RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Craniocerebral Trauma
Accession: DOID:9007621
browse the term
Definition: Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage.
Synonyms: exact_synonym: Craniocerebral Injuries; Craniocerebral Injury; Craniocerebral Traumas; Crushing Skull Injuries; Crushing Skull Injury; Forehead Trauma; Forehead Traumas; Frontal Region Trauma; Frontal Region Traumas; Head Injuries; Head Injury; Head Trauma; Head Traumas; Minor Head Injuries; Minor Head Injury; Multiple Head Injuries; Multiple Head Injury; Occipital Region Trauma; Occipital Region Traumas; Occipital Trauma; Occipital Traumas; Open Head Injuries; Open Head Injury; Parietal Region Trauma; Parietal Region Traumas; Superficial Head Injuries; Superficial Head Injury; Temporal Region Trauma; Temporal Region Traumas
primary_id: MESH:D006259 ; RDO:0005059
xref: EFO:0009505
GViewer not supported for the selected species.
G
Adnp
activity dependent neuroprotector homeobox
ISO
RGD
PMID:11123362
RGD:2312784
NCBI chrNW_004955445:7,498,223...7,530,828
Ensembl chrNW_004955445:7,492,257...7,531,862
G
Il1a
interleukin 1 alpha
ISO
protein:increased expression:microglial cell
RGD
PMID:7830934
RGD:10045949
NCBI chrNW_004955470:1,527,710...1,538,418
Ensembl chrNW_004955470:1,527,674...1,538,466
G
Postn
periostin
ISO
RGD
PMID:17878602
RGD:10041014
NCBI chrNW_004955431:8,510,646...8,544,901
Ensembl chrNW_004955431:8,510,624...8,544,971
G
Serpinc1
serpin family C member 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8810955
NCBI chrNW_004955406:14,024,183...14,036,206
Ensembl chrNW_004955406:14,024,313...14,035,948
G
Epo
erythropoietin
treatment
ISO
RGD
PMID:23415790
RGD:10401075
NCBI chrNW_004955573:203,875...206,078
Ensembl chrNW_004955573:203,441...206,355
G
F7
coagulation factor VII
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:12503044
NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665
G
Kcnn4
potassium calcium-activated channel subfamily N member 4
treatment
ISO
RGD
PMID:15379997
RGD:329969897
NCBI chrNW_004955555:1,493,600...1,509,113
Ensembl chrNW_004955555:1,490,052...1,509,113
G
Cfl1
cofilin 1
treatment
ISO
RGD
PMID:25708984
RGD:12738361
NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571
G
Drd2
dopamine receptor D2
ISO
RGD
PMID:26448536
RGD:13506960
NCBI chrNW_004955412:15,054,255...15,114,558
Ensembl chrNW_004955412:15,054,038...15,114,573
G
Drd3
dopamine receptor D3
ISO
RGD
PMID:26448536
RGD:13506960
NCBI chrNW_004955427:14,219,519...14,252,178
Ensembl chrNW_004955427:14,219,594...14,252,178
G
Drd4
dopamine receptor D4
ISO
RGD
PMID:26448536
RGD:13506960
NCBI chrNW_004955476:11,424,347...11,426,962
Ensembl chrNW_004955476:11,424,411...11,426,960
G
Il6
interleukin 6
treatment
ISO
RGD
PMID:27113205
RGD:11062140
NCBI chrNW_004955410:25,079,835...25,084,390
G
C3
complement C3
ameliorates
ISO
RGD
PMID:31654641
RGD:408418727
NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697
G
Casp3
caspase 3
treatment
ISO
RGD
PMID:28140659
RGD:13782305
NCBI chrNW_004955403:24,315,712...24,326,271
G
Casp8
caspase 8
treatment
ISO
RGD
PMID:28140659
RGD:13782305
NCBI chrNW_004955403:322,082...348,591
Ensembl chrNW_004955403:322,555...347,053
G
Il1b
interleukin 1 beta
treatment
ISO
RGD
PMID:31654641
RGD:408418727
NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
G
Tnf
tumor necrosis factor
treatment
ISO
RGD
PMID:31654641
RGD:408418727
NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
G
Abcc8
ATP binding cassette subfamily C member 8
treatment
ISO
RGD
PMID:21107131
RGD:12791995
NCBI chrNW_004955414:32,216,243...32,289,028
Ensembl chrNW_004955414:32,216,196...32,289,053
G
Acan
aggrecan
ISO
mRNA:increased expression:fascia dentata (rat)
RGD
PMID:18511192
RGD:2315807
NCBI chrNW_004955416:16,125,536...16,186,046
G
Actr2
actin related protein 2
ISO
mRNA, protein:decreased expression:hippocampus (rat)
RGD
PMID:22120305
RGD:11530046
NCBI chrNW_004955424:19,293,949...19,333,170
Ensembl chrNW_004955424:19,293,949...19,333,170
G
Adcyap1
adenylate cyclase activating polypeptide 1
ISO
RGD
PMID:16689670
RGD:2325298
NCBI chrNW_004955402:9,091,927...9,099,803
Ensembl chrNW_004955402:9,091,725...9,099,803
G
Adra1a
adrenoceptor alpha 1A
ISO
mRNA:increased expression:frontal cortex
RGD
PMID:20974230
RGD:5688366
NCBI chrNW_004955403:49,394,173...49,485,881
Ensembl chrNW_004955403:49,399,127...49,485,934
G
Ager
advanced glycosylation end-product specific receptor
ISO
protein:increased expression:brain (rat)
RGD
PMID:22491548 PMID:22915134 PMID:24859607
RGD:7245513 RGD:7245557 RGD:8696001
NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
G
Aif1
allograft inflammatory factor 1
ISO
protein:increased expression:cerebral cortex (rat)
RGD
PMID:19520144
RGD:2313020
NCBI chrNW_004955437:157,509...158,919
Ensembl chrNW_004955437:157,509...158,919
G
Aifm1
apoptosis inducing factor mitochondria associated 1
ISO
protein:increased expression:nucleus:
RGD
PMID:12091479
RGD:10053567
NCBI chrNW_004955473:4,891,955...4,925,705
Ensembl chrNW_004955473:4,891,955...4,926,428
G
Akt1
AKT serine/threonine kinase 1
ISO
protein:increased phosphorylation:brain, neuron
RGD
PMID:16234845
RGD:5509090
NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904
G
Alb
albumin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:7909931 PMID:17188501
NCBI chrNW_004955447:9,327...21,212
G
Ambp
alpha-1-microglobulin/bikunin precursor
ISO
protein:increased expression:urine
RGD
PMID:14592616
RGD:6904155
NCBI chrNW_004955419:13,478,904...13,492,329
Ensembl chrNW_004955419:13,478,552...13,492,327
G
Ank3
ankyrin 3
ISO
RGD
PMID:20557305
RGD:6767288
NCBI chrNW_004955425:13,522,233...13,851,286
G
Anp32a
acidic nuclear phosphoprotein 32 family member A
ISO
RGD
PMID:24385964
RGD:10401136
NCBI chrNW_004955450:7,449,368...7,484,524
G
Apaf1
apoptotic peptidase activating factor 1
ISO
protein:increased expression:cerebral cortex
RGD
PMID:11567033
RGD:2325751
NCBI chrNW_004955405:34,619,780...34,693,616
Ensembl chrNW_004955405:34,623,267...34,693,677
G
Apbb1
amyloid beta precursor protein binding family B member 1
ISO
mRNA:increased expression:brain
RGD
PMID:12707777
RGD:2301208
NCBI chrNW_004955414:22,121,867...22,137,849
Ensembl chrNW_004955414:22,117,470...22,137,849
G
Apex1
apurinic/apyrimidinic endodeoxyribonuclease 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11447995
NCBI chrNW_004955550:1,273,170...1,275,843
Ensembl chrNW_004955550:1,273,284...1,279,743
G
Apod
apolipoprotein D
ISO
mRNA, protein:increased expression:cerebral cortex, glia cell, neuron
RGD
PMID:10501208
RGD:2311202
NCBI chrNW_004955420:13,553,254...13,570,357
Ensembl chrNW_004955420:13,553,058...13,573,690
G
App
amyloid beta precursor protein
ISO
protein:increased expression:hippocampus
RGD
PMID:16300758
RGD:10054281
NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268
G
Aqp4
aquaporin 4
ISO
protein:increased expression:cerebral cortex
RGD
PMID:21083433 PMID:21488209
RGD:5148014 RGD:5148034
NCBI chrNW_004955772:1,160...10,709
Ensembl chrNW_004955772:1,159...10,709
G
Asic1
acid sensing ion channel subunit 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21307247
NCBI chrNW_004955547:635,714...658,541
Ensembl chrNW_004955547:635,638...658,541
G
Astn1
astrotactin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:14499481
NCBI chrNW_004955406:16,445,738...16,742,185
Ensembl chrNW_004955406:16,445,495...16,742,295
G
Atg12
autophagy related 12
ISO
protein:altered localization:brain
RGD
PMID:18059433
RGD:2301217
NCBI chrNW_004955408:35,607,541...35,620,878
Ensembl chrNW_004955408:35,607,541...35,620,878
G
Atp5pd
ATP synthase peripheral stalk subunit d
treatment
ISO
RGD
PMID:26813465
RGD:13800884
NCBI chrNW_004955553:1,893,767...1,897,175
Ensembl chrNW_004955553:1,892,670...1,897,175
G
Avpr1a
arginine vasopressin receptor 1A
ISO
mRNA:increased expression:cerebral cortex
RGD
PMID:17244947
RGD:2300372
NCBI chrNW_004955458:10,245,325...10,253,209
Ensembl chrNW_004955458:10,245,111...10,253,209
G
Bad
BCL2 associated agonist of cell death
ISO
mRNA, protein:increased expression:cerebral cortex
RGD
PMID:15941375
RGD:2292694
NCBI chrNW_004955422:20,795,585...20,809,039
Ensembl chrNW_004955422:20,795,676...20,809,245
G
Bax
BCL2 associated X, apoptosis regulator
treatment
ISO
RGD
PMID:20888848
RGD:10054247
NCBI chrNW_004955559:1,695,960...1,700,246
Ensembl chrNW_004955559:1,695,960...1,700,244
G
Bcat1
branched chain amino acid transaminase 1
ISO
Protein:increased expression:neurons
RGD
PMID:10686349
RGD:631308
NCBI chrNW_004955413:19,975,395...20,087,656
Ensembl chrNW_004955413:19,981,328...20,087,638
G
Bcl2
BCL2 apoptosis regulator
treatment
ISO
RGD
PMID:18093155 PMID:20888848
RGD:10054247 RGD:2293059
NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485
G
Bdnf
brain derived neurotrophic factor
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
RGD CTD
PMID:15500971 PMID:20544832 PMID:21269288
RGD:4891136
NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
G
Becn1
beclin 1
ISO
protein:increased expression:brain CTD Direct Evidence: therapeutic protein:increased expression:hippocampus protein:increased expression:neuron, astrocyte
RGD CTD
PMID:16874043 PMID:18500386 PMID:24221859 PMID:34929507
RGD:11558018 RGD:6483098 RGD:6483314
NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730
G
Bmp6
bone morphogenetic protein 6
ISO
protein:increased expression:brain, astrocyte, neuron
RGD
PMID:16388909
RGD:2289020
NCBI chrNW_004955465:6,053,600...6,201,254
Ensembl chrNW_004955465:6,054,931...6,200,377
G
Bmpr2
bone morphogenetic protein receptor type 2
ISO
mRNA:increased expression:dentate gyrus, neuron
RGD
PMID:9080432
RGD:5129488
NCBI chrNW_004955457:12,235,780...12,315,680
Ensembl chrNW_004955457:12,235,780...12,316,727
