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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Craniocerebral Trauma
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Accession:DOID:9007621 term browser browse the term
Definition:Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage.
Synonyms:exact_synonym: Craniocerebral Injuries;   Craniocerebral Injury;   Craniocerebral Traumas;   Crushing Skull Injuries;   Crushing Skull Injury;   Forehead Trauma;   Forehead Traumas;   Frontal Region Trauma;   Frontal Region Traumas;   Head Injuries;   Head Injury;   Head Trauma;   Head Traumas;   Minor Head Injuries;   Minor Head Injury;   Multiple Head Injuries;   Multiple Head Injury;   Occipital Region Trauma;   Occipital Region Traumas;   Occipital Trauma;   Occipital Traumas;   Open Head Injuries;   Open Head Injury;   Parietal Region Trauma;   Parietal Region Traumas;   Superficial Head Injuries;   Superficial Head Injury;   Temporal Region Trauma;   Temporal Region Traumas
 primary_id: MESH:D006259;   RDO:0005059
 xref: EFO:0009505


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Craniocerebral Trauma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADNP activity dependent neuroprotector homeobox ISO RGD PMID:11123362 RGD:2312784 NCBI chr20:50,888,918...50,931,437
Ensembl chr20:50,888,916...50,931,437 		JBrowse link
G IL1A interleukin 1 alpha IEP protein:increased expression:microglial cell RGD PMID:7830934 RGD:10045949 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G POSTN periostin ISO RGD PMID:17878602 RGD:10041014 NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844 		JBrowse link
G SERPINC1 serpin family C member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:8810955 NCBI chr 1:173,903,800...173,917,327
Ensembl chr 1:173,903,800...173,917,327 		JBrowse link
Acute Subdural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPO erythropoietin treatment IDA RGD PMID:23415790 RGD:10401075 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G F7 coagulation factor VII EXP CTD Direct Evidence: therapeutic CTD PMID:12503044 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 treatment ISO RGD PMID:15379997 RGD:329969897 NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976 		JBrowse link
brain compression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFL1 cofilin 1 treatment IEP RGD PMID:25708984 RGD:12738361 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026 		JBrowse link
Brain Concussion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 ISO RGD PMID:26448536 RGD:13506960 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G DRD3 dopamine receptor D3 ISO RGD PMID:26448536 RGD:13506960 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407 		JBrowse link
G DRD4 dopamine receptor D4 ISO RGD PMID:26448536 RGD:13506960 NCBI chr11:637,269...640,706
Ensembl chr11:637,269...640,706 		JBrowse link
G IL6 interleukin 6 treatment ISO RGD PMID:27113205 RGD:11062140 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
Brain Contusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 ameliorates ISO RGD PMID:31654641 RGD:408418727 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:28140659 RGD:13782305 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 treatment ISO RGD PMID:28140659 RGD:13782305 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G IL1B interleukin 1 beta treatment ISO RGD PMID:31654641 RGD:408418727 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G PYCARD PYD and CARD domain containing treatment ISO RGD PMID:19401709 RGD:5491174 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G TNF tumor necrosis factor treatment ISO RGD PMID:31654641 RGD:408418727 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
Brain Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 treatment ISO RGD PMID:21107131 RGD:12791995 NCBI chr11:17,392,498...17,476,845
Ensembl chr11:17,392,498...17,476,894 		JBrowse link
G ACAN aggrecan ISO mRNA:increased expression:fascia dentata (rat) RGD PMID:18511192 RGD:2315807 NCBI chr15:88,803,436...88,875,353
Ensembl chr15:88,803,436...88,875,353 		JBrowse link
G ACTR2 actin related protein 2 ISO mRNA, protein:decreased expression:hippocampus (rat) RGD PMID:22120305 RGD:11530046 NCBI chr 2:65,227,831...65,271,253
Ensembl chr 2:65,227,788...65,271,253 		JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 ISO RGD PMID:16689670 RGD:2325298 NCBI chr18:904,411...912,172
Ensembl chr18:904,871...912,172 		JBrowse link
G ADRA1A adrenoceptor alpha 1A ISO mRNA:increased expression:frontal cortex RGD PMID:20974230 RGD:5688366 NCBI chr 8:26,748,150...26,867,379
Ensembl chr 8:26,748,150...26,867,278 		JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO protein:increased expression:brain (rat) RGD PMID:22915134 PMID:24859607 PMID:22491548 RGD:7245513, RGD:8696001, RGD:7245557 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G AIF1 allograft inflammatory factor 1 ISO protein:increased expression:cerebral cortex (rat) RGD PMID:19520144 RGD:2313020 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 ISO protein:increased expression:nucleus: RGD PMID:12091479 RGD:10053567 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 IEP protein:increased phosphorylation:brain, neuron RGD PMID:16234845 RGD:5509090 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ALB albumin EXP CTD Direct Evidence: marker/mechanism CTD PMID:7909931 PMID:17188501 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor IEP protein:increased expression:urine RGD PMID:14592616 RGD:6904155 NCBI chr 9:114,060,127...114,078,300
Ensembl chr 9:114,060,127...114,078,328 		JBrowse link
G ANK3 ankyrin 3 ISO RGD PMID:20557305 RGD:6767288 NCBI chr10:60,026,298...60,733,528
Ensembl chr10:60,026,298...60,733,490 		JBrowse link
G ANP32A acidic nuclear phosphoprotein 32 family member A ISO RGD PMID:24385964 RGD:10401136 NCBI chr15:68,778,535...68,820,895
Ensembl chr15:68,778,535...68,820,897 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 ISO protein:increased expression:cerebral cortex RGD PMID:11567033 RGD:2325751 NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,149...98,735,433 		JBrowse link
G APBB1 amyloid beta precursor protein binding family B member 1 ISO mRNA:increased expression:brain RGD PMID:12707777 RGD:2301208 NCBI chr11:6,395,124...6,419,453
Ensembl chr11:6,395,125...6,419,414 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11447995 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772 		JBrowse link
G APOD apolipoprotein D ISO mRNA, protein:increased expression:cerebral cortex, glia cell, neuron RGD PMID:10501208 RGD:2311202 NCBI chr 3:195,568,705...195,583,940
Ensembl chr 3:195,568,705...195,584,033 		JBrowse link
G APOE apolipoprotein E IEA GAD PMID:15118671 RGD:1331525 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G APP amyloid beta precursor protein IEP protein:increased expression:hippocampus RGD PMID:16300758 RGD:10054281 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G AQP4 aquaporin 4 ISO protein:increased expression:cerebral cortex RGD PMID:21083433 PMID:21488209 RGD:5148014, RGD:5148034 NCBI chr18:26,852,038...26,865,803
Ensembl chr18:26,852,043...26,865,771 		JBrowse link
G ASIC1 acid sensing ion channel subunit 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21307247 NCBI chr12:50,057,596...50,083,622
Ensembl chr12:50,057,548...50,083,611 		JBrowse link
G ASTN1 astrotactin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:14499481 NCBI chr 1:176,857,321...177,164,712
Ensembl chr 1:176,857,302...177,164,973 		JBrowse link
G ATG12 autophagy related 12 ISO protein:altered localization:brain RGD PMID:18059433 RGD:2301217 NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837 		JBrowse link
G ATP5PD ATP synthase peripheral stalk subunit d treatment ISO RGD PMID:26813465 RGD:13800884 NCBI chr17:75,038,863...75,046,969
Ensembl chr17:75,038,863...75,046,985 		JBrowse link
G AVPR1A arginine vasopressin receptor 1A ISO mRNA:increased expression:cerebral cortex RGD PMID:17244947 RGD:2300372 NCBI chr12:63,142,759...63,151,201
Ensembl chr12:63,142,759...63,151,201 		JBrowse link
G BAD BCL2 associated agonist of cell death ISO mRNA, protein:increased expression:cerebral cortex RGD PMID:15941375 RGD:2292694 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:20888848 RGD:10054247 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCAT1 branched chain amino acid transaminase 1 ISO Protein:increased expression:neurons RGD PMID:10686349 RGD:631308 NCBI chr12:24,810,024...24,949,340
Ensembl chr12:24,810,024...24,949,101 		JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:18093155 PMID:20888848 RGD:2293059, RGD:10054247 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BDNF brain derived neurotrophic factor IEP
EXP		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:15500971 PMID:21269288 PMID:20544832 RGD:4891136 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BECN1 beclin 1 ISO
EXP		 protein:increased expression:neuron, astrocyte
CTD Direct Evidence: therapeutic
protein:increased expression:hippocampus
protein:increased expression:brain		 CTD
RGD		 PMID:34929507 PMID:18500386 PMID:24221859 PMID:16874043 RGD:6483098, RGD:11558018, RGD:6483314 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ISO mRNA, protein:increased expression:brain, astrocyte, neuron RGD PMID:15453988 RGD:2293136 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G BMP6 bone morphogenetic protein 6 ISO protein:increased expression:brain, astrocyte, neuron RGD PMID:16388909 RGD:2289020 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 ISO mRNA:increased expression:dentate gyrus, neuron RGD PMID:9080432 RGD:5129488 NCBI chr 2:202,376,327...202,567,749
