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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Craniocerebral Trauma
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Accession:DOID:9007621 term browser browse the term
Definition:Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage.
Synonyms:exact_synonym: Craniocerebral Injuries;   Craniocerebral Injury;   Craniocerebral Traumas;   Crushing Skull Injuries;   Crushing Skull Injury;   Forehead Trauma;   Forehead Traumas;   Frontal Region Trauma;   Frontal Region Traumas;   Head Injuries;   Head Injury;   Head Trauma;   Head Traumas;   Minor Head Injuries;   Minor Head Injury;   Multiple Head Injuries;   Multiple Head Injury;   Occipital Region Trauma;   Occipital Region Traumas;   Occipital Trauma;   Occipital Traumas;   Open Head Injuries;   Open Head Injury;   Parietal Region Trauma;   Parietal Region Traumas;   Superficial Head Injuries;   Superficial Head Injury;   Temporal Region Trauma;   Temporal Region Traumas
 primary_id: MESH:D006259;   RDO:0005059
 xref: EFO:0009505


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Craniocerebral Trauma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADNP activity dependent neuroprotector homeobox ISO RGD PMID:11123362 RGD:2312784 NCBI chr24:37,211,776...37,245,938
Ensembl chr24:37,213,942...37,243,702 		JBrowse link
G IL1A interleukin 1 alpha ISO protein:increased expression:microglial cell RGD PMID:7830934 RGD:10045949 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435 		JBrowse link
G POSTN periostin ISO RGD PMID:17878602 RGD:10041014 NCBI chr25:3,167,319...3,208,970
Ensembl chr25:3,167,359...3,208,411 		JBrowse link
G SERPINC1 serpin family C member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8810955 NCBI chr 7:25,322,668...25,333,022
Ensembl chr 7:25,316,129...25,332,987 		JBrowse link
Acute Subdural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPO erythropoietin treatment ISO RGD PMID:23415790 RGD:10401075 NCBI chr 6:8,994,211...8,995,954
Ensembl chr 6:8,994,211...8,996,144 		JBrowse link
G F7 coagulation factor VII ISO CTD Direct Evidence: therapeutic CTD PMID:12503044 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 treatment ISO RGD PMID:15379997 RGD:329969897 NCBI chr 1:111,391,464...111,407,612
Ensembl chr 1:111,391,159...111,407,701 		JBrowse link
brain compression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFL1 cofilin 1 treatment ISO RGD PMID:25708984 RGD:12738361 NCBI chr18:51,404,649...51,408,240
Ensembl chr18:51,401,659...51,408,212 		JBrowse link
Brain Concussion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 ISO RGD PMID:26448536 RGD:13506960 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241 		JBrowse link
G DRD3 dopamine receptor D3 ISO RGD PMID:26448536 RGD:13506960 NCBI chr33:18,369,362...18,414,465
Ensembl chr33:18,372,865...18,412,277 		JBrowse link
G DRD4 dopamine receptor D4 ISO RGD PMID:26448536 RGD:13506960
G IL6 interleukin 6 treatment ISO RGD PMID:27113205 RGD:11062140 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
Brain Contusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 ameliorates ISO RGD PMID:31654641 RGD:408418727 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761 		JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:28140659 RGD:13782305 NCBI chr16:45,920,074...45,940,507
Ensembl chr16:45,920,071...45,940,505 		JBrowse link
G CASP8 caspase 8 treatment ISO RGD PMID:28140659 RGD:13782305 NCBI chr37:10,362,071...10,402,108
Ensembl chr37:10,391,048...10,401,822 		JBrowse link
G IL1B interleukin 1 beta treatment ISO RGD PMID:31654641 RGD:408418727 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G PYCARD PYD and CARD domain containing treatment ISO RGD PMID:19401709 RGD:5491174 NCBI chr 6:17,049,352...17,051,348
Ensembl chr 6:17,049,705...17,051,240 		JBrowse link
G TNF tumor necrosis factor treatment ISO RGD PMID:31654641 RGD:408418727 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425 		JBrowse link
Brain Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 treatment ISO RGD PMID:21107131 RGD:12791995 NCBI chr21:39,963,001...40,037,040
Ensembl chr21:39,962,947...40,036,981 		JBrowse link
G ACAN aggrecan ISO mRNA:increased expression:fascia dentata (rat) RGD PMID:18511192 RGD:2315807 NCBI chr 3:51,995,100...52,031,812
Ensembl chr 3:51,969,779...52,031,544 		JBrowse link
G ACTR2 actin related protein 2 ISO mRNA, protein:decreased expression:hippocampus (rat) RGD PMID:22120305 RGD:11530046 NCBI chr10:64,696,068...64,733,027
Ensembl chr10:64,696,111...64,730,553 		JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 ISO RGD PMID:16689670 RGD:2325298 NCBI chr 7:67,682,421...67,691,035 JBrowse link
G ADRA1A adrenoceptor alpha 1A ISO mRNA:increased expression:frontal cortex RGD PMID:20974230 RGD:5688366 NCBI chr25:30,690,959...30,801,484
Ensembl chr25:30,693,571...30,801,486 		JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO protein:increased expression:brain (rat) RGD PMID:22491548 PMID:22915134 PMID:24859607 RGD:7245513 RGD:7245557 RGD:8696001 NCBI chr12:1,574,251...1,577,410
Ensembl chr12:1,574,251...1,577,129 		JBrowse link
G AIF1 allograft inflammatory factor 1 ISO protein:increased expression:cerebral cortex (rat) RGD PMID:19520144 RGD:2313020 NCBI chr12:1,104,350...1,106,179
Ensembl chr12:1,104,394...1,106,177 		JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 ISO protein:increased expression:nucleus: RGD PMID:12091479 RGD:10053567 NCBI chr  X:101,275,027...101,307,551
Ensembl chr  X:101,275,017...101,307,367 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO protein:increased phosphorylation:brain, neuron RGD PMID:16234845 RGD:5509090 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G ALB albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:7909931 PMID:17188501 NCBI chr13:62,133,747...62,169,349
Ensembl chr13:62,053,814...62,294,709 		JBrowse link
G AMBP alpha-1-microglobulin/bikunin precursor ISO protein:increased expression:urine RGD PMID:14592616 RGD:6904155 NCBI chr11:68,338,644...68,353,366
Ensembl chr11:68,338,389...68,351,994 		JBrowse link
G ANK3 ankyrin 3 ISO RGD PMID:20557305 RGD:6767288 NCBI chr 4:12,166,275...12,827,175
Ensembl chr 4:12,167,550...12,827,037 		JBrowse link
G ANP32A acidic nuclear phosphoprotein 32 family member A ISO RGD PMID:24385964 RGD:10401136 NCBI chr30:32,741,582...32,778,883
Ensembl chr30:32,741,582...32,798,188 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 ISO protein:increased expression:cerebral cortex RGD PMID:11567033 RGD:2325751 NCBI chr15:38,026,893...38,160,842
Ensembl chr15:38,028,132...38,114,987 		JBrowse link
G APBB1 amyloid beta precursor protein binding family B member 1 ISO mRNA:increased expression:brain RGD PMID:12707777 RGD:2301208 NCBI chr21:29,719,386...29,741,658
Ensembl chr21:29,719,589...29,759,046 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11447995 NCBI chr15:17,786,808...17,789,422
Ensembl chr15:17,786,357...17,789,422 		JBrowse link
G APOD apolipoprotein D ISO mRNA, protein:increased expression:cerebral cortex, glia cell, neuron RGD PMID:10501208 RGD:2311202 NCBI chr33:30,490,149...30,504,804
Ensembl chr33:30,488,135...30,509,289 		JBrowse link
G APP amyloid beta precursor protein ISO protein:increased expression:hippocampus RGD PMID:16300758 RGD:10054281 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337 		JBrowse link
G AQP4 aquaporin 4 ISO protein:increased expression:cerebral cortex RGD PMID:21083433 PMID:21488209 RGD:5148014 RGD:5148034 NCBI chr 7:61,855,617...61,868,953
Ensembl chr 7:61,855,744...61,865,089 		JBrowse link
G ASIC1 acid sensing ion channel subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21307247 NCBI chr27:4,638,826...4,663,352
Ensembl chr27:4,638,812...4,648,038 		JBrowse link
G ASTN1 astrotactin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14499481 NCBI chr 7:22,455,117...22,752,044
Ensembl chr 7:22,455,499...22,757,029 		JBrowse link
G ATG12 autophagy related 12 ISO protein:altered localization:brain RGD PMID:18059433 RGD:2301217 NCBI chr11:5,531,062...5,543,034
Ensembl chr11:5,531,759...5,542,743 		JBrowse link
G AVPR1A arginine vasopressin receptor 1A ISO mRNA:increased expression:cerebral cortex RGD PMID:17244947 RGD:2300372 NCBI chr10:6,266,217...6,269,662
Ensembl chr10:6,265,998...6,269,662 		JBrowse link
G BAD BCL2 associated agonist of cell death ISO mRNA, protein:increased expression:cerebral cortex RGD PMID:15941375 RGD:2292694 NCBI chr18:52,781,335...52,791,789
Ensembl chr18:52,781,921...52,791,405 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:20888848 RGD:10054247 NCBI chr 1:107,423,388...107,426,464
Ensembl chr 1:107,422,424...107,426,464 		JBrowse link
G BCAT1 branched chain amino acid transaminase 1 ISO Protein:increased expression:neurons RGD PMID:10686349 RGD:631308 NCBI chr27:22,536,297...22,643,350
Ensembl chr27:22,535,254...22,636,959 		JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:18093155 PMID:20888848 RGD:10054247 RGD:2293059 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658 		JBrowse link
G BDNF brain derived neurotrophic factor ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:15500971 PMID:20544832 PMID:21269288 RGD:4891136 NCBI chr21:48,191,580...48,243,699
Ensembl chr21:48,192,670...48,204,480 		JBrowse link
G BECN1 beclin 1 ISO protein:increased expression:hippocampus
CTD Direct Evidence: therapeutic
protein:increased expression:neuron, astrocyte
protein:increased expression:brain		 RGD
CTD		 PMID:16874043 PMID:18500386 PMID:24221859 PMID:34929507 RGD:11558018 RGD:6483098 RGD:6483314 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ISO mRNA, protein:increased expression:brain, astrocyte, neuron RGD PMID:15453988 RGD:2293136 NCBI chr 9:2,930,308...2,959,307 JBrowse link
G BMP6 bone morphogenetic protein 6 ISO protein:increased expression:brain, astrocyte, neuron RGD PMID:16388909 RGD:2289020 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 ISO mRNA:increased expression:dentate gyrus, neuron RGD PMID:9080432 RGD:5129488 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024 		JBrowse link
