Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Myocardial Ischemia
go back to main search page
Accession:DOID:9007102 term browser browse the term
Definition:A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Synonyms:exact_synonym: Ischemic Heart Disease;   Ischemic Heart Diseases;   Myocardial Ischemias
 related_synonym: Ischemic heart disease, susceptibility to;   SUPEROXIDE DISMUTASE, ELEVATED EXTRACELLULAR
 primary_id: MESH:D017202
 xref: EFO:1001375



show annotations for term's descendants           Sort by:
Myocardial Ischemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot2 acyl-CoA thioesterase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Actb actin, beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Acvr1b activin A receptor type 1B IEP RGD PMID:14993131 RGD:1580888 NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:16155579 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adm adrenomedullin ISO protein:increased expression:plasma RGD PMID:15350700 RGD:1625302 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Adm2 adrenomedullin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16987513 NCBI chr 7:120,393,179...120,394,965
Ensembl chr 7:120,393,179...120,396,331
JBrowse link
G Adrb1 adrenoceptor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9554809 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9554809 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO associated with Diabetes Mellitus, Type 2;DNA:SNP:promoter:-374T>A (human) RGD PMID:15896660 RGD:8695969 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:16775501 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Ak1 adenylate kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 IDA protein:increased activity:heart RGD PMID:16567803 RGD:1626092 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IDA RGD PMID:18787169 RGD:7241592 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 susceptibility ISO associated with congestive heart failure; DNA:SNP:exon 2:34C>T (human) RGD PMID:16875916 RGD:329412475 NCBI chr 2:190,598,707...190,619,938
Ensembl chr 2:190,598,700...190,619,938
JBrowse link
G Anxa5 annexin A5 IEP RGD PMID:8056721 RGD:7241858 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Aplp2 amyloid beta precursor like protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855
JBrowse link
G Apob apolipoprotein B ISO RGD PMID:9603795 RGD:1578415 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoe apolipoprotein E susceptibility ISO DNA:polymorphism:promoter:-219G>T (human) RGD PMID:17006673 RGD:1601238 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Areg amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Axin2 axin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:22014268 RGD:10054500 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:22014268 RGD:10054500 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G C1qb complement C1q B chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 IEP protein:decreased expression:heart RGD PMID:28469787 RGD:13513983 NCBI chr 8:108,072,208...108,203,516
Ensembl chr 8:108,072,454...108,203,173
JBrowse link
G Calr calreticulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Canx calnexin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO
protein:increased expression:plasma, heart (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16214533 PMID:10068207 RGD:8549542 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccna2 cyclin A2 ISO RGD PMID:17382628 RGD:10054468 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnd1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Cd36 CD36 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd38 CD38 molecule IDA
ISO
protein:increased activity:ventricle myocardium
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:16214533 PMID:12111041 RGD:2307243 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Cd40 CD40 molecule treatment IDA RGD PMID:19565716 RGD:11352677 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd40lg CD40 ligand treatment IDA
IEP
protein:increased expression:myocardium (rat) RGD PMID:19565716 PMID:19204010 RGD:11352677, RGD:11352684 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cdh2 cadherin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Ces3a carboxylesterase 3a ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Cirbp cold inducible RNA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818
JBrowse link
G Clec10a C-type lectin domain containing 10A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:54,876,244...54,880,439
Ensembl chr10:54,876,260...54,880,435
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Crk CRK proto-oncogene, adaptor protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
JBrowse link
G Crp C-reactive protein IEP
ISO
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:11840375 PMID:21122204 RGD:5128547 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cryab crystallin, alpha B IDA RGD PMID:11945023 RGD:704398 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsc cathepsin C ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Cttnbp2 cortactin binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:46,800,975...46,964,681
Ensembl chr 4:46,800,981...46,964,631
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Dcn decorin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
JBrowse link
G Dll4 delta like canonical Notch ligand 4 treatment IEP RGD PMID:32089723 RGD:155641250 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931
JBrowse link
G Dnm1l dynamin 1-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp6 dual specificity phosphatase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10462014 PMID:11707688 PMID:16306806 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Ednra endothelin receptor type A ISO RGD PMID:14729387 RGD:1580946 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Ednrb endothelin receptor type B ISO RGD PMID:14729387 RGD:1580946 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Egr2 early growth response 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19041636 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19041636 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E IDA RGD PMID:16439989 RGD:10401145 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 IDA RGD PMID:16439989 RGD:10401145 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 IEP RGD PMID:16439989 RGD:10401145 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
JBrowse link
G Eln elastin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
JBrowse link
G Ensa endosulfine alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:183,185,552...183,192,888
Ensembl chr 2:183,185,552...183,194,847
JBrowse link
G Ephx1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29298899 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29298899 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO RGD PMID:15685397 RGD:1580988 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G F2rl1 F2R like trypsin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G F3 coagulation factor III, tissue factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16286589 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G F5 coagulation factor V ISO DNA:mutation, haplotype: :1691G>A (human) RGD PMID:19524925 RGD:4892673 NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G Fabp5 fatty acid binding protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link
G Fev FEV transcription factor, ETS family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 9:76,439,164...76,443,603
Ensembl chr 9:76,439,172...76,443,065
JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:16,654,572...16,694,628
Ensembl chr 6:16,654,614...16,694,626
JBrowse link
G Fgf1 fibroblast growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:12173832 PMID:14583313 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 IDA RGD PMID:14597563 RGD:9685466 NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278
JBrowse link
G Gas5 growth arrest specific 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr13:73,303,611...73,306,932 JBrowse link
G Gatm glycine amidinotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129
JBrowse link
G Gbp2 guanylate binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gdf1 growth differentiation factor 1 ISO protein:increased expression:Left ventricle (human) RGD PMID:25726944 RGD:11252030 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,097,314...19,112,519
JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Ghr growth hormone receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide disease_progression
treatment
IEP
ISO
mRNA,protein:increased expression:plasma,myocardia: RGD PMID:16626506 PMID:16626506 RGD:12907503, RGD:12907503 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Ghsr growth hormone secretagogue receptor IEP mRNA,protein:increased expression,increased activity:myocardia: RGD PMID:16626506 RGD:12907503 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
JBrowse link
G Gk glycerol kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Gna12 G protein subunit alpha 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255
JBrowse link
G Gpt glutamic--pyruvic transaminase IEP RGD PMID:30841448 RGD:401717562 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gstm2 glutathione S-transferase mu 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gyg1 glycogenin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:102,611,888...102,653,916
Ensembl chr 2:102,598,496...102,653,797
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hfe homeostatic iron regulator susceptibility ISO RGD PMID:11545759 RGD:1582695 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Hgf hepatocyte growth factor ISO CTD Direct Evidence: therapeutic CTD PMID:12447174 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP mRNA, protein:increased expression:myocardium (rat) RGD PMID:17335664 RGD:9068465 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hivep2 HIVEP zinc finger 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:8,358,205...8,555,993
Ensembl chr 1:8,359,289...8,555,993
JBrowse link
G Hk1 hexokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131
JBrowse link
G Hk2 hexokinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Hmgb1 high mobility group box 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hmox1 heme oxygenase 1 susceptibility ISO
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16214533 PMID:15064108 PMID:15734859 RGD:1598399, RGD:1582713 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEP protein:increased expression:heart RGD PMID:12872233 RGD:1624250 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id1 inhibitor of DNA binding 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id3 inhibitor of DNA binding 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Ifngr1 interferon gamma receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Igf1 insulin-like growth factor 1 severity ISO
IDA
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16214533 PMID:16793032 PMID:16698918 RGD:1598425, RGD:1598426 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16286589 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6st interleukin 6 cytokine family signal transducer ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
JBrowse link
G Irf1 interferon regulatory factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Itgav integrin subunit alpha V ISO RGD PMID:11997283 RGD:1582453 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Jak2 Janus kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15746188 PMID:16214533 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 IEP RGD PMID:26591689 RGD:12790977 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 IEP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16214533 PMID:9399952 PMID:26591689 RGD:1598652, RGD:12790977 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 IEP mRNA:increased expression:heart left ventricle, epicardium, endocardium (rat) RGD PMID:24705172 RGD:9831164 NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435
JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 no_association ISO RGD PMID:16155733 RGD:1581719 NCBI chr10:18,557,510...18,614,824
Ensembl chr10:18,557,904...18,565,798
JBrowse link
