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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Head and Neck Neoplasms
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Accession:DOID:9006169 term browser browse the term
Definition:Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
Synonyms:exact_synonym: Head Neoplasms;   Head, Neck Neoplasms;   Neck Neoplasms;   UADT Neoplasm;   UADT Neoplasms;   Upper Aerodigestive Tract Neoplasms;   upper aerodigestive tract neoplasm
 narrow_synonym: Cancer of Head;   Cancer of Neck;   Cancer of the Head;   Cancer of the Neck;   Head Cancer;   Neck Cancer
 primary_id: MESH:D006258
 alt_id: RDO:0000780
 xref: EFO:0004284;   EFO:0005950


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Head and Neck Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Areg amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chrNW_004936598:1,276,599...1,283,612
Ensembl chrNW_004936598:1,274,565...1,283,746
JBrowse link
G Bap1 BRCA1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chrNW_004936473:3,239,009...3,247,806
Ensembl chrNW_004936473:3,239,010...3,247,806
JBrowse link
G Bcl2 BCL2 apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:18566236 NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921
JBrowse link
G Bcl2l1 BCL2 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18566236 NCBI chrNW_004936485:18,654,046...18,707,324 JBrowse link
G Cebpa CCAAT enhancer binding protein alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:17510391 NCBI chrNW_004936570:2,513,561...2,516,213 JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:7692001 NCBI chrNW_004936490:15,142,526...15,146,375
Ensembl chrNW_004936490:15,142,808...15,144,487
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19020767 NCBI chrNW_004936537:1,660,461...2,439,305
Ensembl chrNW_004936537:1,660,477...2,439,273
JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:12942316 PMID:15342401 PMID:16467544 PMID:23917044 RGD:5131641 NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit severity ISO mRNA:increased expression: : RGD PMID:26659720 RGD:11573297 NCBI chrNW_004936706:1,816,561...1,829,638
Ensembl chrNW_004936706:1,816,571...1,829,692
JBrowse link
G Fat1 FAT atypical cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23354438 NCBI chrNW_004936554:2,872,729...2,996,821
Ensembl chrNW_004936554:2,872,713...2,996,823
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Head and Neck Neoplasms ClinVar PMID:7668257 PMID:7719344 PMID:8651276 PMID:9677057 PMID:9700203 More... NCBI chrNW_004936486:10,506,680...10,606,272
Ensembl chrNW_004936486:10,507,097...10,602,019
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15557674 NCBI chrNW_004936529:997,943...999,123
Ensembl chrNW_004936529:998,150...998,987
JBrowse link
G Grp gastrin releasing peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chrNW_004936497:5,473,293...5,487,344
Ensembl chrNW_004936497:5,476,800...5,487,358
JBrowse link
G Mal mal, T cell differentiation protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19445022 NCBI chrNW_004937185:62,807...68,205
Ensembl chrNW_004937185:63,274...68,187
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chrNW_004936619:1,889,841...1,932,646
Ensembl chrNW_004936619:1,889,708...1,932,646
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chrNW_004936501:12,342,670...12,390,650
Ensembl chrNW_004936501:12,384,804...12,392,180
JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO DNA:insertion:promoter:g.-1607insG (human) RGD PMID:19843588 RGD:7207056 NCBI chrNW_004936551:5,167,909...5,175,149
Ensembl chrNW_004936551:5,168,044...5,174,857
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Head and Neck Neoplasms ClinVar PMID:15016963 PMID:15254419 PMID:15647370 PMID:15805248 PMID:16906227 More... NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073
JBrowse link
G Prame PRAME nuclear receptor transcriptional regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:16179254 NCBI chrNW_004936619:1,748,337...1,751,748 JBrowse link
G Rad51 RAD51 recombinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22613844 NCBI chrNW_004936471:4,119,020...4,136,811
Ensembl chrNW_004936471:4,114,530...4,136,248
JBrowse link
G Rarb retinoic acid receptor beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17549354 NCBI chrNW_004936473:16,983,829...17,146,517
Ensembl chrNW_004936473:16,983,600...17,148,885
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 ISO mRNA:increased expression:head and neck (human) RGD PMID:21764905 RGD:11039047 NCBI chrNW_004936594:1,775,412...1,778,389
Ensembl chrNW_004936594:1,777,376...1,778,164
JBrowse link
G Stat6 signal transducer and activator of transcription 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21765211 NCBI chrNW_004936646:1,297,530...1,312,508
Ensembl chrNW_004936646:1,296,290...1,312,157
JBrowse link
G Tgfa transforming growth factor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chrNW_004936491:14,659,089...14,758,614
Ensembl chrNW_004936491:14,657,100...14,758,848
JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Head and Neck Neoplasms ClinVar PMID:9067756 PMID:11370630 PMID:11782540 PMID:16818505 PMID:17606709 More... NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425
JBrowse link
G Tyms thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19020767 NCBI chrNW_004936550:33,797...42,233
Ensembl chrNW_004936550:34,048...41,840
JBrowse link
G Urod uroporphyrinogen decarboxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21270338 NCBI chrNW_004936474:26,207,169...26,210,599
Ensembl chrNW_004936474:26,207,169...26,210,623
JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16499871 NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22613844 NCBI chrNW_004936621:1,462,441...1,474,937
Ensembl chrNW_004936621:1,462,428...1,473,868
JBrowse link
acoustic neuroma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Artn artemin ISO mRNA:increased expression:peripheral nerve: RGD PMID:19937367 RGD:8655552 NCBI chrNW_004936474:25,252,510...25,254,221
Ensembl chrNW_004936474:25,252,684...25,253,810
JBrowse link
G Bdnf brain derived neurotrophic factor ISO mRNA:increased expression:peripheral nerve: RGD PMID:19937367 RGD:8655552 NCBI chrNW_004936540:5,530,081...5,582,765
Ensembl chrNW_004936540:5,529,942...5,585,014
JBrowse link
G Cav1 caveolin 1 ISO RGD PMID:20881564 RGD:8661782 NCBI chrNW_004936589:2,504,235...2,536,778
Ensembl chrNW_004936589:2,504,224...2,537,170
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A ISO mRNA,protein:decreased expression:myelinated nerve: RGD PMID:20600642 RGD:8661792 NCBI chrNW_004936476:22,717,308...22,725,127
Ensembl chrNW_004936476:22,717,260...22,725,182
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility ISO DNA:missense mutation:cds:p.D312N (rs1799793) (human) RGD PMID:20150366 RGD:5688735 NCBI chrNW_004936706:1,816,561...1,829,638
Ensembl chrNW_004936706:1,816,571...1,829,692
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 disease_progression ISO RGD PMID:15354013 RGD:11567268 NCBI chrNW_004936710:1,760,365...1,815,269
Ensembl chrNW_004936710:1,760,089...1,815,508
JBrowse link
G Gdnf glial cell derived neurotrophic factor ISO mRNA:increased expression:peripheral nerve: RGD PMID:19937367 RGD:8655552 NCBI chrNW_004936518:4,291,391...4,310,752
Ensembl chrNW_004936518:4,288,154...4,310,753
JBrowse link
G Igf1 insulin like growth factor 1 susceptibility ISO protein:increased expression:serum: RGD PMID:21788435 RGD:8548833 NCBI chrNW_004936492:11,709,623...11,784,028
Ensembl chrNW_004936492:11,709,222...11,778,351
JBrowse link
G Igfbp3 insulin like growth factor binding protein 3 susceptibility ISO protein:increased expression:serum: RGD PMID:21788435 RGD:8548833 NCBI chrNW_004936478:20,511,490...20,518,251
Ensembl chrNW_004936478:20,510,137...20,518,306
JBrowse link
G LOC101973029 cytochrome P450 2E1 ISO DNA:snp:promoter:c.-1053C>T (human) RGD PMID:12540498 RGD:1358568 NCBI chrNW_004936486:19,691,822...19,702,684
Ensembl chrNW_004936486:19,691,822...19,702,102
JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor ISO protein:decreased expression:myelinated nerve: RGD PMID:20600642 RGD:8661792 NCBI chrNW_004936657:3,536,212...3,622,999
Ensembl chrNW_004936657:3,536,141...3,623,821
JBrowse link
G Vegfa vascular endothelial growth factor A ISO RGD PMID:14660915 RGD:8547959 NCBI chrNW_004936476:16,245,134...16,261,180
Ensembl chrNW_004936476:16,247,100...16,260,673
JBrowse link
adenoid cystic carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 (Colton blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936478:7,146,997...7,160,369
Ensembl chrNW_004936478:7,147,027...7,160,401
JBrowse link
G Arid1a AT-rich interaction domain 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936474:11,148,857...11,197,312 JBrowse link
G Arid2 AT-rich interaction domain 2 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chrNW_004936512:4,020,303...4,199,390
Ensembl chrNW_004936512:4,020,966...4,196,459
JBrowse link
G Arid4b AT-rich interaction domain 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936484:17,116,304...17,257,640
Ensembl chrNW_004936484:17,116,229...17,258,277
JBrowse link
G Arid5b AT-rich interaction domain 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936614:1,072,263...1,252,573
Ensembl chrNW_004936614:1,072,260...1,252,283
JBrowse link
G Aspm assembly factor for spindle microtubules ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936567:6,653,382...6,701,856
Ensembl chrNW_004936567:6,653,728...6,701,752
JBrowse link
G Atm ATM serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936551:359,134...534,672
Ensembl chrNW_004936551:359,362...532,211
JBrowse link
G Atr ATR serine/threonine kinase treatment ISO RGD PMID:32001675 RGD:150340693 NCBI chrNW_004936540:4,074,543...4,178,859
Ensembl chrNW_004936540:4,074,570...4,178,898
JBrowse link
G Atrx ATRX chromatin remodeler ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936683:2,496,307...2,718,539
Ensembl chrNW_004936683:2,495,959...2,718,620
JBrowse link
G Bap1 BRCA1 associated protein 1 ISO ClinVar Annotator: match by term: Adenocystic carcinoma | ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar PMID:21642991 PMID:24894717 PMID:26166446 PMID:26452128 PMID:28492532 NCBI chrNW_004936473:3,239,009...3,247,806
Ensembl chrNW_004936473:3,239,010...3,247,806
JBrowse link
G Bcl11a BCL11 transcription factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936491:6,021,340...6,118,103
Ensembl chrNW_004936491:6,021,343...6,118,568
JBrowse link
G Bcor BCL6 corepressor ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chrNW_004936502:6,764,043...6,812,194
Ensembl chrNW_004936502:6,764,907...6,792,916
JBrowse link
G Bcorl1 BCL6 corepressor like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936479:1,539,676...1,605,647
Ensembl chrNW_004936479:1,538,051...1,606,344
JBrowse link
G Brca1 BRCA1 DNA repair associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936490:17,735,444...17,801,456 JBrowse link
G Brd1 bromodomain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936629:909,716...958,620
Ensembl chrNW_004936629:909,680...958,896
JBrowse link
G Ccnd1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 Ensembl chrNW_004936599:973,838...983,316 JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17520682 NCBI chrNW_004936475:18,990,529...19,065,954
Ensembl chrNW_004936475:18,990,474...19,067,203
JBrowse link
G Cmtr2 cap methyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936475:22,434,009...22,441,350
Ensembl chrNW_004936475:22,434,180...22,440,846
JBrowse link