G
Bysl
bystin like
ISO
mRNA, protein:increased expression:substantia nigra, striatum (rat)
RGD
PMID:15305856
RGD:2316201
NCBI chrNW_004955437:8,257,081...8,266,627
Ensembl chrNW_004955437:8,257,081...8,266,875
G
C1qa
complement C1q A chain
ISO
RGD
PMID:23808389
RGD:10054313
NCBI chrNW_004955452:2,753,362...2,756,220
Ensembl chrNW_004955452:2,752,970...2,756,488
G
C3
complement C3
ISO
RGD
PMID:23808389
RGD:10054313
NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697
G
Cask
calcium/calmodulin dependent serine protein kinase
ISO
RGD
PMID:25089700
RGD:11576302
NCBI chrNW_004955565:879,560...1,242,727
Ensembl chrNW_004955565:879,830...1,237,692
G
Casp3
caspase 3
treatment
ISO
RGD
PMID:20888848
RGD:10054247
NCBI chrNW_004955403:24,315,712...24,326,271
G
Casp8
caspase 8
ISO
protein:altered localization
RGD
PMID:15590916
RGD:1624191
NCBI chrNW_004955403:322,082...348,591
Ensembl chrNW_004955403:322,555...347,053
G
Cast
calpastatin
severity
ISO
mRNA:increased expression:cerebral cortex
RGD
PMID:15307896
RGD:5509821
NCBI chrNW_004955418:15,859,951...15,974,141
Ensembl chrNW_004955418:15,862,729...15,916,169
G
Ccl20
C-C motif chemokine ligand 20
treatment
ISO
RGD
PMID:22040257
RGD:7483630
NCBI chrNW_004955453:6,846,625...6,850,007
Ensembl chrNW_004955453:6,846,549...6,850,031
G
Cd14
CD14 molecule
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004955418:73,736...75,345
Ensembl chrNW_004955418:73,897...75,224
G
Cd40
CD40 molecule
treatment
ISO
RGD
PMID:23924471
RGD:7248749
NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093
G
Cd40lg
CD40 ligand
treatment
ISO
RGD
PMID:11755016 PMID:25972624
RGD:11344972 RGD:8547803
NCBI chrNW_004955489:8,465,571...8,477,714
Ensembl chrNW_004955489:8,465,164...8,477,746
G
Cdkn1a
cyclin dependent kinase inhibitor 1A
ISO
protein:increased expression:nucleus:
RGD
PMID:9914434
RGD:8662346
NCBI chrNW_004955437:6,254,638...6,261,278
Ensembl chrNW_004955437:6,254,309...6,261,479
G
Cdkn1b
cyclin dependent kinase inhibitor 1B
ISO
protein:decreased expression:cerebral cortex
RGD
PMID:21728064
RGD:10045359
NCBI chrNW_004955413:9,615,542...9,620,542
Ensembl chrNW_004955413:9,615,542...9,620,542
G
Cebpa
CCAAT enhancer binding protein alpha
ISO
mRNA, protein:increased expression:cerebral cortex (mouse)
RGD
PMID:19833158
RGD:10401206
NCBI chrNW_004955468:3,046,544...3,049,217
Ensembl chrNW_004955468:3,047,931...3,049,080
G
Cebpb
CCAAT enhancer binding protein beta
ISO
mRNA, protein:increased expression:cerebral cortex (mouse) CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:19833158 PMID:21549006
RGD:10401206
NCBI chrNW_004955445:8,060,432...8,061,289
G
Cfb
complement factor B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17474994
NCBI chrNW_004955437:461,235...466,908
Ensembl chrNW_004955437:461,235...470,464
G
Chrm2
cholinergic receptor muscarinic 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955494:5,845,581...5,975,614
Ensembl chrNW_004955494:5,847,156...5,848,556
G
Chrna7
cholinergic receptor nicotinic alpha 7 subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955416:30,687,518...30,798,700
Ensembl chrNW_004955416:30,687,478...30,798,700
G
Clec4e
C-type lectin domain family 4 member E
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004955413:5,256,523...5,261,385
Ensembl chrNW_004955413:5,256,440...5,262,938
G
Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
ISO
protein:increased expression:hippocampus
RGD
PMID:20215974
RGD:6483336
NCBI chrNW_004955451:16,115,137...16,119,261
Ensembl chrNW_004955451:16,114,454...16,118,622
G
Comt
catechol-O-methyltransferase
ISO
protein:increased expression:hippocampus
RGD
PMID:17240060
RGD:2289740
NCBI chrNW_004955442:18,130,282...18,152,153
Ensembl chrNW_004955442:18,130,987...18,137,412
G
Csf2
colony stimulating factor 2
disease_progression
ISO
RGD
PMID:21515263
RGD:5686795
NCBI chrNW_004955408:3,452,009...3,454,255
Ensembl chrNW_004955408:3,451,965...3,454,312
G
Csf3
colony stimulating factor 3
treatment
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:21549006 PMID:24239694
RGD:11039431
NCBI chrNW_004955451:14,688,181...14,690,126
Ensembl chrNW_004955451:14,688,181...14,690,126
G
Cspg4
chondroitin sulfate proteoglycan 4
ISO
protein:altered expression:cerebral cortex
RGD
PMID:19473238
RGD:5686860
NCBI chrNW_004955450:2,631,310...2,663,118
Ensembl chrNW_004955450:2,631,327...2,662,269
G
Cul5
cullin 5
ISO
mRNA, protein:decreased expression:cerebral cortex, hippocampus
RGD
PMID:17010517
RGD:2301432
NCBI chrNW_004955412:10,266,072...10,336,156
Ensembl chrNW_004955412:10,256,381...10,336,156
G
Cxcl10
C-X-C motif chemokine ligand 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004955433:748,392...750,890
Ensembl chrNW_004955433:748,284...750,927
G
Dab2
DAB adaptor protein 2
ISO
RGD
PMID:15774263
RGD:7243841
NCBI chrNW_004955426:23,852,752...23,883,030
G
Dnmt1
DNA methyltransferase 1
ISO
RGD
PMID:19429151
RGD:9588608
NCBI chrNW_004955495:1,465,529...1,505,379
Ensembl chrNW_004955495:1,465,480...1,505,462
G
Dpysl2
dihydropyrimidinase like 2
ISO
protein:increased degradation:cerebral cortex, hippocampus
RGD
PMID:17402852
RGD:2303056
NCBI chrNW_004955403:49,188,259...49,306,916
Ensembl chrNW_004955403:49,188,205...49,307,810
G
Drd2
dopamine receptor D2
ISO
RGD
PMID:18509630
RGD:2311580
NCBI chrNW_004955412:15,054,255...15,114,558
Ensembl chrNW_004955412:15,054,038...15,114,573
G
Dusp5
dual specificity phosphatase 5
ISO
mRNA:increased expression:cerebral cortex
RGD
PMID:12503083
RGD:2317873
NCBI chrNW_004955485:914,250...927,640
Ensembl chrNW_004955485:915,353...927,460
G
Eif2s1
eukaryotic translation initiation factor 2 subunit alpha
ISO
RGD
PMID:11526986
RGD:10395358
NCBI chrNW_004955466:2,838,785...2,855,443
Ensembl chrNW_004955466:2,838,785...2,855,172
G
Elk1
ETS transcription factor ELK1
ISO
RGD
PMID:15362724
RGD:7488910
NCBI chrNW_004955516:431,081...444,871
Ensembl chrNW_004955516:430,775...444,871
G
Eno2
enolase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:34533065
NCBI chrNW_004955413:4,498,625...4,506,769
Ensembl chrNW_004955413:4,498,625...4,506,769
G
Epas1
endothelial PAS domain protein 1
treatment
ISO
RGD
PMID:22960363
RGD:10395371
NCBI chrNW_004955441:13,244,626...13,328,220
Ensembl chrNW_004955441:13,244,626...13,328,369
G
Epha4
EPH receptor A4
ISO
protein:increased expression, increased activity:astrocyte
RGD
PMID:22318127
RGD:5688763
NCBI chrNW_004955453:12,099,800...12,240,199
Ensembl chrNW_004955453:12,099,757...12,240,199
G
Ephx2
epoxide hydrolase 2
ISO
RGD
PMID:21075124
RGD:5688356
NCBI chrNW_004955403:49,999,563...50,038,800
Ensembl chrNW_004955403:49,999,563...50,041,572
G
Epo
erythropoietin
treatment
ISO
mRNA:increased expression:brain: CTD Direct Evidence: therapeutic
RGD CTD
PMID:18093155 PMID:20833152 PMID:23063952
RGD:10401061 RGD:2293059
NCBI chrNW_004955573:203,875...206,078
Ensembl chrNW_004955573:203,441...206,355
G
Epor
erythropoietin receptor
ISO
mRNA:increased expression:brain:
RGD
PMID:18093155
RGD:2293059
NCBI chrNW_004955495:2,293,587...2,299,302
Ensembl chrNW_004955495:2,293,540...2,298,715
G
F2
coagulation factor II, thrombin
severity
ISO
RGD
PMID:21355766
RGD:5147766
NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517
G
Fas
Fas cell surface death receptor
ISO
associated with Hyperoxia mRNA:increased expression:hippocampus
RGD
PMID:16078565 PMID:19107989
RGD:1600354 RGD:8662854
NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455
G
Fgf2
fibroblast growth factor 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21269288
NCBI chrNW_004955428:17,840,554...17,894,779
Ensembl chrNW_004955428:17,840,628...17,894,773
G
Fmr1
Fragile X messenger ribonucleoprotein 1
ISO
protein:altered localization:hippocampus (rat)
RGD
PMID:16510718
RGD:11667962
NCBI chrNW_004955498:566,741...594,837
Ensembl chrNW_004955498:566,688...595,360
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:9630518
NCBI chrNW_004955523:307,181...310,728
Ensembl chrNW_004955523:305,728...310,728
G
Foxp1
forkhead box P1
treatment
ISO
RGD
PMID:26842647
RGD:11561903
NCBI chrNW_004955421:16,595,445...17,075,923
Ensembl chrNW_004955421:16,595,471...17,075,923
G
G6pd
glucose-6-phosphate dehydrogenase
ISO
protein:decreased expression:hippocampus
RGD
PMID:18501200
RGD:2307353
NCBI chrNW_004955580:1,045,294...1,058,129
Ensembl chrNW_004955580:1,045,294...1,057,083
G
Gabrb3
gamma-aminobutyric acid type A receptor subunit beta3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955533:2,879,437...2,938,952
Ensembl chrNW_004955533:2,573,599...2,938,952
G
Gabrg3
gamma-aminobutyric acid type A receptor subunit gamma3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955533:1,962,175...2,495,877
Ensembl chrNW_004955533:1,962,273...2,495,876
G
Gdnf
glial cell derived neurotrophic factor
ISO
mRNA:increased expression:brain
RGD
PMID:18501516
RGD:2324932
NCBI chrNW_004955426:22,386,613...22,412,324
Ensembl chrNW_004955426:22,386,450...22,412,324
G
Gja1
gap junction protein alpha 1
treatment
ISO
RGD
PMID:23485053
RGD:8662424
NCBI chrNW_004955436:3,612,533...3,618,095
Ensembl chrNW_004955436:3,612,533...3,618,095
G
Gja5
gap junction protein alpha 5
ISO
protein:increased expression:cerebral artery
RGD
PMID:21895483
RGD:7207391
NCBI chrNW_004955568:635,319...652,692
Ensembl chrNW_004955568:635,042...653,349
G
Gpx1
glutathione peroxidase 1
ISO
mRNA:decreased expression:hippocampus, neuron
RGD
PMID:15791111
RGD:2306624
NCBI chrNW_004955532:1,298,336...1,298,830
G
Grm8
glutamate metabotropic receptor 8
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955479:7,520,537...8,279,942
Ensembl chrNW_004955479:7,520,396...8,279,755
G
Gsk3b
glycogen synthase kinase 3 beta
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:22643085 PMID:24675465