G BYSL bystin like ISO mRNA, protein:increased expression:substantia nigra, striatum (rat) RGD PMID:15305856 RGD:2316201 NCBI chr12:10,580,881...10,592,313
Ensembl chr12:10,581,217...10,591,923 		JBrowse link
G C1QA complement C1q A chain ISO RGD PMID:23808389 RGD:10054313 NCBI chr 2:76,668,086...76,671,082
Ensembl chr 2:76,668,217...76,670,977 		JBrowse link
G C3 complement C3 ISO RGD PMID:23808389 RGD:10054313 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761 		JBrowse link
G CASK calcium/calmodulin dependent serine protein kinase ISO RGD PMID:25089700 RGD:11576302 NCBI chr  X:35,939,117...36,296,438
Ensembl chr  X:35,940,647...36,297,014 		JBrowse link
G CASP12 caspase 12 severity ISO mRNA, protein:increased expression, increased activity:cerebral cortex, hippocampus, neuron, astrocyte RGD PMID:14675152 RGD:2311485 NCBI chr 5:27,162,840...27,176,964
Ensembl chr 5:27,161,700...27,177,683 		JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:20888848 RGD:10054247 NCBI chr16:45,920,074...45,940,507
Ensembl chr16:45,920,071...45,940,505 		JBrowse link
G CASP8 caspase 8 ISO protein:altered localization RGD PMID:15590916 RGD:1624191 NCBI chr37:10,362,071...10,402,108
Ensembl chr37:10,391,048...10,401,822 		JBrowse link
G CAST calpastatin severity ISO mRNA:increased expression:cerebral cortex RGD PMID:15307896 RGD:5509821 NCBI chr 3:12,920,514...13,031,974
Ensembl chr 3:12,922,453...13,031,959 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:brain, neuron		 CTD
RGD		 PMID:11113322 PMID:19210118 PMID:21549006 RGD:2306999 RGD:9587789 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CCL20 C-C motif chemokine ligand 20 treatment ISO RGD PMID:22040257 RGD:7483630 NCBI chr25:40,506,385...40,509,903
Ensembl chr25:40,506,753...40,509,709 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO mRNA:increased expression:hippocampus RGD PMID:24344922 RGD:8552265 NCBI chr20:42,293,288...42,297,952
Ensembl chr20:42,294,996...42,297,952 		JBrowse link
G CD14 CD14 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 2:35,790,505...35,792,967 JBrowse link
G CD40 CD40 molecule treatment ISO RGD PMID:23924471 RGD:7248749 NCBI chr24:33,352,992...33,383,488
Ensembl chr24:33,372,930...33,383,301 		JBrowse link
G CD40LG CD40 ligand treatment ISO RGD PMID:11755016 PMID:25972624 RGD:11344972 RGD:8547803 NCBI chr  X:107,001,421...107,023,007
Ensembl chr  X:107,010,890...107,023,006 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO protein:increased expression:nucleus: RGD PMID:9914434 RGD:8662346 NCBI chr12:5,746,898...5,755,103
Ensembl chr12:5,745,852...5,892,281 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO protein:decreased expression:cerebral cortex RGD PMID:21728064 RGD:10045359 NCBI chr27:33,609,154...33,613,558
Ensembl chr27:33,611,760...33,612,906 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha ISO mRNA, protein:increased expression:cerebral cortex (mouse) RGD PMID:19833158 RGD:10401206 NCBI chr 1:118,846,252...118,851,045 JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO mRNA, protein:increased expression:cerebral cortex (mouse)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:19833158 PMID:21549006 RGD:10401206 NCBI chr24:36,661,294...36,663,162
Ensembl chr24:36,661,616...36,662,656 		JBrowse link
G CES1 carboxylesterase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 2:60,276,723...60,305,970
Ensembl chr 2:60,236,150...60,321,178 		JBrowse link
G CFB complement factor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17474994 NCBI chr12:1,400,143...1,406,267 JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr16:11,515,727...11,665,651
Ensembl chr16:11,515,426...11,664,977 		JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 3:36,852,082...37,164,930
Ensembl chr 3:36,852,543...36,978,399 		JBrowse link
G CNP 2',3'-cyclic nucleotide 3' phosphodiesterase ISO protein:increased expression:hippocampus RGD PMID:20215974 RGD:6483336 NCBI chr 9:20,888,350...20,896,139
Ensembl chr 9:20,886,574...20,896,079 		JBrowse link
G COMT catechol-O-methyltransferase ISO protein:increased expression:hippocampus RGD PMID:17240060 RGD:2289740 NCBI chr26:29,359,930...29,381,854
Ensembl chr26:29,360,356...29,366,008 		JBrowse link
G CRP C-reactive protein disease_progression ISO RGD PMID:24456846 RGD:9585646 NCBI chr38:22,396,787...22,398,180
Ensembl chr38:22,396,263...22,399,166 		JBrowse link
G CSF2 colony stimulating factor 2 disease_progression ISO RGD PMID:21515263 RGD:5686795 NCBI chr11:20,342,880...20,346,959
Ensembl chr11:20,344,648...20,346,959 		JBrowse link
G CSF3 colony stimulating factor 3 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:21549006 PMID:24239694 RGD:11039431 NCBI chr 9:22,529,643...22,532,326
Ensembl chr 9:22,530,698...22,533,108 		JBrowse link
G CSPG4 chondroitin sulfate proteoglycan 4 ISO protein:altered expression:cerebral cortex RGD PMID:19473238 RGD:5686860 NCBI chr30:38,465,486...38,498,365
Ensembl chr30:38,465,241...38,497,971 		JBrowse link
G CUL5 cullin 5 ISO mRNA, protein:decreased expression:cerebral cortex, hippocampus RGD PMID:17010517 RGD:2301432 NCBI chr 5:24,393,692...24,477,595
Ensembl chr 5:24,396,823...24,488,043 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr32:598,406...599,925
Ensembl chr32:597,987...599,979 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO mRNA:increased expression:hindbrain RGD PMID:16329132 RGD:1599699 NCBI chr30:37,474,997...37,487,028
Ensembl chr30:37,473,901...37,487,507 		JBrowse link
G DAB2 DAB adaptor protein 2 ISO RGD PMID:15774263 RGD:7243841 NCBI chr 4:69,625,874...69,648,349
Ensembl chr 4:69,625,527...69,648,321 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:19429151 RGD:9588608 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029 		JBrowse link
G DPYSL2 dihydropyrimidinase like 2 ISO protein:increased degradation:cerebral cortex, hippocampus RGD PMID:17402852 RGD:2303056 NCBI chr25:30,900,347...31,038,256
Ensembl chr25:30,903,253...31,038,144 		JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:18509630 RGD:2311580 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241 		JBrowse link
G DUSP5 dual specificity phosphatase 5 ISO mRNA:increased expression:cerebral cortex RGD PMID:12503083 RGD:2317873 NCBI chr28:21,829,891...21,844,590
Ensembl chr28:21,829,921...21,841,454 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha ISO RGD PMID:11526986 RGD:10395358 NCBI chr 8:41,354,400...41,371,676
Ensembl chr 8:41,351,244...41,371,056 		JBrowse link
G ELK1 ETS transcription factor ELK1 ISO RGD PMID:15362724 RGD:7488910 NCBI chr  X:41,256,205...41,270,656
Ensembl chr  X:41,257,482...41,270,776 		JBrowse link
G ENO2 enolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34533065 NCBI chr27:38,120,404...38,128,543
Ensembl chr27:38,119,413...38,129,182 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 treatment ISO RGD PMID:22960363 RGD:10395371 NCBI chr10:48,550,836...48,636,776
Ensembl chr10:48,551,410...48,634,844 		JBrowse link
G EPHA4 EPH receptor A4 ISO protein:increased expression, increased activity:astrocyte RGD PMID:22318127 RGD:5688763 NCBI chr37:27,670,143...27,809,642
Ensembl chr37:27,677,566...27,809,646 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO RGD PMID:21075124 RGD:5688356 NCBI chr25:30,045,040...30,107,110
Ensembl chr25:30,045,291...30,107,110 		JBrowse link
G EPO erythropoietin treatment ISO CTD Direct Evidence: therapeutic
mRNA:increased expression:brain:		 CTD
RGD		 PMID:18093155 PMID:20833152 PMID:23063952 RGD:10401061 RGD:2293059 NCBI chr 6:8,994,211...8,995,954
Ensembl chr 6:8,994,211...8,996,144 		JBrowse link
G EPOR erythropoietin receptor ISO mRNA:increased expression:brain: RGD PMID:18093155 RGD:2293059 NCBI chr20:49,945,777...49,950,856
Ensembl chr20:49,945,777...49,950,856 		JBrowse link
G F2 coagulation factor II, thrombin severity ISO RGD PMID:21355766 RGD:5147766 NCBI chr18:42,782,744...42,799,531
Ensembl chr18:42,782,751...42,799,459 		JBrowse link
G FAS Fas cell surface death receptor ISO associated with Hyperoxia
mRNA:increased expression:hippocampus		 RGD PMID:16078565 PMID:19107989 RGD:1600354 RGD:8662854 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321 		JBrowse link
G FGF2 fibroblast growth factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:21269288 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151 		JBrowse link
G FMR1 Fragile X messenger ribonucleoprotein 1 ISO protein:altered localization:hippocampus (rat) RGD PMID:16510718 RGD:11667962 NCBI chr  X:116,249,079...116,287,008
Ensembl chr  X:116,249,142...116,321,439 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:9630518 NCBI chr 8:48,330,856...48,334,273
Ensembl chr 8:48,331,026...48,333,467 		JBrowse link
G FOXP1 forkhead box P1 treatment ISO RGD PMID:26842647 RGD:11561903 NCBI chr20:20,438,631...21,020,516
Ensembl chr20:20,788,433...21,016,397 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase ISO protein:decreased expression:hippocampus RGD PMID:18501200 RGD:2307353 NCBI chr  X:122,217,317...122,231,862
Ensembl chr  X:122,205,683...122,231,678 		JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 3:33,878,948...34,101,987
Ensembl chr 3:33,878,904...34,097,764 		JBrowse link
G GABRG3 gamma-aminobutyric acid type A receptor subunit gamma3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 3:32,956,061...33,641,971
Ensembl chr 3:32,964,122...33,642,686 		JBrowse link
G GDNF glial cell derived neurotrophic factor ISO mRNA:increased expression:brain RGD PMID:18501516 RGD:2324932 NCBI chr 4:70,966,694...70,991,860
Ensembl chr 4:70,971,432...70,989,714 		JBrowse link
G GJA1 gap junction protein alpha 1 treatment ISO RGD PMID:23485053 RGD:8662424 NCBI chr 1:60,941,772...60,944,694
Ensembl chr 1:60,929,097...60,942,936 		JBrowse link
G GJA5 gap junction protein alpha 5 ISO protein:increased expression:cerebral artery RGD PMID:21895483 RGD:7207391 NCBI chr17:58,289,327...58,305,315
Ensembl chr17:58,289,327...58,305,315 		JBrowse link
G GPX1 glutathione peroxidase 1 ISO mRNA:decreased expression:hippocampus, neuron RGD PMID:15791111 RGD:2306624 NCBI chr20:39,889,165...39,890,253
Ensembl chr20:39,889,174...39,890,260 		JBrowse link