G Cntn6 contactin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936577:1,108,502...1,393,706
Ensembl chrNW_004936577:1,167,211...1,393,521
JBrowse link
G Crebbp CREB binding protein ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 More... NCBI chrNW_004936694:552,447...663,237
Ensembl chrNW_004936694:553,753...663,617
JBrowse link
G Dapk1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936680:2,842,930...3,020,757
Ensembl chrNW_004936680:2,842,547...3,021,058
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936557:1,347,991...1,389,836
Ensembl chrNW_004936557:1,347,991...1,389,836
JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936581:3,433,760...3,467,863
Ensembl chrNW_004936581:3,437,489...3,467,869
JBrowse link
G Efhd1 EF-hand domain family member D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936525:4,445,779...4,484,674
Ensembl chrNW_004936525:4,445,773...4,484,680
JBrowse link
G En1 engrailed homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936469:51,439,944...51,451,194 JBrowse link
G Ep300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936492:696,982...778,132
Ensembl chrNW_004936492:696,960...778,138
JBrowse link
G Erbin erbb2 interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936480:3,155,934...3,293,224
Ensembl chrNW_004936480:3,154,690...3,293,230
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936512:10,556,269...10,576,582
Ensembl chrNW_004936512:10,556,672...10,576,588
JBrowse link
G Fanca FA complementation group A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936641:281,119...319,796
Ensembl chrNW_004936641:281,073...324,053
JBrowse link
G Fat1 FAT atypical cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936554:2,872,729...2,996,821
Ensembl chrNW_004936554:2,872,713...2,996,823
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:26619011 NCBI chrNW_004936689:2,261,163...2,449,951
Ensembl chrNW_004936689:2,259,477...2,344,764
JBrowse link
G Fgf16 fibroblast growth factor 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936683:2,454,067...2,463,653
Ensembl chrNW_004936683:2,454,067...2,463,635
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar PMID:26619011 NCBI chrNW_004936486:10,506,680...10,606,272
Ensembl chrNW_004936486:10,507,097...10,602,019
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936597:1,388,394...1,397,731
Ensembl chrNW_004936597:1,385,624...1,397,758
JBrowse link
G Foxo3 forkhead box O3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936564:4,788,036...4,907,600
Ensembl chrNW_004936564:4,787,992...4,903,837
JBrowse link
G Foxp2 forkhead box P2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936589:4,120,162...4,661,258
Ensembl chrNW_004936589:4,123,182...4,382,005
JBrowse link
G Gas2 growth arrest specific 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936654:3,326,557...3,448,930
Ensembl chrNW_004936654:3,326,511...3,448,872
JBrowse link
G Gas6 growth arrest specific 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936472:27,116...57,158
Ensembl chrNW_004936472:32,123...54,028
JBrowse link
G Gins2 GINS complex subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936641:2,757,150...2,775,904
Ensembl chrNW_004936641:2,757,150...2,776,681
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936576:2,353,874...2,411,747
Ensembl chrNW_004936576:2,353,761...2,411,425
JBrowse link
G Homer3 homer scaffold protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936596:2,406,427...2,413,651
Ensembl chrNW_004936596:2,406,326...2,413,604
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chrNW_004936888:375,372...378,125
Ensembl chrNW_004936888:375,377...377,958
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More... NCBI chrNW_004936950:334,894...349,221
Ensembl chrNW_004936950:334,934...348,363
JBrowse link
G Igfbp2 insulin like growth factor binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936586:671,760...696,783
Ensembl chrNW_004936586:672,091...696,692
JBrowse link
G Il17rd interleukin 17 receptor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936473:7,447,292...7,507,819
Ensembl chrNW_004936473:7,447,292...7,507,830
JBrowse link
G Insrr insulin receptor related receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936580:5,982,259...5,999,994
Ensembl chrNW_004936580:5,983,006...5,999,994
JBrowse link
G Irx4 iroquois homeobox 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936815:90,707...94,138
Ensembl chrNW_004936815:90,942...94,147
JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936596:2,815,782...2,819,100
Ensembl chrNW_004936596:2,815,821...2,819,020
JBrowse link
G Itgb4 integrin subunit beta 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936594:912,302...944,819
Ensembl chrNW_004936594:912,291...946,012
JBrowse link
G Jag1 jagged canonical Notch ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936485:8,857,688...8,894,270
Ensembl chrNW_004936485:8,857,669...8,895,315
JBrowse link
G Jak3 Janus kinase 3 ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:14615376 PMID:28492532 PMID:33040328 NCBI chrNW_004936596:3,212,593...3,224,426
Ensembl chrNW_004936596:3,212,593...3,224,048
JBrowse link
G Jmjd1c jumonji domain containing 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936753:1,413,935...1,645,974
Ensembl chrNW_004936753:1,414,240...1,645,161
JBrowse link
G Kansl1 KAT8 regulatory NSL complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936541:2,480,097...2,677,693
Ensembl chrNW_004936541:2,480,849...2,675,991
JBrowse link
G Kat6a lysine acetyltransferase 6A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936785:602,754...704,504
Ensembl chrNW_004936785:603,478...701,791
JBrowse link
G Kdm6a lysine demethylase 6A exacerbates ISO CTD Direct Evidence: marker/mechanism
DNA:mutations:multiple: (human)
DNA:splice-site mutation, missense mutations:splice junction, CDS:multiple: (human)
CTD
RGD
PMID:23685749 PMID:31483290 RGD:150429732 RGD:150429736 NCBI chrNW_004936502:10,980,303...11,196,711
Ensembl chrNW_004936502:10,980,118...11,196,163
JBrowse link
G Kdm6b lysine demethylase 6B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936595:1,077,318...1,099,082
Ensembl chrNW_004936595:1,089,544...1,097,595
JBrowse link
G Kmt2c lysine methyltransferase 2C disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:23685749 PMID:31483290 RGD:150429736 NCBI chrNW_004936527:7,310,885...7,508,032
Ensembl chrNW_004936527:7,312,721...7,506,365
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:6695174 PMID:12460918 PMID:15696205 PMID:16361624 PMID:16618717 More... NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523
JBrowse link
G Krt15 keratin 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936490:16,431,604...16,436,139
Ensembl chrNW_004936490:16,431,558...16,526,000
JBrowse link
G Krt5 keratin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936512:9,923,593...9,929,517
Ensembl chrNW_004936512:9,922,523...9,929,517
JBrowse link
G LOC101962705 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936637:985,706...1,154,670
Ensembl chrNW_004936637:560,298...1,151,850
JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chrNW_004936888:379,622...397,647
Ensembl chrNW_004936888:382,062...402,083
JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936479:21,373,917...22,062,498
Ensembl chrNW_004936479:21,373,746...21,920,214
JBrowse link
G Maml3 mastermind like transcriptional coactivator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936535:7,537,420...7,991,983
Ensembl chrNW_004936535:7,599,660...7,989,952
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936588:2,338,127...2,377,090
Ensembl chrNW_004936588:2,336,858...2,377,090
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936679:2,373,104...2,379,230 JBrowse link
G Mark2 microtubule affinity regulating kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936599:5,226,603...5,287,677
Ensembl chrNW_004936599:5,226,496...5,287,683
JBrowse link
G Mecom MDS1 and EVI1 complex locus ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chrNW_004936593:2,742,236...3,282,596
Ensembl chrNW_004936593:3,106,202...3,282,596
JBrowse link
G Mga MAX dimerization protein MGA ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936471:4,946,770...5,073,925
Ensembl chrNW_004936471:4,946,124...5,073,849
JBrowse link
G Mier2 MIER family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936588:25,272...46,226
Ensembl chrNW_004936588:25,253...46,246
JBrowse link
G Mlc1 modulator of VRAC current 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936629:696,592...719,363
Ensembl chrNW_004936629:696,451...719,416
JBrowse link
G Morf4l1 mortality factor 4 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936471:37,073,920...37,097,216
Ensembl chrNW_004936471:37,073,895...37,097,235
JBrowse link
G Myb MYB proto-oncogene, transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 PMID:26829750 NCBI chrNW_004936560:2,797,943...2,828,813
Ensembl chrNW_004936560:2,796,697...2,829,650
JBrowse link
G Mybl1 MYB proto-oncogene like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936496:7,395,541...7,436,295
Ensembl chrNW_004936496:7,395,533...7,436,358
JBrowse link
G Mycbp MYC binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936474:20,837,757...20,871,444
Ensembl chrNW_004936474:20,856,732...20,866,184
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936493:14,618,176...14,624,201
Ensembl chrNW_004936493:14,618,060...14,624,315
JBrowse link
G Neto2 neuropilin and tolloid like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936475:450,382...508,357
Ensembl chrNW_004936475:450,382...508,357
JBrowse link
G Nfib nuclear factor I B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936539:7,763,036...8,185,001
Ensembl chrNW_004936539:7,769,413...7,985,316
JBrowse link
G Notch1 notch receptor 1 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chrNW_004936669:1,292,016...1,334,061
Ensembl chrNW_004936669:1,292,088...1,332,428
JBrowse link
G Nsd1 nuclear receptor binding SET domain protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936597:1,426,318...1,577,193
Ensembl chrNW_004936597:1,425,974...1,572,715
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 treatment ISO RGD PMID:23027130 RGD:150519921 NCBI chrNW_004936483:13,912,904...14,291,881
Ensembl chrNW_004936483:13,909,109...14,291,887
JBrowse link
G Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936721:783,973...787,712
Ensembl chrNW_004936721:782,032...787,952
JBrowse link
G Pdzk1 PDZ domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936867:426,648...439,512 JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:15930273 PMID:17376864 PMID:18074223 PMID:19366826 PMID:22120714 More... NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936590:4,722,914...4,887,615
Ensembl chrNW_004936590:4,722,873...4,890,156
JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323
JBrowse link
G Pygb glycogen phosphorylase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936620:533,574...575,893
Ensembl chrNW_004936620:532,634...575,916
JBrowse link
G Rbfox2 RNA binding fox-1 homolog 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936492:4,624,013...4,826,715
Ensembl chrNW_004936492:4,645,167...4,821,291
JBrowse link
G Serpinf1 serpin family F member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936538:7,885,816...7,898,308
Ensembl chrNW_004936538:7,885,475...7,899,113
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936596:795,940...898,823
Ensembl chrNW_004936596:796,601...883,373
JBrowse link
G Sf3b1 splicing factor 3b subunit 1 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar PMID:25741868 PMID:26619011 NCBI chrNW_004936506:1,749,591...1,790,860