RGD:10045646
NCBI chrNW_004955427:19,489,972...19,671,137
Ensembl chrNW_004955427:19,495,422...19,671,137
G
Gsn
gelsolin
ISO
RGD
PMID:14588109
RGD:1599864
NCBI chrNW_004955419:6,682,202...6,733,361
Ensembl chrNW_004955419:6,682,058...6,733,361
G
Hcn1
hyperpolarization activated cyclic nucleotide gated potassium channel 1
ISO
mRNA,protein:decreased expression:hippocampus:
RGD
PMID:11726545
RGD:9686434
NCBI chrNW_004955446:17,146,915...17,457,843
Ensembl chrNW_004955446:17,151,311...17,457,888
G
Hmgb1
high mobility group box 1
treatment
ISO
RGD
PMID:22915134
RGD:7245513
NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
ISO
RGD
PMID:18562561
RGD:5508455
NCBI chrNW_004955425:25,362,165...25,380,611
Ensembl chrNW_004955425:25,359,884...25,380,745
G
Hmox1
heme oxygenase 1
ISO
RGD
PMID:23470432
RGD:10755702
NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979
G
Hspa4
heat shock protein family A (Hsp70) member 4
ISO
protein:increased expression:cerebral white matter (rat)
RGD
PMID:22067617
RGD:5688785
NCBI chrNW_004955408:4,379,825...4,422,710
Ensembl chrNW_004955408:4,379,825...4,423,381
G
Hspb1
heat shock protein family B (small) member 1
ISO
RGD
PMID:11746764
RGD:6480530
NCBI chrNW_004955844:8,094...9,565
Ensembl chrNW_004955844:7,790...10,004
G
Htr7
5-hydroxytryptamine receptor 7
ISO
RGD
PMID:22465320
RGD:6482178
NCBI chrNW_004955425:2,321,420...2,420,420
Ensembl chrNW_004955425:2,321,420...2,420,530
G
Icam1
intercellular adhesion molecule 1
ISO
protein:increased expression:brain:
RGD
PMID:16230799
RGD:11522716
NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
G
Igf1
insulin like growth factor 1
treatment
ISO
human protein in a rat model
RGD
PMID:9344566
RGD:12904928
NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
G
Igf2
insulin like growth factor 2
ISO
mRNA:decreased expression:brain
RGD
PMID:11123717
RGD:5509972
NCBI chrNW_004955422:13,880,525...13,907,963
Ensembl chrNW_004955422:13,880,471...13,888,566
G
Il10
interleukin 10
treatment severity
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:21549006 PMID:23075771 PMID:23971414
RGD:7364822 RGD:7364983
NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
G
Il12rb2
interleukin 12 receptor subunit beta 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955423:23,774,557...23,806,744
G
Il13ra2
interleukin 13 receptor subunit alpha 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955490:708,144...758,195
Ensembl chrNW_004955490:709,446...758,272
G
Il16
interleukin 16
ISO
RGD
PMID:17983426
RGD:5024939
NCBI chrNW_004955416:11,876,317...11,987,548
G
Il17rd
interleukin 17 receptor D
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955430:6,842,756...6,873,195
Ensembl chrNW_004955430:6,848,820...6,898,704
G
Il18
interleukin 18
severity
ISO
mRNA, protein:increased expression:brain
RGD
PMID:17188500
RGD:2315917
NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634
G
Il18r1
interleukin 18 receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955470:7,854,995...7,887,810
Ensembl chrNW_004955470:7,854,988...7,887,883
G
Il1a
interleukin 1 alpha
ISO
mRNA, protein:increased expression:cerebral cortex CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:16024175 PMID:21549006
RGD:2311098
NCBI chrNW_004955470:1,527,710...1,538,418
Ensembl chrNW_004955470:1,527,674...1,538,466
G
Il1b
interleukin 1 beta
ISO
protein:increased expression:brain, cerebrospinal fluid mRNA, protein:increased expression:cerebral cortex mRNA, protein:increased expression:brain CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:16024175 PMID:17612572 PMID:19800810 PMID:21549006 PMID:22503903
RGD:1626652 RGD:2311098 RGD:6482651
NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
G
Il1r1
interleukin 1 receptor type 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004955470:7,685,498...7,703,374
G
Il1rn
interleukin 1 receptor antagonist
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:25665855
NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471
G
Il2
interleukin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265
G
Il31ra
interleukin 31 receptor A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955446:11,857,882...11,963,867
Ensembl chrNW_004955446:11,857,862...11,961,147
G
Il4
interleukin 4
ISO
protein:decreased expression:plasma
RGD
PMID:24519543
RGD:10402802
NCBI chrNW_004955408:4,058,052...4,065,999
G
Il5
interleukin 5
treatment
ISO
RGD
PMID:24530657 PMID:24602693
RGD:11522766 RGD:11522770
NCBI chrNW_004955408:3,937,128...3,951,784
Ensembl chrNW_004955408:3,937,894...3,939,358
G
Il6
interleukin 6
ISO
protein:increased expression:cerebrospinal fluid (rat) CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:10027774 PMID:19800810 PMID:21549006 PMID:23159883
RGD:11049549
NCBI chrNW_004955410:25,079,835...25,084,390
G
Il7
interleukin 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955444:2,365,077...2,400,953
G
Il9r
interleukin 9 receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955442:17,115,207...17,128,899
Ensembl chrNW_004955442:17,117,429...17,127,451
G
Irf1
interferon regulatory factor 1
ISO
mRNA:increased expression:cerebral cortex CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:12503083 PMID:21549006
RGD:2317873
NCBI chrNW_004955408:3,882,282...3,887,965
Ensembl chrNW_004955408:3,880,155...3,887,973
G
Jak2
Janus kinase 2
ISO
RGD
PMID:21596098
RGD:6483023
NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004955464:1,107,598...1,110,326
G
Kcnj10
potassium inwardly rectifying channel subfamily J member 10
ISO
RGD
PMID:20861444
RGD:8662901
NCBI chrNW_004955468:11,828,525...11,860,365
Ensembl chrNW_004955468:11,828,525...11,860,365
G
Kdr
kinase insert domain receptor
ISO
protein:increased expression:cerebral cortex
RGD
PMID:19733172 PMID:21307798
RGD:5684382 RGD:5684402
NCBI chrNW_004955447:15,810,816...15,851,702
Ensembl chrNW_004955447:15,810,815...15,853,583
G
Lep
leptin
ISO
RGD
PMID:21276361
RGD:5128517
NCBI chrNW_004955479:9,266,604...9,276,568
Ensembl chrNW_004955479:9,274,516...9,279,472
G
LOC102014960
cholesterol side-chain cleavage enzyme, mitochondrial
ISO
mRNA:increased expression:hindbrain
RGD
PMID:16329132
RGD:1599699
NCBI chrNW_004955450:3,433,310...3,484,462
Ensembl chrNW_004955450:3,474,491...3,484,232
G
LOC102027549
serotransferrin
ISO
RGD
PMID:22538758
RGD:7244386
NCBI chrNW_004955501:4,801,710...4,832,025
Ensembl chrNW_004955501:4,801,885...4,831,910
G
Lsg1
large 60S subunit nuclear export GTPase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:14499481
NCBI chrNW_004955420:14,216,430...14,244,289
G
Ly86
lymphocyte antigen 86
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004955465:7,106,182...7,168,046
Ensembl chrNW_004955465:7,102,385...7,168,595
G
Mag
myelin associated glycoprotein
susceptibility
ISO
RGD
PMID:17156367
RGD:9685230
NCBI chrNW_004955468:4,584,068...4,598,772
Ensembl chrNW_004955468:4,584,162...4,598,914
G
Map1b
microtubule associated protein 1B
ISO
protein:increased expression, increased phosphorylation:brain
RGD
PMID:10906717
RGD:2304029
NCBI chrNW_004955575:914,607...1,020,971
Ensembl chrNW_004955575:913,723...1,021,028
G
Map1lc3a
microtubule associated protein 1 light chain 3 alpha
ISO
RGD
PMID:24221859
RGD:11558018
NCBI chrNW_004955422:26,774,466...26,776,024
Ensembl chrNW_004955422:26,774,922...26,775,884
G
Map2
microtubule associated protein 2
ISO
protein:decreased expression:cerebral cortex, neuron
RGD
PMID:20568963 PMID:21401443
RGD:6483087 RGD:6483089
NCBI chrNW_004955457:5,678,826...5,816,114
Ensembl chrNW_004955457:5,678,436...5,875,024
G
Map3k7
mitogen-activated protein kinase kinase kinase 7
treatment
ISO
associated with Subarachnoid Hemorrhage
RGD
PMID:26100626 PMID:27000704 PMID:33414375
RGD:155791672 RGD:155804286 RGD:155882440
NCBI chrNW_004955411:17,177,335...17,229,957
Ensembl chrNW_004955411:17,177,335...17,229,957
G
Mbl2
mannose binding lectin 2
disease_progression
ISO
RGD
PMID:18183030
RGD:12910935
NCBI chrNW_004955425:7,704,371...7,708,951
Ensembl chrNW_004955425:7,702,137...7,709,006
G
Mbp
myelin basic protein
ISO
RGD
PMID:18583256
RGD:7349333
NCBI chrNW_004955402:60,324,060...60,448,926
Ensembl chrNW_004955402:60,323,950...60,441,406
G
Mdm2
MDM2 proto-oncogene
ISO
protein:increased expression:brain cortex (rat)
RGD
PMID:15165363
RGD:2317397
NCBI chrNW_004955458:15,264,028...15,287,290
Ensembl chrNW_004955458:15,263,739...15,286,808
G
Mif
macrophage migration inhibitory factor
ISO
RGD
PMID:15922484
RGD:1641989
NCBI chrNW_004955455:8,367,566...8,368,460
Ensembl chrNW_004955455:8,367,566...8,368,460
G
Mmp9
matrix metallopeptidase 9
treatment
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:16671440 PMID:19631748 PMID:24661104
RGD:13207312 RGD:1582656
NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288
G
Mpo
myeloperoxidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955451:4,743,744...4,753,358
Ensembl chrNW_004955451:4,743,744...4,753,358
G
Myoc
myocilin
ISO
mRNA:increased expression:cerebral cortex (rat)
RGD
PMID:12799138
RGD:7401267
NCBI chrNW_004955406:12,182,115...12,194,683
Ensembl chrNW_004955406:12,182,046...12,199,669
G
Nfe2l2
NFE2 like bZIP transcription factor 2
ISO
protein:increased expression:lung:
RGD
PMID:18787991 PMID:25089700
RGD:11576302 RGD:5134971
NCBI chrNW_004955403:19,510,122...19,536,428
Ensembl chrNW_004955403:19,532,103...19,535,944
G
Ngb
neuroglobin
severity
ISO
RGD
PMID:21915648
RGD:9743963
NCBI chrNW_004955438:1,170,888...1,175,978
Ensembl chrNW_004955438:1,170,888...1,175,978
G
Ngfr
nerve growth factor receptor
treatment
ISO
RGD
PMID:23940017
RGD:10414074
NCBI chrNW_004955451:12,030,303...12,047,305
Ensembl chrNW_004955451:12,030,252...12,047,305
G
Nos2
nitric oxide synthase 2
ISO
RGD
