr 1:108,649,277...108,710,658
Ensembl chr 1:108,649,271...108,710,651
|
|
G |
CBLB |
Cbl proto-oncogene B |
severity |
ISO |
associated with stomach carcinoma; |
RGD |
PMID:28334634 |
RGD:150540337 |
NCBI chr13:153,480,525...153,700,115
Ensembl chr13:153,395,978...153,700,056
|
|
G |
CCNG1 |
cyclin G1 |
|
ISO |
|
RGD |
PMID:30565428 |
RGD:151361205 |
NCBI chr16:60,349,255...60,356,737
Ensembl chr16:60,349,258...60,356,738
|
|
G |
CHD4 |
chromodomain helicase DNA binding protein 4 |
ameliorates |
ISO |
associated with human colon adenocarcinoma cells in a mouse model |
RGD |
PMID:28486105 |
RGD:153323299 |
NCBI chr 5:64,071,627...64,105,212
Ensembl chr 5:64,065,992...64,105,173
|
|
G |
COL10A1 |
collagen type X alpha 1 chain |
ameliorates |
ISO |
associated with H1299 cell |
RGD |
PMID:33324550 |
RGD:150429752 |
NCBI chr 1:81,766,829...81,773,818
Ensembl chr 1:81,765,859...81,773,818
|
|
G |
CXCR4 |
C-X-C motif chemokine receptor 4 |
ameliorates |
ISO |
associated with colorectal cancer; human cells in mouse model associated with nasopharynx carcinoma; human cells in mouse model associated with osteosarcoma and melanoma |
RGD |
PMID:16000558 PMID:18071913 PMID:26498029 PMID:31938138 |
RGD:151665329 RGD:151893515 RGD:152023752 RGD:152177473 |
NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,232
|
|
G |
DDR1 |
discoidin domain receptor tyrosine kinase 1 |
|
ISO |
|
RGD |
PMID:29483153 |
RGD:151347599 |
NCBI chr 7:23,371,358...23,391,585
Ensembl chr 7:23,373,845...23,391,584
|
|
G |
DDR2 |
discoidin domain receptor tyrosine kinase 2 |
exacerbates |
ISO |
associated with tongue squamous cell carcinoma; |
RGD |
PMID:24556606 |
RGD:150429746 |
NCBI chr 4:87,749,738...87,911,818
Ensembl chr 4:87,756,168...87,911,296
|
|
G |
FASN |
fatty acid synthase |
|
ISO |
associated with head and neck squamous cell carcinoma |
RGD |
PMID:20604875 |
RGD:126790467 |
NCBI chr12:922,405...937,560
Ensembl chr12:920,509...937,561
|
|
G |
FOSL2 |
FOS like 2, AP-1 transcription factor subunit |
|
ISO |
human cells in mouse model |
RGD |
PMID:30326930 |
RGD:153344557 |
NCBI chr 3:110,820,403...110,842,903
Ensembl chr 3:110,823,666...110,843,068
|
|
G |
HILPDA |
hypoxia inducible lipid droplet associated |
|
ISO |
human cells in mouse model |
RGD |
PMID:31142329 |
RGD:153344574 |
NCBI chr18:19,944,929...19,947,080
Ensembl chr18:19,944,930...19,947,080
|
|
G |
IQSEC1 |
IQ motif and Sec7 domain ArfGEF 1 |
|
ISO |
human cells in mouse model |
RGD |
PMID:18084281 |
RGD:153344604 |
NCBI chr13:71,203,967...71,366,685
Ensembl chr13:71,031,001...71,366,684
|
|
G |
ITGAV |
integrin subunit alpha V |
treatment |
ISO |
human cells in rat model |
RGD |
PMID:20841470 |
RGD:152998949 |
NCBI chr15:91,604,666...91,711,843
Ensembl chr15:91,604,676...91,711,851
|
|
G |
MAP3K1 |
mitogen-activated protein kinase kinase kinase 1 |
ameliorates |
ISO |
associated with breast carcinoma |
RGD |
PMID:16568086 |
RGD:150573808 |
NCBI chr16:35,872,301...35,947,097
Ensembl chr16:35,872,131...35,946,987
|
|
G |
MAP3K8 |
mitogen-activated protein kinase kinase kinase 8 |
ameliorates |
ISO |
associated with clear cell renal cell carcinoma |
RGD |
PMID:23982215 |
RGD:151356974 |
NCBI chr10:40,714,004...40,746,390
Ensembl chr10:40,713,847...40,742,462
|
|
G |
MIR423 |
microRNA mir-423 |
|
ISO |
human cells in mouse model |
RGD |
PMID:30326930 |
RGD:153344557 |
NCBI chr12:46,211,525...46,211,604
Ensembl chr12:46,211,525...46,211,611
|
|
G |
MIR744 |
microRNA mir-744 |
treatment |
ISO |
associated with nasopharynx carcinoma |
RGD |
PMID:25961434 |
RGD:11056278 |
NCBI chr12:56,464,848...56,464,927
Ensembl chr12:56,464,848...56,464,927
|
|
G |
NF2 |
NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor |
|
ISO |
associated with hepatocellular carcinoma |
RGD |
PMID:26443326 |
RGD:11076529 |
NCBI chr14:46,653,869...46,726,421
Ensembl chr14:46,653,900...46,731,999
|
|
G |
NTRK3 |
neurotrophic receptor tyrosine kinase 3 |
ameliorates |
ISO |
associated with mammary carcinoma |
RGD |
PMID:20802235 |
RGD:150520014 |
NCBI chr 1:191,535,262...191,941,675
Ensembl chr 1:191,535,301...191,925,327
|
|
G |
PAGR1 |
PAXIP1 associated glutamate rich protein 1 |
|
ISO |
human cells in mouse model |
RGD |
PMID:33833989 |
RGD:153344568 |
NCBI chr 3:18,052,679...18,056,920
Ensembl chr 3:18,052,935...18,056,837
|
|
G |
PTPRB |
protein tyrosine phosphatase receptor type B |
treatment |
ISO |
|
RGD |
PMID:23899555 |
RGD:151660352 |
NCBI chr 5:34,656,460...34,794,838
Ensembl chr 5:34,659,964...34,794,289
|
|
G |
RICTOR |
RPTOR independent companion of MTOR complex 2 |
|
ISO |
human cells in mouse model |
RGD |
PMID:20978191 PMID:29809146 |
RGD:152995469 RGD:152995516 |
NCBI chr16:24,109,934...24,250,019
Ensembl chr16:24,109,939...24,311,132
|
|
G |
RPTOR |
regulatory associated protein of MTOR complex 1 |
|
ISO |
|
RGD |
PMID:29809146 |
RGD:152995516 |
NCBI chr12:1,709,121...1,991,844
Ensembl chr12:1,709,128...1,991,574
|
|
G |
SF3B4 |
splicing factor 3b subunit 4 |
|
ISO |
human cells in mouse model |
RGD |
PMID:30391496 |
RGD:155804298 |
NCBI chr 4:99,123,564...99,129,218
Ensembl chr 4:99,123,585...99,129,218
|
|
G |
SOX30 |
SRY-box transcription factor 30 |
ameliorates |
ISO |
|
RGD |
PMID:29739711 |
RGD:151660333 |
NCBI chr16:65,642,107...65,677,693
Ensembl chr16:65,642,223...65,678,047
|
|
G |
SRC |
SRC proto-oncogene, non-receptor tyrosine kinase |
treatment ameliorates |
ISO |
associated with breast cancer; associated with nasopharynx carcinoma; |
RGD |
PMID:15753384 PMID:27078847 |
RGD:150521726 RGD:1581400 |
NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860
|
|
|
G |
ADAM28 |
ADAM metallopeptidase domain 28 |
|
ISO |
associated with breast cancer;DNA:hypermethylation: |
RGD |
PMID:25620615 |
RGD:153298970 |
NCBI chr14:8,375,169...8,438,622
Ensembl chr14:8,375,212...8,438,615
|
|
G |
ADGRB1 |
adhesion G protein-coupled receptor B1 |
disease_progression |
ISO |
associated with stomach cancer; |
RGD |
PMID:11172604 |
RGD:13831357 |
NCBI chr 4:1,582,321...1,658,639
Ensembl chr 4:1,582,330...1,647,573
|
|
G |
AICDA |
activation induced cytidine deaminase |
|
ISO |
associated with stomach cancer;protein:increased expression:stomach (human) |
RGD |
PMID:21538122 |
RGD:127285638 |
NCBI chr 5:62,777,236...62,787,342
Ensembl chr 5:62,777,352...62,787,369
|
|
G |
ANGPTL4 |
angiopoietin like 4 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:17130448 |
|
NCBI chr 2:70,905,767...70,912,892
Ensembl chr 2:70,904,531...70,912,974
|
|
G |
ANXA1 |
annexin A1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19381893 |
|
NCBI chr 1:226,414,200...226,431,963
Ensembl chr 1:226,414,306...226,432,279
|
|
G |
AQP3 |
aquaporin 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21401805 |
|
NCBI chr10:33,045,374...33,050,285
Ensembl chr10:33,045,245...33,051,082
|
|
G |
ARHGAP5 |
Rho GTPase activating protein 5 |
|
ISO |
associated with nasopharynx carcinoma;mRNA, protein:increased expression: epithelium of nasopharynx |
RGD |
PMID:25961434 |
RGD:11056278 |
NCBI chr 7:67,494,237...67,631,461
Ensembl chr 7:67,494,941...67,594,197
|
|
G |
ASXL1 |
ASXL transcriptional regulator 1 |
|
ISO |
associated with colorectal cancer |
RGD |
PMID:32317519 |
RGD:126779580 |
NCBI chr17:35,985,978...36,067,122
Ensembl chr17:35,985,535...36,067,119
|
|
G |
AXL |
AXL receptor tyrosine kinase |
|
ISO |
associated Pancreatic Neoplasms |
RGD |
PMID:19252414 |
RGD:2325833 |
NCBI chr 6:49,245,802...49,277,917
Ensembl chr 6:49,245,673...49,277,914
|
|
G |
BAG1 |
BAG cochaperone 1 |
disease_progression |
ISO |
associated with Breast Neoplasms:protein:increased expression:breast |
RGD |
PMID:18430249 |
RGD:2292908 |
NCBI chr10:33,227,530...33,240,731
Ensembl chr10:33,227,338...33,240,724
|
|
G |
BAMBI |
BMP and activin membrane bound inhibitor |
|
ISO |
associated with stomach cancer; protein:increased expression: : |
RGD |
PMID:24752577 |
RGD:14390158 |
NCBI chr10:40,053,368...40,058,590
Ensembl chr10:40,053,355...40,060,319
|
|
G |
BARHL2 |
BarH like homeobox 2 |
|
ISO |
associated with oral squamous cell carcinoma; mRNA:decreased expression:mouth mucosa |
RGD |
PMID:27542258 |
RGD:14390167 |
NCBI chr 4:126,030,373...126,035,662
Ensembl chr 4:126,029,437...126,036,210
|
|
G |
BCL2 |
BCL2 apoptosis regulator |
|
ISO |
associated with Breast Neoplasms;protein:increased expression:lymph node |
RGD |
PMID:18217456 |
RGD:2293013 |
NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
|
|
G |
BIRC5 |
baculoviral IAP repeat containing 5 |
disease_progression |
ISO |
associated with Breast Neoplasms associated with Cervix Neoplasms;mRNA:splice variant |
RGD |
PMID:17285241 PMID:17877643 |
RGD:2293098 RGD:2293103 |
NCBI chr12:3,747,276...3,755,214
Ensembl chr12:3,747,279...3,755,215
|
|
G |
BRAF |
B-Raf proto-oncogene, serine/threonine kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29426936 |
|
NCBI chr18:8,957,963...9,132,558
Ensembl chr18:8,957,991...9,132,553
|
|
G |
BRD7 |
bromodomain containing 7 |
severity |
ISO |
protein:increased expression:lung: |
RGD |
PMID:22008115 |
RGD:9586442 |
NCBI chr 6:34,478,008...34,519,622
Ensembl chr 6:34,478,012...34,519,663
|
|
G |
BSG |
basigin |
disease_progression |
ISO |
associated with Breast Neoplasms |
RGD |
PMID:16004819 |
RGD:2289055 |
NCBI chr 2:77,735,586...77,743,451
|
|
G |
BTK |
Bruton tyrosine kinase |
disease_progression |
ISO |
associated with lung adenocarcinoma;protein:increased expression:lung (human) |
RGD |
PMID:31200752 |
RGD:151347847 |
NCBI chr X:82,981,512...83,014,475
Ensembl chr X:82,981,515...83,014,573
|
|
G |
CA9 |
carbonic anhydrase 9 |
|
ISO |
associated with Cervix Neoplasms |
RGD |
PMID:17233814 |
RGD:2293196 |
NCBI chr 1:236,393,727...236,400,994
Ensembl chr 1:236,394,306...236,400,822
|
|
G |
CAB39 |
calcium binding protein 39 |
|
ISO |
associated with pancreatic cancer;RNA:increased expression:pancreas |
RGD |
PMID:28197410 |
RGD:14398834 |
NCBI chr15:131,492,575...131,584,963
Ensembl chr15:131,492,578...131,584,962
|
|
G |
CASP9 |
caspase 9 |
|
ISO |
associated with Carcinoma, Non-Small-Cell Lung;DNA:SNP:exon:rs1052576 (human) |
RGD |
PMID:17285546 |
RGD:13434907 |
NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007
|
|
G |
CAV1 |
caveolin 1 |
disease_progression |
ISO |
associated with Melanoma |
RGD |
PMID:22134245 |
RGD:8661767 |
NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465
|
|
G |
CBL |
Cbl proto-oncogene |
|
ISO |
associated with stomach carcinoma;protein:increased expression:stomach |
RGD |
PMID:31611438 |
RGD:126925223 |
NCBI chr 9:46,416,937...46,512,855
Ensembl chr 9:46,416,938...46,512,834
|
|
G |
CBLB |
Cbl proto-oncogene B |
|
ISO |
associated with stomach carcinoma; |
RGD |
PMID:20038312 |
RGD:150540338 |
NCBI chr13:153,480,525...153,700,115
Ensembl chr13:153,395,978...153,700,056
|
|
G |
CCND2 |
cyclin D2 |
|
ISO |
associated with colorectal cancer;protein:increased expression:colorectum |
RGD |
PMID:19508551 |
RGD:151665111 |
NCBI chr 5:66,092,483...66,114,575
Ensembl chr 5:66,087,379...66,114,571
|
|
G |
CCNE1 |
cyclin E1 |
|
ISO |
associated with Carcinoma, Transitional Cell;protein:decreased expression |
RGD |
PMID:16949911 |
RGD:2289266 |
NCBI chr 6:39,919,541...39,933,224
Ensembl chr 6:39,919,624...39,933,363
|
|
G |
CCNH |
cyclin H |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
|
NCBI chr 2:94,980,938...95,019,053
Ensembl chr 2:94,980,941...95,018,634
|
|
G |
CCR5 |
C-C motif chemokine receptor 5 |
|
ISO |
associated with Breast Neoplasms;mRNA:increased expression:lymph node |
RGD |
PMID:24301790 |
RGD:8551816 |
NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,895
|
|
G |
CD274 |
CD274 molecule |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16530813 |
|
NCBI chr 1:216,646,378...216,792,731
Ensembl chr 1:216,660,041...216,792,724
|
|
G |
CD40 |
CD40 molecule |
|
ISO |
associated with breast cancer;DNA:snps:5' utr, intron:c.-1T>C, c.51+914T>G (rs1883832, rs4810485) (human) |
RGD |
PMID:21912605 |
RGD:8547780 |
NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528
|
|
G |
CD44 |
CD44 molecule |
|
ISO |
associated with Breast Neoplasms, Colorectal Neoplasms, Stomach Neoplasms;mRNA, protein:splice variant, increased expression:breast, large intestine, stomach |
RGD |
PMID:16425351 |
RGD:2289356 |
NCBI chr 2:25,788,699...25,884,209
Ensembl chr 2:25,788,703...25,884,153
|
|
G |
CDH1 |
cadherin 1 |
|
ISO |
associated with Cervix Neoplasms associated with Breast Neoplasms |
RGD |
PMID:17649807 PMID:18097581 |
RGD:2289498 RGD:2296046 |
NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986
|
|
G |
CDKN1A |
cyclin dependent kinase inhibitor 1A |
|
ISO |
associated with Oral Squamous Cell Carcinoma; associated with Eyelid Neoplasms; |
RGD |
PMID:15817070 PMID:19628749 |
RGD:8661799 RGD:8662374 |
NCBI chr 7:32,354,776...32,363,771
Ensembl chr 7:32,359,455...32,363,761
|
|
G |
CDKN1B |
cyclin dependent kinase inhibitor 1B |
|
ISO |
associated with non-small cell lung carcinoma associated with Breast Neoplasms |
RGD |
PMID:12015771 PMID:28601655 |
RGD:13673921 RGD:2293607 |
NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831
|
|
G |
CDKN2A |
cyclin dependent kinase inhibitor 2A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29426936 |
|
NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854
|
|
G |
CLDN1 |
claudin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:33665778 |
|
NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
|
|
G |
CLPTM1L |
CLPTM1 like |
|
ISO |
associated with esophagus squamous cell carcinoma; mRNA:increased expression:esophagus |
RGD |
PMID:25480402 |
RGD:150530497 |
NCBI chr16:79,237,000...79,248,503
Ensembl chr16:79,237,061...79,248,500
|
|
G |
CLU |
clusterin |
|
ISO |
associated with breast cancer;DNA:snp:promoter:g.27611345C>G (rs9331888) (human) |
RGD |
PMID:22037783 |
RGD:8963167 |
NCBI chr14:11,336,585...11,352,569
Ensembl chr14:11,336,595...11,349,764
|
|
G |
COMT |
catechol-O-methyltransferase |
|
ISO |
associated with breast cancer;DNA:missense mutation:cds:p.V108/158M (human) |
RGD |
PMID:10755383 |
RGD:8662330 |
NCBI chr14:51,384,729...51,403,997
Ensembl chr14:51,385,738...51,403,998
|
|
G |
CRADD |
CASP2 and RIPK1 domain containing adaptor with death domain |
|
ISO |
associated with Prostatic Neoplasms |
RGD |
PMID:16707422 |
RGD:2298925 |
NCBI chr 5:89,257,603...89,480,414
