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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Colonic Diverticulosis
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Accession:DOID:9007768 term browser browse the term
Definition:A pathological condition characterized by the presence of a number of COLONIC DIVERTICULA in the COLON. Its pathogenesis is multifactorial, including colon aging, motor dysfunction, increases in intraluminal pressure, and lack of dietary fibers.
Synonyms:exact_synonym: diverticular disease
 primary_id: MESH:D043963
 xref: EFO:0009959



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diverticulitis of colon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd163 CD163 molecule exacerbates ISO protein:increased expression:sigmoid colon (human) RGD PMID:21553154 RGD:40925945 NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:157,085,093...157,117,878
JBrowse link
G Cd68 Cd68 molecule severity ISO associated with steroid use;protein:increased expression:sigmoid colon (human) RGD PMID:21553154 RGD:40925945 NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,381,815...54,383,697
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19134
    disease of anatomical entity 18447
      gastrointestinal system disease 7194
        intestinal disease 3105
          colonic disease 2323
            Colonic Diverticulosis 2
              Diverticulosis of Bowel, Hernia, and Retinal Detachment 0
              diverticulitis of colon 2
paths to the root