Ensembl chr 2:202,376,327...202,567,751 		JBrowse link
G BYSL bystin like ISO mRNA, protein:increased expression:substantia nigra, striatum (rat) RGD PMID:15305856 RGD:2316201 NCBI chr 6:41,908,759...41,933,046
Ensembl chr 6:41,921,229...41,933,050 		JBrowse link
G C1QA complement C1q A chain ISO RGD PMID:23808389 RGD:10054313 NCBI chr 1:22,636,463...22,639,678
Ensembl chr 1:22,635,077...22,639,678 		JBrowse link
G C3 complement C3 ISO RGD PMID:23808389 RGD:10054313 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G CASK calcium/calmodulin dependent serine protein kinase ISO RGD PMID:25089700 RGD:11576302 NCBI chr  X:41,514,934...41,923,554
Ensembl chr  X:41,514,934...41,923,554 		JBrowse link
G CASP1 caspase 1 ISO mRNA, protein:increased expression:brain RGD PMID:17188500 RGD:2315917 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CASP12 caspase 12 (gene/pseudogene) severity ISO mRNA, protein:increased expression, increased activity:cerebral cortex, hippocampus, neuron, astrocyte RGD PMID:14675152 RGD:2311485 NCBI chr11:104,883,286...104,898,460
Ensembl chr11:104,885,718...104,898,670 		JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:20888848 RGD:10054247 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 ISO protein:altered localization RGD PMID:15590916 RGD:1624191 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CAST calpastatin severity ISO mRNA:increased expression:cerebral cortex RGD PMID:15307896 RGD:5509821 NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,247,756...96,779,595
Ensembl chr 5:96,247,756...96,779,595 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO
EXP		 protein:increased expression:brain, neuron
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21549006 PMID:19210118 PMID:11113322 RGD:2306999, RGD:9587789 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL20 C-C motif chemokine ligand 20 treatment ISO RGD PMID:22040257 RGD:7483630 NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO mRNA:increased expression:hippocampus RGD PMID:24344922 RGD:8552265 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CD14 CD14 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD40 CD40 molecule treatment ISO RGD PMID:23924471 RGD:7248749 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD40LG CD40 ligand treatment ISO RGD PMID:11755016 PMID:25972624 RGD:8547803, RGD:11344972 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO protein:increased expression:nucleus: RGD PMID:9914434 RGD:8662346 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO protein:decreased expression:cerebral cortex RGD PMID:21728064 RGD:10045359 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha ISO mRNA, protein:increased expression:cerebral cortex (mouse) RGD PMID:19833158 RGD:10401206 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO
EXP		 mRNA, protein:increased expression:cerebral cortex (mouse)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21549006 PMID:19833158 RGD:10401206 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,734...50,192,690 		JBrowse link
G CES1 carboxylesterase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
G CFB complement factor B EXP CTD Direct Evidence: marker/mechanism CTD PMID:17474994 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 7:136,868,652...137,020,213
Ensembl chr 7:136,868,652...137,020,255 		JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr15:32,030,483...32,173,018
Ensembl chr15:31,923,438...32,173,018 		JBrowse link
G CKMT1B creatine kinase, mitochondrial 1B treatment ISO RGD PMID:24252176 RGD:11565089 NCBI chr15:43,592,857...43,599,406
Ensembl chr15:43,593,054...43,604,901
Ensembl chr15:43,593,054...43,604,901 		JBrowse link
G CLEC4E C-type lectin domain family 4 member E EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr12:8,533,275...8,540,905
Ensembl chr12:8,533,305...8,540,905 		JBrowse link
G CNP 2',3'-cyclic nucleotide 3' phosphodiesterase ISO protein:increased expression:hippocampus RGD PMID:20215974 RGD:6483336 NCBI chr17:41,966,795...41,977,740
Ensembl chr17:41,966,763...41,977,740 		JBrowse link
G COMT catechol-O-methyltransferase ISO protein:increased expression:hippocampus RGD PMID:17240060 RGD:2289740 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975 		JBrowse link
G CRP C-reactive protein disease_progression IEP RGD PMID:24456846 RGD:9585646 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CSF2 colony stimulating factor 2 disease_progression ISO RGD PMID:21515263 RGD:5686795 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G CSF3 colony stimulating factor 3 treatment IDA
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21549006 PMID:24239694 RGD:11039431 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813 		JBrowse link
G CSPG4 chondroitin sulfate proteoglycan 4 ISO protein:altered expression:cerebral cortex RGD PMID:19473238 RGD:5686860 NCBI chr15:75,674,322...75,713,466
Ensembl chr15:75,674,322...75,712,848 		JBrowse link
G CUL5 cullin 5 ISO mRNA, protein:decreased expression:cerebral cortex, hippocampus RGD PMID:17010517 RGD:2301432 NCBI chr11:108,008,898...108,107,761
Ensembl chr11:108,008,898...108,107,761 		JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO mRNA:increased expression:choroid plexus, cerebral cortex RGD PMID:19471279 RGD:5135009 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO protein:increased expression:brain, neuron RGD PMID:19210118 RGD:2306999 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO mRNA:increased expression:hindbrain RGD PMID:16329132 RGD:1599699 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G CYP4F12 cytochrome P450 family 4 subfamily F member 12 ISO RGD PMID:18847377 RGD:2301705 NCBI chr19:15,673,087...15,697,174
Ensembl chr19:15,673,018...15,697,174 		JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:15774263 RGD:7243841 NCBI chr 5:39,371,677...39,424,980
Ensembl chr 5:39,371,675...39,462,300 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:19429151 RGD:9588608 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DPYSL2 dihydropyrimidinase like 2 ISO protein:increased degradation:cerebral cortex, hippocampus RGD PMID:17402852 RGD:2303056 NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178 		JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:18509630 RGD:2311580 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G DUSP5 dual specificity phosphatase 5 ISO mRNA:increased expression:cerebral cortex RGD PMID:12503083 RGD:2317873 NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha ISO RGD PMID:11526986 RGD:10395358 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516 		JBrowse link
G EIF3E eukaryotic translation initiation factor 3 subunit E treatment ISO RGD PMID:22960363 RGD:10395371 NCBI chr 8:108,201,216...108,248,717
Ensembl chr 8:108,162,787...108,443,496 		JBrowse link
G ELK1 ETS transcription factor ELK1 ISO RGD PMID:15362724 RGD:7488910 NCBI chr  X:47,635,520...47,650,604
Ensembl chr  X:47,635,520...47,650,604 		JBrowse link
G ENO2 enolase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34533065 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 treatment ISO RGD PMID:22960363 RGD:10395371 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697 		JBrowse link
G EPHA4 EPH receptor A4 IEP protein:increased expression, increased activity:astrocyte RGD PMID:22318127 RGD:5688763 NCBI chr 2:221,418,027...221,574,202
Ensembl chr 2:221,418,027...221,574,202 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO RGD PMID:21075124 RGD:5688356 NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564 		JBrowse link
G EPO erythropoietin treatment IDA
EXP
ISO		 CTD Direct Evidence: therapeutic
mRNA:increased expression:brain:		 CTD
RGD		 PMID:20833152 PMID:23063952 PMID:18093155 RGD:10401061, RGD:2293059 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G EPOR erythropoietin receptor ISO mRNA:increased expression:brain: RGD PMID:18093155 RGD:2293059 NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342 		JBrowse link
G F2 coagulation factor II, thrombin severity IDA RGD PMID:21355766 RGD:5147766 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G FAS Fas cell surface death receptor ISO mRNA:increased expression:hippocampus
associated with Hyperoxia		 RGD PMID:16078565 PMID:19107989 RGD:1600354, RGD:8662854 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FGF2 fibroblast growth factor 2 EXP CTD Direct Evidence: therapeutic CTD PMID:21269288 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FMR1 fragile X messenger ribonucleoprotein 1 ISO protein:altered localization:hippocampus (rat) RGD PMID:16510718 RGD:11667962 NCBI chr  X:147,911,919...147,951,125
Ensembl chr  X:147,911,919...147,951,125 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:9630518 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190 		JBrowse link
G FOXP1 forkhead box P1 treatment ISO RGD PMID:26842647 RGD:11561903 NCBI chr 3:70,954,708...71,583,978
Ensembl chr 3:70,954,693...71,583,978 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase ISO protein:decreased expression:hippocampus RGD PMID:18501200 RGD:2307353 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr15:26,543,552...26,773,763
Ensembl chr15:26,543,552...26,939,539 		JBrowse link
G GABRG3 gamma-aminobutyric acid type A receptor subunit gamma3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr15:26,971,181...27,541,984
Ensembl chr15:26,971,181...27,541,984 		JBrowse link