G Kdr kinase insert domain receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Kitlg KIT ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Klf4 KLF transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Lepr leptin receptor susceptibility ISO DNA:polymorphism: :p.Q223R (human) RGD PMID:19337797 RGD:2311129 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 ISO mRNA:increased expression:myocardium (human) RGD PMID:17343875 RGD:156451374 NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta IDA RGD PMID:12371906 RGD:629541 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 IDA RGD PMID:20550965 RGD:7243113 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
JBrowse link
G Mapk14 mitogen activated protein kinase 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983
JBrowse link
G Mb myoglobin susceptibility IDA
ISO
RGD PMID:12935692 PMID:15762290 RGD:1582426, RGD:1582393 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
JBrowse link
G Meox2 mesenchyme homeobox 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:53,856,760...53,917,467
Ensembl chr 6:53,856,758...53,917,467
JBrowse link
G Mfn1 mitofusin 1 treatment IEP RGD PMID:27491814 RGD:12910831 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
JBrowse link
G Mfn2 mitofusin 2 treatment IEP RGD PMID:27491814 RGD:12910831 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mir145 microRNA 145 ISO miRNA:decreased expression:myocardium (mouse) RGD PMID:23028672 RGD:10047368 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Mpo myeloperoxidase ISO Acute Coronary Syndrome; protein:increased expression:plasma RGD PMID:21226709 RGD:5130961 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Msn moesin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr  X:60,996,043...61,064,011
Ensembl chr  X:60,995,951...61,065,628
JBrowse link
G Msr1 macrophage scavenger receptor 1 disease_progression ISO mRNA:increased expression:blood, mononuclear cell RGD PMID:17945237 RGD:2306126 NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676
JBrowse link
G Mx1 MX dynamin like GTPase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
JBrowse link
G Ncl nucleolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
JBrowse link
G Nfkbia NFKB inhibitor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:duplication, snp:intron, cds:g.IVS4?-?+27, p.E298D (human)
ClinVar Annotator: match by term: Ischemic heart disease, susceptibility to
CTD Direct Evidence: therapeutic
ClinVar
CTD
RGD
PMID:9737779 PMID:9894802 PMID:10475066 PMID:10510054 PMID:10514107 More... RGD:7777100 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Notch1 notch receptor 1 treatment IEP RGD PMID:32089723 RGD:155641250 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Nppa natriuretic peptide A ISO CTD Direct Evidence: marker/mechanism CTD PMID:1830552 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nptn neuroplastin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 8:58,996,873...59,063,402
Ensembl chr 8:58,996,887...59,063,401
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 susceptibility ISO DNA:SNPs, haplotype:promoter:c.-115G>A, c.-840C>A (rs12221497, rs61896015) (human) RGD PMID:21903943 RGD:401842365 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase treatment IEP RGD PMID:27491814 RGD:12910831 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Pde4b phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr  X:34,700,481...34,714,309
Ensembl chr  X:34,700,409...34,714,311
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pdlim5 PDZ and LIM domain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
JBrowse link
G Penk proenkephalin treatment IEP RGD PMID:21247719 RGD:10003103 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
JBrowse link
G Pfkm phosphofructokinase, muscle ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
JBrowse link
G Pgf placental growth factor ISO RGD PMID:18192038 RGD:6483613 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Pgm1 phosphoglucomutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728
JBrowse link
G Pla2g2a phospholipase A2 group IIA ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Plcd1 phospholipase C, delta 1 IEP protein:decreased expression:heart RGD PMID:15276620 RGD:2300429 NCBI chr 8:118,795,196...118,818,186
Ensembl chr 8:118,795,201...118,818,186
JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:10908253 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr14:31,215,741...31,250,144
Ensembl chr14:31,216,165...31,250,144
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha IDA
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16214533 PMID:16214533 RGD:1580707 NCBI chr14:91,556,743...91,606,391
Ensembl chr14:91,604,121...91,606,907
JBrowse link
G Prdx6 peroxiredoxin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
JBrowse link
G Prkcd protein kinase C, delta IEP mRNA, protein:increased expression, altered phosphorylation:heart RGD PMID:16924416 RGD:1642550 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkce protein kinase C, epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Psmb5 proteasome 20S subunit beta 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440
JBrowse link
G Ptpra protein tyrosine phosphatase, receptor type, A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:117,650,146...117,759,744
Ensembl chr 3:117,650,183...117,759,728
JBrowse link
G Pygb glycogen phosphorylase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:139,611,724...139,658,521
Ensembl chr 3:139,611,749...139,663,553
JBrowse link
G Pygm glycogen phosphorylase, muscle associated IDA RGD PMID:10498852 RGD:1599991 NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368
JBrowse link
G Rab12 RAB12, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 9:106,480,301...106,506,895
Ensembl chr 9:106,480,301...106,506,910
JBrowse link
G Rab1b RAB1B, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:202,405,759...202,413,850
Ensembl chr 1:202,405,759...202,413,868
Ensembl chr  X:202,405,759...202,413,868
JBrowse link
G Rab5a RAB5A, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873
JBrowse link
G Rab7a RAB7A, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889
JBrowse link
G Ralbp1 ralA binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 9:105,456,425...105,493,235
Ensembl chr 9:105,456,425...105,492,707
JBrowse link
G Ramp2 receptor activity modifying protein 2 IEP mRNA:increased expression:ventricle myocardium RGD PMID:16987513 RGD:1642684 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
JBrowse link
G Rgcc regulator of cell cycle ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
JBrowse link
G Rhoc ras homolog family member C ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
JBrowse link
G Rln3 relaxin 3 ISO CTD Direct Evidence: therapeutic CTD PMID:16112403 NCBI chr19:24,107,401...24,109,432
Ensembl chr19:24,107,401...24,109,886
JBrowse link
G Rpl17 ribosomal protein L17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr18:68,581,141...68,584,253
Ensembl chr18:68,581,098...68,584,253
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
JBrowse link
G RT1-A2 RT1 class Ia, locus A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-N3 RT1 class Ib, locus N3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr20:2,659,132...2,665,536
Ensembl chr20:2,661,584...2,665,530
JBrowse link
G Rtn1 reticulon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:90,763,212...90,983,436
Ensembl chr 6:90,763,216...90,983,436
JBrowse link
G Rxrg retinoid X receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
JBrowse link
G Ryr2 ryanodine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G S100a1 S100 calcium binding protein A1 ISO protein:increased expression:serum (human) RGD PMID:10924368 RGD:1579977 NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544
JBrowse link
G Sele selectin E ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Selp selectin P ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
JBrowse link
G Serpina1 serpin family A member 1 ISO associated with Aortic Aneurysm, Abdominal;DNA:polymorphism: :p.E342K (human) RGD PMID:10063411 RGD:1643148 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
JBrowse link
G Serpinf1 serpin family F member 1 ISO associated with chronic kidney disease;protein:increased expression:blood (human) RGD PMID:11045282 RGD:30296653 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link
G Sfrp4 secreted frizzled-related protein 4 IEP RGD PMID:20528676 RGD:4107721 NCBI chr17:45,278,867...45,330,806
Ensembl chr17:45,234,097...45,330,736
JBrowse link
G Slc6a6 solute carrier family 6 member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
JBrowse link
G Slc8a1 solute carrier family 8 member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628
JBrowse link
G Slc9a1 solute carrier family 9 member A1 IDA RGD PMID:17356886 RGD:1625560 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
JBrowse link
G Snap23 synaptosome associated protein 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 3:107,514,088...107,546,177
Ensembl chr 3:107,514,131...107,544,320
JBrowse link
G Socs3 suppressor of cytokine signaling 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16214533 PMID:15681709 RGD:1581233 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sod3 superoxide dismutase 3 IDA
ISO
ClinVar Annotator: match by term: Superoxide dismutase, elevated extracellular ClinVar
RGD
PMID:7662997 PMID:8034674 PMID:14662715 PMID:25741868 PMID:16840738 RGD:1580843 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sox2 SRY-box transcription factor 2 IMP RGD PMID:34321385 RGD:155882552 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338
JBrowse link
G Sparc secreted protein acidic and cysteine rich ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
JBrowse link
G Stat5a signal transducer and activator of transcription 5A ISO CTD Direct Evidence: marker/mechanism CTD PMID:15746188 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
JBrowse link
G Tcf7l2 transcription factor 7 like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29394407 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
G Tfrc transferrin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tgoln2 trans-golgi network protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 4:104,663,356...104,671,208
Ensembl chr 4:104,663,353...104,671,164
JBrowse link
G Tle4 TLE family member 4, transcriptional corepressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:211,661,738...211,798,458
Ensembl chr 1:211,661,746...211,797,862
JBrowse link
G Tle5 TLE family member 5, transcriptional modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:8,143,357...8,150,295
Ensembl chr 7:8,143,357...8,150,113
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903
JBrowse link
G Tmpo thymopoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 PMID:16775501 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnnt2 troponin T2, cardiac type ISO CTD Direct Evidence: marker/mechanism CTD PMID:10789933 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
JBrowse link
G Ttn titin IDA RGD PMID:12221049 RGD:1580780 NCBI chr 3:61,652,432...61,924,912
Ensembl chr 3:61,652,439...61,924,741
JBrowse link
G Tuba1a tubulin, alpha 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186
JBrowse link
G Txnip thioredoxin interacting protein IDA RGD PMID:16172122 RGD:1580789 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Txnrd1 thioredoxin reductase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr17:33,977,908...33,982,478
Ensembl chr17:33,977,921...33,982,479
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:9860779 PMID:14503966 PMID:14583313 PMID:15347709 PMID:16214533 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214
JBrowse link
G Zfp36 zinc finger protein 36 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16214533 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
Acute Coronary Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actg1 actin, gamma 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO protein:increased expression:serum (human) RGD PMID:21663912 RGD:5508825 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Alb albumin treatment ISO RGD PMID:20716836 RGD:11036086 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409
JBrowse link
