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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Eye Injuries
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Accession:DOID:9006447 term browser browse the term
Definition:Damage or trauma inflicted to the eye by external means. The concept includes both surface injuries and intraocular injuries.
Synonyms:exact_synonym: Eye Injury
 primary_id: MESH:D005131;   RDO:0005555
 xref: EFO:0009485


show annotations for term's descendants           Sort by:
Eye Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF2 fibroblast growth factor 2 ISO protein:increased expression:lens RGD PMID:15273655 RGD:8655664 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151 		JBrowse link
G MIR183 microRNA mir-183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27208084 NCBI chr14:7,068,542...7,068,603
Ensembl chr14:7,068,519...7,068,625 		JBrowse link
G MIR96 microRNA mir-96 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27208084 NCBI chr14:7,068,754...7,068,842
Ensembl chr14:7,068,754...7,068,842 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma treatment ISO RGD PMID:18658087 RGD:8552893 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
Corneal Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28038895 NCBI chr 5:40,466,237...40,474,272
Ensembl chr 5:40,466,237...40,474,457 		JBrowse link
G TP63 tumor protein p63 ISO RGD PMID:12167247 RGD:11568649 NCBI chr34:21,766,861...21,985,095
Ensembl chr34:21,766,496...21,983,046 		JBrowse link
Corneal Perforation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma ISO mRNA,protein:increased expression:corneal RGD PMID:15832292 RGD:8157597 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
Eye Burns term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 treatment ISO RGD PMID:22553604 RGD:7364851 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057 		JBrowse link
G IL1B interleukin 1 beta ISO protein:increased expression:retina RGD PMID:9618720 RGD:7794723 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO protein:increased expression:cornea, neutrophil, macrophage (rat) RGD PMID:24194635 RGD:8552904 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
Penetrating Eye Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF2 fibroblast growth factor 2 ISO mRNA:increased expression:retina RGD PMID:9268592 RGD:8655567 NCBI chr19:17,403,288...17,463,143
Ensembl chr19:16,994,661...17,463,151 		JBrowse link
G NEO1 neogenin 1 ISO protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chr30:36,387,425...36,622,491
Ensembl chr30:36,387,259...36,622,154 		JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a ISO protein:increased expression:retina RGD PMID:21887516 RGD:9850142 NCBI chr 3:47,044,342...47,089,923
Ensembl chr 3:47,061,910...47,089,294 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15754
    sensory system disease 7033
      eye disease 3621
        Eye Injuries 11
          Anterior Capsular Rupture, Ocular 0
          Corneal Injuries + 3
          Eye Burns 3
          Eye Foreign Bodies 0
          Penetrating Eye Injuries 3
          Posterior Capsular Rupture, Ocular 0
Path 2
Term Annotations click to browse term
  disease 15754
    disease of anatomical entity 15375
      nervous system disease 13502
        Neurologic Manifestations 9990
          sensory system disease 7033
            eye disease 3621
              Eye Injuries 11
                Anterior Capsular Rupture, Ocular 0
                Corneal Injuries + 3
                Eye Burns 3
                Eye Foreign Bodies 0
                Penetrating Eye Injuries 3
                Posterior Capsular Rupture, Ocular 0
paths to the root