G GDNF glial cell derived neurotrophic factor ISO mRNA:increased expression:brain RGD PMID:18501516 RGD:2324932 NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041 		JBrowse link
G GJA1 gap junction protein alpha 1 treatment ISO RGD PMID:23485053 RGD:8662424 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GJA5 gap junction protein alpha 5 ISO protein:increased expression:cerebral artery RGD PMID:21895483 RGD:7207391 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362 		JBrowse link
G GPX1 glutathione peroxidase 1 ISO mRNA:decreased expression:hippocampus, neuron RGD PMID:15791111 RGD:2306624 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GRM8 glutamate metabotropic receptor 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 7:126,438,598...127,252,941
Ensembl chr 7:126,438,598...127,253,093 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:24675465 PMID:22643085 RGD:10045646 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GSN gelsolin ISO RGD PMID:14588109 RGD:1599864 NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843 		JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO mRNA,protein:decreased expression:hippocampus: RGD PMID:11726545 RGD:9686434 NCBI chr 5:45,254,948...45,696,380
Ensembl chr 5:45,254,948...45,696,498 		JBrowse link
G HMGB1 high mobility group box 1 treatment ISO RGD PMID:22915134 RGD:7245513 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:18562561 RGD:5508455 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:23470432 RGD:10755702 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HP haptoglobin ISO mRNA:increased expression:liver RGD PMID:23172820 RGD:11041806 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A ISO
EXP		 mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21549006 PMID:21549006 RGD:5147593 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO protein:increased expression:cerebral white matter (rat) RGD PMID:22067617 RGD:5688785 NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO RGD PMID:11746764 RGD:6480530 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,305,813 		JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO RGD PMID:22465320 RGD:6482178 NCBI chr10:90,740,823...90,858,039
Ensembl chr10:90,740,823...90,858,039 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:brain: RGD PMID:16230799 RGD:11522716 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IFNL3 interferon lambda 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr19:39,243,455...39,245,250
Ensembl chr19:39,243,455...39,245,250 		JBrowse link
G IGF1 insulin like growth factor 1 treatment IDA human protein in a rat model RGD PMID:9344566 RGD:12904928 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGF2 insulin like growth factor 2 ISO mRNA:decreased expression:brain RGD PMID:11123717 RGD:5509972 NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391 		JBrowse link
G IL10 interleukin 10 severity
treatment		 IEP
EXP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21549006 PMID:23075771 PMID:23971414 RGD:7364822, RGD:7364983 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL12RB2 interleukin 12 receptor subunit beta 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 1:67,307,364...67,398,724
Ensembl chr 1:67,307,364...67,398,724 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977 		JBrowse link
G IL16 interleukin 16 ISO RGD PMID:17983426 RGD:5024939 NCBI chr15:81,182,712...81,314,058
Ensembl chr15:81,159,575...81,314,058 		JBrowse link
G IL17RD interleukin 17 receptor D EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 3:57,089,982...57,170,317
Ensembl chr 3:57,089,982...57,170,306 		JBrowse link
G IL18 interleukin 18 severity ISO mRNA, protein:increased expression:brain RGD PMID:17188500 PMID:17188500 RGD:2315917, RGD:2315917 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096 		JBrowse link
G IL18R1 interleukin 18 receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 2:102,355,796...102,398,776
Ensembl chr 2:102,311,529...102,398,777 		JBrowse link
G IL1A interleukin 1 alpha ISO
EXP		 mRNA, protein:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21549006 PMID:16024175 RGD:2311098 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta ISO
EXP		 mRNA, protein:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism
protein:increased expression:brain, cerebrospinal fluid
mRNA, protein:increased expression:brain		 CTD
RGD		 PMID:19800810 PMID:21549006 PMID:16024175 PMID:22503903 PMID:17612572 RGD:2311098, RGD:6482651, RGD:1626652 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1R1 interleukin 1 receptor type 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 2:102,070,390...102,179,874
Ensembl chr 2:102,064,544...102,179,874 		JBrowse link
G IL1RN interleukin 1 receptor antagonist EXP CTD Direct Evidence: therapeutic CTD PMID:25665855 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL2 interleukin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL3 interleukin 3 disease_progression ISO
IEP		 protein: increased expression: brain: microdialysis perfusate RGD PMID:21515263 PMID:20717122 RGD:5686795, RGD:5686886 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204 		JBrowse link
G IL31RA interleukin 31 receptor A EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 5:55,839,789...55,922,850
Ensembl chr 5:55,851,357...55,922,854 		JBrowse link
G IL4 interleukin 4 ISO protein:decreased expression:plasma RGD PMID:24519543 RGD:10402802 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL5 interleukin 5 treatment ISO RGD PMID:24602693 PMID:24530657 RGD:11522766, RGD:11522770 NCBI chr 5:132,541,445...132,556,815
Ensembl chr 5:132,541,445...132,556,838 		JBrowse link
G IL6 interleukin 6 ISO
EXP		 protein:increased expression:cerebrospinal fluid (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19800810 PMID:21549006 PMID:23159883 PMID:10027774 RGD:11049549 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL7 interleukin 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 8:78,675,044...78,805,463
Ensembl chr 8:78,675,743...78,805,523 		JBrowse link
G IL9R interleukin 9 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr  X:155,997,696...156,013,020
NCBI chr  Y:57,184,072...57,197,869
Ensembl chr  X:155,997,696...156,013,017
Ensembl chr  Y:155,997,696...156,013,017 		JBrowse link
G IRF1 interferon regulatory factor 1 ISO
EXP		 mRNA:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21549006 PMID:12503083 RGD:2317873 NCBI chr 5:132,481,609...132,490,773
Ensembl chr 5:132,440,440...132,508,719 		JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:21596098 RGD:6483023 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 ISO RGD PMID:20861444 RGD:8662901 NCBI chr 1:160,037,467...160,070,160
Ensembl chr 1:159,998,651...160,070,483 		JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:cerebral cortex RGD PMID:21307798 PMID:19733172 RGD:5684382, RGD:5684402 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G LEP leptin ISO RGD PMID:21276361 RGD:5128517 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LSG1 large 60S subunit nuclear export GTPase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:14499481 NCBI chr 3:194,640,791...194,672,191
Ensembl chr 3:194,640,791...194,672,463 		JBrowse link
G LY86 lymphocyte antigen 86 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 6:6,588,720...6,654,982
Ensembl chr 6:6,588,108...6,654,983 		JBrowse link
G MAG myelin associated glycoprotein susceptibility ISO RGD PMID:17156367 RGD:9685230 NCBI chr19:35,292,161...35,313,807
Ensembl chr19:35,292,125...35,313,807 		JBrowse link
G MAP1B microtubule associated protein 1B ISO protein:increased expression, increased phosphorylation:brain RGD PMID:10906717 RGD:2304029 NCBI chr 5:72,107,475...72,209,565
Ensembl chr 5:72,107,234...72,209,565 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:24221859 RGD:11558018 NCBI chr20:34,546,844...34,560,345
Ensembl chr20:34,546,854...34,560,345 		JBrowse link
G MAP2 microtubule associated protein 2 ISO protein:decreased expression:cerebral cortex, neuron RGD PMID:21401443 PMID:20568963 RGD:6483087, RGD:6483089 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 treatment ISO associated with Subarachnoid Hemorrhage RGD PMID:27000704 PMID:33414375 PMID:26100626 RGD:155791672, RGD:155882440, RGD:155804286 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MBL2 mannose binding lectin 2 disease_progression ISO RGD PMID:18183030 RGD:12910935 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784 		JBrowse link
G MBP myelin basic protein ISO RGD PMID:18583256 RGD:7349333 NCBI chr18:76,978,833...77,133,708
Ensembl chr18:76,978,827...77,133,683 		JBrowse link
G MDM2 MDM2 proto-oncogene ISO protein:increased expression:brain cortex (rat) RGD PMID:15165363 RGD:2317397 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:15922484 RGD:1641989 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MIR132 microRNA 132 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr17:2,049,908...2,050,008
Ensembl chr17:2,049,908...2,050,008 		JBrowse link
G MIR144 microRNA 144 ISO RGD PMID:25089700 RGD:11576302 NCBI chr17:28,861,533...28,861,618
Ensembl chr17:28,861,533...28,861,618 		JBrowse link
G MIR153-2 microRNA 153-2 ISO RGD PMID:25089700 RGD:11576302 NCBI chr 7:157,574,336...157,574,422
Ensembl chr 7:157,574,336...157,574,422 		JBrowse link
G MIR183 microRNA 183 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 7:129,774,905...129,775,014
Ensembl chr 7:129,774,905...129,775,014 		JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19631748 PMID:16671440 PMID:24661104 RGD:1582656, RGD:13207312 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPO myeloperoxidase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MT-CO2 mitochondrially encoded cytochrome c oxidase II ISO mRNA, protein:increased expression:hippocampus RGD PMID:11686499 RGD:2302298 NCBI chr MT:7,586...8,269
