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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Nonpenetrating Wounds
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Accession:DOID:9006659 term browser browse the term
Definition:Injuries caused by impact with a blunt object where there is no penetration of the skin.
Synonyms:exact_synonym: Blunt Injuries;   Blunt Injury;   Nonpenetrating Injuries;   Nonpenetrating Injury;   Nonpenetrating Wound
 primary_id: MESH:D014949


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Brain Concussion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 IEP RGD PMID:26448536 RGD:13506960 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 IEP RGD PMID:26448536 RGD:13506960 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd4 dopamine receptor D4 IEP RGD PMID:26448536 RGD:13506960 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Il6 interleukin 6 treatment IDA RGD PMID:27113205 RGD:11062140 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
Brain Contusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 ameliorates IMP RGD PMID:31654641 RGD:408418727 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:28140659 RGD:13782305 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 treatment IEP RGD PMID:28140659 RGD:13782305 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Il1b interleukin 1 beta treatment IEP RGD PMID:31654641 RGD:408418727 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Pycard PYD and CARD domain containing treatment IMP RGD PMID:19401709 RGD:5491174 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Tnf tumor necrosis factor treatment IEP RGD PMID:31654641 RGD:408418727 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Closed Head Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 ISO protein:increased expression:neuron RGD PMID:16004578 RGD:6483315 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Gfap glial fibrillary acidic protein IEP RGD PMID:8833197 RGD:6480531 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 ISO human protein in a rat model RGD PMID:17014847 RGD:13504858 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO protein:decreased expression:serum: RGD PMID:12002507 RGD:8548865 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO protein:decreased expression:serum: RGD PMID:12002507 RGD:8548865 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Vim vimentin IEP RGD PMID:8833197 RGD:6480531 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
Contusions term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 IEP protein:increased expression:serum RGD PMID:16832247 RGD:2307147 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ctsb cathepsin B IEP mRNA, protein:increased expression, increased activity:gastrocnemius (rat) RGD PMID:11788364 RGD:631244 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsh cathepsin H IEP mRNA:increased expression:gastrocnemius (rat) RGD PMID:11788364 RGD:631244 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824 		JBrowse link
G Ctsl cathepsin L IEP mRNA, protein:increased expression, increased activity:gastrocnemius (rat) RGD PMID:11788364 RGD:631244 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Dbh dopamine beta-hydroxylase IEP mRNA:increased expression:adrenal gland (rat) RGD PMID:18987458 RGD:5129532 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G F2 coagulation factor II, thrombin IEP associated with Spinal Cord Injuries;mRNA:increased expression:spinal cord RGD PMID:11186232 RGD:7387307 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase IEP mRNA:increased expression:adrenal gland (rat) RGD PMID:18987458 RGD:5129532 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
G Slc38a2 solute carrier family 38, member 2 IEP RGD PMID:24045877 RGD:9999219 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436 		JBrowse link
G Th tyrosine hydroxylase IEP mRNA:increased expression:adrenal gland (rat) RGD PMID:18987458 RGD:5129532 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
Pulmonary Contusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 IEP protein:increased expression:alveolar system (rat) RGD PMID:16044083 RGD:11060268 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Il6 interleukin 6 IEP protein:increased expression:bronchoalveolar lavage fluid (rat) RGD PMID:16044083 RGD:11060268 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19137
    Wounds and Injuries 994
      Nonpenetrating Wounds 25
        Closed Head Injuries + 10
        Contusions + 16
paths to the root