RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Craniocerebral Trauma
Accession: DOID:9007621
browse the term
Definition: Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage.
Synonyms: exact_synonym: Craniocerebral Injuries; Craniocerebral Injury; Craniocerebral Traumas; Crushing Skull Injuries; Crushing Skull Injury; Forehead Trauma; Forehead Traumas; Frontal Region Trauma; Frontal Region Traumas; Head Injuries; Head Injury; Head Trauma; Head Traumas; Minor Head Injuries; Minor Head Injury; Multiple Head Injuries; Multiple Head Injury; Occipital Region Trauma; Occipital Region Traumas; Occipital Trauma; Occipital Traumas; Open Head Injuries; Open Head Injury; Parietal Region Trauma; Parietal Region Traumas; Superficial Head Injuries; Superficial Head Injury; Temporal Region Trauma; Temporal Region Traumas
primary_id: MESH:D006259 ; RDO:0005059
xref: EFO:0009505
GViewer not supported for the selected species.
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Adnp
activity dependent neuroprotector homeobox
ISO
RGD
PMID:11123362
RGD:2312784
NCBI chrNW_004936514:3,855,113...3,883,036
Ensembl chrNW_004936514:3,855,672...3,885,718
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Il1a
interleukin 1 alpha
ISO
protein:increased expression:microglial cell
RGD
PMID:7830934
RGD:10045949
NCBI chrNW_004936783:1,210,715...1,218,315
Ensembl chrNW_004936783:1,210,809...1,218,315
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Postn
periostin
ISO
RGD
PMID:17878602
RGD:10041014
NCBI chrNW_004936472:31,644,778...31,677,572
Ensembl chrNW_004936472:31,644,778...31,677,572
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Serpinc1
serpin family C member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8810955
NCBI chrNW_004936481:13,981,014...13,993,750
Ensembl chrNW_004936481:13,981,019...13,993,634
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Epo
erythropoietin
treatment
ISO
RGD
PMID:23415790
RGD:10401075
NCBI chrNW_004936543:742,722...745,332
Ensembl chrNW_004936543:743,537...745,343
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F7
coagulation factor VII
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:12503044
NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339
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Kcnn4
potassium calcium-activated channel subfamily N member 4
treatment
ISO
RGD
PMID:15379997
RGD:329969897
NCBI chrNW_004936706:940,585...952,484
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Cfl1
cofilin 1
treatment
ISO
RGD
PMID:25708984
RGD:12738361
NCBI chrNW_004936599:3,678,724...3,682,314
Ensembl chrNW_004936599:3,677,804...3,682,307
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Drd2
dopamine receptor D2
ISO
RGD
PMID:26448536
RGD:13506960
NCBI chrNW_004936612:1,094,686...1,154,149
Ensembl chrNW_004936612:1,094,680...1,154,798
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Drd3
dopamine receptor D3
ISO
RGD
PMID:26448536
RGD:13506960
NCBI chrNW_004936536:1,580,732...1,616,726
Ensembl chrNW_004936536:1,580,732...1,616,725
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Drd4
dopamine receptor D4
ISO
RGD
PMID:26448536
RGD:13506960
NCBI chrNW_004936888:468,334...471,254
Ensembl chrNW_004936888:468,403...471,205
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Il6
interleukin 6
treatment
ISO
RGD
PMID:27113205
RGD:11062140
NCBI chrNW_004936549:7,015,595...7,016,246
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C3
complement C3
ameliorates
ISO
RGD
PMID:31654641
RGD:408418727
NCBI chrNW_004936588:3,985,732...4,023,221
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Casp3
caspase 3
treatment
ISO
RGD
PMID:28140659
RGD:13782305
NCBI chrNW_004936554:4,571,072...4,593,765
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Casp8
caspase 8
treatment
ISO
RGD
PMID:28140659
RGD:13782305
NCBI chrNW_004936726:554,627...596,334
Ensembl chrNW_004936726:554,758...595,922
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Il1b
interleukin 1 beta
treatment
ISO
RGD
PMID:31654641
RGD:408418727
NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165
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Pycard
PYD and CARD domain containing
treatment
ISO
RGD
PMID:19401709
RGD:5491174
NCBI chrNW_004936501:13,550,702...13,552,774
Ensembl chrNW_004936501:13,550,679...13,552,805
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Tnf
tumor necrosis factor
treatment
ISO
RGD
PMID:31654641
RGD:408418727
NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
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Abcc8
ATP binding cassette subfamily C member 8
treatment
ISO
RGD
PMID:21107131
RGD:12791995
NCBI chrNW_004936528:1,608,782...1,682,873
Ensembl chrNW_004936528:1,608,757...1,682,975
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Acan
aggrecan
ISO
mRNA:increased expression:fascia dentata (rat)
RGD
PMID:18511192
RGD:2315807
NCBI chrNW_004936483:14,811,152...14,846,305
Ensembl chrNW_004936483:14,811,152...14,846,305
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Actr2
actin related protein 2
ISO
mRNA, protein:decreased expression:hippocampus (rat)
RGD
PMID:22120305
RGD:11530046
NCBI chrNW_004936491:9,980,228...10,021,417
Ensembl chrNW_004936491:9,979,427...10,022,043
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Adcyap1
adenylate cyclase activating polypeptide 1
ISO
RGD
PMID:16689670
RGD:2325298
NCBI chrNW_004936672:3,461,387...3,468,053
Ensembl chrNW_004936672:3,460,383...3,468,255
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Adra1a
adrenoceptor alpha 1A
ISO
mRNA:increased expression:frontal cortex
RGD
PMID:20974230
RGD:5688366
NCBI chrNW_004936757:149,366...237,710
Ensembl chrNW_004936757:150,496...237,710
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Ager
advanced glycosylation end-product specific receptor
ISO
protein:increased expression:brain (rat)
RGD
PMID:22491548 PMID:22915134 PMID:24859607
RGD:7245513 RGD:7245557 RGD:8696001
NCBI chrNW_004936727:1,418,342...1,422,005
Ensembl chrNW_004936727:1,418,799...1,422,147
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Aif1
allograft inflammatory factor 1
ISO
protein:increased expression:cerebral cortex (rat)
RGD
PMID:19520144
RGD:2313020
NCBI chrNW_004936727:1,907,493...1,909,350
Ensembl chrNW_004936727:1,907,505...1,909,338
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Aifm1
apoptosis inducing factor mitochondria associated 1
ISO
protein:increased expression:nucleus:
RGD
PMID:12091479
RGD:10053567
NCBI chrNW_004936479:1,441,508...1,477,133
Ensembl chrNW_004936479:1,441,437...1,478,107
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Akt1
AKT serine/threonine kinase 1
ISO
protein:increased phosphorylation:brain, neuron
RGD
PMID:16234845
RGD:5509090
NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093
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Ambp
alpha-1-microglobulin/bikunin precursor
ISO
protein:increased expression:urine
RGD
PMID:14592616
RGD:6904155
NCBI chrNW_004936487:3,399,792...3,412,088
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Ank3
ankyrin 3
ISO
RGD
PMID:20557305
RGD:6767288
NCBI chrNW_004936614:2,664,594...2,976,174
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Anp32a
acidic nuclear phosphoprotein 32 family member A
ISO
RGD
PMID:24385964
RGD:10401136
NCBI chrNW_004936471:28,601,816...28,635,002
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Apaf1
apoptotic peptidase activating factor 1
ISO
protein:increased expression:cerebral cortex
RGD
PMID:11567033
RGD:2325751
NCBI chrNW_004936492:14,818,561...14,902,231
Ensembl chrNW_004936492:14,816,623...14,902,132
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Apbb1
amyloid beta precursor protein binding family B member 1
ISO
mRNA:increased expression:brain
RGD
PMID:12707777
RGD:2301208
NCBI chrNW_004936842:452,682...476,533
Ensembl chrNW_004936842:452,681...476,513
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Apex1
apurinic/apyrimidinic endodeoxyribonuclease 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11447995
NCBI chrNW_004936877:666,545...669,351
Ensembl chrNW_004936877:666,523...669,338
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Apod
apolipoprotein D
ISO
mRNA, protein:increased expression:cerebral cortex, glia cell, neuron
RGD
PMID:10501208
RGD:2311202
NCBI chrNW_004936833:260,798...277,060
Ensembl chrNW_004936833:259,660...277,246
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App
amyloid beta precursor protein
ISO
protein:increased expression:hippocampus
RGD
PMID:16300758
RGD:10054281
NCBI chrNW_004936640:1,549,977...1,787,436
Ensembl chrNW_004936640:1,550,167...1,787,286
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Aqp4
aquaporin 4
ISO
protein:increased expression:cerebral cortex
RGD
PMID:21083433 PMID:21488209
RGD:5148014 RGD:5148034
NCBI chrNW_004936550:5,931,201...5,943,999
Ensembl chrNW_004936550:5,931,194...5,941,354
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Asic1
acid sensing ion channel subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21307247
NCBI chrNW_004936512:7,720,591...7,746,557
Ensembl chrNW_004936512:7,720,523...7,746,579
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Astn1
astrotactin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:14499481
NCBI chrNW_004936481:11,461,091...11,743,376
Ensembl chrNW_004936481:11,461,009...11,743,386
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Atg12
autophagy related 12
ISO
protein:altered localization:brain
RGD
PMID:18059433
RGD:2301217
NCBI chrNW_004936742:1,000,029...1,007,885
Ensembl chrNW_004936742:999,771...1,007,885
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Atp5pd
ATP synthase peripheral stalk subunit d
treatment
ISO
RGD
PMID:26813465
RGD:13800884
NCBI chrNW_004936594:354,416...359,415
Ensembl chrNW_004936594:353,980...359,414
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Avpr1a
arginine vasopressin receptor 1A
ISO
mRNA:increased expression:cerebral cortex
RGD
PMID:17244947
RGD:2300372
NCBI chrNW_004936545:1,788,995...1,795,842
Ensembl chrNW_004936545:1,786,571...1,794,709
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Bad
BCL2 associated agonist of cell death
ISO
mRNA, protein:increased expression:cerebral cortex
RGD
PMID:15941375
RGD:2292694
NCBI chrNW_004936599:4,924,349...4,933,683
Ensembl chrNW_004936599:4,924,789...4,933,368
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Bax
BCL2 associated X, apoptosis regulator
treatment
ISO
RGD
PMID:20888848
RGD:10054247
NCBI chrNW_004936664:2,968,103...2,973,652
Ensembl chrNW_004936664:2,967,865...2,973,820
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Bcat1
branched chain amino acid transaminase 1
ISO
Protein:increased expression:neurons
RGD
PMID:10686349
RGD:631308
NCBI chrNW_004936548:2,385,756...2,454,423
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Bcl2
