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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:neurotoxicity
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Accession:DOID:9007553 term browser browse the term
Definition:This disease state involves injury to the central or peripheral nervous system or damage to its function. This damage can include stroke, multiple sclerosis, encephalopathy, dementia, Alzheimer's disease, amnesia, dyskinesia, Parkinson's disease, tremor, convulsions and Guillain Barre syndrome.
Synonyms:xref: EFO:0011057


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neurotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mbp myelin basic protein treatment IEP RGD PMID:33166664 RGD:213230154 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mog myelin oligodendrocyte glycoprotein treatment IEP RGD PMID:33166664 RGD:213230154 NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474 		JBrowse link
G Myrf myelin regulatory factor treatment IEP RGD PMID:33166664 RGD:213230154 NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157 		JBrowse link
G Plp1 proteolipid protein 1 treatment IEP RGD PMID:33166664 RGD:213230154 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19099
    Chemically-Induced Disorders 1420
      Drug-Related Side Effects and Adverse Reactions 665
        neurotoxicity 4
          central nervous system toxicity 0
paths to the root