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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Somatic Colonic Adenocarcinoma
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Accession:DOID:9006678 term browser browse the term
Definition:An adenocarcinoma arising from the colon, caused by a somatic mutation. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma.
Synonyms:primary_id: RDO:9000696


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colon signet ring adenocarcinoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RUNX1 RUNX family transcription factor 1 IEP mRNA:increased expression:colon RGD PMID:29747153 RGD:126779566 NCBI chr21:34,787,801...35,049,302
Ensembl chr21:34,787,801...36,004,667 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 151016
    disease of cellular proliferation 29434
      cancer 24086
        cell type cancer 16299
          carcinoma 12091
            colon carcinoma 228
              colon adenocarcinoma 65
                Somatic Colonic Adenocarcinoma 1
                  colon signet ring adenocarcinoma 1
Path 2
Term Annotations click to browse term
  disease 151016
    disease of anatomical entity 138079
      gastrointestinal system disease 21263
        Digestive System Neoplasms 5383
          Gastrointestinal Neoplasms 5004
            gastrointestinal system cancer 3902
              intestinal cancer 1247
                large intestine cancer 1245
                  colorectal cancer 1245
                    colorectal carcinoma 202
                      colorectal adenocarcinoma 141
                        colon adenocarcinoma 65
                          Somatic Colonic Adenocarcinoma 1
                            colon signet ring adenocarcinoma 1
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