G GRM8 glutamate metabotropic receptor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr14:8,982,180...9,719,813
Ensembl chr14:8,983,802...9,719,357 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:22643085 PMID:24675465 RGD:10045646 NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666 		JBrowse link
G GSN gelsolin ISO RGD PMID:14588109 RGD:1599864 NCBI chr11:74,248,227...74,268,129
Ensembl chr11:74,233,457...74,268,129 		JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO mRNA,protein:decreased expression:hippocampus: RGD PMID:11726545 RGD:9686434 NCBI chr 4:64,777,069...65,162,603
Ensembl chr 4:64,775,577...65,160,444 		JBrowse link
G HMGB1 high mobility group box 1 treatment ISO RGD PMID:22915134 RGD:7245513 NCBI chr25:9,431,223...9,558,167
Ensembl chr25:9,431,218...9,558,165 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:18562561 RGD:5508455 NCBI chr 3:30,970,037...30,988,987
Ensembl chr 3:30,970,037...30,990,294 		JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:23470432 RGD:10755702 NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773 		JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO protein:increased expression:cerebral white matter (rat) RGD PMID:22067617 RGD:5688785 NCBI chr11:21,290,603...21,363,701
Ensembl chr11:21,290,621...21,505,122 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO RGD PMID:11746764 RGD:6480530 NCBI chr 6:7,487,164...7,488,576
Ensembl chr 6:7,487,250...7,488,576 		JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO RGD PMID:22465320 RGD:6482178 NCBI chr28:5,438,872...5,524,385
Ensembl chr28:5,440,388...5,524,191 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:brain: RGD PMID:16230799 RGD:11522716 NCBI chr20:50,818,715...50,827,914
Ensembl chr20:50,818,715...50,827,914 		JBrowse link
G IFNL3 interferon lambda 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883
G IGF1 insulin like growth factor 1 treatment ISO human protein in a rat model RGD PMID:9344566 RGD:12904928 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794 		JBrowse link
G IGF2 insulin like growth factor 2 ISO mRNA:decreased expression:brain RGD PMID:11123717 RGD:5509972 NCBI chr18:46,294,036...46,311,982
Ensembl chr18:46,294,019...46,311,982 		JBrowse link
G IL10 interleukin 10 treatment
severity		 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:21549006 PMID:23075771 PMID:23971414 RGD:7364822 RGD:7364983 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057 		JBrowse link
G IL12RB2 interleukin 12 receptor subunit beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 5:43,197,034...43,269,571
Ensembl chr 5:43,197,034...43,257,594 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr  X:87,747,373...87,776,797
Ensembl chr  X:87,747,373...87,776,798 		JBrowse link
G IL16 interleukin 16 ISO RGD PMID:17983426 RGD:5024939 NCBI chr 3:56,473,485...56,575,504
Ensembl chr 3:56,473,486...56,575,104 		JBrowse link
G IL17RD interleukin 17 receptor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr20:33,240,728...33,306,727
Ensembl chr20:33,240,767...33,303,404 		JBrowse link
G IL18 interleukin 18 severity ISO mRNA, protein:increased expression:brain RGD PMID:17188500 RGD:2315917 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348 		JBrowse link
G IL18R1 interleukin 18 receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr10:40,614,336...40,653,300
Ensembl chr10:40,615,312...40,653,454 		JBrowse link
G IL1A interleukin 1 alpha ISO mRNA, protein:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16024175 PMID:21549006 RGD:2311098 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435 		JBrowse link
G IL1B interleukin 1 beta ISO mRNA, protein:increased expression:brain
protein:increased expression:brain, cerebrospinal fluid
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:cerebral cortex		 RGD
CTD		 PMID:16024175 PMID:17612572 PMID:19800810 PMID:21549006 PMID:22503903 RGD:1626652 RGD:2311098 RGD:6482651 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G IL1R1 interleukin 1 receptor type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr10:40,825,986...40,897,898
Ensembl chr10:40,827,377...40,897,596 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO CTD Direct Evidence: therapeutic CTD PMID:25665855 NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329 		JBrowse link
G IL2 interleukin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394 		JBrowse link
G IL3 interleukin 3 disease_progression ISO protein: increased expression: brain: microdialysis perfusate RGD PMID:20717122 PMID:21515263 RGD:5686795 RGD:5686886 NCBI chr11:20,330,480...20,332,668
Ensembl chr11:20,330,480...20,332,668 		JBrowse link
G IL31RA interleukin 31 receptor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 2:43,113,194...43,198,200
Ensembl chr 2:43,144,071...43,193,293 		JBrowse link
G IL4 interleukin 4 ISO protein:decreased expression:plasma RGD PMID:24519543 RGD:10402802 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534 		JBrowse link
G IL5 interleukin 5 treatment ISO RGD PMID:24530657 PMID:24602693 RGD:11522766 RGD:11522770 NCBI chr11:20,825,469...20,827,269
Ensembl chr11:20,825,469...20,827,269 		JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:cerebrospinal fluid (rat)		 CTD
RGD		 PMID:10027774 PMID:19800810 PMID:21549006 PMID:23159883 RGD:11049549 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G IL7 interleukin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr29:26,384,493...26,422,586
Ensembl chr29:26,384,493...26,422,737 		JBrowse link
G IRF1 interferon regulatory factor 1 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:cerebral cortex		 CTD
RGD		 PMID:12503083 PMID:21549006 RGD:2317873 NCBI chr11:20,773,801...20,781,106
Ensembl chr11:20,760,120...20,781,608 		JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:21596098 RGD:6483023 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 5:50,966,698...50,968,939 JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 ISO RGD PMID:20861444 RGD:8662901 NCBI chr38:22,114,718...22,143,625
Ensembl chr38:22,130,508...22,140,813 		JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:cerebral cortex RGD PMID:19733172 PMID:21307798 RGD:5684382 RGD:5684402 NCBI chr13:47,442,861...47,484,574
Ensembl chr13:47,442,764...47,485,042 		JBrowse link
G LEP leptin ISO RGD PMID:21276361 RGD:5128517 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395 		JBrowse link
G LOC102151342 ATP synthase subunit d, mitochondrial-like treatment ISO RGD PMID:26813465 RGD:13800884 NCBI chr 7:66,856,651...66,857,162 JBrowse link
G LOC477072 serotransferrin ISO RGD PMID:22538758 RGD:7244386 NCBI chr23:30,658,250...30,683,816
Ensembl chr23:30,595,704...30,683,845 		JBrowse link
G LOC611538 C-type lectin domain family 4 member E ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr27:37,561,445...37,568,652
Ensembl chr27:37,563,038...37,568,463 		JBrowse link
G LOC611642 interleukin-9 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 6:40,425,072...40,437,917 JBrowse link
G LSG1 large 60S subunit nuclear export GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14499481 NCBI chr33:31,078,384...31,117,093
Ensembl chr33:31,087,349...31,117,095 		JBrowse link
G LY86 lymphocyte antigen 86 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr35:6,627,744...6,687,170
Ensembl chr35:6,627,598...6,687,166 		JBrowse link
G MAG myelin associated glycoprotein susceptibility ISO RGD PMID:17156367 RGD:9685230 NCBI chr 1:117,288,306...117,301,975
Ensembl chr 1:117,288,343...117,302,386 		JBrowse link
G MAP1B microtubule associated protein 1B ISO protein:increased expression, increased phosphorylation:brain RGD PMID:10906717 RGD:2304029 NCBI chr 2:55,175,000...55,258,160
Ensembl chr 2:55,174,837...55,253,975 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:24221859 RGD:11558018 NCBI chr24:23,672,343...23,673,937
Ensembl chr24:23,633,579...23,673,921 		JBrowse link
G MAP2 microtubule associated protein 2 ISO protein:decreased expression:cerebral cortex, neuron RGD PMID:20568963 PMID:21401443 RGD:6483087 RGD:6483089 NCBI chr37:17,316,899...17,611,360
Ensembl chr37:17,466,678...17,607,803 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 treatment ISO associated with Subarachnoid Hemorrhage RGD PMID:26100626 PMID:27000704 PMID:33414375 RGD:155791672 RGD:155804286 RGD:155882440 NCBI chr12:49,669,849...49,740,039
Ensembl chr12:49,672,389...49,739,850 		JBrowse link
G MBL1 mannose binding lectin 1 disease_progression ISO RGD PMID:18183030 RGD:12910935 NCBI chr 4:29,419,886...29,424,377 JBrowse link
G MBP myelin basic protein ISO RGD PMID:18583256 RGD:7349333 NCBI chr 1:2,841,801...2,952,553
Ensembl chr 1:2,846,589...2,951,860 		JBrowse link
G MDM2 MDM2 proto-oncogene ISO protein:increased expression:brain cortex (rat) RGD PMID:15165363 RGD:2317397 NCBI chr10:10,936,288...10,963,118
Ensembl chr10:10,893,719...10,962,596 		JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:15922484 RGD:1641989
G MIR132 microRNA mir-132 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 9:46,153,531...46,153,590
Ensembl chr 9:46,153,511...46,153,611 		JBrowse link
G MIR144 microRNA mir-144 ISO RGD PMID:25089700 RGD:11576302 NCBI chr 9:43,031,035...43,031,094
Ensembl chr 9:43,031,035...43,031,094 		JBrowse link
G MIR153 microRNA mir-153 ISO RGD PMID:25089700 RGD:11576302 NCBI chr16:19,932,378...19,932,457
Ensembl chr16:19,932,378...19,932,457 		JBrowse link
G MIR183 microRNA mir-183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr14:7,068,542...7,068,603
Ensembl chr14:7,068,519...7,068,625 		JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:16671440 PMID:19631748 PMID:24661104 RGD:13207312 RGD:1582656 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293 		JBrowse link
G MPO myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 9:32,927,483...32,938,007
Ensembl chr 9:32,927,483...32,937,820 		JBrowse link
G MT-CO2 mitochondrially encoded cytochrome c oxidase II ISO mRNA, protein:increased expression:hippocampus RGD PMID:11686499 RGD:2302298 NCBI chr MT:7,034...7,717
Ensembl chr MT:7,034...7,717 		JBrowse link