Ensembl chrNW_004936506:1,749,563...1,791,739
JBrowse link
G Slc24a3 solute carrier family 24 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936485:637,715...1,085,860
Ensembl chrNW_004936485:639,532...1,085,830
JBrowse link
G Slc3a2 solute carrier family 3 member 2 disease_progression ISO RGD PMID:23516127 RGD:151361211 NCBI chrNW_004936581:424,801...441,592 JBrowse link
G Slc7a5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:23516127 RGD:151361211 NCBI chrNW_004936641:1,513,110...1,538,955 JBrowse link
G Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chrNW_004936503:2,835,512...3,001,365
Ensembl chrNW_004936503:2,835,496...3,001,381
JBrowse link
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chrNW_004936619:1,276,239...1,308,945
Ensembl chrNW_004936619:1,275,362...1,308,913
JBrowse link
G Smarce1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936490:15,638,546...15,659,372
Ensembl chrNW_004936490:15,638,526...15,659,706
JBrowse link
G Smc1a structural maintenance of chromosomes 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936751:332,351...388,756
Ensembl chrNW_004936751:349,597...388,755
JBrowse link
G Son SON DNA and RNA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936500:8,721,155...8,752,906
Ensembl chrNW_004936500:8,722,087...8,752,844
JBrowse link
G Sox11 SRY-box transcription factor 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004937107:203,120...207,185 JBrowse link
G Srcap Snf2 related CREBBP activator protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936501:13,095,690...13,131,183
Ensembl chrNW_004936501:13,096,840...13,131,183
JBrowse link
G St3gal4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936572:5,806,897...5,851,557
Ensembl chrNW_004936572:5,806,894...5,841,550
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402
JBrowse link
G Tlk1 tousled like kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936509:1,315,802...1,403,993
Ensembl chrNW_004936509:1,317,534...1,404,705
JBrowse link
G Top2a DNA topoisomerase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936490:15,441,463...15,465,692
Ensembl chrNW_004936490:15,441,575...15,466,978
JBrowse link
G Tp53 tumor protein p53 disease_progression ISO ClinVar Annotator: match by term: Adenocystic carcinoma RGD
ClinVar
PMID:1673792 PMID:1686725 PMID:6736287 PMID:7707106 PMID:7881428 More... RGD:8547828 NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425
JBrowse link
G Uhrf1 ubiquitin like with PHD and ring finger domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chrNW_004936588:2,863,651...2,890,116
Ensembl chrNW_004936588:2,862,367...2,888,946
JBrowse link
G Vcan versican ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936469:2,585,142...2,688,029
Ensembl chrNW_004936469:2,585,134...2,688,029
JBrowse link
G Wnt5b Wnt family member 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936606:1,741,500...1,854,857
Ensembl chrNW_004936606:1,838,043...1,856,095
JBrowse link
G Xrn2 5'-3' exoribonuclease 2 ISO DNA:hypermethylation:3' utr: (human) RGD PMID:21692051 RGD:11041796 NCBI chrNW_004936620:4,069,956...4,145,212
Ensembl chrNW_004936620:4,069,934...4,145,745
JBrowse link
G Zim2 zinc finger imprinted 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chrNW_004936882:533,514...539,145 JBrowse link
adenoid squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf1a HNF1 homeobox A ISO RGD PMID:10489374 RGD:150540314 NCBI chrNW_004936668:62,103...81,549
Ensembl chrNW_004936668:67,535...81,505
JBrowse link
Barrett's adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpx3 glutathione peroxidase 3 ISO DNA:hypermethylation
DNA:hypermethylation:promoter
RGD PMID:16229808 PMID:18664505 RGD:151665354 RGD:151665749 NCBI chrNW_004936647:3,904,787...3,914,223
Ensembl chrNW_004936647:3,906,113...3,913,498
JBrowse link
G Gpx7 glutathione peroxidase 7 ISO DNA:hypermethylation:promoter RGD PMID:18664505 RGD:151665749 NCBI chrNW_004936522:8,381,678...8,388,800
Ensembl chrNW_004936522:8,381,377...8,389,357
JBrowse link
G LOC101977861 cytochrome P450 26A1 ISO RGD PMID:18059332 RGD:13782259 NCBI chrNW_004936601:1,810,572...1,815,927
Ensembl chrNW_004936601:1,809,992...1,814,074
JBrowse link
congenital heart defects, hamartomas of tongue, and polysyndactyly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wdpcp WD repeat containing planar cell polarity effector ISO ClinVar Annotator: match by term: Heart defect - tongue hamartoma - polysyndactyly syndrome | ClinVar Annotator: match by term: WDPCP-related condition OMIM
ClinVar
PMID:9536098 PMID:16199547 PMID:17576681 PMID:20671153 PMID:25326635 More... NCBI chrNW_004936491:8,238,644...8,749,172
Ensembl chrNW_004936491:8,239,284...8,485,636
JBrowse link
Cutaneous Telangiectasia and Cancer Syndrome, Familial term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atr ATR serine/threonine kinase ISO ClinVar Annotator: match by term: Cutaneous telangiectasia and cancer syndrome, familial OMIM
ClinVar
PMID:9536098 PMID:15987455 PMID:17010193 PMID:17576681 PMID:18414213 More... NCBI chrNW_004936540:4,074,543...4,178,859
Ensembl chrNW_004936540:4,074,570...4,178,898
JBrowse link
esophageal cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO protein:increased expression:esophagus (human) RGD PMID:27188433 RGD:152995510 NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO ClinVar Annotator: match by term: Esophageal cancer, alcohol-related, susceptibility to ClinVar PMID:2987944 PMID:4065146 PMID:6650498 PMID:7180842 PMID:7593603 More... NCBI chrNW_004936558:4,362,693...4,387,705
Ensembl chrNW_004936558:4,362,654...4,390,414
JBrowse link
G Bhlhe41 basic helix-loop-helix family member e41 ISO protein:increased expression:esophagus(human) RGD PMID:29890466 RGD:151665308 NCBI chrNW_004936548:1,306,939...1,314,678 JBrowse link
G Brca2 BRCA2 DNA repair associated ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:25741868 PMID:28492532 PMID:31911673 NCBI chrNW_004936472:26,945,659...27,017,693 JBrowse link
G Ctnna1 catenin alpha 1 disease_progression ISO RGD PMID:9863006 RGD:2289811 NCBI chrNW_004936531:7,865,907...8,036,020
Ensembl chrNW_004936531:7,865,820...8,037,935
JBrowse link
G Dcc DCC netrin 1 receptor ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:25741868 PMID:28492532 NCBI chrNW_004936497:10,122,078...11,169,900
Ensembl chrNW_004936497:10,122,617...11,169,803
JBrowse link
G Dlec1 DLEC1 cilia and flagella associated protein ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:25741868 NCBI chrNW_004936473:27,395,220...27,444,618 JBrowse link
G Gpx3 glutathione peroxidase 3 treatment ISO DNA:hypermethylation RGD PMID:33292587 RGD:151665781 NCBI chrNW_004936647:3,904,787...3,914,223
Ensembl chrNW_004936647:3,906,113...3,913,498
JBrowse link
G Hmox1 heme oxygenase 1 ISO protein:increased expression:esophagus RGD PMID:20498946 RGD:4145286 NCBI chrNW_004936492:5,042,353...5,049,216
Ensembl chrNW_004936492:5,042,330...5,049,311
JBrowse link
G Il10 interleukin 10 treatment ISO RGD PMID:26603620 RGD:152998997 NCBI chrNW_004936557:5,834,874...5,838,502
Ensembl chrNW_004936557:5,834,874...5,838,502
JBrowse link
G Il1b interleukin 1 beta treatment ISO RGD PMID:26603620 RGD:152998997 NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165
JBrowse link
G Il1r2 interleukin 1 receptor type 2 susceptibility ISO DNA:SNP:cds:rs11674595|rs2072472 (human) RGD PMID:31744444 RGD:152998961 NCBI chrNW_004936713:679,680...716,801
Ensembl chrNW_004936713:701,155...716,650
JBrowse link
G Il5 interleukin 5 treatment ISO RGD PMID:20232121 RGD:5134997 NCBI chrNW_004936647:2,647,982...2,651,477
Ensembl chrNW_004936647:2,648,241...2,651,430
JBrowse link
G LOC101957714 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial ameliorates ISO RNA:decreased expression:esophagus (human) RGD PMID:14760115 RGD:152025255 NCBI chrNW_004936514:1,467,460...1,480,185
Ensembl chrNW_004936514:1,467,261...1,480,185
JBrowse link
G LOC101969148 cytochrome P450 1A1 ISO RGD PMID:11833070 PMID:26782562 RGD:11554919 RGD:14700950 NCBI chrNW_004936471:33,682,730...33,688,332
Ensembl chrNW_004936471:33,682,730...33,688,332
JBrowse link
G Lzts1 leucine zipper tumor suppressor 1 ISO esophageal squamous cell carcinoma, OMIM:133239 RGD PMID:10097140 RGD:1600104 NCBI chrNW_004936555:4,330,878...4,384,883
Ensembl chrNW_004936555:4,330,787...4,384,932
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein ISO RGD PMID:10849326 RGD:1298988 NCBI chrNW_004936486:1,103,908...1,173,982
Ensembl chrNW_004936486:1,101,552...1,177,220
JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor ISO mRNA:splice variants:esophagus (human) RGD PMID:24527027 RGD:150519911 NCBI chrNW_004936473:27,672,237...27,676,339
Ensembl chrNW_004936473:27,671,797...27,676,372
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO protein:increased expression:esophagus (human) RGD PMID:27188433 RGD:152995510 NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073
JBrowse link
G Pten phosphatase and tensin homolog treatment ISO human gene and cells in a mouse model
protein:decreased expression:esophagus (human)
RGD PMID:20378992 PMID:27188433 RGD:127285592 RGD:152995510 NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323
JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO mRNA,protein:decreased expression:esophagus: RGD PMID:33862112 RGD:151232285 NCBI chrNW_004936530:9,312,965...9,315,593
Ensembl chrNW_004936530:9,312,965...9,316,165
JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:7664267 PMID:9395234 PMID:9536098 PMID:10789724 PMID:11212236 More... NCBI chrNW_004936473:21,324,669...21,409,430
Ensembl chrNW_004936473:21,324,658...21,409,430
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 severity
disease_progression
ISO DNA:SNP:3'utr: (rs583522) (human)
DNA:SNP:intron 6: (rs610604) (human)
RGD PMID:25354935 PMID:26598072 RGD:11075880 RGD:151347597 NCBI chrNW_004936560:5,124,955...5,138,988
Ensembl chrNW_004936560:5,128,843...5,138,345
JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:7887414 PMID:8023157 PMID:8118819 PMID:8164043 PMID:8825920 More... NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425
JBrowse link
G Wwox WW domain containing oxidoreductase ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:24456803 PMID:25411445 PMID:25741868 PMID:26467025 PMID:28492532 More... NCBI chrNW_004936475:26,342,245...27,209,563
Ensembl chrNW_004936475:26,342,220...27,208,711
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility ISO DNA:missense mutation:exon 9: p.T304A, c.910A>G (human) RGD PMID:24345911 RGD:150530620 NCBI chrNW_004936706:752,571...783,746
Ensembl chrNW_004936706:751,108...783,777
JBrowse link
esophageal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc7 baculoviral IAP repeat containing 7 disease_progression ISO mRNA:increased expression:esophagus (human) RGD PMID:31964418 RGD:153344516 NCBI chrNW_004936514:10,618,347...10,622,906
Ensembl chrNW_004936514:10,618,289...10,622,931
JBrowse link
G Brca2 BRCA2 DNA repair associated ISO ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:17972177 PMID:18431501 PMID:18627636 PMID:18779604 PMID:21120943 More... NCBI chrNW_004936472:26,945,659...27,017,693 JBrowse link
G Ctnnb1 catenin beta 1 ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:9065402 PMID:9065403 PMID:9294210 PMID:10027390 PMID:10192393 More... NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293
JBrowse link
G Dcc DCC netrin 1 receptor ISO ClinVar Annotator: match by term: Esophageal carcinoma, somatic ClinVar PMID:8187090 NCBI chrNW_004936497:10,122,078...11,169,900
Ensembl chrNW_004936497:10,122,617...11,169,803