BCL2 apoptosis regulator
treatment
ISO
RGD
PMID:18093155 PMID:20888848
RGD:10054247 RGD:2293059
NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921
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Bdnf
brain derived neurotrophic factor
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
RGD CTD
PMID:15500971 PMID:20544832 PMID:21269288
RGD:4891136
NCBI chrNW_004936540:5,530,081...5,582,765
Ensembl chrNW_004936540:5,529,942...5,585,014
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Becn1
beclin 1
ISO
protein:increased expression:brain CTD Direct Evidence: therapeutic protein:increased expression:neuron, astrocyte protein:increased expression:hippocampus
RGD CTD
PMID:16874043 PMID:18500386 PMID:24221859 PMID:34929507
RGD:11558018 RGD:6483098 RGD:6483314
NCBI chrNW_004936490:17,518,100...17,531,126
Ensembl chrNW_004936490:17,517,751...17,531,151
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Birc5
baculoviral IAP repeat containing 5
ISO
mRNA, protein:increased expression:brain, astrocyte, neuron
RGD
PMID:15453988
RGD:2293136
NCBI chrNW_004936594:2,812,165...2,820,618
Ensembl chrNW_004936594:2,812,238...2,820,636
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Bmp6
bone morphogenetic protein 6
ISO
protein:increased expression:brain, astrocyte, neuron
RGD
PMID:16388909
RGD:2289020
NCBI chrNW_004936534:4,707,658...4,871,865
Ensembl chrNW_004936534:4,709,064...4,871,023
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Bmpr2
bone morphogenetic protein receptor type 2
ISO
mRNA:increased expression:dentate gyrus, neuron
RGD
PMID:9080432
RGD:5129488
NCBI chrNW_004936726:1,543,263...1,711,422
Ensembl chrNW_004936726:1,543,245...1,704,541
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Bysl
bystin like
ISO
mRNA, protein:increased expression:substantia nigra, striatum (rat)
RGD
PMID:15305856
RGD:2316201
NCBI chrNW_004936476:17,887,998...17,896,598
Ensembl chrNW_004936476:17,888,335...17,896,268
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C1qa
complement C1q A chain
ISO
RGD
PMID:23808389
RGD:10054313
NCBI chrNW_004936474:8,007,953...8,010,591
Ensembl chrNW_004936474:8,008,534...8,010,191
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C3
complement C3
ISO
RGD
PMID:23808389
RGD:10054313
NCBI chrNW_004936588:3,985,732...4,023,221
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Cask
calcium/calmodulin dependent serine protein kinase
ISO
RGD
PMID:25089700
RGD:11576302
NCBI chrNW_004936502:7,933,312...8,281,492
Ensembl chrNW_004936502:7,937,146...8,281,492
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Casp3
caspase 3
treatment
ISO
RGD
PMID:20888848
RGD:10054247
NCBI chrNW_004936554:4,571,072...4,593,765
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Casp8
caspase 8
ISO
protein:altered localization
RGD
PMID:15590916
RGD:1624191
NCBI chrNW_004936726:554,627...596,334
Ensembl chrNW_004936726:554,758...595,922
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Cast
calpastatin
severity
ISO
mRNA:increased expression:cerebral cortex
RGD
PMID:15307896
RGD:5509821
NCBI chrNW_004936523:6,688,153...6,798,184
Ensembl chrNW_004936523:6,686,519...6,798,321
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Ccl20
C-C motif chemokine ligand 20
treatment
ISO
RGD
PMID:22040257
RGD:7483630
NCBI chrNW_004936525:8,238,128...8,240,974
Ensembl chrNW_004936525:8,237,831...8,240,974
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Cd14
CD14 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004936531:9,572,392...9,575,771
Ensembl chrNW_004936531:9,571,796...9,575,923
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Cd40
CD40 molecule
treatment
ISO
RGD
PMID:23924471
RGD:7248749
NCBI chrNW_004936514:6,936,915...6,947,246
Ensembl chrNW_004936514:6,936,572...6,947,280
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Cd40lg
CD40 ligand
treatment
ISO
RGD
PMID:11755016 PMID:25972624
RGD:11344972 RGD:8547803
NCBI chrNW_004936513:10,607,617...10,620,403
Ensembl chrNW_004936513:10,607,617...10,620,403
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Cdkn1a
cyclin dependent kinase inhibitor 1A
ISO
protein:increased expression:nucleus:
RGD
PMID:9914434
RGD:8662346
NCBI chrNW_004936476:22,717,308...22,725,127
Ensembl chrNW_004936476:22,717,260...22,725,182
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Cdkn1b
cyclin dependent kinase inhibitor 1B
ISO
protein:decreased expression:cerebral cortex
RGD
PMID:21728064
RGD:10045359
NCBI chrNW_004936587:4,573,166...4,578,480
Ensembl chrNW_004936587:4,572,728...4,578,461
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Cebpa
CCAAT enhancer binding protein alpha
ISO
mRNA, protein:increased expression:cerebral cortex (mouse)
RGD
PMID:19833158
RGD:10401206
NCBI chrNW_004936570:2,513,561...2,516,213
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Cfb
complement factor B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17474994
NCBI chrNW_004936727:1,595,872...1,602,274
Ensembl chrNW_004936727:1,595,499...1,602,215
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Chrm2
cholinergic receptor muscarinic 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936592:1,396,939...1,525,255
Ensembl chrNW_004936592:1,521,547...1,522,947
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Chrna7
cholinergic receptor nicotinic alpha 7 subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004937351:32,324...46,871
Ensembl chrNW_004937351:34,921...47,246
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Clec4e
C-type lectin domain family 4 member E
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004936858:316,954...321,668
Ensembl chrNW_004936858:316,954...321,668
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Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
ISO
protein:increased expression:hippocampus
RGD
PMID:20215974
RGD:6483336
NCBI chrNW_004936490:16,834,570...16,841,734
Ensembl chrNW_004936490:16,834,540...16,841,810
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Comt
catechol-O-methyltransferase
ISO
protein:increased expression:hippocampus
RGD
PMID:17240060
RGD:2289740
NCBI chrNW_004936619:3,847,059...3,883,866
Ensembl chrNW_004936619:3,876,299...3,882,747
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Crp
C-reactive protein
disease_progression
ISO
RGD
PMID:24456846
RGD:9585646
NCBI chrNW_004936740:885,855...888,854
Ensembl chrNW_004936740:883,272...890,606
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Csf2
colony stimulating factor 2
disease_progression
ISO
RGD
PMID:21515263
RGD:5686795
NCBI chrNW_004936647:3,081,896...3,083,864
Ensembl chrNW_004936647:3,081,896...3,083,864
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Csf3
colony stimulating factor 3
treatment
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:21549006 PMID:24239694
RGD:11039431
NCBI chrNW_004936490:15,142,526...15,146,375
Ensembl chrNW_004936490:15,142,808...15,144,487
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Cspg4
chondroitin sulfate proteoglycan 4
ISO
protein:altered expression:cerebral cortex
RGD
PMID:19473238
RGD:5686860
NCBI chrNW_004936471:34,438,676...34,475,005
Ensembl chrNW_004936471:34,438,676...34,475,052
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Cul5
cullin 5
ISO
mRNA, protein:decreased expression:cerebral cortex, hippocampus
RGD
PMID:17010517
RGD:2301432
NCBI chrNW_004936551:641,469...724,706
Ensembl chrNW_004936551:641,463...724,711
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Cxcl10
C-X-C motif chemokine ligand 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004936676:60,869...63,028
Ensembl chrNW_004936676:60,621...63,106
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Dab2
DAB adaptor protein 2
ISO
RGD
PMID:15774263
RGD:7243841
NCBI chrNW_004936518:2,915,819...2,936,474
Ensembl chrNW_004936518:2,915,764...2,937,875
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Dnmt1
DNA methyltransferase 1
ISO
RGD
PMID:19429151
RGD:9588608
NCBI chrNW_004936659:520,181...565,496
Ensembl chrNW_004936659:520,493...565,416
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Dpysl2
dihydropyrimidinase like 2
ISO
protein:increased degradation:cerebral cortex, hippocampus
RGD
PMID:17402852
RGD:2303056
NCBI chrNW_004936757:311,317...422,870
Ensembl chrNW_004936757:309,022...422,955
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Drd2
dopamine receptor D2
ISO
RGD
PMID:18509630
RGD:2311580
NCBI chrNW_004936612:1,094,686...1,154,149
Ensembl chrNW_004936612:1,094,680...1,154,798
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Dusp5
dual specificity phosphatase 5
ISO
mRNA:increased expression:cerebral cortex
RGD
PMID:12503083
RGD:2317873
NCBI chrNW_004936486:1,351,077...1,361,002
Ensembl chrNW_004936486:1,347,885...1,359,903
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Eif2s1
eukaryotic translation initiation factor 2 subunit alpha
ISO
RGD
PMID:11526986
RGD:10395358
NCBI chrNW_004936495:10,746,687...10,769,304
Ensembl chrNW_004936495:10,745,923...10,773,199
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Elk1
ETS transcription factor ELK1
ISO
RGD
PMID:15362724
RGD:7488910
NCBI chrNW_004936502:13,402,726...13,418,214
Ensembl chrNW_004936502:13,402,728...13,418,214
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Eno2
enolase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:34533065
NCBI chrNW_004936709:904,647...913,445
Ensembl chrNW_004936709:904,031...913,451
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Epas1
endothelial PAS domain protein 1
treatment
ISO
RGD
PMID:22960363
RGD:10395371
NCBI chrNW_004936508:5,855,748...5,938,879
Ensembl chrNW_004936508:5,855,732...5,938,856
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Epha4
EPH receptor A4
ISO
protein:increased expression, increased activity:astrocyte
RGD
PMID:22318127
RGD:5688763
NCBI chrNW_004936569:3,539,269...3,670,322
Ensembl chrNW_004936569:3,540,053...3,670,348
G
Ephx2
epoxide hydrolase 2
ISO
RGD
PMID:21075124
RGD:5688356
NCBI chrNW_004936675:350,357...392,919
Ensembl chrNW_004936675:350,342...392,551
G
Epo
erythropoietin
treatment
ISO
CTD Direct Evidence: therapeutic mRNA:increased expression:brain:
CTD RGD
PMID:18093155 PMID:20833152 PMID:23063952
RGD:10401061 RGD:2293059
NCBI chrNW_004936543:742,722...745,332
Ensembl chrNW_004936543:743,537...745,343
G
Epor
erythropoietin receptor
ISO
mRNA:increased expression:brain:
RGD
PMID:18093155
RGD:2293059
NCBI chrNW_004936659:1,468,391...1,473,880
Ensembl chrNW_004936659:1,468,634...1,473,880
G
F2
coagulation factor II, thrombin
severity
ISO
RGD
PMID:21355766
RGD:5147766
NCBI chrNW_004936562:2,371,725...2,388,617
Ensembl chrNW_004936562:2,372,044...2,388,650
G
Fas
Fas cell surface death receptor
ISO
associated with Hyperoxia mRNA:increased expression:hippocampus
RGD
PMID:16078565 PMID:19107989
RGD:1600354 RGD:8662854
NCBI chrNW_004936735:209,369...234,582
G
Fmr1