PMID:11526986
RGD:10395358
NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961
G
Nox4
NADPH oxidase 4
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:36762617
NCBI chrNW_004955414:4,062,337...4,220,032
Ensembl chrNW_004955414:4,062,081...4,212,746
G
Nppb
natriuretic peptide B
ISO
associated with lung diseases;protein:increased expression:serum: CTD Direct Evidence: therapeutic
RGD CTD
PMID:19803787 PMID:23837838
RGD:7247620
NCBI chrNW_004955486:2,054,775...2,056,130
G
Npy
neuropeptide Y
ISO
protein:increased expression:adrenal medulla
RGD
PMID:23570732
RGD:10448961
NCBI chrNW_004955410:26,348,388...26,355,232
Ensembl chrNW_004955410:26,348,504...26,355,297
G
Nqo1
NAD(P)H quinone dehydrogenase 1
treatment
ISO
mRNA:increased expression:lung associated with Subarachnoid Hemorrhage
RGD
PMID:18787991 PMID:20864352
RGD:11035222 RGD:5134971
NCBI chrNW_004955484:7,012,373...7,028,182
Ensembl chrNW_004955484:7,012,506...7,027,604
G
Nt5e
5'-nucleotidase ecto
ISO
protein:altered expression:cerebral cortex (rat)
RGD
PMID:21337375
RGD:5134348
NCBI chrNW_004955411:12,891,236...12,946,324
Ensembl chrNW_004955411:12,891,236...12,948,406
G
P2ry1
purinergic receptor P2Y1
ISO
protein:increased expression:brain, astrocyte
RGD
PMID:19115395
RGD:2315811
NCBI chrNW_004955448:4,366,706...4,372,626
Ensembl chrNW_004955448:4,366,706...4,372,626
G
Parp1
poly(ADP-ribose) polymerase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17640816
NCBI chrNW_004955489:520,875...557,609
Ensembl chrNW_004955489:520,875...557,615
G
Pawr
pro-apoptotic WT1 regulator
ISO
mRNA,protein:increased expression:brain:
RGD
PMID:11421591
RGD:9835358
NCBI chrNW_004955405:18,434,711...18,540,710
Ensembl chrNW_004955405:18,434,711...18,540,710
G
Pde4d
phosphodiesterase 4D
ISO
mRNA, protein:alternative form, decreased phosphorylation:brain
RGD
PMID:23057870
RGD:7327147
NCBI chrNW_004955446:7,914,326...9,252,527
Ensembl chrNW_004955446:8,211,877...9,252,653
G
Pdgfa
platelet derived growth factor subunit A
ISO
mRNA:increased expression:cerebral cortex, hippocampus
RGD
PMID:9645955
RGD:11084932
NCBI chrNW_004955460:8,328,400...8,346,755
Ensembl chrNW_004955460:8,326,891...8,346,550
G
Pdgfb
platelet derived growth factor subunit B
ISO
mRNA:increased expression:cerebral cortex, hippocampus
RGD
PMID:9645955
RGD:11084932
NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987
G
Pdgfra
platelet derived growth factor receptor alpha
ISO
mRNA:increased expression:cerebral cortex, hippocampus
RGD
PMID:9645955
RGD:11084932
NCBI chrNW_004955447:16,570,652...16,613,410
Ensembl chrNW_004955447:16,569,909...16,612,373
G
Pdgfrb
platelet derived growth factor receptor beta
ISO
mRNA:increased expression:cerebral cortex, hippocampus
RGD
PMID:9645955
RGD:11084932
NCBI chrNW_004955415:4,365,848...4,403,317
Ensembl chrNW_004955415:4,365,743...4,403,587
G
Pecam1
platelet and endothelial cell adhesion molecule 1
ISO
RGD
PMID:22658532
RGD:6484732
NCBI chrNW_004955478:7,448,584...7,531,860
Ensembl chrNW_004955478:7,478,492...7,531,188
G
Pglyrp1
peptidoglycan recognition protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004955574:424,046...427,675
Ensembl chrNW_004955574:424,142...427,540
G
Pgr
progesterone receptor
ISO
RGD
PMID:23211561
RGD:7248711
NCBI chrNW_004955412:4,643,839...4,693,478
G
Phb1
prohibitin 1
ISO
protein:increased oxidation:cerebral cortex
RGD
PMID:17518533
RGD:2292409
NCBI chrNW_004955451:12,110,290...12,119,870
Ensembl chrNW_004955451:12,110,290...12,120,124
G
Phb2
prohibitin 2
ISO
RGD
PMID:24566151
RGD:12903261
NCBI chrNW_004955413:4,557,969...4,563,697
Ensembl chrNW_004955413:4,558,259...4,563,582
G
Pias1
protein inhibitor of activated STAT 1
ISO
protein:decreased expression:brain, nucleus
RGD
PMID:21545521
RGD:8693413
NCBI chrNW_004955450:7,896,741...7,991,045
Ensembl chrNW_004955450:7,896,741...7,991,027
G
Ppara
peroxisome proliferator activated receptor alpha
ISO
agonist more effective in combination with simvastatin
RGD
PMID:18562561
RGD:5508455
NCBI chrNW_004955413:30,306,563...30,366,245
Ensembl chrNW_004955413:30,307,219...30,359,500
G
Ppargc1a
PPARG coactivator 1 alpha
treatment
ISO
protein:decreased expression:frontal cortex (rat)
RGD
PMID:22642418 PMID:24345766
RGD:10059630 RGD:6484257
NCBI chrNW_004955480:543,397...1,188,376
Ensembl chrNW_004955480:1,078,322...1,188,435
G
Ppp3ca
protein phosphatase 3 catalytic subunit alpha
ISO
protein: :hippocampus CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:14499481 PMID:19751097
RGD:6483311
NCBI chrNW_004955496:6,934,542...7,059,745
Ensembl chrNW_004955496:6,908,224...7,059,816
G
Prf1
perforin 1
ISO
RGD
PMID:20537642
RGD:6482807
NCBI chrNW_004955437:20,700,912...20,705,076
Ensembl chrNW_004955437:20,700,718...20,706,929
G
Ptger3
prostaglandin E receptor 3
ISO
protein:increased expression:striatum, microglia (rat)
RGD
PMID:15234107
RGD:9850280
NCBI chrNW_004955423:21,096,926...21,164,435
G
Ptgs1
prostaglandin-endoperoxide synthase 1
ISO
protein:increased expression:microglial cells, macrophage, endothelial cell protein:increased expression:microglia, macrophage
RGD
PMID:11565600 PMID:12005397 PMID:19719848
RGD:5688162 RGD:5688239 RGD:5688242
NCBI chrNW_004955419:5,678,750...5,699,305
Ensembl chrNW_004955419:5,678,694...5,699,305
G
Ptgs2
prostaglandin-endoperoxide synthase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:12410334 PMID:19719848 PMID:20810888 PMID:21549006 PMID:21866634
RGD:5508191 RGD:5688162
NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
G
Ptprz1
protein tyrosine phosphatase receptor type Z1
ISO
RGD
PMID:12088737
RGD:727637
NCBI chrNW_004955479:3,611,658...3,734,225
Ensembl chrNW_004955479:3,624,993...3,733,183
G
Rchy1
ring finger and CHY zinc finger domain containing 1
ISO
protein:increased expression:cerebral cortex
RGD
PMID:21728064
RGD:10045359
NCBI chrNW_004955474:1,463,817...1,475,677
Ensembl chrNW_004955474:1,463,817...1,475,690
G
Rela
RELA proto-oncogene, NF-kB subunit
ISO
protein:increased expression:ileum
RGD
PMID:18288455
RGD:2298787
NCBI chrNW_004955422:19,602,930...19,612,263
Ensembl chrNW_004955422:19,603,345...19,611,516
G
Ret
ret proto-oncogene
ISO
mRNA:increased expression:brain
RGD
PMID:18501516
RGD:2324932
NCBI chrNW_004955546:1,221,995...1,252,147
Ensembl chrNW_004955546:1,221,995...1,253,946
G
Rhoa
ras homolog family member A
ISO
protein:increased expression:microglial cell, brain
RGD
PMID:17929039
RGD:2298888
NCBI chrNW_004955532:1,300,821...1,347,453
Ensembl chrNW_004955532:1,300,462...1,347,451
G
Robo1
roundabout guidance receptor 1
ISO
mRNA:increased expression:brain protein:increased expression:brain, immune cell
RGD
PMID:16262652 PMID:26550694
RGD:2316136 RGD:243048437
NCBI chrNW_004955407:12,593,911...13,485,723
Ensembl chrNW_004955407:13,107,235...13,487,053
G
Robo2
roundabout guidance receptor 2
ISO
mRNA:increased expression:brain
RGD
PMID:16262652
RGD:2316136
NCBI chrNW_004955407:14,301,689...15,549,561
Ensembl chrNW_004955407:14,305,498...14,842,790
G
Robo3
roundabout guidance receptor 3
ISO
mRNA:increased expression:brain
RGD
PMID:16262652
RGD:2316136
NCBI chrNW_004955412:25,937,624...25,953,458
Ensembl chrNW_004955412:25,937,624...25,953,189
G
Rps27a
ribosomal protein S27a
ISO
mRNA:decreased expression:cerebral cortex, hippocampus
RGD
PMID:17936732
RGD:11041870
NCBI chrNW_004955424:27,823,575...27,825,489
Ensembl chrNW_004955424:27,823,575...27,825,489
G
S100b
S100 calcium binding protein B
severity
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
RGD CTD
PMID:11520488 PMID:21783483 PMID:21976236
RGD:5508761
NCBI chrNW_004955407:42,972,584...42,980,510
Ensembl chrNW_004955407:42,972,584...42,980,510
G
Sele
selectin E
ISO
protein:increased expression:brain
RGD
PMID:19107536
RGD:2313599
NCBI chrNW_004955462:7,564,437...7,575,297
G
Serpinc1
serpin family C member 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:21534203
NCBI chrNW_004955406:14,024,183...14,036,206
Ensembl chrNW_004955406:14,024,313...14,035,948
G
Serpinf1
serpin family F member 1
treatment
ISO
human gene in a rat model protein:altered expression:cerebellum (rat)
RGD
PMID:17709187 PMID:20142768
RGD:8612994 RGD:8622925
NCBI chrNW_004955481:1,414,930...1,426,436
Ensembl chrNW_004955481:1,414,930...1,426,241
G
Sirt1
sirtuin 1
treatment
ISO
RGD
PMID:17970622
RGD:9497541
NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663
G
Skp2
S-phase kinase associated protein 2
ISO
protein:increased expression:brain
RGD
PMID:19852587
RGD:2315049
NCBI chrNW_004955426:20,972,663...20,999,769
Ensembl chrNW_004955426:20,972,663...20,999,769
G
Slc18a3
solute carrier family 18 member A3
ISO
protein:decreased expression:brain
RGD
PMID:18848922
RGD:5686682
NCBI chrNW_004955556:696,779...698,869
Ensembl chrNW_004955556:696,974...698,566
G
Slit1
slit guidance ligand 1
ISO
mRNA:increased expression:brain
RGD
PMID:16262652
RGD:2316136
NCBI chrNW_004955507:3,204,135...3,365,319
Ensembl chrNW_004955507:3,201,556...3,365,471
G
Slit2
slit guidance ligand 2
exacerbates
ISO
RGD
PMID:26550694
RGD:243048437
NCBI chrNW_004955480:3,982,977...4,314,160
Ensembl chrNW_004955480:3,984,586...4,313,908
G
Slit3
slit guidance ligand 3
ISO
mRNA:increased expression:brain
RGD
PMID:16262652
RGD:2316136
NCBI chrNW_004955408:21,719,487...22,322,958
Ensembl chrNW_004955408:21,722,632...22,322,917
G
Snca
synuclein alpha
ISO
RGD
PMID:14637093 PMID:25089700
RGD:11576302 RGD:6480195
NCBI chrNW_004955405:854,011...962,741
Ensembl chrNW_004955405:853,946...965,403
G
Sncb
synuclein beta
ISO
RGD
PMID:14637093
RGD:6480195
NCBI chrNW_004955408:28,894,204...28,903,095
Ensembl chrNW_004955408:28,894,204...28,903,095
G
Sncg
synuclein gamma
ISO
RGD
PMID:14637093
RGD:6480195
NCBI chrNW_004955510:5,958,276...5,961,719
Ensembl chrNW_004955510:5,958,276...5,961,719
