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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Eye Injuries
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Accession:DOID:9006447 term browser browse the term
Definition:Damage or trauma inflicted to the eye by external means. The concept includes both surface injuries and intraocular injuries.
Synonyms:exact_synonym: Eye Injury
 primary_id: MESH:D005131;   RDO:0005555
 xref: EFO:0009485

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Eye Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pparg peroxisome proliferator activated receptor gamma treatment ISO RGD PMID:18658087 RGD:8552893 NCBI chrNW_004936602:1,230,907...1,368,588
Ensembl chrNW_004936602:1,230,907...1,304,743 		JBrowse link
Corneal Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh3a1 aldehyde dehydrogenase 3 family member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28038895 NCBI chrNW_004936881:71,047...77,543
Ensembl chrNW_004936881:70,951...77,839 		JBrowse link
G Tp63 tumor protein p63 ISO RGD PMID:12167247 RGD:11568649 NCBI chrNW_004936578:492,267...705,282
Ensembl chrNW_004936578:491,507...705,729 		JBrowse link
Corneal Perforation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma ISO mRNA,protein:increased expression:corneal RGD PMID:15832292 RGD:8157597 NCBI chrNW_004936545:6,139,130...6,144,543
Ensembl chrNW_004936545:6,139,116...6,148,452 		JBrowse link
Eye Burns term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 treatment ISO RGD PMID:22553604 RGD:7364851 NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502 		JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:retina RGD PMID:9618720 RGD:7794723 NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO protein:increased expression:cornea, neutrophil, macrophage (rat) RGD PMID:24194635 RGD:8552904 NCBI chrNW_004936602:1,230,907...1,368,588
Ensembl chrNW_004936602:1,230,907...1,304,743 		JBrowse link
Penetrating Eye Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neo1 neogenin 1 ISO protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chrNW_004936471:32,345,578...32,517,245
Ensembl chrNW_004936471:32,292,745...32,516,624 		JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a ISO protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chrNW_004936483:9,753,112...9,792,817
Ensembl chrNW_004936483:9,766,275...9,793,001 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14637
    sensory system disease 6687
      eye disease 3441
        Eye Injuries 8
          Anterior Capsular Rupture, Ocular 0
          Corneal Injuries + 3
          Eye Burns 3
          Eye Foreign Bodies 0
          Penetrating Eye Injuries 2
          Posterior Capsular Rupture, Ocular 0
Path 2
Term Annotations click to browse term
  disease 14637
    disease of anatomical entity 14326
      nervous system disease 12610
        Neurologic Manifestations 9424
          sensory system disease 6687
            eye disease 3441
              Eye Injuries 8
                Anterior Capsular Rupture, Ocular 0
                Corneal Injuries + 3
                Eye Burns 3
                Eye Foreign Bodies 0
                Penetrating Eye Injuries 2
                Posterior Capsular Rupture, Ocular 0
paths to the root