Fragile X messenger ribonucleoprotein 1
ISO
protein:altered localization:hippocampus (rat)
RGD
PMID:16510718
RGD:11667962
NCBI chrNW_004936513:1,290,038...1,327,850
Ensembl chrNW_004936513:1,289,558...1,327,856
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:9630518
NCBI chrNW_004936488:4,384,710...4,388,118
Ensembl chrNW_004936488:4,384,705...4,388,122
G
Foxp1
forkhead box P1
treatment
ISO
RGD
PMID:26842647
RGD:11561903
NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324
G
G6pd
glucose-6-phosphate dehydrogenase
ISO
protein:decreased expression:hippocampus
RGD
PMID:18501200
RGD:2307353
NCBI chrNW_004936809:1,269,900...1,285,853
Ensembl chrNW_004936809:1,269,914...1,285,889
G
Gabrb3
gamma-aminobutyric acid type A receptor subunit beta3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936471:39,791,633...40,193,049
Ensembl chrNW_004936471:39,791,613...40,187,923
G
Gabrg3
gamma-aminobutyric acid type A receptor subunit gamma3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936471:39,184,683...39,256,439
Ensembl chrNW_004936471:39,185,702...39,751,187
G
Gdnf
glial cell derived neurotrophic factor
ISO
mRNA:increased expression:brain
RGD
PMID:18501516
RGD:2324932
NCBI chrNW_004936518:4,291,391...4,310,752
Ensembl chrNW_004936518:4,288,154...4,310,753
G
Gja1
gap junction protein alpha 1
treatment
ISO
RGD
PMID:23485053
RGD:8662424
NCBI chrNW_004936658:3,920,043...3,932,987
Ensembl chrNW_004936658:3,920,043...3,932,987
G
Gja5
gap junction protein alpha 5
ISO
protein:increased expression:cerebral artery
RGD
PMID:21895483
RGD:7207391
NCBI chrNW_004936867:269,477...279,549
G
Gpx1
glutathione peroxidase 1
ISO
mRNA:decreased expression:hippocampus, neuron
RGD
PMID:15791111
RGD:2306624
NCBI chrNW_004936529:997,943...999,123
Ensembl chrNW_004936529:998,150...998,987
G
Grm8
glutamate metabotropic receptor 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936479:13,768,014...14,504,387
Ensembl chrNW_004936479:13,770,088...14,494,569
G
Gsk3b
glycogen synthase kinase 3 beta
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:22643085 PMID:24675465
RGD:10045646
NCBI chrNW_004936536:6,730,070...6,893,818
Ensembl chrNW_004936536:6,730,062...6,894,303
G
Gsn
gelsolin
ISO
RGD
PMID:14588109
RGD:1599864
NCBI chrNW_004936487:9,749,755...9,802,787
Ensembl chrNW_004936487:9,764,944...9,802,841
G
Hcn1
hyperpolarization activated cyclic nucleotide gated potassium channel 1
ISO
mRNA,protein:decreased expression:hippocampus:
RGD
PMID:11726545
RGD:9686434
NCBI chrNW_004936480:17,051,902...17,416,335
Ensembl chrNW_004936480:17,051,898...17,413,657
G
Hmgb1
high mobility group box 1
treatment
ISO
RGD
PMID:22915134
RGD:7245513
NCBI chrNW_004936472:25,236,728...25,246,585
Ensembl chrNW_004936472:25,236,728...25,246,580
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
ISO
RGD
PMID:18562561
RGD:5508455
NCBI chrNW_004936549:1,378,536...1,400,501
Ensembl chrNW_004936549:1,378,736...1,400,532
G
Hmox1
heme oxygenase 1
ISO
RGD
PMID:23470432
RGD:10755702
NCBI chrNW_004936492:5,042,353...5,049,216
Ensembl chrNW_004936492:5,042,330...5,049,311
G
Hspa4
heat shock protein family A (Hsp70) member 4
ISO
protein:increased expression:cerebral white matter (rat)
RGD
PMID:22067617
RGD:5688785
NCBI chrNW_004936647:2,087,650...2,133,343
Ensembl chrNW_004936647:2,087,604...2,133,355
G
Hspb1
heat shock protein family B (small) member 1
ISO
RGD
PMID:11746764
RGD:6480530
NCBI chrNW_004936543:2,110,351...2,111,896
Ensembl chrNW_004936543:2,110,304...2,112,186
G
Htr7
5-hydroxytryptamine receptor 7
ISO
RGD
PMID:22465320
RGD:6482178
NCBI chrNW_004936601:3,569,626...3,626,782
Ensembl chrNW_004936601:3,569,544...3,626,797
G
Icam1
intercellular adhesion molecule 1
ISO
protein:increased expression:brain:
RGD
PMID:16230799
RGD:11522716
NCBI chrNW_004936659:616,570...627,172
Ensembl chrNW_004936659:616,752...627,174
G
Igf1
insulin like growth factor 1
treatment
ISO
human protein in a rat model
RGD
PMID:9344566
RGD:12904928
NCBI chrNW_004936492:11,709,623...11,784,028
Ensembl chrNW_004936492:11,709,222...11,778,351
G
Igf2
insulin like growth factor 2
ISO
mRNA:decreased expression:brain
RGD
PMID:11123717
RGD:5509972
NCBI chrNW_004936816:972,902...981,232
Ensembl chrNW_004936816:972,282...979,167
G
Il10
interleukin 10
treatment severity
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:21549006 PMID:23075771 PMID:23971414
RGD:7364822 RGD:7364983
NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502
G
Il12rb2
interleukin 12 receptor subunit beta 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936591:4,238,720...4,310,847
G
Il13ra2
interleukin 13 receptor subunit alpha 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936499:860,179...883,884
Ensembl chrNW_004936499:863,599...883,855
G
Il16
interleukin 16
ISO
RGD
PMID:17983426
RGD:5024939
NCBI chrNW_004936483:19,417,580...19,512,654
Ensembl chrNW_004936483:19,418,086...19,512,639
G
Il17rd
interleukin 17 receptor D
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936473:7,447,292...7,507,819
Ensembl chrNW_004936473:7,447,292...7,507,830
G
Il18
interleukin 18
severity
ISO
mRNA, protein:increased expression:brain
RGD
PMID:17188500
RGD:2315917
NCBI chrNW_004936612:2,306,963...2,325,086
Ensembl chrNW_004936612:2,306,875...2,325,189
G
Il18r1
interleukin 18 receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936713:1,038,985...1,075,770
Ensembl chrNW_004936713:1,038,877...1,075,811
G
Il1a
interleukin 1 alpha
ISO
CTD Direct Evidence: marker/mechanism mRNA, protein:increased expression:cerebral cortex
CTD RGD
PMID:16024175 PMID:21549006
RGD:2311098
NCBI chrNW_004936783:1,210,715...1,218,315
Ensembl chrNW_004936783:1,210,809...1,218,315
G
Il1b
interleukin 1 beta
ISO
protein:increased expression:brain, cerebrospinal fluid mRNA, protein:increased expression:cerebral cortex CTD Direct Evidence: marker/mechanism mRNA, protein:increased expression:brain
RGD CTD
PMID:16024175 PMID:17612572 PMID:19800810 PMID:21549006 PMID:22503903
RGD:1626652 RGD:2311098 RGD:6482651
NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165
G
Il1r1
interleukin 1 receptor type 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004936713:808,761...881,070
Ensembl chrNW_004936713:808,659...881,076
G
Il1rn
interleukin 1 receptor antagonist
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:25665855
NCBI chrNW_004936783:1,447,158...1,466,331
Ensembl chrNW_004936783:1,447,106...1,466,340
G
Il2
interleukin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936662:1,594,953...1,599,625
Ensembl chrNW_004936662:1,594,953...1,599,625
G
Il3
interleukin 3
disease_progression
ISO
protein: increased expression: brain: microdialysis perfusate
RGD
PMID:20717122 PMID:21515263
RGD:5686795 RGD:5686886
NCBI chrNW_004936647:3,102,922...3,104,758
G
Il31ra
interleukin 31 receptor A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936480:11,934,044...11,975,939
Ensembl chrNW_004936480:11,934,063...11,975,910
G
Il5
interleukin 5
treatment
ISO
RGD
PMID:24530657 PMID:24602693
RGD:11522766 RGD:11522770
NCBI chrNW_004936647:2,647,982...2,651,477
Ensembl chrNW_004936647:2,648,241...2,651,430
G
Il6
interleukin 6
ISO
protein:increased expression:cerebrospinal fluid (rat) CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:10027774 PMID:19800810 PMID:21549006 PMID:23159883
RGD:11049549
NCBI chrNW_004936549:7,015,595...7,016,246
G
Il7
interleukin 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936702:110,625...162,957
Ensembl chrNW_004936702:111,211...162,322
G
Il9r
interleukin 9 receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936501:829,236...840,130
Ensembl chrNW_004936501:829,236...840,048
G
Irf1
interferon regulatory factor 1
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:cerebral cortex
CTD RGD
PMID:12503083 PMID:21549006
RGD:2317873
NCBI chrNW_004936647:2,686,247...2,693,633
Ensembl chrNW_004936647:2,686,414...2,693,636
G
Jak2
Janus kinase 2
ISO
RGD
PMID:21596098
RGD:6483023
NCBI chrNW_004936503:111,722...243,627
Ensembl chrNW_004936503:110,963...241,867
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004936522:3,034,364...3,037,632
Ensembl chrNW_004936522:3,035,346...3,036,350
G
Kcnj10
potassium inwardly rectifying channel subfamily J member 10
ISO
RGD
PMID:20861444
RGD:8662901
NCBI chrNW_004936740:555,948...589,219
Ensembl chrNW_004936740:555,998...586,353
G
Kdr
kinase insert domain receptor
ISO
protein:increased expression:cerebral cortex
RGD
PMID:19733172 PMID:21307798
RGD:5684382 RGD:5684402
NCBI chrNW_004936482:17,537,697...17,581,320
Ensembl chrNW_004936482:17,538,864...17,581,002
G
Lep
leptin
ISO
RGD
PMID:21276361
RGD:5128517
NCBI chrNW_004936479:15,394,966...15,411,334
Ensembl chrNW_004936479:15,394,966...15,411,334
G
LOC101956126
heat shock 70 kDa protein 1
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:brain
CTD RGD
PMID:21549006
RGD:5147593
NCBI chrNW_004936727:1,732,323...1,735,128
G
LOC101970551
inhibitor of carbonic anhydrase
ISO
RGD
PMID:22538758
RGD:7244386
NCBI chrNW_004936529:6,856,042...6,895,989
G
LOC101975820
cholesterol side-chain cleavage enzyme, mitochondrial
ISO
mRNA:increased expression:hindbrain
RGD
PMID:16329132
RGD:1599699
NCBI chrNW_004936471:33,367,810...33,380,764
Ensembl chrNW_004936471:33,367,810...33,380,764
G
LOC101976500
haptoglobin
ISO
mRNA:increased expression:liver
RGD
PMID:23172820
RGD:11041806
NCBI chrNW_004936475:21,841,054...21,845,821
G
LOC101977665
tumor necrosis factor ligand superfamily member 12
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936595:831,252...839,783
Ensembl chrNW_004936595:830,466...839,748
G
Lsg1
large 60S subunit nuclear export GTPase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:14499481
NCBI chrNW_004936711:148,748...186,978
Ensembl chrNW_004936711:148,798...186,716
G
Ly86
lymphocyte antigen 86
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004936534:5,848,110...5,908,082
Ensembl chrNW_004936534:5,848,100...5,908,114
G
Mag
myelin associated glycoprotein
susceptibility
ISO
RGD
PMID:17156367
RGD:9685230
NCBI chrNW_004936570:989,743...1,004,820
G
Map1b
microtubule associated protein 1B
ISO
protein:increased expression, increased phosphorylation:brain
RGD
PMID:10906717
RGD:2304029
NCBI chrNW_004936549:4,266,371...4,371,579
Ensembl chrNW_004936549:4,266,351...4,371,644
G
Map1lc3a
microtubule associated protein 1 light chain 3 alpha
ISO
RGD
PMID:24221859
RGD:11558018
NCBI chrNW_004936561:6,104,748...6,106,348
Ensembl chrNW_004936561:6,104,742...6,106,699
G
Map2
microtubule associated protein 2
ISO
protein:decreased expression:cerebral cortex, neuron
RGD
PMID:20568963 PMID:21401443
RGD:6483087 RGD:6483089
NCBI chrNW_004936845:475,406...752,600
Ensembl chrNW_004936845:473,366...545,135
G
Map3k7
mitogen-activated protein kinase kinase kinase 7
treatment
ISO
associated with Subarachnoid Hemorrhage
RGD
PMID:26100626 PMID:27000704 PMID:33414375
RGD:155791672 RGD:155804286 RGD:155882440