Ensembl chr MT:7,586...8,269 		JBrowse link
G MT2A metallothionein 2A ISO mRNA:increased expression:liver (mouse)
mRNA:increased expression:dentate gyrus (rat)		 RGD PMID:22363575 PMID:15650329 RGD:6483812, RGD:6483847 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497 		JBrowse link
G MT3 metallothionein 3 treatment ISO RGD PMID:16314047 PMID:10595827 PMID:10218634 RGD:6480628, RGD:9685805, RGD:9685803 NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088 		JBrowse link
G MYOC myocilin ISO mRNA:increased expression:cerebral cortex (rat) RGD PMID:12799138 RGD:7401267 NCBI chr 1:171,635,417...171,652,688
Ensembl chr 1:171,635,417...171,652,688 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO protein:increased expression:lung: RGD PMID:18787991 PMID:25089700 RGD:5134971, RGD:11576302 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NGB neuroglobin severity ISO RGD PMID:21915648 RGD:9743963 NCBI chr14:77,265,483...77,271,206
Ensembl chr14:77,265,483...77,271,206 		JBrowse link
G NGFR nerve growth factor receptor treatment ISO RGD PMID:23940017 RGD:10414074 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO RGD PMID:11526986 RGD:10395358 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOX4 NADPH oxidase 4 EXP CTD Direct Evidence: therapeutic CTD PMID:36762617 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187 		JBrowse link
G NPPB natriuretic peptide B IEP
EXP		 associated with lung diseases;protein:increased expression:serum:
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:19803787 PMID:23837838 RGD:7247620 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945 		JBrowse link
G NPY neuropeptide Y ISO protein:increased expression:adrenal medulla RGD PMID:23570732 RGD:10448961 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 treatment ISO mRNA:increased expression:lung
associated with Subarachnoid Hemorrhage		 RGD PMID:18787991 PMID:20864352 RGD:5134971, RGD:11035222 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NT5E 5'-nucleotidase ecto ISO protein:altered expression:cerebral cortex (rat) RGD PMID:21337375 RGD:5134348 NCBI chr 6:85,450,083...85,495,784
Ensembl chr 6:85,449,584...85,495,791 		JBrowse link
G P2RY1 purinergic receptor P2Y1 ISO protein:increased expression:brain, astrocyte RGD PMID:19115395 RGD:2315811 NCBI chr 3:152,835,131...152,841,439
Ensembl chr 3:152,835,131...152,841,439 		JBrowse link
G PALLD palladin, cytoskeletal associated protein ISO protein:increased expression:brain, astrocyte RGD PMID:12932445 RGD:2325786 NCBI chr 4:168,497,052...168,928,441
Ensembl chr 4:168,497,052...168,928,457 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17640816 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO mRNA,protein:increased expression:brain: RGD PMID:11421591 RGD:9835358 NCBI chr12:79,584,879...79,690,964
Ensembl chr12:79,574,979...79,690,964 		JBrowse link
G PDE4D phosphodiesterase 4D ISO mRNA, protein:alternative form, decreased phosphorylation:brain RGD PMID:23057870 RGD:7327147 NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120 		JBrowse link
G PDGFA platelet derived growth factor subunit A ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr 7:497,258...520,700
Ensembl chr 7:497,258...520,296 		JBrowse link
G PDGFB platelet derived growth factor subunit B ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr 4:54,229,293...54,298,245
Ensembl chr 4:54,229,280...54,298,245 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:22658532 RGD:6484732 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
G PGLYRP1 peptidoglycan recognition protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr19:46,019,153...46,023,053
Ensembl chr19:46,019,153...46,023,053 		JBrowse link
G PGR progesterone receptor ISO RGD PMID:23211561 RGD:7248711 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G PHB1 prohibitin 1 ISO protein:increased oxidation:cerebral cortex RGD PMID:17518533 RGD:2292409 NCBI chr17:49,404,052...49,414,882
Ensembl chr17:49,404,049...49,414,905 		JBrowse link
G PHB2 prohibitin 2 ISO RGD PMID:24566151 RGD:12903261 NCBI chr12:6,965,327...6,970,753
Ensembl chr12:6,965,327...6,970,780 		JBrowse link
G PIAS1 protein inhibitor of activated STAT 1 ISO protein:decreased expression:brain, nucleus RGD PMID:21545521 RGD:8693413 NCBI chr15:68,054,315...68,193,847
Ensembl chr15:68,054,309...68,198,603 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO agonist more effective in combination with simvastatin (rat) RGD PMID:18562561 RGD:5508455 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha treatment ISO protein:decreased expression:frontal cortex (rat) RGD PMID:22642418 PMID:24345766 RGD:6484257, RGD:10059630 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha ISO
EXP		 protein: :hippocampus
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:14499481 PMID:19751097 RGD:6483311 NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278 		JBrowse link
G PRF1 perforin 1 IEP RGD PMID:20537642 RGD:6482807 NCBI chr10:70,597,348...70,602,741
Ensembl chr10:70,597,348...70,602,759 		JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO protein:increased expression:striatum, microglia (rat) RGD PMID:15234107 RGD:9850280 NCBI chr 1:70,852,358...71,047,816
Ensembl chr 1:70,852,353...71,047,816 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO
IEP		 protein:increased expression:microglia, macrophage
protein:increased expression:microglial cells, macrophage, endothelial cell		 RGD PMID:19719848 PMID:11565600 PMID:12005397 RGD:5688162, RGD:5688242, RGD:5688239 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12410334 PMID:20810888 PMID:21549006 PMID:21866634 PMID:19719848 RGD:5508191, RGD:5688162 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTPRZ1 protein tyrosine phosphatase receptor type Z1 ISO RGD PMID:12088737 RGD:727637 NCBI chr 7:121,873,161...122,062,036
Ensembl chr 7:121,873,089...122,062,036 		JBrowse link
G RCHY1 ring finger and CHY zinc finger domain containing 1 ISO protein:increased expression:cerebral cortex RGD PMID:21728064 RGD:10045359 NCBI chr 4:75,479,033...75,514,715
Ensembl chr 4:75,479,033...75,514,764 		JBrowse link
G REG3A regenerating family member 3 alpha ISO mRNA:increased expression:cerebral cortex (rat) RGD PMID:19351265 RGD:9831399 NCBI chr 2:79,157,006...79,159,753
Ensembl chr 2:79,157,003...79,159,753 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO protein:increased expression:ileum RGD PMID:18288455 RGD:2298787 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RET ret proto-oncogene ISO mRNA:increased expression:brain RGD PMID:18501516 RGD:2324932 NCBI chr10:43,077,069...43,130,351
Ensembl chr10:43,077,064...43,130,351 		JBrowse link
G RHOA ras homolog family member A ISO protein:increased expression:microglial cell, brain RGD PMID:17929039 RGD:2298888 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G ROBO1 roundabout guidance receptor 1 ISO mRNA:increased expression:brain
protein:increased expression:brain, immune cell		 RGD PMID:16262652 PMID:26550694 RGD:2316136, RGD:243048437 NCBI chr 3:78,597,239...79,767,998
Ensembl chr 3:78,597,239...79,767,998 		JBrowse link
G ROBO2 roundabout guidance receptor 2 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr 3:75,906,675...77,649,964
Ensembl chr 3:75,906,695...77,649,964 		JBrowse link
G ROBO3 roundabout guidance receptor 3 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr11:124,865,432...124,881,471
Ensembl chr11:124,865,432...124,881,471 		JBrowse link
G RPS27A ribosomal protein S27a ISO mRNA:decreased expression:cerebral cortex, hippocampus RGD PMID:17936732 RGD:11041870 NCBI chr 2:55,231,903...55,235,853
Ensembl chr 2:55,231,903...55,235,853 		JBrowse link
G S100B S100 calcium binding protein B severity IEP
EXP		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:11520488 PMID:21783483 PMID:21976236 RGD:5508761 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208 		JBrowse link
G SELE selectin E ISO protein:increased expression:brain RGD PMID:19107536 RGD:2313599 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705 		JBrowse link
G SERPINC1 serpin family C member 1 EXP CTD Direct Evidence: therapeutic CTD PMID:21534203 NCBI chr 1:173,903,800...173,917,327
Ensembl chr 1:173,903,800...173,917,327 		JBrowse link
G SERPINF1 serpin family F member 1 treatment IMP
ISO		 human gene in a rat model
protein:altered expression:cerebellum (rat)		 RGD PMID:20142768 PMID:17709187 RGD:8612994, RGD:8622925 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565 		JBrowse link
G SIRT1 sirtuin 1 treatment ISO RGD PMID:17970622 RGD:9497541 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SKP2 S-phase kinase associated protein 2 ISO protein:increased expression:brain RGD PMID:19852587 RGD:2315049 NCBI chr 5:36,152,111...36,193,530
Ensembl chr 5:36,151,989...36,196,849 		JBrowse link
G SLC18A3 solute carrier family 18 member A3 ISO protein:decreased expression:brain RGD PMID:18848922 RGD:5686682 NCBI chr10:49,610,310...49,612,720
Ensembl chr10:49,610,310...49,612,720 		JBrowse link
G SLIT1 slit guidance ligand 1 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr10:96,998,038...97,185,959
Ensembl chr10:96,998,038...97,185,959 		JBrowse link
G SLIT2 slit guidance ligand 2 exacerbates ISO RGD PMID:26550694 RGD:243048437 NCBI chr 4:20,251,905...20,620,561
Ensembl chr 4:20,251,905...20,620,561 		JBrowse link