JBrowse link
G Egfr epidermal growth factor receptor ISO ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:15623594 PMID:16205628 PMID:16707764 PMID:16863509 PMID:17653080 More... NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528
JBrowse link
G Ep300 E1A binding protein p300 ISO ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:26619011 NCBI chrNW_004936492:696,982...778,132
Ensembl chrNW_004936492:696,960...778,138
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:16397024 PMID:23220880 PMID:25157968 PMID:26619011 NCBI chrNW_004936490:14,887,062...14,910,038
Ensembl chrNW_004936490:14,887,043...14,909,956
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:25741868 PMID:26619011 NCBI chrNW_004936689:2,261,163...2,449,951
Ensembl chrNW_004936689:2,259,477...2,344,764
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:25157968 PMID:26619011 NCBI chrNW_004936486:10,506,680...10,606,272
Ensembl chrNW_004936486:10,507,097...10,602,019
JBrowse link
G Grb7 growth factor receptor bound protein 7 exacerbates ISO mRNA:increased expression:esophagus mucosa (human) RGD PMID:8988034 RGD:151347660 NCBI chrNW_004936490:14,912,010...14,925,380
Ensembl chrNW_004936490:14,917,372...14,925,337
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chrNW_004936888:375,372...378,125
Ensembl chrNW_004936888:375,377...377,958
JBrowse link
G Htra1 HtrA serine peptidase 1 disease_progression ISO mRNA,protein:decreased expression:esophagus (human) RGD PMID:22935172 RGD:152985525 NCBI chrNW_004936486:11,271,130...11,317,271
Ensembl chrNW_004936486:11,271,130...11,316,739
JBrowse link
G Jak2 Janus kinase 2 treatment ISO associated with Immune Deficiency Disease, human cells in mouse model RGD PMID:25724470 RGD:127285656 NCBI chrNW_004936503:111,722...243,627
Ensembl chrNW_004936503:110,963...241,867
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:16361624 PMID:16618717 PMID:18316791 PMID:19114683 PMID:19679400 More... NCBI chrNW_004936548:2,078,568...2,113,877
Ensembl chrNW_004936548:2,079,036...2,110,523
JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chrNW_004936888:379,622...397,647
Ensembl chrNW_004936888:382,062...402,083
JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 exacerbates ISO mRNA:decreased expression:espohagus (human) RGD PMID:32831056 RGD:155630592 NCBI chrNW_004936588:4,882,191...4,891,807
Ensembl chrNW_004936588:4,882,184...4,892,071
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:25157968 PMID:26619011 NCBI chrNW_004936470:20,480,844...20,485,955
Ensembl chrNW_004936470:20,480,829...20,485,965
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073
JBrowse link
G Rhoa ras homolog family member A ISO ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:26619011 NCBI chrNW_004936529:1,000,050...1,045,655
Ensembl chrNW_004936529:999,935...1,045,681
JBrowse link
G Slc7a5 solute carrier family 7 member 5 severity ISO RGD PMID:15906366 RGD:151361282 NCBI chrNW_004936641:1,513,110...1,538,955 JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:6604412 PMID:8898652 PMID:9214508 PMID:9285566 PMID:9582123 More... NCBI chrNW_004936497:12,242,869...12,278,012
Ensembl chrNW_004936497:12,249,140...12,278,123
JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment ISO associated with Immune Deficiency Disease, human cells in mouse model RGD PMID:25724470 RGD:127285656 NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402
JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:124622 PMID:253702 PMID:960674 PMID:1349175 PMID:1359493 More... NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425
JBrowse link
Esophageal Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21332314 NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chrNW_004936487:17,690,206...17,819,619
Ensembl chrNW_004936487:17,690,968...17,819,669
JBrowse link
G Actb actin beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chrNW_004936765:667,107...670,627
Ensembl chrNW_004936765:667,053...670,672
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:18500343 NCBI chrNW_004936520:3,467,003...3,489,754
Ensembl chrNW_004936520:3,467,003...3,490,997
JBrowse link
G Akap13 A-kinase anchoring protein 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chrNW_004936483:11,661,862...11,977,292 JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:8850269 NCBI chrNW_004936558:4,362,693...4,387,705
Ensembl chrNW_004936558:4,362,654...4,390,414
JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11406566 NCBI chrNW_004936677:3,232,183...3,241,307
Ensembl chrNW_004936677:3,232,183...3,241,253
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:21401805 NCBI chrNW_004936524:1,963,427...1,969,977
Ensembl chrNW_004936524:1,963,247...1,969,998
JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:17634542 NCBI chrNW_004936664:2,968,103...2,973,652
Ensembl chrNW_004936664:2,967,865...2,973,820
JBrowse link
G Bbc3 BCL2 binding component 3 ISO CTD Direct Evidence: therapeutic CTD PMID:16481741 NCBI chrNW_004936664:962,115...966,797 JBrowse link
G Bcl2 BCL2 apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921
JBrowse link
G Bcl2a1 BCL2 related protein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17634542 NCBI chrNW_004936471:37,981,851...37,993,097
Ensembl chrNW_004936471:37,981,772...37,993,116
JBrowse link
G Bsg basigin (Ok blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:36574092 NCBI chrNW_004936588:181,688...189,795
Ensembl chrNW_004936588:181,576...189,287
JBrowse link
G Casp8 caspase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17450141 PMID:21472143 NCBI chrNW_004936726:554,627...596,334
Ensembl chrNW_004936726:554,758...595,922
JBrowse link
G Ccnd1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12235107 Ensembl chrNW_004936599:973,838...983,316 JBrowse link
G Ccnh cyclin H ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chrNW_004936469:5,933,163...5,952,190
Ensembl chrNW_004936469:5,935,131...5,952,460
JBrowse link
G Cdh13 cadherin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18729198 NCBI chrNW_004936641:3,925,185...4,223,421
Ensembl chrNW_004936641:3,931,033...4,224,101
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A disease_progression ISO RGD PMID:11903577 RGD:8662379 NCBI chrNW_004936476:22,717,308...22,725,127
Ensembl chrNW_004936476:22,717,260...22,725,182
JBrowse link
G Cryab crystallin alpha B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chrNW_004936612:2,532,851...2,536,473
Ensembl chrNW_004936612:2,532,812...2,537,495
JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:7692001 NCBI chrNW_004936490:15,142,526...15,146,375
Ensembl chrNW_004936490:15,142,808...15,144,487
JBrowse link
G Dcc DCC netrin 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD NCBI chrNW_004936497:10,122,078...11,169,900
Ensembl chrNW_004936497:10,122,617...11,169,803
JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21298351 PMID:21468131 PMID:22042947 NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528
JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chrNW_004936623:3,115,357...3,130,289
Ensembl chrNW_004936623:3,115,081...3,128,183
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22042947 NCBI chrNW_004936490:14,887,062...14,910,038
Ensembl chrNW_004936490:14,887,043...14,909,956
JBrowse link
G Fas Fas cell surface death receptor ISO protein:decreased expression:esophageal mucosa: RGD PMID:9605741 RGD:11049151 NCBI chrNW_004936735:209,369...234,582 JBrowse link
G Faslg Fas ligand ISO protein:increased expression:esophageal mucosa: RGD PMID:9605741 RGD:11049151 NCBI chrNW_004936481:14,789,547...14,795,780 JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chrNW_004936709:1,243,149...1,247,782 JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chrNW_004936602:3,037,862...3,044,863
Ensembl chrNW_004936602:3,038,549...3,042,506
JBrowse link
G Gng7 G protein subunit gamma 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18219292 NCBI chrNW_004936588:1,501,386...1,565,557
Ensembl chrNW_004936588:1,503,836...1,507,178
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chrNW_004936651:2,756,559...3,401,806
Ensembl chrNW_004936651:2,762,380...3,401,808
JBrowse link
G Kdr kinase insert domain receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 PMID:35917945 NCBI chrNW_004936482:17,537,697...17,581,320
Ensembl chrNW_004936482:17,538,864...17,581,002
JBrowse link
G Lgals3 galectin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17634542 NCBI chrNW_004936697:20,861...38,568
Ensembl chrNW_004936697:27,145...38,586
JBrowse link
G LOC101954950 aromatase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chrNW_004936471:13,107,603...13,136,910
Ensembl chrNW_004936471:13,107,603...13,136,910
JBrowse link
G LOC101977861 cytochrome P450 26A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18059332 NCBI chrNW_004936601:1,810,572...1,815,927
Ensembl chrNW_004936601:1,809,992...1,814,074
JBrowse link
G Lzts1 leucine zipper tumor suppressor 1 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chrNW_004936555:4,330,878...4,384,883
Ensembl chrNW_004936555:4,330,787...4,384,932
JBrowse link
G Macir macrophage immunometabolism regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chrNW_004936523:1,273,812...1,292,837
Ensembl chrNW_004936523:1,275,214...1,292,854
JBrowse link
G Map3k3 mitogen-activated protein kinase kinase kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chrNW_004936541:4,276,371...4,345,239
Ensembl chrNW_004936541:4,276,371...4,344,008
JBrowse link
G Marchf8 membrane associated ring-CH-type finger 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chrNW_004936728:27,658...32,174 JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22042947 NCBI chrNW_004936589:2,280,803...2,390,179
Ensembl chrNW_004936589:2,280,799...2,390,179
JBrowse link
G Mlh3 mutL homolog 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16981255 NCBI chrNW_004936488:4,164,322...4,195,408
Ensembl chrNW_004936488:4,164,918...4,195,517
JBrowse link
G Mmp14 matrix metallopeptidase 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chrNW_004936722:1,447,189...1,457,632
Ensembl chrNW_004936722:1,447,335...1,457,611
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor treatment ISO RGD PMID:22844359 RGD:7207890 NCBI chrNW_004936470:20,480,844...20,485,955
Ensembl chrNW_004936470:20,480,829...20,485,965
JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15264214 NCBI chrNW_004936538:4,052,277...4,097,051
Ensembl chrNW_004936538:4,052,448...4,097,051
JBrowse link
G Nos3 nitric oxide synthase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chrNW_004936527:6,427,147...6,445,770
Ensembl chrNW_004936527:6,427,093...6,446,534
JBrowse link
G Nr1i2 nuclear receptor subfamily 1 group I member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21977915 NCBI chrNW_004936536:6,691,590...6,726,421
Ensembl chrNW_004936536:6,691,590...6,726,704
JBrowse link
G Phb1 prohibitin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chrNW_004936490:12,127,065...12,138,870 JBrowse link
G Prdx1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chrNW_004936474:26,641,776...26,653,291
Ensembl chrNW_004936474:26,639,259...26,653,328
JBrowse link
G Prdx2 peroxiredoxin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chrNW_004936659:1,894,423...1,897,690 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12189197 NCBI chrNW_004936487:10,745,465...10,758,812
Ensembl chrNW_004936487:10,745,327...10,758,823
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 susceptibility ISO mRNA,protein:increased expression:Esophagus
CTD Direct Evidence: marker/mechanism
DNA:SNPs: :-1195A > G, -765G > C (human)