Ensembl chr 5:89,267,944...89,479,712
|
|
G |
CRP |
C-reactive protein, pentraxin-related |
susceptibility |
ISO |
associated with Breast Neoplasm; DNA:polymorphism: :1846C>T(rs1205)(human) |
RGD |
PMID:24633920 |
RGD:9580226 |
NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,793,350...90,805,218
|
|
G |
CSF1R |
colony stimulating factor 1 receptor |
|
ISO |
associated with Breast Neoplasms |
RGD |
PMID:14734466 |
RGD:2293711 |
NCBI chr 2:151,102,138...151,130,311
Ensembl chr 2:151,102,147...151,147,633
|
|
G |
CTLA4 |
cytotoxic T-lymphocyte associated protein 4 |
|
ISO |
associated with Prostatic Neoplasms |
RGD |
PMID:10611340 |
RGD:4891523 |
NCBI chr15:107,283,081...107,288,041
Ensembl chr15:107,282,927...107,289,103
|
|
G |
CTNNA1 |
catenin alpha 1 |
|
ISO |
associated with Breast Neoplasms |
RGD |
PMID:12047765 |
RGD:2289795 |
NCBI chr 2:140,682,776...140,869,828
Ensembl chr 2:140,682,371...140,871,334
|
|
G |
CTNNB1 |
catenin beta 1 |
|
ISO |
associated with Breast Neoplasms;protein:decreased expression |
RGD |
PMID:17908479 |
RGD:2289813 |
NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311
|
|
G |
CXCL12 |
C-X-C motif chemokine ligand 12 |
disease_progression |
ISO |
associated with stomach cancer;mRNA:increased expression:stomach (human) |
RGD |
PMID:21633638 |
RGD:152023624 |
NCBI chr14:91,516,383...91,543,857
Ensembl chr14:91,516,431...91,552,752
|
|
G |
CXCR4 |
C-X-C motif chemokine receptor 4 |
|
ISO |
associated with nasopharynx carcinoma; protein:increased expression:lymph node (human) |
RGD |
PMID:16000558 |
RGD:151893515 |
NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,232
|
|
G |
CYCS |
cytochrome c, somatic |
|
ISO |
associated with non-small cell lung carcinoma; protein:decreased expression:serum |
RGD |
PMID:25578497 |
RGD:13792769 |
NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866
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|
G |
DDR1 |
discoidin domain receptor tyrosine kinase 1 |
severity |
ISO |
mRNA, protein:increased expression:mouth (human) mRNA:increased expression:kidney, lymph nodes (human) |
RGD |
PMID:27020590 PMID:31253192 |
RGD:151347620 RGD:151347863 |
NCBI chr 7:23,371,358...23,391,585
Ensembl chr 7:23,373,845...23,391,584
|
|
G |
DDR2 |
discoidin domain receptor tyrosine kinase 2 |
disease_progression |
ISO |
associated with oral squamous cell carcinoma |
RGD |
PMID:29945346 |
RGD:150429700 |
NCBI chr 4:87,749,738...87,911,818
Ensembl chr 4:87,756,168...87,911,296
|
|
G |
DNMT3B |
DNA methyltransferase 3 beta |
|
ISO |
associated with Carcinoma, Pancreatic Ductal; |
RGD |
PMID:22919364 |
RGD:9589121 |
NCBI chr17:36,345,715...36,386,076
Ensembl chr17:36,345,816...36,386,072
|
|
G |
EBAG9 |
estrogen receptor binding site associated antigen 9 |
|
ISO |
associated with Breast Neoplasms;protein:increased expression:breast associated with Prostatic Neoplasm;protein:increased expression:prostate gland, lymph node |
RGD |
PMID:12054692 PMID:12845666 PMID:17187007 |
RGD:2289847 RGD:2289856 RGD:2298489 |
NCBI chr 4:27,986,270...28,013,970
Ensembl chr 4:27,986,866...28,013,945
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|
G |
EGFR |
epidermal growth factor receptor |
treatment |
ISO |
associated with Squamous Cell Carcinoma of the Tongue |
RGD |
PMID:19380367 |
RGD:8551769 |
NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589
|
|
G |
EHMT2 |
euchromatic histone lysine methyltransferase 2 |
|
ISO |
associated with Esophageal Squamous Cell Carcinoma; associated with Melanoma; |
RGD |
PMID:24658378 PMID:24805087 |
RGD:9590069 RGD:9590071 |
NCBI chr 7:23,977,683...23,992,673
Ensembl chr 7:23,977,683...23,993,478
|
|
G |
EPHA2 |
EPH receptor A2 |
|
ISO |
protein:increased expression:esophagus (human) |
RGD |
PMID:33833989 |
RGD:153344568 |
NCBI chr 6:75,251,465...75,279,364
Ensembl chr 6:75,251,467...75,279,314
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|
G |
ERBB2 |
erb-b2 receptor tyrosine kinase 2 |
disease_progression |
ISO |
associated with Breast Neoplasms;DNA, protein:polymorphism, increased expression:serum:p.I655V associated with lung adenocarcinoma; protein:increased expression:lung (human) associated with Carcinoma, Transitional Cell;protein:increased expression:urinary bladder CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:18097576 PMID:18237248 PMID:21532492 PMID:21966491 |
RGD:153344600 RGD:2289925 RGD:2289926 |
NCBI chr12:22,591,621...22,621,384
Ensembl chr12:22,590,725...22,621,351
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|
G |
ERBB3 |
erb-b2 receptor tyrosine kinase 3 |
|
ISO |
associated with Prostatic Neoplasms;protein:increased expression, altered localization:lymph node, nucleus associated with head and neck squamous cell carcinoma |
RGD |
PMID:17634423 PMID:20604875 |
RGD:126790467 RGD:2289944 |
NCBI chr 5:21,474,218...21,495,040
Ensembl chr 5:21,474,475...21,495,038
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|
G |
ERBB4 |
erb-b2 receptor tyrosine kinase 4 |
severity disease_progression |
ISO |
associated with colorectal adenocarcinoma associated with lung non-small cell carcinoma associated with oral squamous cell carcinoma |
RGD |
PMID:16507107 PMID:21324275 PMID:27444519 |
RGD:126781762 RGD:126781766 RGD:126790471 |
NCBI chr15:113,966,573...115,096,984
Ensembl chr15:113,974,437...115,096,565
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|
G |
FAS |
Fas cell surface death receptor |
susceptibility |
ISO |
associated with Cervix Neoplasms;DNA:polymorphism:promoter:-1377G>A |
RGD |
PMID:18068525 |
RGD:2298509 |
NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716
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|
G |
FGF1 |
fibroblast growth factor 1 |
|
ISO |
associated with Cervix Neoplasms;mRNA:increased expression:lymph node |
RGD |
PMID:17242701 |
RGD:2290286 |
NCBI chr 2:144,133,846...144,241,345
Ensembl chr 2:144,133,392...144,241,323
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|
G |
FGFR2 |
fibroblast growth factor receptor 2 |
|
ISO |
associated with breast cancer;DNA:snp:intron:c.109+7033T>A (rs1219648) (human) |
RGD |
PMID:20640597 |
RGD:7394846 |
NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425
|
|
G |
FLT3 |
fms related receptor tyrosine kinase 3 |
disease_progression |
ISO |
associated with Prostatic Neoplasms |
RGD |
PMID:14566827 |
RGD:2302210 |
NCBI chr11:5,370,475...5,455,439
Ensembl chr11:5,370,496...5,455,358
|
|
G |
FOXA1 |
forkhead box A1 |
|
ISO |
associated with lung non-small cell carcinoma; mRNA:increased expression: : |
RGD |
PMID:29115441 |
RGD:151665751 |
NCBI chr 7:62,471,233...62,479,638
Ensembl chr 7:62,471,249...62,479,220
|
|
G |
FOXP1 |
forkhead box P1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25485836 |
|
NCBI chr13:52,346,844...52,974,358
Ensembl chr13:52,348,234...52,876,892
|
|
G |
GPX3 |
glutathione peroxidase 3 |
|
ISO |
associated with stomach carcinoma; DNA:hypermethylation:promoter |
RGD |
PMID:23071548 |
RGD:151665353 |
NCBI chr16:71,980,467...71,989,011
Ensembl chr16:71,980,475...71,989,026
|
|
G |
GRIK2 |
glutamate ionotropic receptor kainate type subunit 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
|
NCBI chr 1:68,052,086...68,680,448
Ensembl chr 1:68,057,538...68,679,256
|
|
G |
HMGB1 |
high mobility group box 1 |
|
ISO |
associated with Adenocarcinoma, Colon |
RGD |
PMID:20616616 |
RGD:10402080 |
NCBI chr11:7,195,556...7,321,071
|
|
G |
ICAM1 |
intercellular adhesion molecule 1 |
|
ISO |
associated with Breast Neoplasms |
RGD |
PMID:21590495 |
RGD:8547712 |
NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
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|
G |
IER2 |
immediate early response 2 |
|
ISO |
|
RGD |
PMID:22120713 |
RGD:153323322 |
NCBI chr 2:65,909,638...65,912,491
Ensembl chr 2:65,909,651...65,912,445
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|
G |
IL13 |
interleukin 13 |
|
ISO |
associated with Melanoma, Cutaneous Malignant;mRNA:increased expression:lymph node |
RGD |
PMID:17545514 |
RGD:8549587 |
NCBI chr 2:134,972,099...134,976,672
Ensembl chr 2:134,972,623...134,975,093
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|
G |
IL18 |
interleukin 18 |
|
ISO |
associated with Breast Neoplasms;protein:increased expression:serum |
RGD |
PMID:12902898 |
RGD:8655867 |
NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219
|
|
G |
ING4 |
inhibitor of growth family member 4 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:27806345 |
|
NCBI chr 5:64,027,789...64,036,671
Ensembl chr 5:64,027,855...64,036,773
|
|
G |
IQSEC1 |
IQ motif and Sec7 domain ArfGEF 1 |
disease_progression |
ISO |
associated with lung adenocarcinoma; protein:increased expression:lung (human) |
RGD |
PMID:21966491 |
RGD:153344600 |
NCBI chr13:71,203,967...71,366,685
Ensembl chr13:71,031,001...71,366,684
|
|
G |
ITGB1 |
integrin subunit beta 1 |
|
ISO |
associated with non-small cell lung carcinoma, |
RGD |
PMID:28537888 |
RGD:13792830 |
NCBI chr10:56,078,393...56,130,608
Ensembl chr10:56,078,396...56,173,326
|
|
G |
KCNJ12 |
potassium inwardly rectifying channel subfamily J member 12 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34755307 |
|
NCBI chr12:61,424,459...61,511,373
Ensembl chr12:61,506,577...61,507,870
|
|
G |
KDR |
kinase insert domain receptor |
treatment |
ISO |
associated with Squamous Cell Carcinoma of the Tongue |
RGD |
PMID:19380367 |
RGD:8551769 |
NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,122...41,856,336
|
|
G |
KLF7 |
KLF transcription factor 7 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:37734194 |
|
NCBI chr15:110,282,399...110,380,165
Ensembl chr15:110,286,463...110,379,305
|
|
G |
KMT2D |
lysine methyltransferase 2D |
|
ISO |
associated with stomach cancer |
RGD |
PMID:30177394 |
RGD:150521710 |
NCBI chr 5:15,049,827...15,091,622
|
|
G |
LAMC2 |
laminin subunit gamma 2 |
|
ISO |
associated with lung squamous cell carcinoma; |
RGD |
PMID:23124251 |
RGD:13793371 |
NCBI chr 9:124,427,545...124,499,672
Ensembl chr 9:124,435,807...124,495,351
|
|
G |
LOC100514786 |
ATP-binding cassette sub-family A member 13 |
susceptibility |
ISO |
DNA:amplification:cds: (human, male) |
RGD |
PMID:27366209 |
RGD:152995256 |
NCBI chr 9:135,104,047...135,452,477
Ensembl chr 9:135,115,078...135,451,812
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|
G |
LOC100524016 |
mesothelin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22644300 |
|
NCBI chr 3:41,025,892...41,029,302
|
|
G |
LOC100737875 |
solute carrier family 22 member 10-like |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
|
NCBI chr 2:8,734,036...8,750,828
|
|
G |
LRRC59 |
leucine rich repeat containing 59 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
|
NCBI chr12:26,678,207...26,694,277
Ensembl chr12:26,677,226...26,694,279
|
|
G |
MACIR |
macrophage immunometabolism regulator |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
|
NCBI chr 2:108,733,347...108,753,276
Ensembl chr 2:108,733,357...108,753,275
|
|
G |
MET |
MET proto-oncogene, receptor tyrosine kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29426936 |
|
NCBI chr18:29,426,044...29,541,526
Ensembl chr18:29,426,048...29,541,512
|
|
G |
MIR125A |
microRNA mir-125a |
|
ISO |
associated with stomach cancer; |
RGD |
PMID:22322911 |
RGD:21408544 |
NCBI chr 6:58,331,566...58,331,645
Ensembl chr 6:58,331,566...58,331,645
|
|
G |
MIR152 |
microRNA mir-152 |
|
ISO |
associated with breast cancer |
RGD |
PMID:22935141 |
RGD:19165152 |
NCBI chr12:24,292,249...24,292,328
Ensembl chr12:24,292,251...24,292,336
|
|
G |
MIR155 |
microRNA mir-155 |
disease_progression |
ISO |
associated with colon cancer |
RGD |
PMID:26885061 PMID:27856635 PMID:29893326 |
RGD:21079444 RGD:21079446 RGD:21409756 |
NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902
|
|
G |
MIR187 |
microRNA mir-187 |
|
ISO |
associated with oral squamous cell carcinoma; RNA:increased expression:plasma |
RGD |
PMID:27542258 |
RGD:14390167 |
NCBI chr 6:119,674,881...119,674,958
|
|
G |
MIR224 |
microRNA mir-224 |
|
ISO |
associated with colorectal cancer; mRNA:decreased expression:colorectal mucosa: |
RGD |
PMID:25919696 |
RGD:14398749 |
NCBI chr X:123,283,427...123,283,507
Ensembl chr X:123,283,427...123,283,507
|
|
G |
MIR30A |
microRNA mir-30a |
|
ISO |
associated with Colorectal Neoplasms |
RGD |
PMID:23486085 |
RGD:13432035 |
NCBI chr 1:51,412,827...51,412,933
Ensembl chr 1:51,412,827...51,412,933
|
|
G |
MIR335 |
microRNA mir-335 |
|
ISO |
associated with stomach cancer; RNA:decreased expression:stomach |
RGD |
PMID:21822301 |
RGD:14394425 |
NCBI chr18:18,341,580...18,341,659
Ensembl chr18:18,341,568...18,341,659
|
|
G |
MIR432 |
microRNA mir-432 |
disease_progression |
ISO |
mRNA:decreased expression:colon (human) |
RGD |
PMID:33717244 |
RGD:152999433 |
NCBI chr 7:121,711,137...121,711,216
Ensembl chr 7:121,711,137...121,711,216
|
|
G |
MMP2 |
matrix metallopeptidase 2 |
disease_progression |
ISO |
associated with Tongue Neoplasms associated with Carcinoma, Ductal, Breast |
RGD |
PMID:23107277 PMID:23280016 |
RGD:8547824 RGD:8655998 |
NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982
|
|
G |
MMP3 |
matrix metallopeptidase 3 |
|
ISO |
associated with breast cancer;DNA:deletion:promoter:-1170_-1172delA (human) |
RGD |
PMID:15161710 |
RGD:8662937 |
NCBI chr 9:33,446,969...33,453,995
Ensembl chr 9:33,446,836...33,454,000
|
|
G |
MMP9 |
matrix metallopeptidase 9 |
disease_progression |
ISO |
associated with Tongue Neoplasms associated with Endometrial Neoplasms;protein:increased expression:endometrium associated with Carcinoma, Non-Small-Cell Lung;protein:increased expression:serum |
RGD |
PMID:12487935 PMID:20704821 PMID:23107277 |
RGD:2298523 RGD:5129215 RGD:8547824 |
NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788
|
|
G |
MSH2 |
mutS homolog 2 |
|
ISO |
associated with laryngeal squamous cell carcinoma |
RGD |
PMID:24459922 |
RGD:126848797 |
NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,585
|
|
G |
MT1A |
metallothionein 1A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17418620 |
|
NCBI chr 6:18,672,016...18,673,673
Ensembl chr 6:18,672,001...18,673,672
|
|
G |
MTA1 |
metastasis associated 1 |
|
ISO |
associated with Carcinoma, Non-Small-Cell Lung;mRNA:increased expression:lung |
RGD |
PMID:11804687 |
RGD:9588220 |
|
|
G |