G MT-III transcription initiation factor TFIID subunit 4 treatment ISO RGD PMID:10218634 PMID:10595827 PMID:16314047 RGD:6480628 RGD:9685803 RGD:9685805 NCBI chr 2:59,624,845...59,630,386 JBrowse link
G MT2A metallothionein 1H ISO mRNA:increased expression:dentate gyrus (rat)
mRNA:increased expression:liver (mouse)		 RGD PMID:15650329 PMID:22363575 RGD:6483812 RGD:6483847 NCBI chr 2:59,607,926...59,608,825
Ensembl chr 2:59,607,927...59,626,727 		JBrowse link
G MYOC myocilin ISO mRNA:increased expression:cerebral cortex (rat) RGD PMID:12799138 RGD:7401267 NCBI chr 7:27,335,314...27,346,821
Ensembl chr 7:27,335,314...27,346,820 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO protein:increased expression:lung: RGD PMID:18787991 PMID:25089700 RGD:11576302 RGD:5134971 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524 		JBrowse link
G NGB neuroglobin severity ISO RGD PMID:21915648 RGD:9743963 NCBI chr 8:50,081,960...50,086,071
Ensembl chr 8:50,081,960...50,085,435 		JBrowse link
G NGFR nerve growth factor receptor treatment ISO RGD PMID:23940017 RGD:10414074 NCBI chr 9:25,598,468...25,621,021
Ensembl chr 9:25,601,074...25,623,274 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO RGD PMID:11526986 RGD:10395358 NCBI chr 9:42,171,821...42,210,217
Ensembl chr 9:42,171,821...42,208,588 		JBrowse link
G NOX4 NADPH oxidase 4 ISO CTD Direct Evidence: therapeutic CTD PMID:36762617 NCBI chr21:10,615,153...10,782,927
Ensembl chr21:10,615,970...10,775,277 		JBrowse link
G NPPB natriuretic peptide B ISO associated with lung diseases;protein:increased expression:serum:
CTD Direct Evidence: therapeutic		 RGD
CTD		 PMID:19803787 PMID:23837838 RGD:7247620 NCBI chr 2:84,395,844...84,397,473 JBrowse link
G NPY neuropeptide Y ISO protein:increased expression:adrenal medulla RGD PMID:23570732 RGD:10448961 NCBI chr14:37,824,579...37,831,289
Ensembl chr14:37,823,861...37,831,443 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 treatment ISO mRNA:increased expression:lung
associated with Subarachnoid Hemorrhage		 RGD PMID:18787991 PMID:20864352 RGD:11035222 RGD:5134971 NCBI chr 5:79,979,593...79,990,875
Ensembl chr 5:79,978,865...79,989,860 		JBrowse link
G NT5E 5'-nucleotidase ecto ISO protein:altered expression:cerebral cortex (rat) RGD PMID:21337375 RGD:5134348 NCBI chr12:45,491,028...45,520,019
Ensembl chr12:45,491,733...45,518,405 		JBrowse link
G P2RY1 purinergic receptor P2Y1 ISO protein:increased expression:brain, astrocyte RGD PMID:19115395 RGD:2315811 NCBI chr23:47,249,496...47,253,203
Ensembl chr23:47,249,496...47,253,203 		JBrowse link
G PALLD palladin, cytoskeletal associated protein ISO protein:increased expression:brain, astrocyte RGD PMID:12932445 RGD:2325786 NCBI chr25:19,147,310...19,568,712
Ensembl chr25:19,146,898...19,553,679 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17640816 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127 		JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO mRNA,protein:increased expression:brain: RGD PMID:11421591 RGD:9835358 NCBI chr15:22,114,014...22,159,287 JBrowse link
G PDE4D phosphodiesterase 4D ISO mRNA, protein:alternative form, decreased phosphorylation:brain RGD PMID:23057870 RGD:7327147 NCBI chr 2:45,843,767...47,245,263
Ensembl chr 2:45,846,294...46,949,912 		JBrowse link
G PDGFA platelet derived growth factor subunit A ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr 6:16,271,082...16,293,246
Ensembl chr 6:16,270,104...16,292,396 		JBrowse link
G PDGFB platelet derived growth factor subunit B ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr13:46,729,722...46,775,828
Ensembl chr13:46,730,703...46,773,278 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO mRNA:increased expression:cerebral cortex, hippocampus RGD PMID:9645955 RGD:11084932 NCBI chr 4:58,925,922...58,963,639
Ensembl chr 4:58,926,351...58,962,283 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:22658532 RGD:6484732 NCBI chr 9:12,166,124...12,219,553
Ensembl chr 9:12,166,775...12,219,778 		JBrowse link
G PGLYRP1 peptidoglycan recognition protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 1:109,614,404...109,618,242
Ensembl chr 1:109,614,437...109,618,242 		JBrowse link
G PGR progesterone receptor ISO RGD PMID:23211561 RGD:7248711 NCBI chr21:447,197...552,511
Ensembl chr21:447,319...552,511 		JBrowse link
G PHB1 prohibitin 1 ISO protein:increased oxidation:cerebral cortex RGD PMID:17518533 RGD:2292409 NCBI chr 9:25,525,711...25,536,722
Ensembl chr 9:25,526,649...25,536,722 		JBrowse link
G PHB2 prohibitin 2 ISO RGD PMID:24566151 RGD:12903261 NCBI chr27:38,075,769...38,080,440
Ensembl chr27:38,075,652...38,080,109 		JBrowse link
G PIAS1 protein inhibitor of activated STAT 1 ISO protein:decreased expression:brain, nucleus RGD PMID:21545521 RGD:8693413 NCBI chr30:32,116,363...32,232,530
Ensembl chr30:32,119,311...32,228,945 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO agonist more effective in combination with simvastatin RGD PMID:18562561 RGD:5508455 NCBI chr10:19,934,020...20,006,096
Ensembl chr10:19,934,165...20,006,146 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha treatment ISO protein:decreased expression:frontal cortex (rat) RGD PMID:22642418 PMID:24345766 RGD:10059630 RGD:6484257 NCBI chr 3:85,645,942...86,284,570
Ensembl chr 3:86,016,140...86,281,269 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism
protein: :hippocampus 		CTD
RGD		 PMID:14499481 PMID:19751097 RGD:6483311 NCBI chr32:22,688,141...22,996,693
Ensembl chr32:22,688,143...22,996,688 		JBrowse link
G PRF1 perforin 1 ISO RGD PMID:20537642 RGD:6482807 NCBI chr 4:21,497,865...21,502,429
Ensembl chr 4:21,498,249...21,500,864 		JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO protein:increased expression:striatum, microglia (rat) RGD PMID:15234107 RGD:9850280 NCBI chr 6:74,932,789...74,986,573 JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO protein:increased expression:microglia, macrophage
protein:increased expression:microglial cells, macrophage, endothelial cell		 RGD PMID:11565600 PMID:12005397 PMID:19719848 RGD:5688162 RGD:5688239 RGD:5688242 NCBI chr 9:60,195,118...60,216,847
Ensembl chr 9:60,195,124...60,216,819 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12410334 PMID:19719848 PMID:20810888 PMID:21549006 PMID:21866634 RGD:5508191 RGD:5688162 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903 		JBrowse link
G PTPRZ1 protein tyrosine phosphatase receptor type Z1 ISO RGD PMID:12088737 RGD:727637 NCBI chr14:59,769,553...59,944,111
Ensembl chr14:59,827,650...59,943,315 		JBrowse link
G RCHY1 ring finger and CHY zinc finger domain containing 1 ISO protein:increased expression:cerebral cortex RGD PMID:21728064 RGD:10045359 NCBI chr32:67,136...94,053
Ensembl chr32:67,509...93,987 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO protein:increased expression:ileum RGD PMID:18288455 RGD:2298787 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875 		JBrowse link
G RET ret proto-oncogene ISO mRNA:increased expression:brain RGD PMID:18501516 RGD:2324932 NCBI chr28:3,946,132...3,995,505
Ensembl chr28:3,947,232...3,994,210 		JBrowse link
G RHOA ras homolog family member A ISO protein:increased expression:microglial cell, brain RGD PMID:17929039 RGD:2298888 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215 		JBrowse link
G ROBO1 roundabout guidance receptor 1 ISO mRNA:increased expression:brain
protein:increased expression:brain, immune cell		 RGD PMID:16262652 PMID:26550694 RGD:2316136 RGD:243048437 NCBI chr31:8,082,363...8,594,623
Ensembl chr31:7,626,126...8,593,728 		JBrowse link
G ROBO2 roundabout guidance receptor 2 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr31:9,415,390...11,047,710
Ensembl chr31:9,419,026...11,022,392 		JBrowse link
G ROBO3 roundabout guidance receptor 3 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr 5:9,563,353...9,579,111
Ensembl chr 5:9,563,345...9,579,289 		JBrowse link
G RPS27A ribosomal protein S27a ISO mRNA:decreased expression:cerebral cortex, hippocampus RGD PMID:17936732 RGD:11041870 NCBI chr10:56,132,924...56,135,327
Ensembl chr10:56,132,894...56,135,327 		JBrowse link
G S100B S100 calcium binding protein B severity ISO CTD Direct Evidence: marker/mechanism|therapeutic RGD
CTD		 PMID:11520488 PMID:21783483 PMID:21976236 RGD:5508761 NCBI chr31:39,783,990...39,788,289
Ensembl chr31:39,784,506...39,788,183 		JBrowse link
G SELE selectin E ISO protein:increased expression:brain RGD PMID:19107536 RGD:2313599 NCBI chr 7:28,888,503...28,898,787
Ensembl chr 7:28,888,197...28,898,786 		JBrowse link
G SERPINC1 serpin family C member 1 ISO CTD Direct Evidence: therapeutic CTD PMID:21534203 NCBI chr 7:25,322,668...25,333,022
Ensembl chr 7:25,316,129...25,332,987 		JBrowse link
G SERPINF1 serpin family F member 1 treatment ISO human gene in a rat model
protein:altered expression:cerebellum (rat)		 RGD PMID:17709187 PMID:20142768 RGD:8612994 RGD:8622925 NCBI chr 9:45,891,368...45,902,768
Ensembl chr 9:45,891,410...45,902,765 		JBrowse link
G SIRT1 sirtuin 1 treatment ISO RGD PMID:17970622 RGD:9497541 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279 		JBrowse link
G SKP2 S-phase kinase associated protein 2 ISO protein:increased expression:brain RGD PMID:19852587 RGD:2315049 NCBI chr 4:72,352,966...72,386,469
Ensembl chr 4:72,352,986...72,386,307 		JBrowse link
G SLC18A3 solute carrier family 18 member A3 ISO protein:decreased expression:brain RGD PMID:18848922 RGD:5686682 NCBI chr28:1,476,873...1,478,538
Ensembl chr28:1,476,774...1,478,505 		JBrowse link
G SLIT1 slit guidance ligand 1 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr28:10,351,758...10,519,322
Ensembl chr28:10,351,821...10,519,313 		JBrowse link
G SLIT2 slit guidance ligand 2 exacerbates ISO RGD PMID:26550694 RGD:243048437 NCBI chr 3:88,964,707...89,311,817
Ensembl chr 3:88,966,232...89,312,955 		JBrowse link
G SLIT3 slit guidance ligand 3 ISO mRNA:increased expression:brain RGD PMID:16262652 RGD:2316136 NCBI chr 4:42,506,680...43,099,053
Ensembl chr 4:42,508,426...43,094,714 		JBrowse link
G SNCA synuclein alpha ISO RGD PMID:14637093 PMID:25089700 RGD:11576302 RGD:6480195 NCBI chr32:12,915,871...13,079,338
Ensembl chr32:12,916,215...13,060,383 		JBrowse link