NCBI chrNW_004936510:1,772,971...1,836,075
Ensembl chrNW_004936510:1,772,971...1,837,765
G
Mbp
myelin basic protein
ISO
RGD
PMID:18583256
RGD:7349333
NCBI chrNW_004936616:2,082,154...2,159,028
Ensembl chrNW_004936616:2,082,099...2,159,070
G
Mdm2
MDM2 proto-oncogene
ISO
protein:increased expression:brain cortex (rat)
RGD
PMID:15165363
RGD:2317397
NCBI chrNW_004936545:6,709,903...6,732,334
G
Mif
macrophage migration inhibitory factor
ISO
RGD
PMID:15922484
RGD:1641989
NCBI chrNW_004936619:1,207,058...1,208,010
Ensembl chrNW_004936619:1,203,746...1,208,442
G
Mmp9
matrix metallopeptidase 9
treatment
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:16671440 PMID:19631748 PMID:24661104
RGD:13207312 RGD:1582656
NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793
G
Mpo
myeloperoxidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936490:4,809,773...4,819,070
Ensembl chrNW_004936490:4,809,631...4,819,070
G
Mt3
metallothionein 3
treatment
ISO
RGD
PMID:10218634 PMID:10595827 PMID:16314047
RGD:6480628 RGD:9685803 RGD:9685805
NCBI chrNW_004936475:8,864,512...8,866,516
Ensembl chrNW_004936475:8,864,675...8,866,506
G
Myoc
myocilin
ISO
mRNA:increased expression:cerebral cortex (rat)
RGD
PMID:12799138
RGD:7401267
NCBI chrNW_004936481:15,544,733...15,556,813
Ensembl chrNW_004936481:15,544,660...15,556,857
G
Nfe2l2
NFE2 like bZIP transcription factor 2
ISO
protein:increased expression:lung:
RGD
PMID:18787991 PMID:25089700
RGD:11576302 RGD:5134971
NCBI chrNW_004936509:6,589,967...6,621,171
Ensembl chrNW_004936509:6,590,630...6,620,262
G
Ngb
neuroglobin
severity
ISO
RGD
PMID:21915648
RGD:9743963
NCBI chrNW_004936488:6,094,089...6,098,876
Ensembl chrNW_004936488:6,095,016...6,098,543
G
Ngfr
nerve growth factor receptor
treatment
ISO
RGD
PMID:23940017
RGD:10414074
NCBI chrNW_004936490:12,038,500...12,057,257
Ensembl chrNW_004936490:12,035,769...12,057,263
G
Nos2
nitric oxide synthase 2
ISO
RGD
PMID:11526986
RGD:10395358
NCBI chrNW_004936538:4,052,277...4,097,051
Ensembl chrNW_004936538:4,052,448...4,097,051
G
Nox4
NADPH oxidase 4
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:36762617
NCBI chrNW_004936736:230,465...394,859
Ensembl chrNW_004936736:230,476...396,708
G
Nppb
natriuretic peptide B
ISO
CTD Direct Evidence: therapeutic associated with lung diseases;protein:increased expression:serum:
CTD RGD
PMID:19803787 PMID:23837838
RGD:7247620
NCBI chrNW_004936474:683,325...684,662
Ensembl chrNW_004936474:683,325...684,665
G
Npy
neuropeptide Y
ISO
protein:increased expression:adrenal medulla
RGD
PMID:23570732
RGD:10448961
NCBI chrNW_004936478:1,289,437...1,296,819
Ensembl chrNW_004936478:1,290,505...1,296,874
G
Nqo1
NAD(P)H quinone dehydrogenase 1
treatment
ISO
mRNA:increased expression:lung associated with Subarachnoid Hemorrhage
RGD
PMID:18787991 PMID:20864352
RGD:11035222 RGD:5134971
NCBI chrNW_004936475:19,771,384...19,785,034
Ensembl chrNW_004936475:19,769,488...19,785,311
G
Nt5e
5'-nucleotidase ecto
ISO
protein:altered expression:cerebral cortex (rat)
RGD
PMID:21337375
RGD:5134348
NCBI chrNW_004936510:5,797,218...5,846,118
Ensembl chrNW_004936510:5,797,212...5,846,124
G
P2ry1
purinergic receptor P2Y1
ISO
protein:increased expression:brain, astrocyte
RGD
PMID:19115395
RGD:2315811
NCBI chrNW_004936519:865,756...872,466
Ensembl chrNW_004936519:866,208...872,393
G
Palld
palladin, cytoskeletal associated protein
ISO
protein:increased expression:brain, astrocyte
RGD
PMID:12932445
RGD:2325786
NCBI chrNW_004936516:786,358...1,151,910
Ensembl chrNW_004936516:802,484...1,151,801
G
Parp1
poly(ADP-ribose) polymerase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17640816
NCBI chrNW_004936526:3,102,468...3,147,601
Ensembl chrNW_004936526:3,102,039...3,147,642
G
Pawr
pro-apoptotic WT1 regulator
ISO
mRNA,protein:increased expression:brain:
RGD
PMID:11421591
RGD:9835358
NCBI chrNW_004936698:650,225...746,593
Ensembl chrNW_004936698:650,953...747,057
G
Pde4d
phosphodiesterase 4D
ISO
mRNA, protein:alternative form, decreased phosphorylation:brain
RGD
PMID:23057870
RGD:7327147
NCBI chrNW_004936480:8,123,437...9,235,586
Ensembl chrNW_004936480:8,204,701...9,234,865
G
Pdgfa
platelet derived growth factor subunit A
ISO
mRNA:increased expression:cerebral cortex, hippocampus
RGD
PMID:9645955
RGD:11084932
NCBI chrNW_004936754:808,894...828,554
Ensembl chrNW_004936754:808,213...828,613
G
Pdgfb
platelet derived growth factor subunit B
ISO
mRNA:increased expression:cerebral cortex, hippocampus
RGD
PMID:9645955
RGD:11084932
NCBI chrNW_004936492:2,353,840...2,368,573
Ensembl chrNW_004936492:2,353,841...2,368,573
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Pdgfra
platelet derived growth factor receptor alpha
ISO
mRNA:increased expression:cerebral cortex, hippocampus
RGD
PMID:9645955
RGD:11084932
NCBI chrNW_004936482:16,804,129...16,853,539
Ensembl chrNW_004936482:16,807,569...16,853,587
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Pdgfrb
platelet derived growth factor receptor beta
ISO
mRNA:increased expression:cerebral cortex, hippocampus
RGD
PMID:9645955
RGD:11084932
NCBI chrNW_004936504:4,762,251...4,799,789
Ensembl chrNW_004936504:4,762,184...4,799,829
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Pecam1
platelet and endothelial cell adhesion molecule 1
ISO
RGD
PMID:22658532
RGD:6484732
NCBI chrNW_004936541:4,873,459...4,919,787
Ensembl chrNW_004936541:4,873,182...4,937,500
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Pglyrp1
peptidoglycan recognition protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004936706:2,317,137...2,320,993
Ensembl chrNW_004936706:2,315,132...2,320,796
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Pgr
progesterone receptor
ISO
RGD
PMID:23211561
RGD:7248711
NCBI chrNW_004936551:6,498,553...6,573,212
Ensembl chrNW_004936551:6,498,553...6,573,222
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Phb1
prohibitin 1
ISO
protein:increased oxidation:cerebral cortex
RGD
PMID:17518533
RGD:2292409
NCBI chrNW_004936490:12,127,065...12,138,870
Ensembl chrNW_004936490:12,127,065...12,138,870
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Phb2
prohibitin 2
ISO
RGD
PMID:24566151
RGD:12903261
NCBI chrNW_004936709:854,493...859,182
Ensembl chrNW_004936709:854,698...858,851
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Pias1
protein inhibitor of activated STAT 1
ISO
protein:decreased expression:brain, nucleus
RGD
PMID:21545521
RGD:8693413
NCBI chrNW_004936471:27,925,153...28,055,632
Ensembl chrNW_004936471:27,925,153...28,055,632
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Ppara
peroxisome proliferator activated receptor alpha
ISO
agonist more effective in combination with simvastatin
RGD
PMID:18562561
RGD:5508455
NCBI chrNW_004936629:3,672,445...3,725,645
Ensembl chrNW_004936629:3,672,460...3,725,626
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Ppargc1a
PPARG coactivator 1 alpha
treatment
ISO
protein:decreased expression:frontal cortex (rat)
RGD
PMID:22642418 PMID:24345766
RGD:10059630 RGD:6484257
NCBI chrNW_004936477:4,881,230...5,488,208
Ensembl chrNW_004936477:5,199,881...5,488,226
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Ppp3ca
protein phosphatase 3 catalytic subunit alpha
ISO
protein: :hippocampus CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:14499481 PMID:19751097
RGD:6483311
NCBI chrNW_004936520:1,987,989...2,146,473
Ensembl chrNW_004936520:1,987,045...2,146,540
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Prf1
perforin 1
ISO
RGD
PMID:20537642
RGD:6482807
NCBI chrNW_004936521:8,057,874...8,060,695
Ensembl chrNW_004936521:8,057,874...8,060,695
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Ptger3
prostaglandin E receptor 3
ISO
protein:increased expression:striatum, microglia (rat)
RGD
PMID:15234107
RGD:9850280
NCBI chrNW_004936591:1,174,364...1,250,233
Ensembl chrNW_004936591:1,174,069...1,249,410
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Ptgs1
prostaglandin-endoperoxide synthase 1
ISO
protein:increased expression:microglia, macrophage protein:increased expression:microglial cells, macrophage, endothelial cell
RGD
PMID:11565600 PMID:12005397 PMID:19719848
RGD:5688162 RGD:5688239 RGD:5688242
NCBI chrNW_004936487:10,745,465...10,758,812
Ensembl chrNW_004936487:10,745,327...10,758,823
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Ptgs2
prostaglandin-endoperoxide synthase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:12410334 PMID:19719848 PMID:20810888 PMID:21549006 PMID:21866634
RGD:5508191 RGD:5688162
NCBI chrNW_004936481:3,821,564...3,828,086
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Ptprz1
protein tyrosine phosphatase receptor type Z1
ISO
RGD
PMID:12088737
RGD:727637
NCBI chrNW_004936605:3,195,893...3,368,102
Ensembl chrNW_004936605:3,196,548...3,368,175
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Rchy1
ring finger and CHY zinc finger domain containing 1
ISO
protein:increased expression:cerebral cortex
RGD
PMID:21728064
RGD:10045359
NCBI chrNW_004936598:436,559...453,137
Ensembl chrNW_004936598:436,260...453,137
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Rela
RELA proto-oncogene, NF-kB subunit
ISO
protein:increased expression:ileum
RGD
PMID:18288455
RGD:2298787
NCBI chrNW_004936599:3,800,142...3,810,583
Ensembl chrNW_004936599:3,801,636...3,809,813
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Ret
ret proto-oncogene
ISO
mRNA:increased expression:brain
RGD
PMID:18501516
RGD:2324932
NCBI chrNW_004936617:2,927,185...2,980,594
Ensembl chrNW_004936617:2,927,155...2,980,602
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Rhoa
ras homolog family member A
ISO
protein:increased expression:microglial cell, brain
RGD
PMID:17929039
RGD:2298888
NCBI chrNW_004936529:1,000,050...1,045,655
Ensembl chrNW_004936529:999,935...1,045,681
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Robo1
roundabout guidance receptor 1
ISO
mRNA:increased expression:brain protein:increased expression:brain, immune cell
RGD
PMID:16262652 PMID:26550694
RGD:2316136 RGD:243048437
NCBI chrNW_004936505:4,329,428...4,711,310
Ensembl chrNW_004936505:4,330,303...4,709,655
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Robo2
roundabout guidance receptor 2
ISO
mRNA:increased expression:brain
RGD
PMID:16262652
RGD:2316136
NCBI chrNW_004936505:5,544,011...6,747,417
Ensembl chrNW_004936505:5,548,164...6,094,225
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Robo3
roundabout guidance receptor 3
ISO
mRNA:increased expression:brain
RGD
PMID:16262652
RGD:2316136
NCBI chrNW_004936743:1,305,108...1,321,819
Ensembl chrNW_004936743:1,305,341...1,320,702
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Rps27a
ribosomal protein S27a
ISO
mRNA:decreased expression:cerebral cortex, hippocampus
RGD
PMID:17936732
RGD:11041870
NCBI chrNW_004936491:1,630,172...1,632,839
Ensembl chrNW_004936491:1,630,128...1,635,952
