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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Peritoneal Diseases
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Accession:DOID:9006175 term browser browse the term
Definition:Pathological processes involving the PERITONEUM.
Synonyms:exact_synonym: Peritoneal Disease;   disease of peritoneum
 primary_id: MESH:D010532
 xref: EFO:0009541



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Peritoneal Diseases term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir17 microRNA 17 ISO associated with end stage renal failure RGD PMID:30598338 RGD:25823143 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Notch1 notch receptor 1 IMP mRNA:increased expression: : RGD PMID:20056840 RGD:2325288 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
Mesenteric Ischemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2 coagulation factor II, thrombin ISO CTD Direct Evidence: marker/mechanism CTD PMID:24282370 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F5 coagulation factor V ISO CTD Direct Evidence: marker/mechanism CTD PMID:24282370 NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta ISO RGD PMID:17095718 RGD:11040529 NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392
JBrowse link
G Pf4 platelet factor 4 ameliorates ISO RGD PMID:23568488 RGD:329901761 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
JBrowse link
mesenteric vascular occlusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Icam1 intercellular adhesion molecule 1 treatment IMP RGD PMID:7858885 RGD:11522711 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Jak2 Janus kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20434300 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Serpind1 serpin family D member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:1831893 NCBI chr11:83,664,517...83,675,593
Ensembl chr11:83,664,518...83,675,519
JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ameliorates IDA RGD PMID:18091551 RGD:127284848 NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203
JBrowse link
peritoneal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 ISO ClinVar Annotator: match by term: Primary peritoneal carcinoma ClinVar PMID:25741868 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
Peritoneal Fibrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme treatment IMP
ISO
RGD PMID:15770604 PMID:19270231 RGD:12879430, RGD:12879821 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ager advanced glycosylation end product-specific receptor treatment IDA associated with Diabetic Nephropathies RGD PMID:19759273 RGD:7244162 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment ISO RGD PMID:23032084 RGD:14995948 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Dnmt1 DNA methyltransferase 1 IEP protein:increased expression:peritoneum: RGD PMID:25256793 RGD:9588609 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 treatment IMP RGD PMID:31836774 RGD:32733624 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G F10 coagulation factor X IEP RGD PMID:19458308 RGD:7394780 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
JBrowse link
G F3 coagulation factor III, tissue factor IEP RGD PMID:19458308 RGD:7394780 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G F5 coagulation factor V IEP RGD PMID:19458308 RGD:7394780 NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G Fgf10 fibroblast growth factor 10 treatment ISO miR-145 inhibitor
mRNA:decreased expression:peritoneum (mouse)
RGD PMID:31431501 PMID:31431501 RGD:126928131, RGD:126928131 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866
JBrowse link
G Mir21 microRNA 21 IEP RNA:increased expression:peritoneal fluid,tissue RGD PMID:30515805 RGD:40925948 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:22101032 RGD:6771356 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Serpinc1 serpin family C member 1 treatment ISO associated with Peritonitis RGD PMID:18458955 RGD:11035266 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
JBrowse link
G Serpine1 serpin family E member 1 ISO protein:increased expression:peritoneal fluid: RGD PMID:25530106 RGD:13208550 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpinh1 serpin family H member 1 disease_progression
treatment
IEP
ISO
IMP
protein:increased expression:peritoneum (rat) RGD PMID:12691502 PMID:32585450 PMID:15458466 PMID:12911538 RGD:41410779, RGD:41410783, RGD:41410782, RGD:41410781 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 IEP mRNA, protein:decreased expression:peritoneal fluid,tissue RGD PMID:30515805 RGD:40925948 NCBI chr 2:120,557,256...120,561,917
Ensembl chr 2:120,556,706...120,566,189
JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:17199790 PMID:28190234 RGD:14985233 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 treatment IMP RGD PMID:22912904 RGD:7777188 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
JBrowse link
G Xbp1 X-box binding protein 1 treatment IEP RGD PMID:31836774 RGD:32733624 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
peritoneal mesothelioma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lats1 large tumor suppressor kinase 1 ISO ClinVar Annotator: match by term: Malignant peritoneal mesothelioma ClinVar NCBI chr 1:2,160,411...2,193,640
Ensembl chr 1:2,160,411...2,193,640
JBrowse link
G Lats2 large tumor suppressor kinase 2 ISO ClinVar Annotator: match by term: Malignant peritoneal mesothelioma ClinVar NCBI chr15:31,825,068...31,877,193
Ensembl chr15:31,825,092...31,877,220
JBrowse link
G Mecom MDS1 and EVI1 complex locus ISO ClinVar Annotator: match by term: Malignant peritoneal mesothelioma ClinVar NCBI chr 2:112,909,353...113,464,583
Ensembl chr 2:112,909,321...113,464,590
JBrowse link
G Traf7 TNF receptor associated factor 7 ISO DNA:missense mutations:multiple RGD PMID:30171198 RGD:151356964 NCBI chr10:13,533,570...13,552,290
Ensembl chr10:13,533,570...13,552,203
JBrowse link
Peritoneal Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calb2 calbindin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23621518 NCBI chr 4:78,060,494...78,195,007
Ensembl chr 4:78,060,494...78,194,865
JBrowse link
G Mcam melanoma cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 PMID:23621518 NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571
JBrowse link
G Mlana melan-A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 1:227,469,537...227,483,343
Ensembl chr 1:227,469,537...227,483,343
JBrowse link
G Muc1 mucin 1, cell surface associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Pdpn podoplanin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
JBrowse link
G Slc2a1 solute carrier family 2 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Vim vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Wt1 WT1 transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643
JBrowse link
peritoneum cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca1 BRCA1, DNA repair associated ISO ClinVar Annotator: match by term: Peritoneum cancer ClinVar PMID:20104584 PMID:25741868 PMID:26467025 PMID:28492532 PMID:29446198 More... NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta severity ISO associated with stomach cancer RGD PMID:26514342 RGD:11556383 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha sexual_dimorphism ISO associated with stomach cancer;protein:altered expression:peritoneum (human) RGD PMID:32724431 RGD:42722625 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
JBrowse link
G Prg2 proteoglycan 2, pro eosinophil major basic protein severity ISO associated with colorectal cancer;protein:decreased expression:colorectum, eosinophil (human) RGD PMID:28439450 RGD:40902993 NCBI chr 3:70,062,535...70,066,102
Ensembl chr 3:70,062,535...70,066,101
JBrowse link
peritonitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin IEP RGD PMID:16538883 RGD:1598512 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Ada adenosine deaminase IDA
IEP
protein:increased expression:peritoneal fluid
protein:decreased activity:serum
RGD PMID:15969953 PMID:15373900 RGD:1624309, RGD:152995406 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Aldob aldolase, fructose-bisphosphate B IEP mRNA:increased expression:liver (rat) RGD PMID:8403244 RGD:2313429 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO RGD PMID:18941242 RGD:5509607 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Becn1 beclin 1 IEP protein:increased expression: RGD PMID:22001349 RGD:6483066 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G C5 complement C5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19284563 PMID:19346296 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
JBrowse link
G Cd40 CD40 molecule ISO RGD PMID:15780086 RGD:7248438 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd40lg CD40 ligand ISO RGD PMID:15780086 RGD:7248438 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Esr1 estrogen receptor 1 treatment IDA RGD PMID:23063870 RGD:8553243 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 treatment IDA RGD PMID:23063870 RGD:8553243 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Foxp1 forkhead box P1 ISO human gene in a mouse model RGD PMID:18799727 RGD:11561898 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha exacerbates ISO RGD PMID:20716766 RGD:42722627 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16713974 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO RGD PMID:18962899 RGD:4140945 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gusb