G
Snw1
SNW domain containing 1
ISO
mRNA, protein:increased expression:cerebral cortex (rat)
RGD
PMID:22965216
RGD:11035237
NCBI chrNW_004955438:1,561,562...1,601,492
Ensembl chrNW_004955438:1,561,568...1,601,492
G
Sod1
superoxide dismutase 1
ISO
RGD
PMID:16248885
RGD:1581214
NCBI chrNW_004955407:31,261,451...31,267,657
Ensembl chrNW_004955407:31,263,863...31,267,727
G
Sod2
superoxide dismutase 2
ISO
CTD Direct Evidence: therapeutic
CTD RGD
PMID:16248885 PMID:24462953
RGD:1581214
NCBI chrNW_004955439:21,209,101...21,223,538
Ensembl chrNW_004955439:21,209,101...21,224,163
G
Sparc
secreted protein acidic and cysteine rich
ISO
mRNA:increased expression:brain, blood vessel
RGD
PMID:9704602
RGD:2300066
NCBI chrNW_004955408:6,100,123...6,122,460
Ensembl chrNW_004955408:6,099,003...6,122,459
G
Sstr2
somatostatin receptor 2
ISO
RGD
PMID:11879809
RGD:2325002
NCBI chrNW_004955478:61,126...123,806
Ensembl chrNW_004955478:60,489...90,209
G
Sstr3
somatostatin receptor 3
ISO
RGD
PMID:11879809
RGD:2325002
NCBI chrNW_004955413:23,677,693...23,683,939
Ensembl chrNW_004955413:23,677,693...23,683,939
G
Stat1
signal transducer and activator of transcription 1
ISO
RGD
PMID:21596098
RGD:6483023
NCBI chrNW_004955403:8,156,660...8,192,018
Ensembl chrNW_004955403:8,156,660...8,194,762
G
Stat3
signal transducer and activator of transcription 3
ISO
protein:increased phosphorylation:brain
RGD
PMID:21596098 PMID:22145815 PMID:22827467
RGD:6483023 RGD:6892706 RGD:8694312
NCBI chrNW_004955451:16,320,326...16,348,505
Ensembl chrNW_004955451:16,319,904...16,357,687
G
Strn
striatin
ISO
RGD
PMID:16351572
RGD:2311293
NCBI chrNW_004955441:4,682,200...4,781,236
Ensembl chrNW_004955441:4,682,200...4,781,275
G
Tardbp
TAR DNA binding protein
ISO
RGD
PMID:22101322
RGD:5687195
NCBI chrNW_004955486:2,656,121...2,674,808
Ensembl chrNW_004955486:2,656,121...2,674,807
G
Th
tyrosine hydroxylase
ISO
protein:decreased activity:striatum (rat)
RGD
PMID:21047500
RGD:5128822
NCBI chrNW_004955422:13,943,590...13,951,102
Ensembl chrNW_004955422:13,943,552...13,951,137
G
Thbd
thrombomodulin
onset
ISO
RGD
PMID:17895610
RGD:5685007
NCBI chrNW_004955415:30,222,830...30,226,406
G
Ticam2
toll like receptor adaptor molecule 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004955411:31,010,373...31,042,321
G
Timp1
TIMP metallopeptidase inhibitor 1
ISO
mRNA:increased expression:brain, astrocytes
RGD
PMID:10719361
RGD:2290468
NCBI chrNW_004955516:507,113...511,360
Ensembl chrNW_004955516:505,789...512,118
G
Timp2
TIMP metallopeptidase inhibitor 2
ISO
mRNA:increased expression:brain, neuron, microglial cell
RGD
PMID:10719361
RGD:2290468
NCBI chrNW_004955506:3,769,113...3,812,896
Ensembl chrNW_004955506:3,768,646...3,813,820
G
Tjp1
tight junction protein 1
ISO
RGD
PMID:19889224
RGD:2325128
NCBI chrNW_004955416:28,640,807...28,869,717
Ensembl chrNW_004955416:28,654,905...28,870,555
G
Tlr1
toll like receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004955443:8,442,419...8,450,318
Ensembl chrNW_004955443:8,447,956...8,450,382
G
Tlr2
toll like receptor 2
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:brain
CTD RGD
PMID:18316784 PMID:21549006
RGD:2312713
NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
G
Tlr4
toll like receptor 4
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:brain
CTD RGD
PMID:18316784 PMID:21549006
RGD:2312713
NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
G
Tlr9
toll like receptor 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21549006
NCBI chrNW_004955532:3,828,645...3,832,699
Ensembl chrNW_004955532:3,828,775...3,832,582
G
Tnf
tumor necrosis factor
ISO
CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:10674461 PMID:19800810 PMID:21549006
RGD:13825262
NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
G
Tnfrsf13b
TNF receptor superfamily member 13B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955577:930,612...971,698
G
Tnfrsf13c
TNF receptor superfamily member 13C
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955413:27,341,977...27,344,009
G
Tnfrsf14
TNF receptor superfamily member 14
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955486:8,670,182...8,684,677
G
Tnfrsf1a
TNF receptor superfamily member 1A
ISO
protein:increased expression:brain CTD Direct Evidence: marker/mechanism
RGD CTD
PMID:17074049 PMID:21549006
RGD:1624183
NCBI chrNW_004955413:3,982,670...3,996,320
Ensembl chrNW_004955413:3,981,400...3,996,021
G
Tnfsf10
TNF superfamily member 10
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955420:2,550,392...2,566,448
Ensembl chrNW_004955420:2,549,142...2,566,564
G
Traf4
TNF receptor associated factor 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23159883
NCBI chrNW_004955481:4,410,906...4,417,553
Ensembl chrNW_004955481:4,410,906...4,417,061
G
Trpm2
transient receptor potential cation channel subfamily M member 2
ISO
mRNA, protein:increased expression:cerebral cortex, hippocampus
RGD
PMID:20309649
RGD:9999437
NCBI chrNW_004955407:41,062,217...41,110,500
Ensembl chrNW_004955407:41,057,941...41,110,668
G
Uba52
ubiquitin A-52 residue ribosomal protein fusion product 1
ISO
mRNA:decreased expression:cerebral cortex, hippocampus (rat)
RGD
PMID:17936732
RGD:11041870
NCBI chrNW_004955524:3,007,074...3,009,886
Ensembl chrNW_004955524:3,006,147...3,018,772
G
Ucp2
uncoupling protein 2
ISO
CTD Direct Evidence: therapeutic
RGD CTD
PMID:12858170
RGD:7204436
NCBI chrNW_004955414:17,592,914...17,596,477
Ensembl chrNW_004955414:17,592,914...17,596,477
G
Vegfa
vascular endothelial growth factor A
ISO
CTD Direct Evidence: therapeutic
CTD RGD
PMID:12230324 PMID:18065154
RGD:1580574
NCBI chrNW_004955437:9,527,445...9,541,908
G
Vegfb
vascular endothelial growth factor B
ISO
mRNA, protein:increased expression:brain
RGD
PMID:12230324
RGD:1580574
NCBI chrNW_004955422:20,840,055...20,843,182
Ensembl chrNW_004955422:20,840,055...20,843,225
G
Vim
vimentin
ISO
protein:increased expression:brain
RGD
PMID:15527750 PMID:19728994
RGD:6480519 RGD:6480527
NCBI chrNW_004955429:10,708,852...10,716,743
Ensembl chrNW_004955429:10,707,719...10,717,554
G
Apoe
apolipoprotein E
susceptibility
ISO
DNA:polymorphism:exon:
RGD
PMID:9214529
RGD:7495763
NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
G
Tardbp
TAR DNA binding protein
ISO
protein:increased expression:brain
RGD
PMID:20720505
RGD:5687179
NCBI chrNW_004955486:2,656,121...2,674,808
Ensembl chrNW_004955486:2,656,121...2,674,807
G
Becn1
beclin 1
ISO
protein:increased expression:neuron
RGD
PMID:16004578
RGD:6483315
NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730
G
Gfap
glial fibrillary acidic protein
ISO
RGD
PMID:8833197
RGD:6480531
NCBI chrNW_004955451:17,695,835...17,703,894
Ensembl chrNW_004955451:17,695,835...17,703,268
G
Got1
glutamic-oxaloacetic transaminase 1
ISO
human protein in a rat model
RGD
PMID:17014847
RGD:13504858
NCBI chrNW_004955507:5,346,937...5,370,072
Ensembl chrNW_004955507:5,346,838...5,370,072
G
Igf1
insulin like growth factor 1
ISO
protein:decreased expression:serum:
RGD
PMID:12002507
RGD:8548865
NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
G
Igfbp3
insulin like growth factor binding protein 3
ISO
protein:decreased expression:serum:
RGD
PMID:12002507
RGD:8548865
NCBI chrNW_004955456:6,795,560...6,802,147
Ensembl chrNW_004955456:6,795,604...6,800,845
G
Vim
vimentin
ISO
RGD
PMID:8833197
RGD:6480531
NCBI chrNW_004955429:10,708,852...10,716,743
Ensembl chrNW_004955429:10,707,719...10,717,554
G
Aldh3a1
aldehyde dehydrogenase 3 family member A1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28038895
NCBI chrNW_004955467:96,140...105,738
Ensembl chrNW_004955467:96,140...105,738
G
Tp63
tumor protein p63
ISO
RGD
PMID:12167247
RGD:11568649
NCBI chrNW_004955420:18,178,639...18,384,786
Ensembl chrNW_004955420:18,176,155...18,384,786
G
Ifng
interferon gamma
ISO
mRNA,protein:increased expression:corneal
RGD
PMID:15832292
RGD:8157597
NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045
G
Bmp4
bone morphogenetic protein 4
ISO
mRNA:increased expression:superior cervical ganglion
RGD
PMID:16420416
RGD:2289006
NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303
G
Cx3cl1
C-X3-C motif chemokine ligand 1
ISO
RGD
PMID:15153618
RGD:4891994
NCBI chrNW_004955433:15,023,272...15,034,650
Ensembl chrNW_004955433:15,023,050...15,034,711
G
S100b
S100 calcium binding protein B
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30076900
NCBI chrNW_004955407:42,972,584...42,980,510
Ensembl chrNW_004955407:42,972,584...42,980,510
G
Il10
interleukin 10
treatment
ISO
RGD
PMID:22553604
RGD:7364851
NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
G
Il1b
interleukin 1 beta
ISO
protein:increased expression:retina
RGD
PMID:9618720
RGD:7794723
NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
G
Pparg
peroxisome proliferator activated receptor gamma
ISO
protein:increased expression:cornea, neutrophil, macrophage (rat)
RGD
PMID:24194635
RGD:8552904
NCBI chrNW_004955429:14,814,690...14,936,869
Ensembl chrNW_004955429:14,873,908...14,937,387
G
Fgf2
fibroblast growth factor 2
ISO
protein:increased expression:lens
RGD
PMID:15273655
RGD:8655664
NCBI chrNW_004955428:17,840,554...17,894,779
Ensembl chrNW_004955428:17,840,628...17,894,773
G
Pparg
peroxisome proliferator activated receptor gamma
treatment
ISO
RGD
PMID:18658087
RGD:8552893
NCBI chrNW_004955429:14,814,690...14,936,869
Ensembl chrNW_004955429:14,873,908...14,937,387
G
Adcyap1
adenylate cyclase activating polypeptide 1
ISO
mRNA:increased expression:facial VII nucleus
RGD
PMID:19427307
RGD:2325258
NCBI chrNW_004955402:9,091,927...9,099,803
Ensembl chrNW_004955402:9,091,725...9,099,803
G
Atf2
activating transcription factor 2
ISO
RGD
PMID:9813301
RGD:10047413
