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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Dysbiosis
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Accession:DOID:9007204 term browser browse the term
Definition:Changes in quantitative and qualitative composition of MICROBIOTA. The changes may lead to altered host microbial interaction or homeostatic imbalance that can contribute to a disease state often with inflammation.
Synonyms:exact_synonym: Disbacterioses;   Disbacteriosis;   Disbioses;   Disbiosis;   Dys symbiosis;   Dys-symbioses;   Dysbacterioses;   Dysbacteriosis;   Dysbioses
 primary_id: MESH:D064806


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Dysbiosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpi alkaline phosphatase, intestinal ISO RGD PMID:28985873 RGD:14367878 NCBI chr 1:87,025,724...87,029,328
Ensembl chr 1:87,025,724...87,029,328 		JBrowse link
G Foxp3 forkhead box P3 treatment ISO RGD PMID:32227764 RGD:38549571 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 ameliorates ISO RGD PMID:30354811 RGD:39939000 NCBI chr 5:139,408,905...139,413,555
Ensembl chr 5:139,408,906...139,413,555 		JBrowse link
G Il10 interleukin 10 treatment ISO RGD PMID:32227764 RGD:38549571 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il21 interleukin 21 treatment ISO RGD PMID:32227764 RGD:38549571 NCBI chr 3:37,276,908...37,286,785
Ensembl chr 3:37,276,908...37,286,785 		JBrowse link
G Rorc RAR-related orphan receptor gamma treatment ISO RGD PMID:32227764 RGD:38549571 NCBI chr 3:94,280,106...94,305,583
Ensembl chr 3:94,280,101...94,305,583 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 IMP RGD PMID:30820436 RGD:150573685 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400 		JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35390362 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16225
    Pathological Conditions, Signs and Symptoms 12631
      Pathologic Processes 7995
        Dysbiosis 8
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