RGD
CTD
PMID:11059772 PMID:16083713 PMID:16322294 PMID:17707579 PMID:22165968 RGD:5135528 RGD:5687745 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Rnf6 ring finger protein 6 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chrNW_004936948:57,806...67,875
Ensembl chrNW_004936948:55,699...67,972
JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:17121882 NCBI chrNW_004936469:24,313,850...24,315,318
Ensembl chrNW_004936469:24,314,105...24,314,434
JBrowse link
G Runx3 RUNX family transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18058463 NCBI chrNW_004936474:9,751,946...9,802,910
Ensembl chrNW_004936474:9,751,946...9,802,910
JBrowse link
G Sfn stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chrNW_004936474:11,274,927...11,279,427
Ensembl chrNW_004936474:11,246,534...11,279,433
JBrowse link
G Slc30a7 solute carrier family 30 member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chrNW_004936748:910,542...985,601
Ensembl chrNW_004936748:910,511...987,094
JBrowse link
G Smyd2 SET and MYND domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25825497 NCBI chrNW_004936628:3,917,898...3,965,382
Ensembl chrNW_004936628:3,918,230...3,965,387
JBrowse link
G Snai2 snail family transcriptional repressor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chrNW_004936590:3,813,916...3,817,642
Ensembl chrNW_004936590:3,813,888...3,817,642
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11053990 PMID:15986332 NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781
JBrowse link
G Sst somatostatin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17999418 NCBI chrNW_004936578:2,464,310...2,465,673
Ensembl chrNW_004936578:2,464,212...2,465,701
JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10789724 NCBI chrNW_004936473:21,324,669...21,409,430
Ensembl chrNW_004936473:21,324,658...21,409,430
JBrowse link
G Tgm2 transglutaminase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chrNW_004936561:3,178,244...3,207,551
Ensembl chrNW_004936561:3,178,293...3,207,561
JBrowse link
G Tp53 tumor protein p53 ISO protein:increased expression:esophageal mucosa:
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12706858 PMID:16778087 PMID:17634542 PMID:26192916 PMID:26439224 RGD:11075085 RGD:8547873 NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425
JBrowse link
G Tpm1 tropomyosin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chrNW_004936471:23,643,645...23,670,775
Ensembl chrNW_004936471:23,643,613...23,670,775
JBrowse link
G Tpm4 tropomyosin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chrNW_004936596:4,406,301...4,423,775
Ensembl chrNW_004936596:4,406,283...4,418,932
JBrowse link
G Trmt11 tRNA methyltransferase 11 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chrNW_004936639:3,442,026...3,494,303
Ensembl chrNW_004936639:3,440,703...3,494,362
JBrowse link
G Tufm Tu translation elongation factor, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chrNW_004936501:11,859,558...11,863,689
Ensembl chrNW_004936501:11,859,552...11,865,747
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15930319 NCBI chrNW_004936482:8,551,749...8,563,586
Ensembl chrNW_004936482:8,551,603...8,563,651
JBrowse link
G Wif1 WNT inhibitory factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17384664 NCBI chrNW_004936545:3,263,646...3,334,163
Ensembl chrNW_004936545:3,263,623...3,333,937
JBrowse link
G Wwox WW domain containing oxidoreductase ISO CTD Direct Evidence: marker/mechanism CTD NCBI chrNW_004936475:26,342,245...27,209,563
Ensembl chrNW_004936475:26,342,220...27,208,711
JBrowse link
G Xiap X-linked inhibitor of apoptosis ISO CTD Direct Evidence: marker/mechanism CTD PMID:17611394 NCBI chrNW_004936479:6,677,533...6,724,800
Ensembl chrNW_004936479:6,677,526...6,722,116
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21347786 NCBI chrNW_004936621:1,462,441...1,474,937
Ensembl chrNW_004936621:1,462,428...1,473,868
JBrowse link
esophagus adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase onset ISO DNA:SNP:3'utr: (rs4740363) (human) RGD PMID:21472143 RGD:126925218 NCBI chrNW_004936487:17,690,206...17,819,619
Ensembl chrNW_004936487:17,690,968...17,819,669
JBrowse link
G Arid1a AT-rich interaction domain 1A disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:23525077 PMID:31906887 RGD:127285649 NCBI chrNW_004936474:11,148,857...11,197,312 JBrowse link
G Barx1 BARX homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24121790 NCBI chrNW_004937000:88,529...96,794
Ensembl chrNW_004937000:88,529...92,147
JBrowse link
G Bcl2 BCL2 apoptosis regulator onset ISO DNA:SNPs:3'utr: (rs720321, rs17757541) (human) RGD PMID:21472143 RGD:126925218 NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921
JBrowse link
G Becn1 beclin 1 ISO RGD PMID:22301112 RGD:11561943 NCBI chrNW_004936490:17,518,100...17,531,126
Ensembl chrNW_004936490:17,517,751...17,531,151
JBrowse link
G Birc3 baculoviral IAP repeat containing 3 treatment ISO RGD PMID:26291056 RGD:152999007 NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555
JBrowse link
G Casp8 caspase 8 onset ISO DNA:SNP:5'utr: (rs1035142) (human) RGD PMID:21472143 RGD:126925218 NCBI chrNW_004936726:554,627...596,334
Ensembl chrNW_004936726:554,758...595,922
JBrowse link
G Cdc5l cell division cycle 5 like disease_progression ISO protein:increased expression:esophageal mucosa (human) RGD PMID:15725809 RGD:10047052 NCBI chrNW_004936476:15,647,470...15,698,095
Ensembl chrNW_004936476:15,648,678...15,698,106
JBrowse link
G Crtc1 CREB regulated transcription coactivator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24121790 NCBI chrNW_004936596:2,551,621...2,625,327
Ensembl chrNW_004936596:2,551,506...2,625,327
JBrowse link
G Dock2 dedicator of cytokinesis 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chrNW_004936609:4,695,202...5,099,038
Ensembl chrNW_004936609:4,695,628...5,099,038
JBrowse link
G Elmo1 engulfment and cell motility 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chrNW_004936478:12,308,255...12,754,957
Ensembl chrNW_004936478:12,306,450...12,754,963
JBrowse link
G Emx2 empty spiracles homeobox 2 ISO protein:decreased expression:esophagus (human) RGD PMID:31432154 RGD:153323302 NCBI chrNW_004936486:7,313,689...7,319,971
Ensembl chrNW_004936486:7,313,190...7,319,995
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit susceptibility ISO DNA:snps:cds, 3' utr:c.354C>T, c.8092C>A (human) RGD PMID:18478337 RGD:13207314 NCBI chrNW_004936706:1,854,938...1,867,521
Ensembl chrNW_004936706:1,852,359...1,867,745
JBrowse link
G Fas Fas cell surface death receptor ISO associated with Barrett Esophagus;protein:increased expression:esophageal mucosa (human) RGD PMID:10340890 RGD:8662425 NCBI chrNW_004936735:209,369...234,582 JBrowse link
G Foxa1 forkhead box A1 ISO protein:increased expression:esophagus RGD PMID:12234996 RGD:151665758 NCBI chrNW_004936494:11,529,546...11,535,224
Ensembl chrNW_004936494:11,529,546...11,535,224
JBrowse link
G Foxp1 forkhead box P1 ISO CTD Direct Evidence: marker/mechanism
DNA:snps:intron, enhancer:g.70959438A>G, g.70879779A>C (rs9837992, rs2687201) (human)
CTD
RGD
PMID:24121790 PMID:26383589 RGD:11535321 NCBI chrNW_004936603:2,631,781...3,146,104
Ensembl chrNW_004936603:2,632,274...2,830,324
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide onset ISO DNA:SNP:5'utr: (rs696217) (human) RGD PMID:21472143 RGD:126925218 NCBI chrNW_004936602:3,037,862...3,044,863
Ensembl chrNW_004936602:3,038,549...3,042,506
JBrowse link
G Gpx3 glutathione peroxidase 3 susceptibility ISO DNA:SNPs:intron: (rs4958872, rs3792797) (human) RGD PMID:22715394 RGD:152995500 NCBI chrNW_004936647:3,904,787...3,914,223
Ensembl chrNW_004936647:3,906,113...3,913,498
JBrowse link
G Grb7 growth factor receptor bound protein 7 treatment
exacerbates
ISO human cells in a mouse model RGD PMID:31809243 PMID:32737994 RGD:151347656 RGD:151347659 NCBI chrNW_004936490:14,912,010...14,925,380
Ensembl chrNW_004936490:14,917,372...14,925,337
JBrowse link
G Kdr kinase insert domain receptor onset ISO DNA:SNP:5'utr: (rs11941492) (human) RGD PMID:21472143 RGD:126925218 NCBI chrNW_004936482:17,537,697...17,581,320
Ensembl chrNW_004936482:17,538,864...17,581,002
JBrowse link
G LOC101954950 aromatase onset ISO DNA:SNP:5'utr: (rs2445762) (human) RGD PMID:21472143 RGD:126925218 NCBI chrNW_004936471:13,107,603...13,136,910
Ensembl chrNW_004936471:13,107,603...13,136,910
JBrowse link
G LOC101957714 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial treatment ISO mRNA:increased expression:esophagus (human) RGD PMID:30187205 RGD:151665176 NCBI chrNW_004936514:1,467,460...1,480,185
Ensembl chrNW_004936514:1,467,261...1,480,185
JBrowse link
G Mmp1 matrix metallopeptidase 1 susceptibility ISO DNA:insertion:promoter:g.-1607insG rs1799750 (human) RGD PMID:19321798 RGD:7207058 NCBI chrNW_004936551:5,167,909...5,175,149
Ensembl chrNW_004936551:5,168,044...5,174,857
JBrowse link
G Mmp12 matrix metallopeptidase 12 ISO DNA:snp:promoter:g.-82A>G rs2276109 (human) RGD PMID:19321798 RGD:7207058 NCBI chrNW_004936551:5,107,567...5,117,843
Ensembl chrNW_004936551:5,106,285...5,117,843
JBrowse link
G Mmp14 matrix metallopeptidase 14 onset ISO DNA:SNP:5'utr: (rs2236302) (human) RGD PMID:21472143 RGD:126925218 NCBI chrNW_004936722:1,447,189...1,457,632
Ensembl chrNW_004936722:1,447,335...1,457,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased expression:esophagus RGD PMID:25562781 RGD:13204790 NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793
JBrowse link
G Nell1 neural EGFL like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17452981 NCBI chrNW_004936654:1,591,016...2,392,496
Ensembl chrNW_004936654:1,591,847...2,394,692
JBrowse link
G Nos3 nitric oxide synthase 3 onset ISO DNA:SNP:3'utr: (rs2070744) (human) RGD PMID:21472143 RGD:126925218 NCBI chrNW_004936527:6,427,147...6,445,770
Ensembl chrNW_004936527:6,427,093...6,446,534
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO mRNA,protein:increased expression:Esophagus RGD PMID:22165968 RGD:5687745 NCBI chrNW_004936487:10,745,465...10,758,812
Ensembl chrNW_004936487:10,745,327...10,758,823
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 disease_progression ISO CTD Direct Evidence: marker/mechanism
protein: increased expression: esophagus
CTD
RGD
PMID:12055587 PMID:12507933 RGD:13207437 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Slc22a18 solute carrier family 22 member 18 disease_progression ISO DNA:hypermethylation: (human) RGD PMID:23243219 RGD:150557426 NCBI chrNW_004936794:1,042,103...1,061,347
Ensembl chrNW_004936794:1,042,224...1,061,345
JBrowse link
G Smad4 SMAD family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 PMID:24952744 NCBI chrNW_004936497:12,242,869...12,278,012
Ensembl chrNW_004936497:12,249,140...12,278,123
JBrowse link
G Smo smoothened, frizzled class receptor treatment ISO RGD PMID:23108119 RGD:150340553 NCBI chrNW_004936579:5,893,064...5,917,021
Ensembl chrNW_004936579:5,892,542...5,917,281
JBrowse link
G Sod2 superoxide dismutase 2 ISO RGD PMID:17785574 RGD:2317403 NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781
JBrowse link
G Spart spartin ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chrNW_004936472:30,467,975...30,525,880
Ensembl chrNW_004936472:30,467,964...30,504,624
JBrowse link
G Tlr4 toll like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chrNW_004936487:6,519,140...6,532,018
Ensembl chrNW_004936487:6,518,441...6,533,095
JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425
JBrowse link
G Vdr vitamin D receptor susceptibility
disease_progression
ISO DNA:SNPs,haplotype:exon:rs1989969,rs2238135 (human)
DNA:amplication: :