G SLIT3 slit guidance ligand 3 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr 5:168,661,740...169,301,139
Ensembl chr 5:168,661,740...169,301,139 		JBrowse link
G SNCA synuclein alpha ISO RGD PMID:14637093 PMID:25089700 RGD:6480195, RGD:11576302 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G SNCB synuclein beta ISO RGD PMID:14637093 RGD:6480195 NCBI chr 5:176,620,082...176,630,534
Ensembl chr 5:176,620,082...176,630,556 		JBrowse link
G SNCG synuclein gamma ISO RGD PMID:14637093 RGD:6480195 NCBI chr10:86,955,759...86,963,258
Ensembl chr10:86,958,599...86,963,258 		JBrowse link
G SNW1 SNW domain containing 1 ISO mRNA, protein:increased expression:cerebral cortex (rat) RGD PMID:22965216 RGD:11035237 NCBI chr14:77,717,599...77,761,156
Ensembl chr14:77,717,599...77,761,207 		JBrowse link
G SOD1 superoxide dismutase 1 ISO RGD PMID:16248885 RGD:1581214 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 ISO
EXP		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:24462953 PMID:16248885 RGD:1581214 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO mRNA:increased expression:brain, blood vessel RGD PMID:9704602 RGD:2300066 NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975 		JBrowse link
G SSTR2 somatostatin receptor 2 ISO RGD PMID:11879809 RGD:2325002 NCBI chr17:73,165,010...73,176,633
Ensembl chr17:73,165,010...73,176,633 		JBrowse link
G SSTR3 somatostatin receptor 3 ISO RGD PMID:11879809 RGD:2325002 NCBI chr22:37,204,237...37,220,548
Ensembl chr22:37,204,237...37,212,477 		JBrowse link
G SSTR4 somatostatin receptor 4 ISO RGD PMID:11879809 RGD:2325002 NCBI chr20:23,035,312...23,039,237
Ensembl chr20:23,035,312...23,039,237 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO RGD PMID:21596098 RGD:6483023 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO protein:increased phosphorylation:brain RGD PMID:21596098 PMID:22145815 PMID:22827467 RGD:6483023, RGD:8694312, RGD:6892706 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STRN striatin ISO RGD PMID:16351572 RGD:2311293 NCBI chr 2:36,837,698...36,966,536
Ensembl chr 2:36,837,698...36,966,536 		JBrowse link
G TARDBP TAR DNA binding protein IEP RGD PMID:22101322 RGD:5687195 NCBI chr 1:11,012,654...11,030,528
Ensembl chr 1:11,012,344...11,030,528 		JBrowse link
G TF transferrin ISO RGD PMID:22538758 RGD:7244386 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641 		JBrowse link
G TH tyrosine hydroxylase ISO protein:decreased activity:striatum (rat) RGD PMID:21047500 RGD:5128822 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G THBD thrombomodulin onset IEP RGD PMID:17895610 RGD:5685007 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672 		JBrowse link
G TICAM2 TIR domain containing adaptor molecule 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 5:115,578,496...115,602,479
Ensembl chr 5:115,578,496...115,602,479 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 ISO mRNA:increased expression:brain, astrocytes RGD PMID:10719361 RGD:2290468 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO mRNA:increased expression:brain, neuron, microglial cell RGD PMID:10719361 RGD:2290468 NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387 		JBrowse link
G TJP1 tight junction protein 1 ISO RGD PMID:19889224 RGD:2325128 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915 		JBrowse link
G TLR1 toll like receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,787,555...38,856,817 		JBrowse link
G TLR2 toll like receptor 2 ISO
EXP		 mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21549006 PMID:18316784 RGD:2312713 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR4 toll like receptor 4 ISO
EXP		 mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21549006 PMID:18316784 RGD:2312713 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TLR9 toll like receptor 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
G TNF tumor necrosis factor EXP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19800810 PMID:21549006 PMID:10674461 RGD:13825262 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF13B TNF receptor superfamily member 13B EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr17:16,939,081...16,972,118
Ensembl chr17:16,929,816...16,972,118 		JBrowse link
G TNFRSF13C TNF receptor superfamily member 13C EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr22:41,922,032...41,926,806
Ensembl chr22:41,922,032...41,926,806 		JBrowse link
G TNFRSF14 TNF receptor superfamily member 14 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 1:2,554,234...2,563,829
Ensembl chr 1:2,555,639...2,565,382 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO
EXP		 protein:increased expression:brain
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21549006 PMID:17074049 RGD:1624183 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFSF10 TNF superfamily member 10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475 		JBrowse link
G TNFSF12 TNF superfamily member 12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr17:7,549,058...7,557,881
Ensembl chr17:7,548,508...7,557,890 		JBrowse link
G TRAF4 TNF receptor associated factor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr17:28,744,011...28,750,956
Ensembl chr17:28,744,011...28,750,956 		JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 ISO mRNA, protein:increased expression:cerebral cortex, hippocampus RGD PMID:20309649 RGD:9999437 NCBI chr21:44,353,621...44,442,644
Ensembl chr21:44,350,163...44,443,081 		JBrowse link
G UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 ISO mRNA:decreased expression:cerebral cortex, hippocampus (rat) RGD PMID:17936732 RGD:11041870 NCBI chr19:18,563,766...18,577,550
Ensembl chr19:18,571,730...18,577,550 		JBrowse link
G UCP2 uncoupling protein 2 IMP
EXP		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:12858170 PMID:12858170 RGD:7204436 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,061...73,982,843 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO
EXP		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:18065154 PMID:12230324 RGD:1580574 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VEGFB vascular endothelial growth factor B ISO mRNA, protein:increased expression:brain RGD PMID:12230324 RGD:1580574 NCBI chr11:64,234,584...64,239,264
Ensembl chr11:64,234,584...64,239,264 		JBrowse link
G VIM vimentin ISO protein:increased expression:brain RGD PMID:19728994 PMID:15527750 RGD:6480519, RGD:6480527 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G XDH xanthine dehydrogenase treatment ISO RGD PMID:26528358 RGD:13208950 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
Chronic Brain Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E susceptibility IAGP DNA:polymorphism:exon: RGD PMID:9214529 RGD:7495763 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G TARDBP TAR DNA binding protein IEP protein:increased expression:brain RGD PMID:20720505 RGD:5687179 NCBI chr 1:11,012,654...11,030,528
Ensembl chr 1:11,012,344...11,030,528 		JBrowse link
Closed Head Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 ISO protein:increased expression:neuron RGD PMID:16004578 RGD:6483315 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G GFAP glial fibrillary acidic protein ISO RGD PMID:8833197 RGD:6480531 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 IDA human protein in a rat model RGD PMID:17014847 RGD:13504858 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624 		JBrowse link
G IGF1 insulin like growth factor 1 IEP protein:decreased expression:serum: RGD PMID:12002507 RGD:8548865 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 IEP protein:decreased expression:serum: RGD PMID:12002507 RGD:8548865 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874 		JBrowse link
G VIM vimentin ISO RGD PMID:8833197 RGD:6480531 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
Corneal Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28038895 NCBI chr17:19,737,984...19,748,298
Ensembl chr17:19,737,984...19,748,943 		JBrowse link
G TP63 tumor protein p63 ISO RGD PMID:12167247 RGD:11568649 NCBI chr 3:189,596,746...189,897,276
Ensembl chr 3:189,631,389...189,897,276 		JBrowse link
Corneal Perforation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma ISO mRNA,protein:increased expression:corneal RGD PMID:15832292 RGD:8157597 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
Cranial Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 ISO mRNA:increased expression:superior cervical ganglion RGD PMID:16420416 RGD:2289006 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:15153618 RGD:4891994 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
Diffuse Brain Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G S100B S100 calcium binding protein B EXP CTD Direct Evidence: marker/mechanism CTD PMID:30076900 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208 		JBrowse link
Eye Burns term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 treatment ISO RGD PMID:22553604 RGD:7364851 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL1B interleukin 1 beta ISO protein:increased expression:retina RGD PMID:9618720 RGD:7794723 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO protein:increased expression:cornea, neutrophil, macrophage (rat) RGD PMID:24194635 RGD:8552904 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
Eye Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF2 fibroblast growth factor 2 ISO protein:increased expression:lens RGD PMID:15273655 PMID:15273655 RGD:8655664, RGD:8655664 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G MIR182 microRNA 182 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27208084 NCBI chr 7:129,770,383...129,770,492