MTOR |
mechanistic target of rapamycin kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
|
NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
|
|
G |
MUC1 |
mucin 1, cell surface associated |
|
ISO |
associated with Esophageal Neoplasms associated with Common Bile Duct Neoplasms associated with Gallbladder Neoplasms;protein:altered localization:gallbladder associated with Carcinoma, Renal Cell; |
RGD |
PMID:10390012 PMID:11295067 PMID:16222735 PMID:21339746 |
RGD:2324649 RGD:2324860 RGD:7245968 RGD:7349383 |
NCBI chr 4:94,626,317...94,631,194
|
|
G |
MUC5AC |
mucin 5AC, oligomeric mucus/gel-forming |
|
ISO |
associated with chloangiocarcinoma;protein:increased expression:bile duct |
RGD |
PMID:16842244 |
RGD:2325168 |
NCBI chr 2:757,897...790,321
|
|
G |
NCAM1 |
neural cell adhesion molecule 1 |
|
ISO |
|
RGD |
PMID:10086383 |
RGD:2326067 |
NCBI chr 9:40,628,602...40,960,605
Ensembl chr 9:40,628,631...40,960,591
|
|
G |
NME1 |
NME/NM23 nucleoside diphosphate kinase 1 |
|
ISO |
associated with Breast Neoplasms associated with Cervix Neoplasms; associated with Endometrial Neoplasms |
RGD |
PMID:8102131 PMID:8855975 PMID:9036878 |
RGD:2299061 RGD:2299062 RGD:2299077 |
NCBI chr12:27,416,308...27,435,044
Ensembl chr12:27,416,346...27,436,140
|
|
G |
NME2 |
NME/NM23 nucleoside diphosphate kinase 2 |
|
ISO |
associated with Cervix Neoplasms; associated with Endometrial Neoplasms |
RGD |
PMID:8855975 |
RGD:2299062 |
NCBI chr12:27,439,529...27,445,025
Ensembl chr12:27,439,260...27,445,027
|
|
G |
NOS3 |
nitric oxide synthase 3 |
susceptibility |
ISO |
associated with Breast Neoplasms;DNA:polymorphisms:promoter, exon:-786T>C,p.E298D (human) |
RGD |
PMID:17262178 |
RGD:2292070 |
NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943
|
|
G |
OGG1 |
8-oxoguanine DNA glycosylase |
|
ISO |
associated with breast cancer;DNA:missense mutation:cds:p.S326C (rs1052133) (human) |
RGD |
PMID:18977234 |
RGD:8657156 |
NCBI chr13:66,038,669...66,045,478
|
|
G |
PAGR1 |
PAXIP1 associated glutamate rich protein 1 |
disease_progression |
ISO |
protein:decreased expression:esophagus (human) |
RGD |
PMID:33833989 |
RGD:153344568 |
NCBI chr 3:18,052,679...18,056,920
Ensembl chr 3:18,052,935...18,056,837
|
|
G |
PDGFA |
platelet derived growth factor subunit A |
|
ISO |
associated with Breast Neoplasms;mRNA:increased expression:breast |
RGD |
PMID:8619189 |
RGD:2292155 |
NCBI chr 3:296,399...322,967
Ensembl chr 3:301,584...321,712
|
|
G |
PDGFB |
platelet derived growth factor subunit B |
|
ISO |
associated with Breast Neoplasms;mRNA:increased expression:lymph node |
RGD |
PMID:17674348 |
RGD:2292173 |
Ensembl chr 5:8,986,462...9,007,435
|
|
G |
PDPK1 |
3-phosphoinositide dependent protein kinase 1 |
|
ISO |
associated with non-small cell lung carcinoma;mRNA:increased expression:blood serum |
RGD |
PMID:25064732 |
RGD:13503320 |
NCBI chr 3:39,429,928...39,512,623
Ensembl chr 3:39,432,058...39,512,601
|
|
G |
PDPN |
podoplanin |
|
ISO |
associated with Breast Neoplasms associated with Cervix Neoplasms |
RGD |
PMID:16528371 PMID:18165897 |
RGD:2292231 RGD:2292237 |
NCBI chr 6:73,019,063...73,050,000
Ensembl chr 6:73,019,057...73,049,996
|
|
G |
PEBP1 |
phosphatidylethanolamine binding protein 1 |
|
ISO |
associated with Cervix Neoplasms associated with Breast Neoplasms |
RGD |
PMID:16243812 PMID:18191186 |
RGD:2302867 RGD:2302868 |
NCBI chr14:34,523,901...34,530,238
|
|
G |
PIK3CA |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
|
ISO |
associated with Colorectal Neoplasms |
RGD |
PMID:25550888 |
RGD:13432030 |
NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,274,587
|
|
G |
PIK3CB |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
|
ISO |
associated with Colorectal Neoplasms |
RGD |
PMID:25550888 |
RGD:13432030 |
NCBI chr13:79,427,033...79,610,840
Ensembl chr13:79,425,835...79,610,840
|
|
G |
PIP5K1A |
phosphatidylinositol-4-phosphate 5-kinase type 1 alpha |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34755307 |
|
NCBI chr 4:98,012,941...98,062,166
Ensembl chr 4:98,012,945...98,056,815
|
|
G |
POU5F1 |
POU class 5 homeobox 1 |
|
ISO |
associated with Seminoma; associated with Carcinoma, Embryonal |
RGD |
PMID:15386301 |
RGD:2292442 |
NCBI chr 7:23,564,654...23,570,691
|
|
G |
PPARG |
peroxisome proliferator activated receptor gamma |
|
ISO |
associated with Cholangiocarcinoma;protein:increased expression:bile duct epithelium |
RGD |
PMID:20021832 |
RGD:2317459 |
NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944
|
|
G |
PREX1 |
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 |
|
ISO |
associated with Prostatic Neoplasms |
RGD |
PMID:19305425 |
RGD:2314605 |
NCBI chr17:50,352,273...50,550,402
Ensembl chr17:50,354,775...50,550,637
|
|
G |
PTEN |
phosphatase and tensin homolog |
|
ISO |
associated with Breast Neoplasms associated with Prostatic Neoplasms;protein:decreased expression:prostate |
RGD |
PMID:17163422 PMID:17919877 |
RGD:2292499 RGD:2292507 |
NCBI chr14:99,929,590...100,021,619
|
|
G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
|
ISO |
associated with Biliary Tract Neoplasms associated with Breast Neoplasms associated with carcinoma, non-small-cell lung; DNA:SNP: :929G>C(human) |
RGD |
PMID:18159174 PMID:18353210 PMID:20016751 |
RGD:2300128 RGD:2317165 RGD:5135471 |
NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
|
|
G |
PTK2 |
protein tyrosine kinase 2 |
|
ISO |
associated with lung squamous cell carcinoma; protein:increased tyrosine phosphorylation:lymph node |
RGD |
PMID:23906871 |
RGD:152176664 |
NCBI chr 4:2,656,606...2,896,060
Ensembl chr 4:2,656,614...2,896,054
|
|
G |
PTPN13 |
protein tyrosine phosphatase non-receptor type 13 |
|
ISO |
associated with lung squamous cell carcinoma; protein:decreased expression:lymph node |
RGD |
PMID:23906871 |
RGD:152176664 |
NCBI chr 8:132,035,170...132,200,425
Ensembl chr 8:132,035,151...132,249,411
|
|
G |
RAMP2 |
receptor activity modifying protein 2 |
disease_progression |
ISO |
associated with colorectal cancer; protein:increased expression:lymph node (human) |
RGD |
PMID:23634287 |
RGD:151708733 |
NCBI chr12:20,092,204...20,094,426
Ensembl chr12:20,092,196...20,094,469
|
|
G |
RAMP3 |
receptor activity modifying protein 3 |
|
ISO |
associated with colorectal cancer; protein:increased expression:lymph node (human) |
RGD |
PMID:23634287 |
RGD:151708733 |
NCBI chr18:50,319,795...50,366,757
Ensembl chr18:50,319,797...50,366,739
|
|
G |
RASSF2 |
Ras association domain family member 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17013896 |
|
NCBI chr17:13,773,289...13,822,729
Ensembl chr17:13,773,292...13,822,206
|
|
G |
RBM10 |
RNA binding motif protein 10 |
|
ISO |
associated with lung adenocarcinoma;DNA:missense mutation:exon:p.R241C (c.763C>T) (human) |
RGD |
PMID:30405763 |
RGD:151356993 |
NCBI chr X:41,773,232...41,803,656
Ensembl chr X:41,773,232...41,803,653
|
|
G |
RELA |
RELA proto-oncogene, NF-kB subunit |
|
ISO |
associated with Prostatic Neoplasms;protein:altered localization:nucleus, prostate gland |
RGD |
PMID:17020979 |
RGD:2298757 |
NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469
|
|
G |
RET |
ret proto-oncogene |
|
ISO |
associated with Pancreatic Neoplasms |
RGD |
PMID:18652760 |
RGD:2324925 |
NCBI chr14:61,305,818...61,361,416
Ensembl chr14:61,305,841...61,361,412
|
|
G |
RHOA |
ras homolog family member A |
|
ISO |
associated with Bladder Neoplasms;protein:increased expression:lymph node associated with colorectal cancer |
RGD |
PMID:12855641 PMID:17597401 |
RGD:13432052 RGD:2298872 |
NCBI chr13:31,918,484...31,991,207
Ensembl chr13:31,918,834...31,986,607
|
|
G |
RICTOR |
RPTOR independent companion of MTOR complex 2 |
|
ISO |
associated with breast ductal carcinoma; protein:increased expression:breast tumor, lymph node (human) |
RGD |
PMID:20978191 |
RGD:152995469 |
NCBI chr16:24,109,934...24,250,019
Ensembl chr16:24,109,939...24,311,132
|
|
G |
RUNX1 |
RUNX family transcription factor 1 |
|
ISO |
associated with Carcinoid Tumor |
RGD |
PMID:21636701 |
RGD:126779567 |
NCBI chr13:198,371,835...198,635,648
Ensembl chr13:198,371,837...198,638,189
|
|
G |
SFN |
stratifin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19381893 |
|
NCBI chr 6:84,188,521...84,189,824
Ensembl chr 6:84,188,445...84,189,827
|
|
G |
SKP2 |
S-phase kinase associated protein 2 |
|
ISO |
associated with Endometrial Neoplasms;protein:increased expression:endometrium |
RGD |
PMID:16080017 |
RGD:2315043 |
NCBI chr16:21,463,270...21,500,925
Ensembl chr16:21,463,012...21,509,310
|
|
G |
SLC7A5 |
solute carrier family 7 member 5 |
severity |
ISO |
associated with gastric adenocarcinoma;protein:increased expression: : associated with stomach carcinoma |
RGD |
PMID:21501294 PMID:25908107 |
RGD:11052781 RGD:151361203 |
NCBI chr 6:1,545,940...1,574,298
Ensembl chr 6:1,545,944...1,574,285
|
|
G |
SMAD4 |
SMAD family member 4 |
|
ISO |
associated with Breast Neoplasms |
RGD |
PMID:11809701 |
RGD:2300007 |
NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,589,850...100,628,029
|
|
G |
SMO |
smoothened, frizzled class receptor |
|
ISO |
associated with colorectal cancer |
RGD |
PMID:30784110 |
RGD:150520177 |
NCBI chr18:19,450,730...19,478,796
Ensembl chr18:19,450,743...19,478,898
|
|
G |
SNCG |
synuclein gamma |
|
ISO |
|
RGD |
PMID:15221989 |
RGD:6478801 |
NCBI chr14:87,916,353...87,922,111
Ensembl chr14:87,904,659...87,922,095
|
|
G |
SOCS3 |
suppressor of cytokine signaling 3 |
|
ISO |
associated with Breast Neoplasms |
RGD |
PMID:18097573 |
RGD:2298901 |
NCBI chr12:3,643,832...3,647,015
Ensembl chr12:3,643,929...3,647,009
|
|
G |
SOD2 |
superoxide dismutase 2 |
disease_progression |
ISO |
associated with tongue neoplasms; CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:10853026 PMID:19381893 PMID:20618948 |
RGD:8547519 |
NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
|
|
G |
SOX2 |
SRY-box transcription factor 2 |
disease_progression |
ISO |
associated with Breast Neoplasms |
RGD |
PMID:24382260 |
RGD:8661670 |
NCBI chr13:119,668,476...119,669,435
Ensembl chr13:119,668,476...119,669,435
|
|
G |
SRC |
SRC proto-oncogene, non-receptor tyrosine kinase |
|
ISO |
associated with colon adenocarcinoma, |
RGD |
PMID:21282564 |
RGD:150520218 |
NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860
|
|
G |
ST14 |
ST14 transmembrane serine protease matriptase |
|
ISO |
associated with Endometrial Neoplasms |
RGD |
PMID:19443387 |
RGD:2315087 |
NCBI chr 9:56,888,246...56,929,771
Ensembl chr 9:56,888,246...56,929,767
|
|
G |
STAT3 |
signal transducer and activator of transcription 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21549414 |
|
NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992
|
|
G |
STK11 |
serine/threonine kinase 11 |
|
ISO |
associated with Breast Neoplasms;protein:decreased expression |
RGD |
PMID:12114407 |
RGD:2291948 |
NCBI chr 2:77,229,888...77,249,322
Ensembl chr 2:77,230,372...77,249,327
|
|
G |
TERT |
telomerase reverse transcriptase |
disease_progression |
ISO |
associated with lung non-small cell carcinoma; |
RGD |
PMID:11679180 |
RGD:152977755 |
NCBI chr16:79,258,591...79,276,421
Ensembl chr16:79,258,591...79,276,421
|
|
G |
TIMP1 |
TIMP metallopeptidase inhibitor 1 |
|
ISO |
associated with Endometrial Neoplasms;protein:increased expression:endometrium |
RGD |
PMID:12487935 |
RGD:2298523 |
NCBI chr X:42,103,251...42,106,289
Ensembl chr X:42,102,172...42,106,296
|
|
G |
TIMP3 |
TIMP metallopeptidase inhibitor 3 |
|
ISO |
associated with Breast Neoplasms;mRNA:increased expression:breast |
RGD |
PMID:12828172 |
RGD:2290437 |
NCBI chr 5:12,185,816...12,242,599
Ensembl chr 5:12,185,818...12,242,581
|
|
G |
TIMP4 |
TIMP metallopeptidase inhibitor 4 |
|
ISO |
associated with Breast Neoplasms;mRNA:increased expression:breast |
RGD |
PMID:12828172 |
RGD:2290437 |
NCBI chr13:68,179,803...68,191,199
Ensembl chr13:68,179,806...68,190,942
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|
G |
TLR4 |
toll like receptor 4 |
|
ISO |
associated with Carcinoma, Ductal, Breast; |
RGD |
PMID:23338716 |
RGD:7794684 |
NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970
|
|
G |
TP53 |
tumor protein p53 |
|
ISO |
associated with Penile Neoplasms associated with Carcinoma, Squamous Cell; associated with Breast Neoplasms;DNA:missense mutation, duplication:cds, intron:p.R72P |
RGD |
PMID:18059331 PMID:18230179 PMID:18268397 |
RGD:2290533 RGD:2290534 RGD:8547790 |
NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
|
|
G |
TP53BP1 |
tumor protein p53 binding protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
|
NCBI chr 1:127,958,500...128,032,370
Ensembl chr 1:127,959,213...128,028,712
|
|
G |
TRMT11 |
tRNA methyltransferase 11 homolog |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30705370 |
|
NCBI chr 1:36,930,857...37,002,079
Ensembl chr 1:36,940,334...37,002,056
|
|
G |
TSC2 |
TSC complex subunit 2 |
|
ISO |
associated with Breast Neoplasms |
RGD |
PMID:15951164 |
RGD:11568707 |
NCBI chr 3:39,898,924...39,935,579
Ensembl chr 3:39,898,925...39,937,371
|
|
G |
TSHR |
thyroid stimulating hormone receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:9062474 |
|
NCBI chr 7:103,768,260...103,925,777
Ensembl chr 7:103,768,296...103,925,922
|
|
G |
TTR |
transthyretin |
|
ISO |
associated with colorectal cancer;protein:decreased expresion:blood serum (human) |
RGD |
PMID:21074777 |
RGD:151665155 |
NCBI chr 6:115,496,338...115,503,974
Ensembl chr 6:115,496,326...115,503,977
|
|
G |
VEGFA |
vascular endothelial growth factor A |
|
ISO |
associated with Breast neoplasms; associated with Cervix Neoplasms |
RGD |
PMID:17597103 PMID:19783962 |
RGD:2315454 RGD:7421574 |
NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366
|
|
G |
VEGFC |
vascular endothelial growth factor C |
exacerbates disease_progression |
ISO |
associated with Prostatic Neoplasms associated with pancreatic adenocarcinoma;protein:increased expression:pancreas (human) associated with Lymphatic Metastasis; associated with Breast Neoplasms associated with thyroid diseases;mRNA:increased expression:thyroid gland: associated with Carcinoma, Transitional Cell;protein:increased expression:urinary bladder associated with Cervix Neoplasms |
RGD |
PMID:12203051 PMID:15289890 PMID:17034609 PMID:18061373 PMID:19589137 PMID:19608016 PMID:19923084 More...