NCBI chrNW_004955449:332,563...411,218
Ensembl chrNW_004955449:338,193...411,218
G
Ccr3
C-C motif chemokine receptor 3
ISO
RGD
PMID:19922414
RGD:6892922
NCBI chrNW_004955420:25,702,917...25,723,269
Ensembl chrNW_004955420:25,701,407...25,723,353
G
Cd59
CD59 molecule (CD59 blood group)
ISO
mRNA, protein:increased expression:facial VII nucleus
RGD
PMID:9846834
RGD:1600495
NCBI chrNW_004955422:12,500,572...12,528,738
G
Clu
clusterin
ISO
protein:increased expression:neuron,astrocyte
RGD
PMID:10800205
RGD:408418725
NCBI chrNW_004955403:50,160,598...50,175,876
Ensembl chrNW_004955403:50,160,598...50,175,876
G
Csf1
colony stimulating factor 1
ISO
protein:increased expression:facial VII nerve, microglial cell
RGD
PMID:20831658
RGD:5131509
NCBI chrNW_004955435:13,404,236...13,423,059
Ensembl chrNW_004955435:13,404,508...13,424,247
G
Ctss
cathepsin S
ISO
RGD
PMID:17539023
RGD:5686912
NCBI chrNW_004955413:99,279...124,793
Ensembl chrNW_004955413:99,159...124,042
G
Gfra1
GDNF family receptor alpha 1
ISO
mRNA:increased expression:facial VII nucleus
RGD
PMID:9582449
RGD:6218984
NCBI chrNW_004955431:20,859,152...21,070,886
Ensembl chrNW_004955431:20,866,685...21,070,853
G
Hgf
hepatocyte growth factor
treatment
ISO
RGD
PMID:21562589
RGD:8548634
NCBI chrNW_004955410:4,114,280...4,181,953
Ensembl chrNW_004955410:4,114,778...4,182,058
G
Ndufa5
NADH:ubiquinone oxidoreductase subunit A5
ISO
mRNA:increased expression:skeletal muscle
RGD
PMID:8875451
RGD:2302319
NCBI chrNW_004955479:5,065,948...5,080,215
Ensembl chrNW_004955479:5,064,652...5,080,215
G
Ret
ret proto-oncogene
ISO
mRNA:increased expression:facial VII nucleus
RGD
PMID:9582449
RGD:6218984
NCBI chrNW_004955546:1,221,995...1,252,147
Ensembl chrNW_004955546:1,221,995...1,253,946
G
Acvr1b
activin A receptor type 1B
ISO
RGD
PMID:9013782
RGD:151665480
NCBI chrNW_004955547:2,311,573...2,366,106
Ensembl chrNW_004955547:2,323,771...2,367,263
G
Adamts1
ADAM metallopeptidase with thrombospondin type 1 motif 1
ISO
mRNA:increased expression:hypoglossal nerve
RGD
PMID:11311987
RGD:5037239
NCBI chrNW_004955407:26,524,487...26,533,038
Ensembl chrNW_004955407:26,524,130...26,533,038
G
Aif1
allograft inflammatory factor 1
ISO
RGD
PMID:9698327
RGD:704401
NCBI chrNW_004955437:157,509...158,919
Ensembl chrNW_004955437:157,509...158,919
G
Csnk2b
casein kinase 2 beta
ISO
RGD
PMID:11068334
RGD:11565824
NCBI chrNW_004955437:210,541...215,725
Ensembl chrNW_004955437:210,838...219,694
G
Fgf2
fibroblast growth factor 2
ISO
RGD
PMID:9183688
RGD:8655640
NCBI chrNW_004955428:17,840,554...17,894,779
Ensembl chrNW_004955428:17,840,628...17,894,773
G
Fgfr1
fibroblast growth factor receptor 1
ISO
RGD
PMID:9183688
RGD:8655640
NCBI chrNW_004955463:14,013,247...14,064,354
Ensembl chrNW_004955463:14,013,247...14,064,111
G
Gfra1
GDNF family receptor alpha 1
ISO
mRNA:increased expression:hypoglossal XII nerve
RGD
PMID:10407179
RGD:6218979
NCBI chrNW_004955431:20,859,152...21,070,886
Ensembl chrNW_004955431:20,866,685...21,070,853
G
Il1r1
interleukin 1 receptor type 1
ISO
mRNA:increased expression:hypoglossal nerve
RGD
PMID:11311987
RGD:5037239
NCBI chrNW_004955470:7,685,498...7,703,374
G
Mcam
melanoma cell adhesion molecule
ISO
RGD
PMID:10076889
RGD:7364787
NCBI chrNW_004955412:20,396,056...20,404,777
Ensembl chrNW_004955412:20,397,051...20,404,780
G
Mme
membrane metalloendopeptidase
ISO
RGD
PMID:8201016
RGD:13801045
NCBI chrNW_004955448:6,193,113...6,311,666
Ensembl chrNW_004955448:6,226,059...6,314,949
G
Prkaca
protein kinase cAMP-activated catalytic subunit alpha
ISO
RGD
PMID:7769990
RGD:7327191
NCBI chrNW_004955415:32,794,172...32,807,944
Ensembl chrNW_004955415:32,793,718...32,812,930
G
Prkacb
protein kinase cAMP-activated catalytic subunit beta
ISO
RGD
PMID:7769990
RGD:7327191
NCBI chrNW_004955423:9,630,308...9,747,820
Ensembl chrNW_004955423:9,629,378...9,747,820
G
Ret
ret proto-oncogene
ISO
mRNA:increased expression:hypoglossal XII nerve
RGD
PMID:10407179
RGD:6218979
NCBI chrNW_004955546:1,221,995...1,252,147
Ensembl chrNW_004955546:1,221,995...1,253,946
G
Smad1
SMAD family member 1
ISO
mRNA:increased expression:hypoglossal nucleus
RGD
PMID:17166487
RGD:1643227
NCBI chrNW_004955428:1,357,398...1,429,521
Ensembl chrNW_004955428:1,361,085...1,429,948
G
Smad2
SMAD family member 2
ISO
mRNA:increased expression:hypoglossal nucleus
RGD
PMID:17166487
RGD:1643227
NCBI chrNW_004955402:33,131,760...33,217,144
Ensembl chrNW_004955402:33,136,778...33,216,844
G
Smad3
SMAD family member 3
ISO
mRNA:increased expression:hypoglossal nucleus
RGD
PMID:17166487
RGD:1643227
NCBI chrNW_004955450:8,747,651...8,842,003
Ensembl chrNW_004955450:8,747,651...8,842,136
G
Smad4
SMAD family member 4
ISO
mRNA:increased expression:hypoglossal nucleus
RGD
PMID:17166487
RGD:1643227
NCBI chrNW_004955402:35,956,080...36,001,746
Ensembl chrNW_004955402:35,961,165...35,994,538
G
Smad7
SMAD family member 7
ISO
mRNA:increased expression:hypoglossal nucleus
RGD
PMID:17166487
RGD:1643227
NCBI chrNW_004955402:34,028,184...34,058,949
Ensembl chrNW_004955402:34,028,063...34,058,291
G
Smad9
SMAD family member 9
ISO
mRNA:decreased expression:hypoglossal nucleus
RGD
PMID:17166487
RGD:1643227
NCBI chrNW_004955431:9,117,616...9,184,920
G
Txnrd1
thioredoxin reductase 1
ISO
mRNA, protein:increased expression:neuron
RGD
PMID:19833109
RGD:5133729
NCBI chrNW_004955405:38,863,762...38,928,615
Ensembl chrNW_004955405:38,903,918...38,927,410
G
Mdm2
MDM2 proto-oncogene
treatment
ISO
RGD
PMID:34334113
RGD:155882538
NCBI chrNW_004955458:15,264,028...15,287,290
Ensembl chrNW_004955458:15,263,739...15,286,808
G
Zeb2
zinc finger E-box binding homeobox 2
treatment
ISO
protein:increased expression:brain (rat)
RGD
PMID:34334113
RGD:155882538
NCBI chrNW_004955440:10,755,658...10,881,044
Ensembl chrNW_004955440:10,756,014...10,795,491
G
Cited2
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2
ISO
mRNA:decreased expression:bone
RGD
PMID:19607804
RGD:5147852
NCBI chrNW_004955436:20,370,950...20,372,677
Ensembl chrNW_004955436:20,370,950...20,372,677
G
Ihh
Indian hedgehog signaling molecule
ISO
RGD
PMID:23992905
RGD:12911207
NCBI chrNW_004955453:14,376,665...14,382,536
Ensembl chrNW_004955453:14,376,718...14,381,747
G
Ntrk2
neurotrophic receptor tyrosine kinase 2
ISO
mRNA:increased expression:motor neuron
RGD
PMID:21456016
RGD:5684341
NCBI chrNW_004955432:2,284,283...2,629,631
Ensembl chrNW_004955432:2,288,898...2,630,878
G
Adcy10
adenylate cyclase 10
ISO
protein:decreased expression:retina
RGD
PMID:22649251
RGD:329347828
NCBI chrNW_004955462:9,196,984...9,278,850
Ensembl chrNW_004955462:9,207,314...9,278,621
G
Adnp
activity dependent neuroprotector homeobox
ISO
RGD
PMID:18414890
RGD:2312783
NCBI chrNW_004955445:7,498,223...7,530,828
Ensembl chrNW_004955445:7,492,257...7,531,862
G
Amigo3
adhesion molecule with Ig like domain 3
treatment
ISO
RGD
PMID:23613963
RGD:14390159
NCBI chrNW_004955532:1,618,659...1,621,706
Ensembl chrNW_004955532:1,619,532...1,621,064
G
Aqp4
aquaporin 4
ISO
RGD
PMID:20216911
RGD:2326035
NCBI chrNW_004955772:1,160...10,709
Ensembl chrNW_004955772:1,159...10,709
G
Aqp9
aquaporin 9
ISO
RGD
PMID:20216911
RGD:2326035
NCBI chrNW_004955450:16,253,706...16,346,602
Ensembl chrNW_004955450:16,253,571...16,302,657
G
Arg2
arginase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30618589
NCBI chrNW_004955466:2,549,557...2,577,060
Ensembl chrNW_004955466:2,549,557...2,577,060
G
Atf2
activating transcription factor 2
ISO
RGD
PMID:10366744
RGD:10047417
NCBI chrNW_004955449:332,563...411,218
Ensembl chrNW_004955449:338,193...411,218
G
Bax
BCL2 associated X, apoptosis regulator
ISO
mRNA:increased expression:optic nerve, retina
RGD
PMID:24357921
RGD:10054098
NCBI chrNW_004955559:1,695,960...1,700,246
Ensembl chrNW_004955559:1,695,960...1,700,244
G
Bcl2
BCL2 apoptosis regulator
ISO
mRNA:decreased expression:optic nerve, retina
RGD
PMID:24357921
RGD:10054098
NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485
G
Bdnf
brain derived neurotrophic factor
treatment
ISO
RGD
PMID:9520478 PMID:11050383 PMID:15140649
RGD:8655584 RGD:8655586 RGD:8655637
NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
G
C3
complement C3
ISO
mRNA:increased expression:optic nerve
RGD
PMID:14577867
RGD:5129542
NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697
G
Cdk2
cyclin dependent kinase 2
ISO
mRNA:increased expression:retina
RGD
PMID:16723461
RGD:2293567
NCBI chrNW_004955458:3,555,603...3,561,063
Ensembl chrNW_004955458:3,555,603...3,562,120
G
Cfl1
cofilin 1
treatment
ISO
RGD
PMID:27443501
RGD:11568693
NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571
G
Clu
clusterin
ISO
RGD
PMID:14577867
RGD:5129542
NCBI chrNW_004955403:50,160,598...50,175,876
Ensembl chrNW_004955403:50,160,598...50,175,876
G
Csf1r
colony stimulating factor 1 receptor
ISO
mRNA:increased expression:retina (rat)
RGD
PMID:20187850
RGD:151665810
NCBI chrNW_004955415:4,434,486...4,462,505
Ensembl chrNW_004955415:4,434,453...4,461,751
G
Csf3
colony stimulating factor 3
treatment
ISO
RGD
PMID:20144610
RGD:11039471
NCBI chrNW_004955451:14,688,181...14,690,126
Ensembl chrNW_004955451:14,688,181...14,690,126
G
Ctsb
cathepsin B
ISO
protein:increased expression:retina (rat)
RGD
PMID:18775855
RGD:2315508
NCBI chrNW_004955403:53,086,236...53,100,217
Ensembl chrNW_004955403:53,085,574...53,093,809
G
Edn1
endothelin 1
ISO
protein:increased expression:retina
RGD
PMID:18600494
RGD:4892579
NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753
G
Ednra
endothelin receptor type A
ISO
mRNA:increased expression:retina
RGD
PMID:18600494
RGD:4892579
NCBI chrNW_004955428:3,062,303...3,114,761
Ensembl chrNW_004955428:3,062,303...3,114,761
G
Ednrb
endothelin receptor type B
ISO
mRNA:increased expression:retina
RGD
PMID:18600494
RGD:4892579