G Ccn1 cellular communication network factor 1 susceptibility ISO DNA:SNP,haplotypes:5'utr: (rs6576776) (human) RGD PMID:33906697 RGD:329845569 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Cd40 CD40 molecule ISO DNA:SNP:5' utr:rs1883832 (human) RGD PMID:21091218 RGD:5490523 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd40lg CD40 ligand treatment ISO associated with Anxiety Disorders;protein:increased expression:serum RGD PMID:20170788 PMID:31624788 RGD:5490548, RGD:21081509 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Ckb creatine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15966572 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Ckm creatine kinase, M-type ISO CTD Direct Evidence: marker/mechanism CTD PMID:15966572 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Crp C-reactive protein ISO CTD Direct Evidence: marker/mechanism
protein:increased expression: :
CTD
RGD
PMID:15966572 PMID:23305094 PMID:18973750 PMID:21794939 RGD:6907401, RGD:9491837 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 treatment ISO ClinVar Annotator: match by term: Acute coronary syndrome
DNA:SNPs::CYP2C19*2 (681G>A,rs4244285), CYP2C19*17 (-806C>T, rs12248560) (human)
ClinVar
RGD
PMID:7969038 PMID:9093256 PMID:19444287 PMID:21270786 PMID:27441996 More... RGD:401960861 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G F12 coagulation factor XII ISO ClinVar Annotator: match by term: FACTOR XII POLYMORPHISM ClinVar PMID:9490684 PMID:11843842 PMID:20303064 PMID:24033266 PMID:25741868 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:21496882 RGD:5147784 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23305094 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase susceptibility ISO DNA:SNP: :rs17817449 (human) RGD PMID:20362563 RGD:329813083 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO DNa:SNP: :rs3783637 (human) RGD PMID:26232608 RGD:329961571 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Gp6 glycoprotein VI disease_progression ISO protein:increased expression:platelet (human) RGD PMID:17340467 PMID:20071043 RGD:401794408, RGD:401824680 NCBI chr 1:69,429,232...69,492,709
Ensembl chr 1:69,465,789...69,491,326
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO mRNA, protein:increased expression:blood, plasma RGD PMID:28298473 RGD:401827171 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx3 glutathione peroxidase 3 ISO mRNA, protein:increased expression:blood, plasma RGD PMID:28298473 RGD:401827171 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Gpx4 glutathione peroxidase 4 ISO mRNA, protein:increased expression:blood, plasma RGD PMID:28298473 RGD:401827171 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Gsn gelsolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO DNA:SNP: :190G>C(human) RGD PMID:21849784 RGD:7257650 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Il6 interleukin 6 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression:blood serum (human)
CTD
RGD
PMID:23305094 PMID:32178736 PMID:32178736 RGD:155230830, RGD:155230830 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgb3 integrin subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15840736 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Ldhb lactate dehydrogenase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
JBrowse link
G Mir126a microRNA 126a ISO RNA:decreased expression:plasma RGD PMID:27900989 RGD:401850572 NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180
JBrowse link
G Mir145 microRNA 145 disease_progression
treatment
ISO
IEP
RNA:decreased expression:blood serum (human) RGD PMID:32178736 PMID:32178736 RGD:155230830, RGD:155230830 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20981132 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase susceptibility ISO DNA:SNP,haplotype: :p.S326C (rs1052133) (human) RGD PMID:23368530 RGD:401827273 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Pappa pappalysin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11586954 NCBI chr 5:78,497,660...78,735,873
Ensembl chr 5:78,498,300...78,730,666
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO protein:increased expression:coronary artery, intima (human) RGD PMID:22336504 RGD:6767292 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Phactr1 phosphatase and actin regulator 1 exacerbates ISO protein:increased expression:monocyte (human) RGD PMID:32857129 RGD:401900689 NCBI chr17:21,560,364...22,040,166
Ensembl chr17:21,562,721...22,039,831
JBrowse link
G Pla2g7 phospholipase A2 group VII disease_progression ISO RGD PMID:22024276 RGD:6482773 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26241956 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
JBrowse link
G Rab7b Rab7b, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581
JBrowse link
G Rbp4 retinol binding protein 4 severity
onset
ISO protein:increased expression:blood plasma (human)
protein:increased expression:blood serum (human)
RGD PMID:25437889 PMID:32449048 RGD:329845573, RGD:329845576 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
JBrowse link
G S100b S100 calcium binding protein B ISO protein:increased expression:serum RGD PMID:21663912 RGD:5508825 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
JBrowse link
G Serpinc1 serpin family C member 1 ISO CTD Direct Evidence: therapeutic CTD PMID:7923645 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20981132 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor treatment ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression:blood serum (human)
CTD
RGD
PMID:20981132 PMID:32178736 PMID:32178736 RGD:155230830, RGD:155230830 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnni3 troponin I3, cardiac type ISO CTD Direct Evidence: marker/mechanism CTD PMID:15966572 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580
JBrowse link
G Tnnt2 troponin T2, cardiac type ISO CTD Direct Evidence: marker/mechanism CTD PMID:15966572 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
JBrowse link
G Tpm4 tropomyosin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
JBrowse link
G Tuba1c tubulin, alpha 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647
JBrowse link
G Tubb1 tubulin, beta 1 class VI ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr 3:163,247,990...163,257,460
Ensembl chr 3:163,247,967...163,256,063
JBrowse link
G Vcl vinculin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
JBrowse link
G Vim vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21751358 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
acute myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap17 Rho GTPase activating protein 17 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 1:177,807,579...177,897,027
Ensembl chr 1:177,807,583...177,896,854
JBrowse link
G Bax BCL2 associated X, apoptosis regulator ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G C3 complement C3 ISO RGD PMID:26476955 RGD:11552746 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 ISO mRNA:decreased expression:blood: RGD PMID:27746059 RGD:13524557 NCBI chr10:92,683,778...92,745,842
Ensembl chr10:92,683,761...92,746,126
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:26550220 RGD:13782284 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 treatment IEP RGD PMID:26550220 RGD:13782284 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Ccn1 cellular communication network factor 1 ameliorates ISO RGD PMID:30371213 RGD:329845516 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Dsc2 desmocollin 2 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392
JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase ISO mRNA:increased expression:blood RGD PMID:35693610 RGD:329901852 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083
JBrowse link
G Gata5 GATA binding protein 5 susceptibility ISO DNA:SNPs:promoter:rs80197101, rs77067995 (human) RGD PMID:33684162 RGD:155260335 NCBI chr 3:167,418,563...167,426,751
Ensembl chr 3:167,418,565...167,426,751
JBrowse link
G Gp6 glycoprotein VI ameliorates
sexual_dimorphism
ISO DNA:missense mutation:CDS:p.S219P (rs1613662) (human)
DNA:missense mutation:intron 1, intron 5: (rs1671207, rs11084382) (human)
RGD PMID:20227257 PMID:20227257 RGD:401794138, RGD:401794138 NCBI chr 1:69,429,232...69,492,709
Ensembl chr 1:69,465,789...69,491,326
JBrowse link
G Gpx3 glutathione peroxidase 3 ISO protein:increased expression:plasma RGD PMID:28374671 RGD:401827832 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment
ameliorates
IEP RGD PMID:26591365 PMID:32068187 RGD:13792778, RGD:267358468 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G H19 H19 imprinted maternally expressed transcript ameliorates IMP RGD PMID:31755219 RGD:213230161 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 ISO ClinVar Annotator: match by term: Acute myocardial infarction ClinVar PMID:20946881 PMID:21250968 PMID:21596855 PMID:21997850 PMID:22160010 More... NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Ifng interferon gamma ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Il10 interleukin 10 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il17a interleukin 17A ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1b interleukin 1 beta ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 IEP RGD PMID:24837094 RGD:40813741 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
JBrowse link
G Il33 interleukin 33 IEP RGD PMID:24837094 RGD:40813741 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il4 interleukin 4 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgam integrin subunit alpha M treatment ISO RGD PMID:21238619 RGD:329901664 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Kif6 kinesin family member 6 ISO DNA:SNP: :p.W719R (rs20455) (human) RGD PMID:20044086 RGD:243048455 NCBI chr 9:11,076,203...11,373,205
Ensembl chr 9:11,072,824...11,373,006
JBrowse link
G Mir126a microRNA 126a disease_progression ISO RGD PMID:36523365 PMID:32595526 RGD:401851047, RGD:401851053 NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180
JBrowse link
G Mir146a microRNA 146a ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir17 microRNA 17 treatment IMP RGD PMID:29536180 RGD:329403057 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir21 microRNA 21 ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma
RNA:decreased expression:serum
RGD PMID:31866771 PMID:32595526 RGD:21081515, RGD:401851053 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir223 microRNA 223 treatment IMP RGD PMID:29689569 RGD:25823140 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996
JBrowse link
G Mir320a microRNA 320a ISO RGD PMID:29990866 RGD:155882565 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 ameliorates IEP associated with obesity RGD PMID:35257523 RGD:401794445 NCBI chr 2:115,519,248...115,533,589
Ensembl chr 2:115,519,154...115,533,589
JBrowse link
G Pf4 platelet factor 4 treatment IEP RGD PMID:29407168 RGD:329901925 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Plcg1 phospholipase C, gamma 1 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Ppbp pro-platelet basic protein treatment IEP RGD PMID:29407168 RGD:329901925 NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
JBrowse link
G Pten phosphatase and tensin homolog ameliorates IEP
ISO
mRNA:decreased expression:heart left ventricle (rat)
RNA:increased expression:serum
RGD PMID:26973267 PMID:32595526 PMID:29990866 RGD:11526378, RGD:401851053, RGD:155882565 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Rhoa ras homolog family member A ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rit2 Ras-like without CAAX 2 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr18:22,565,403...22,921,648
Ensembl chr18:22,565,404...22,921,648
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B ameliorates IEP associated with obesity RGD PMID:35257523 RGD:401794445 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
JBrowse link
G Serping1 serpin family G member 1 ISO
IEP
mRNA:increased expression:heart RGD PMID:26476955 PMID:26476955 RGD:11552746, RGD:11552746 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
JBrowse link
G Tbx1 T-box transcription factor 1 treatment IEP RGD PMID:27422448 RGD:155882497 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380
JBrowse link
G Tnf tumor necrosis factor ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 ameliorates IEP RGD PMID:32068187 RGD:267358468 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214
JBrowse link