|
RGD:155630642 RGD:2315469 RGD:2315474 RGD:2315475 RGD:2315484 RGD:7483611 RGD:7488946 |
NCBI chr15:39,037,764...39,136,234
Ensembl chr15:39,039,311...39,132,936
|
|
G |
VEGFD |
vascular endothelial growth factor D |
|
ISO |
associated with Cervix Neoplasms associated with Breast Neoplasms |
RGD |
PMID:17951197 PMID:19589137 |
RGD:2315475 RGD:2315480 |
NCBI chr X:11,893,254...11,933,923
Ensembl chr X:11,893,259...11,933,809
|
|
G |
WRAP53 |
WD repeat containing antisense to TP53 |
|
ISO |
associated with esophagus squamous cell carcinoma; associated with lung non-small cell carcinoma; |
RGD |
PMID:24626331 PMID:31281482 |
RGD:21081513 RGD:21081532 |
NCBI chr12:52,954,674...52,968,371
Ensembl chr12:52,954,669...52,968,364
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|
|
G |
ACO1 |
aconitase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20390345 |
|
NCBI chr10:33,937,833...34,001,895
Ensembl chr10:33,937,833...34,001,900
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|
G |
ACTB |
actin beta |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15654357 |
|
NCBI chr 3:4,084,275...4,090,383
Ensembl chr 3:4,082,216...4,090,356
|
|
G |
ADAMTS1 |
ADAM metallopeptidase with thrombospondin type 1 motif 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23289900 |
|
NCBI chr13:190,277,175...190,285,957
Ensembl chr13:190,276,430...190,286,214
|
|
G |
AHNAK |
AHNAK nucleoprotein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20388789 |
|
NCBI chr 2:9,186,984...9,216,450
|
|
G |
AHR |
aryl hydrocarbon receptor |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:25826687 PMID:27752740 |
|
NCBI chr 9:86,511,866...86,555,950
Ensembl chr 9:86,511,369...86,555,943
|
|
G |
ALDOA |
aldolase, fructose-bisphosphate A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15654357 |
|
NCBI chr 3:18,246,036...18,260,167
Ensembl chr 3:18,253,384...18,260,163
|
|
G |
ALKBH8 |
alkB homolog 8, tRNA methyltransferase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27811057 |
|
NCBI chr 9:36,077,004...36,119,936
Ensembl chr 9:36,077,192...36,119,920
|
|
G |
ALOX5 |
arachidonate 5-lipoxygenase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20061081 |
|
NCBI chr14:90,859,209...90,907,084
Ensembl chr14:90,859,016...90,907,094
|
|
G |
AMBP |
alpha-1-microglobulin/bikunin precursor |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:14644129 |
|
NCBI chr 1:254,683,885...254,703,220
Ensembl chr 1:254,683,891...254,703,225
|
|
G |
AMOTL1 |
angiomotin like 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34480788 |
|
NCBI chr 9:26,811,872...26,978,107
Ensembl chr 9:26,864,312...26,973,552
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|
G |
ANGPT1 |
angiopoietin 1 |
|
ISO |
associated with Mammary Neoplasms, Animal;mRNA:increased expression:mammary gland |
RGD |
PMID:15459484 |
RGD:1626167 |
NCBI chr 4:29,925,203...30,233,434
Ensembl chr 4:29,933,135...30,233,960
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|
G |
ANGPTL4 |
angiopoietin like 4 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:17130448 |
|
NCBI chr 2:70,905,767...70,912,892
Ensembl chr 2:70,904,531...70,912,974
|
|
G |
ANXA1 |
annexin A1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15654357 |
|
NCBI chr 1:226,414,200...226,431,963
Ensembl chr 1:226,414,306...226,432,279
|
|
G |
ANXA2 |
annexin A2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15654357 |
|
NCBI chr 1:111,588,721...111,635,064
Ensembl chr 1:111,588,306...111,635,059
|
|
G |
ARF1 |
ADP ribosylation factor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27517156 |
|
NCBI chr 2:51,219,597...51,237,640
Ensembl chr 2:51,219,667...51,237,639
|
|
G |
AXL |
AXL receptor tyrosine kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26206560 |
|
NCBI chr 6:49,245,802...49,277,917
Ensembl chr 6:49,245,673...49,277,914
|
|
G |
BCAR1 |
BCAR1 scaffold protein, Cas family member |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21291860 |
|
NCBI chr 6:12,369,332...12,404,822
Ensembl chr 6:12,367,758...12,404,818
|
|
G |
BRMS1 |
BRMS1 transcriptional repressor and anoikis regulator |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:27501413 |
|
NCBI chr 2:6,046,077...6,053,672
Ensembl chr 2:6,046,098...6,053,667
|
|
G |
BSG |
basigin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21165561 |
|
NCBI chr 2:77,735,586...77,743,451
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G |
CALR |
calreticulin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15048980 |
|
NCBI chr 2:66,098,263...66,102,074
Ensembl chr 2:66,098,229...66,102,132
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G |
CALU |
calumenin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15048980 |
|
NCBI chr18:19,841,718...19,875,804
Ensembl chr18:19,841,719...19,875,786
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G |
CAT |
catalase |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:21749277 PMID:22580338 |
|
NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
CCL2 |
chemokine (C-C motif) ligand 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25199511 PMID:32512068 |
|
NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026
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G |
CCL3L1 |
chemokine (C-C motif) ligand 3-like 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:36346222 |
|
NCBI chr12:39,491,999...39,493,345
Ensembl chr12:39,491,914...39,493,774
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G |
CCL5 |
C-C motif chemokine ligand 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18985009 |
|
NCBI chr12:39,652,731...39,659,121
Ensembl chr12:39,648,598...39,659,118
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G |
CD82 |
CD82 molecule |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:20075392 |
|
NCBI chr 2:17,751,153...17,803,172
Ensembl chr 2:17,750,660...17,803,126
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G |
CDH1 |
cadherin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism|therapeutic |
CTD |
PMID:19839049 PMID:22580338 |
|
NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986
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G |
CDH2 |
cadherin 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27811057 |
|
NCBI chr 6:112,396,713...112,629,073
Ensembl chr 6:112,396,721...112,628,432
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G |
CDKN2A |
cyclin dependent kinase inhibitor 2A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24495407 |
|
NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854
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G |
CFL1 |
cofilin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15048980 |
|
NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035
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|
G |
CHI3L1 |
chitinase 3 like 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21029458 |
|
NCBI chr 9:113,885,541...113,895,033
Ensembl chr 9:113,885,542...113,895,131
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G |
CHRNA7 |
cholinergic receptor nicotinic alpha 7 subunit |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18844224 |
|
NCBI chr 1:142,803,697...142,937,124
Ensembl chr 1:142,803,701...142,937,123
|
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G |
CSE1L |
chromosome segregation 1 like |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34022224 |
|
NCBI chr17:50,744,896...50,796,835
Ensembl chr17:50,744,910...50,797,548
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|
G |
CSTB |
cystatin B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19747051 PMID:22287159 |
|
NCBI chr13:206,706,060...206,710,598
Ensembl chr13:206,706,063...206,710,646
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|
G |
CTBP2 |
C-terminal binding protein 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28414304 |
|
NCBI chr14:134,329,312...134,488,805
Ensembl chr14:134,329,941...134,487,755
|
|
G |
CTNNB1 |
catenin beta 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23707762 PMID:26990689 |
|
NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311
|
|
G |
CTSB |
cathepsin B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19700239 PMID:19747051 |
|
NCBI chr14:15,014,139...15,035,081
Ensembl chr14:15,011,711...15,033,877
|
|
G |
CTSD |
cathepsin D |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15048980 |
|
NCBI chr 2:1,188,548...1,197,642
Ensembl chr 2:1,188,549...1,197,643
|
|
G |
CTSS |
cathepsin S |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19700239 |
|
NCBI chr 4:98,415,273...98,442,952
Ensembl chr 4:98,417,883...98,442,950
|
|
G |
CTU2 |
cytosolic thiouridylase subunit 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27811057 |
|
NCBI chr 6:964,551...976,881
Ensembl chr 6:964,566...976,832
|
|
G |
CXCL12 |
C-X-C motif chemokine ligand 12 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19700239 PMID:25231984 PMID:25753200 |
|
NCBI chr14:91,516,383...91,543,857
Ensembl chr14:91,516,431...91,552,752
|
|
G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:32512068 |
|
NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
|
|
G |
CXCR4 |
C-X-C motif chemokine receptor 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25753200 |
|
NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,232
|
|
G |
CYP2E1 |
cytochrome P450 family 2 subfamily E member 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr14:141,690,737...141,703,078
Ensembl chr14:141,690,426...141,736,817
|
|
G |
DEK |
DEK proto-oncogene |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21291860 PMID:27811057 |
|
NCBI chr 7:13,901,562...13,935,477
Ensembl chr 7:13,872,775...13,935,173
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|
G |
DLX4 |
distal-less homeobox 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr12:26,155,520...26,161,310
Ensembl chr12:26,155,561...26,161,298
|
|
G |
DMD |
dystrophin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24793134 |
|
NCBI chr X:27,028,223...29,650,728
Ensembl chr X:27,028,231...28,383,840
|
|
G |
DNMT1 |
DNA methyltransferase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28544374 |
|
NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844
|
|
G |
EDNRB |
endothelin receptor type B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr11:50,073,300...50,102,879
Ensembl chr11:50,072,554...50,102,884
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|
G |
EEF2 |
eukaryotic translation elongation factor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21554491 |
|
NCBI chr 2:74,746,541...74,756,687
Ensembl chr 2:74,747,080...74,756,680
|
|
G |
EGF |
epidermal growth factor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15802018 PMID:22869556 PMID:23064031 PMID:24587105 PMID:27634460 |
|
NCBI chr 8:112,235,607...112,330,062
Ensembl chr 8:112,234,386...112,330,046
|
|
G |
EGFR |
epidermal growth factor receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18844224 PMID:23867902 |
|
NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589
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|
G |
EIF4E |
eukaryotic translation initiation factor 4E |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20388789 |
|
NCBI chr 8:121,409,633...121,464,467
Ensembl chr 8:121,409,731...121,464,471
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|
G |
ELP1 |
elongator acetyltransferase complex subunit 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27811057 |
|
NCBI chr 1:249,905,550...249,980,570
Ensembl chr 1:249,905,351...249,981,641
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|
G |
ELP3 |
elongator acetyltransferase complex subunit 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27811057 |
|
NCBI chr14:11,832,947...11,940,080
Ensembl chr14:11,832,962...11,940,070
|
|
G |
EN1 |
engrailed homeobox 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr15:24,402,605...24,408,377
Ensembl chr15:24,402,370...24,407,692
|
|
G |
ENO1 |
enolase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15654357 |
|
NCBI chr 6:69,385,879...69,401,664
Ensembl chr 6:69,385,879...69,401,151
|
|
G |
EPAS1 |
endothelial PAS domain protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26735578 PMID:30090327 |
|
NCBI chr 3:94,167,759...94,253,662
Ensembl chr 3:94,165,816...94,254,079
|
|
G |
EPO |
erythropoietin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16699298 |
|
NCBI chr 3:8,620,508...8,622,936
Ensembl chr 3:8,620,508...8,622,936
|
|
G |
EPOR |
erythropoietin receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16699298 |
|
NCBI chr 2:70,063,601...70,068,821
Ensembl chr 2:70,063,519...70,068,821
|
|
G |
EPS8 |
EGFR pathway substrate 8, signaling adaptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19799886 |
|
NCBI chr 5:56,817,445...57,005,117
Ensembl chr 5:56,817,606...57,005,113
|
|
G |
ESR1 |
estrogen receptor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism|therapeutic |
CTD |
PMID:26990689 PMID:27366082 PMID:35044086 |
|
NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363
|
|
G |
FAM83A |
family with sequence similarity 83 member A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34931434 |
|
NCBI chr 4:16,169,697...16,186,015
Ensembl chr 4:16,169,708...16,184,941
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|
G |
FGFR4 |
fibroblast growth factor receptor 4 |
|
ISO |
ClinVar Annotator: match by term: Cancer progression and tumor cell motility |
ClinVar |
PMID:11830541 PMID:25741868 PMID:26675719 PMID:33116287 |
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NCBI chr 2:80,841,536...80,853,791
Ensembl chr 2:80,841,536...80,853,796
|
|
G |
FN1 |
fibronectin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24014025 |
|
NCBI chr15:117,658,158...117,737,145
Ensembl chr15:117,658,099...117,731,014
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|
G |
FOXP1 |
forkhead box P1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25485836 |
|
NCBI chr13:52,346,844...52,974,358
Ensembl chr13:52,348,234...52,876,892
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|
G |
FTH1 |
ferritin heavy chain 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20390345 |
|
NCBI chr 2:9,535,051...9,537,979
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|
G |
FTL |
ferritin light chain |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20390345 |
|
NCBI chr 6:54,231,121...54,232,756
Ensembl chr 6:54,231,172...54,232,750
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|
G |
GAB2 |
GRB2 associated binding protein 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21996746 |
|
NCBI chr 9:12,663,658...12,851,423
Ensembl chr 9:12,663,657...12,851,342
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|
G |
HDAC3 |
histone deacetylase 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34973135 |
|
NCBI chr 2:143,273,188...143,287,421
Ensembl chr 2:143,273,192...143,287,399
|
|
G |
HGF |
hepatocyte growth factor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:9932610 PMID:15654357 |
|
NCBI chr 9:98,437,771...98,513,573
Ensembl chr 9:98,438,143...98,513,564
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|
G |
HIF1A |
hypoxia inducible factor 1 subunit alpha |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:12811834 PMID:29501572 |
|
NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845
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|
G |
HMGA2 |
high mobility group AT-hook 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28830677 |
|
NCBI chr 5:30,188,521...30,329,635
|
|
G |
HMGCS2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27816970 |
|
NCBI chr 4:101,420,941...101,440,302
Ensembl chr 4:101,420,872...101,438,126
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|
G |
HMOX1 |
heme oxygenase 1 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:24211270 |
|
|
|
G |
HOXB13 |
homeobox B13 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr12:24,948,307...24,950,661
Ensembl chr12:24,947,687...24,950,714
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G |
HOXB3 |
homeobox B3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34652879 |
|
NCBI chr12:24,803,119...24,827,557
Ensembl chr12:24,804,647...24,809,937
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|
G |
HPSE |
heparanase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22240343 |
|
NCBI chr 8:135,082,199...135,120,887
Ensembl chr 8:135,097,725...135,120,887
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|
G |
HRAS |
HRas proto-oncogene, GTPase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23877152 |
|
NCBI chr 2:299,662...302,539
Ensembl chr 2:299,660...302,501
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|
G |
ID4 |
inhibitor of DNA binding 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:14633621 |
|
NCBI chr 7:15,281,535...15,284,895
Ensembl chr 7:15,281,757...15,282,839
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|
G |
IGF1 |
insulin like growth factor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18398872 |
|
NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
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|
G |
IL1RN |
interleukin 1 receptor antagonist |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:27567548 |
|
|
|
G |
IL6 |
interleukin 6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26101800 PMID:26284488 |
|
NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
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|
G |
INS |
insulin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24587105 |
|
NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
|
|
G |
IREB2 |
iron responsive element binding protein 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20390345 |
|
NCBI chr 7:47,481,539...47,529,199
Ensembl chr 7:47,478,706...47,529,242
|
|
G |
ITGA5 |
integrin subunit alpha 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21224397 |
|
NCBI chr 5:19,587,361...19,610,580
Ensembl chr 5:19,586,746...19,610,362
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|
G |
ITGB1 |
integrin subunit beta 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21224397 |
|
NCBI chr10:56,078,393...56,130,608
Ensembl chr10:56,078,396...56,173,326
|
|
G |
ITPK1 |
inositol-tetrakisphosphate 1-kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr 7:114,361,976...114,520,805
Ensembl chr 7:114,361,968...114,520,793
|
|
G |
KCND2 |
potassium voltage-gated channel subfamily D member 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34418280 |
|
NCBI chr18:26,139,457...26,624,210
Ensembl chr18:26,139,457...26,623,233
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|
G |
KDM1A |
lysine demethylase 1A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22493729 |
|
NCBI chr 6:80,903,407...80,971,875
Ensembl chr 6:80,903,424...80,971,873
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|
G |
KRT19 |
keratin 19 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15048980 |
|
NCBI chr12:21,115,453...21,119,115
Ensembl chr12:21,115,448...21,119,107
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|
G |
KRT7 |
keratin 7 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19921857 |
|
NCBI chr 5:17,553,192...17,570,582
Ensembl chr 5:17,555,728...17,570,581
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|
G |
LDHB |
lactate dehydrogenase B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15048980 |
|
NCBI chr 5:51,810,932...51,831,218
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|
G |
LEF1 |
lymphoid enhancer binding factor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27811057 |
|
NCBI chr 8:113,824,511...113,944,078
Ensembl chr 8:113,825,161...113,944,070
|
|
G |
LIN28A |
lin-28 homolog A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26910839 |
|
NCBI chr 6:83,806,178...83,818,550
Ensembl chr 6:83,806,056...83,818,633
|
|
G |
LOC100513450 |
P antigen family member 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr X:43,489,559...43,496,654
Ensembl chr X:43,446,109...43,494,094
|
|
G |
LOC100516084 |
cytoplasmic tRNA 2-thiolation protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27811057 |
|
NCBI chr 6:58,388,646...58,396,509
|
|
G |
LOC110258578 |
interleukin-1 beta-like |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27567548 |
|
|
|
G |
LOXL2 |
lysyl oxidase like 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24014025 |
|
NCBI chr14:7,435,861...7,540,699
Ensembl chr14:7,435,867...7,540,704
|
|
G |
MAPK1 |
mitogen-activated protein kinase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22580338 |
|
NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513
|
|
G |
MAPK3 |
mitogen-activated protein kinase 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22580338 |
|
NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
|
|
G |
MET |
MET proto-oncogene, receptor tyrosine kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15654357 |
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NCBI chr18:29,426,044...29,541,526
Ensembl chr18:29,426,048...29,541,512
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G |
MIR155 |
microRNA mir-155 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28315615 |
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NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902
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G |
MIR186 |
microRNA mir-186 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34291859 |
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NCBI chr 6:141,943,328...141,943,409
Ensembl chr 6:141,943,328...141,943,409
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G |
MIR191 |
microRNA mir-191 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29277653 |
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NCBI chr13:31,655,484...31,655,563
Ensembl chr13:31,655,484...31,655,563
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G |
MIR21 |
microRNA mir-21 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26101800 PMID:29501572 |
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NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358
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G |
MIR217-1 |
microRNA mir-217-1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25538231 |
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NCBI chr 3:85,341,255...85,341,361
Ensembl chr 3:85,341,255...85,341,361
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G |
MIR497 |
microRNA mir-497 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:35066776 |
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NCBI chr12:52,422,329...52,422,408
Ensembl chr12:52,422,330...52,422,411
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G |
MIR532 |
microRNA mir-532 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30639441 |
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NCBI chr X:43,705,258...43,705,337
Ensembl chr X:43,705,258...43,705,337
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G |
MIR708 |
microRNA mir-708 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:34652879 |
|
NCBI chr 9:13,780,171...13,780,250
Ensembl chr 9:13,780,171...13,780,250
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G |
MIR874 |
microRNA mir-874 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:30004169 |
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NCBI chr 2:139,660,118...139,660,201
Ensembl chr 2:139,660,118...139,660,201
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G |
MMP1 |
matrix metallopeptidase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22580338 |
|
NCBI chr 9:33,411,738...33,420,205
Ensembl chr 9:33,411,065...33,420,076
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G |
MMP14 |
matrix metallopeptidase 14 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24014025 |
|
NCBI chr 7:76,174,502...76,185,931
Ensembl chr 7:76,172,971...76,185,928
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G |
MMP2 |
matrix metallopeptidase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18398872 PMID:19770485 PMID:22321834 PMID:23707804 PMID:34278709 |
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NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982
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G |
MMP3 |
matrix metallopeptidase 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20188714 PMID:26284488 |
|
NCBI chr 9:33,446,969...33,453,995
Ensembl chr 9:33,446,836...33,454,000
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G |
MMP9 |
matrix metallopeptidase 9 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19617202 PMID:19700239 PMID:20188714 PMID:21187089 PMID:22503731 PMID:23867902 PMID:24333868 More...