NCBI chrNW_004955404:29,394,253...29,425,358
Ensembl chrNW_004955404:29,394,164...29,425,358
G
Ep300
E1A binding protein p300
ISO
human gene in rat model protein:decreased expression:retinal ganglion cell layer (rat)
RGD
PMID:21705428
RGD:7349392
NCBI chrNW_004955413:26,647,553...26,727,875
Ensembl chrNW_004955413:26,648,339...26,727,933
G
Fgf2
fibroblast growth factor 2
treatment
ISO
RGD
PMID:14664816
RGD:8554854
NCBI chrNW_004955428:17,840,554...17,894,779
Ensembl chrNW_004955428:17,840,628...17,894,773
G
Fto
FTO alpha-ketoglutarate dependent dioxygenase
ISO
mRNA:increased expression:retina
RGD
PMID:33664770
RGD:329951020
NCBI chrNW_004955433:11,424,069...11,834,955
Ensembl chrNW_004955433:11,424,176...11,813,771
G
Gdnf
glial cell derived neurotrophic factor
ISO
RGD
PMID:15144875
RGD:6218970
NCBI chrNW_004955426:22,386,613...22,412,324
Ensembl chrNW_004955426:22,386,450...22,412,324
G
Gfra1
GDNF family receptor alpha 1
ISO
RGD
PMID:15144875
RGD:6218970
NCBI chrNW_004955431:20,859,152...21,070,886
Ensembl chrNW_004955431:20,866,685...21,070,853
G
Gfra2
GDNF family receptor alpha 2
ISO
RGD
PMID:15144875
RGD:6218970
NCBI chrNW_004955403:45,235,161...45,324,825
Ensembl chrNW_004955403:45,235,119...45,324,946
G
Hgf
hepatocyte growth factor
treatment
ISO
RGD
PMID:21443522
RGD:8548549
NCBI chrNW_004955410:4,114,280...4,181,953
Ensembl chrNW_004955410:4,114,778...4,182,058
G
Igf1r
insulin like growth factor 1 receptor
ISO
protein: altered activity: eye protein:increased expression:retina:
RGD
PMID:19484445 PMID:23648097
RGD:10046025 RGD:5686431
NCBI chrNW_004955416:26,101,090...26,382,660
Ensembl chrNW_004955416:26,102,628...26,382,666
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
ISO
RGD
PMID:10366744
RGD:10047417
NCBI chrNW_004955464:1,107,598...1,110,326
G
Kcnj10
potassium inwardly rectifying channel subfamily J member 10
ISO
RGD
PMID:20216911
RGD:2326035
NCBI chrNW_004955468:11,828,525...11,860,365
Ensembl chrNW_004955468:11,828,525...11,860,365
G
Myrf
myelin regulatory factor
ISO
mRNA:decreased expression: oligodendrocyte
RGD
PMID:29915135
RGD:213230153
NCBI chrNW_004955511:5,927,103...5,949,289
Ensembl chrNW_004955511:5,927,698...5,942,242
G
Nampt
nicotinamide phosphoribosyltransferase
treatment
ISO
RGD
PMID:28032230
RGD:13781885
NCBI chrNW_004955410:10,717,664...10,742,109
Ensembl chrNW_004955410:10,717,664...10,751,177
G
Ncam1
neural cell adhesion molecule 1
ISO
RGD
PMID:18757519
RGD:2326023
NCBI chrNW_004955412:14,630,109...14,923,847
Ensembl chrNW_004955412:14,630,443...14,923,926
G
Nefm
neurofilament medium chain
ISO
RGD
PMID:8501527
RGD:9743936
NCBI chrNW_004955403:47,920,408...47,926,922
G
Neo1
neogenin 1
ISO
protein:increased expression:retina
RGD
PMID:21887516
RGD:9850142
NCBI chrNW_004955450:4,191,168...4,324,997
Ensembl chrNW_004955450:4,191,168...4,375,896
G
Ngf
nerve growth factor
ISO
protein:increased expression:retina
RGD
PMID:28067793
RGD:402463954
NCBI chrNW_004955435:18,581,889...18,633,330
Ensembl chrNW_004955435:18,581,808...18,601,059
G
Ngfr
nerve growth factor receptor
ISO
RGD
PMID:20943663
RGD:5508695
NCBI chrNW_004955451:12,030,303...12,047,305
Ensembl chrNW_004955451:12,030,252...12,047,305
G
Ntrk1
neurotrophic receptor tyrosine kinase 1
ISO
RGD
PMID:20943663
RGD:5508695
NCBI chrNW_004955545:2,929,704...2,947,579
Ensembl chrNW_004955545:2,929,704...2,947,579
G
Ntrk2
neurotrophic receptor tyrosine kinase 2
treatment
ISO
RGD
PMID:20357199 PMID:34245756
RGD:5684908 RGD:597015764
NCBI chrNW_004955432:2,284,283...2,629,631
Ensembl chrNW_004955432:2,288,898...2,630,878
G
Pawr
pro-apoptotic WT1 regulator
ISO
mRNA:increased expression:retina:
RGD
PMID:12836167
RGD:1299297
NCBI chrNW_004955405:18,434,711...18,540,710
Ensembl chrNW_004955405:18,434,711...18,540,710
G
Pax6
paired box 6
ISO
protein:increased expression:retina (rat)
RGD
PMID:23297010
RGD:8552379
NCBI chrNW_004955476:10,058,979...10,074,668
Ensembl chrNW_004955476:10,058,961...10,074,162
G
Pdgfb
platelet derived growth factor subunit B
ISO
protein:decreased expression:nerve fiber:
RGD
PMID:9893812
RGD:10449496
NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987
G
Pecam1
platelet and endothelial cell adhesion molecule 1
ISO
protein:increased expression:optic nerve (rat)
RGD
PMID:22336118
RGD:6767293
NCBI chrNW_004955478:7,448,584...7,531,860
Ensembl chrNW_004955478:7,478,492...7,531,188
G
Plau
plasminogen activator, urokinase
ISO
mRNA:increased expression:optic nerve (rat)
RGD
PMID:20798533
RGD:6483802
NCBI chrNW_004955437:17,995,726...18,000,542
Ensembl chrNW_004955437:17,994,537...18,000,209
G
Ptpn5
protein tyrosine phosphatase non-receptor type 5
ISO
protein:increased expression:retina (rat)
RGD
PMID:15555919
RGD:9835027
NCBI chrNW_004955414:33,381,783...33,436,974
Ensembl chrNW_004955414:33,377,322...33,437,118
G
Rhoa
ras homolog family member A
ISO
protein:increased expression, altered localization:retina
RGD
PMID:17534117
RGD:1642826
NCBI chrNW_004955532:1,300,821...1,347,453
Ensembl chrNW_004955532:1,300,462...1,347,451
G
Snw1
SNW domain containing 1
ISO
protein:increased expression:retina (rat)
RGD
PMID:25074585
RGD:11035254
NCBI chrNW_004955438:1,561,562...1,601,492
Ensembl chrNW_004955438:1,561,568...1,601,492
G
Tlr2
toll like receptor 2
treatment
ISO
RGD
PMID:19661221
RGD:597538516
NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
G
Tlr4
toll like receptor 4
ISO
protein:increased expression:optic nerve
RGD
PMID:23103505
RGD:7794777
NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
G
Tnfrsf1a
TNF receptor superfamily member 1A
ISO
RGD
PMID:14697498 PMID:18552980
RGD:7794683 RGD:8661743
NCBI chrNW_004955413:3,982,670...3,996,320
Ensembl chrNW_004955413:3,981,400...3,996,021
G
Tradd
TNFRSF1A associated via death domain
ISO
protein:increased expression: retina
RGD
PMID:18552980
RGD:7794683
NCBI chrNW_004955484:9,456,268...9,462,425
Ensembl chrNW_004955484:9,456,301...9,462,425
G
Ybx3
Y-box binding protein 3
ISO
mRNA:increased expression:retinal ganglion cell
RGD
PMID:11750989
RGD:2311250
NCBI chrNW_004955413:7,090,085...7,111,542
Ensembl chrNW_004955413:7,089,719...7,108,473
G
Fgf2
fibroblast growth factor 2
ISO
mRNA:increased expression:retina
RGD
PMID:9268592
RGD:8655567
NCBI chrNW_004955428:17,840,554...17,894,779
Ensembl chrNW_004955428:17,840,628...17,894,773
G
Neo1
neogenin 1
ISO
protein:increased expression:retina
RGD
PMID:21887516
RGD:9850142
NCBI chrNW_004955450:4,191,168...4,324,997
Ensembl chrNW_004955450:4,191,168...4,375,896
G
Rgma
repulsive guidance molecule BMP co-receptor a
ISO
protein:increased expression:retina
RGD
PMID:21887516
RGD:9850142
NCBI chrNW_004955416:21,221,023...21,261,831
Ensembl chrNW_004955416:21,221,023...21,261,831
G
Entpd1
ectonucleoside triphosphate diphosphohydrolase 1
ISO
protein:increased expression,increased activity:cerebral cortex:
RGD
PMID:16672190
RGD:9685448
NCBI chrNW_004955507:2,035,918...2,141,327
Ensembl chrNW_004955507:2,036,050...2,137,377
G
Fgfr1
fibroblast growth factor receptor 1
ISO
mRNA,protein:increased expression:astrocyte,macrophage,neutrophil:
RGD
PMID:11168551
RGD:10402049
NCBI chrNW_004955463:14,013,247...14,064,354
Ensembl chrNW_004955463:14,013,247...14,064,111
G
Gfap
glial fibrillary acidic protein
ISO
RGD
PMID:10225952
RGD:6480471
NCBI chrNW_004955451:17,695,835...17,703,894
Ensembl chrNW_004955451:17,695,835...17,703,268
G
Pdgfb
platelet derived growth factor subunit B
ISO
protein:increased expression:neuron:
RGD
PMID:7526956
RGD:10449485
NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987
G
Vim
vimentin
ISO
RGD
PMID:10225952
RGD:6480471
NCBI chrNW_004955429:10,708,852...10,716,743
Ensembl chrNW_004955429:10,707,719...10,717,554
G
Trh
thyrotropin releasing hormone
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:8690305
NCBI chrNW_004955429:17,487,275...17,489,385
G
Bmp4
bone morphogenetic protein 4
treatment
ISO
RGD
PMID:16332232
RGD:8699514
NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303
G
Igf1
insulin like growth factor 1
ISO
protein:decreased expression:serum:
RGD
PMID:12002507
RGD:8548865
NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
G
Plat
plasminogen activator, tissue type
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:1899364
NCBI chrNW_004955536:730,962...754,333
Ensembl chrNW_004955536:730,981...756,394
G
Adam10
ADAM metallopeptidase domain 10
ISO
RGD
PMID:22489706
RGD:13703033
NCBI chrNW_004955450:15,853,372...15,927,966
Ensembl chrNW_004955450:15,853,366...15,928,200
G
Ahr
aryl hydrocarbon receptor
ISO
protein:increased expression:T cell, neuron, brain cortex, hippocampus
RGD
PMID:27506546
RGD:405878081
NCBI chrNW_004955410:20,428,531...20,459,482
Ensembl chrNW_004955410:20,428,546...20,456,836
G
App
amyloid beta precursor protein
treatment
ISO
RGD
PMID:29320530
RGD:13782048
NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268
G
Bad
BCL2 associated agonist of cell death
treatment
ISO
RGD
PMID:24582457
RGD:13782254
NCBI chrNW_004955422:20,795,585...20,809,039
Ensembl chrNW_004955422:20,795,676...20,809,245
G
Bdnf
brain derived neurotrophic factor
ISO
mRNA:increased expression:CA3 field of hippocampus, dentate gyrus
RGD
PMID:10925157
RGD:596936229
NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
G
Bid
BH3 interacting domain death agonist
severity disease_progression
ISO
RGD
PMID:12172380 PMID:15307896
RGD:5509821 RGD:632018
NCBI chrNW_004955454:5,776,656...5,785,500
Ensembl chrNW_004955454:5,777,667...5,783,118
G
Capn1
calpain 1
severity
ISO
protein:increased expression:cytosol, plasma membrane
RGD
PMID:9469158 PMID:15307896
RGD:13792664 RGD:5509821
NCBI chrNW_004955422:20,006,448...20,026,984
Ensembl chrNW_004955422:20,004,426...20,025,708
G
Capn2
calpain 2
severity
ISO
RGD
PMID:9469158 PMID:15307896
