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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Dysbiosis
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Accession:DOID:9007204 term browser browse the term
Definition:Changes in quantitative and qualitative composition of MICROBIOTA. The changes may lead to altered host microbial interaction or homeostatic imbalance that can contribute to a disease state often with inflammation.
Synonyms:exact_synonym: Disbacterioses;   Disbacteriosis;   Disbioses;   Disbiosis;   Dys symbiosis;   Dys-symbioses;   Dysbacterioses;   Dysbacteriosis;   Dysbioses
 primary_id: MESH:D064806


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Dysbiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpi alkaline phosphatase, intestinal ISO RGD PMID:28985873 RGD:14367878 NCBI chrNW_004624843:5,237,041...5,239,806 JBrowse link
G Foxp3 forkhead box P3 treatment ISO RGD PMID:32227764 RGD:38549571 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 ameliorates ISO RGD PMID:30354811 RGD:39939000 NCBI chrNW_004624740:26,627,560...26,632,483
Ensembl chrNW_004624740:26,627,473...26,632,027
JBrowse link
G Il10 interleukin 10 treatment ISO RGD PMID:32227764 RGD:38549571 NCBI chrNW_004624807:4,687,249...4,691,658
Ensembl chrNW_004624807:4,687,176...4,691,732
JBrowse link
G Il21 interleukin 21 treatment ISO RGD PMID:32227764 RGD:38549571 NCBI chrNW_004624777:3,054,368...3,061,304
Ensembl chrNW_004624777:3,054,368...3,061,304
JBrowse link
G Rorc RAR related orphan receptor C treatment ISO RGD PMID:32227764 RGD:38549571 NCBI chrNW_004624772:19,478,403...19,501,184
Ensembl chrNW_004624772:19,477,093...19,501,169
JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO RGD PMID:30820436 RGD:150573685 NCBI chrNW_004624824:8,444,877...8,446,628 JBrowse link
G Tlr4 toll like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35390362 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14208
    Pathological Conditions, Signs and Symptoms 11236
      Pathologic Processes 7054
        Dysbiosis 8
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