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NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788
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G |
MT-2B |
metallothionein-2A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21187089 |
|
NCBI chr 6:18,645,125...18,646,034
Ensembl chr 6:18,645,153...18,646,033
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G |
MT3 |
metallothionein 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23794209 |
|
NCBI chr 6:18,634,735...18,636,134
Ensembl chr 6:18,634,261...18,636,131
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G |
MTDH |
metadherin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29315995 |
|
NCBI chr 4:39,052,895...39,113,380
Ensembl chr 4:39,051,537...39,113,385
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G |
MYD88 |
MYD88 innate immune signal transduction adaptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21473897 |
|
NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109
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G |
MYH9 |
myosin heavy chain 9 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28650484 |
|
NCBI chr 5:11,365,603...11,456,475
Ensembl chr 5:11,360,660...11,456,472
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G |
MYLK |
myosin light chain kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:10232591 PMID:12970723 |
|
NCBI chr13:136,509,878...136,809,674
Ensembl chr13:136,509,755...136,809,668
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G |
NCAM1 |
neural cell adhesion molecule 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19700239 |
|
NCBI chr 9:40,628,602...40,960,605
Ensembl chr 9:40,628,631...40,960,591
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G |
NEK2 |
NIMA related kinase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28509438 |
|
NCBI chr 9:131,547,044...131,560,527
Ensembl chr 9:131,547,069...131,561,095
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:32682831 |
|
NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183
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G |
NME1 |
NME/NM23 nucleoside diphosphate kinase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15048980 |
|
NCBI chr12:27,416,308...27,435,044
Ensembl chr12:27,416,346...27,436,140
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G |
NOTCH2 |
notch receptor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30670679 |
|
NCBI chr 4:100,951,522...101,152,348
Ensembl chr 4:100,981,636...101,150,195
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G |
NRG1 |
neuregulin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19617202 |
|
NCBI chr15:52,625,550...53,688,003
Ensembl chr15:52,630,679...52,839,505
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G |
NUAK1 |
NUAK family kinase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 PMID:26873845 |
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NCBI chr 5:14,089,584...14,177,584
Ensembl chr 5:14,102,006...14,177,584
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G |
PAK1 |
p21 (RAC1) activated kinase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:35066776 |
|
NCBI chr 9:11,830,095...11,973,074
Ensembl chr 9:11,830,095...12,020,415
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G |
PAX6 |
paired box 6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr 2:28,971,565...29,001,149
Ensembl chr 2:28,978,287...29,001,200
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G |
PDCD4 |
programmed cell death 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23272133 |
|
NCBI chr14:121,271,824...121,334,767
Ensembl chr14:121,305,629...121,338,740
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|
G |
PIP5K1A |
phosphatidylinositol-4-phosphate 5-kinase type 1 alpha |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34755307 |
|
NCBI chr 4:98,012,941...98,062,166
Ensembl chr 4:98,012,945...98,056,815
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|
G |
PKM |
pyruvate kinase M1/2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15048980 PMID:15654357 |
|
NCBI chr 7:60,971,807...61,032,780
Ensembl chr 7:60,975,667...61,004,316 Ensembl chr 7:60,975,667...61,004,316
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G |
PLAU |
plasminogen activator, urokinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:14644129 PMID:26284488 |
|
NCBI chr14:76,629,313...76,635,173
Ensembl chr14:76,629,299...76,635,172
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|
G |
PLAUR |
plasminogen activator, urokinase receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:12198772 PMID:22261521 |
RGD:729319 |
NCBI chr 6:50,489,773...50,505,453
Ensembl chr 6:50,489,777...50,505,418
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|
G |
PPP1R12B |
protein phosphatase 1 regulatory subunit 12B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28650484 |
|
NCBI chr10:24,463,900...24,637,361
Ensembl chr10:24,465,041...24,637,358
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|
G |
PRDX2 |
peroxiredoxin 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23911960 |
|
NCBI chr 2:66,207,829...66,211,474
Ensembl chr 2:66,207,828...66,212,009
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|
G |
PTEN |
phosphatase and tensin homolog |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:21994956 |
|
NCBI chr14:99,929,590...100,021,619
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|
G |
PTK2 |
protein tyrosine kinase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism|therapeutic |
CTD |
PMID:12811834 PMID:25199511 |
|
NCBI chr 4:2,656,606...2,896,060
Ensembl chr 4:2,656,614...2,896,054
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G |
RAB27A |
RAB27A, member RAS oncogene family |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34291859 |
|
NCBI chr 1:116,532,816...116,606,477
Ensembl chr 1:116,532,974...116,606,474
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G |
RAB27B |
RAB27B, member RAS oncogene family |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34291859 |
|
NCBI chr 1:104,241,500...104,418,721
Ensembl chr 1:104,241,571...104,417,084
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|
G |
RASAL2 |
RAS protein activator like 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34826200 |
|
NCBI chr 9:119,941,303...120,329,817
Ensembl chr 9:119,941,862...120,325,316
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|
G |
RBM38 |
RNA binding motif protein 38 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:34453780 |
|
NCBI chr17:57,783,156...57,802,495
Ensembl chr17:57,783,154...57,797,990
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G |
RECK |
reversion inducing cysteine rich protein with kazal motifs |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:20127710 |
|
NCBI chr 1:236,821,243...236,898,280
Ensembl chr 1:236,821,414...236,898,276
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|
G |
RELA |
RELA proto-oncogene, NF-kB subunit |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19896475 PMID:29501572 |
|
NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469
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G |
RHOA |
ras homolog family member A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19896475 |
|
NCBI chr13:31,918,484...31,991,207
Ensembl chr13:31,918,834...31,986,607
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G |
RNF207 |
ring finger protein 207 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr 6:67,105,347...67,119,167
Ensembl chr 6:67,106,552...67,116,510
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|
G |
RPL3L |
ribosomal protein L3 like |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr 3:40,004,907...40,016,702
Ensembl chr 3:40,007,868...40,016,699
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G |
RPS6KA3 |
ribosomal protein S6 kinase A3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21488662 |
|
NCBI chr X:16,452,401...16,576,854
Ensembl chr X:16,452,405...16,576,859
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G |
RPSA |
ribosomal protein SA |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15048980 |
|
NCBI chr13:24,072,551...24,081,536
Ensembl chr13:24,072,527...24,081,541
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G |
S100A11 |
S100 calcium binding protein A11 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20388789 |
|
NCBI chr 4:97,233,833...97,239,081
Ensembl chr 4:97,233,811...97,243,423
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G |
S100A4 |
S100 calcium binding protein A4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15048980 |
|
NCBI chr 4:96,088,102...96,091,160
Ensembl chr 4:96,088,201...96,091,156
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G |
S1PR2 |
sphingosine-1-phosphate receptor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26518876 |
|
NCBI chr 2:69,050,396...69,057,270
Ensembl chr 2:69,049,270...69,057,270
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G |
SEPTIN9 |
septin 9 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20388789 |
|
NCBI chr12:4,254,771...4,347,526
Ensembl chr12:4,254,775...4,405,628
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G |
SET |
SET nuclear proto-oncogene |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24555657 |
|
NCBI chr 1:269,050,447...269,064,462
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G |
SLC39A10 |
solute carrier family 39 member 10 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17359283 |
|
NCBI chr15:99,584,830...99,724,621
Ensembl chr15:99,584,872...99,724,611
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G |
SLC6A12 |
solute carrier family 6 member 12 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr 5:67,550,285...67,573,858
Ensembl chr 5:67,550,289...67,572,588
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G |
SMPD1 |
sphingomyelin phosphodiesterase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24951586 |
|
NCBI chr 9:3,324,091...3,328,493
Ensembl chr 9:3,324,442...3,328,457
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G |
SNAI1 |
snail family transcriptional repressor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22580338 PMID:24014025 |
|
NCBI chr17:51,546,446...51,552,498
Ensembl chr17:51,546,477...51,552,499
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G |
SNAI2 |
snail family transcriptional repressor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22580338 |
|
NCBI chr 4:79,264,880...79,268,475
Ensembl chr 4:79,264,880...79,268,475
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G |
SOD2 |
superoxide dismutase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:10853026 PMID:11053990 PMID:15048980 PMID:15654357 PMID:21749277 PMID:22580338 More...
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NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
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G |
SORL1 |
sortilin related receptor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr 9:48,435,350...48,653,670
Ensembl chr 9:48,435,345...48,653,655
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G |
SOX11 |
SRY-box transcription factor 11 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr 3:129,797,438...129,800,568
Ensembl chr 3:129,798,854...129,800,197
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G |
SOX9 |
SRY-box transcription factor 9 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:32682831 |
|
NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315
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G |
SP1 |
Sp1 transcription factor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26317792 PMID:35072892 |
|
NCBI chr 5:18,588,763...18,633,177
Ensembl chr 5:18,588,758...18,630,089
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G |
SRC |
SRC proto-oncogene, non-receptor tyrosine kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18844224 PMID:21291860 |
|
NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860
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G |
STAT3 |
signal transducer and activator of transcription 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26101800 |
|
NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992
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G |
SUMO1 |
small ubiquitin like modifier 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15048980 |
|
NCBI chr15:105,820,237...105,850,099
Ensembl chr15:105,818,858...105,850,233
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G |
TBX15 |
T-box transcription factor 15 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr 4:101,918,891...102,032,280
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G |
TF |
transferrin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20390345 |
|
NCBI chr13:74,930,655...74,970,599
Ensembl chr13:74,930,655...74,972,763
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G |
TFPI2 |
tissue factor pathway inhibitor 2 |
|
ISO |
|
RGD |
PMID:11687973 |
RGD:11060269 |
NCBI chr 9:73,684,236...73,694,663
Ensembl chr 9:73,673,535...73,689,095
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G |
TGFB1 |
transforming growth factor beta 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23992306 PMID:24727557 PMID:24793912 PMID:25884904 PMID:26896736 PMID:32745479 More...
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NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046
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G |
TGIF1 |
TGFB induced factor homeobox 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25791921 |
|
NCBI chr 6:103,226,395...103,234,591
Ensembl chr 6:103,226,402...103,234,610
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G |
TIMP1 |
TIMP metallopeptidase inhibitor 1 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:1318976 |
|
NCBI chr X:42,103,251...42,106,289
Ensembl chr X:42,102,172...42,106,296
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G |
TIMP3 |
TIMP metallopeptidase inhibitor 3 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:23109338 |
|
NCBI chr 5:12,185,816...12,242,599
Ensembl chr 5:12,185,818...12,242,581
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G |
TKT |
transketolase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15654357 |
|
NCBI chr13:35,348,921...35,377,518
Ensembl chr13:35,348,915...35,377,587
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G |
TLN1 |
talin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21291860 |
|
NCBI chr 1:236,416,041...236,450,978
Ensembl chr 1:236,416,044...236,450,922
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G |
TLR4 |
toll like receptor 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21473897 |
|
NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970
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G |
TMEM139 |
transmembrane protein 139 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr18:6,970,887...6,974,130
Ensembl chr18:6,970,891...6,973,394
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G |
TNF |
tumor necrosis factor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22199285 PMID:23431386 PMID:23899529 PMID:24613819 |
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NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416
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|
G |
TP53BP2 |
tumor protein p53 binding protein 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28650484 |
|
NCBI chr10:19,823,932...19,889,883
Ensembl chr10:19,823,936...19,889,869
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G |
TRIM47 |
tripartite motif containing 47 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:31981573 |
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NCBI chr12:5,535,259...5,539,721
Ensembl chr12:5,535,236...5,539,715
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G |
TRPM7 |
transient receptor potential cation channel subfamily M member 7 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30710498 |
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NCBI chr 1:121,146,093...121,250,227
Ensembl chr 1:121,146,117...121,250,224
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G |
TWIST1 |
twist family bHLH transcription factor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22155737 |
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NCBI chr 9:88,286,911...88,290,131
Ensembl chr 9:88,289,407...88,290,015
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G |
TXN |
thioredoxin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15048980 |
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NCBI chr 1:251,264,180...251,278,000
Ensembl chr 1:251,263,175...251,277,988
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G |
UBQLN1 |
ubiquilin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24747970 |
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NCBI chr10:31,275,916...31,317,521
Ensembl chr10:31,275,868...31,317,516
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G |
VIM |
vimentin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27811057 |
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NCBI chr10:43,516,441...43,526,172
Ensembl chr10:43,517,307...43,526,170
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G |
XPC |
XPC complex subunit, DNA damage recognition and repair factor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27777383 |
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NCBI chr13:70,348,841...70,397,194
Ensembl chr13:70,348,864...70,397,772
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G |
XRCC3 |
X-ray repair cross complementing 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21283680 |
|
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G |
YAP1 |
Yes1 associated transcriptional regulator |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34351699 |
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NCBI chr 9:32,811,629...32,924,926
Ensembl chr 9:32,811,416...32,925,603
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G |
ZBTB16 |
zinc finger and BTB domain containing 16 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26213588 |
|
NCBI chr 9:41,639,536...41,839,254
Ensembl chr 9:41,639,701...41,836,742
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G |
ZEB1 |
zinc finger E-box binding homeobox 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21954225 |
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NCBI chr10:42,013,114...42,216,139
Ensembl chr10:42,013,084...42,214,205
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G |
ZEB2 |
zinc finger E-box binding homeobox 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21954225 |
|
NCBI chr15:7,498,879...7,631,347
Ensembl chr15:7,499,026...7,632,655
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G |
ZFP36 |
ZFP36 ring finger protein |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:25556371 |
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NCBI chr 6:48,063,732...48,066,235
Ensembl chr 6:48,063,677...48,066,250
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G |
ZFR |
zinc finger RNA binding protein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34323000 |
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NCBI chr16:18,561,909...18,656,341
Ensembl chr16:18,560,280...18,656,294
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G |
ZNF367 |
zinc finger protein 367 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:34351699 |
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NCBI chr10:25,707,711...25,735,073
Ensembl chr10:25,707,722...25,735,067
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G |
ABCB1 |
ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:12015757 |
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NCBI chr 9:93,049,955...93,146,469
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G |
ABCC4 |
ATP binding cassette subfamily C member 4 (PEL blood group) |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17003774 |
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NCBI chr11:64,089,149...64,309,831
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G |
ACE |
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18059164 |
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NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,703
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G |
ACKR3 |
atypical chemokine receptor 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22180778 |
|
NCBI chr15:136,370,457...136,382,559
Ensembl chr15:136,370,530...136,382,553
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G |
ACSBG1 |
acyl-CoA synthetase bubblegum family member 1 |
|
ISO |
associated with pheochromocytoma |
RGD |
PMID:29067245 |
RGD:13831131 |
NCBI chr 7:47,705,091...47,760,797
Ensembl chr 7:47,705,121...47,762,538
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G |
ACVR2A |
activin A receptor type 2A |
exacerbates |
ISO |
associated with colon cancer;mRNA,protein:decreased expression:colon (human) |
RGD |
PMID:30310521 |
RGD:151361136 |
NCBI chr15:4,177,333...4,259,056
Ensembl chr15:4,173,805...4,259,706
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G |
ADGRB1 |
adhesion G protein-coupled receptor B1 |
|
ISO |
associated with colorectal cancer |
RGD |
PMID:9772287 |
RGD:13831353 |
NCBI chr 4:1,582,321...1,658,639
Ensembl chr 4:1,582,330...1,647,573
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G |
ADORA2B |
adenosine A2b receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27590504 |
|
NCBI chr12:59,431,834...59,449,701
Ensembl chr12:59,431,513...59,449,672
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G |
AGTR1 |
angiotensin II receptor type 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18059164 |
|
NCBI chr13:88,934,873...88,980,317
Ensembl chr13:88,934,868...88,983,105
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G |
AGTR2 |
angiotensin II receptor type 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18059164 |
|
NCBI chr X:95,267,709...95,272,237
Ensembl chr X:95,269,300...95,270,388
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G |
AHR |
aryl hydrocarbon receptor |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:21948867 |
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NCBI chr 9:86,511,866...86,555,950