Angina Pectoris term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 ISO RGD PMID:11527135 RGD:5129114 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 ISO RGD PMID:11527135 RGD:5129114 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Avp arginine vasopressin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11128043 PMID:11791009 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Cpb2 carboxypeptidase B2 ISO RGD PMID:12624641 RGD:1598479 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556
JBrowse link
G Mir146a microRNA 146a ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir21 microRNA 21 ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:1730212 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Ppbp pro-platelet basic protein ISO protein:increased expression:plasma RGD PMID:17045893 RGD:401794448 NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:16421174 RGD:1581390 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
anterolateral myocardial infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 ISO protein:increased expression:aortic root, coronary sinus, plasma (human) RGD PMID:12581682 RGD:8661757 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Serpine1 serpin family E member 1 disease_progression ISO protein:decreased expression, decreased activity:heart: RGD PMID:12615902 PMID:12615902 RGD:13208541, RGD:13208541 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
Cardiac Allograft Vasculopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor IEP RGD PMID:9916935 RGD:11341701 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:21489814 RGD:155260371 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
JBrowse link
G Pdgfd platelet derived growth factor D ISO RGD PMID:19213942 RGD:9854642 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395
JBrowse link
Cardiogenic Shock term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epo erythropoietin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19337937 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:1430592 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21062213 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
coronary aneurysm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO associated with Mucocutaneous Lymph Node Syndrome;protein:increased expression:serum RGD PMID:22683371 RGD:8694456 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Gja1 gap junction protein, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15548583 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Itpkc inositol-trisphosphate 3-kinase C ISO CTD Direct Evidence: marker/mechanism CTD PMID:18084290 NCBI chr 1:82,500,957...82,522,533
Ensembl chr 1:82,500,957...82,522,779
JBrowse link
G Mill1 MHC I like leukocyte 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10899738 NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930
JBrowse link
G Mmp12 matrix metallopeptidase 12 susceptibility ISO RGD PMID:12103254 RGD:1582363 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
coronary artery disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO RGD
GAD
PMID:11086027 PMID:15118671 RGD:1600951, RGD:1331525 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 ISO DNA:nonsense mutation:exon:p.R1141X (3421C>T) (human) RGD PMID:12176944 RGD:11038788 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11099417 PMID:11138003 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Premature coronary artery atherosclerosis
CTD
ClinVar
PMID:11099417 PMID:25741868 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 3:10,162,087...10,182,835
Ensembl chr 3:10,162,096...10,191,423
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 susceptibility ISO DNA:polymorphisms: :41A>G, 734C>T, IVS4-57_58ins48bp RGD PMID:16195894 RGD:1601112 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:deletion:intron:IVS16+1464-1751del (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:14989558 PMID:12975417 PMID:15118671 RGD:1566498, RGD:1331525 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Acp1 acid phosphatase 1 ISO RGD PMID:19246900 RGD:2313179 NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021
JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 8:90,704,727...90,744,333
Ensembl chr 8:90,704,727...90,744,328
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing susceptibility ISO protein:decreased expression:adipose tissue
associated with type 2 diabetes mellitus; DNA:SNP: (rs2241766) +45T>G(human)
RGD PMID:17878891 PMID:27218147 RGD:5686802, RGD:329956419 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adrb3 adrenoceptor beta 3 no_association ISO DNA:missense mutation:cds:p.W64R (human)
DNA:missense mutation:cds:p.W64R rs4994 (human)
RGD PMID:9126344 PMID:11229427 RGD:1559325, RGD:5684412 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378986 NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826
JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility ISO DNA:polymorphism:cds:p.G82S (human)
associated with Mucocutaneous Lymph Node Syndrome
RGD PMID:20668462 PMID:22337222 RGD:6767569, RGD:8695960 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Agt angiotensinogen ISO GAD PMID:15118671 RGD:1331525 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a susceptibility ISO DNA:polymorphism:3' utr:1166A>C RGD
GAD
PMID:12975417 PMID:15118671 RGD:1566498, RGD:1331525 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 ISO DNA:missense mutation:cds:rs37369, rs16899974 (human) RGD PMID:30284143 RGD:329961317 NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926
JBrowse link
G Ahsg alpha-2-HS-glycoprotein susceptibility ISO associated with Diabetes Mellitus, Type 2;DNA:SNPs RGD PMID:17062776 PMID:17062776 RGD:1625792, RGD:1625792 NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO RGD PMID:18054314 RGD:5509083 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO DNA:snps:multiple (human) RGD PMID:19596330 RGD:2313883 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 susceptibility ISO DNA:SNP:exon 2:34C>T (human) RGD PMID:11028479 RGD:329349360 NCBI chr 2:190,598,707...190,619,938
Ensembl chr 2:190,598,700...190,619,938
JBrowse link
G Angptl4 angiopoietin-like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27135400 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Anks1a ankyrin repeat and sterile alpha motif domain containing 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr20:5,963,658...6,117,139
Ensembl chr20:5,963,678...6,117,148
JBrowse link
G Apcs amyloid P component, serum ISO CTD Direct Evidence: marker/mechanism CTD PMID:12714198 NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298
JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit ISO DNA:SNP:CDS:p.F217L (rs1047552) (human) RGD PMID:18987747 RGD:13703124 NCBI chr 8:67,429,198...67,454,735
Ensembl chr 8:67,429,198...67,450,243
JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:27135400 PMID:2128269 PMID:15118671 RGD:1601188, RGD:1331525 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 ISO protein:decreased expression:serum RGD PMID:17923573 RGD:2313956 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa5 apolipoprotein A5 no_association ISO DNA:polymorphism:promoter:-1131T>C (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:-1131T>C, c.56C>G (human)
CTD
RGD
PMID:24097064 PMID:15177130 PMID:15306190 RGD:2313322, RGD:1578412 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Apob apolipoprotein B no_association ISO DNA:SNP:CDS:rs1042031 (human) RGD
GAD
PMID:9585673 PMID:28167353 PMID:15118671 PMID:1732399 RGD:1578418, RGD:329901772, RGD:1331525, RGD:1578417 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoc3 apolipoprotein C3 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:24097064 PMID:14709372 PMID:15118671 PMID:15059615 RGD:1578443, RGD:1331525, RGD:1626412 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Apoe apolipoprotein E susceptibility ISO
IMP
DNA:snp, missense mutation:promoter, cds:g.-219G>T, p.C112R (human)
associated with Diabetes Mellitus, Non-Insulin Dependent;DNA:SNP:promoter:-219G>T (human)
DNA:missense mutation:cds:p.C112R (human)
RGD
GAD
PMID:14563588 PMID:28808185 PMID:15118671 PMID:15059615 PMID:12860263 RGD:1580039, RGD:13703132, RGD:1331525, RGD:1626412, RGD:1578449 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apom apolipoprotein M susceptibility ISO DNA:SNP:promoter:g.-778T>C(rs805296)(human) RGD PMID:17674965 RGD:2314241 NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550
JBrowse link
G Ar androgen receptor ISO GAD PMID:15118671 RGD:1331525 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arhgap31 Rho GTPase activating protein 31 susceptibility ISO associated with nicotine dependence;DNA:SNP: (rs10934490) (human) RGD PMID:19706030 RGD:329970276 NCBI chr11:62,038,635...62,151,564
Ensembl chr11:62,038,635...62,151,564
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22751097 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
JBrowse link
G Bche butyrylcholinesterase susceptibility ISO DNA:polymorphism: :p.A539T (human) RGD PMID:17852836 RGD:2306777 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Brinp3 BMP/retinoic acid inducible neural specific 3 ISO DNA:SNP: :rs12732361(human), associated with male. RGD PMID:27461004 RGD:14398490 NCBI chr13:58,413,883...58,846,828
Ensembl chr13:58,413,883...58,846,770
JBrowse link
G Btnl2 butyrophilin-like 2 susceptibility ISO associated with Mucocutaneous Lymph Node Syndrome; DNA:SNP: :rs 2395158(human) RGD PMID:19882345 RGD:9685030 NCBI chr20:4,490,169...4,504,002
Ensembl chr20:4,489,517...4,503,341
JBrowse link
G C5h1orf167 similar to human chromosome 1 open reading frame 167 ISO DNA:SNP: :rs56001051(human) RGD PMID:31175347 RGD:14696712 NCBI chr 5:158,495,514...158,505,671 JBrowse link
G Carf calcium responsive transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 9:61,502,368...61,552,433
Ensembl chr 9:61,506,956...61,550,462
JBrowse link
G Cbs cystathionine beta synthase ISO CBS variant c.844ins68 RGD PMID:12855221 RGD:1600626 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO
protein:increased expression:myocardium (rat)
ClinVar Annotator: match by term: Coronary artery disease, modifier of
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum (human)
ClinVar
CTD
RGD
PMID:11500196 PMID:15466648 PMID:16352737 PMID:16596675 PMID:16934270 More... RGD:8549513, RGD:8549577 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl26 C-C motif chemokine ligand 26 susceptibility ISO protein:decreased expression:plasma (human) RGD PMID:16620281 RGD:11081161 NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO RGD PMID:12742282 RGD:5508477 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:12426226 RGD:1581178 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:heart (rat) RGD PMID:17449418 RGD:4890438 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cd14 CD14 molecule no_association ISO DNA:SNP:promoter RGD PMID:18157711 RGD:2314154 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd36 CD36 molecule ISO ClinVar Annotator: match by term: Premature coronary artery atherosclerosis ClinVar PMID:25741868 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd40lg CD40 ligand ISO
IEP
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
associated with Mucocutaneous Lymph Node Syndrome;DNA:SNP: :rs4810485 (human)
protein:increased expression:coronary artery, serum
associated with Kidney Failure, Chronic
CTD
RGD
PMID:16368305 PMID:17635572 PMID:22645426 PMID:23819214 PMID:16494885 RGD:2314209, RGD:8547776, RGD:7248750, RGD:7248436 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cdh5 cadherin 5 ISO RGD PMID:14695457 RGD:1598391 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23104008 PMID:34961328 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cela2a chymotrypsin like elastase 2A ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:25741868 PMID:31358993 NCBI chr 5:154,126,879...154,136,630
Ensembl chr 5:154,126,878...154,136,632
JBrowse link
G Celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 2:196,029,206...196,053,848
Ensembl chr 2:196,029,434...196,053,845
JBrowse link
G Chi3l1 chitinase 3 like 1 ISO protein:increased secretion:serum (human) RGD PMID:17627189 RGD:4892665 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Clcn6 chloride voltage-gated channel 6 susceptibility ISO DNA:SNP: :rs3737964(human) RGD PMID:26740945 RGD:14696742 NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
