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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Eye Injuries
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Accession:DOID:9006447 term browser browse the term
Definition:Damage or trauma inflicted to the eye by external means. The concept includes both surface injuries and intraocular injuries.
Synonyms:exact_synonym: Eye Injury
 primary_id: MESH:D005131;   RDO:0005555
 xref: EFO:0009485


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show annotations for term's descendants           Sort by:
Eye Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 ISO protein:increased expression:lens RGD PMID:15273655 RGD:8655664 NCBI chrNW_004624777:3,268,674...3,321,424
Ensembl chrNW_004624777:3,268,953...3,321,145
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma treatment ISO RGD PMID:18658087 RGD:8552893 NCBI chrNW_004624956:84,673...207,176
Ensembl chrNW_004624956:83,842...149,481
JBrowse link
Corneal Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp63 tumor protein p63 ISO RGD PMID:12167247 RGD:11568649 NCBI chrNW_004624730:67,283,444...67,489,808
Ensembl chrNW_004624730:67,286,160...67,489,670
JBrowse link
Corneal Perforation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma ISO mRNA,protein:increased expression:corneal RGD PMID:15832292 RGD:8157597 NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534
JBrowse link
Eye Burns term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 treatment ISO RGD PMID:22553604 RGD:7364851 NCBI chrNW_004624807:4,687,249...4,691,658
Ensembl chrNW_004624807:4,687,176...4,691,732
JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:retina RGD PMID:9618720 RGD:7794723 NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO protein:increased expression:cornea, neutrophil, macrophage (rat) RGD PMID:24194635 RGD:8552904 NCBI chrNW_004624956:84,673...207,176
Ensembl chrNW_004624956:83,842...149,481
JBrowse link
Penetrating Eye Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 ISO mRNA:increased expression:retina RGD PMID:9268592 RGD:8655567 NCBI chrNW_004624777:3,268,674...3,321,424
Ensembl chrNW_004624777:3,268,953...3,321,145
JBrowse link
G Neo1 neogenin 1 ISO protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chrNW_004624781:1,021,460...1,227,680
Ensembl chrNW_004624781:1,019,603...1,227,666
JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a ISO protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chrNW_004624768:10,739,674...10,778,036
Ensembl chrNW_004624768:10,751,991...10,778,050
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14229
    sensory system disease 6534
      eye disease 3370
        Eye Injuries 8
          Anterior Capsular Rupture, Ocular 0
          Corneal Injuries + 2
          Eye Burns 3
          Eye Foreign Bodies 0
          Penetrating Eye Injuries 3
          Posterior Capsular Rupture, Ocular 0
Path 2
Term Annotations click to browse term
  disease 14229
    disease of anatomical entity 13931
      nervous system disease 12269
        Neurologic Manifestations 9168
          sensory system disease 6534
            eye disease 3370
              Eye Injuries 8
                Anterior Capsular Rupture, Ocular 0
                Corneal Injuries + 2
                Eye Burns 3
                Eye Foreign Bodies 0
                Penetrating Eye Injuries 3
                Posterior Capsular Rupture, Ocular 0
paths to the root