Ensembl chr 9:86,511,369...86,555,943
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G |
AKIRIN2 |
akirin 2 |
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ISO |
|
RGD |
PMID:18460465 |
RGD:2306009 |
NCBI chr 1:56,047,188...56,075,342
Ensembl chr 1:56,046,327...56,070,163
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G |
AKT2 |
AKT serine/threonine kinase 2 |
|
ISO |
associated with Mammary Neoplasms, Experimental |
RGD |
PMID:19491266 |
RGD:2315599 |
NCBI chr 6:48,555,785...48,620,472
Ensembl chr 6:48,555,795...48,587,919
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G |
ALDOA |
aldolase, fructose-bisphosphate A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20562527 |
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NCBI chr 3:18,246,036...18,260,167
Ensembl chr 3:18,253,384...18,260,163
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G |
ALK |
ALK receptor tyrosine kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22986231 PMID:22999080 |
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NCBI chr 3:109,411,146...110,105,755
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G |
ALOX5 |
arachidonate 5-lipoxygenase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20061081 |
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NCBI chr14:90,859,209...90,907,084
Ensembl chr14:90,859,016...90,907,094
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G |
AMIGO2 |
adhesion molecule with Ig like domain 2 |
|
ISO |
Liver Metastasis |
RGD |
PMID:28272394 |
RGD:14394499 |
NCBI chr 5:77,642,144...77,645,748
Ensembl chr 5:77,642,195...77,645,753
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G |
ANGPTL4 |
angiopoietin like 4 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:17130448 |
|
NCBI chr 2:70,905,767...70,912,892
Ensembl chr 2:70,904,531...70,912,974
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G |
ANTXR1 |
ANTXR cell adhesion molecule 1 |
|
ISO |
associated with Mammary Neoplasms, Experimental; |
RGD |
PMID:22085271 |
RGD:9684855 |
NCBI chr 3:73,157,744...73,398,379
Ensembl chr 3:73,157,747...73,398,379
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G |
ANXA1 |
annexin A1 |
treatment |
ISO |
associated with Mammary Neoplasms, Experimental associated with Mammary Neoplasms, Experimental;protein:increased expression:lung CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:9514092 PMID:20308542 PMID:20821804 |
RGD:2306939 RGD:7421541 RGD:7421563 |
NCBI chr 1:226,414,200...226,431,963
Ensembl chr 1:226,414,306...226,432,279
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G |
ANXA4 |
annexin A4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17085005 |
|
NCBI chr 3:72,623,311...72,654,591
Ensembl chr 3:72,622,358...72,694,212
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G |
ANXA7 |
annexin A7 |
|
ISO |
associated with Breast Neoplasms;protein:increased expression:breast associated with Prostatic Neoplasms;protein:decreased expression:prostate gland |
RGD |
PMID:11287641 PMID:15073110 |
RGD:2292655 RGD:2292656 |
NCBI chr14:76,205,238...76,234,646
Ensembl chr14:76,205,232...76,234,631
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G |
APOE |
apolipoprotein E |
|
ISO |
|
RGD |
PMID:22469977 |
RGD:7771597 |
NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330
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G |
ARHGDIA |
Rho GDP dissociation inhibitor alpha |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20562527 |
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NCBI chr12:1,113,358...1,117,319
Ensembl chr12:1,113,379...1,119,315
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G |
ARID1A |
AT-rich interaction domain 1A |
disease_progression |
ISO |
in lung; associated with hepatocellular carcinoma |
RGD |
PMID:25975202 |
RGD:125097495 |
NCBI chr 6:84,049,729...84,124,302
Ensembl chr 6:84,049,087...84,123,349
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G |
ATP6V1C1 |
ATPase H+ transporting V1 subunit C1 |
|
ISO |
associated with Mammary Neoplasms, Experimental |
RGD |
PMID:24155661 |
RGD:14700647 |
NCBI chr 4:34,033,943...34,084,990
Ensembl chr 4:34,029,295...34,222,405
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G |
AXL |
AXL receptor tyrosine kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26206560 |
|
NCBI chr 6:49,245,802...49,277,917
Ensembl chr 6:49,245,673...49,277,914
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G |
AZIN1 |
antizyme inhibitor 1 |
|
ISO |
associated with stomach cancer;RNA:increased editing:stomach associated with colorectal cancer;RNA:increased editing:colorectum |
RGD |
PMID:29925690 PMID:30563560 |
RGD:14700703 RGD:14700704 |
NCBI chr 4:34,221,368...34,257,261
Ensembl chr 4:34,234,679...34,257,134
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G |
BAX |
BCL2 associated X, apoptosis regulator |
|
ISO |
associated with Carcinoma, Infiltrating Duct |
RGD |
PMID:17288732 |
RGD:1643356 |
NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
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G |
BCL2 |
BCL2 apoptosis regulator |
|
ISO |
associated with Carcinoma, Renal Cell associated with Breast Neoplasms |
RGD |
PMID:12810203 PMID:16826579 |
RGD:2293020 RGD:2293021 |
NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
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G |
BMP6 |
bone morphogenetic protein 6 |
severity |
ISO |
associated with Prostatic Neoplasms;protein:increased expression:bone |
RGD |
PMID:16166304 |
RGD:2289018 |
NCBI chr 7:5,058,817...5,208,868
Ensembl chr 7:5,058,817...5,210,270
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|
G |
BMP7 |
bone morphogenetic protein 7 |
disease_progression |
ISO |
associated with Prostatic Neoplasms;mRNA:increased expression:bone associated with Breast Neoplasms;protein:increased expression:breast |
RGD |
PMID:12539225 PMID:17895257 |
RGD:2289029 RGD:2289033 |
NCBI chr17:57,567,770...57,676,516
Ensembl chr17:57,584,956...57,675,986
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|
G |
BRAF |
B-Raf proto-oncogene, serine/threonine kinase |
onset |
ISO |
associated with Melanoma; DNA:mutations: : |
RGD |
PMID:25623140 |
RGD:11567259 |
NCBI chr18:8,957,963...9,132,558
Ensembl chr18:8,957,991...9,132,553
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G |
BRD4 |
bromodomain containing 4 |
|
ISO |
|
RGD |
PMID:23950209 |
RGD:9586346 |
NCBI chr 2:62,250,958...62,345,851
Ensembl chr 2:62,250,989...62,345,362
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G |
BRMS1 |
BRMS1 transcriptional repressor and anoikis regulator |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:27501413 |
|
NCBI chr 2:6,046,077...6,053,672
Ensembl chr 2:6,046,098...6,053,667
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G |
BSG |
basigin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21956400 |
|
NCBI chr 2:77,735,586...77,743,451
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G |
CAB39 |
calcium binding protein 39 |
|
ISO |
associated with hepatocellular carcinoma; |
RGD |
PMID:28605041 |
RGD:14398832 |
NCBI chr15:131,492,575...131,584,963
Ensembl chr15:131,492,578...131,584,962
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G |
CACYBP |
calcyclin binding protein |
|
ISO |
associated with pancreatic neoplasms |
RGD |
PMID:18765951 |
RGD:2326146 |
NCBI chr 9:117,062,303...117,077,442
Ensembl chr 9:117,064,187...117,123,126
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G |
CAP1 |
cyclase associated actin cytoskeleton regulatory protein 1 |
|
ISO |
associated with Pancreatic Neoplasms; mRNA, protein:increased expression:pancreas |
RGD |
PMID:19188911 |
RGD:2326238 |
NCBI chr 6:95,811,485...95,840,576
Ensembl chr 6:95,812,179...95,840,570
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G |
CASP3 |
caspase 3 |
|
ISO |
associated with Breast Neoplasms |
RGD |
PMID:18064531 |
RGD:2293306 |
NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213
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G |
CAT |
catalase |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:12538496 PMID:22580338 PMID:23518002 |
|
NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
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G |
CAV1 |
caveolin 1 |
treatment |
ISO |
associated with Mammary Neoplasms, Experimental CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:15334058 PMID:15355971 PMID:20562527 |
RGD:2289106 RGD:8661780 |
NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465
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G |
CBX4 |
chromobox 4 |
|
ISO |
associated with Carcinoma, Hepatocellular; |
RGD |
PMID:24838576 |
RGD:9586738 |
NCBI chr12:2,520,913...2,527,245
Ensembl chr12:2,521,027...2,527,241
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G |
CBX5 |
chromobox 5 |
|
ISO |
associated with Lung Neoplasms; |
RGD |
PMID:22900142 |
RGD:9586743 |
NCBI chr 5:19,446,083...19,484,527
Ensembl chr 5:19,446,086...19,484,463
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G |
CCL2 |
chemokine (C-C motif) ligand 2 |
|
ISO |
associated with Mammary Neoplasms, Experimental |
RGD |
PMID:19629725 |
RGD:4891450 |
NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026
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G |
CCL20 |
C-C motif chemokine ligand 20 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30603057 |
|
NCBI chr15:129,172,743...129,176,069
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G |
CCL3L1 |
chemokine (C-C motif) ligand 3-like 1 |
|
ISO |
|
RGD |
PMID:18941229 |
RGD:7241810 |
NCBI chr12:39,491,999...39,493,345
Ensembl chr12:39,491,914...39,493,774
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|
G |
CCL5 |
C-C motif chemokine ligand 5 |
treatment |
ISO |
associated with Animal Mammary Neoplasms; |
RGD |
PMID:15692764 |
RGD:14995455 |
NCBI chr12:39,652,731...39,659,121
Ensembl chr12:39,648,598...39,659,118
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G |
CCN4 |
cellular communication network factor 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:30723155 |
|
NCBI chr 4:8,078,163...8,110,906
Ensembl chr 4:8,079,755...8,110,700
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G |
CCNA2 |
cyclin A2 |
|
ISO |
associated with Seminoma;protein:increased expression:testis |
RGD |
PMID:14696091 |
RGD:2293346 |
NCBI chr 8:102,260,346...102,266,274
Ensembl chr 8:102,260,215...102,266,309
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G |
CCND1 |
cyclin D1 |
treatment |
ISO |
associated with Carcinoma, Non-Small-Cell Lung;mRNA:splice variant associated with stomach cancer; human cells in mouse model |
RGD |
PMID:18715616 PMID:27431311 |
RGD:13434926 RGD:152995400 |
NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296
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|
G |
CCND2 |
cyclin D2 |
|
ISO |
associated with Breast Neoplasms;DNA:hypermethylated:brain |
RGD |
PMID:15131050 |
RGD:2289155 |
NCBI chr 5:66,092,483...66,114,575
Ensembl chr 5:66,087,379...66,114,571
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|
G |
CCNE1 |
cyclin E1 |
disease_progression |
ISO |
protein:altered processing associated with non-small cell lung carcinoma |
RGD |
PMID:11212263 PMID:17671189 |
RGD:13673913 RGD:2289229 |
NCBI chr 6:39,919,541...39,933,224
Ensembl chr 6:39,919,624...39,933,363
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|
G |
CCR5 |
C-C motif chemokine receptor 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:35072892 |
|
NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,895
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|
G |
CD274 |
CD274 molecule |
disease_progression |
ISO |
associated with ovarian cancer |
RGD |
PMID:23340297 |
RGD:41410797 |
NCBI chr 1:216,646,378...216,792,731
Ensembl chr 1:216,660,041...216,792,724
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|
G |
CD44 |
CD44 molecule |
|
ISO |
associated with Carcinoma, Renal Cell;protein:increased expression:kidney CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:18026989 PMID:23098472 |
RGD:2289347 |
NCBI chr 2:25,788,699...25,884,209
Ensembl chr 2:25,788,703...25,884,153
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G |
CD82 |
CD82 molecule |
|
ISO |
CTD Direct Evidence: therapeutic associated with Carcinoma, Infiltrating Duct;mRNA:decreased expression:brain associated with Prostatic Neoplasms;DNA:loss of heterozygosity associated with Prostatic Neoplasms;mRNA:decreased expression associated with Prostatic Neoplasms;mRNA:decreased expression:bone associated with Carcinoma, Hepatocellular;mRNA:decreased expression |
CTD RGD |
PMID:9254900 PMID:9831222 PMID:11275982 PMID:12806379 PMID:15592684 PMID:20075392 More...
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RGD:2289400 RGD:2289402 RGD:2289407 RGD:2289425 RGD:68869 |
NCBI chr 2:17,751,153...17,803,172
Ensembl chr 2:17,750,660...17,803,126
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|
G |
CD86 |
CD86 molecule |
|
ISO |
mRNA:decreased expression:mediastinal lymph node (rat) |
RGD |
PMID:18360875 |
RGD:4892237 |
NCBI chr13:138,427,573...138,504,307
Ensembl chr13:138,427,533...138,504,310
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G |
CDH1 |
cadherin 1 |
treatment |
ISO |
associated with Prostatic Neoplasms associated with stomach cancer; human cells in mouse model CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:17520682 PMID:18008331 PMID:22580338 PMID:27431311 |
RGD:152995400 RGD:2289488 |
NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986
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|
G |
CDH2 |
cadherin 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23876460 |
|
NCBI chr 6:112,396,713...112,629,073
Ensembl chr 6:112,396,721...112,628,432
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|
G |
CDKL2 |
cyclin dependent kinase like 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25333262 |
|
NCBI chr 8:71,231,148...71,260,902
Ensembl chr 8:71,231,152...71,260,815
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CDKN1A |
cyclin dependent kinase inhibitor 1A |
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ISO |
associated with Melanoma; |
RGD |
PMID:9194578 |
RGD:8662817 |
NCBI chr 7:32,354,776...32,363,771
Ensembl chr 7:32,359,455...32,363,761
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G |
CDKN2A |
cyclin dependent kinase inhibitor 2A |
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ISO |
associated with Paraganglioma, Extra-Adrenal;DNA:hypermethylation |
RGD |
PMID:18509008 |
RGD:8552280 |
NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854
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G |
CFL1 |
cofilin 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20562527 |
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NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035
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G |
CGA |
glycoprotein hormones, alpha polypeptide |
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ISO |
associated with Breast Neoplasms;protein:increased expression:serum |
RGD |
PMID:6768680 |
RGD:2293637 |
NCBI chr 1:55,552,675...55,569,057
Ensembl chr 1:55,551,320...55,568,991
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G |
CHEK1 |
checkpoint kinase 1 |
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ISO |
associated with Pancreatic Neoplasms |
RGD |
PMID:15448002 |
RGD:2317235 |
NCBI chr 9:52,759,224...52,790,878
Ensembl chr 9:52,753,528...52,790,700
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G |
CHUK |
component of inhibitor of nuclear factor kappa B kinase complex |
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ISO |
associated with prostate adenocarcinoma |
RGD |
PMID:17377533 |
RGD:2298657 |
NCBI chr14:111,316,178...111,351,669
Ensembl chr14:111,315,141...111,351,868
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G |
CIC |
capicua transcriptional repressor |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27869830 |
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NCBI chr 6:49,638,986...49,664,146
Ensembl chr 6:49,638,990...49,662,947
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G |
CLDN7 |
claudin 7 |
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ISO |
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RGD |
PMID:23390083 |
RGD:9685143 |
NCBI chr12:52,612,517...52,628,376
Ensembl chr12:52,612,510...52,628,362
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G |
CLIC1 |
chloride intracellular channel 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20562527 |
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NCBI chr 7:23,842,829...23,851,162
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G |
CLU |
clusterin |
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ISO |
associated with Breast Neoplasms |
RGD |
PMID:20307318 |
RGD:8883512 |
NCBI chr14:11,336,585...11,352,569
Ensembl chr14:11,336,595...11,349,764
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G |
CREB1 |
cAMP responsive element binding protein 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:29179997 |
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NCBI chr15:110,705,548...110,773,037
Ensembl chr15:110,705,496...110,771,728
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G |
CSF1 |
colony stimulating factor 1 |
|
ISO |
associated with Prostatic Neoplasms |
RGD |
PMID:18510570 |
RGD:2293638 |
NCBI chr 4:110,178,466...110,198,232
Ensembl chr 4:110,178,475...110,197,900
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G |
CSF1R |
colony stimulating factor 1 receptor |
exacerbates |
ISO |
associated with Prostatic Neoplasms associated with breast cancer CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:1390197 PMID:18510570 PMID:25005824 |
RGD:150524287 RGD:2293638 |
NCBI chr 2:151,102,138...151,130,311
Ensembl chr 2:151,102,147...151,147,633
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G |
CSF3 |
colony stimulating factor 3 |
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ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:7543699 PMID:9018096 |
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NCBI chr12:22,333,445...22,335,949
Ensembl chr12:22,333,449...22,338,753
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G |
CST3 |
cystatin C |
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ISO |
protein:decreased expression:cerebrospinal fluid |
RGD |
PMID:12589965 |
RGD:5686394 |
NCBI chr17:30,471,056...30,474,486
Ensembl chr17:30,470,855...30,474,590
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G |
CTLA4 |
cytotoxic T-lymphocyte associated protein 4 |
disease_progression |
ISO |
associated with Mammary Neoplasms, Experimental |
RGD |
PMID:15701862 PMID:18049334 |
RGD:4891518 RGD:7204722 |
NCBI chr15:107,283,081...107,288,041
Ensembl chr15:107,282,927...107,289,103
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G |
CTNNB1 |
catenin beta 1 |
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ISO |
associated with Prostatic Neoplasms CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:18008331 PMID:29106415 |
RGD:2289488 |
NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311
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G |
CTSB |
cathepsin B |
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ISO |
protein:increased expression:cerebrospinal fluid |
RGD |
PMID:12589965 |
RGD:5686394 |
NCBI chr14:15,014,139...15,035,081
Ensembl chr14:15,011,711...15,033,877
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G |
CTSD |
cathepsin D |
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ISO |
protein:increased expression:oral cavity, oropharynx, hypopharynx (human) |
RGD |
PMID:10562684 |
RGD:1547892 |
NCBI chr 2:1,188,548...1,197,642
Ensembl chr 2:1,188,549...1,197,643
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G |
CTSH |
cathepsin H |
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ISO |
protein:increased expression:cerebrospinal fluid |
RGD |
PMID:12589965 |
RGD:5686394 |
NCBI chr 7:48,084,882...48,106,072
Ensembl chr 7:48,083,572...48,106,072
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G |
CTU2 |
cytosolic thiouridylase subunit 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27811057 |
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NCBI chr 6:964,551...976,881
Ensembl chr 6:964,566...976,832
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G |
CX3CR1 |
C-X3-C motif chemokine receptor 1 |
susceptibility |
ISO |
associated with Breast Neoplasms |
RGD |
PMID:16627550 |
RGD:4892015 |
NCBI chr13:23,944,386...23,957,567
Ensembl chr13:23,944,369...23,957,486
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G |
CXCL12 |
C-X-C motif chemokine ligand 12 |
treatment |
ISO |
associated with Pancreatic Carcinoma associated with Pancreatic Neoplasms CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:12761880 PMID:21312072 PMID:23743303 PMID:26330165 |
RGD:10398726 RGD:2317610 |
NCBI chr14:91,516,383...91,543,857
Ensembl chr14:91,516,431...91,552,752
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G |
CXCR3 |
C-X-C motif chemokine receptor 3 |
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ISO |
associated with Mammary Neoplasms, Experimental |
RGD |
PMID:16885372 |
RGD:5135487 |
NCBI chr X:57,592,032...57,595,706
Ensembl chr X:57,592,038...57,595,692
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G |
CXCR4 |
C-X-C motif chemokine receptor 4 |
ameliorates disease_progression severity |
ISO |
CTD Direct Evidence: marker/mechanism associated with Otorhinolaryngologic Neoplasms;mRNA,protein:increased expression:Laryngeal and hypopharyngeal tissue (human) associated with lung non-small cell carcinoma;mRNA,protein:increased expression:lung (human) associated with oral squamous cell carcinoma associated with lung non-small cell carcinoma; protein:increased expression:lung (human) associated with pancreatic cancer associated with lung cancer; human cells in mouse model human cells in mouse model;associated with lung cancer associated with osteosarcoma;protein:increased expression:bone (human) |
CTD RGD |
PMID:16230077 PMID:16322285 PMID:17634424 PMID:18487224 PMID:21312072 PMID:23743303 PMID:24932250 PMID:25504108 PMID:26546437 PMID:28000861 PMID:32037613 More...