Ensembl chr 7:129,770,383...129,770,492 		JBrowse link
G MIR183 microRNA 183 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27208084 NCBI chr 7:129,774,905...129,775,014
Ensembl chr 7:129,774,905...129,775,014 		JBrowse link
G MIR96 microRNA 96 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27208084 NCBI chr 7:129,774,692...129,774,769
Ensembl chr 7:129,774,692...129,774,769 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma treatment ISO RGD PMID:18658087 RGD:8552893 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
Facial Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1 adenylate cyclase activating polypeptide 1 ISO mRNA:increased expression:facial VII nucleus RGD PMID:19427307 RGD:2325258 NCBI chr18:904,411...912,172
Ensembl chr18:904,871...912,172 		JBrowse link
G ATF2 activating transcription factor 2 ISO RGD PMID:9813301 RGD:10047413 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382 		JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO RGD PMID:19922414 RGD:6892922 NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706 		JBrowse link
G CD59 CD59 molecule (CD59 blood group) ISO mRNA, protein:increased expression:facial VII nucleus RGD PMID:9846834 RGD:1600495 NCBI chr11:33,703,010...33,736,479
Ensembl chr11:33,703,010...33,736,479 		JBrowse link
G CLU clusterin ISO protein:increased expression:neuron,astrocyte RGD PMID:10800205 RGD:408418725 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G CSF1 colony stimulating factor 1 ISO protein:increased expression:facial VII nerve, microglial cell RGD PMID:20831658 RGD:5131509 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992 		JBrowse link
G CTSS cathepsin S ISO RGD PMID:17539023 RGD:5686912 NCBI chr 1:150,730,188...150,765,778
Ensembl chr 1:150,730,079...150,765,957 		JBrowse link
G GFRA1 GDNF family receptor alpha 1 ISO mRNA:increased expression:facial VII nucleus RGD PMID:9582449 RGD:6218984 NCBI chr10:116,056,925...116,274,705
Ensembl chr10:116,056,925...116,276,803 		JBrowse link
G HGF hepatocyte growth factor treatment ISO RGD PMID:21562589 RGD:8548634 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G MT3 metallothionein 3 treatment ISO RGD PMID:14625437 RGD:9685806 NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088 		JBrowse link
G NDUFA5 NADH:ubiquinone oxidoreductase subunit A5 ISO mRNA:increased expression:skeletal muscle RGD PMID:8875451 RGD:2302319 NCBI chr 7:123,536,997...123,601,651
Ensembl chr 7:123,536,997...123,557,904 		JBrowse link
G RET ret proto-oncogene ISO mRNA:increased expression:facial VII nucleus RGD PMID:9582449 RGD:6218984 NCBI chr10:43,077,069...43,130,351
Ensembl chr10:43,077,064...43,130,351 		JBrowse link
Hypoglossal Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1B activin A receptor type 1B ISO RGD PMID:9013782 RGD:151665480 NCBI chr12:51,951,699...51,997,078
Ensembl chr12:51,951,699...51,997,078 		JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 ISO mRNA:increased expression:hypoglossal nerve RGD PMID:11311987 RGD:5037239 NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409 		JBrowse link
G AIF1 allograft inflammatory factor 1 ISO RGD PMID:9698327 RGD:704401 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G CSNK2B casein kinase 2 beta ISO RGD PMID:11068334 RGD:11565824 NCBI chr 6:31,666,080...31,670,067
Ensembl chr 6:31,665,227...31,670,343 		JBrowse link
G FGF2 fibroblast growth factor 2 ISO RGD PMID:9183688 RGD:8655640 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO RGD PMID:9183688 RGD:8655640 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834 		JBrowse link
G GFRA1 GDNF family receptor alpha 1 ISO mRNA:increased expression:hypoglossal XII nerve RGD PMID:10407179 RGD:6218979 NCBI chr10:116,056,925...116,274,705
Ensembl chr10:116,056,925...116,276,803 		JBrowse link
G IL1R1 interleukin 1 receptor type 1 ISO mRNA:increased expression:hypoglossal nerve RGD PMID:11311987 RGD:5037239 NCBI chr 2:102,070,390...102,179,874
Ensembl chr 2:102,064,544...102,179,874 		JBrowse link
G MCAM melanoma cell adhesion molecule ISO RGD PMID:10076889 RGD:7364787 NCBI chr11:119,308,529...119,317,130
Ensembl chr11:119,308,529...119,321,521 		JBrowse link
G MME membrane metalloendopeptidase ISO RGD PMID:8201016 RGD:13801045 NCBI chr 3:155,024,202...155,183,729
Ensembl chr 3:155,024,124...155,183,704 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO RGD PMID:7769990 RGD:7327191 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta ISO RGD PMID:7769990 RGD:7327191 NCBI chr 1:84,078,079...84,238,498
Ensembl chr 1:84,078,062...84,238,498 		JBrowse link
G RET ret proto-oncogene ISO mRNA:increased expression:hypoglossal XII nerve RGD PMID:10407179 RGD:6218979 NCBI chr10:43,077,069...43,130,351
Ensembl chr10:43,077,064...43,130,351 		JBrowse link
G SMAD1 SMAD family member 1 ISO mRNA:increased expression:hypoglossal nucleus RGD PMID:17166487 RGD:1643227 NCBI chr 4:145,480,770...145,559,176
Ensembl chr 4:145,481,194...145,559,176 		JBrowse link
G SMAD2 SMAD family member 2 ISO mRNA:increased expression:hypoglossal nucleus RGD PMID:17166487 RGD:1643227 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146 		JBrowse link
G SMAD3 SMAD family member 3 ISO mRNA:increased expression:hypoglossal nucleus RGD PMID:17166487 RGD:1643227 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173 		JBrowse link
G SMAD4 SMAD family member 4 ISO mRNA:increased expression:hypoglossal nucleus RGD PMID:17166487 RGD:1643227 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G SMAD7 SMAD family member 7 ISO mRNA:increased expression:hypoglossal nucleus RGD PMID:17166487 RGD:1643227 NCBI chr18:48,919,853...48,950,965
Ensembl chr18:48,919,853...48,950,965 		JBrowse link
G SMAD9 SMAD family member 9 ISO mRNA:decreased expression:hypoglossal nucleus RGD PMID:17166487 RGD:1643227 NCBI chr13:36,844,831...36,920,854
Ensembl chr13:36,844,831...36,920,887 		JBrowse link
G TXNRD1 thioredoxin reductase 1 ISO mRNA, protein:increased expression:neuron RGD PMID:19833109 RGD:5133729 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307 		JBrowse link
Intracranial Subdural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GP6 glycoprotein VI platelet exacerbates ISO RGD PMID:21258336 RGD:401824683 NCBI chr19:55,013,705...55,038,264
Ensembl chr19:55,013,705...55,038,264 		JBrowse link
G MDM2 MDM2 proto-oncogene treatment ISO RGD PMID:34334113 RGD:155882538 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G ZEB2 zinc finger E-box binding homeobox 2 treatment ISO protein:increased expression:brain (rat) RGD PMID:34334113 PMID:34334113 RGD:155882538, RGD:155882538 NCBI chr 2:144,384,081...144,520,119
Ensembl chr 2:144,364,364...144,521,057 		JBrowse link
Mandibular Fractures term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 ISO mRNA:decreased expression:bone RGD PMID:19607804 RGD:5147852 NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648 		JBrowse link
G IHH Indian hedgehog signaling molecule ISO RGD PMID:23992905 RGD:12911207 NCBI chr 2:219,054,424...219,060,921
Ensembl chr 2:219,054,424...219,060,921 		JBrowse link
Oculomotor Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO mRNA:increased expression:motor neuron RGD PMID:21456016 RGD:5684341 NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751 		JBrowse link
Optic Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO protein:decreased expression:retina RGD PMID:22649251 RGD:329347828 NCBI chr 1:167,809,386...167,914,134
Ensembl chr 1:167,809,386...167,914,215 		JBrowse link
G ADNP activity dependent neuroprotector homeobox ISO RGD PMID:18414890 RGD:2312783 NCBI chr20:50,888,918...50,931,437
Ensembl chr20:50,888,916...50,931,437 		JBrowse link
G AMIGO3 adhesion molecule with Ig like domain 3 treatment ISO RGD PMID:23613963 RGD:14390159 NCBI chr 3:49,716,829...49,719,684
Ensembl chr 3:49,716,829...49,719,684 		JBrowse link
G AQP4 aquaporin 4 ISO RGD PMID:20216911 RGD:2326035 NCBI chr18:26,852,038...26,865,803
Ensembl chr18:26,852,043...26,865,771 		JBrowse link
G AQP9 aquaporin 9 ISO RGD PMID:20216911 RGD:2326035 NCBI chr15:58,138,169...58,185,911
Ensembl chr15:58,138,169...58,185,911 		JBrowse link
G ARG2 arginase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30618589 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708 		JBrowse link
G ATF2 activating transcription factor 2 ISO RGD PMID:10366744 RGD:10047417 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO mRNA:increased expression:optic nerve, retina RGD PMID:24357921 RGD:10054098 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator ISO mRNA:decreased expression:optic nerve, retina RGD PMID:24357921 RGD:10054098 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BDNF brain derived neurotrophic factor treatment IDA
ISO		 RGD PMID:15140649 PMID:9520478 PMID:11050383 RGD:8655584, RGD:8655637, RGD:8655586 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G C3 complement C3 ISO mRNA:increased expression:optic nerve RGD PMID:14577867 RGD:5129542 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G CDK2 cyclin dependent kinase 2 ISO mRNA:increased expression:retina RGD PMID:16723461 RGD:2293567 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CFL1 cofilin 1 treatment ISO RGD PMID:27443501 RGD:11568693 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026 		JBrowse link
G CLU clusterin ISO RGD PMID:14577867 RGD:5129542 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO mRNA:increased expression:retina (rat) RGD PMID:20187850 RGD:151665810 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372 		JBrowse link