RGD PMID:24951052 PMID:25910066 RGD:11055189 RGD:13432070 NCBI chrNW_004936512:5,741,836...5,800,999
Ensembl chrNW_004936512:5,740,748...5,801,109
JBrowse link
esophagus squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21206495 NCBI chrNW_004936636:292,631...341,999
Ensembl chrNW_004936636:292,709...340,393
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936672:3,461,387...3,468,053
Ensembl chrNW_004936672:3,460,383...3,468,255
JBrowse link
G Ajuba ajuba LIM protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chrNW_004936722:1,331,568...1,341,854
Ensembl chrNW_004936722:1,331,566...1,341,863
JBrowse link
G Akt1 AKT serine/threonine kinase 1 disease_progression ISO protein:increased expression:esophagus (human) RGD PMID:32642408 RGD:152995512 NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:16639733 PMID:22960999 NCBI chrNW_004936558:4,362,693...4,387,705
Ensembl chrNW_004936558:4,362,654...4,390,414
JBrowse link
G Anxa1 annexin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936503:9,124,314...9,142,372
Ensembl chrNW_004936503:9,124,264...9,142,413
JBrowse link
G Atm ATM serine/threonine kinase disease_progression ISO Smoke Inhalation Injury; mRNA:increased expression:esophagus (human) RGD PMID:17019709 RGD:150340713 NCBI chrNW_004936551:359,134...534,672
Ensembl chrNW_004936551:359,362...532,211
JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25129146 NCBI chrNW_004936595:908,019...914,426
Ensembl chrNW_004936595:907,919...915,053
JBrowse link
G Axin1 axin 1 disease_progression ISO protein:decreased expression:esophagus (human) RGD PMID:12771989 RGD:150530473 NCBI chrNW_004936501:599,963...633,837
Ensembl chrNW_004936501:599,919...633,873
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding disease_progression ISO RGD PMID:28053542 RGD:153350138 NCBI chrNW_004936543:105,983...113,475
Ensembl chrNW_004936543:105,956...114,190
JBrowse link
G Azin1 antizyme inhibitor 1 ISO RGD PMID:24302582 RGD:14700707 NCBI chrNW_004936470:40,801,943...40,832,543
Ensembl chrNW_004936470:40,801,943...40,834,003
JBrowse link
G B2m beta-2-microglobulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936471:7,646,504...7,655,656
Ensembl chrNW_004936471:7,646,373...7,655,778
JBrowse link
G Blvrb biliverdin reductase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936661:2,808,998...2,818,123
Ensembl chrNW_004936661:2,808,950...2,818,178
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger ISO RGD PMID:21165554 RGD:126781701 NCBI chrNW_004936520:5,707,542...5,716,966
Ensembl chrNW_004936520:5,707,778...5,717,024
JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO protein:increased expression:esophagus RGD PMID:22364398 RGD:7242413 NCBI chrNW_004936534:4,707,658...4,871,865
Ensembl chrNW_004936534:4,709,064...4,871,023
JBrowse link
G Brca1 BRCA1 DNA repair associated ISO DNA:SNP: :rs799917 (human) RGD PMID:23749772 RGD:126925960 NCBI chrNW_004936490:17,735,444...17,801,456 JBrowse link
G Brca2 BRCA2 DNA repair associated ISO DNA:nonsense mutation: :p.K3326X (human) RGD PMID:21279724 RGD:11344913 NCBI chrNW_004936472:26,945,659...27,017,693 JBrowse link
G Bst2 bone marrow stromal cell antigen 2 disease_progression ISO RGD PMID:26832883 RGD:14398496
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18691855 NCBI chrNW_004936471:3,631,760...3,696,024
Ensembl chrNW_004936471:3,633,536...3,695,684
JBrowse link
G Ca1 carbonic anhydrase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936544:246,797...257,798
Ensembl chrNW_004936544:246,797...257,650
JBrowse link
G Ca12 carbonic anhydrase 12 severity ISO RGD PMID:26316888 RGD:155226859 NCBI chrNW_004936471:23,876,889...23,929,720
Ensembl chrNW_004936471:23,876,812...23,929,987
JBrowse link
G Ca2 carbonic anhydrase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936544:362,591...379,151
Ensembl chrNW_004936544:362,591...380,223
JBrowse link
G Calr calreticulin ameliorates ISO CTD Direct Evidence: marker/mechanism
human cells in a mouse model
CTD
RGD
PMID:19684620 PMID:21517111 PMID:23814025 RGD:150521679 RGD:150521703 NCBI chrNW_004936659:1,994,695...1,999,070
Ensembl chrNW_004936659:1,994,648...1,999,430
JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936690:1,184,644...1,223,732 JBrowse link
G Casp8 caspase 8 exacerbates ISO mRNA,protein:decreased expression:esophagus squamous epithelium (human) RGD PMID:31885720 RGD:153300949 NCBI chrNW_004936726:554,627...596,334
Ensembl chrNW_004936726:554,758...595,922
JBrowse link
G Cbx8 chromobox 8 severity ISO mRNA:increased expression:esophagus: RGD PMID:25197352 RGD:9587436 NCBI chrNW_004936594:3,906,714...3,911,604
Ensembl chrNW_004936594:3,906,697...3,911,714
JBrowse link
G Cchcr1 coiled-coil alpha-helical rod protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chrNW_004936837:809,958...821,604
Ensembl chrNW_004936837:809,921...821,608
JBrowse link
G Ccnd1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 Ensembl chrNW_004936599:973,838...983,316 JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A ISO CTD Direct Evidence: therapeutic CTD PMID:15375580 NCBI chrNW_004936476:22,717,308...22,725,127
Ensembl chrNW_004936476:22,717,260...22,725,182
JBrowse link
G Cdkn2b cyclin dependent kinase inhibitor 2B ISO DNA:SNPs: :rs615552, rs573687 (human) RGD PMID:23361049 RGD:7248756 NCBI chrNW_004936652:3,576,975...3,582,790
Ensembl chrNW_004936652:3,538,986...3,581,159
JBrowse link
G Cfl1 cofilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936599:3,678,724...3,682,314
Ensembl chrNW_004936599:3,677,804...3,682,307
JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit susceptibility ISO DNA:SNP: :rs667282(human)
mRNA:increased expression:esophagus (human)
RGD PMID:23844051 PMID:27610024 RGD:150524358 RGD:151361143 NCBI chrNW_004936471:36,451,070...36,492,774
Ensembl chrNW_004936471:36,452,965...36,492,618
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit exacerbates
disease_progression
ISO mRNA:increased expression:esophagus (human) RGD PMID:27610024 PMID:33603170 RGD:151361143 RGD:151667905 NCBI chrNW_004937351:32,324...46,871
Ensembl chrNW_004937351:34,921...47,246
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit ISO mRNA:increased expression:esophagus (human) RGD PMID:27610024 RGD:151361143 NCBI chrNW_004936471:36,408,471...36,425,571
Ensembl chrNW_004936471:36,408,447...36,426,021
JBrowse link
G Clic1 chloride intracellular channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936727:1,797,966...1,803,401
Ensembl chrNW_004936727:1,797,966...1,803,401
JBrowse link
G Clptm1l CLPTM1 like susceptibility
no_association
ISO DNA:SNP: :rs451360(human)
DNA:SNP: :rs401681(human)
mRNA:increased expression:esophagus
RGD PMID:24386361 PMID:25007268 PMID:25480402 PMID:26716642 RGD:11572962 RGD:150530488 RGD:150530497 RGD:150537098 NCBI chrNW_004936815:421,996...445,577
Ensembl chrNW_004936815:428,920...445,750
JBrowse link
G Col14a1 collagen type XIV alpha 1 chain disease_progression ISO DNA:hypermethylation RGD PMID:25050929 RGD:151665741 NCBI chrNW_004936470:26,440,606...26,643,015
Ensembl chrNW_004936470:26,440,615...26,643,015
JBrowse link
G Crabp1 cellular retinoic acid binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17438526 NCBI chrNW_004936471:36,665,641...36,672,626
Ensembl chrNW_004936471:36,662,647...36,672,606
JBrowse link
G Crebbp CREB binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chrNW_004936694:552,447...663,237
Ensembl chrNW_004936694:553,753...663,617
JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO mRNA:decreased expression:esophagus squamous epithelium (human) RGD PMID:32038997 RGD:150524298 NCBI chrNW_004936504:4,898,947...4,927,195
Ensembl chrNW_004936504:4,898,945...4,928,923
JBrowse link
G Cstb cystatin B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936500:502,444...503,307
Ensembl chrNW_004936500:502,237...503,578
JBrowse link
G Ctnnb1 catenin beta 1 ISO ClinVar Annotator: match by term: Esophageal squamous cell carcinoma ClinVar PMID:25157968 PMID:25741868 PMID:26619011 NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 disease_progression ISO protein:increased expression:esophagus squamous epithelium (human) RGD PMID:17171785 RGD:152023646 NCBI chrNW_004936469:39,794,613...39,798,448
Ensembl chrNW_004936469:39,794,584...39,798,459
JBrowse link
G Dab2ip DAB2 interacting protein severity ISO protein:decreased expression:esophagus (human) RGD PMID:30464518 RGD:151665168 NCBI chrNW_004936487:10,056,809...10,243,021
Ensembl chrNW_004936487:10,145,278...10,243,174
JBrowse link
G Dcc DCC netrin 1 receptor ISO OMIM NCBI chrNW_004936497:10,122,078...11,169,900
Ensembl chrNW_004936497:10,122,617...11,169,803
JBrowse link
G Dido1 death inducer-obliterator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chrNW_004936514:10,370,961...10,422,484
Ensembl chrNW_004936514:10,370,959...10,403,889
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta disease_progression ISO protein:increased expression:nucleus: RGD PMID:22213175 RGD:9589085 NCBI chrNW_004936485:19,547,836...19,570,716 JBrowse link
G Dpp4 dipeptidyl peptidase 4 ISO protein:increased expression: esophagus RGD PMID:24789592 RGD:152600903 NCBI chrNW_004936469:16,979,220...17,062,198
Ensembl chrNW_004936469:16,979,410...17,061,159
JBrowse link
G Efnb2 ephrin B2 severity
exacerbates
ameliorates
ISO mRNA:increased expression:esophagus squamous epithelium (human)
mRNA,protein:increased expression:esophagus squamous epithelium (human)
human cells in mouse model
RGD PMID:17611172 PMID:29190834 PMID:31885720 RGD:153300947 RGD:153300948 RGD:153300949 NCBI chrNW_004936472:5,138,751...5,181,630
Ensembl chrNW_004936472:5,138,745...5,181,668
JBrowse link
G Egfr epidermal growth factor receptor severity ISO protein:increased expression:esophagus (human)
ClinVar Annotator: match by term: Esophageal squamous cell carcinoma
RGD
ClinVar
PMID:10385363 PMID:23485129 PMID:25157968 RGD:5131486 NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528
JBrowse link
G Ehmt1 euchromatic histone lysine methyltransferase 1 disease_progression ISO protein:increased expression:esophagus:
protein:increased expression:esophagus mucosa:
RGD PMID:24649311 PMID:24805087 RGD:9589143 RGD:9590071 NCBI chrNW_004936669:321,580...450,061
Ensembl chrNW_004936669:321,249...423,018
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 disease_progression ISO protein:increased expression:esophagus mucosa: RGD PMID:24805087 RGD:9590071 NCBI chrNW_004936727:1,648,451...1,663,294
Ensembl chrNW_004936727:1,648,448...1,663,455
JBrowse link
G Ep300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17965222 PMID:25151357 NCBI chrNW_004936492:696,982...778,132
Ensembl chrNW_004936492:696,960...778,138
JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1 like 3 disease_progression ISO DNA:hypermethylation RGD PMID:25050929 RGD:151665741 NCBI chrNW_004936779:962,696...1,106,452
Ensembl chrNW_004936779:1,016,265...1,104,070
JBrowse link
G Ephb4 EPH receptor B4 exacerbates ISO mRNA,protein:increased expression:esophagus squamous epithelium (human) RGD PMID:31885720 RGD:153300949 NCBI chrNW_004936543:794,837...811,637
Ensembl chrNW_004936543:794,725...811,637
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 disease_progression
susceptibility
ISO protein:altered localization:nucleus
DNA:SNPs, haplotypes: :rs1595066 and rs16845990 (human)
RGD PMID:18000820 PMID:24916311 RGD:126781764 RGD:126781765 NCBI chrNW_004936586:4,065,767...5,100,690
Ensembl chrNW_004936586:4,066,498...5,100,035
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment ISO RGD PMID:23263828 RGD:11252162 NCBI chrNW_004936706:1,854,938...1,867,521