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RGD:151708730 RGD:152023741 RGD:152023745 RGD:152023746 RGD:152025556 RGD:152177475 RGD:152177476 RGD:152177478 RGD:152177479 |
NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,232
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G |
CYP19A3 |
cytochrome P450 19A3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28112739 |
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NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899
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G |
DAB2IP |
DAB2 interacting protein |
severity |
ISO |
associated with colorectal cancer;protein:decreased expression:colorectum (human) |
RGD |
PMID:26336990 |
RGD:11531913 |
NCBI chr 1:261,732,280...261,859,833
Ensembl chr 1:261,659,660...261,859,022
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G |
DAPK1 |
death associated protein kinase 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17319784 |
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NCBI chr10:27,724,644...27,954,708
Ensembl chr10:27,724,648...27,954,350
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G |
DAXX |
death domain associated protein |
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ISO |
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RGD |
PMID:23539629 |
RGD:9587820 |
NCBI chr 7:29,676,854...29,681,145
Ensembl chr 7:29,676,856...29,681,110
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G |
DCN |
decorin |
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ISO |
associated with Breast Neoplasms |
RGD |
PMID:18688028 |
RGD:2311418 |
NCBI chr 5:91,678,601...91,713,925
Ensembl chr 5:91,682,658...91,714,235
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G |
DDR1 |
discoidin domain receptor tyrosine kinase 1 |
severity |
ISO |
mRNA:increased expression:ovary (human) protein:increased expression:bone (human) |
RGD |
PMID:28743276 PMID:29039472 |
RGD:151347541 RGD:151347601 |
NCBI chr 7:23,371,358...23,391,585
Ensembl chr 7:23,373,845...23,391,584
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G |
DDR2 |
discoidin domain receptor tyrosine kinase 2 |
ameliorates |
ISO |
associated with melanoma; |
RGD |
PMID:24293323 |
RGD:150429711 |
NCBI chr 4:87,749,738...87,911,818
Ensembl chr 4:87,756,168...87,911,296
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G |
DDX3X |
DEAD-box helicase 3 X-linked |
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ISO |
human cells in mouse model |
RGD |
PMID:26087195 |
RGD:11096798 |
NCBI chr X:36,988,031...37,005,496
Ensembl chr X:36,988,031...37,018,202
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G |
DEK |
DEK proto-oncogene |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27811057 |
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NCBI chr 7:13,901,562...13,935,477
Ensembl chr 7:13,872,775...13,935,173
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G |
DHFR |
dihydrofolate reductase |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:8149482 PMID:19159907 |
RGD:11040442 |
NCBI chr 2:89,230,660...89,255,830
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G |
DIO3 |
iodothyronine deiodinase 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26825960 |
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G |
DMD |
dystrophin |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24793134 |
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NCBI chr X:27,028,223...29,650,728
Ensembl chr X:27,028,231...28,383,840
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G |
DNMT3B |
DNA methyltransferase 3 beta |
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ISO |
associated with Uterine Cervical Neoplasms; |
RGD |
PMID:22330137 |
RGD:9589117 |
NCBI chr17:36,345,715...36,386,076
Ensembl chr17:36,345,816...36,386,072
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G |
DPYD |
dihydropyrimidine dehydrogenase |
treatment |
ISO |
CTD Direct Evidence: marker/mechanism associated with Colonic Neoplasms |
CTD RGD |
PMID:11383214 PMID:17611699 |
RGD:11251755 |
NCBI chr 4:119,931,471...120,712,461
Ensembl chr 4:119,931,414...120,712,459
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G |
E2F1 |
E2F transcription factor 1 |
severity |
ISO |
protein:increased expression:bone (human) |
RGD |
PMID:29039472 |
RGD:151347601 |
NCBI chr17:37,178,587...37,190,118
Ensembl chr17:37,178,599...37,189,883
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G |
E2F8 |
E2F transcription factor 8 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27683099 |
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NCBI chr 2:40,178,182...40,194,932
Ensembl chr 2:40,178,177...40,194,935
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G |
EDN1 |
endothelin 1 |
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ISO |
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RGD |
PMID:12941866 |
RGD:734914 |
NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348
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G |
EDNRA |
endothelin receptor type A |
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ISO |
associated with Bladder Neoplasms |
RGD |
PMID:21183790 |
RGD:4892282 |
NCBI chr 8:81,210,750...81,279,053
Ensembl chr 8:81,209,327...81,276,853
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G |
EEF1B2 |
eukaryotic translation elongation factor 1 beta 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17085005 PMID:20562527 |
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NCBI chr15:109,451,901...109,455,529
Ensembl chr15:109,451,514...109,455,525
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G |
EEF2 |
eukaryotic translation elongation factor 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20562527 |
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NCBI chr 2:74,746,541...74,756,687
Ensembl chr 2:74,747,080...74,756,680
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G |
EFNB2 |
ephrin B2 |
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ISO |
associated with cholangiocarcinoma;protein:increased expression:biliary ductule (human) |
RGD |
PMID:25012246 |
RGD:153305948 |
NCBI chr11:74,188,337...74,232,768
Ensembl chr11:74,186,640...74,233,354
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G |
EGF |
epidermal growth factor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21942447 PMID:23064031 |
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NCBI chr 8:112,235,607...112,330,062
Ensembl chr 8:112,234,386...112,330,046
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G |
EGFR |
epidermal growth factor receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17369752 PMID:17575224 PMID:23867902 |
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NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589
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G |
EHMT2 |
euchromatic histone lysine methyltransferase 2 |
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ISO |
CTD Direct Evidence: marker/mechanism associated with lung neoplasms; |
CTD RGD |
PMID:20940408 PMID:25115793 |
RGD:9589170 |
NCBI chr 7:23,977,683...23,992,673
Ensembl chr 7:23,977,683...23,993,478
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G |
EIF1AX |
eukaryotic translation initiation factor 1A X-linked |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17085005 |
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NCBI chr X:16,429,625...16,449,581
Ensembl chr X:16,429,628...16,449,556
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G |
EIF4A2 |
eukaryotic translation initiation factor 4A2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17085005 |
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NCBI chr13:124,582,822...124,589,296
Ensembl chr13:124,582,898...124,589,293
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G |
ELP3 |
elongator acetyltransferase complex subunit 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27811057 |
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NCBI chr14:11,832,947...11,940,080
Ensembl chr14:11,832,962...11,940,070
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G |
EML4 |
EMAP like 4 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22986231 PMID:22999080 |
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NCBI chr 3:98,005,809...98,155,876
Ensembl chr 3:98,005,812...98,155,846
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G |
ENPP2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26037280 |
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NCBI chr 4:19,319,815...19,433,492
Ensembl chr 4:19,319,810...19,433,488
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G |
EPCAM |
epithelial cell adhesion molecule |
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ISO |
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RGD |
PMID:23390083 |
RGD:9685143 |
NCBI chr 3:93,169,800...93,185,221
Ensembl chr 3:93,168,852...93,185,653
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G |
EPO |
erythropoietin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16699298 |
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NCBI chr 3:8,620,508...8,622,936
Ensembl chr 3:8,620,508...8,622,936
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G |
EPOR |
erythropoietin receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16699298 |
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NCBI chr 2:70,063,601...70,068,821
Ensembl chr 2:70,063,519...70,068,821
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G |
ERBB2 |
erb-b2 receptor tyrosine kinase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism rat gene in a mouse model |
CTD RGD |
PMID:11238891 PMID:16984552 |
RGD:734938 |
NCBI chr12:22,591,621...22,621,384
Ensembl chr12:22,590,725...22,621,351
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G |
ERBB3 |
erb-b2 receptor tyrosine kinase 3 |
disease_progression |
ISO |
associated with Prostatic Neoplasms;protein:alternative form associated with lung adenocarcinoma CTD Direct Evidence: marker/mechanism associated with Prostatic Neoplasms;protein:increased expression, altered localization:bone, nucleus |
RGD CTD |
PMID:17634423 PMID:18559590 PMID:26254096 PMID:28114269 |
RGD:126790470 RGD:2289944 RGD:2298500 |
NCBI chr 5:21,474,218...21,495,040
Ensembl chr 5:21,474,475...21,495,038
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G |
ERBB4 |
erb-b2 receptor tyrosine kinase 4 |
disease_progression |
ISO |
associated with lung adenocarcinoma |
RGD |
PMID:26254096 |
RGD:126790470 |
NCBI chr15:113,966,573...115,096,984
Ensembl chr15:113,974,437...115,096,565
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G |
ERCC1 |
ERCC excision repair 1, endonuclease non-catalytic subunit |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism associated with Melanoma |
CTD RGD |
PMID:20801905 PMID:26202595 |
RGD:11252177 |
NCBI chr 6:51,783,537...51,808,898
Ensembl chr 6:51,783,478...51,798,984
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G |
ERCC4 |
ERCC excision repair 4, endonuclease catalytic subunit |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20372803 |
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NCBI chr 3:29,266,234...29,306,109
Ensembl chr 3:29,269,989...29,306,151
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G |
ERP29 |
endoplasmic reticulum protein 29 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17085005 |
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NCBI chr14:39,687,028...39,695,748
Ensembl chr14:39,687,000...39,695,752
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G |
ESR1 |
estrogen receptor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20104649 PMID:35044086 |
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NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363
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G |
ETV4 |
ETS variant transcription factor 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27869830 |
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NCBI chr12:19,531,507...19,548,303
Ensembl chr12:19,531,603...19,548,301
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G |
EZH2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
|
ISO |
associated with lung non-small cell carcinoma associated with stomach cancer;protein:increased expression:stomach associated with osteosarcoma |
RGD |
PMID:20132185 PMID:24097870 PMID:26265454 |
RGD:11532507 RGD:126779607 RGD:126781716 |
NCBI chr 9:109,384,976...109,450,943
Ensembl chr 9:109,385,015...109,450,941
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G |
EZR |
ezrin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27137931 |
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NCBI chr 1:8,403,362...8,452,750
Ensembl chr 1:8,403,453...8,452,742
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G |
F2 |
coagulation factor II, thrombin |
|
ISO |
associated with Carcinoma, Small cell;protein:increased expression:brain |
RGD |
PMID:22065054 |
RGD:6893520 |
NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137
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G |
FADD |
Fas associated via death domain |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16450001 |
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NCBI chr 2:3,191,718...3,194,820
Ensembl chr 2:3,185,675...3,194,818
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G |
FAS |
Fas cell surface death receptor |
|
ISO |
associated with Breast Neoplasms;protein:decreased expression:breast associated with Mammary Neoplasms;protein:decreased expression:lung |
RGD |
PMID:17352235 PMID:17918178 |
RGD:2290048 RGD:2290053 |
NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716
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G |
FASLG |
Fas ligand |
|
ISO |
associated with Breast Neoplasms;protein:decreased expression:breast |
RGD |
PMID:17352235 |
RGD:2290053 |
NCBI chr 9:115,068,314...115,075,147
Ensembl chr 9:115,068,090...115,076,464
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G |
FGF13 |
fibroblast growth factor 13 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19917848 |
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NCBI chr X:113,460,191...113,955,691
Ensembl chr X:113,460,191...113,932,715
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G |
FGFR1 |
fibroblast growth factor receptor 1 |
|
ISO |
associated with prostate adenocarcinoma |
RGD |
PMID:23576558 |
RGD:13504748 |
NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,724
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G |
FLT1 |
fms related receptor tyrosine kinase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21975929 |
|
NCBI chr11:5,620,698...5,797,095
Ensembl chr11:5,621,212...5,795,264
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|
G |
FN1 |
fibronectin 1 |
treatment |
ISO |
associated with stomach cancer; human cells in mouse model |
RGD |
PMID:27431311 |
RGD:152995400 |
NCBI chr15:117,658,158...117,737,145
Ensembl chr15:117,658,099...117,731,014
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|
G |
FSCN1 |
fascin actin-bundling protein 1 |
|
ISO |
associated with Pancreatic Neoplasms |
RGD |
PMID:15626919 |
RGD:2317788 |
NCBI chr 3:4,134,173...4,143,275
Ensembl chr 3:4,134,177...4,143,286
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|
G |
FTL |
ferritin light chain |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17085005 |
|
NCBI chr 6:54,231,121...54,232,756
Ensembl chr 6:54,231,172...54,232,750
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|
G |
GAB2 |
GRB2 associated binding protein 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21996746 |
|
NCBI chr 9:12,663,658...12,851,423
Ensembl chr 9:12,663,657...12,851,342
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|
G |
GDF15 |
growth differentiation factor 15 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23996089 |
|
NCBI chr 2:59,409,035...59,411,356
Ensembl chr 2:59,408,904...59,411,358
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|
G |
GJB1 |
gap junction protein beta 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17978847 |
|
NCBI chr X:57,241,990...57,249,496
Ensembl chr X:57,242,045...57,249,885
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|
G |
GP1BA |
glycoprotein Ib platelet subunit alpha |
|
ISO |
associated with Melanoma, Experimental |
RGD |
PMID:19727118 |
RGD:10450866 |
NCBI chr12:51,975,810...51,979,428
Ensembl chr12:51,975,874...51,977,757
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|
G |
GPCPD1 |
glycerophosphocholine phosphodiesterase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25482527 |
|
NCBI chr17:14,420,656...14,476,223
Ensembl chr17:14,420,658...14,476,212
|
|
G |
GPI |
glucose-6-phosphate isomerase |
|
ISO |
|
RGD |
PMID:20978190 |
RGD:11051956 |
NCBI chr 6:44,038,374...44,069,331
Ensembl chr 6:44,038,357...44,069,328
|
|
G |
GPX2 |
glutathione peroxidase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23867582 |
|
NCBI chr 7:89,007,636...89,011,620
Ensembl chr 7:89,007,375...89,011,620
|
|
G |
HABP2 |
hyaluronan binding protein 2 |
treatment |
ISO |
associated with Thyroid Neoplasms |
RGD |
PMID:22715430 |
RGD:11353856 |
NCBI chr14:123,893,990...123,929,445
Ensembl chr14:123,893,996...123,932,961
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|
G |
HAVCR2 |
hepatitis A virus cellular receptor 2 |
disease_progression |
ISO |
DNA:polymorphisms: : +4259T>G (human) |
RGD |
PMID:22472081 |
RGD:7245505 |
NCBI chr16:66,138,157...66,160,568
Ensembl chr16:66,139,535...66,160,538
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|
G |
HDAC3 |
histone deacetylase 3 |
|
ISO |
associated with Anaphylaxis; CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:24619412 PMID:34973135 |
RGD:9590165 |
NCBI chr 2:143,273,188...143,287,421
Ensembl chr 2:143,273,192...143,287,399
|
|
G |
HGF |
hepatocyte growth factor |
|
ISO |
associated with Pancreatic Neoplasms CTD Direct Evidence: marker/mechanism associated with Mammary Neoplasms, Experimental; associated with Melanoma; |
RGD CTD |
PMID:10688652 PMID:11893931 PMID:16459153 PMID:25971889 |
RGD:2317904 RGD:8548538 RGD:8548625 |
NCBI chr 9:98,437,771...98,513,573
Ensembl chr 9:98,438,143...98,513,564
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|
G |
HPSE |
heparanase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22240343 |
|
NCBI chr 8:135,082,199...135,120,887
Ensembl chr 8:135,097,725...135,120,887
|
|
G |
HRH2 |
histamine receptor H2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:6224980 |
|
NCBI chr 2:81,883,670...81,932,464
Ensembl chr 2:81,883,673...81,932,275
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|
G |
HSP90AA1 |
heat shock protein 90 alpha family class A member 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20562527 |
|
|
|
G |
IBSP |
integrin binding sialoprotein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22407340 PMID:24980816 |
|
NCBI chr 8:131,208,281...131,222,048
Ensembl chr 8:131,208,282...131,241,266
|
|
G |
ICAM1 |
intercellular adhesion molecule 1 |
|
ISO |
associated with Melanoma, Cutaneous Malignant associated with Pancreatic Neoplasms;protein:increased expression:serum |
RGD |
PMID:10465581 PMID:12923961 |
RGD:2325163 RGD:8547593 |
NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
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|
G |
ID1 |
inhibitor of DNA binding 1 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:24910342 |
|
NCBI chr17:35,316,518...35,317,742
Ensembl chr17:35,316,514...35,317,736
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|
G |
IGF1 |
insulin like growth factor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism associated with Uveal Melanoma;protein:increased expression:serum: associated with Pancreatic Neoplasms |
CTD RGD |
PMID:18398872 PMID:19375852 PMID:23197685 |
RGD:2317643 RGD:8548834 |
NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
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|
G |
IGF1R |
insulin like growth factor 1 receptor |
|
ISO |
associated with Pancreatic Neoplasms |
RGD |
PMID:16575403 |
RGD:2317645 |
NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058
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|
G |
IGF2 |
insulin like growth factor 2 |
|
ISO |
associated with Arthritis, Experimental; protein:increased expression:lung, bone, serum: |
RGD |
PMID:21859454 |
RGD:5510000 |
NCBI chr 2:1,469,183...1,496,417
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|
G |
IKZF1 |
IKAROS family zinc finger 1 |
|
ISO |
associated with colorectal cancer;DNA:polymorphisms: |
RGD |
PMID:31320627 |
RGD:150540328 |
NCBI chr 9:136,372,202...136,464,942
Ensembl chr 9:136,372,725...136,464,940
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|
G |
IL10 |
interleukin 10 |
|
ISO |
|
RGD |
PMID:16035616 |
RGD:1598627 |
NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378
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|
G |
IL18 |
interleukin 18 |
|
ISO |
associated with breast cancer;protein:increased expression:serum CTD Direct Evidence: marker/mechanism associated with breast cancer;DNA:SNP:promoter:-137G>C (rs187238) (human) |
RGD CTD |
PMID:11215816 PMID:12209760 PMID:12748951 PMID:19152241 |
RGD:4889862 RGD:8655866 RGD:8655899 |
NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219
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|
G |
IL2 |
interleukin 2 |
treatment |
ISO |
associated with melanoma associated with melanoma; associated with neuroblastoma. CTD Direct Evidence: therapeutic |
RGD CTD |
PMID:8610104 PMID:8642346 PMID:9362156 PMID:17105418 |
RGD:14747043 RGD:14865005 RGD:8663438 |
NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609
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|
G |
IL6 |
interleukin 6 |
treatment |
ISO |
associated with stomach cancer, human cells in mouse model CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:21937440 PMID:26101800 PMID:28186964 |
RGD:127229952 |
NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263
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|
G |
ITGA6 |
integrin subunit alpha 6 |
|
ISO |
|
RGD |
PMID:13130099 |
RGD:1302259 |
NCBI chr15:78,504,108...78,591,779
Ensembl chr15:78,504,078...78,591,777
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|
G |
ITGB1 |
integrin subunit beta 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23562787 |
|
NCBI chr10:56,078,393...56,130,608
Ensembl chr10:56,078,396...56,173,326
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|
G |
ITGB3 |
integrin subunit beta 3 |
|
ISO |
mRNA, protein:increased expression:lung associated with renal cell carcinoma;DNA:missense mutation:cds:p.L33P (human) |
RGD |
PMID:16831169 PMID:21107114 |
RGD:5037225 RGD:6907406 |
NCBI chr12:16,694,466...16,752,228
Ensembl chr12:16,693,514...16,752,292
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|
G |
JAK2 |
Janus kinase 2 |
treatment |
ISO |
associated with stomach cancer, human cells in mouse model |
RGD |
PMID:28186964 |
RGD:127229952 |
NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148
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|
G |
JUP |
junction plakoglobin |
|
ISO |
associated with Ovarian Neoplasms |
RGD |
PMID:15619205 |
RGD:2301746 |
NCBI chr12:20,902,395...20,931,208
Ensembl chr12:20,901,396...20,931,210
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|
G |
KDM6A |
lysine demethylase 6A |
disease_progression |
ISO |
associated with lung adenocarcinoma;protein:increased expression:brain (human) |
RGD |
PMID:33291558 |
RGD:150429741 |
NCBI chr X:39,953,764...40,154,197
Ensembl chr X:39,953,814...40,154,029
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|
G |
KDR |
kinase insert domain receptor |
|
ISO |
associated with Carcinoma, Renal Cell |
RGD |
PMID:17465216 |
RGD:2301757 |
NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,122...41,856,336
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|
G |
KIF2C |
kinesin family member 2C |
disease_progression |
ISO |
associated with colorectal cancer |
RGD |
PMID:18506187 |
RGD:27372891 |
NCBI chr 6:166,556,765...166,577,904
Ensembl chr 6:166,556,776...166,577,904
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|
G |
KMT2B |
lysine methyltransferase 2B |
|
ISO |
associated with lung adenocarcinoma |
RGD |
PMID:33291558 |
RGD:150429741 |
NCBI chr 6:45,146,863...45,166,854
Ensembl chr 6:45,147,566...45,166,852
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|
G |
KMT2D |
lysine methyltransferase 2D |
disease_progression |
ISO |
associated with colorectal cancer;DNA:mutations:: |
RGD |
PMID:27875625 |
RGD:155582219 |
NCBI chr 5:15,049,827...15,091,622
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|
G |
KRAS |
KRAS proto-oncogene, GTPase |
disease_progression treatment |
ISO |
associated with colorectal cancer;DNA:mutation: : associated with stomach cancer; human cells in mouse model associated with colorectal cancer; DNA:mutation:cds: associated with Fibrosarcoma;mRNA,protein:decreased expression:: associated with colorectal cancer;DNA:mutations: : CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:3552201 PMID:8635384 PMID:26210240 PMID:27264476 PMID:27431311 PMID:29032374 More...