JBrowse link
G Clu clusterin ISO associated with Mucocutaneous Lymph Node Syndrome;protein:decreased expression:plasma RGD PMID:20711835 RGD:9068393 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Crp C-reactive protein ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:24868163 PMID:19615354 RGD:2313344 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cst3 cystatin C ISO protein:increased expression:serum (human) RGD PMID:17983622 RGD:2314352 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
G Cubn cubilin susceptibility ISO DNA:SNP,haplotypes:intron: (rs2291521)G>A (human) RGD PMID:33004870 RGD:329901841 NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cyba cytochrome b-245 alpha chain ISO RGD
GAD
PMID:14709372 PMID:15118671 RGD:1578443, RGD:1331525 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 ISO ClinVar Annotator: match by term: Premature coronary artery atherosclerosis ClinVar PMID:25741868 PMID:28492532 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 ISO DNA:SNP:CDS:rs10741657 (human) RGD PMID:25003556 RGD:401901077 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759
JBrowse link
G Dab2ip DAB2 interacting protein onset ISO DNA:SNP:CDS:rs7025486 (human) RGD PMID:30595311 RGD:401938617 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 ISO DNA:missense mutation:cds:rs997251 (human) RGD PMID:30284143 RGD:329961317 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Ddah2 DDAH family member 2, ADMA-independent ISO CTD Direct Evidence: marker/mechanism CTD PMID:17267746 NCBI chr20:3,761,460...3,764,718
Ensembl chr20:3,761,465...3,764,511
JBrowse link
G Ece1 endothelin converting enzyme 1 ISO protein:increased expression:smooth muscle cell,macrophage RGD PMID:10973835 PMID:8994440 RGD:1580909, RGD:7244168 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371
JBrowse link
G Edn1 endothelin 1 treatment
severity
ISO
IMP
protein:increased expression:atherosclerotic lesions (human)
associated with Hypertension;DNA:missense mutation:cds:p.L198N (human)
RGD PMID:7968078 PMID:11927217 PMID:18923236 RGD:4144886, RGD:8662294, RGD:8661705 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Eng endoglin severity ISO protein:increased expression:plasma (human) RGD PMID:21667051 RGD:7248776 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:14732757 RGD:1580982 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Epo erythropoietin ISO CTD Direct Evidence: therapeutic CTD PMID:25245553 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility ISO DNA:SNP: :rs13181(human) RGD PMID:27566080 RGD:12880440 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:9396482 PMID:20559769 PMID:16159931 RGD:1580335 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20559769 PMID:16099331 RGD:1581014 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G F2 coagulation factor II, thrombin treatment ISO RGD PMID:14961168 RGD:10449426 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F7 coagulation factor VII ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased activity:plasma (human)
DNA:polymorphisms:cds:R353Q (human)
RGD PMID:10599031 PMID:8522401 PMID:11334615 RGD:2312400, RGD:2312408, RGD:2312397 NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
JBrowse link
G Fabp2 fatty acid binding protein 2 ISO associated with Diabetes Mellitus, Type 2 (MeSH:D003924) RGD PMID:15059615 RGD:1626412 NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
JBrowse link
G Fcgr2a Fc gamma receptor 2A ISO DNA:polymorphism: :p.H131R (human) RGD PMID:20973705 RGD:5147917 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Fcgr3a Fc gamma receptor 3A susceptibility ISO DNA:SNP:exon:p.F158V (rs396991)(human) RGD PMID:15910853 RGD:5508464 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Fes FES proto-oncogene, tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 1:134,337,698...134,346,934
Ensembl chr 1:134,337,698...134,346,934
JBrowse link
G Fgb fibrinogen beta chain ISO RGD PMID:8565160 RGD:1580382 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO associated with Diabetes Mellitus RGD PMID:14585103 RGD:2315879 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase ISO DNA:SNP: :rs9939609 (human)
DNA:SNP:intron:rs9939609 (human)
RGD PMID:24622111 PMID:28167353 RGD:329812039, RGD:329901772 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
JBrowse link
G Gck glucokinase susceptibility ISO DNA:SNP:promoter:-30G>A (human) RGD PMID:15173029 RGD:2301876 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gdf15 growth differentiation factor 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20855664 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gfod1 Gfo/Idh/MocA-like oxidoreductase domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr17:21,400,142...21,504,972
Ensembl chr17:21,399,479...21,499,938
JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063
JBrowse link
G Gja4 gap junction protein, alpha 4 ISO RGD PMID:15059615 RGD:1626412 NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925
JBrowse link
G Gnb3 G protein subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16141801 NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173
JBrowse link
G Gp6 glycoprotein VI treatment ISO protein:increased expression:platelet (human) RGD PMID:18585516 RGD:401794134 NCBI chr 1:69,429,232...69,492,709
Ensembl chr 1:69,465,789...69,491,326
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO cardiovascular complications in type 2 diabetics
DNA:repeat:exon
RGD PMID:16338763 PMID:12655278 RGD:1600708, RGD:1600677 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx3 glutathione peroxidase 3 ISO mRNA:increased expression:epicardial fat RGD PMID:21679057 RGD:401827169 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Gsr glutathione-disulfide reductase ISO cardiovascular complications in type 2 diabetics RGD PMID:16338763 RGD:1600708 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
DNA:deletion
RGD PMID:19102712 PMID:16620396 RGD:2306625, RGD:2306633 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent
DNA:deletion
RGD PMID:19102712 PMID:16620396 RGD:2306625, RGD:2306633 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22751097 NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671
JBrowse link
G H19 H19 imprinted maternally expressed transcript susceptibility ISO DNA:SNPs,haplotype:intron: (rs2735971,rs2839698,rs3024270) (human) RGD PMID:32454910 RGD:242905209 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
JBrowse link
G Hectd4 HECT domain E3 ubiquitin protein ligase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22751097 NCBI chr12:35,182,165...35,330,935
Ensembl chr12:35,182,154...35,330,987
JBrowse link
G Hfe homeostatic iron regulator no_association ISO RGD PMID:12746412 RGD:1582673 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Hgf hepatocyte growth factor ISO RGD PMID:11669408 RGD:8548610 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hhipl1 HHIP-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 6:127,219,616...127,243,839
Ensembl chr 6:127,220,014...127,242,564
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:12742282 RGD:5508477 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 no_association
susceptibility
ISO DNA:repeat:promoter
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:12136229 PMID:14691581 PMID:12377749 PMID:12136229 RGD:1580470, RGD:1580454, RGD:1598401 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf1a HNF1 homeobox A susceptibility ISO DNA:SNP:intron 1: (rs7310409) G>A (human)
DNA:SNP,haplotypes:intron: (rs55783344) C>T(human)
DNA:SNPs,haplotypes:multiple
RGD PMID:25202455 PMID:33004870 PMID:28035729 RGD:329901832, RGD:329901841, RGD:329901837 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hp haptoglobin ISO protein:increased expression:serum RGD PMID:884791 RGD:1626363 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Hs3st1 heparan sulfate-glucosamine 3-sulfotransferase 1 ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:15266341 PMID:15965027 PMID:16024819 PMID:16410828 PMID:17179217 More... NCBI chr14:71,185,826...71,223,263
Ensembl chr14:71,185,682...71,223,248
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 sexual_dimorphism ISO associated with obesity;mRNA,protein:increased expression:multiple (human) RGD PMID:23009206 RGD:329901914 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 severity ISO RGD PMID:11222468 RGD:1624218 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Ica1l islet cell autoantigen 1-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 9:61,410,959...61,469,884
Ensembl chr 9:61,412,091...61,470,134
JBrowse link
G Il10 interleukin 10 no_association
susceptibility
ISO DNA:SNPs:promoter:-592C>A (rs1800872), -819C>T (rs1800871) (human)
DNA:SNP:promoter:-1082A>G (rs1800896) (human)
RGD PMID:16460885 PMID:29525679 PMID:29525679 RGD:1598621, RGD:14975129, RGD:14975129 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il15 interleukin 15 ISO associated with Hypertension;protein:increased expression:serum RGD PMID:16109314 RGD:1626610 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il1b interleukin 1 beta ISO mRNA:increased expression:peripheral blood (human) RGD PMID:22780915 RGD:7175093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 severity ISO DNA:polymorphisms: :-27307T>A, -27614C>A (human) RGD PMID:20602249 RGD:5144241 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
JBrowse link
G Il6 interleukin 6 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human) RGD PMID:19368923 RGD:2307251 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521
JBrowse link
G Irs1 insulin receptor substrate 1 ISO DNA:polymorphism:exon:G972R
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:10591678 PMID:10591678 RGD:1624974 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Itga2 integrin subunit alpha 2 no_association ISO RGD PMID:15227729 RGD:1582294 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Jcad junctional cadherin 5 associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378988 NCBI chr17:53,089,382...53,130,996
Ensembl chr17:53,089,382...53,130,967
JBrowse link
G Kalrn kalirin, RhoGEF kinase susceptibility
onset
severity
ISO DNA:SNP:intron: (rs9289231) T>G (human)
associated with nicotine dependence; DNA:SNPs:multiple
associated with type 2 diabetes mellitus;DNA:SNP:intron: (rs9289231) T>G (human)
DNA:SNP:intron: (rs9289231) (human)
RGD PMID:30483314 PMID:19706030 PMID:27218147 PMID:25316661 RGD:329955537, RGD:329970276, RGD:329956419, RGD:11076452 NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 ISS OMIM:300464 | OMIM:607339 | OMIM:608316 | OMIM:608318 | OMIM:608320 | OMIM:608901 | OMIM:610938 | OMIM:610947 | OMIM:611139 | OMIM:612030 | OMIM:614293 | OMIM:614466 MouseDO NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
JBrowse link
G Kif6 kinesin family member 6 sexual_dimorphism
no_association
treatment
ISO DNA:SNP: :rs20455 (human)
associated with type 2 diabetes mellitus;DNA:SNP: :p.W719R (rs20455) (human)
RGD PMID:18222354 PMID:25629058 PMID:21458191 PMID:26443250 PMID:26997531 More... RGD:243048446, RGD:243048454, RGD:243048451, RGD:11527801, RGD:243048449, RGD:243048447 NCBI chr 9:11,076,203...11,373,205
Ensembl chr 9:11,072,824...11,373,006
JBrowse link
G Kl Klotho ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:promoter: -G395>A (human)
CTD
RGD
PMID:12669274 PMID:16979405 PMID:16579981 RGD:1581721, RGD:1581723 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
JBrowse link
G Ldlr low density lipoprotein receptor no_association ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21378990 PMID:27135400 PMID:16459141 RGD:1581823 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lepr leptin receptor susceptibility ISO DNA:SNP:cds:p.Q223R(human) RGD PMID:27257426 RGD:21079462 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lipa lipase A, lysosomal acid type ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378988 PMID:34961328 PMID:35590109 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633
JBrowse link
G Lipc lipase C, hepatic type susceptibility
no_association
ISO associated with Diabetes Mellitus, Insulin-Dependent; DNA:transition:promoter:-480C>T (human)
DNA:SNP,haplotypes: (rs17269397)A>G (human)
RGD
GAD
