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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Somatic Colonic Adenocarcinoma
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Accession:DOID:9006678 term browser browse the term
Definition:An adenocarcinoma arising from the colon, caused by a somatic mutation. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma.
Synonyms:primary_id: RDO:9000696


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colon signet ring adenocarcinoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RUNX1 RUNX family transcription factor 1 ISO mRNA:increased expression:colon RGD PMID:29747153 RGD:126779566 NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15760
    disease of cellular proliferation 7491
      cancer 5506
        cell type cancer 3669
          carcinoma 3171
            colon carcinoma 133
              colon adenocarcinoma 63
                Somatic Colonic Adenocarcinoma 1
                  colon signet ring adenocarcinoma 1
Path 2
Term Annotations click to browse term
  disease 15760
    disease of anatomical entity 15380
      gastrointestinal system disease 6645
        Digestive System Neoplasms 3727
          Gastrointestinal Neoplasms 3614
            gastrointestinal system cancer 2847
              intestinal cancer 994
                large intestine cancer 993
                  colorectal cancer 993
                    colorectal carcinoma 167
                      colorectal adenocarcinoma 119
                        colon adenocarcinoma 63
                          Somatic Colonic Adenocarcinoma 1
                            colon signet ring adenocarcinoma 1
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