RGD:13792664 RGD:5509821
NCBI chrNW_004955520:1,287,829...1,315,318
Ensembl chrNW_004955520:1,286,356...1,315,328
G
Casp3
caspase 3
severity
ISO
protein:increased expression:cerebral cortex
RGD
PMID:15307896 PMID:27614125
RGD:329961568 RGD:5509821
NCBI chrNW_004955403:24,315,712...24,326,271
G
Casp8
caspase 8
disease_progression severity
ISO
RGD
PMID:12172380 PMID:15307896
RGD:5509821 RGD:632018
NCBI chrNW_004955403:322,082...348,591
Ensembl chrNW_004955403:322,555...347,053
G
Casp9
caspase 9
severity disease_progression
ISO
RGD
PMID:12172380 PMID:15307896
RGD:5509821 RGD:632018
NCBI chrNW_004955527:2,613,691...2,630,217
Ensembl chrNW_004955527:2,613,683...2,629,738
G
Ccng1
cyclin G1
treatment
ISO
RGD
PMID:18612315 PMID:24398934
RGD:151356934 RGD:151356935
NCBI chrNW_004955408:16,846,050...16,850,365
G
Cd8a
CD8 subunit alpha
ISO
mRNA:increased expression:brain (mouse)
RGD
PMID:31383034
RGD:124715446
NCBI chrNW_004955424:952,595...979,159
Ensembl chrNW_004955424:952,502...978,636
G
Cit
citron rho-interacting serine/threonine kinase
ISO
mRNA:decreased expression:cerebral cortex��(rat)
RGD
PMID:12503083
RGD:2317873
NCBI chrNW_004955455:11,705,015...11,871,762
Ensembl chrNW_004955455:11,704,964...11,872,419
G
Ctnnb1
catenin beta 1
treatment
ISO
RGD
PMID:26296359
RGD:597538582
NCBI chrNW_004955420:29,030,716...29,047,447
Ensembl chrNW_004955420:29,030,716...29,047,449
G
Cxcl10
C-X-C motif chemokine ligand 10
treatment
ISO
RGD
PMID:26435412
RGD:27095897
NCBI chrNW_004955433:748,392...750,890
Ensembl chrNW_004955433:748,284...750,927
G
Cxcl12
C-X-C motif chemokine ligand 12
ISO
protein:increased expression:cerebral cortex
RGD
PMID:27614125
RGD:329961568
NCBI chrNW_004955546:1,929,269...1,941,690
Ensembl chrNW_004955546:1,929,269...1,941,690
G
Drd1
dopamine receptor D1
treatment
ISO
RGD
PMID:24047867
RGD:13506948
NCBI chrNW_004955408:28,003,229...28,006,595
Ensembl chrNW_004955408:28,003,229...28,006,595
G
Drd2
dopamine receptor D2
treatment
ISO
RGD
PMID:24047867
RGD:13506948
NCBI chrNW_004955412:15,054,255...15,114,558
Ensembl chrNW_004955412:15,054,038...15,114,573
G
Fto
FTO alpha-ketoglutarate dependent dioxygenase
ISO
mRNA:decreased expression:cerebral cortex
RGD
PMID:31992337
RGD:329901857
NCBI chrNW_004955433:11,424,069...11,834,955
Ensembl chrNW_004955433:11,424,176...11,813,771
G
Fubp1
far upstream element binding protein 1
ISO
RGD
PMID:23797733
RGD:13673879
NCBI chrNW_004955423:15,245,645...15,278,628
Ensembl chrNW_004955423:15,245,610...15,278,628
G
Gnal
G protein subunit alpha L
ISO
RGD
PMID:29215295
RGD:13513923
NCBI chrNW_004955402:1,182,515...1,249,301
Ensembl chrNW_004955402:1,181,133...1,248,616
G
Gria1
glutamate ionotropic receptor AMPA type subunit 1
ISO
protein:increased phosphorylation:central amygdaloid nucleus (rat)
RGD
PMID:30638118
RGD:405101698
NCBI chrNW_004955408:7,912,223...8,226,241
Ensembl chrNW_004955408:7,912,592...8,223,570
G
Icam1
intercellular adhesion molecule 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28642177
NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
G
Il1b
interleukin 1 beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28642177
NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
G
Itgb1
integrin subunit beta 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25668593
NCBI chrNW_004955462:4,454,809...4,483,227
Ensembl chrNW_004955462:4,454,809...4,484,842
G
Lama1
laminin subunit alpha 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25668593
NCBI chrNW_004955402:4,281,415...4,397,158
Ensembl chrNW_004955402:4,285,492...4,400,348
G
Lamp2
lysosomal associated membrane protein 2
ISO
protein:increased expression:hippocampus:
RGD
PMID:28365875
RGD:13703062
NCBI chrNW_004955572:1,423,048...1,464,443
Ensembl chrNW_004955572:1,422,981...1,462,622
G
Mapt
microtubule associated protein tau
treatment
ISO
RGD
PMID:25771151 PMID:26484783 PMID:26729399 PMID:28412141
RGD:13800902 RGD:13800909 RGD:13800912 RGD:13800917
NCBI chrNW_004955478:10,222,439...10,271,439
Ensembl chrNW_004955478:10,225,823...10,271,442
G
Mettl14
methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit
ISO
mRNA:decreased expression:cerebral cortex
RGD
PMID:31992337
RGD:329901857
NCBI chrNW_004955428:21,475,981...21,507,730
Ensembl chrNW_004955428:21,475,981...21,507,730
G
Mmp2
matrix metallopeptidase 2
ISO
protein:increased expression:cerebral cortex
RGD
PMID:27614125
RGD:329961568
NCBI chrNW_004955433:13,024,844...13,050,041
Ensembl chrNW_004955433:13,024,418...13,052,775
G
Mmp9
matrix metallopeptidase 9
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25668593
NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288
G
Mpo
myeloperoxidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25668593
NCBI chrNW_004955451:4,743,744...4,753,358
Ensembl chrNW_004955451:4,743,744...4,753,358
G
Ncstn
nicastrin
ISO
RGD
PMID:18240300
RGD:13801189
NCBI chrNW_004955468:12,111,078...12,126,404
Ensembl chrNW_004955468:12,111,078...12,127,033
G
Nfe2l2
NFE2 like bZIP transcription factor 2
ISO
protein:increased expression:brain:
RGD
PMID:30855558
RGD:26884463
NCBI chrNW_004955403:19,510,122...19,536,428
Ensembl chrNW_004955403:19,532,103...19,535,944
G
Ngf
nerve growth factor
treatment
ISO
RGD
PMID:26285082
RGD:402463964
NCBI chrNW_004955435:18,581,889...18,633,330
Ensembl chrNW_004955435:18,581,808...18,601,059
G
Nmnat1
nicotinamide nucleotide adenylyltransferase 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:27822499
NCBI chrNW_004955486:3,637,794...3,655,744
Ensembl chrNW_004955486:3,637,794...3,655,598
G
Nos2
nitric oxide synthase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28642177
NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961
G
Nox1
NADPH oxidase 1
ISO
protein:increased expression:cerebral cortex
RGD
PMID:27614125
RGD:329961568
NCBI chrNW_004955503:6,973,965...7,020,182
Ensembl chrNW_004955503:6,974,239...6,997,618
G
Nr3c1
nuclear receptor subfamily 3 group C member 1
ISO
protein:increased phosphorylation:amygdala mRNA:decreased expression:hippocampus, hypothalamus
RGD
PMID:30638118 PMID:36637480
RGD:405101698 RGD:408364984
NCBI chrNW_004955415:10,494,704...10,585,778
Ensembl chrNW_004955415:10,494,640...10,586,221
G
Ntrk2
neurotrophic receptor tyrosine kinase 2
ISO
mRNA:increased expression:dentate gyrus
RGD
PMID:10925157
RGD:596936229
NCBI chrNW_004955432:2,284,283...2,629,631
Ensembl chrNW_004955432:2,288,898...2,630,878
G
Ocln
occludin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25668593
NCBI chrNW_004955575:163,646...210,379
G
Parp1
poly(ADP-ribose) polymerase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15829224 PMID:28642177
NCBI chrNW_004955489:520,875...557,609
Ensembl chrNW_004955489:520,875...557,615
G
Pde10a
phosphodiesterase 10A
ISO
RGD
PMID:29215295
RGD:13513923
NCBI chrNW_004955439:16,114,530...16,370,648
Ensembl chrNW_004955439:16,114,530...16,365,146
G
Pdyn
prodynorphin
ISO
mRNA:increased expression:hippocampus
RGD
PMID:12626770
RGD:633616
NCBI chrNW_004955415:13,106,087...13,119,497
Ensembl chrNW_004955415:13,106,062...13,119,515
G
Phactr1
phosphatase and actin regulator 1
treatment
ISO
RGD
PMID:36571365
RGD:401901253
NCBI chrNW_004955465:1,395,418...1,915,820
Ensembl chrNW_004955465:1,395,088...1,913,847
G
Ppp3r1
protein phosphatase 3 regulatory subunit B, alpha
ISO
RGD
PMID:20713027
RGD:13830881
NCBI chrNW_004955424:16,624,214...16,690,783
Ensembl chrNW_004955424:16,623,917...16,690,783
G
Ppp3r2
protein phosphatase 3 regulatory subunit B, beta
ISO
RGD
PMID:20713027
RGD:13830881
NCBI chrNW_004955419:24,252,772...24,253,730
G
Psen1
presenilin 1
ISO
RGD
PMID:18240300
RGD:13801189
NCBI chrNW_004955523:2,128,529...2,210,737
Ensembl chrNW_004955523:2,128,529...2,210,737
G
Ptgs2
prostaglandin-endoperoxide synthase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28642177
NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
G
Rela
RELA proto-oncogene, NF-kB subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25668593 PMID:28642177
NCBI chrNW_004955422:19,602,930...19,612,263
Ensembl chrNW_004955422:19,603,345...19,611,516
G
Sox2
SRY-box transcription factor 2
treatment
ISO
RGD
PMID:26296359
RGD:597538582
NCBI chrNW_004955420:10,671,888...10,674,080
Ensembl chrNW_004955420:10,671,978...10,672,934
G
Tgfb1
transforming growth factor beta 1
treatment
ISO
RGD
PMID:28433746
RGD:14995478
NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441
G
Tnf
tumor necrosis factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28642177
NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
G
Tp53
tumor protein p53
treatment
ISO
RGD
PMID:27553877
RGD:14995939
NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928
G
Ube4b
ubiquitination factor E4B
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:27822499
NCBI chrNW_004955486:3,518,873...3,626,036
Ensembl chrNW_004955486:3,518,740...3,626,121
G
Wnt3a
Wnt family member 3A
treatment
ISO
RGD
PMID:26296359
RGD:597538582
NCBI chrNW_004955581:351,375...382,541
Ensembl chrNW_004955581:350,889...382,541
G
F7
coagulation factor VII
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:20370756
NCBI chrNW_004955404:685,170...692,797
Ensembl chrNW_004955404:680,594...693,665
G
Abcc8
ATP binding cassette subfamily C member 8
treatment
ISO
RGD
PMID:18854840
RGD:2325137
NCBI chrNW_004955414:32,216,243...32,289,028
Ensembl chrNW_004955414:32,216,196...32,289,053
G
Tp53
tumor protein p53
ISO
RGD
PMID:22977862
RGD:8547771
NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928
G
Adrb2
adrenoceptor beta 2
ISO
mRNA:increased expression:Vestibulocochlear nerve:
RGD
PMID:22178544
RGD:8548530
NCBI chrNW_004955415:5,515,157...5,517,198
Ensembl chrNW_004955415:5,515,697...5,516,980
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all