Ensembl chrNW_004936706:1,852,359...1,867,745
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression ISO RGD PMID:21165554 PMID:25613619 RGD:126781697 RGD:126781701 NCBI chrNW_004936527:5,024,077...5,069,152
Ensembl chrNW_004936527:5,024,068...5,063,939
JBrowse link
G Fanca FA complementation group A ISO DNA:missense mutation: :p.S858R (human) RGD PMID:21279724 RGD:11344913 NCBI chrNW_004936641:281,119...319,796
Ensembl chrNW_004936641:281,073...324,053
JBrowse link
G Fap fibroblast activation protein alpha ISO protein:increased expression: esophagus RGD PMID:24789592 RGD:152600903 NCBI chrNW_004936469:16,817,000...16,889,066
Ensembl chrNW_004936469:16,817,232...16,888,773
JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chrNW_004936594:5,591,785...5,609,886
Ensembl chrNW_004936594:5,592,609...5,608,972
JBrowse link
G Fat1 FAT atypical cadherin 1 ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:esophagus squamous epithelium (human)
CTD
RGD
PMID:24590895 PMID:25151357 PMID:29365412 RGD:151347630 RGD:151347646 NCBI chrNW_004936554:2,872,729...2,996,821
Ensembl chrNW_004936554:2,872,713...2,996,823
JBrowse link
G Fat2 FAT atypical cadherin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chrNW_004936515:11,132,059...11,200,544
Ensembl chrNW_004936515:11,132,059...11,199,153
JBrowse link
G Fat3 FAT atypical cadherin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chrNW_004936674:1,770,884...2,104,909
Ensembl chrNW_004936674:1,775,744...2,374,883
JBrowse link
G Fat4 FAT atypical cadherin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chrNW_004936662:3,537,917...3,704,012
Ensembl chrNW_004936662:3,537,925...3,690,877
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chrNW_004936689:2,261,163...2,449,951
Ensembl chrNW_004936689:2,259,477...2,344,764
JBrowse link
G Fes FES proto-oncogene, tyrosine kinase exacerbates ISO DNA:hypermethylation: (human) RGD PMID:24936140 RGD:153323298 NCBI chrNW_004936483:16,123,938...16,135,044
Ensembl chrNW_004936483:16,123,779...16,135,044
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 treatment ISO RGD PMID:25989802 RGD:150520041 NCBI chrNW_004936597:1,388,394...1,397,731
Ensembl chrNW_004936597:1,385,624...1,397,758
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936485:17,305,376...17,311,797 JBrowse link
G Foxa1 forkhead box A1 onset ISO DNA:SNPs: :rs12894364 C>T, rs2145146 C>A (human) RGD PMID:27050876 PMID:29788741 RGD:151665743 RGD:151665759 NCBI chrNW_004936494:11,529,546...11,535,224
Ensembl chrNW_004936494:11,529,546...11,535,224
JBrowse link
G Fubp1 far upstream element binding protein 1 exacerbates ISO mRNA:increased expression:esophagus (human)
protein:increased expression:esophagus (human)
RGD PMID:26490982 PMID:32481602 RGD:151361192 RGD:151361197 NCBI chrNW_004936571:4,729,135...4,760,943
Ensembl chrNW_004936571:4,732,581...4,760,942
JBrowse link
G Gdi2 GDP dissociation inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936484:8,748,050...8,775,234
Ensembl chrNW_004936484:8,747,984...8,779,236
JBrowse link
G Glo1 glyoxalase I ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936476:20,910,696...20,928,583
Ensembl chrNW_004936476:20,910,629...20,930,295
JBrowse link
G Gpx3 glutathione peroxidase 3 disease_progression ISO DNA:hypermethylation RGD PMID:25050929 PMID:30018730 RGD:151665494 RGD:151665741 NCBI chrNW_004936647:3,904,787...3,914,223
Ensembl chrNW_004936647:3,906,113...3,913,498
JBrowse link
G Grb7 growth factor receptor bound protein 7 exacerbates ISO protein:increased expression:esophagus (human)
mRNA:increased expression:esophagus mucosa (human)
RGD PMID:10797316 PMID:26465158 RGD:151347654 RGD:151347661 NCBI chrNW_004936490:14,912,010...14,925,380
Ensembl chrNW_004936490:14,917,372...14,925,337
JBrowse link
G Gsto1 glutathione S-transferase omega 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936600:1,932,152...1,943,342
Ensembl chrNW_004936600:1,930,695...1,943,422
JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO DNA:polymorphism: :p.I105V (human) RGD PMID:17916905 RGD:14700982 NCBI chrNW_004936599:2,197,681...2,200,642
Ensembl chrNW_004936599:2,197,634...2,201,050
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:17201171 NCBI chrNW_004936495:5,770,988...5,816,157
Ensembl chrNW_004936495:5,770,669...5,816,157
JBrowse link
G Hmgb1 high mobility group box 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936472:25,236,728...25,246,585
Ensembl chrNW_004936472:25,236,728...25,246,580
JBrowse link
G Hmgn5 high mobility group nucleosome binding domain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28914995 NCBI chrNW_004936547:2,607,491...2,614,037 JBrowse link
G Hoxb7 homeobox B7 severity ISO protein:increased expression:esophageal mucosa (human) RGD PMID:26076456 RGD:10402177 NCBI chrNW_004936490:12,777,005...12,780,515
Ensembl chrNW_004936490:12,777,020...12,780,522
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936487:13,348,465...13,352,717
Ensembl chrNW_004936487:13,348,465...13,352,717
JBrowse link
G Htra1 HtrA serine peptidase 1 exacerbates
ameliorates
ISO mRNA,protein:decreased expression:epithelium of esophagus (human)
human gene and cells in mouse model
RGD PMID:23079781 RGD:152975633 NCBI chrNW_004936486:11,271,130...11,317,271
Ensembl chrNW_004936486:11,271,130...11,316,739
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO human cells in mouse model RGD PMID:32367071 RGD:149735568 NCBI chrNW_004936483:15,845,777...15,864,341
Ensembl chrNW_004936483:15,845,792...15,864,341
JBrowse link
G Jak2 Janus kinase 2 severity ISO protein:increased phosphorylation:esophagus squamous epithelium (human) RGD PMID:32158193 RGD:127285669 NCBI chrNW_004936503:111,722...243,627
Ensembl chrNW_004936503:110,963...241,867
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit exacerbates ISO protein:increased expression:esophagus (human) RGD PMID:19758438 PMID:30227324 RGD:151347669 RGD:151347672 NCBI chrNW_004936659:1,890,786...1,892,619
Ensembl chrNW_004936659:1,891,080...1,892,123
JBrowse link
G Kat2b lysine acetyltransferase 2B ISO mRNA:decreased expression:esophagus (human) RGD PMID:19525977 RGD:9590307 NCBI chrNW_004936473:12,341,545...12,415,637
Ensembl chrNW_004936473:12,344,343...12,417,875
JBrowse link
G Kdm4c lysine demethylase 4C severity
susceptibility
ISO protein:increased expression:esophageal epithelium, nucleus (human)
DNA:snp:intron:IVS8-3292G>A (rs1340513) (human)
RGD PMID:15805246 PMID:24224128 RGD:9587746 RGD:9587752 NCBI chrNW_004936539:1,198,105...1,580,078
Ensembl chrNW_004936539:1,198,147...1,580,082
JBrowse link
G Kdm5b lysine demethylase 5B severity ISO protein:increased expression:esophageal mucosa, cytoplasm (human) RGD PMID:22534467 RGD:9587776 NCBI chrNW_004936567:1,782,056...1,860,861
Ensembl chrNW_004936567:1,781,995...1,863,461
JBrowse link
G Kdm6a lysine demethylase 6A ameliorates ISO DNA:mutations:multiple (human)
mRNA:increased expression:esophagus (human)
protein:increased expression:esophagus (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:25151357 PMID:29351209 PMID:31804468 RGD:150429739 RGD:150429742 RGD:9588233 NCBI chrNW_004936502:10,980,303...11,196,711
Ensembl chrNW_004936502:10,980,118...11,196,163
JBrowse link
G Kmt2c lysine methyltransferase 2C ISO CTD Direct Evidence: marker/mechanism
DNA:mutations:multiple (human)
CTD
RGD
PMID:25151357 RGD:9588233 NCBI chrNW_004936527:7,310,885...7,508,032
Ensembl chrNW_004936527:7,312,721...7,506,365
JBrowse link
G Kmt2d lysine methyltransferase 2D ISO DNA:mutations:multiple (human)
mRNA:increased expression:esophagus
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:25151357 PMID:29532228 RGD:150521712 RGD:9588233 NCBI chrNW_004936512:6,819,240...6,860,852
Ensembl chrNW_004936512:6,822,057...6,854,451
JBrowse link
G Krt13 keratin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936490:16,419,662...16,423,949 JBrowse link
G Krt19 keratin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936490:16,440,723...16,444,679
Ensembl chrNW_004936490:16,440,693...16,444,791
JBrowse link
G Krt7 keratin 7 disease_progression ISO RGD PMID:29788741 RGD:151665759 NCBI chrNW_004936512:9,641,587...9,656,573
Ensembl chrNW_004936512:9,641,587...9,656,524
JBrowse link
G LOC101957714 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial susceptibility ISO DNA:SNP:CDS: (rs2296241) (human) RGD PMID:28362172 RGD:151665500 NCBI chrNW_004936514:1,467,460...1,480,185
Ensembl chrNW_004936514:1,467,261...1,480,185
JBrowse link
G LOC101964975 interleukin-8 severity ISO mRNA:increased expression:esophagus (human) RGD PMID:31423201 RGD:150520019 NCBI chrNW_004936598:1,779,471...1,781,353
Ensembl chrNW_004936598:1,779,471...1,781,353
JBrowse link
G LOC101965998 notch receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chrNW_004936872:454,273...539,544
Ensembl chrNW_004936872:390,852...536,321
JBrowse link
G LOC101969148 cytochrome P450 1A1 ISO RGD PMID:11860825 RGD:14700943 NCBI chrNW_004936471:33,682,730...33,688,332
Ensembl chrNW_004936471:33,682,730...33,688,332
JBrowse link
G LOC101970101 cytochrome P450 1B1 ISO protein:increased expression:esophagus (rat) RGD PMID:18618592 RGD:7829715 NCBI chrNW_004936663:345,021...355,188
Ensembl chrNW_004936663:348,368...355,191
JBrowse link
G LOC101975674 cytochrome P450 26B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chrNW_004936491:16,010,394...16,028,852
Ensembl chrNW_004936491:16,010,070...16,028,895
JBrowse link
G Loxl2 lysyl oxidase like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24716982 NCBI chrNW_004936555:6,781,563...6,865,662
Ensembl chrNW_004936555:6,781,321...6,865,768
JBrowse link
G Lta lymphotoxin alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chrNW_004936727:1,940,081...1,941,022
Ensembl chrNW_004936727:1,940,081...1,941,022
JBrowse link
G Lzts1 leucine zipper tumor suppressor 1 ISO ClinVar Annotator: match by term: Esophageal squamous cell carcinoma, somatic | ClinVar Annotator: match by term: LZTS1-related condition OMIM
ClinVar
PMID:10097140 PMID:25741868 PMID:26504261 PMID:28492532 NCBI chrNW_004936555:4,330,878...4,384,883
Ensembl chrNW_004936555:4,330,787...4,384,932
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18691855 NCBI chrNW_004936662:92,421...98,531
Ensembl chrNW_004936662:92,328...99,517
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 sexual_dimorphism ISO DNA:missense mutation, SNP:CDS, exon 14, 3'-UTR: (rs702689,rs702688) (human) RGD PMID:32753933 RGD:150573717 NCBI chrNW_004936480:11,082,811...11,156,691
Ensembl chrNW_004936480:11,083,605...11,156,691
JBrowse link
G Mbd4 methyl-CpG binding domain 4, DNA glycosylase susceptibility ISO DNA:snp:intron:IVS5-140A>G (rs3138355) (human)
DNA:snp:cds:p.E346K (rs140693) (human)
RGD PMID:15205355 PMID:25162968 RGD:9588976 RGD:9588980 NCBI chrNW_004936602:968,159...980,452
Ensembl chrNW_004936602:956,784...967,884
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase disease_progression ISO CTD Direct Evidence: marker/mechanism
DNA, protein:hypermethylation, decreased expression:promoter, esophagus
CTD
RGD
PMID:21674174 PMID:25520135 RGD:126790574 NCBI chrNW_004936486:16,744,607...16,923,209
Ensembl chrNW_004936486:16,744,570...16,923,543
JBrowse link
G Mlh1 mutL homolog 1 disease_progression ISO DNA, protein:hypermethylation, decreased expression:promoter, esophagus RGD PMID:21674174 RGD:126790574 NCBI chrNW_004936473:26,556,636...26,600,830
Ensembl chrNW_004936473:26,556,611...26,603,736
JBrowse link
G Mmp14 matrix metallopeptidase 14 ISO protein:increased expression: esophagus RGD PMID:24789592 RGD:152600903 NCBI chrNW_004936722:1,447,189...1,457,632
Ensembl chrNW_004936722:1,447,335...1,457,611