PMID:11916946 PMID:33004870 PMID:15118671 PMID:12689525 PMID:15099346 RGD:2308839, RGD:329901841, RGD:1331525, RGD:1600664, RGD:1600663 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lipg lipase G, endothelial type ISO RGD PMID:16354105 RGD:1580865 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
JBrowse link
G Lmod1 leiomodin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28530674 NCBI chr13:46,754,048...46,796,186
Ensembl chr13:46,754,033...46,794,900
JBrowse link
G Lox lysyl oxidase IDA RGD PMID:12393934 RGD:1581886 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Lpl lipoprotein lipase ISO RGD PMID:8641022 RGD:1580537 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrp6 LDL receptor related protein 6 ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:28492532 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Lrp8 LDL receptor related protein 8 no_association
onset
ISO DNA:missense mutation:cds:p.R952Q (human) RGD PMID:18592168 PMID:17847002 RGD:2306125, RGD:2306124 NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352
JBrowse link
G Lta lymphotoxin alpha ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:15266304 PMID:15973460 RGD:1580414 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
JBrowse link
G Lum lumican ISO RGD PMID:11890723 RGD:1582121 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ISO associated with hypothyroidism;mRNA:decreased expression:venous blood (human) RGD PMID:32495070 RGD:155791451 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Mat2a methionine adenosyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
JBrowse link
G Mef2a myocyte enhancer factor 2a ISO RGD PMID:15811259 RGD:1580548 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Coronary artery disease
CTD
ClinVar
PMID:21378990 PMID:25741868 PMID:34961328 NCBI chr13:94,970,421...95,012,071
Ensembl chr13:94,970,424...95,011,972
JBrowse link
G Mir1 microRNA 1 disease_progression ISO miRNA:decreased expression:blood plasma (human) RGD PMID:25728840 RGD:11056497 NCBI chr18:1,887,537...1,887,623 JBrowse link
G Mir126a microRNA 126a disease_progression
severity
ISO miRNA:increased expression:blood plasma (human)
associated with Stable Angina,
RGD PMID:25728840 PMID:27497911 RGD:11056497, RGD:401850779 NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180
JBrowse link
G Mir133a1 microRNA 133a-1 ISO miRNA:decreased expression:blood plasma (human) RGD PMID:25728840 RGD:11056497 NCBI chr18:1,885,082...1,885,168 JBrowse link
G Mir145 microRNA 145 disease_progression ISO miRNA:decreased expression:artery wall (human) RGD PMID:25938589 RGD:11054026 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Mir146a microRNA 146a susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: (rs2910164) (human)
miRNA:increased expression:peripheral blood mononuclear cell, plasma
CTD
RGD
PMID:20524934 PMID:26909569 PMID:31866771 RGD:329337364, RGD:21081515 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Mir146b microRNA 146b ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:peripheral blood mononuclear cell, plasma RGD PMID:31866771 RGD:21081515 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir195 microRNA 195 ISO miRNA:decreased expression:blood plasma (human) RGD PMID:25728840 RGD:11056497 NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924
JBrowse link
G Mir208a microRNA 208a ISO miRNA:decreased expression:blood plasma (human) RGD PMID:25728840 RGD:11056497 NCBI chr15:28,425,570...28,425,652 JBrowse link
G Mir21 microRNA 21 ISO miRNA:increased expression:peripheral blood mononuclear cell, plasma
miRNA:increased expression:blood plasma (human)
RGD PMID:31866771 PMID:25728840 RGD:21081515, RGD:11056497 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir214 microRNA 214 ISO miRNA:increased expression:blood plasma (human) RGD PMID:25728840 RGD:11056497 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481
JBrowse link
G Mir223 microRNA 223 treatment ISO RGD PMID:25350775 RGD:11076984 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996
JBrowse link
G Mir30a microRNA 30a disease_progression ISO miRNA:increased expression:blood plasma (human) RGD PMID:25728840 RGD:11056497 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
JBrowse link
G Mir30e microRNA 30e ISO miRNA:increased expression:plasma, extracellular exosome (human) RGD PMID:30816508 RGD:401827150 NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323
JBrowse link
G Mir320a microRNA 320a disease_progression ISO miRNA:increased expression:blood plasma (human) RGD PMID:25728840 RGD:11056497 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
JBrowse link
G Mir423 microRNA 423 disease_progression ISO DNA:SNP: :rs6505162 (human)
miRNA:decreased expression:serum
RGD PMID:30289085 PMID:32404537 RGD:158014893, RGD:158014898 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
JBrowse link
G Mlxipl MLX interacting protein-like susceptibility ISO DNA:SNPs,haplotypes: (rs3812316) (human)
DNA:SNP:cds: G771C, Q241H (rs381231)
DNA:SNP:cds: C771G, H241Q
RGD PMID:21726544 PMID:19571538 PMID:25179879 RGD:401794579, RGD:401794582, RGD:401794581 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Mmp1 matrix metallopeptidase 1 severity ISO DNA:insertion, haplotype:promoter:g.-1607insG rs799750 (human) RGD PMID:15619398 PMID:17893005 RGD:1582527, RGD:7207049 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp12 matrix metallopeptidase 12 susceptibility ISO RGD PMID:10807873 RGD:1582366 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO DNA:insertion, haplotype:promoter:g.-1613insA rs3025058 (human)
CTD Direct Evidence: marker/mechanism
associated with Mucocutaneous Lymph Node Syndrome
CTD
RGD
PMID:8662692 PMID:17893005 PMID:16100452 RGD:7207049, RGD:8693322 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 susceptibility
treatment
ISO
IEP
RGD PMID:15191941 PMID:26261622 RGD:1582644, RGD:11344965 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mras muscle RAS oncogene homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:35590109 NCBI chr 8:99,944,036...100,006,771
Ensembl chr 8:99,944,036...99,996,408
JBrowse link
G Mrps6 mitochondrial ribosomal protein S6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:34961328 NCBI chr11:31,295,358...31,348,483
Ensembl chr11:31,295,614...31,348,484
JBrowse link
G Mthfr methylenetetrahydrofolate reductase no_association
susceptibility
ISO DNA:transition:cds:g.677C>T (human)
DNA:SNPs: (rs1801133, rs4846049) (Human)
RGD PMID:15648053 PMID:24315498 PMID:12387655 RGD:1580579, RGD:401850782, RGD:6893453 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mylip myosin regulatory light chain interacting protein ISO ClinVar Annotator: match by term: Coronary atherosclerosis ClinVar NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295
JBrowse link
G Mylk myosin light chain kinase susceptibility ISO associated with nicotine dependence; DNA:SNP: (rs16834817) RGD PMID:19706030 RGD:329970276 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase ISO RGD PMID:17283255 RGD:1642340 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Nat2 N-acetyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21572414 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Nbeal1 neurobeachin-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 9:61,575,154...61,743,896
Ensembl chr 9:61,575,356...61,736,750
JBrowse link
G Ngf nerve growth factor ISO RGD PMID:11935372 RGD:1580935 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Ngfr nerve growth factor receptor ISO RGD PMID:11935372 RGD:1580935 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nnmt nicotinamide N-methyltransferase severity ISO protein:increased expression:blood serum (human) RGD PMID:28174167 RGD:401793727 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO DNA:polymorphisms: :p.G908R, 3020_3021insC (human) RGD PMID:21565239 RGD:5508725 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Nos2 nitric oxide synthase 2 ISO associated with Mucocutaneous Lymph Node Syndrome; protein:increased expression:neutrophil, monocyte RGD PMID:14764920 RGD:1580941 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 susceptibility ISO DNA:duplication:intron:IVS4?-?+27 (human)
CTD Direct Evidence: marker/mechanism
DNA:snp:promoter:g.-786T>C (human)
DNA:snp:cds:c.894G>T (human)
CTD
RGD
PMID:10510054 PMID:14989558 PMID:17267746 PMID:19696404 PMID:8564837 More... RGD:7421529, RGD:7771578, RGD:7771567 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nppa natriuretic peptide A ISO DNA:snp:cds:c.2238T>C (human)
associated with Diabetes Mellitus, Type 2;DNA:SNP:exon: 2238T>C,rs5065 (human)
RGD PMID:12514664 PMID:22170009 RGD:1579982, RGD:7247716 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nppb natriuretic peptide B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18022110 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 ISO associated with type 2 diabetes mellitus;mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:28871240 RGD:401850555 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO DNA:missense mutation:cds:p.N363S (human) RGD PMID:12623935 RGD:1580790 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase susceptibility ISO DNA:SNP,haplotype: :p.S326C (rs1052133) (human) RGD PMID:23368530 RGD:401827273 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 severity ISO DNA:snp:3' utr:T>C (human)
DNA:missense mutation:cds:p.K167N (human)
RGD PMID:12810610 PMID:15562935 RGD:1580995, RGD:1580994 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Pappa pappalysin severity ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:11586954 PMID:16055491 RGD:1642327 NCBI chr 5:78,497,660...78,735,873
Ensembl chr 5:78,498,300...78,730,666
JBrowse link
G Parl presenilin associated, rhomboid-like susceptibility ISO DNA:missense mutation:cds:p.L262V (human) RGD PMID:18758826 RGD:12902623 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:27135400 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
G Pdgfd platelet derived growth factor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378988 PMID:34961328 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 no_association ISO DNA:missense mutations:cds:p.N536S, p.G670R (human)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:p.L125V (human)
DNA:polymorphism:5' utr:g.53G>A (human)
CTD
RGD
PMID:28530674 PMID:11795274 PMID:10780329 PMID:12732396 RGD:2311656, RGD:6771225, RGD:1581010 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Phactr1 phosphatase and actin regulator 1 susceptibility
sexual_dimorphism
ISO CTD Direct Evidence: marker/mechanism
DNA:hypermethylation, hypomethylation:promoter, exon: (human)
DNA:SNP:exon: (rs4714955) (human)
DNA:SNPs:intron: (rs9381439, rs9349379) (human)
associated with familial hypercholesterolemia;DNA:SNP:intron: (rs12526453) (human)
DNA:SNP:intron:g.12903957A>G (rs9349379) (human)
DNA:SNP:intron:g.12903725A>G (rs9349379) (human)
CTD
RGD
PMID:21378990 PMID:22751097 PMID:26098115 PMID:34961328 PMID:31499127 More... RGD:401901251, RGD:401901243, RGD:401900688, RGD:401900687, RGD:401900135, RGD:401851919 NCBI chr17:21,560,364...22,040,166
Ensembl chr17:21,562,721...22,039,831
JBrowse link
G Pik3c2g phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma ISO ClinVar Annotator: match by term: Premature coronary artery atherosclerosis ClinVar PMID:25741868 NCBI chr 4:172,483,752...172,851,623
Ensembl chr 4:172,484,345...172,850,544
JBrowse link
G Pla2g7 phospholipase A2 group VII disease_progression
susceptibility
ISO DNA:polymorphism: :p.A379V (human) RGD PMID:17070179 PMID:15115767 RGD:6482777, RGD:6482781 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
JBrowse link
G Plpp3 phospholipid phosphatase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 ISO associated with type 2 diabetes mellitus;DNA:SNP: :rs738409 (p.I148M) (human) RGD PMID:31377187 RGD:14981594 NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
JBrowse link
G Pon1 paraoxonase 1 susceptibility ISO DNA:missense mutation:cds:p.Q192R (human)
ClinVar Annotator: match by term: Coronary artery spasm 2, susceptibility to
CTD Direct Evidence: marker/mechanism|therapeutic
protein:increased activity:serum (human)
ClinVar
CTD
RGD