G SNCB synuclein beta ISO RGD PMID:14637093 RGD:6480195 NCBI chr 4:36,710,236...36,719,455
Ensembl chr 4:36,616,039...36,764,501 		JBrowse link
G SNCG synuclein gamma ISO RGD PMID:14637093 RGD:6480195 NCBI chr 4:34,604,867...34,608,851
Ensembl chr 4:34,605,091...34,608,842 		JBrowse link
G SNW1 SNW domain containing 1 ISO mRNA, protein:increased expression:cerebral cortex (rat) RGD PMID:22965216 RGD:11035237 NCBI chr 8:50,478,924...50,512,360
Ensembl chr 8:50,479,338...50,512,243 		JBrowse link
G SOD1 superoxide dismutase 1 ISO RGD PMID:16248885 RGD:1581214 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815 		JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:16248885 PMID:24462953 RGD:1581214 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO mRNA:increased expression:brain, blood vessel RGD PMID:9704602 RGD:2300066 NCBI chr 4:57,659,541...57,682,147
Ensembl chr 4:57,659,650...57,681,711 		JBrowse link
G SSTR2 somatostatin receptor 2 ISO RGD PMID:11879809 RGD:2325002 NCBI chr 9:6,989,488...7,004,851
Ensembl chr 9:6,996,874...7,000,778 		JBrowse link
G SSTR3 somatostatin receptor 3 ISO RGD PMID:11879809 RGD:2325002 NCBI chr10:27,324,067...27,332,570
Ensembl chr10:27,329,174...27,330,451 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO RGD PMID:21596098 RGD:6483023 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO protein:increased phosphorylation:brain RGD PMID:21596098 PMID:22145815 PMID:22827467 RGD:6483023 RGD:6892706 RGD:8694312 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G STRN striatin ISO RGD PMID:16351572 RGD:2311293 NCBI chr17:29,264,693...29,364,273
Ensembl chr17:29,272,833...29,332,869 		JBrowse link
G TARDBP TAR DNA binding protein ISO RGD PMID:22101322 RGD:5687195 NCBI chr 2:84,987,752...84,998,136
Ensembl chr 2:84,989,952...84,998,593 		JBrowse link
G TH tyrosine hydroxylase ISO protein:decreased activity:striatum (rat) RGD PMID:21047500 RGD:5128822 NCBI chr18:46,327,136...46,334,973
Ensembl chr18:46,327,137...46,335,602 		JBrowse link
G THBD thrombomodulin onset ISO RGD PMID:17895610 RGD:5685007 NCBI chr24:599,773...601,649
Ensembl chr24:599,773...601,649 		JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr11:5,312,383...5,313,099
Ensembl chr11:5,312,383...5,313,099 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 ISO mRNA:increased expression:brain, astrocytes RGD PMID:10719361 RGD:2290468 NCBI chr  X:41,201,623...41,205,314
Ensembl chr  X:41,201,638...41,205,310 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO mRNA:increased expression:brain, neuron, microglial cell RGD PMID:10719361 RGD:2290468 NCBI chr 9:2,521,882...2,533,883
Ensembl chr 9:2,521,882...2,533,989 		JBrowse link
G TJP1 tight junction protein 1 ISO RGD PMID:19889224 RGD:2325128 NCBI chr 3:38,997,122...39,076,617
Ensembl chr 3:38,997,076...39,241,574 		JBrowse link
G TLR1 toll like receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr 3:73,504,359...73,544,822
Ensembl chr 3:73,539,715...73,544,624 		JBrowse link
G TLR2 toll like receptor 2 ISO mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:18316784 PMID:21549006 RGD:2312713 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241 		JBrowse link
G TLR4 toll like receptor 4 ISO mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:18316784 PMID:21549006 RGD:2312713 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G TLR9 toll like receptor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21549006 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114 		JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:10674461 PMID:19800810 PMID:21549006 RGD:13825262 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425 		JBrowse link
G TNFRSF13B TNF receptor superfamily member 13B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 5:42,448,976...42,483,792
Ensembl chr 5:42,449,053...42,482,740 		JBrowse link
G TNFRSF13C TNF receptor superfamily member 13C ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr10:23,430,960...23,434,972
Ensembl chr10:23,433,052...23,438,946 		JBrowse link
G TNFRSF14 TNF receptor superfamily member 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 5:57,386,190...57,416,864
Ensembl chr 5:57,411,529...57,416,512 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO protein:increased expression:brain
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:17074049 PMID:21549006 RGD:1624183 NCBI chr27:38,641,837...38,654,693
Ensembl chr27:38,638,753...38,700,282 		JBrowse link
G TNFSF10 TNF superfamily member 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr34:36,719,249...36,734,989
Ensembl chr34:36,670,849...36,735,060 		JBrowse link
G TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 5:32,473,543...32,481,596
Ensembl chr 5:32,473,083...32,481,121 		JBrowse link
G TRAF4 TNF receptor associated factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23159883 NCBI chr 9:42,933,638...42,940,033
Ensembl chr 9:42,933,750...42,939,520 		JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 ISO mRNA, protein:increased expression:cerebral cortex, hippocampus RGD PMID:20309649 RGD:9999437 NCBI chr31:38,201,075...38,224,076 JBrowse link
G UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 ISO mRNA:decreased expression:cerebral cortex, hippocampus (rat) RGD PMID:17936732 RGD:11041870 NCBI chr20:44,477,128...44,480,023
Ensembl chr20:44,477,130...44,479,948 		JBrowse link
G UCP2 uncoupling protein 2 ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:12858170 RGD:7204436 NCBI chr21:24,304,410...24,311,392
Ensembl chr21:24,304,457...24,311,128 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:12230324 PMID:18065154 RGD:1580574 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965 		JBrowse link
G VEGFB vascular endothelial growth factor B ISO mRNA, protein:increased expression:brain RGD PMID:12230324 RGD:1580574 NCBI chr18:52,821,348...52,824,649
Ensembl chr18:52,821,365...52,824,655 		JBrowse link
G VIM vimentin ISO protein:increased expression:brain RGD PMID:15527750 PMID:19728994 RGD:6480519 RGD:6480527 NCBI chr 2:19,671,316...19,679,367
Ensembl chr 2:19,671,316...19,679,466 		JBrowse link
G XDH xanthine dehydrogenase treatment ISO RGD PMID:26528358 RGD:13208950 NCBI chr17:24,900,708...24,960,748
Ensembl chr17:24,901,447...24,971,935 		JBrowse link
Chronic Brain Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E susceptibility ISO DNA:polymorphism:exon: RGD PMID:9214529 RGD:7495763 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440 		JBrowse link
G TARDBP TAR DNA binding protein ISO protein:increased expression:brain RGD PMID:20720505 RGD:5687179 NCBI chr 2:84,987,752...84,998,136
Ensembl chr 2:84,989,952...84,998,593 		JBrowse link
Closed Head Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 ISO protein:increased expression:neuron RGD PMID:16004578 RGD:6483315 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236 		JBrowse link
G GFAP glial fibrillary acidic protein ISO RGD PMID:8833197 RGD:6480531 NCBI chr 9:18,569,868...18,579,463
Ensembl chr 9:18,569,892...18,579,461 		JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 ISO human protein in a rat model RGD PMID:17014847 RGD:13504858 NCBI chr28:12,352,658...12,377,960
Ensembl chr28:12,352,659...12,414,579 		JBrowse link
G IGF1 insulin like growth factor 1 ISO protein:decreased expression:serum: RGD PMID:12002507 RGD:8548865 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO protein:decreased expression:serum: RGD PMID:12002507 RGD:8548865 NCBI chr16:1,021,855...1,027,604
Ensembl chr16:1,021,972...1,026,392 		JBrowse link
G VIM vimentin ISO RGD PMID:8833197 RGD:6480531 NCBI chr 2:19,671,316...19,679,367
Ensembl chr 2:19,671,316...19,679,466 		JBrowse link
Corneal Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28038895 NCBI chr 5:40,466,237...40,474,272
Ensembl chr 5:40,466,237...40,474,457 		JBrowse link
G TP63 tumor protein p63 ISO RGD PMID:12167247 RGD:11568649 NCBI chr34:21,766,861...21,985,095
Ensembl chr34:21,766,496...21,983,046 		JBrowse link
Corneal Perforation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma ISO mRNA,protein:increased expression:corneal RGD PMID:15832292 RGD:8157597 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
Cranial Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 ISO mRNA:increased expression:superior cervical ganglion RGD PMID:16420416 RGD:2289006 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:15153618 RGD:4891994 NCBI chr 2:59,022,794...59,032,095
Ensembl chr 2:59,022,794...59,032,095 		JBrowse link
Diffuse Brain Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G S100B S100 calcium binding protein B ISO CTD Direct Evidence: marker/mechanism CTD PMID:30076900 NCBI chr31:39,783,990...39,788,289
Ensembl chr31:39,784,506...39,788,183 		JBrowse link
Eye Burns term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 treatment ISO RGD PMID:22553604 RGD:7364851 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057 		JBrowse link
G IL1B interleukin 1 beta ISO protein:increased expression:retina RGD PMID:9618720 RGD:7794723 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO protein:increased expression:cornea, neutrophil, macrophage (rat) RGD PMID:24194635 RGD:8552904 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
Eye Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF2 fibroblast growth factor 2 ISO protein:increased expression:lens RGD PMID:15273655 RGD:8655664 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151 		JBrowse link
G MIR183 microRNA mir-183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27208084 NCBI chr14:7,068,542...7,068,603
Ensembl chr14:7,068,519...7,068,625 		JBrowse link
G MIR96 microRNA mir-96 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27208084 NCBI chr14:7,068,754...7,068,842
Ensembl chr14:7,068,754...7,068,842 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma treatment ISO RGD PMID:18658087 RGD:8552893 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
Facial Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1 adenylate cyclase activating polypeptide 1 ISO mRNA:increased expression:facial VII nucleus RGD PMID:19427307 RGD:2325258 NCBI chr 7:67,682,421...67,691,035 JBrowse link