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Sele
selectin E
ISO
protein:increased expression:brain
RGD
PMID:19107536
RGD:2313599
NCBI chrNW_004936481:16,915,203...16,921,840
Ensembl chrNW_004936481:16,915,182...16,921,840
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Serpinc1
serpin family C member 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21534203
NCBI chrNW_004936481:13,981,014...13,993,750
Ensembl chrNW_004936481:13,981,019...13,993,634
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Serpinf1
serpin family F member 1
treatment
ISO
human gene in a rat model protein:altered expression:cerebellum (rat)
RGD
PMID:17709187 PMID:20142768
RGD:8612994 RGD:8622925
NCBI chrNW_004936538:7,885,816...7,898,308
Ensembl chrNW_004936538:7,885,475...7,899,113
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Sirt1
sirtuin 1
treatment
ISO
RGD
PMID:17970622
RGD:9497541
NCBI chrNW_004936521:10,296,097...10,316,673
Ensembl chrNW_004936521:10,296,097...10,322,215
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Skp2
S-phase kinase associated protein 2
ISO
protein:increased expression:brain
RGD
PMID:19852587
RGD:2315049
NCBI chrNW_004936518:5,635,856...5,664,057
Ensembl chrNW_004936518:5,637,331...5,664,778
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Slc18a3
solute carrier family 18 member A3
ISO
protein:decreased expression:brain
RGD
PMID:18848922
RGD:5686682
NCBI chrNW_004936728:703,688...706,317
Ensembl chrNW_004936728:704,290...705,885
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Slit1
slit guidance ligand 1
ISO
mRNA:increased expression:brain
RGD
PMID:16262652
RGD:2316136
NCBI chrNW_004936636:2,427,738...2,582,565
Ensembl chrNW_004936636:2,427,736...2,582,578
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Slit2
slit guidance ligand 2
exacerbates
ISO
RGD
PMID:26550694
RGD:243048437
NCBI chrNW_004936477:8,111,212...8,448,567
Ensembl chrNW_004936477:8,109,228...8,446,653
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Slit3
slit guidance ligand 3
ISO
mRNA:increased expression:brain
RGD
PMID:16262652
RGD:2316136
NCBI chrNW_004936622:191,165...756,552
Ensembl chrNW_004936622:565,346...752,299
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Snca
synuclein alpha
ISO
RGD
PMID:14637093 PMID:25089700
RGD:11576302 RGD:6480195
NCBI chrNW_004936685:2,077,017...2,175,298
Ensembl chrNW_004936685:2,076,651...2,175,338
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Sncb
synuclein beta
ISO
RGD
PMID:14637093
RGD:6480195
NCBI chrNW_004936597:878,270...888,346
Ensembl chrNW_004936597:878,286...888,331
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Sncg
synuclein gamma
ISO
RGD
PMID:14637093
RGD:6480195
NCBI chrNW_004936804:16,869...21,684
Ensembl chrNW_004936804:16,614...21,969
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Snw1
SNW domain containing 1
ISO
mRNA, protein:increased expression:cerebral cortex (rat)
RGD
PMID:22965216
RGD:11035237
NCBI chrNW_004936488:6,494,556...6,531,297
Ensembl chrNW_004936488:6,494,562...6,531,600
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Sod1
superoxide dismutase 1
ISO
RGD
PMID:16248885
RGD:1581214
NCBI chrNW_004936500:10,345,154...10,352,873
Ensembl chrNW_004936500:10,345,154...10,352,867
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Sod2
superoxide dismutase 2
ISO
CTD Direct Evidence: therapeutic
RGD CTD
PMID:16248885 PMID:24462953
RGD:1581214
NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781
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Sparc
secreted protein acidic and cysteine rich
ISO
mRNA:increased expression:brain, blood vessel
RGD
PMID:9704602
RGD:2300066
NCBI chrNW_004936515:11,026,156...11,046,812
Ensembl chrNW_004936515:11,025,724...11,046,849
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Sstr2
somatostatin receptor 2
ISO
RGD
PMID:11879809
RGD:2325002
NCBI chrNW_004936655:1,050,835...1,056,609
Ensembl chrNW_004936655:1,051,447...1,052,556
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Sstr3
somatostatin receptor 3
ISO
RGD
PMID:11879809
RGD:2325002
NCBI chrNW_004936492:3,745,455...3,752,330
Ensembl chrNW_004936492:3,748,135...3,751,089
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Sstr4
somatostatin receptor 4
ISO
RGD
PMID:11879809
RGD:2325002
NCBI chrNW_004936620:2,575,880...2,577,761
Ensembl chrNW_004936620:2,576,598...2,577,761
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Stat1
signal transducer and activator of transcription 1
ISO
RGD
PMID:21596098
RGD:6483023
NCBI chrNW_004936506:7,196,860...7,235,854
Ensembl chrNW_004936506:7,196,797...7,233,756
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Stat3
signal transducer and activator of transcription 3
ISO
protein:increased phosphorylation:brain
RGD
PMID:21596098 PMID:22145815 PMID:22827467
RGD:6483023 RGD:6892706 RGD:8694312
NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402
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Strn
striatin
ISO
RGD
PMID:16351572
RGD:2311293
NCBI chrNW_004936663:1,271,549...1,377,609
Ensembl chrNW_004936663:1,271,548...1,377,655
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Tardbp
TAR DNA binding protein
ISO
RGD
PMID:22101322
RGD:5687195
NCBI chrNW_004936474:90,813...103,713
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Th
tyrosine hydroxylase
ISO
protein:decreased activity:striatum (rat)
RGD
PMID:21047500
RGD:5128822
NCBI chrNW_004936794:478,651...486,887
Ensembl chrNW_004936794:478,614...487,061
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Thbd
thrombomodulin
onset
ISO
RGD
PMID:17895610
RGD:5685007
NCBI chrNW_004936620:2,563,900...2,568,117
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Ticam2
toll like receptor adaptor molecule 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004936742:743,191...745,332
Ensembl chrNW_004936742:744,570...745,277
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Timp1
TIMP metallopeptidase inhibitor 1
ISO
mRNA:increased expression:brain, astrocytes
RGD
PMID:10719361
RGD:2290468
NCBI chrNW_004936502:13,345,936...13,350,170
Ensembl chrNW_004936502:13,345,832...13,350,248
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Timp2
TIMP metallopeptidase inhibitor 2
ISO
mRNA:increased expression:brain, neuron, microglial cell
RGD
PMID:10719361
RGD:2290468
NCBI chrNW_004936594:3,232,433...3,244,241
Ensembl chrNW_004936594:3,232,355...3,244,241
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Tjp1
tight junction protein 1
ISO
RGD
PMID:19889224
RGD:2325128
NCBI chrNW_004936483:1,814,870...2,045,802
Ensembl chrNW_004936483:1,814,894...2,030,946
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Tlr1
toll like receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004936482:6,582,430...6,591,128
Ensembl chrNW_004936482:6,582,584...6,584,971
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Tlr2
toll like receptor 2
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:brain
CTD RGD
PMID:18316784 PMID:21549006
RGD:2312713
NCBI chrNW_004936576:522,234...531,660
Ensembl chrNW_004936576:527,434...529,788
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Tlr4
toll like receptor 4
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:brain
CTD RGD
PMID:18316784 PMID:21549006
RGD:2312713
NCBI chrNW_004936487:6,519,140...6,532,018
Ensembl chrNW_004936487:6,518,441...6,533,095
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Tnf
tumor necrosis factor
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:10674461 PMID:19800810 PMID:21549006
RGD:13825262
NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
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Tnfrsf13b
TNF receptor superfamily member 13B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936741:626,814...637,317
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Tnfrsf13c
TNF receptor superfamily member 13C
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936492:98,878...101,920
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Tnfrsf14
TNF receptor superfamily member 14
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936737:1,008,228...1,013,575
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Tnfrsf1a
TNF receptor superfamily member 1A
ISO
protein:increased expression:brain CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:17074049 PMID:21549006
RGD:1624183
NCBI chrNW_004936709:1,407,327...1,421,448
Ensembl chrNW_004936709:1,407,278...1,421,921
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Tnfsf10
TNF superfamily member 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936593:212,642...230,645
Ensembl chrNW_004936593:212,532...230,651
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Traf4
TNF receptor associated factor 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004936538:4,952,627...4,958,696
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Trpm2
transient receptor potential cation channel subfamily M member 2
ISO
mRNA, protein:increased expression:cerebral cortex, hippocampus
RGD
PMID:20309649
RGD:9999437
NCBI chrNW_004936500:21,960...76,895
Ensembl chrNW_004936500:21,942...77,260
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Uba52
ubiquitin A-52 residue ribosomal protein fusion product 1
ISO
mRNA:decreased expression:cerebral cortex, hippocampus (rat)
RGD
PMID:17936732
RGD:11041870
NCBI chrNW_004936596:2,706,990...2,709,957
Ensembl chrNW_004936596:2,706,994...2,719,846
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Ucp2
uncoupling protein 2
ISO
CTD Direct Evidence: therapeutic
RGD CTD
PMID:12858170
RGD:7204436
NCBI chrNW_004936498:3,059,700...3,066,112
Ensembl chrNW_004936498:3,059,297...3,066,197
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Vegfa
vascular endothelial growth factor A
ISO
CTD Direct Evidence: therapeutic
CTD RGD
PMID:12230324 PMID:18065154
RGD:1580574
NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673
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Vegfb
vascular endothelial growth factor B
ISO
mRNA, protein:increased expression:brain
RGD
PMID:12230324
RGD:1580574
NCBI chrNW_004936599:4,963,161...4,966,258
Ensembl chrNW_004936599:4,962,222...4,966,264
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Vim
vimentin
ISO
protein:increased expression:brain
RGD
PMID:15527750 PMID:19728994
RGD:6480519 RGD:6480527
NCBI chrNW_004936520:10,051,692...10,059,324
Ensembl chrNW_004936520:10,052,012...10,059,182
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Xdh
xanthine dehydrogenase
treatment
ISO
RGD
PMID:26528358
RGD:13208950
NCBI chrNW_004936493:1,762,814...1,824,501
Ensembl chrNW_004936493:1,762,869...1,823,238
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Apoe
apolipoprotein E
susceptibility
ISO
DNA:polymorphism:exon:
RGD
PMID:9214529
RGD:7495763
NCBI chrNW_004936706:1,512,438...1,516,805
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Tardbp
TAR DNA binding protein
ISO