G CSF3 colony stimulating factor 3 treatment IDA RGD PMID:20144610 RGD:11039471 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813 		JBrowse link
G CTSB cathepsin B ISO protein:increased expression:retina (rat) RGD PMID:18775855 RGD:2315508 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533 		JBrowse link
G EDN1 endothelin 1 ISO protein:increased expression:retina RGD PMID:18600494 RGD:4892579 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDNRA endothelin receptor type A ISO mRNA:increased expression:retina RGD PMID:18600494 RGD:4892579 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G EDNRB endothelin receptor type B ISO mRNA:increased expression:retina RGD PMID:18600494 RGD:4892579 NCBI chr13:77,895,487...77,975,527
Ensembl chr13:77,895,481...77,975,529 		JBrowse link
G EP300 E1A binding protein p300 ISO
IMP		 protein:decreased expression:retinal ganglion cell layer (rat)
human gene in rat model		 RGD PMID:21705428 PMID:21705428 RGD:7349392, RGD:7349392 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G FGF2 fibroblast growth factor 2 treatment IMP RGD PMID:14664816 RGD:8554854 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase ISO mRNA:increased expression:retina RGD PMID:33664770 RGD:329951020 NCBI chr16:53,703,963...54,121,941
Ensembl chr16:53,701,692...54,158,512 		JBrowse link
G GDNF glial cell derived neurotrophic factor ISO RGD PMID:15144875 RGD:6218970 NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041 		JBrowse link
G GFRA1 GDNF family receptor alpha 1 ISO RGD PMID:15144875 RGD:6218970 NCBI chr10:116,056,925...116,274,705
Ensembl chr10:116,056,925...116,276,803 		JBrowse link
G GFRA2 GDNF family receptor alpha 2 ISO RGD PMID:15144875 RGD:6218970 NCBI chr 8:21,690,398...21,812,345
Ensembl chr 8:21,690,398...21,812,357 		JBrowse link
G HGF hepatocyte growth factor treatment IDA RGD PMID:21443522 RGD:8548549 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO protein: altered activity: eye
protein:increased expression:retina:		 RGD PMID:19484445 PMID:23648097 RGD:5686431, RGD:10046025 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:10366744 RGD:10047417 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 ISO RGD PMID:20216911 RGD:2326035 NCBI chr 1:160,037,467...160,070,160
Ensembl chr 1:159,998,651...160,070,483 		JBrowse link
G MT-CO1 mitochondrially encoded cytochrome c oxidase I ISO mRNA:increased expression:retina RGD PMID:12076086 RGD:8662362 NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445 		JBrowse link
G MYRF myelin regulatory factor ISO mRNA:decreased expression: oligodendrocyte RGD PMID:29915135 RGD:213230153 NCBI chr11:61,752,636...61,788,518
Ensembl chr11:61,752,636...61,788,518 		JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase treatment ISO RGD PMID:28032230 RGD:13781885 NCBI chr 7:106,248,298...106,285,888
Ensembl chr 7:106,248,298...106,285,966 		JBrowse link
G NCAM1 neural cell adhesion molecule 1 ISO RGD PMID:18757519 RGD:2326023 NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,275...113,278,436 		JBrowse link
G NEFM neurofilament medium chain ISO RGD PMID:8501527 RGD:9743936 NCBI chr 8:24,913,761...24,919,093
Ensembl chr 8:24,913,758...24,919,098 		JBrowse link
G NEO1 neogenin 1 ISO protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chr15:73,051,692...73,305,206
Ensembl chr15:73,051,710...73,305,205 		JBrowse link
G NGF nerve growth factor ISO protein:increased expression:retina RGD PMID:28067793 RGD:402463954 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NGFR nerve growth factor receptor ISO RGD PMID:20943663 RGD:5508695 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008 		JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 ISO RGD PMID:20943663 RGD:5508695 NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,636...156,881,850 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 treatment ISO RGD PMID:20357199 PMID:34245756 RGD:5684908, RGD:597015764 NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751 		JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO mRNA:increased expression:retina: RGD PMID:12836167 RGD:1299297 NCBI chr12:79,584,879...79,690,964
Ensembl chr12:79,574,979...79,690,964 		JBrowse link
G PAX6 paired box 6 ISO protein:increased expression:retina (rat) RGD PMID:23297010 RGD:8552379 NCBI chr11:31,789,026...31,817,961
Ensembl chr11:31,784,779...31,817,961 		JBrowse link
G PDGFB platelet derived growth factor subunit B ISO protein:decreased expression:nerve fiber: RGD PMID:9893812 RGD:10449496 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO protein:increased expression:optic nerve (rat) RGD PMID:22336118 RGD:6767293 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
G PLAU plasminogen activator, urokinase ISO mRNA:increased expression:optic nerve (rat) RGD PMID:20798533 RGD:6483802 NCBI chr10:73,909,164...73,917,494
Ensembl chr10:73,909,177...73,917,496 		JBrowse link
G PTPN5 protein tyrosine phosphatase non-receptor type 5 ISO protein:increased expression:retina (rat) RGD PMID:15555919 RGD:9835027 NCBI chr11:18,727,928...18,792,721
Ensembl chr11:18,727,928...18,792,721 		JBrowse link
G RHOA ras homolog family member A ISO protein:increased expression, altered localization:retina RGD PMID:17534117 RGD:1642826 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G SNW1 SNW domain containing 1 ISO protein:increased expression:retina (rat) RGD PMID:25074585 RGD:11035254 NCBI chr14:77,717,599...77,761,156
Ensembl chr14:77,717,599...77,761,207 		JBrowse link
G TLR2 toll like receptor 2 treatment ISO RGD PMID:19661221 RGD:597538516 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR4 toll like receptor 4 ISO protein:increased expression:optic nerve RGD PMID:23103505 RGD:7794777 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO RGD PMID:18552980 PMID:14697498 RGD:7794683, RGD:8661743 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TRADD TNFRSF1A associated via death domain ISO protein:increased expression: retina RGD PMID:18552980 RGD:7794683 NCBI chr16:67,154,185...67,159,909
Ensembl chr16:67,154,185...67,159,909 		JBrowse link
G YBX3 Y-box binding protein 3 ISO mRNA:increased expression:retinal ganglion cell RGD PMID:11750989 RGD:2311250 NCBI chr12:10,699,089...10,723,323
Ensembl chr12:10,699,089...10,723,323 		JBrowse link
Penetrating Eye Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF2 fibroblast growth factor 2 ISO mRNA:increased expression:retina RGD PMID:9268592 RGD:8655567 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G NEO1 neogenin 1 ISO protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chr15:73,051,692...73,305,206
Ensembl chr15:73,051,710...73,305,205 		JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a ISO protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chr15:93,035,271...93,089,211
Ensembl chr15:93,035,271...93,089,211 		JBrowse link
Penetrating Head Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO protein:increased expression,increased activity:cerebral cortex: RGD PMID:16672190 RGD:9685448 NCBI chr10:95,694,186...95,877,266
Ensembl chr10:95,711,779...95,877,266 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO mRNA,protein:increased expression:astrocyte,macrophage,neutrophil: RGD PMID:11168551 RGD:10402049 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834 		JBrowse link
G GFAP glial fibrillary acidic protein ISO RGD PMID:10225952 RGD:6480471 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G PDGFB platelet derived growth factor subunit B ISO protein:increased expression:neuron: RGD PMID:7526956 RGD:10449485 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
G VIM vimentin ISO RGD PMID:10225952 RGD:6480471 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
Post-Head Injury Coma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRH thyrotropin releasing hormone EXP CTD Direct Evidence: therapeutic CTD PMID:8690305 NCBI chr 3:129,974,720...129,977,935
Ensembl chr 3:129,974,688...129,977,935 		JBrowse link
Skull Fractures term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 treatment IDA RGD PMID:16332232 RGD:8699514 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761 		JBrowse link
G IGF1 insulin like growth factor 1 IEP protein:decreased expression:serum: RGD PMID:12002507 RGD:8548865 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
Subdural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLAT plasminogen activator, tissue type EXP CTD Direct Evidence: marker/mechanism CTD PMID:1899364 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
traumatic brain injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM10 ADAM metallopeptidase domain 10 ISO RGD PMID:22489706 RGD:13703033 NCBI chr15:58,588,809...58,749,707
Ensembl chr15:58,588,809...58,749,791 		JBrowse link
G AHR aryl hydrocarbon receptor ISO protein:increased expression:T cell, neuron, brain cortex, hippocampus RGD PMID:27506546 RGD:405878081 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G APP amyloid beta precursor protein treatment IDA RGD PMID:29320530 RGD:13782048 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO RGD PMID:24582457 RGD:13782254 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G BDNF brain derived neurotrophic factor ISO mRNA:increased expression:CA3 field of hippocampus, dentate gyrus RGD PMID:10925157 RGD:596936229 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058 		JBrowse link
G BID BH3 interacting domain death agonist disease_progression
