RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Dehydration
Accession: DOID:9007993
browse the term
Definition: The condition that results from excessive loss of water from a living organism.
Synonyms: exact_synonym: Water Stress
primary_id: MESH:D003681
xref: EFO:0009385
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Avp
arginine vasopressin
IEP ISO
mRNA:increased expression:paraventricular hypothalamic nucleus, supraoptic nucleus CTD Direct Evidence: therapeutic
CTD RGD
PMID:2554359 PMID:17393298
RGD:2304139
NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
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Dmd
dystrophin
IEP
protein:decreased expression:neurohypophysial lobe:
RGD
PMID:9858364
RGD:12880360
NCBI chr X:47,272,324...49,504,219
Ensembl chr X:47,272,331...49,504,207
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Hap1
huntingtin-associated protein 1
ISO
RGD
PMID:11971876
RGD:1302538
NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126
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Nos1
nitric oxide synthase 1
IEP
RGD
PMID:16052497
RGD:13825136
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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Npy1r
neuropeptide Y receptor Y1
IEP
protein:increased expression:hypothalamus
RGD
PMID:16728491
RGD:1642311
NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
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Oxt
oxytocin/neurophysin I prepropeptide
IEP
mRNA:increased expression:paraventricular hypothalamic nucleus, supraoptic nucleus
RGD
PMID:17393298
RGD:2304139
NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
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P2ry2
purinergic receptor P2Y2
IEP
mRNA, protein:decreased expression:inner renal medulla
RGD
PMID:15687250
RGD:2316687
NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
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Pcsk1
proprotein convertase subtilisin/kexin type 1
IEP
associated with Protein-Energy Malnutrition; protein:increased expression:pituitary (rat)
RGD
PMID:12411741
RGD:2308904
NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434
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Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
IEP
RGD
PMID:17412804
RGD:1642352
NCBI chr X:14,580,036...14,583,478
Ensembl chr X:14,580,038...14,583,566
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Pdia3
protein disulfide isomerase family A, member 3
IEP
protein:increased expression:brain:
RGD
PMID:17412804
RGD:1642352
NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
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Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
IEP
mRNA, protein:increased expression:supraoptic nucleus, pituitary
RGD
PMID:17927670
RGD:9587478
NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
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