glucuronidase, beta IEP protein:altered expression:peritoneal cells (rat) RGD PMID:185091 RGD:42722008 NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G Ifng interferon gamma treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:19804847 PMID:28593696 RGD:14974254 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il6 interleukin 6 ISO RGD PMID:26601826 RGD:14975296 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgam integrin subunit alpha M ameliorates ISO DNA:missense mutation:CDS:p.I332G (mouse) RGD PMID:32938725 RGD:329853755 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgb2 integrin subunit beta 2 ameliorates ISO RGD PMID:18239087 RGD:127345091 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Mir155 microRNA 155 ISO associated with Hypothermia RGD PMID:25231976 PMID:24708712 RGD:21079419, RGD:21079469 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir21 microRNA 21 ISO RGD PMID:26382295 RGD:11342022 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Nppa natriuretic peptide A ISO RGD PMID:23422200 RGD:7247713 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 treatment ISO RGD PMID:8113674 RGD:11541096 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Plat plasminogen activator, tissue type ISO RGD PMID:18571586 RGD:6484139 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Plau plasminogen activator, urokinase ISO RGD PMID:18571586 RGD:6484139 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO RGD PMID:20693875 RGD:6484122 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Ptgis prostaglandin I2 synthase ameliorates ISO RGD PMID:26611322 RGD:11536046 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451
JBrowse link
G Tmem67 transmembrane protein 67 ISO ClinVar Annotator: match by term: Peritonitis ClinVar PMID:19466712 PMID:19508969 PMID:19540516 PMID:19574260 PMID:20607301 More... NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334
JBrowse link
G Tnf tumor necrosis factor IEP
ISO
protein:increased expression:plasma RGD PMID:20819637 PMID:26601826 RGD:4143378, RGD:14975296 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Xdh xanthine dehydrogenase IEP RGD PMID:1443884 PMID:8367813 RGD:13210513, RGD:13210579 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
Pneumoperitoneum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 IEP mRNA, protein:increased expression:kidney, peritubular capillary, proximal tubule (rat) RGD PMID:11285964 RGD:8662302 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Xdh xanthine dehydrogenase IDA protein:increased activity:kidney RGD PMID:18629585 RGD:7247655 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
Septic Peritonitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec4m C-type lectin domain family 4 member M susceptibility ISO RGD PMID:15583012 RGD:39939009 NCBI chr12:1,915,902...1,924,529
Ensembl chr12:1,915,919...1,924,539
JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:8656607 RGD:11039538 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G F2 coagulation factor II, thrombin severity ISO RGD PMID:18927430 RGD:40818433 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F5 coagulation factor V disease_progression ISO RGD PMID:25690763 RGD:11564333 NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G Il27 interleukin 27 exacerbates ISO RGD PMID:16880260 RGD:126790504 NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582
JBrowse link
G Il6 interleukin 6 IEP protein:increased expression:plasma (rat) RGD PMID:19897171 RGD:11062137 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Kl Klotho disease_progression ISO RGD PMID:23364432 RGD:10403048 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
JBrowse link
G Mir155 microRNA 155 ISO associatd with liver cirrhosis RGD PMID:28074870 RGD:21079477 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 treatment ISO RGD PMID:11850627 RGD:737789 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pten phosphatase and tensin homolog ameliorates ISO associated with Escherichia Coli Infections RGD PMID:21521784 RGD:127285602 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Serpinf1 serpin family F member 1 ISO protein:increased expression:peritoneal fluid (human) RGD PMID:8869327 RGD:30296661 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19100
    disease of anatomical entity 18440
      gastrointestinal system disease 7176
        Peritoneal Diseases 81
          Chylous Ascites + 0
          Hemoperitoneum 0
          Mesenteric Ischemia 4
          Peritoneal Fibrosis 18
          Peritoneal Neoplasms + 19
          Peritoneal Panniculitis + 0
          Pneumoperitoneum 2
          mesenteric lymphadenitis 0
          mesenteric vascular occlusion 4
          peritonitis + 39
paths to the root