G ATF2 activating transcription factor 2 ISO RGD PMID:9813301 RGD:10047413 NCBI chr36:19,032,376...19,103,382
Ensembl chr36:19,010,717...19,103,292 		JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO RGD PMID:19922414 RGD:6892922 NCBI chr20:42,382,380...42,398,449
Ensembl chr20:42,383,135...42,384,217 		JBrowse link
G CD59 CD59 molecule ISO mRNA, protein:increased expression:facial VII nucleus RGD PMID:9846834 RGD:1600495 NCBI chr18:33,977,433...33,999,145
Ensembl chr18:33,977,480...33,998,329 		JBrowse link
G CLU clusterin ISO protein:increased expression:neuron,astrocyte RGD PMID:10800205 RGD:408418725 NCBI chr25:29,982,811...29,999,565
Ensembl chr25:29,982,811...29,999,563 		JBrowse link
G CSF1 colony stimulating factor 1 ISO protein:increased expression:facial VII nerve, microglial cell RGD PMID:20831658 RGD:5131509 NCBI chr 6:42,028,454...42,047,028
Ensembl chr 6:42,034,149...42,049,371 		JBrowse link
G CTSS cathepsin S ISO RGD PMID:17539023 RGD:5686912 NCBI chr17:59,893,840...59,910,878
Ensembl chr17:59,893,840...59,910,849 		JBrowse link
G GFRA1 GDNF family receptor alpha 1 ISO mRNA:increased expression:facial VII nucleus RGD PMID:9582449 RGD:6218984 NCBI chr28:26,707,592...26,910,029
Ensembl chr28:26,709,645...26,909,992 		JBrowse link
G HGF hepatocyte growth factor treatment ISO RGD PMID:21562589 RGD:8548634 NCBI chr18:21,329,688...21,410,257
Ensembl chr18:21,332,817...21,410,263 		JBrowse link
G MT-III transcription initiation factor TFIID subunit 4 treatment ISO RGD PMID:14625437 RGD:9685806 NCBI chr 2:59,624,845...59,630,386 JBrowse link
G NDUFA5 NADH:ubiquinone oxidoreductase subunit A5 ISO mRNA:increased expression:skeletal muscle RGD PMID:8875451 RGD:2302319 NCBI chr14:11,995,862...12,008,257 JBrowse link
G RET ret proto-oncogene ISO mRNA:increased expression:facial VII nucleus RGD PMID:9582449 RGD:6218984 NCBI chr28:3,946,132...3,995,505
Ensembl chr28:3,947,232...3,994,210 		JBrowse link
Hypoglossal Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1B activin A receptor type 1B ISO RGD PMID:9013782 RGD:151665480 NCBI chr27:3,009,710...3,029,726
Ensembl chr27:2,994,857...3,042,396 		JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 ISO mRNA:increased expression:hypoglossal nerve RGD PMID:11311987 RGD:5037239 NCBI chr31:22,169,821...22,178,879
Ensembl chr31:22,170,381...22,178,945 		JBrowse link
G AIF1 allograft inflammatory factor 1 ISO RGD PMID:9698327 RGD:704401 NCBI chr12:1,104,350...1,106,179
Ensembl chr12:1,104,394...1,106,177 		JBrowse link
G CSNK2B casein kinase 2 beta ISO RGD PMID:11068334 RGD:11565824 NCBI chr12:1,149,467...1,154,417
Ensembl chr12:1,149,548...1,154,418 		JBrowse link
G FGF2 fibroblast growth factor 2 ISO RGD PMID:9183688 RGD:8655640 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO RGD PMID:9183688 RGD:8655640 NCBI chr16:27,029,902...27,080,514
Ensembl chr16:27,031,588...27,078,261 		JBrowse link
G GFRA1 GDNF family receptor alpha 1 ISO mRNA:increased expression:hypoglossal XII nerve RGD PMID:10407179 RGD:6218979 NCBI chr28:26,707,592...26,910,029
Ensembl chr28:26,709,645...26,909,992 		JBrowse link
G IL1R1 interleukin 1 receptor type 1 ISO mRNA:increased expression:hypoglossal nerve RGD PMID:11311987 RGD:5037239 NCBI chr10:40,825,986...40,897,898
Ensembl chr10:40,827,377...40,897,596 		JBrowse link
G MCAM melanoma cell adhesion molecule ISO RGD PMID:10076889 RGD:7364787 NCBI chr 5:14,590,252...14,598,901
Ensembl chr 5:14,567,238...14,598,149 		JBrowse link
G MME membrane metalloendopeptidase ISO RGD PMID:8201016 RGD:13801045 NCBI chr23:48,966,222...49,059,919
Ensembl chr23:48,971,066...49,059,919 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO RGD PMID:7769990 RGD:7327191 NCBI chr20:48,416,730...48,425,237
Ensembl chr20:48,409,045...48,426,669 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta ISO RGD PMID:7769990 RGD:7327191 NCBI chr 6:63,615,445...63,729,386
Ensembl chr 6:63,618,323...63,730,146 		JBrowse link
G RET ret proto-oncogene ISO mRNA:increased expression:hypoglossal XII nerve RGD PMID:10407179 RGD:6218979 NCBI chr28:3,946,132...3,995,505
Ensembl chr28:3,947,232...3,994,210 		JBrowse link
G SMAD1 SMAD family member 1 ISO mRNA:increased expression:hypoglossal nucleus RGD PMID:17166487 RGD:1643227 NCBI chr15:44,093,491...44,171,177
Ensembl chr15:44,095,497...44,170,098 		JBrowse link
G SMAD2 SMAD family member 2 ISO mRNA:increased expression:hypoglossal nucleus RGD PMID:17166487 RGD:1643227 NCBI chr 7:43,696,883...43,778,063
Ensembl chr 7:43,700,445...43,769,983 		JBrowse link
G SMAD3 SMAD family member 3 ISO mRNA:increased expression:hypoglossal nucleus RGD PMID:17166487 RGD:1643227 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337 		JBrowse link
G SMAD4 SMAD family member 4 ISO mRNA:increased expression:hypoglossal nucleus RGD PMID:17166487 RGD:1643227 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
G SMAD7 SMAD family member 7 ISO mRNA:increased expression:hypoglossal nucleus RGD PMID:17166487 RGD:1643227 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749 		JBrowse link
G SMAD9 SMAD family member 9 ISO mRNA:decreased expression:hypoglossal nucleus RGD PMID:17166487 RGD:1643227 NCBI chr25:3,768,851...3,844,645
Ensembl chr25:3,779,197...3,841,321 		JBrowse link
G TXNRD1 thioredoxin reductase 1 ISO mRNA, protein:increased expression:neuron RGD PMID:19833109 RGD:5133729 NCBI chr10:33,904,065...34,021,549
Ensembl chr10:33,886,343...34,021,696 		JBrowse link
Intracranial Subdural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GP6 glycoprotein VI platelet exacerbates ISO RGD PMID:21258336 RGD:401824683 NCBI chr 1:102,586,229...102,612,067
Ensembl chr 1:102,585,544...102,613,905 		JBrowse link
G MDM2 MDM2 proto-oncogene treatment ISO RGD PMID:34334113 RGD:155882538 NCBI chr10:10,936,288...10,963,118
Ensembl chr10:10,893,719...10,962,596 		JBrowse link
G ZEB2 zinc finger E-box binding homeobox 2 treatment ISO protein:increased expression:brain (rat) RGD PMID:34334113 RGD:155882538 NCBI chr19:46,419,812...46,541,888
Ensembl chr19:46,423,998...46,542,122 		JBrowse link
Mandibular Fractures term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 ISO mRNA:decreased expression:bone RGD PMID:19607804 RGD:5147852 NCBI chr 1:31,522,911...31,525,342
Ensembl chr 1:31,523,799...31,524,995 		JBrowse link
G IHH Indian hedgehog signaling molecule ISO RGD PMID:23992905 RGD:12911207 NCBI chr37:25,616,942...25,622,989 JBrowse link
Oculomotor Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO mRNA:increased expression:motor neuron RGD PMID:21456016 RGD:5684341 NCBI chr 1:74,447,927...74,777,910
Ensembl chr 1:74,449,060...74,777,032 		JBrowse link
Optic Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO protein:decreased expression:retina RGD PMID:22649251 RGD:329347828 NCBI chr 7:30,576,445...30,660,926
Ensembl chr 7:30,577,591...30,660,926 		JBrowse link
G ADNP activity dependent neuroprotector homeobox ISO RGD PMID:18414890 RGD:2312783 NCBI chr24:37,211,776...37,245,938
Ensembl chr24:37,213,942...37,243,702 		JBrowse link
G AMIGO3 adhesion molecule with Ig like domain 3 treatment ISO RGD PMID:23613963 RGD:14390159 NCBI chr20:39,554,028...39,557,129
Ensembl chr20:39,554,629...39,556,155 		JBrowse link
G AQP4 aquaporin 4 ISO RGD PMID:20216911 RGD:2326035 NCBI chr 7:61,855,617...61,868,953
Ensembl chr 7:61,855,744...61,865,089 		JBrowse link
G AQP9 aquaporin 9 ISO RGD PMID:20216911 RGD:2326035 NCBI chr30:23,223,413...23,271,893
Ensembl chr30:23,225,331...23,269,076 		JBrowse link
G ARG2 arginase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30618589 NCBI chr 8:41,588,051...41,619,406
Ensembl chr 8:41,588,150...41,619,402 		JBrowse link
G ATF2 activating transcription factor 2 ISO RGD PMID:10366744 RGD:10047417 NCBI chr36:19,032,376...19,103,382
Ensembl chr36:19,010,717...19,103,292 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO mRNA:increased expression:optic nerve, retina RGD PMID:24357921 RGD:10054098 NCBI chr 1:107,423,388...107,426,464
Ensembl chr 1:107,422,424...107,426,464 		JBrowse link
G BCL2 BCL2 apoptosis regulator ISO mRNA:decreased expression:optic nerve, retina RGD PMID:24357921 RGD:10054098 NCBI chr 1:13,733,849...13,900,653
Ensembl chr 1:13,731,406...13,900,658 		JBrowse link
G BDNF brain derived neurotrophic factor treatment ISO RGD PMID:9520478 PMID:11050383 PMID:15140649 RGD:8655584 RGD:8655586 RGD:8655637 NCBI chr21:48,191,580...48,243,699
Ensembl chr21:48,192,670...48,204,480 		JBrowse link
G C3 complement C3 ISO mRNA:increased expression:optic nerve RGD PMID:14577867 RGD:5129542 NCBI chr20:53,566,226...53,598,365
Ensembl chr20:53,566,261...53,598,761 		JBrowse link
G CDK2 cyclin dependent kinase 2 ISO mRNA:increased expression:retina RGD PMID:16723461 RGD:2293567 NCBI chr10:300,863...306,546
Ensembl chr10:300,903...305,438 		JBrowse link
G CFL1 cofilin 1 treatment ISO RGD PMID:27443501 RGD:11568693 NCBI chr18:51,404,649...51,408,240
Ensembl chr18:51,401,659...51,408,212 		JBrowse link
G CLU clusterin ISO RGD PMID:14577867 RGD:5129542 NCBI chr25:29,982,811...29,999,565
Ensembl chr25:29,982,811...29,999,563 		JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO mRNA:increased expression:retina (rat) RGD PMID:20187850 RGD:151665810 NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510 		JBrowse link
G CSF3 colony stimulating factor 3 treatment ISO RGD PMID:20144610 RGD:11039471 NCBI chr 9:22,529,643...22,532,326
Ensembl chr 9:22,530,698...22,533,108 		JBrowse link
G CTSB cathepsin B ISO protein:increased expression:retina (rat) RGD PMID:18775855 RGD:2315508 NCBI chr25:26,048,237...26,056,570
Ensembl chr25:26,048,253...26,055,801 		JBrowse link
G EDN1 endothelin 1 ISO protein:increased expression:retina RGD PMID:18600494 RGD:4892579 NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383 		JBrowse link
G EDNRA endothelin receptor type A ISO mRNA:increased expression:retina RGD PMID:18600494 RGD:4892579 NCBI chr15:45,823,472...45,878,527
Ensembl chr15:45,823,560...45,876,463 		JBrowse link
G EDNRB endothelin receptor type B ISO mRNA:increased expression:retina RGD PMID:18600494 RGD:4892579 NCBI chr22:31,415,324...31,438,772