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RGD:11086960 RGD:11570402 RGD:14398745 RGD:14398751 RGD:152995400 |
NCBI chr 5:48,508,774...48,546,260
Ensembl chr 5:48,508,811...48,549,358
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|
G |
KRT20 |
keratin 20 |
|
ISO |
associated with Colorectal Neoplasms |
RGD |
PMID:10931219 |
RGD:2317676 |
NCBI chr12:21,584,683...21,593,583
Ensembl chr12:21,584,814...21,594,854
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|
G |
L1CAM |
L1 cell adhesion molecule |
treatment |
ISO |
associated with Lung Neoplasms; associated with Pancreatic Neoplasms; |
RGD |
PMID:22095073 PMID:22307136 |
RGD:11570404 RGD:11570503 |
NCBI chr X:124,595,649...124,618,292
Ensembl chr X:124,595,651...124,618,307
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|
G |
LAMC2 |
laminin subunit gamma 2 |
|
ISO |
associated with lung adenocarcinoma; |
RGD |
PMID:25591736 |
RGD:11075980 |
NCBI chr 9:124,427,545...124,499,672
Ensembl chr 9:124,435,807...124,495,351
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|
G |
LCN2 |
lipocalin 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24570342 |
|
NCBI chr 1:268,609,975...268,614,651
Ensembl chr 1:268,609,887...268,614,644
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|
G |
LECT2 |
leukocyte cell derived chemotaxin 2 |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:30453282 |
|
NCBI chr 2:138,109,537...138,120,285
Ensembl chr 2:138,109,351...138,124,464
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|
G |
LEF1 |
lymphoid enhancer binding factor 1 |
|
ISO |
associated with prostate cancer CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:27067790 PMID:27811057 |
RGD:11531513 |
NCBI chr 8:113,824,511...113,944,078
Ensembl chr 8:113,825,161...113,944,070
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G |
LGALS3 |
galectin 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:25882088 |
|
NCBI chr 1:184,478,639...184,496,155
Ensembl chr 1:184,478,710...184,497,951
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|
G |
LLGL2 |
LLGL scribble cell polarity complex component 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28114269 |
|
NCBI chr12:5,809,066...5,846,165
Ensembl chr12:5,809,069...5,846,162
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G |
LOC100511937 |
phosphatidylinositol 3-kinase regulatory subunit gamma |
|
ISO |
associated with Adenocarcinoma, Colon |
RGD |
PMID:24837077 |
RGD:13432045 |
NCBI chr 6:165,268,260...165,402,668
Ensembl chr 6:165,268,568...165,402,649
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|
G |
LOC100516084 |
cytoplasmic tRNA 2-thiolation protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27811057 |
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NCBI chr 6:58,388,646...58,396,509
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G |
LOC100524391 |
putative methyltransferase NSUN6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28114269 |
|
NCBI chr10:44,884,179...44,958,024
Ensembl chr10:44,891,257...44,958,004
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G |
LOC110255312 |
keratin, type I cytoskeletal 14 |
|
ISO |
mRNA:decreased expression:epithelial cell |
RGD |
PMID:9876218 |
RGD:1600180 |
NCBI chr12:21,074,965...21,079,393
Ensembl chr12:21,074,850...21,079,391
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G |
LOC396867 |
stefin A8 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20461718 |
|
NCBI chr13:138,216,027...138,226,397
Ensembl chr13:138,181,723...138,236,860
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G |
LY96 |
lymphocyte antigen 96 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22180778 |
|
NCBI chr 4:61,919,806...61,950,712
Ensembl chr 4:61,926,064...61,950,697
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G |
MACC1 |
MET transcriptional regulator MACC1 |
treatment |
ISO |
associated with stomach cancer; human cells in mouse model CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:27431311 PMID:36008464 |
RGD:152995400 |
NCBI chr 9:89,130,971...89,342,181
Ensembl chr 9:89,102,621...89,210,281
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G |
MAP2K4 |
mitogen-activated protein kinase kinase 4 |
disease_progression |
ISO |
associated with oral squamous cell carcinoma;mRNA, protein:increased expression:lymph node (human) |
RGD |
PMID:22165133 |
RGD:150429749 |
NCBI chr12:56,402,029...56,516,217
Ensembl chr12:56,402,075...56,516,238
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|
G |
MAPK1 |
mitogen-activated protein kinase 1 |
treatment |
ISO |
associated with prostate adenocarcinoma CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:22139534 PMID:22580338 |
RGD:13504820 |
NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513
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|
G |
MAPK3 |
mitogen-activated protein kinase 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22580338 |
|
NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
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G |
MAPK9 |
mitogen-activated protein kinase 9 |
|
ISO |
associated with Colorectal Neoplasms CTD Direct Evidence: therapeutic |
RGD CTD |
PMID:21779479 PMID:25205654 |
RGD:13217416 |
NCBI chr 2:78,338,466...78,399,108
Ensembl chr 2:78,338,376...78,399,100
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G |
MED28 |
mediator complex subunit 28 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21942447 |
|
NCBI chr 8:12,624,096...12,633,251
Ensembl chr 8:12,624,109...12,635,334
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G |
MET |
MET proto-oncogene, receptor tyrosine kinase |
disease_progression |
ISO |
associated with Squamous Cell Carcinoma of the Tongue; CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:20080979 PMID:21225626 PMID:22704061 |
RGD:8548616 |
NCBI chr18:29,426,044...29,541,526
Ensembl chr18:29,426,048...29,541,512
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G |
MIR100 |
microRNA mir-100 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
|
NCBI chr 9:49,157,909...49,157,988
Ensembl chr 9:49,157,909...49,157,988
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G |
MIR125A |
microRNA mir-125a |
|
ISO |
associated with stomach cancer; CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:19487542 PMID:30117667 |
RGD:21403678 |
NCBI chr 6:58,331,566...58,331,645
Ensembl chr 6:58,331,566...58,331,645
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G |
MIR130A |
microRNA mir-130a |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
|
NCBI chr 2:13,296,695...13,296,773
Ensembl chr 2:13,296,695...13,296,773
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G |
MIR136 |
microRNA mir-136 |
ameliorates |
ISO |
associated with stomach cancer;human cells in mouse model |
RGD |
PMID:28656883 |
RGD:153344628 |
NCBI chr 7:121,711,328...121,711,409
Ensembl chr 7:121,711,325...121,711,414
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|
G |
MIR148B |
microRNA mir-148b |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
|
NCBI chr 5:19,530,990...19,531,069
Ensembl chr 5:19,530,985...19,531,074
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G |
MIR152 |
microRNA mir-152 |
|
ISO |
associated with Castration-Resistant Prostatic Neoplasms |
RGD |
PMID:23574937 |
RGD:19165145 |
NCBI chr12:24,292,249...24,292,328
Ensembl chr12:24,292,251...24,292,336
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G |
MIR155 |
microRNA mir-155 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
RGD CTD |
PMID:19487542 PMID:27692344 PMID:27856635 |
RGD:21079446 |
NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902
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G |
MIR181C |
microRNA mir-181c |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
|
NCBI chr 2:65,279,950...65,280,036
Ensembl chr 2:65,279,944...65,280,040
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|
G |
MIR193A |
microRNA mir-193a |
exacerbates |
ISO |
associated with colorectal cancer; miRNA:decreased expression:colorectum (human) associated with lung non-small cell carcinoma; human cells in mouse model |
RGD |
PMID:24469061 PMID:25232258 PMID:30685413 |
RGD:153344566 RGD:153344592 RGD:153344599 |
NCBI chr12:43,336,969...43,337,048
Ensembl chr12:43,336,969...43,337,048
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G |
MIR19A |
microRNA mir-19a |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
|
NCBI chr11:60,734,939...60,735,020
Ensembl chr11:60,734,939...60,735,020
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|
G |
MIR205 |
microRNA mir-205 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
|
NCBI chr 9:133,517,078...133,517,146
Ensembl chr 9:133,517,078...133,517,146
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|
G |
MIR20A |
microRNA mir-20a |
|
ISO |
associated with colorectal cancer |
RGD |
PMID:27286257 |
RGD:25823157 |
NCBI chr11:60,735,109...60,735,179
Ensembl chr11:60,735,099...60,735,196
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|
G |
MIR20B-1 |
microRNA mir-20b-1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
|
NCBI chr X:110,113,980...110,114,059
Ensembl chr X:110,113,980...110,114,059
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|
G |
MIR21 |
microRNA mir-21 |
ameliorates treatment |
ISO |
human cells in mouse model;associated with breast cancer CTD Direct Evidence: marker/mechanism associated with prostate carcinoma; human cells in mouse model |
RGD CTD |
PMID:18270520 PMID:26101800 PMID:32736696 |
RGD:152998873 RGD:152998897 |
NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358
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G |
MIR221 |
microRNA mir-221 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
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NCBI chr X:40,571,068...40,571,137
Ensembl chr X:40,571,068...40,571,137
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G |
MIR222 |
microRNA mir-222 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
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NCBI chr X:40,571,808...40,571,887
Ensembl chr X:40,571,808...40,571,887
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G |
MIR224 |
microRNA mir-224 |
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ISO |
CTD Direct Evidence: marker/mechanism associated with colorectal cancer; mRNA:increased expression:colorectal mucosa: |
CTD RGD |
PMID:19487542 PMID:25919696 |
RGD:14398749 |
NCBI chr X:123,283,427...123,283,507
Ensembl chr X:123,283,427...123,283,507
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G |
MIR30A |
microRNA mir-30a |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
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NCBI chr 1:51,412,827...51,412,933
Ensembl chr 1:51,412,827...51,412,933
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G |
MIR30E |
microRNA mir-30e |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
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NCBI chr 6:170,429,841...170,429,920
Ensembl chr 6:170,429,841...170,429,920
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G |
MIR31 |
microRNA mir-31 |
disease_progression treatment |
ISO |
CTD Direct Evidence: marker/mechanism associated with colorectal cancer;RNA:increased expression:colorectum (human) associated with stomach cancer;human cells in mouse model |
CTD RGD |
PMID:19487542 PMID:26497852 PMID:27174918 PMID:30108104 |
RGD:153297776 RGD:153297806 RGD:153297811 |
NCBI chr 1:201,198,732...201,198,809
Ensembl chr 1:201,198,732...201,198,809
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G |
MIR335 |
microRNA mir-335 |
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ISO |
lung metastasis |
RGD |
PMID:21822301 |
RGD:14394425 |
NCBI chr18:18,341,580...18,341,659
Ensembl chr18:18,341,568...18,341,659
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G |
MIR342 |
microRNA mir-342 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
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NCBI chr 7:121,021,761...121,021,840
Ensembl chr 7:121,021,761...121,021,840
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G |
MIR34C-1 |
microRNA mir-34c-1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
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NCBI chr 9:39,280,278...39,280,357
Ensembl chr 9:39,280,278...39,280,357
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G |
MIR532 |
microRNA mir-532 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
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NCBI chr X:43,705,258...43,705,337
Ensembl chr X:43,705,258...43,705,337
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G |
MIR885 |
microRNA mir-885 |
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ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:27738331 |
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NCBI chr13:66,597,531...66,597,610
Ensembl chr13:66,597,531...66,597,610
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G |
MIR96 |
microRNA mir-96 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
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NCBI chr18:18,982,506...18,982,590
Ensembl chr18:18,982,506...18,982,590
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G |
MIR99A |
microRNA mir-99a |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
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NCBI chr13:181,302,483...181,302,562
Ensembl chr13:181,302,478...181,302,567
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G |
MIR99B |
microRNA mir-99b |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19487542 |
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NCBI chr 6:58,332,211...58,332,280
Ensembl chr 6:58,332,205...58,332,284
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G |
MKI67 |
marker of proliferation Ki-67 |
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ISO |
associated with Pancreatic Neoplasms |
RGD |
PMID:20388395 |
RGD:2317702 |
NCBI chr14:137,266,622...137,296,312
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G |
MLH1 |
mutL homolog 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17717427 |
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NCBI chr13:21,791,276...21,877,789
Ensembl chr13:21,791,203...21,877,757
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G |
MMP1 |
matrix metallopeptidase 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:12538496 PMID:19487542 PMID:22580338 PMID:23548910 |
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NCBI chr 9:33,411,738...33,420,205
Ensembl chr 9:33,411,065...33,420,076
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G |
MMP13 |
matrix metallopeptidase 13 |
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ISO |
associated with Carcinoma, Renal Cell;mRNA, protein:increased expression:bone |
RGD |
PMID:18709334 |
RGD:2306080 |
NCBI chr 9:33,549,003...33,616,700
Ensembl chr 9:33,549,008...33,561,162
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G |
MMP2 |
matrix metallopeptidase 2 |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism associated with Mammary Neoplasms, Animal;protein:increased expression:brain associated with pancreatic cancer; protein:increased expression, increased activity:pancreas associated with Gallbladder Neoplasms; protein:increased expression:gallbladder |
CTD RGD |
PMID:12173379 PMID:16158251 PMID:16475674 PMID:18398872 PMID:18665467 PMID:21209944 PMID:22321834 PMID:23707804 PMID:30603057 More...
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RGD:2325743 RGD:2325749 RGD:8547884 |
NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982
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G |
MMP24 |
matrix metallopeptidase 24 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27869830 |
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NCBI chr17:38,587,230...38,636,628
Ensembl chr17:38,588,081...38,636,627
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G |
MMP9 |
matrix metallopeptidase 9 |
severity disease_progression |
ISO |
associated with Mammary Neoplasms, Animal CTD Direct Evidence: marker/mechanism associated with osteosarcoma;protein:increased expression:bone (human) associated with pancreatic cancer; protein:increased expression, increased activity:pancreas associated with skin melanoma;DNA:missense mutation:cds:p.Q279R (human) associated with Mammary Neoplasms, Animal;protein:increased expression:brain associated with Mammary Neoplasms, Animal; associated with Arthritis, Experimental associated with Melanoma associated with carcinoma, pancreatic ductal; protein:increased expression:pancreas |
RGD CTD |
PMID:8912869 PMID:12173379 PMID:15659795 PMID:16033831 PMID:16158251 PMID:16475674 PMID:17346338 PMID:17378244 PMID:18676849 PMID:18930813 PMID:21209944 PMID:21859454 PMID:21942447 PMID:26546437 PMID:34626302 More...
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RGD:152023746 | |