PMID:7916578 PMID:8098250 PMID:8675673 PMID:8770857 PMID:9215303 More... RGD:1580196, RGD:8547681, RGD:1580203 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Pon2 paraoxonase 2 severity ISO DNA:missense mutation:cds:p.C311S (human) RGD PMID:12454802 RGD:1580217 NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha susceptibility ISO DNA:snp:intron: (human) RGD PMID:16043164 RGD:1580228 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO protein:decreased expression:carotid artery, macrophage, smooth muscle cell (human) RGD PMID:21709632 RGD:8552814 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit ISO mRNA:decreased expression:blood (human) RGD PMID:30015926 RGD:401901084 NCBI chr 1:181,392,899...181,399,703
Ensembl chr 1:181,392,923...181,399,659
JBrowse link
G Prdm16 PR/SET domain 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35590109 NCBI chr 5:164,879,864...165,203,986
Ensembl chr 5:164,880,587...165,203,601
JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:25741868 PMID:28492532 NCBI chr 4:10,010,890...10,252,155
Ensembl chr 4:10,010,890...10,252,142
JBrowse link
G Procr protein C receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28530674 NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903
JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 2:196,022,361...196,026,874
Ensembl chr 2:196,022,361...196,026,874
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14642682 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pth parathyroid hormone ISO protein:increased expression:serum (human) RGD PMID:23460043 RGD:7242420 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 ISO DNA:SNP:exon 8:g.981C>T (human) RGD PMID:21676396 RGD:401965429 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 ISO DNA: snp: cds: rs2476601 RGD PMID:21846984 RGD:6484553 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D ISO DNA:SNP:intron: (rs10115782) (human) RGD PMID:22216278 RGD:401976461 NCBI chr 5:90,046,993...90,698,977
NCBI chr 5:91,122,354...91,641,754
Ensembl chr 5:90,048,966...92,369,396
JBrowse link
G Rbp4 retinol binding protein 4 sexual_dimorphism
susceptibility
severity
disease_progression
ISO protein:increased expression:blood plasma (human)
DNA:SNP:intron: (rs7094671) (human)
associated with hypothyroidism;protein:increased expression:blood serum (human)
protein:increased expression:epicardial fat (human)
RGD PMID:25437889 PMID:25479076 PMID:31278889 PMID:18854400 PMID:21645024 RGD:329845573, RGD:329845882, RGD:329845849, RGD:329845843, RGD:329845584 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
JBrowse link
G Ryr2 ryanodine receptor 2 ISO ClinVar Annotator: match by term: Premature coronary artery atherosclerosis ClinVar PMID:25741868 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G Sars1 seryl-tRNA synthetase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277
JBrowse link
G Sele selectin E susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:mutation: :p.S128R (human)
ClinVar Annotator: match by term: Coronary artery disease
ClinVar
RGD
PMID:25741868 PMID:17578587 RGD:2313596 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Selp selectin P ISO ClinVar Annotator: match by term: Premature coronary artery atherosclerosis ClinVar NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
JBrowse link
G Serpina1 serpin family A member 1 ISO protein:increased expression:serum RGD PMID:7832094 RGD:1643149 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
JBrowse link
G Serpine1 serpin family E member 1 susceptibility ISO DNA:insertion:promoter: (human) RGD PMID:9484978 RGD:1580190 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpinf2 serpin family F member 2 ISO RGD PMID:9184412 RGD:1625532 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
JBrowse link
G Sh2b3 SH2B adaptor protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr12:34,731,934...34,753,617
Ensembl chr12:34,731,911...34,753,616
JBrowse link
G Slc2a4 solute carrier family 2 member 4 ISO mRNA:decreased expression:epicardial fat, subcutaneous adipose tissue (human) RGD PMID:21645024 RGD:329845584 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc5a3 solute carrier family 5 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
JBrowse link
G Smad3 SMAD family member 3 ISO ClinVar Annotator: match by term: Coronary artery disease ClinVar PMID:25741868 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Soat2 sterol O-acyltransferase 2 susceptibility ISO DNA:polymorphisms: :p.E41G, p.T734I, IVS4-57_-58ins48bp (human) RGD PMID:16195894 RGD:1601112 NCBI chr 7:133,281,818...133,294,915
Ensembl chr 7:133,281,818...133,294,915
JBrowse link
G Sod1 superoxide dismutase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent RGD PMID:16338763 RGD:1600708 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:10811593 RGD:1580853 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sort1 sortilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 PMID:34961328 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO In type 2 diabetic patients RGD PMID:21034455 RGD:6903271 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 susceptibility
disease_progression
severity
ISO DNA:SNP, haplotype:: -36delG (human)
associated with type 2 diabetes mellitus; mRNA:increased expression:epicardial fat (human)
mRNA:decreased expression:blood serum (human)
RGD PMID:12752570 PMID:28367087 PMID:31610782 RGD:401827912, RGD:401842368, RGD:401842364 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 disease_progression ISO associated with type 2 diabetes mellitus;mRNA:increased expression:epicardial fat (human) RGD PMID:28367087 RGD:401842368 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member ISO GAD PMID:15118671 RGD:1331525 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
JBrowse link
G Tbx2 T-box transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35590109 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529
JBrowse link
G Tcf21 transcription factor 21 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: (rs12190287) (human)
CTD
RGD
PMID:21378990 PMID:22751097 PMID:26909569 RGD:329337364 NCBI chr 1:22,701,353...22,704,212
Ensembl chr 1:22,701,353...22,704,202
JBrowse link
G Tek TEK receptor tyrosine kinase ISO protein:increased expression:plasma RGD PMID:12814387 RGD:1601489 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804
JBrowse link
G Tert telomerase reverse transcriptase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16890917 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO GAD PMID:15118671 RGD:1331525 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Thbd thrombomodulin severity ISO RGD PMID:17012137 RGD:1601638 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
JBrowse link
G Tll1 tolloid-like 1 severity ISO associated with type 2 diabetes:DNA:SNP:CDS:rs1503298 (human) RGD PMID:21911782 RGD:155883159 NCBI chr16:25,509,146...25,710,330
Ensembl chr16:25,509,146...25,709,543
JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20524934 PMID:15632890 RGD:1580736 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:15059615 RGD:1626412 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO protein:increased expression:serum RGD PMID:15926884 RGD:1620893 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A severity ISO RGD PMID:19845893 RGD:5131425 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnni3 troponin I3, cardiac type ISO RGD PMID:12221049 RGD:1580780 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580
JBrowse link
G Tp53 tumor protein p53 ISO DNA:misssense mutation: :p.R72P (rs1042522) (human) RGD PMID:29482350 RGD:14995930 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Traf6 TNF receptor associated factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20524934 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Trib1 tribbles pseudokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24097064 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731
JBrowse link
G Ttn titin ISO RGD PMID:12221049 RGD:1580780 NCBI chr 3:61,652,432...61,924,912
Ensembl chr 3:61,652,439...61,924,741
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
JBrowse link
G Vamp5 vesicle-associated membrane protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 4:104,423,813...104,435,059
Ensembl chr 4:104,423,820...104,426,212
JBrowse link
G Vamp8 vesicle-associated membrane protein 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34961328 NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897
JBrowse link
G Vdr vitamin D receptor severity ISO DNA:SNP (human) RGD PMID:9761785 RGD:4889864 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:14668888 PMID:15937083 PMID:15754021 RGD:1580569 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vim vimentin ISO protein:increased expression:monocyte RGD PMID:21938407 RGD:6480617 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vtn vitronectin ISO RGD PMID:15678274 RGD:1580816 NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810
JBrowse link
G Wdr12 WD repeat domain 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 9:61,475,498...61,502,762
Ensembl chr 9:61,475,517...61,502,469
JBrowse link
G Wrn WRN RecQ like helicase ISO RGD PMID:11186893 RGD:1580824 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 onset ISO DNA:polymorphism:: (rs1799782) (human) RGD PMID:24315498 RGD:401850782 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 susceptibility ISO DNA:SNP,haplotypes:exon 7: p.T241M (rs861539) (Human) RGD PMID:23368530 RGD:401827273 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444
JBrowse link
G Zc3hc1 zinc finger, C3HC-type containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21378990 NCBI chr 4:58,989,989...59,011,925
Ensembl chr 4:58,989,987...59,011,933
JBrowse link
G Zfyve21 zinc finger FYVE-type containing 21 ISO ClinVar Annotator: match by term: Premature coronary artery atherosclerosis ClinVar PMID:25741868 NCBI chr 6:130,873,979...130,894,618
Ensembl chr 6:130,873,912...130,894,411
JBrowse link
G Zhx3 zinc fingers and homeoboxes 3 ISO ClinVar Annotator: match by term: Coronary atherosclerosis ClinVar PMID:25741868 PMID:28492532 NCBI chr 3:149,417,787...149,548,671
Ensembl chr 3:149,417,818...149,527,079
JBrowse link
Coronary Artery Disease, Autosomal Dominant 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2a myocyte enhancer factor 2a ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Coronary artery disease, autosomal dominant, 1 | ClinVar Annotator: match by term: Coronary artery disease/myocardial infarction
OMIM
CTD
ClinVar
PMID:14645853 PMID:15496429 PMID:15841183 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
JBrowse link
Coronary Artery Disease, Autosomal Dominant 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Coronary artery disease, autosomal dominant 2
OMIM
CTD
ClinVar
PMID:17332414 PMID:23703864 PMID:25741868 PMID:28492532 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
Coronary Artery Disease, Development of, in HIV term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 ISO ClinVar Annotator: match by term: Coronary artery disease, development of, in HIV ClinVar PMID:11500196 PMID:15466648 PMID:16352737 PMID:16596675 PMID:18940815 More... NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
coronary artery vasospasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap9 Rho GTPase activating protein 9 ISO ClinVar Annotator: match by term: Coronary artery spasm 3, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:19911011 NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524
JBrowse link
G Nos3 nitric oxide synthase 3 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Coronary artery spasm 1, susceptibility to
CTD
ClinVar
PMID:9737779 PMID:9894802 PMID:10359729 PMID:10475066 PMID:10510054 More... NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11810302 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
Coronary Disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO ClinVar Annotator: match by term: Early-onset coronary artery disease ClinVar NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Early-onset coronary artery disease
CTD
ClinVar
PMID:19060911 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 ISO ClinVar Annotator: match by term: Early-onset coronary artery disease ClinVar NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
G Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar NCBI chr 3:10,162,087...10,182,835
Ensembl chr 3:10,162,096...10,191,423
JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:deletion:intron:IVS16+1464-1751del (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:8170965 PMID:9488209 RGD:8142364 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ace2 angiotensin converting enzyme 2 susceptibility ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :8790G>A (human) RGD PMID:18753062 RGD:2313798 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Ada adenosine deaminase ISO protein:increased expression:leukocyte RGD PMID:17259686 RGD:1624286 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 ISO protein:decreased activity:plasma (human)
ClinVar Annotator: match by term: Three Vessel Coronary Disease
ClinVar
RGD
PMID:25741868 PMID:28492532 PMID:12670342 RGD:10449044 NCBI chr 3:10,299,264...10,338,464
Ensembl chr 3:10,300,028...10,346,687
JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar NCBI chr 8:90,704,727...90,744,333
Ensembl chr 8:90,704,727...90,744,328
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing disease_progression ISO associated with Diabetes mellitus, Type2; RGD PMID:22207678 PMID:22019747 RGD:5686379, RGD:5686406 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adrb2 adrenoceptor beta 2 susceptibility ISO DNA:polymorphism: :p.Q27E RGD PMID:12682000 RGD:1601128 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Adrb3 adrenoceptor beta 3 susceptibility ISO associated with Diabetes Mellitus, Type 2; DNA:missense mutation:cds:p.W64R rs4994(human) RGD
GAD
PMID:10421225 PMID:20536507 PMID:15118671 RGD:1559326, RGD:5684776, RGD:1331525 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Ager advanced glycosylation end product-specific receptor susceptibility ISO protein:decreased expression:plasma (human)
associated with Heart Failure; protein:increased expression:plasma (human)
RGD PMID:23396398 PMID:20685687 RGD:7243186, RGD:7244134 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Agtr1a angiotensin II receptor, type 1a susceptibility
no_association
ISO DNA:polymorphism:3' utr:1166A>C
DNA:polymorphism:3' utr:1166A>C (human)
RGD PMID:9456365 PMID:9857918 RGD:1601152, RGD:1566499 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 ISO DNA:missense mutation:cds:V140I (rs37369)(human) RGD PMID:24834905 RGD:329961320 NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926
JBrowse link
G Apoa4 apolipoprotein A4 susceptibility
no_association
ISO DNA:missense mutation:cds:p.T347S (human) RGD PMID:12676816 PMID:9013087 RGD:1578411, RGD:5685683 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apob apolipoprotein B ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Early-onset coronary artery disease
CTD
ClinVar
PMID:17658632 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoc2 apolipoprotein C2 susceptibility ISO RGD PMID:7590197 RGD:1601205 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
JBrowse link
G Apoc3 apolipoprotein C3 no_association
susceptibility
ISO DNA:polymorphism:promoter:-482C>T
ClinVar Annotator: match by term: Coronary heart disease
associated with Diabetes Mellitus, Non-Insulin-Dependent
ClinVar
RGD
PMID:11060345 PMID:19074352 PMID:20097930 PMID:23701270 PMID:24941081 More... RGD:1601224, RGD:2306754 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Apoe apolipoprotein E onset ISO DNA:polymorphisms, haplotype:promoter, cds:g.-219G>T, p.C112R, p.R158C (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:10736278 PMID:11862316 PMID:11862316 RGD:1578479, RGD:1578479 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Ccdc92 coiled-coil domain containing 92 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr12:31,796,102...31,823,333
Ensembl chr12:31,796,684...31,823,337
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 resistance ISO DNA:polymorphisms:multiple (human) RGD PMID:16055130 RGD:1581176 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cd14 CD14 molecule ISO protein:increased expression:monocyte RGD PMID:10831941 RGD:2314175 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd36 CD36 molecule ISO mRNA:increased expression:monocyte
ClinVar Annotator: match by term: CORONARY HEART DISEASE, SUSCEPTIBILITY TO, 7
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
RGD
PMID:25741868 PMID:28960434 PMID:33116287 PMID:18067591 RGD:6893507 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd40lg CD40 ligand treatment IDA RGD PMID:23819214 RGD:7248750 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO DNA:polymorphism: :p.V249I (human)
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Coronary heart disease, susceptibility to, 1
CTD
OMIM
ClinVar
RGD
PMID:25741868 PMID:11532900 RGD:4891901 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Cyba cytochrome b-245 alpha chain ISO RGD PMID:10488959 RGD:1580275 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 resistance ISO DNA:polymorphism:promoter:-50G>T (human) RGD PMID:17429317 RGD:1625377 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Dab2ip DAB2 interacting protein ISO DNA:SNP:CDS:rs7025486 (human) RGD PMID:21444365 RGD:401938618 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Dnah11 dynein, axonemal, heavy chain 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19060911 NCBI chr 6:138,839,175...139,155,554
Ensembl chr 6:138,839,177...139,155,536
JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:16595607 RGD:1580981 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Esr2 estrogen receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17367797 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G F12 coagulation factor XII ISO protein:decreased activity:: RGD PMID:18021303 RGD:11041785 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G F13a1 coagulation factor XIII A1 chain ISO RGD PMID:11391716 RGD:1581030 NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO associated with Diabetes Mellitus RGD PMID:15451784 RGD:2315870 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO mRNA, protein:increased expression:ventricle myocardium RGD PMID:16139132 RGD:2313728 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase ISO DNA:SNP: :rs9939609 (human) RGD PMID:26555680 RGD:11555922 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased activity:serum RGD PMID:16772340 RGD:2315604 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Glul glutamate-ammonia ligase ISO associated with type 2 diabetes mellitus;DNA:SNP: :rs10911021 (human) RGD PMID:23982368 RGD:401794410 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha ISO RGD PMID:14592833 RGD:1580433 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
JBrowse link
G Gp6 glycoprotein VI treatment
exacerbates
ISO protein:increased expression:venous blood, platelet (human)
DNA:hypomethylation:promoter
RGD PMID:17105818 PMID:20049463 PMID:31783053 RGD:401794440, RGD:401824649, RGD:401824645 NCBI chr 1:69,429,232...69,492,709
Ensembl chr 1:69,465,789...69,491,326
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase disease_progression ISO RGD PMID:15809366 RGD:5508474 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:15869055 RGD:1598404 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf1a HNF1 homeobox A ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hp haptoglobin severity ISO RGD PMID:16673012 RGD:1626344 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO DNA:SNPs: : -110A>C (rs1008438), 190G>C (rs1043618) (human) RGD PMID:19333379 RGD:7257652 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO RGD PMID:12059985 RGD:1624217 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Igf1 insulin-like growth factor 1 ISO RGD PMID:15521962 RGD:1626121 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit ISO RGD PMID:15521962 RGD:1626121 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO RGD PMID:15521962 RGD:1626121 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 ISO RGD PMID:15521962 RGD:1626121 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Il18 interleukin 18 ISO ClinVar Annotator: match by term: Three Vessel Coronary Disease ClinVar NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1b interleukin 1 beta ISO DNA:polymorphism RGD PMID:15379752 RGD:1626636 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Irf8 interferon regulatory factor 8 susceptibility ISO DNA:SNPs:intron 4, intron 2: (rs925994,rs10514610) (human) RGD PMID:23661672 RGD:329902076 NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829
JBrowse link
G Irs1 insulin receptor substrate 1 ISO ClinVar Annotator: match by term: Coronary artery disease, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:1311924 PMID:7623569 PMID:8104271 PMID:8647950 PMID:10084586 More... NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Itga2 integrin subunit alpha 2 no_association ISO RGD PMID:9684730 RGD:1582306 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Itgam integrin subunit alpha M exacerbates ISO protein:increased expression:monocyte (human) RGD PMID:20876457 RGD:329901842 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgb3 integrin subunit beta 3 ISO DNA:polymorphism:exon RGD PMID:10583927 RGD:5128478 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Kalrn kalirin, RhoGEF kinase ISO ClinVar Annotator: match by term: Coronary heart disease, susceptibility to, 5 ClinVar PMID:17357071 PMID:25741868 NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610
JBrowse link
G Kat2b lysine acetyltransferase 2B severity ISO DNA:snp:promoter:g.-2481G>C (human) RGD PMID:21062767 RGD:9590309 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 no_association ISO RGD PMID:12964027 RGD:1581699 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
JBrowse link
G Kdr kinase insert domain receptor ISO mRNA, protein:increased expression:ventricle myocardium RGD PMID:16139132 RGD:2313728 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Ldlr low density lipoprotein receptor ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Early-onset coronary artery disease
CTD
ClinVar
PMID:9430375 PMID:9712531 PMID:10422804 PMID:11810272 PMID:11845603 More... NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lepr leptin receptor onset ISO DNA:SNP: C>T (rs6656451) (human) RGD PMID:29848931 RGD:401799677 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lgals2 galectin 2 susceptibility ISO RGD PMID:17040205 RGD:1581853 NCBI chr 7:110,403,171...110,410,046
Ensembl chr 7:110,403,173...110,404,802
JBrowse link
G Lipc lipase C, hepatic type susceptibility ISO associated with Obesity and Diabetes; DNA:transition:promoter:-514C>T (human) RGD PMID:16570154 RGD:2308824 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lpl lipoprotein lipase IEP
ISO
ClinVar Annotator: match by term: Coronary heart disease ClinVar
RGD
PMID:8199176 PMID:8541837 PMID:8872057 PMID:10364086 PMID:10517255 More... RGD:13794381 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrp1 LDL receptor related protein 1 susceptibility ISO RGD PMID:15121769 RGD:1581911 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Maco1 macoilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19060911 NCBI chr 5:147,012,416...147,075,265
Ensembl chr 5:147,012,867...147,075,001
JBrowse link
G Mb myoglobin severity ISO RGD PMID:15976963 RGD:1582388 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
JBrowse link
G Mgp matrix Gla protein susceptibility ISO RGD PMID:16973975 RGD:1582502 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
JBrowse link
G Mif macrophage migration inhibitory factor IEP coronary occlusion; mRNA:increased expression:myocardium RGD PMID:20367970 RGD:4890973 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mlxip MLX interacting protein susceptibility ISO DNA:SNP:3'utr: (rs4758685) (human) RGD PMID:23840567 RGD:401794443 NCBI chr12:33,128,524...33,192,300
Ensembl chr12:33,128,520...33,192,374
JBrowse link
G Mlxipl MLX interacting protein-like susceptibility ISO DNA:SNP: (rs35493868); in younger than 55 years of age RGD PMID:29848931 RGD:401799677 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Mmp1 matrix metallopeptidase 1 susceptibility ISO DNA:insertion:promoter:g.-1607insG (human) RGD PMID:14499230 RGD:1582537 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp3 matrix metallopeptidase 3 susceptibility ISO ClinVar Annotator: match by term: Coronary heart disease, susceptibility to, 6
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:7727178 PMID:8662692 PMID:9699891 PMID:10190398 PMID:10351963 More... NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mras muscle RAS oncogene homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:28869590 NCBI chr 8:99,944,036...100,006,771
Ensembl chr 8:99,944,036...99,996,408
JBrowse link
G Mthfr methylenetetrahydrofolate reductase