protein:increased expression:brain
RGD
PMID:20720505
RGD:5687179
NCBI chrNW_004936474:90,813...103,713
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Becn1
beclin 1
ISO
protein:increased expression:neuron
RGD
PMID:16004578
RGD:6483315
NCBI chrNW_004936490:17,518,100...17,531,126
Ensembl chrNW_004936490:17,517,751...17,531,151
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Gfap
glial fibrillary acidic protein
ISO
RGD
PMID:8833197
RGD:6480531
NCBI chrNW_004936541:1,265,915...1,275,232
Ensembl chrNW_004936541:1,265,436...1,275,296
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Got1
glutamic-oxaloacetic transaminase 1
ISO
human protein in a rat model
RGD
PMID:17014847
RGD:13504858
NCBI chrNW_004936636:617,376...640,424
Ensembl chrNW_004936636:617,356...640,932
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Igf1
insulin like growth factor 1
ISO
protein:decreased expression:serum:
RGD
PMID:12002507
RGD:8548865
NCBI chrNW_004936492:11,709,623...11,784,028
Ensembl chrNW_004936492:11,709,222...11,778,351
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Igfbp3
insulin like growth factor binding protein 3
ISO
protein:decreased expression:serum:
RGD
PMID:12002507
RGD:8548865
NCBI chrNW_004936478:20,511,490...20,518,251
Ensembl chrNW_004936478:20,510,137...20,518,306
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Vim
vimentin
ISO
RGD
PMID:8833197
RGD:6480531
NCBI chrNW_004936520:10,051,692...10,059,324
Ensembl chrNW_004936520:10,052,012...10,059,182
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Aldh3a1
aldehyde dehydrogenase 3 family member A1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28038895
NCBI chrNW_004936881:71,047...77,543
Ensembl chrNW_004936881:70,951...77,839
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Tp63
tumor protein p63
ISO
RGD
PMID:12167247
RGD:11568649
NCBI chrNW_004936578:492,267...705,282
Ensembl chrNW_004936578:491,507...705,729
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Ifng
interferon gamma
ISO
mRNA,protein:increased expression:corneal
RGD
PMID:15832292
RGD:8157597
NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452
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Bmp4
bone morphogenetic protein 4
ISO
mRNA:increased expression:superior cervical ganglion
RGD
PMID:16420416
RGD:2289006
NCBI chrNW_004936697:1,054,237...1,061,468
Ensembl chrNW_004936697:1,056,636...1,061,468
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Cx3cl1
C-X3-C motif chemokine ligand 1
ISO
RGD
PMID:15153618
RGD:4891994
NCBI chrNW_004936475:9,443,851...9,454,715
Ensembl chrNW_004936475:9,443,733...9,455,062
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Il10
interleukin 10
treatment
ISO
RGD
PMID:22553604
RGD:7364851
NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502
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Il1b
interleukin 1 beta
ISO
protein:increased expression:retina
RGD
PMID:9618720
RGD:7794723
NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165
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Pparg
peroxisome proliferator activated receptor gamma
ISO
protein:increased expression:cornea, neutrophil, macrophage (rat)
RGD
PMID:24194635
RGD:8552904
NCBI chrNW_004936602:1,230,907...1,368,588
Ensembl chrNW_004936602:1,230,907...1,304,743
G
Pparg
peroxisome proliferator activated receptor gamma
treatment
ISO
RGD
PMID:18658087
RGD:8552893
NCBI chrNW_004936602:1,230,907...1,368,588
Ensembl chrNW_004936602:1,230,907...1,304,743
G
Adcyap1
adenylate cyclase activating polypeptide 1
ISO
mRNA:increased expression:facial VII nucleus
RGD
PMID:19427307
RGD:2325258
NCBI chrNW_004936672:3,461,387...3,468,053
Ensembl chrNW_004936672:3,460,383...3,468,255
G
Atf2
activating transcription factor 2
ISO
RGD
PMID:9813301
RGD:10047413
NCBI chrNW_004936509:4,729,984...4,826,367
Ensembl chrNW_004936509:4,732,930...4,826,443
G
Ccr3
C-C motif chemokine receptor 3
ISO
RGD
PMID:19922414
RGD:6892922
NCBI chrNW_004936596:223,660...224,739
Ensembl chrNW_004936596:223,660...224,739
G
Cd59
CD59 molecule (CD59 blood group)
ISO
mRNA, protein:increased expression:facial VII nucleus
RGD
PMID:9846834
RGD:1600495
NCBI chrNW_004936533:4,242,589...4,263,136
G
Clu
clusterin
ISO
protein:increased expression:neuron,astrocyte
RGD
PMID:10800205
RGD:408418725
NCBI chrNW_004936675:499,745...513,515
Ensembl chrNW_004936675:499,199...513,836
G
Csf1
colony stimulating factor 1
ISO
protein:increased expression:facial VII nerve, microglial cell
RGD
PMID:20831658
RGD:5131509
NCBI chrNW_004936704:1,372,137...1,393,355
Ensembl chrNW_004936704:1,378,103...1,393,542
G
Ctss
cathepsin S
ISO
RGD
PMID:17539023
RGD:5686912
NCBI chrNW_004936580:963,176...991,732
Ensembl chrNW_004936580:963,153...991,442
G
Gfra1
GDNF family receptor alpha 1
ISO
mRNA:increased expression:facial VII nucleus
RGD
PMID:9582449
RGD:6218984
NCBI chrNW_004936486:6,066,108...6,262,055
Ensembl chrNW_004936486:6,071,023...6,262,165
G
Hgf
hepatocyte growth factor
treatment
ISO
RGD
PMID:21562589
RGD:8548634
NCBI chrNW_004936734:354,798...428,356
Ensembl chrNW_004936734:356,115...428,779
G
Mt3
metallothionein 3
treatment
ISO
RGD
PMID:14625437
RGD:9685806
NCBI chrNW_004936475:8,864,512...8,866,516
Ensembl chrNW_004936475:8,864,675...8,866,506
G
Ndufa5
NADH:ubiquinone oxidoreductase subunit A5
ISO
mRNA:increased expression:skeletal muscle
RGD
PMID:8875451
RGD:2302319
NCBI chrNW_004936605:1,915,246...1,928,853
Ensembl chrNW_004936605:1,915,031...1,928,732
G
Ret
ret proto-oncogene
ISO
mRNA:increased expression:facial VII nucleus
RGD
PMID:9582449
RGD:6218984
NCBI chrNW_004936617:2,927,185...2,980,594
Ensembl chrNW_004936617:2,927,155...2,980,602
G
Acvr1b
activin A receptor type 1B
ISO
RGD
PMID:9013782
RGD:151665480
NCBI chrNW_004936512:9,407,578...9,449,611
Ensembl chrNW_004936512:9,407,581...9,449,632
G
Adamts1
ADAM metallopeptidase with thrombospondin type 1 motif 1
ISO
mRNA:increased expression:hypoglossal nerve
RGD
PMID:11311987
RGD:5037239
NCBI chrNW_004936640:959,405...967,305
Ensembl chrNW_004936640:959,417...968,842
G
Aif1
allograft inflammatory factor 1
ISO
RGD
PMID:9698327
RGD:704401
NCBI chrNW_004936727:1,907,493...1,909,350
Ensembl chrNW_004936727:1,907,505...1,909,338
G
Csnk2b
casein kinase 2 beta
ISO
RGD
PMID:11068334
RGD:11565824
NCBI chrNW_004936727:1,857,596...1,862,551
Ensembl chrNW_004936727:1,857,596...1,862,002
G
Fgfr1
fibroblast growth factor receptor 1
ISO
RGD
PMID:9183688
RGD:8655640
NCBI chrNW_004936710:1,760,365...1,815,269
Ensembl chrNW_004936710:1,760,089...1,815,508
G
Gfra1
GDNF family receptor alpha 1
ISO
mRNA:increased expression:hypoglossal XII nerve
RGD
PMID:10407179
RGD:6218979
NCBI chrNW_004936486:6,066,108...6,262,055
Ensembl chrNW_004936486:6,071,023...6,262,165
G
Il1r1
interleukin 1 receptor type 1
ISO
mRNA:increased expression:hypoglossal nerve
RGD
PMID:11311987
RGD:5037239
NCBI chrNW_004936713:808,761...881,070
Ensembl chrNW_004936713:808,659...881,076
G
Mcam
melanoma cell adhesion molecule
ISO
RGD
PMID:10076889
RGD:7364787
NCBI chrNW_004936542:4,235,914...4,244,981
Ensembl chrNW_004936542:4,237,010...4,244,462
G
Mme
membrane metalloendopeptidase
ISO
RGD
PMID:8201016
RGD:13801045
NCBI chrNW_004936519:2,513,896...2,595,896
Ensembl chrNW_004936519:2,513,704...2,595,971
G
Prkaca
protein kinase cAMP-activated catalytic subunit alpha
ISO
RGD
PMID:7769990
RGD:7327191
NCBI chrNW_004936659:2,750,015...2,765,914
Ensembl chrNW_004936659:2,750,537...2,765,753
G
Prkacb
protein kinase cAMP-activated catalytic subunit beta
ISO
RGD
PMID:7769990
RGD:7327191
NCBI chrNW_004936608:1,353,905...1,464,636
Ensembl chrNW_004936608:1,353,897...1,464,636
G
Ret
ret proto-oncogene
ISO
mRNA:increased expression:hypoglossal XII nerve
RGD
PMID:10407179
RGD:6218979
NCBI chrNW_004936617:2,927,185...2,980,594
Ensembl chrNW_004936617:2,927,155...2,980,602
G
Smad1
SMAD family member 1
ISO
mRNA:increased expression:hypoglossal nucleus
RGD
PMID:17166487
RGD:1643227
NCBI chrNW_004936535:3,582,512...3,626,312
Ensembl chrNW_004936535:3,582,489...3,657,063
G
Smad2
SMAD family member 2
ISO
mRNA:increased expression:hypoglossal nucleus
RGD
PMID:17166487
RGD:1643227
NCBI chrNW_004936497:14,723,199...14,812,160
Ensembl chrNW_004936497:14,723,199...14,801,697
G
Smad3
SMAD family member 3
ISO
mRNA:increased expression:hypoglossal nucleus
RGD
PMID:17166487
RGD:1643227
NCBI chrNW_004936471:27,080,662...27,185,861
Ensembl chrNW_004936471:27,080,575...27,189,793
G
Smad4
SMAD family member 4
ISO
mRNA:increased expression:hypoglossal nucleus
RGD
PMID:17166487
RGD:1643227
NCBI chrNW_004936497:12,242,869...12,278,012
Ensembl chrNW_004936497:12,249,140...12,278,123
G
Smad7
SMAD family member 7
ISO
mRNA:increased expression:hypoglossal nucleus
RGD
PMID:17166487
RGD:1643227
NCBI chrNW_004936497:13,894,586...13,921,978
Ensembl chrNW_004936497:13,894,580...13,922,065
G
Smad9
SMAD family member 9
ISO
mRNA:decreased expression:hypoglossal nucleus
RGD
PMID:17166487
RGD:1643227
NCBI chrNW_004936472:30,980,850...31,050,138
Ensembl chrNW_004936472:30,980,928...31,049,618
G
Txnrd1
thioredoxin reductase 1
ISO
mRNA, protein:increased expression:neuron
RGD
PMID:19833109
RGD:5133729
NCBI chrNW_004936492:10,185,096...10,244,466
Ensembl chrNW_004936492:10,187,206...10,225,989
G
Gp6
glycoprotein VI platelet
exacerbates
ISO
RGD
PMID:21258336
RGD:401824683
NCBI chrNW_004936886:295,950...310,614
Ensembl chrNW_004936886:296,025...310,614
G
Mdm2
MDM2 proto-oncogene
treatment
ISO
RGD
PMID:34334113
RGD:155882538
NCBI chrNW_004936545:6,709,903...6,732,334
G
Zeb2
zinc finger E-box binding homeobox 2
treatment
ISO
protein:increased expression:brain (rat)
RGD
PMID:34334113
RGD:155882538
NCBI chrNW_004936469:32,240,730...32,372,413
Ensembl chrNW_004936469:32,240,835...32,371,267
G
Cited2
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2
ISO
mRNA:decreased expression:bone
RGD
PMID:19607804
RGD:5147852
NCBI chrNW_004936560:6,353,901...6,356,749
Ensembl chrNW_004936560:6,354,338...6,356,735
G
Ihh
Indian hedgehog signaling molecule
ISO
RGD
PMID:23992905
RGD:12911207
NCBI chrNW_004936569:1,474,693...1,480,562
Ensembl chrNW_004936569:1,474,665...1,480,568
G
Ntrk2
neurotrophic receptor tyrosine kinase 2
ISO
mRNA:increased expression:motor neuron
RGD
PMID:21456016
RGD:5684341
NCBI chrNW_004936680:267,850...621,467
Ensembl chrNW_004936680:267,596...615,928
G
Adcy10
adenylate cyclase 10
ISO
protein:decreased expression:retina
RGD
PMID:22649251
RGD:329347828
NCBI chrNW_004936481:18,274,158...18,330,136
Ensembl chrNW_004936481:18,274,154...18,330,173
G
Adnp
activity dependent neuroprotector homeobox
ISO
RGD
PMID:18414890
RGD:2312783
NCBI chrNW_004936514:3,855,113...3,883,036
Ensembl chrNW_004936514:3,855,672...3,885,718
G
Amigo3
adhesion molecule with Ig like domain 3
treatment
ISO
RGD
PMID:23613963
RGD:14390159
NCBI chrNW_004936529:1,331,610...1,335,058
Ensembl chrNW_004936529:1,332,874...1,334,403
G
Aqp4
