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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Dysbiosis
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Accession:DOID:9007204 term browser browse the term
Definition:Changes in quantitative and qualitative composition of MICROBIOTA. The changes may lead to altered host microbial interaction or homeostatic imbalance that can contribute to a disease state often with inflammation.
Synonyms:exact_synonym: Disbacterioses;   Disbacteriosis;   Disbioses;   Disbiosis;   Dys symbiosis;   Dys-symbioses;   Dysbacterioses;   Dysbacteriosis;   Dysbioses
 primary_id: MESH:D064806

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Dysbiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 treatment ISO RGD PMID:32227764 RGD:38549571 NCBI chrNW_004936721:1,118,376...1,125,282
Ensembl chrNW_004936721:1,118,782...1,132,308 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 ameliorates ISO RGD PMID:30354811 RGD:39939000 NCBI chrNW_004936754:1,288,891...1,293,555
Ensembl chrNW_004936754:1,288,912...1,293,427 		JBrowse link
G Il10 interleukin 10 treatment ISO RGD PMID:32227764 RGD:38549571 NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502 		JBrowse link
G Il21 interleukin 21 treatment ISO RGD PMID:32227764 RGD:38549571 NCBI chrNW_004936662:1,689,879...1,696,883
Ensembl chrNW_004936662:1,689,879...1,696,883 		JBrowse link
G LOC101973915 intestinal-type alkaline phosphatase ISO RGD PMID:28985873 RGD:14367878 NCBI chrNW_004936525:4,616,212...4,619,932 JBrowse link
G Rorc RAR related orphan receptor C treatment ISO RGD PMID:32227764 RGD:38549571 NCBI chrNW_004936580:1,997,640...2,020,649
Ensembl chrNW_004936580:1,997,640...2,020,649 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO RGD PMID:30820436 RGD:150573685 NCBI chrNW_004936530:9,312,965...9,315,593
Ensembl chrNW_004936530:9,312,965...9,316,165 		JBrowse link
G Tlr4 toll like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35390362 NCBI chrNW_004936487:6,519,140...6,532,018
Ensembl chrNW_004936487:6,518,441...6,533,095 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14615
    Pathological Conditions, Signs and Symptoms 11544
      Pathologic Processes 7250
        Dysbiosis 8
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