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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Dysbiosis
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Accession:DOID:9007204 term browser browse the term
Definition:Changes in quantitative and qualitative composition of MICROBIOTA. The changes may lead to altered host microbial interaction or homeostatic imbalance that can contribute to a disease state often with inflammation.
Synonyms:exact_synonym: Disbacterioses;   Disbacteriosis;   Disbioses;   Disbiosis;   Dys symbiosis;   Dys-symbioses;   Dysbacterioses;   Dysbacteriosis;   Dysbioses
 primary_id: MESH:D064806


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Dysbiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpi alkaline phosphatase, intestinal IMP RGD PMID:28985873 RGD:14367878 NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877 		JBrowse link
G Foxp3 forkhead box P3 treatment IEP RGD PMID:32227764 RGD:38549571 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 ameliorates IMP RGD PMID:30354811 RGD:39939000 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Gper1em1Bj G protein-coupled estrogen receptor 1; CRISPR/Cas 9 induced mutant 1, Bj ameliorates IMP RGD PMID:30354811 RGD:39939000
G Il10 interleukin 10 treatment IEP RGD PMID:32227764 RGD:38549571 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il21 interleukin 21 treatment IEP RGD PMID:32227764 RGD:38549571 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G Rorc RAR-related orphan receptor C treatment IEP RGD PMID:32227764 RGD:38549571 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO RGD PMID:30820436 RGD:150573685 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35390362 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19100
    Pathological Conditions, Signs and Symptoms 13604
      Pathologic Processes 8260
        Dysbiosis 10
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