aquaporin 4
ISO
RGD
PMID:20216911
RGD:2326035
NCBI chrNW_004936550:5,931,201...5,943,999
Ensembl chrNW_004936550:5,931,194...5,941,354
G
Aqp9
aquaporin 9
ISO
RGD
PMID:20216911
RGD:2326035
NCBI chrNW_004936471:19,321,366...19,361,227
Ensembl chrNW_004936471:19,321,426...19,362,146
G
Arg2
arginase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30618589
NCBI chrNW_004936495:11,004,296...11,045,467
Ensembl chrNW_004936495:11,004,176...11,045,472
G
Atf2
activating transcription factor 2
ISO
RGD
PMID:10366744
RGD:10047417
NCBI chrNW_004936509:4,729,984...4,826,367
Ensembl chrNW_004936509:4,732,930...4,826,443
G
Bax
BCL2 associated X, apoptosis regulator
ISO
mRNA:increased expression:optic nerve, retina
RGD
PMID:24357921
RGD:10054098
NCBI chrNW_004936664:2,968,103...2,973,652
Ensembl chrNW_004936664:2,967,865...2,973,820
G
Bcl2
BCL2 apoptosis regulator
ISO
mRNA:decreased expression:optic nerve, retina
RGD
PMID:24357921
RGD:10054098
NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921
G
Bdnf
brain derived neurotrophic factor
treatment
ISO
RGD
PMID:9520478 PMID:11050383 PMID:15140649
RGD:8655584 RGD:8655586 RGD:8655637
NCBI chrNW_004936540:5,530,081...5,582,765
Ensembl chrNW_004936540:5,529,942...5,585,014
G
C3
complement C3
ISO
mRNA:increased expression:optic nerve
RGD
PMID:14577867
RGD:5129542
NCBI chrNW_004936588:3,985,732...4,023,221
G
Cdk2
cyclin dependent kinase 2
ISO
mRNA:increased expression:retina
RGD
PMID:16723461
RGD:2293567
NCBI chrNW_004936646:379,849...385,648
Ensembl chrNW_004936646:379,842...385,877
G
Cfl1
cofilin 1
treatment
ISO
RGD
PMID:27443501
RGD:11568693
NCBI chrNW_004936599:3,678,724...3,682,314
Ensembl chrNW_004936599:3,677,804...3,682,307
G
Clu
clusterin
ISO
RGD
PMID:14577867
RGD:5129542
NCBI chrNW_004936675:499,745...513,515
Ensembl chrNW_004936675:499,199...513,836
G
Csf1r
colony stimulating factor 1 receptor
ISO
mRNA:increased expression:retina (rat)
RGD
PMID:20187850
RGD:151665810
NCBI chrNW_004936504:4,898,947...4,927,195
Ensembl chrNW_004936504:4,898,945...4,928,923
G
Csf3
colony stimulating factor 3
treatment
ISO
RGD
PMID:20144610
RGD:11039471
NCBI chrNW_004936490:15,142,526...15,146,375
Ensembl chrNW_004936490:15,142,808...15,144,487
G
Edn1
endothelin 1
ISO
protein:increased expression:retina
RGD
PMID:18600494
RGD:4892579
NCBI chrNW_004936534:885,489...892,292
Ensembl chrNW_004936534:885,287...891,772
G
Ednra
endothelin receptor type A
ISO
mRNA:increased expression:retina
RGD
PMID:18600494
RGD:4892579
NCBI chrNW_004936535:1,950,117...2,005,786
Ensembl chrNW_004936535:1,949,941...2,005,910
G
Ednrb
endothelin receptor type B
ISO
mRNA:increased expression:retina
RGD
PMID:18600494
RGD:4892579
NCBI chrNW_004936511:3,446,864...3,478,434
Ensembl chrNW_004936511:3,446,839...3,478,434
G
Ep300
E1A binding protein p300
ISO
protein:decreased expression:retinal ganglion cell layer (rat) human gene in rat model
RGD
PMID:21705428
RGD:7349392
NCBI chrNW_004936492:696,982...778,132
Ensembl chrNW_004936492:696,960...778,138
G
Fto
FTO alpha-ketoglutarate dependent dioxygenase
ISO
mRNA:increased expression:retina
RGD
PMID:33664770
RGD:329951020
NCBI chrNW_004936475:6,321,725...6,689,410
Ensembl chrNW_004936475:6,321,711...6,689,588
G
Gdnf
glial cell derived neurotrophic factor
ISO
RGD
PMID:15144875
RGD:6218970
NCBI chrNW_004936518:4,291,391...4,310,752
Ensembl chrNW_004936518:4,288,154...4,310,753
G
Gfra1
GDNF family receptor alpha 1
ISO
RGD
PMID:15144875
RGD:6218970
NCBI chrNW_004936486:6,066,108...6,262,055
Ensembl chrNW_004936486:6,071,023...6,262,165
G
Gfra2
GDNF family receptor alpha 2
ISO
RGD
PMID:15144875
RGD:6218970
NCBI chrNW_004936555:5,573,765...5,653,881
Ensembl chrNW_004936555:5,573,720...5,653,509
G
Hgf
hepatocyte growth factor
treatment
ISO
RGD
PMID:21443522
RGD:8548549
NCBI chrNW_004936734:354,798...428,356
Ensembl chrNW_004936734:356,115...428,779
G
Igf1r
insulin like growth factor 1 receptor
ISO
protein:increased expression:retina: protein: altered activity: eye
RGD
PMID:19484445 PMID:23648097
RGD:10046025 RGD:5686431
NCBI chrNW_004936483:4,563,995...4,860,231
Ensembl chrNW_004936483:4,564,512...4,852,925
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
ISO
RGD
PMID:10366744
RGD:10047417
NCBI chrNW_004936522:3,034,364...3,037,632
Ensembl chrNW_004936522:3,035,346...3,036,350
G
Kcnj10
potassium inwardly rectifying channel subfamily J member 10
ISO
RGD
PMID:20216911
RGD:2326035
NCBI chrNW_004936740:555,948...589,219
Ensembl chrNW_004936740:555,998...586,353
G
Myrf
myelin regulatory factor
ISO
mRNA:decreased expression: oligodendrocyte
RGD
PMID:29915135
RGD:213230153
NCBI chrNW_004936581:1,335,969...1,367,104
Ensembl chrNW_004936581:1,338,762...1,367,104
G
Nampt
nicotinamide phosphoribosyltransferase
treatment
ISO
RGD
PMID:28032230
RGD:13781885
NCBI chrNW_004936479:17,682,070...17,716,713
Ensembl chrNW_004936479:17,682,201...17,716,661
G
Ncam1
neural cell adhesion molecule 1
ISO
RGD
PMID:18757519
RGD:2326023
NCBI chrNW_004936612:1,262,557...1,556,281
Ensembl chrNW_004936612:1,262,544...1,556,016
G
Nefm
neurofilament medium chain
ISO
RGD
PMID:8501527
RGD:9743936
NCBI chrNW_004936757:1,662,905...1,668,707
Ensembl chrNW_004936757:1,663,399...1,668,075
G
Neo1
neogenin 1
ISO
protein:increased expression:retina
RGD
PMID:21887516
RGD:9850142
NCBI chrNW_004936471:32,345,578...32,517,245
Ensembl chrNW_004936471:32,292,745...32,516,624
G
Ngf
nerve growth factor
ISO
protein:increased expression:retina
RGD
PMID:28067793
RGD:402463954
NCBI chrNW_004936627:635,784...641,290
Ensembl chrNW_004936627:635,788...645,364
G
Ngfr
nerve growth factor receptor
ISO
RGD
PMID:20943663
RGD:5508695
NCBI chrNW_004936490:12,038,500...12,057,257
Ensembl chrNW_004936490:12,035,769...12,057,263
G
Ntrk1
neurotrophic receptor tyrosine kinase 1
ISO
RGD
PMID:20943663
RGD:5508695
NCBI chrNW_004936580:6,002,168...6,021,690
Ensembl chrNW_004936580:6,002,120...6,021,709
G
Ntrk2
neurotrophic receptor tyrosine kinase 2
treatment
ISO
RGD
PMID:20357199 PMID:34245756
RGD:5684908 RGD:597015764
NCBI chrNW_004936680:267,850...621,467
Ensembl chrNW_004936680:267,596...615,928
G
Pawr
pro-apoptotic WT1 regulator
ISO
mRNA:increased expression:retina:
RGD
PMID:12836167
RGD:1299297
NCBI chrNW_004936698:650,225...746,593
Ensembl chrNW_004936698:650,953...747,057
G
Pax6
paired box 6
ISO
protein:increased expression:retina (rat)
RGD
PMID:23297010
RGD:8552379
NCBI chrNW_004936533:5,952,529...5,980,889
Ensembl chrNW_004936533:5,957,971...5,982,075
G
Pdgfb
platelet derived growth factor subunit B
ISO
protein:decreased expression:nerve fiber:
RGD
PMID:9893812
RGD:10449496
NCBI chrNW_004936492:2,353,840...2,368,573
Ensembl chrNW_004936492:2,353,841...2,368,573
G
Pecam1
platelet and endothelial cell adhesion molecule 1
ISO
protein:increased expression:optic nerve (rat)
RGD
PMID:22336118
RGD:6767293
NCBI chrNW_004936541:4,873,459...4,919,787
Ensembl chrNW_004936541:4,873,182...4,937,500
G
Plau
plasminogen activator, urokinase
ISO
mRNA:increased expression:optic nerve (rat)
RGD
PMID:20798533
RGD:6483802
NCBI chrNW_004936521:5,238,128...5,243,829
Ensembl chrNW_004936521:5,238,093...5,243,877
G
Ptpn5
protein tyrosine phosphatase non-receptor type 5
ISO
protein:increased expression:retina (rat)
RGD
PMID:15555919
RGD:9835027
NCBI chrNW_004936528:523,884...586,306
Ensembl chrNW_004936528:525,769...586,327
G
Rhoa
ras homolog family member A
ISO
protein:increased expression, altered localization:retina
RGD
PMID:17534117
RGD:1642826
NCBI chrNW_004936529:1,000,050...1,045,655
Ensembl chrNW_004936529:999,935...1,045,681
G
Snw1
SNW domain containing 1
ISO
protein:increased expression:retina (rat)
RGD
PMID:25074585
RGD:11035254
NCBI chrNW_004936488:6,494,556...6,531,297
Ensembl chrNW_004936488:6,494,562...6,531,600
G
Tlr2
toll like receptor 2
treatment
ISO
RGD
PMID:19661221
RGD:597538516
NCBI chrNW_004936576:522,234...531,660
Ensembl chrNW_004936576:527,434...529,788
G
Tlr4
toll like receptor 4
ISO
protein:increased expression:optic nerve
RGD
PMID:23103505
RGD:7794777
NCBI chrNW_004936487:6,519,140...6,532,018
Ensembl chrNW_004936487:6,518,441...6,533,095
G
Tnfrsf1a
TNF receptor superfamily member 1A
ISO
RGD
PMID:14697498 PMID:18552980
RGD:7794683 RGD:8661743
NCBI chrNW_004936709:1,407,327...1,421,448
Ensembl chrNW_004936709:1,407,278...1,421,921
G
Tradd
TNFRSF1A associated via death domain
ISO
protein:increased expression: retina
RGD
PMID:18552980
RGD:7794683
NCBI chrNW_004936475:17,628,297...17,634,919
Ensembl chrNW_004936475:17,628,803...17,630,856
G
Neo1
neogenin 1
ISO
protein:increased expression:retina
RGD
PMID:21887516
RGD:9850142
NCBI chrNW_004936471:32,345,578...32,517,245
Ensembl chrNW_004936471:32,292,745...32,516,624
G
Rgma
repulsive guidance molecule BMP co-receptor a
ISO
protein:increased expression:retina
RGD
PMID:21887516
RGD:9850142
NCBI chrNW_004936483:9,753,112...9,792,817
Ensembl chrNW_004936483:9,766,275...9,793,001
G
Fgfr1
fibroblast growth factor receptor 1
ISO
mRNA,protein:increased expression:astrocyte,macrophage,neutrophil:
RGD
PMID:11168551
RGD:10402049
NCBI chrNW_004936710:1,760,365...1,815,269
Ensembl chrNW_004936710:1,760,089...1,815,508
G
Gfap
glial fibrillary acidic protein
ISO
RGD
PMID:10225952
RGD:6480471
NCBI chrNW_004936541:1,265,915...1,275,232
Ensembl chrNW_004936541:1,265,436...1,275,296
G
Pdgfb
platelet derived growth factor subunit B
ISO
protein:increased expression:neuron:
RGD
PMID:7526956
RGD:10449485
NCBI chrNW_004936492:2,353,840...2,368,573
Ensembl chrNW_004936492:2,353,841...2,368,573
G
Vim
vimentin
ISO
RGD
PMID:10225952
RGD:6480471
NCBI chrNW_004936520:10,051,692...10,059,324
Ensembl chrNW_004936520:10,052,012...10,059,182
G
Trh
thyrotropin releasing hormone
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:8690305
NCBI chrNW_004936602:623,542...626,337
Ensembl chrNW_004936602:623,535...626,445
G
Bmp4
bone morphogenetic protein 4
treatment
ISO
RGD
PMID:16332232
RGD:8699514
NCBI chrNW_004936697:1,054,237...1,061,468
Ensembl chrNW_004936697:1,056,636...1,061,468
G
Igf1
insulin like growth factor 1
ISO
protein:decreased expression:serum:
RGD
PMID:12002507
RGD:8548865
NCBI chrNW_004936492:11,709,623...11,784,028
Ensembl chrNW_004936492:11,709,222...11,778,351
G
Plat
plasminogen activator, tissue type
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:1899364
NCBI chrNW_004936785:476,200...503,371
Ensembl chrNW_004936785:476,078...503,321
G
Adam10
ADAM metallopeptidase domain 10
ISO
RGD
PMID:22489706
RGD:13703033
NCBI chrNW_004936471:19,760,709...19,911,759
Ensembl chrNW_004936471:19,758,118...19,911,759
G
Ahr
aryl hydrocarbon receptor
ISO
protein:increased expression:T cell, neuron, brain cortex, hippocampus
RGD
PMID:27506546
RGD:405878081
NCBI chrNW_004936546:3,737,908...3,783,492
Ensembl chrNW_004936546:3,737,851...3,783,588
G
App
amyloid beta precursor protein
treatment
ISO
RGD
PMID:29320530
RGD:13782048
NCBI chrNW_004936640:1,549,977...1,787,436