severity		 ISO RGD PMID:12172380 PMID:15307896 RGD:632018, RGD:5509821 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G CAPN1 calpain 1 severity ISO protein:increased expression:cytosol, plasma membrane RGD PMID:9469158 PMID:15307896 RGD:13792664, RGD:5509821 NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006 		JBrowse link
G CAPN2 calpain 2 severity ISO RGD PMID:9469158 PMID:15307896 RGD:13792664, RGD:5509821 NCBI chr 1:223,701,597...223,776,018
Ensembl chr 1:223,701,593...223,776,018 		JBrowse link
G CASP3 caspase 3 severity ISO protein:increased expression:cerebral cortex RGD PMID:27614125 PMID:15307896 RGD:329961568, RGD:5509821 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 disease_progression
severity		 ISO RGD PMID:12172380 PMID:15307896 RGD:632018, RGD:5509821 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 disease_progression
severity		 ISO RGD PMID:12172380 PMID:15307896 RGD:632018, RGD:5509821 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CCNG1 cyclin G1 treatment ISO RGD PMID:24398934 PMID:18612315 RGD:151356934, RGD:151356935 NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,448,199 		JBrowse link
G CD163 CD163 molecule ISO protein:increased expression:brain, macrophage (rat) RGD PMID:22583855 RGD:127285798 NCBI chr12:7,470,811...7,503,777
Ensembl chr12:7,470,811...7,503,893 		JBrowse link
G CD8A CD8 subunit alpha ISO mRNA:increased expression:brain (mouse) RGD PMID:31383034 RGD:124715446 NCBI chr 2:86,784,605...86,808,396
Ensembl chr 2:86,784,610...86,808,396 		JBrowse link
G CIT citron rho-interacting serine/threonine kinase ISO mRNA:decreased expression:cerebral cortex��(rat) RGD PMID:12503083 RGD:2317873 NCBI chr12:119,685,791...119,877,320
Ensembl chr12:119,685,791...119,877,320 		JBrowse link
G CTNNB1 catenin beta 1 treatment ISO RGD PMID:26296359 RGD:597538582 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 treatment ISO RGD PMID:26435412 RGD:27095897 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 ISO protein:increased expression:cerebral cortex RGD PMID:27614125 RGD:329961568 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene) treatment ISO RGD PMID:26068867 RGD:401901590 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865 		JBrowse link
G DRD1 dopamine receptor D1 treatment ISO RGD PMID:24047867 RGD:13506948 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182 		JBrowse link
G DRD2 dopamine receptor D2 treatment ISO RGD PMID:24047867 RGD:13506948 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase ISO mRNA:decreased expression:cerebral cortex RGD PMID:31992337 RGD:329901857 NCBI chr16:53,703,963...54,121,941
Ensembl chr16:53,701,692...54,158,512 		JBrowse link
G FUBP1 far upstream element binding protein 1 ISO RGD PMID:23797733 RGD:13673879 NCBI chr 1:77,944,055...77,979,501
Ensembl chr 1:77,944,055...77,979,110 		JBrowse link
G GNAL G protein subunit alpha L ISO RGD PMID:29215295 RGD:13513923 NCBI chr18:11,689,264...11,885,685
Ensembl chr18:11,689,264...11,885,685 		JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 ISO protein:increased phosphorylation:central amygdaloid nucleus (rat) RGD PMID:30638118 RGD:405101698 NCBI chr 5:153,489,615...153,813,869
Ensembl chr 5:153,489,615...153,813,869 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IL1B interleukin 1 beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G ITGB1 integrin subunit beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G LAMA1 laminin subunit alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr18:6,941,742...7,117,797
Ensembl chr18:6,941,742...7,117,797 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 ISO protein:increased expression:hippocampus: RGD PMID:28365875 RGD:13703062 NCBI chr  X:120,426,148...120,469,349
Ensembl chr  X:120,426,148...120,469,365 		JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:31539545 RGD:126781751 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G MAPT microtubule associated protein tau treatment ISO RGD PMID:28412141 PMID:25771151 PMID:26484783 PMID:26729399 RGD:13800902, RGD:13800917, RGD:13800912, RGD:13800909 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334 		JBrowse link
G METTL14 methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit ISO mRNA:decreased expression:cerebral cortex RGD PMID:31992337 RGD:329901857 NCBI chr 4:118,685,392...118,715,430
Ensembl chr 4:118,685,392...118,715,433 		JBrowse link
G MIR155 microRNA 155 ISO RGD PMID:28804446 RGD:25314324 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MMP2 matrix metallopeptidase 2 ISO protein:increased expression:cerebral cortex RGD PMID:27614125 RGD:329961568 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPO myeloperoxidase EXP CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G NCSTN nicastrin ISO RGD PMID:18240300 RGD:13801189 NCBI chr 1:160,343,383...160,358,949
Ensembl chr 1:160,343,294...160,358,952 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO protein:increased expression:brain: RGD PMID:30855558 RGD:26884463 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NGF nerve growth factor treatment ISO RGD PMID:26285082 RGD:402463964 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NMNAT1 nicotinamide nucleotide adenylyltransferase 1 EXP CTD Direct Evidence: therapeutic CTD PMID:27822499 NCBI chr 1:9,942,923...9,996,892
Ensembl chr 1:9,943,428...9,985,501 		JBrowse link
G NOS2 nitric oxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOX1 NADPH oxidase 1 ISO protein:increased expression:cerebral cortex RGD PMID:27614125 RGD:329961568 NCBI chr  X:100,843,324...100,874,359
Ensembl chr  X:100,843,324...100,874,359 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO protein:increased phosphorylation:amygdala
mRNA:decreased expression:hippocampus, hypothalamus		 RGD PMID:30638118 PMID:36637480 RGD:405101698, RGD:408364984 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO mRNA:increased expression:dentate gyrus RGD PMID:10925157 RGD:596936229 NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751 		JBrowse link
G OCLN occludin EXP CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15829224 PMID:28642177 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PDE10A phosphodiesterase 10A ISO RGD PMID:29215295 RGD:13513923 NCBI chr 6:165,327,289...165,988,052
Ensembl chr 6:165,327,287...165,988,117 		JBrowse link
G PDYN prodynorphin ISO mRNA:increased expression:hippocampus RGD PMID:12626770 RGD:633616 NCBI chr20:1,978,756...1,994,285
Ensembl chr20:1,978,757...1,994,285 		JBrowse link
G PHACTR1 phosphatase and actin regulator 1 treatment ISO RGD PMID:36571365 RGD:401901253 NCBI chr 6:12,716,767...13,287,837
Ensembl chr 6:12,716,312...13,290,446 		JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha ISO RGD PMID:20713027 RGD:13830881 NCBI chr 2:68,178,857...68,252,532
Ensembl chr 2:68,178,857...68,256,237 		JBrowse link
G PPP3R2 protein phosphatase 3 regulatory subunit B, beta ISO RGD PMID:20713027 RGD:13830881 NCBI chr 9:101,591,604...101,594,969
Ensembl chr 9:101,591,604...101,595,021 		JBrowse link
G PSEN1 presenilin 1 ISO RGD PMID:18240300 RGD:13801189 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:25668593 PMID:28642177 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SOX2 SRY-box transcription factor 2 treatment ISO RGD PMID:26296359 RGD:597538582 NCBI chr 3:181,711,925...181,714,436
Ensembl chr 3:181,711,925...181,714,436 		JBrowse link
G TGFB1 transforming growth factor beta 1 treatment ISO RGD PMID:28433746 RGD:14995478 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 treatment ISO RGD PMID:27553877 RGD:14995939 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G UBE4B ubiquitination factor E4B EXP CTD Direct Evidence: therapeutic CTD PMID:27822499 NCBI chr 1:10,032,958...10,181,239
Ensembl chr 1:10,032,832...10,181,239 		JBrowse link
G WNT3A Wnt family member 3A treatment ISO RGD PMID:26296359 RGD:597538582 NCBI chr 1:228,006,998...228,061,271
Ensembl chr 1:228,006,998...228,061,271 		JBrowse link
Traumatic Intracranial Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F7 coagulation factor VII EXP CTD Direct Evidence: therapeutic CTD PMID:20370756 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685 		JBrowse link
Traumatic Subarachnoid Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 treatment ISO RGD PMID:18854840 RGD:2325137 NCBI chr11:17,392,498...17,476,845
Ensembl chr11:17,392,498...17,476,894 		JBrowse link
Trigeminal Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 ISO RGD PMID:22977862 RGD:8547771 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
Vestibulocochlear Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 ISO mRNA:increased expression:Vestibulocochlear nerve: RGD PMID:22178544 RGD:8548530 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 121159
    Wounds and Injuries 1676
      Nervous System Trauma 649
        Craniocerebral Trauma 381
          Brain Injuries + 304
          Cerebrospinal Fluid Leak + 0
          Closed Head Injuries + 13
          Cranial Nerve Injuries + 82
          Facial Injuries + 15
          Penetrating Head Injuries 5
          Post-Head Injury Coma 1
          Skull Fractures + 4
          Traumatic Intracranial Hemorrhage + 8
Path 2
Term Annotations click to browse term
  disease 121159
    disease of anatomical entity 111930
      nervous system disease 58665
        Nervous System Trauma 649
          Craniocerebral Trauma 381
            Brain Injuries + 304
            Cerebrospinal Fluid Leak + 0
            Closed Head Injuries + 13
            Cranial Nerve Injuries + 82
            Facial Injuries + 15
            Penetrating Head Injuries 5
            Post-Head Injury Coma 1
            Skull Fractures + 4
            Traumatic Intracranial Hemorrhage + 8
paths to the root