Ensembl chr22:31,417,308...31,437,587 		JBrowse link
G EP300 E1A binding protein p300 ISO human gene in rat model RGD PMID:21705428 RGD:7349392 NCBI chr10:24,076,538...24,156,708
Ensembl chr10:24,077,971...24,156,396 		JBrowse link
G FGF2 fibroblast growth factor 2 treatment ISO RGD PMID:14664816 RGD:8554854 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase ISO mRNA:increased expression:retina RGD PMID:33664770 RGD:329951020 NCBI chr 2:61,699,864...62,080,199
Ensembl chr 2:61,652,236...62,080,059 		JBrowse link
G GDNF glial cell derived neurotrophic factor ISO RGD PMID:15144875 RGD:6218970 NCBI chr 4:70,966,694...70,991,860
Ensembl chr 4:70,971,432...70,989,714 		JBrowse link
G GFRA1 GDNF family receptor alpha 1 ISO RGD PMID:15144875 RGD:6218970 NCBI chr28:26,707,592...26,910,029
Ensembl chr28:26,709,645...26,909,992 		JBrowse link
G GFRA2 GDNF family receptor alpha 2 ISO RGD PMID:15144875 RGD:6218970 NCBI chr25:35,436,790...35,521,661
Ensembl chr25:35,436,317...35,520,365 		JBrowse link
G HGF hepatocyte growth factor treatment ISO RGD PMID:21443522 RGD:8548549 NCBI chr18:21,329,688...21,410,257
Ensembl chr18:21,332,817...21,410,263 		JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO protein:increased expression:retina:
protein: altered activity: eye		 RGD PMID:19484445 PMID:23648097 RGD:10046025 RGD:5686431 NCBI chr 3:41,795,337...42,096,255
Ensembl chr 3:41,794,623...42,090,387 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:10366744 RGD:10047417 NCBI chr 5:50,966,698...50,968,939 JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 ISO RGD PMID:20216911 RGD:2326035 NCBI chr38:22,114,718...22,143,625
Ensembl chr38:22,130,508...22,140,813 		JBrowse link
G MT-CO1 mitochondrially encoded cytochrome c oxidase I ISO mRNA:increased expression:retina RGD PMID:12076086 RGD:8662362 NCBI chr MT:5,349...6,893
Ensembl chr MT:5,349...6,893 		JBrowse link
G MYRF myelin regulatory factor ISO mRNA:decreased expression: oligodendrocyte RGD PMID:29915135 RGD:213230153 NCBI chr18:54,690,073...54,723,046
Ensembl chr18:54,692,453...54,723,085 		JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase treatment ISO RGD PMID:28032230 RGD:13781885 NCBI chr18:14,110,045...14,211,268
Ensembl chr18:13,993,022...14,208,657 		JBrowse link
G NCAM1 neural cell adhesion molecule 1 ISO RGD PMID:18757519 RGD:2326023 NCBI chr 5:19,895,587...20,192,334
Ensembl chr 5:19,895,613...20,191,995 		JBrowse link
G NEFM neurofilament medium chain ISO RGD PMID:8501527 RGD:9743936 NCBI chr25:32,493,517...32,498,615
Ensembl chr25:32,493,675...32,498,570 		JBrowse link
G NEO1 neogenin 1 ISO protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chr30:36,387,425...36,622,491
Ensembl chr30:36,387,259...36,622,154 		JBrowse link
G NGF nerve growth factor ISO protein:increased expression:retina RGD PMID:28067793 RGD:402463954 NCBI chr17:52,900,647...52,901,607
Ensembl chr17:52,900,647...52,901,607 		JBrowse link
G NGFR nerve growth factor receptor ISO RGD PMID:20943663 RGD:5508695 NCBI chr 9:25,598,468...25,621,021
Ensembl chr 9:25,601,074...25,623,274 		JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 ISO RGD PMID:20943663 RGD:5508695 NCBI chr 7:41,140,931...41,159,326
Ensembl chr 7:41,140,879...41,159,288 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 treatment ISO RGD PMID:20357199 PMID:34245756 RGD:5684908 RGD:597015764 NCBI chr 1:74,447,927...74,777,910
Ensembl chr 1:74,449,060...74,777,032 		JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO mRNA:increased expression:retina: RGD PMID:12836167 RGD:1299297 NCBI chr15:22,114,014...22,159,287 JBrowse link
G PAX6 paired box 6 ISO protein:increased expression:retina (rat) RGD PMID:23297010 RGD:8552379
G PDGFB platelet derived growth factor subunit B ISO protein:decreased expression:nerve fiber: RGD PMID:9893812 RGD:10449496 NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO protein:increased expression:optic nerve (rat) RGD PMID:22336118 RGD:6767293 NCBI chr 9:12,166,124...12,219,553
Ensembl chr 9:12,166,775...12,219,778 		JBrowse link
G PLAU plasminogen activator, urokinase ISO mRNA:increased expression:optic nerve (rat) RGD PMID:20798533 RGD:6483802 NCBI chr 4:24,329,139...24,333,893
Ensembl chr 4:24,328,925...24,334,851 		JBrowse link
G PTPN5 protein tyrosine phosphatase non-receptor type 5 ISO protein:increased expression:retina (rat) RGD PMID:15555919 RGD:9835027 NCBI chr21:41,097,563...41,154,247
Ensembl chr21:41,097,569...41,136,706 		JBrowse link
G RHOA ras homolog family member A ISO protein:increased expression, altered localization:retina RGD PMID:17534117 RGD:1642826 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215 		JBrowse link
G SNW1 SNW domain containing 1 ISO protein:increased expression:retina (rat) RGD PMID:25074585 RGD:11035254 NCBI chr 8:50,478,924...50,512,360
Ensembl chr 8:50,479,338...50,512,243 		JBrowse link
G TLR2 toll like receptor 2 treatment ISO RGD PMID:19661221 RGD:597538516 NCBI chr15:51,454,557...51,465,429
Ensembl chr15:51,454,695...51,465,241 		JBrowse link
G TLR4 toll like receptor 4 ISO protein:increased expression:optic nerve RGD PMID:23103505 RGD:7794777 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A ISO RGD PMID:14697498 PMID:18552980 RGD:7794683 RGD:8661743 NCBI chr27:38,641,837...38,654,693
Ensembl chr27:38,638,753...38,700,282 		JBrowse link
G TRADD TNFRSF1A associated via death domain ISO protein:increased expression: retina RGD PMID:18552980 RGD:7794683 NCBI chr 5:82,200,430...82,211,430
Ensembl chr 5:82,206,111...82,210,963 		JBrowse link
G YBX3 Y-box binding protein 3 ISO mRNA:increased expression:retinal ganglion cell RGD PMID:11750989 RGD:2311250 NCBI chr27:35,043,756...35,066,230
Ensembl chr27:35,043,699...35,066,227 		JBrowse link
G ZC3H7B zinc finger CCCH-type containing 7B ISO protein:decreased expression:retinal ganglion cell layer (rat) RGD PMID:21705428 RGD:7349392 NCBI chr10:23,882,379...23,944,850
Ensembl chr10:23,884,981...23,920,131 		JBrowse link
Penetrating Eye Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF2 fibroblast growth factor 2 ISO mRNA:increased expression:retina RGD PMID:9268592 RGD:8655567 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151 		JBrowse link
G NEO1 neogenin 1 ISO protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chr30:36,387,425...36,622,491
Ensembl chr30:36,387,259...36,622,154 		JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a ISO protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chr 3:47,044,342...47,089,923
Ensembl chr 3:47,061,910...47,089,294 		JBrowse link
Penetrating Head Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO protein:increased expression,increased activity:cerebral cortex: RGD PMID:16672190 RGD:9685448 NCBI chr28:9,181,851...9,311,835
Ensembl chr28:9,211,050...9,323,939 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO mRNA,protein:increased expression:astrocyte,macrophage,neutrophil: RGD PMID:11168551 RGD:10402049 NCBI chr16:27,029,902...27,080,514
Ensembl chr16:27,031,588...27,078,261 		JBrowse link
G GFAP glial fibrillary acidic protein ISO RGD PMID:10225952 RGD:6480471 NCBI chr 9:18,569,868...18,579,463
Ensembl chr 9:18,569,892...18,579,461 		JBrowse link
G PDGFB platelet derived growth factor subunit B ISO protein:increased expression:neuron: RGD PMID:7526956 RGD:10449485 NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746 		JBrowse link
G VIM vimentin ISO RGD PMID:10225952 RGD:6480471 NCBI chr 2:19,671,316...19,679,367
Ensembl chr 2:19,671,316...19,679,466 		JBrowse link
Post-Head Injury Coma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRH thyrotropin releasing hormone ISO CTD Direct Evidence: therapeutic CTD PMID:8690305 NCBI chr20:5,219,495...5,222,914
Ensembl chr20:5,219,594...5,222,866 		JBrowse link
Skull Fractures term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 treatment ISO RGD PMID:16332232 RGD:8699514 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557 		JBrowse link
G IGF1 insulin like growth factor 1 ISO protein:decreased expression:serum: RGD PMID:12002507 RGD:8548865 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794 		JBrowse link
Subdural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLAT plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:1899364 NCBI chr16:23,469,590...23,496,013 JBrowse link
traumatic brain injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM10 ADAM metallopeptidase domain 10 ISO RGD PMID:22489706 RGD:13703033 NCBI chr30:23,605,724...23,732,038
Ensembl chr30:23,606,517...23,731,823 		JBrowse link
G AHR aryl hydrocarbon receptor ISO protein:increased expression:T cell, neuron, brain cortex, hippocampus RGD PMID:27506546 RGD:405878081 NCBI chr14:31,743,704...31,793,484
Ensembl chr14:31,686,170...31,791,444 		JBrowse link
G APP amyloid beta precursor protein treatment ISO RGD PMID:29320530 RGD:13782048 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337 		JBrowse link
G B9D2 B9 domain containing 2 treatment ISO RGD PMID:28433746 RGD:14995478 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO RGD PMID:24582457 RGD:13782254 NCBI chr18:52,781,335...52,791,789
Ensembl chr18:52,781,921...52,791,405 		JBrowse link
G BDNF brain derived neurotrophic factor ISO mRNA:increased expression:CA3 field of hippocampus, dentate gyrus RGD PMID:10925157 RGD:596936229 NCBI chr21:48,191,580...48,243,699
Ensembl chr21:48,192,670...48,204,480 		JBrowse link
G BID BH3 interacting domain death agonist disease_progression
severity		 ISO RGD PMID:12172380 PMID:15307896 RGD:5509821 RGD:632018 NCBI chr27:45,344,304...45,355,735
Ensembl chr27:45,337,145...45,384,059 		JBrowse link
G CAPN1 calpain 1 severity ISO protein:increased expression:cytosol, plasma membrane RGD PMID:9469158 PMID:15307896 RGD:13792664 RGD:5509821 NCBI chr18:51,983,266...52,010,831
Ensembl chr18:51,983,824...52,010,757 		JBrowse link
G CAPN2 calpain 2 severity ISO RGD PMID:9469158 PMID:15307896 RGD:13792664 RGD:5509821 NCBI chr 7:40,333,379...40,367,158
Ensembl chr 7:40,334,012...40,377,037 		JBrowse link
G CASP3 caspase 3 severity ISO protein:increased expression:cerebral cortex RGD PMID:15307896 PMID:27614125 RGD:329961568 RGD:5509821 NCBI chr16:45,920,074...45,940,507