Ensembl chrNW_004936640:1,550,167...1,787,286
G
Bad
BCL2 associated agonist of cell death
treatment
ISO
RGD
PMID:24582457
RGD:13782254
NCBI chrNW_004936599:4,924,349...4,933,683
Ensembl chrNW_004936599:4,924,789...4,933,368
G
Bdnf
brain derived neurotrophic factor
ISO
mRNA:increased expression:CA3 field of hippocampus, dentate gyrus
RGD
PMID:10925157
RGD:596936229
NCBI chrNW_004936540:5,530,081...5,582,765
Ensembl chrNW_004936540:5,529,942...5,585,014
G
Bid
BH3 interacting domain death agonist
disease_progression severity
ISO
RGD
PMID:12172380 PMID:15307896
RGD:5509821 RGD:632018
NCBI chrNW_004936807:708,340...750,127
Ensembl chrNW_004936807:708,276...750,093
G
Capn1
calpain 1
severity
ISO
protein:increased expression:cytosol, plasma membrane
RGD
PMID:9469158 PMID:15307896
RGD:13792664 RGD:5509821
NCBI chrNW_004936599:4,178,963...4,201,037
Ensembl chrNW_004936599:4,178,901...4,201,052
G
Capn2
calpain 2
severity
ISO
RGD
PMID:9469158 PMID:15307896
RGD:13792664 RGD:5509821
NCBI chrNW_004936526:879,765...932,682
Ensembl chrNW_004936526:879,765...932,682
G
Casp3
caspase 3
severity
ISO
protein:increased expression:cerebral cortex
RGD
PMID:15307896 PMID:27614125
RGD:329961568 RGD:5509821
NCBI chrNW_004936554:4,571,072...4,593,765
G
Casp8
caspase 8
severity disease_progression
ISO
RGD
PMID:12172380 PMID:15307896
RGD:5509821 RGD:632018
NCBI chrNW_004936726:554,627...596,334
Ensembl chrNW_004936726:554,758...595,922
G
Casp9
caspase 9
severity disease_progression
ISO
RGD
PMID:12172380 PMID:15307896
RGD:5509821 RGD:632018
NCBI chrNW_004936474:3,178,097...3,196,130
G
Ccng1
cyclin G1
treatment
ISO
RGD
PMID:18612315 PMID:24398934
RGD:151356934 RGD:151356935
NCBI chrNW_004936515:614,287...621,213
Ensembl chrNW_004936515:614,290...619,963
G
Cd8a
CD8 subunit alpha
ISO
mRNA:increased expression:brain (mouse)
RGD
PMID:31383034
RGD:124715446
NCBI chrNW_004936712:885,301...891,247
Ensembl chrNW_004936712:885,458...890,852
G
Cit
citron rho-interacting serine/threonine kinase
ISO
mRNA:decreased expression:cerebral cortex��(rat)
RGD
PMID:12503083
RGD:2317873
NCBI chrNW_004936668:991,043...1,146,578
Ensembl chrNW_004936668:991,036...1,146,294
G
Ctnnb1
catenin beta 1
treatment
ISO
RGD
PMID:26296359
RGD:597538582
NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293
G
Cxcl10
C-X-C motif chemokine ligand 10
treatment
ISO
RGD
PMID:26435412
RGD:27095897
NCBI chrNW_004936676:60,869...63,028
Ensembl chrNW_004936676:60,621...63,106
G
Cxcl12
C-X-C motif chemokine ligand 12
ISO
protein:increased expression:cerebral cortex
RGD
PMID:27614125
RGD:329961568
NCBI chrNW_004936617:4,224,131...4,239,080
Ensembl chrNW_004936617:4,224,131...4,238,796
G
Drd1
dopamine receptor D1
treatment
ISO
RGD
PMID:24047867
RGD:13506948
NCBI chrNW_004936609:790,647...795,187
Ensembl chrNW_004936609:792,276...793,613
G
Drd2
dopamine receptor D2
treatment
ISO
RGD
PMID:24047867
RGD:13506948
NCBI chrNW_004936612:1,094,686...1,154,149
Ensembl chrNW_004936612:1,094,680...1,154,798
G
Fto
FTO alpha-ketoglutarate dependent dioxygenase
ISO
mRNA:decreased expression:cerebral cortex
RGD
PMID:31992337
RGD:329901857
NCBI chrNW_004936475:6,321,725...6,689,410
Ensembl chrNW_004936475:6,321,711...6,689,588
G
Fubp1
far upstream element binding protein 1
ISO
RGD
PMID:23797733
RGD:13673879
NCBI chrNW_004936571:4,729,135...4,760,943
Ensembl chrNW_004936571:4,732,581...4,760,942
G
Gnal
G protein subunit alpha L
ISO
RGD
PMID:29215295
RGD:13513923
NCBI chrNW_004936626:372,893...460,884
Ensembl chrNW_004936626:373,433...460,788
G
Gria1
glutamate ionotropic receptor AMPA type subunit 1
ISO
protein:increased phosphorylation:central amygdaloid nucleus (rat)
RGD
PMID:30638118
RGD:405101698
NCBI chrNW_004936515:8,937,391...9,236,438
Ensembl chrNW_004936515:8,940,009...9,083,151
G
Icam1
intercellular adhesion molecule 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28642177
NCBI chrNW_004936659:616,570...627,172
Ensembl chrNW_004936659:616,752...627,174
G
Il1b
interleukin 1 beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28642177
NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165
G
Itgb1
integrin subunit beta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25668593
NCBI chrNW_004936574:1,465,981...1,495,717
Ensembl chrNW_004936574:1,465,897...1,495,762
G
Lama1
laminin subunit alpha 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25668593
NCBI chrNW_004936670:359,343...511,126
Ensembl chrNW_004936670:359,582...484,539
G
Lamp2
lysosomal associated membrane protein 2
ISO
protein:increased expression:hippocampus:
RGD
PMID:28365875
RGD:13703062
NCBI chrNW_004936479:9,584,221...9,622,330
Ensembl chrNW_004936479:9,584,221...9,610,420
G
Lcn2
lipocalin 2
ISO
RGD
PMID:31539545
RGD:126781751
NCBI chrNW_004936487:15,721,752...15,725,396
Ensembl chrNW_004936487:15,721,684...15,728,221
G
LOC101961588
cytochrome P450 2D17
treatment
ISO
RGD
PMID:26068867
RGD:401901590
NCBI chrNW_004936718:153,340...157,966
G
Mapt
microtubule associated protein tau
treatment
ISO
RGD
PMID:25771151 PMID:26484783 PMID:26729399 PMID:28412141
RGD:13800902 RGD:13800909 RGD:13800912 RGD:13800917
NCBI chrNW_004936541:2,381,411...2,479,984
G
Mettl14
methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit
ISO
mRNA:decreased expression:cerebral cortex
RGD
PMID:31992337
RGD:329901857
NCBI chrNW_004936869:568,324...589,972
Ensembl chrNW_004936869:568,840...590,269
G
Mmp2
matrix metallopeptidase 2
ISO
protein:increased expression:cerebral cortex
RGD
PMID:27614125
RGD:329961568
NCBI chrNW_004936475:7,801,356...7,825,831
Ensembl chrNW_004936475:7,801,277...7,825,851
G
Mmp9
matrix metallopeptidase 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25668593
NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793
G
Mpo
myeloperoxidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25668593
NCBI chrNW_004936490:4,809,773...4,819,070
Ensembl chrNW_004936490:4,809,631...4,819,070
G
Ncstn
nicastrin
ISO
RGD
PMID:18240300
RGD:13801189
NCBI chrNW_004936740:285,789...301,918
Ensembl chrNW_004936740:285,657...302,111
G
Nfe2l2
NFE2 like bZIP transcription factor 2
ISO
protein:increased expression:brain:
RGD
PMID:30855558
RGD:26884463
NCBI chrNW_004936509:6,589,967...6,621,171
Ensembl chrNW_004936509:6,590,630...6,620,262
G
Ngf
nerve growth factor
treatment
ISO
RGD
PMID:26285082
RGD:402463964
NCBI chrNW_004936627:635,784...641,290
Ensembl chrNW_004936627:635,788...645,364
G
Nmnat1
nicotinamide nucleotide adenylyltransferase 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:27822499
NCBI chrNW_004936623:3,862,234...3,891,849
Ensembl chrNW_004936623:3,870,031...3,891,849
G
Nos2
nitric oxide synthase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28642177
NCBI chrNW_004936538:4,052,277...4,097,051
Ensembl chrNW_004936538:4,052,448...4,097,051
G
Nox1
NADPH oxidase 1
ISO
protein:increased expression:cerebral cortex
RGD
PMID:27614125
RGD:329961568
NCBI chrNW_004936584:6,023,960...6,040,041
Ensembl chrNW_004936584:6,024,008...6,039,866
G
Nr3c1
nuclear receptor subfamily 3 group C member 1
ISO
mRNA:decreased expression:hippocampus, hypothalamus protein:increased phosphorylation:amygdala
RGD
PMID:30638118 PMID:36637480
RGD:405101698 RGD:408364984
NCBI chrNW_004936504:10,960,069...11,056,834
Ensembl chrNW_004936504:10,959,192...11,056,856
G
Ntrk2
neurotrophic receptor tyrosine kinase 2
ISO
mRNA:increased expression:dentate gyrus
RGD
PMID:10925157
RGD:596936229
NCBI chrNW_004936680:267,850...621,467
Ensembl chrNW_004936680:267,596...615,928
G
Ocln
occludin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25668593
NCBI chrNW_004936480:99,516...152,834
Ensembl chrNW_004936480:98,371...152,413
G
Parp1
poly(ADP-ribose) polymerase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15829224 PMID:28642177
NCBI chrNW_004936526:3,102,468...3,147,601
Ensembl chrNW_004936526:3,102,039...3,147,642
G
Pde10a
phosphodiesterase 10A
ISO
RGD
PMID:29215295
RGD:13513923
NCBI chrNW_004936489:15,401,248...15,671,594
Ensembl chrNW_004936489:15,400,629...15,671,600
G
Pdyn
prodynorphin
ISO
mRNA:increased expression:hippocampus
RGD
PMID:12626770
RGD:633616
NCBI chrNW_004936485:16,559,371...16,571,461
Ensembl chrNW_004936485:16,559,217...16,571,678
G
Phactr1
phosphatase and actin regulator 1
treatment
ISO
RGD
PMID:36571365
RGD:401901253
NCBI chrNW_004936534:42,354...323,735
Ensembl chrNW_004936534:42,433...536,171
G
Ppp3r1
protein phosphatase 3 regulatory subunit B, alpha
ISO
RGD
PMID:20713027
RGD:13830881
NCBI chrNW_004936491:12,623,931...12,654,463
Ensembl chrNW_004936491:12,623,349...12,654,502 Ensembl chrNW_004936491:12,623,349...12,654,502
G
Ppp3r2
protein phosphatase 3 regulatory subunit B, beta
ISO
RGD
PMID:20713027
RGD:13830881
NCBI chrNW_004936524:9,742,788...9,743,327
G
Psen1
presenilin 1
ISO
RGD
PMID:18240300
RGD:13801189
NCBI chrNW_004936488:2,464,623...2,528,807
Ensembl chrNW_004936488:2,464,527...2,530,065
G
Ptgs2
prostaglandin-endoperoxide synthase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28642177
NCBI chrNW_004936481:3,821,564...3,828,086
G
Rela
RELA proto-oncogene, NF-kB subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25668593 PMID:28642177
NCBI chrNW_004936599:3,800,142...3,810,583
Ensembl chrNW_004936599:3,801,636...3,809,813
G
Sox2
SRY-box transcription factor 2
treatment
ISO
RGD
PMID:26296359
RGD:597538582
NCBI chrNW_004936566:1,630,698...1,632,607
Ensembl chrNW_004936566:1,631,822...1,632,613
G
Tgfb1
transforming growth factor beta 1
treatment
ISO
RGD
PMID:28433746
RGD:14995478
NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272
G
Tnf
tumor necrosis factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28642177
NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766
G
Tp53
tumor protein p53
treatment
ISO
RGD
PMID:27553877
RGD:14995939
NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425
G
Ube4b
ubiquitination factor E4B
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:27822499
NCBI chrNW_004936623:3,934,439...4,051,083
Ensembl chrNW_004936623:3,934,310...4,051,146
G
Wnt3a
Wnt family member 3A
treatment
ISO
RGD
PMID:26296359
RGD:597538582
NCBI chrNW_004936864:150,742...179,205
Ensembl chrNW_004936864:150,732...192,423
G
F7
coagulation factor VII
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:20370756
NCBI chrNW_004936472:505,751...515,375
Ensembl chrNW_004936472:505,751...514,339
G
Abcc8
ATP binding cassette subfamily C member 8
treatment
ISO
RGD
PMID:18854840
RGD:2325137
NCBI chrNW_004936528:1,608,782...1,682,873
Ensembl chrNW_004936528:1,608,757...1,682,975
G
Tp53
tumor protein p53
ISO
RGD
PMID:22977862
RGD:8547771
NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425
G
Adrb2
adrenoceptor beta 2
ISO
mRNA:increased expression:Vestibulocochlear nerve:
RGD
PMID:22178544
RGD:8548530
NCBI chrNW_004936504:5,985,407...5,987,453
Ensembl chrNW_004936504:5,985,960...5,987,210
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