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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Somatic Colonic Adenocarcinoma
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Accession:DOID:9006678 term browser browse the term
Definition:An adenocarcinoma arising from the colon, caused by a somatic mutation. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma.
Synonyms:primary_id: RDO:9000696


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colon signet ring adenocarcinoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Runx1 RUNX family transcription factor 1 ISO mRNA:increased expression:colon RGD PMID:29747153 RGD:126779566 NCBI chr11:45,325,778...45,560,300
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19134
    disease of cellular proliferation 7891
      cancer 5722
        cell type cancer 3783
          carcinoma 3273
            colon carcinoma 137
              colon adenocarcinoma 65
                Somatic Colonic Adenocarcinoma 1
                  colon signet ring adenocarcinoma 1
Path 2
Term Annotations click to browse term
  disease 19134
    disease of anatomical entity 18447
      gastrointestinal system disease 7194
        Digestive System Neoplasms 3852
          Gastrointestinal Neoplasms 3729
            gastrointestinal system cancer 2919
              intestinal cancer 1014
                large intestine cancer 1013
                  colorectal cancer 1013
                    colorectal carcinoma 172
                      colorectal adenocarcinoma 124
                        colon adenocarcinoma 65
                          Somatic Colonic Adenocarcinoma 1
                            colon signet ring adenocarcinoma 1
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