Ensembl chr16:45,920,071...45,940,505 		JBrowse link
G CASP8 caspase 8 severity
disease_progression		 ISO RGD PMID:12172380 PMID:15307896 RGD:5509821 RGD:632018 NCBI chr37:10,362,071...10,402,108
Ensembl chr37:10,391,048...10,401,822 		JBrowse link
G CASP9 caspase 9 disease_progression
severity		 ISO RGD PMID:12172380 PMID:15307896 RGD:5509821 RGD:632018 NCBI chr 2:82,033,759...82,076,710
Ensembl chr 2:82,031,563...82,090,484 		JBrowse link
G CCNG1 cyclin G1 treatment ISO RGD PMID:18612315 PMID:24398934 RGD:151356934 RGD:151356935 NCBI chr 4:47,800,697...47,808,259
Ensembl chr 4:47,801,575...47,808,211 		JBrowse link
G CD163 CD163 molecule ISO protein:increased expression:brain, macrophage (rat) RGD PMID:22583855 RGD:127285798 NCBI chr27:37,669,757...37,700,746
Ensembl chr27:37,669,827...37,753,106 		JBrowse link
G CD8A CD8 subunit alpha ISO mRNA:increased expression:brain (mouse) RGD PMID:31383034 RGD:124715446 NCBI chr17:38,396,022...38,400,508
Ensembl chr17:38,369,414...38,400,508 		JBrowse link
G CIT citron rho-interacting serine/threonine kinase ISO mRNA:decreased expression:cerebral cortex��(rat) RGD PMID:12503083 RGD:2317873 NCBI chr26:15,721,500...15,885,133
Ensembl chr26:15,723,690...15,884,343 		JBrowse link
G CTNNB1 catenin beta 1 treatment ISO RGD PMID:26296359 RGD:597538582 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 treatment ISO RGD PMID:26435412 RGD:27095897 NCBI chr32:598,406...599,925
Ensembl chr32:597,987...599,979 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 ISO protein:increased expression:cerebral cortex RGD PMID:27614125 RGD:329961568 NCBI chr28:2,895,916...2,903,543 JBrowse link
G CYP2D15 cytochrome P450 family 2 subfamily D member 15 treatment ISO RGD PMID:26068867 RGD:401901590 NCBI chr10:23,255,259...23,259,380
Ensembl chr10:23,255,249...23,259,298 		JBrowse link
G DRD1 dopamine receptor D1 treatment ISO RGD PMID:24047867 RGD:13506948 NCBI chr 4:37,550,454...37,554,641
Ensembl chr 4:37,549,708...37,553,287 		JBrowse link
G DRD2 dopamine receptor D2 treatment ISO RGD PMID:24047867 RGD:13506948 NCBI chr 5:19,732,842...19,795,241
Ensembl chr 5:19,732,836...19,795,241 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase ISO mRNA:decreased expression:cerebral cortex RGD PMID:31992337 RGD:329901857 NCBI chr 2:61,699,864...62,080,199
Ensembl chr 2:61,652,236...62,080,059 		JBrowse link
G FUBP1 far upstream element binding protein 1 ISO RGD PMID:23797733 RGD:13673879 NCBI chr 6:68,923,215...68,963,766 JBrowse link
G GNAL G protein subunit alpha L ISO RGD PMID:29215295 RGD:13513923 NCBI chr 7:77,378,134...77,521,215
Ensembl chr 7:77,413,986...77,521,042 		JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 ISO protein:increased phosphorylation:central amygdaloid nucleus (rat) RGD PMID:30638118 RGD:405101698 NCBI chr 4:55,801,269...56,103,383
Ensembl chr 4:55,803,296...56,103,669 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr20:50,818,715...50,827,914
Ensembl chr20:50,818,715...50,827,914 		JBrowse link
G IL1B interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G ITGB1 integrin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr 2:3,728,472...3,757,696
Ensembl chr 2:3,670,596...3,756,961 		JBrowse link
G LAMA1 laminin subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr 7:73,309,383...73,438,543
Ensembl chr 7:73,309,388...73,448,151 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 ISO protein:increased expression:hippocampus: RGD PMID:28365875 RGD:13703062 NCBI chr  X:92,405,946...92,444,527
Ensembl chr  X:92,407,950...92,444,765 		JBrowse link
G LCN2 lipocalin 2 ISO RGD PMID:31539545 RGD:126781751 NCBI chr 9:55,328,118...55,342,535
Ensembl chr 9:55,328,133...55,332,038 		JBrowse link
G MAPT microtubule associated protein tau treatment ISO RGD PMID:25771151 PMID:26484783 PMID:26729399 PMID:28412141 RGD:13800902 RGD:13800909 RGD:13800912 RGD:13800917 NCBI chr 9:9,572,174...9,674,082
Ensembl chr 9:9,570,557...9,674,349 		JBrowse link
G METTL14 methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit ISO mRNA:decreased expression:cerebral cortex RGD PMID:31992337 RGD:329901857 NCBI chr32:37,653,163...37,679,577
Ensembl chr32:37,653,035...37,678,398 		JBrowse link
G MIR155 microRNA mir-155 ISO RGD PMID:28804446 RGD:25314324 NCBI chr31:21,078,768...21,078,828
Ensembl chr31:21,078,758...21,078,833 		JBrowse link
G MMP2 matrix metallopeptidase 2 ISO protein:increased expression:cerebral cortex RGD PMID:27614125 RGD:329961568 NCBI chr 2:60,471,092...60,492,991
Ensembl chr 2:60,471,257...60,494,113 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293 		JBrowse link
G MPO myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr 9:32,927,483...32,938,007
Ensembl chr 9:32,927,483...32,937,820 		JBrowse link
G NCSTN nicastrin ISO RGD PMID:18240300 RGD:13801189 NCBI chr38:21,878,071...21,891,362
Ensembl chr38:21,685,868...21,892,097 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO protein:increased expression:brain: RGD PMID:30855558 RGD:26884463 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524 		JBrowse link
G NGF nerve growth factor treatment ISO RGD PMID:26285082 RGD:402463964 NCBI chr17:52,900,647...52,901,607
Ensembl chr17:52,900,647...52,901,607 		JBrowse link
G NMNAT1 nicotinamide nucleotide adenylyltransferase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:27822499 NCBI chr 5:63,122,379...63,152,078
Ensembl chr 5:63,122,498...63,151,661 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr 9:42,171,821...42,210,217
Ensembl chr 9:42,171,821...42,208,588 		JBrowse link
G NOX1 NADPH oxidase 1 ISO protein:increased expression:cerebral cortex RGD PMID:27614125 RGD:329961568 NCBI chr  X:74,784,627...74,811,796
Ensembl chr  X:74,785,168...74,811,698 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO protein:increased phosphorylation:amygdala
mRNA:decreased expression:hippocampus, hypothalamus		 RGD PMID:30638118 PMID:36637480 RGD:405101698 RGD:408364984 NCBI chr 2:38,124,568...38,242,510
Ensembl chr 2:38,123,190...38,240,755 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO mRNA:increased expression:dentate gyrus RGD PMID:10925157 RGD:596936229 NCBI chr 1:74,447,927...74,777,910
Ensembl chr 1:74,449,060...74,777,032 		JBrowse link
G OCLN occludin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 NCBI chr 2:54,500,299...54,545,430
Ensembl chr 2:54,500,299...54,545,430 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829224 PMID:28642177 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127 		JBrowse link
G PDE10A phosphodiesterase 10A ISO RGD PMID:29215295 RGD:13513923 NCBI chr 1:53,457,781...54,049,735
Ensembl chr 1:53,462,979...53,801,966 		JBrowse link
G PDYN prodynorphin ISO mRNA:increased expression:hippocampus RGD PMID:12626770 RGD:633616 NCBI chr24:19,043,955...19,057,413
Ensembl chr24:19,053,870...19,056,364 		JBrowse link
G PHACTR1 phosphatase and actin regulator 1 treatment ISO RGD PMID:36571365 RGD:401901253 NCBI chr35:12,233,152...12,745,031
Ensembl chr35:12,491,067...12,741,754 		JBrowse link
G PPP3R1 protein phosphatase 3 regulatory subunit B, alpha ISO RGD PMID:20713027 RGD:13830881 NCBI chr10:67,242,552...67,308,469
Ensembl chr10:67,244,329...67,275,487 		JBrowse link
G PPP3R2 protein phosphatase 3 regulatory subunit B, beta ISO RGD PMID:20713027 RGD:13830881 NCBI chr11:58,295,237...58,295,942 JBrowse link
G PSEN1 presenilin 1 ISO RGD PMID:18240300 RGD:13801189 NCBI chr 8:46,495,551...46,569,532
Ensembl chr 8:46,495,624...46,569,532 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25668593 PMID:28642177 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875 		JBrowse link
G SOX2 SRY-box transcription factor 2 treatment ISO RGD PMID:26296359 RGD:597538582 NCBI chr34:14,853,000...14,855,153 JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28642177 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425 		JBrowse link
G TP53 tumor protein p53 treatment ISO RGD PMID:27553877 RGD:14995939 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
G UBE4B ubiquitination factor E4B ISO CTD Direct Evidence: therapeutic CTD PMID:27822499 NCBI chr 5:63,214,846...63,339,218
Ensembl chr 5:63,215,470...63,338,215 		JBrowse link
G WNT3A Wnt family member 3A treatment ISO RGD PMID:26296359 RGD:597538582 NCBI chr14:864,393...899,698
Ensembl chr14:863,424...896,412 		JBrowse link
Traumatic Intracranial Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F7 coagulation factor VII ISO CTD Direct Evidence: therapeutic CTD PMID:20370756 NCBI chr22:60,572,459...60,582,743
Ensembl chr22:60,571,822...60,597,024 		JBrowse link
Traumatic Subarachnoid Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 treatment ISO RGD PMID:18854840 RGD:2325137 NCBI chr21:39,963,001...40,037,040
Ensembl chr21:39,962,947...40,036,981 		JBrowse link
Trigeminal Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 ISO RGD PMID:22977862 RGD:8547771 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
Vestibulocochlear Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 ISO mRNA:increased expression:Vestibulocochlear nerve: RGD PMID:22178544 RGD:8548530 NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15758
    Wounds and Injuries 965
      Nervous System Trauma 592
        Craniocerebral Trauma 362
          Brain Injuries + 289
          Cerebrospinal Fluid Leak + 0
          Closed Head Injuries + 10
          Cranial Nerve Injuries + 83
          Facial Injuries + 13
          Penetrating Head Injuries 5
          Post-Head Injury Coma 1
          Skull Fractures + 4
          Traumatic Intracranial Hemorrhage + 8
Path 2
Term Annotations click to browse term
  disease 15758
    disease of anatomical entity 15377
      nervous system disease 13504
        Nervous System Trauma 592
          Craniocerebral Trauma 362
            Brain Injuries + 289
            Cerebrospinal Fluid Leak + 0
            Closed Head Injuries + 10
            Cranial Nerve Injuries + 83
            Facial Injuries + 13
            Penetrating Head Injuries 5
            Post-Head Injury Coma 1
            Skull Fractures + 4
            Traumatic Intracranial Hemorrhage + 8
paths to the root