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO protein:increased activity: esophagus RGD PMID:24789592 RGD:152600903 NCBI chrNW_004936475:7,801,356...7,825,831
Ensembl chrNW_004936475:7,801,277...7,825,851
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO protein:increased activity: esophagus RGD PMID:24789592 RGD:152600903 NCBI chrNW_004936514:7,038,240...7,045,873
Ensembl chrNW_004936514:7,037,639...7,045,793
JBrowse link
G Msh2 mutS homolog 2 disease_progression ISO DNA, protein:hypermethylation, decreased expression:promoter, esophagus
DNA, protein:hypermethylation, decreased expression:esophagus
RGD PMID:21674174 PMID:22265839 PMID:24366688 RGD:126790560 RGD:126790573 RGD:126790574 NCBI chrNW_004936508:4,943,987...5,013,356
Ensembl chrNW_004936508:4,944,007...5,013,356
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chrNW_004936509:6,589,967...6,621,171
Ensembl chrNW_004936509:6,590,630...6,620,262
JBrowse link
G Notch1 notch receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chrNW_004936669:1,292,016...1,334,061
Ensembl chrNW_004936669:1,292,088...1,332,428
JBrowse link
G Notch3 notch receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chrNW_004936596:5,265,984...5,301,430
Ensembl chrNW_004936596:5,265,999...5,300,429
JBrowse link
G Pagr1 PAXIP1 associated glutamate rich protein 1 ISO mRNA, protein:decreased expression:esophagus (human) RGD PMID:33833989 RGD:153344568 NCBI chrNW_004936501:12,657,092...12,660,106
Ensembl chrNW_004936501:12,656,435...12,660,067
JBrowse link
G Pbx3 PBX homeobox 3 ISO RNA:increased expression:esophagus squamous epithelium (human) RGD PMID:32449803 RGD:153345544 NCBI chrNW_004936487:13,779,999...13,986,617
Ensembl chrNW_004936487:13,779,454...13,987,722
JBrowse link
G Pfn1 profilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936677:2,762,971...2,766,038
Ensembl chrNW_004936677:2,762,971...2,766,149
JBrowse link
G Plce1 phospholipase C epsilon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20729852 PMID:20729853 NCBI chrNW_004936601:817,151...1,105,824
Ensembl chrNW_004936601:816,190...1,105,830
JBrowse link
G Prdx1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936474:26,641,776...26,653,291
Ensembl chrNW_004936474:26,639,259...26,653,328
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 disease_progression ISO RGD PMID:19492245 RGD:6482249 NCBI chrNW_004936476:25,894,313...25,899,132
Ensembl chrNW_004936476:25,894,027...25,899,319
JBrowse link
G Psme1 proteasome activator subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936722:405,491...408,277
Ensembl chrNW_004936722:403,112...408,473
JBrowse link
G Psme2 proteasome activator subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936722:398,406...401,987
Ensembl chrNW_004936722:397,876...402,167
JBrowse link
G Ptch1 patched 1 disease_progression ISO RGD PMID:16475698 RGD:150523841 NCBI chrNW_004936626:4,241,993...4,301,919
Ensembl chrNW_004936626:4,241,908...4,309,476
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15756444 PMID:16543248 PMID:18197933 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
G Ptprt protein tyrosine phosphatase receptor type T susceptibility ISO DNA:SNPs:3'utr: (rs2866943 , rs6029959 ) (human) RGD PMID:25967969 RGD:150520191 NCBI chrNW_004936530:3,555,070...4,327,558
Ensembl chrNW_004936530:3,555,103...4,319,704
JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chrNW_004936565:1,596,227...1,746,706
Ensembl chrNW_004936565:1,597,593...1,746,846
JBrowse link
G Rictor RPTOR independent companion of MTOR complex 2 disease_progression
severity
ISO human cells in mouse model
protein:increased expression:esophagus (human)
RGD PMID:28132115 PMID:30119206 PMID:32642408 RGD:152995460 RGD:152995470 RGD:152995512 NCBI chrNW_004936518:3,198,312...3,314,393
Ensembl chrNW_004936518:3,198,337...3,310,000
JBrowse link
G Rnf6 ring finger protein 6 ISO ClinVar Annotator: match by term: Esophageal squamous cell carcinoma, somatic ClinVar
OMIM
PMID:12154016 NCBI chrNW_004936948:57,806...67,875
Ensembl chrNW_004936948:55,699...67,972
JBrowse link
G Runx2 RUNX family transcription factor 2 ISO mRNA:increased expression:esophagus mucosa RGD PMID:18500170 RGD:126779568 NCBI chrNW_004936476:14,695,965...14,818,246
Ensembl chrNW_004936476:14,695,965...14,905,157
JBrowse link
G Runx3 RUNX family transcription factor 3 disease_progression ISO mRNA:decreased expression:esophagus mucosa RGD PMID:18500170 RGD:126779568 NCBI chrNW_004936474:9,751,946...9,802,910
Ensembl chrNW_004936474:9,751,946...9,802,910
JBrowse link
G Sall4 spalt like transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chrNW_004936514:3,285,778...3,302,179
Ensembl chrNW_004936514:3,285,531...3,303,644
JBrowse link
G Setd5 SET domain containing 5 disease_progression ISO RGD PMID:31981592 RGD:155804254 NCBI chrNW_004936602:3,577,543...3,654,179
Ensembl chrNW_004936602:3,577,525...3,654,269
JBrowse link
G Sfn stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936474:11,274,927...11,279,427
Ensembl chrNW_004936474:11,246,534...11,279,433
JBrowse link
G Slc16a10 solute carrier family 16 member 10 ISO protein:increased expression:esophagus RGD PMID:33609949 RGD:151361149 NCBI chrNW_004936564:6,823,054...6,925,702
Ensembl chrNW_004936564:6,822,992...6,925,849
JBrowse link
G Slc1a5 solute carrier family 1 member 5 disease_progression ISO protein:increased expression:esophagus RGD PMID:26936531 PMID:33609949 RGD:11532833 RGD:151361149 NCBI chrNW_004936664:599,012...610,689
Ensembl chrNW_004936664:598,468...610,698
JBrowse link
G Slc39a6 solute carrier family 39 member 6 ISO CTD Direct Evidence: therapeutic CTD PMID:23644492 NCBI chrNW_004936517:9,166,989...9,188,114
Ensembl chrNW_004936517:9,167,334...9,189,345
JBrowse link
G Slc52a3 solute carrier family 52 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20729853 NCBI chrNW_004936485:17,771,797...17,777,637 JBrowse link
G Slc7a5 solute carrier family 7 member 5 disease_progression ISO protein:increased expression:esophagus RGD PMID:26936531 PMID:31726270 PMID:33609949 RGD:11532833 RGD:151361144 RGD:151361149 NCBI chrNW_004936641:1,513,110...1,538,955 JBrowse link
G Socs1 suppressor of cytokine signaling 1 severity
treatment
ISO mRNA:decreased expression:esophagus RGD PMID:21385099 PMID:28233302 PMID:31728180 RGD:150573691 RGD:150573812 RGD:150573815 NCBI chrNW_004936530:9,312,965...9,315,593
Ensembl chrNW_004936530:9,312,965...9,316,165
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18167182 PMID:21517111 NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781
JBrowse link
G Sox2 SRY-box transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19801978 NCBI chrNW_004936566:1,630,698...1,632,607
Ensembl chrNW_004936566:1,631,822...1,632,613
JBrowse link
G Spen spen family transcriptional repressor ISO associated with Neoplasm Metastasis; DNA:mutations RGD PMID:33363385 RGD:151347445 NCBI chrNW_004936474:3,473,892...3,535,307
Ensembl chrNW_004936474:3,473,901...3,534,628
JBrowse link
G Stim1 stromal interaction molecule 1 exacerbates ISO protein:increased expression:esophagus (human) RGD PMID:31843504 RGD:152995393 NCBI chrNW_004936498:849,775...1,063,552
Ensembl chrNW_004936498:849,739...1,063,552
JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25129146 NCBI chrNW_004936531:8,555,966...8,562,829
Ensembl chrNW_004936531:8,555,637...8,562,885
JBrowse link
G Tagln transgelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936542:2,445,825...2,451,216
Ensembl chrNW_004936542:2,445,659...2,451,216
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member ISO protein:decreased expression:esophagus RGD PMID:19492245 RGD:6482249 NCBI chrNW_004936476:25,899,514...25,907,690
Ensembl chrNW_004936476:25,899,339...25,907,695
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member ISO protein:decreased expression:esophagus RGD PMID:19492245 RGD:6482249 NCBI chrNW_004936476:25,913,699...25,923,419
Ensembl chrNW_004936476:25,913,663...25,923,427
JBrowse link
G Tcn2 transcobalamin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chrNW_004936904:97,535...113,886
Ensembl chrNW_004936904:95,542...113,985
JBrowse link
G Tert telomerase reverse transcriptase susceptibility
no_association
ISO DNA:SNPs: : rs2853691,rs2736100(human)
mRNA:increased expression:esophagus squamous epithelium:
DNA:SNP: :rs2736098(human)
RGD PMID:15112252 PMID:25007268 PMID:26716642 RGD:11572962 RGD:150530488 RGD:152977757 NCBI chrNW_004936815:468,987...492,666
Ensembl chrNW_004936815:469,020...491,697
JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 severity ISO DNA:mutations
associated with Lymphatic Metastasis;mRNA:decreased expression:esophagus squamous epithelium (human)
RGD PMID:26093090 PMID:26873401 PMID:27050164 RGD:11528815 RGD:150429656 RGD:150429668 NCBI chrNW_004936752:440,137...577,339
Ensembl chrNW_004936752:440,136...577,615
JBrowse link
G Tet3 tet methylcytosine dioxygenase 3 ISO mRNA:decreased expression:esophagus squamous epithelium (human) RGD PMID:27050164 RGD:150429668 NCBI chrNW_004936556:292,551...391,644
Ensembl chrNW_004936556:292,586...385,741
JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 ISO OMIM NCBI chrNW_004936473:21,324,669...21,409,430
Ensembl chrNW_004936473:21,324,658...21,409,430
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 severity ISO mRNA,protein:increased expression:esophagus squamous epithelium (human) RGD PMID:28197630 RGD:151347617 NCBI chrNW_004936560:5,124,955...5,138,988
Ensembl chrNW_004936560:5,128,843...5,138,345
JBrowse link
G Tnfaip8 TNF alpha induced protein 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21969086 NCBI chrNW_004936715:2,205,977...2,322,835
Ensembl chrNW_004936715:2,205,977...2,322,854
JBrowse link
G Tnxb tenascin XB ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chrNW_004936727:1,492,725...1,550,762
Ensembl chrNW_004936727:1,500,200...1,550,564
JBrowse link
G Tp53 tumor protein p53 ISO DNA:misssense mutation: :p.R72P (rs1042522) (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16543248 PMID:25151357 PMID:28789369 RGD:14995932 NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425
JBrowse link
G Tpi1 triosephosphate isomerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936709:948,151...951,430
Ensembl chrNW_004936709:945,201...951,441
JBrowse link
G Tpm1 tropomyosin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936471:23,643,645...23,670,775
Ensembl chrNW_004936471:23,643,613...23,670,775
JBrowse link
G Tpm2 tropomyosin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936524:3,679,719...3,687,828
Ensembl chrNW_004936524:3,679,560...3,688,308
JBrowse link
G Txndc17 thioredoxin domain containing 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chrNW_004936677:1,352,233...1,354,576
Ensembl chrNW_004936677:1,352,240...1,355,075
JBrowse link
G Tymp thymidine phosphorylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11641616 NCBI chrNW_004936629:315,609...320,356
Ensembl chrNW_004936629:315,610...319,076
JBrowse link
G Usp8 ubiquitin specific peptidase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35022897 NCBI chrNW_004936471:12,463,189...12,524,148
Ensembl chrNW_004936471:12,463,120...12,520,674
JBrowse link
G Ventx VENT homeobox ISO CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chrNW_004936486:19,434,362...19,436,025 JBrowse link
G Wrap53 WD repeat containing antisense to TP53 disease_progression ISO RGD PMID:24626331 RGD:21081532 NCBI chrNW_004936595:936,184...952,784
Ensembl chrNW_004936595:936,487...952,791
JBrowse link
G Wwox WW domain containing oxidoreductase ISO ClinVar Annotator: match by term: Esophageal squamous cell carcinoma, somatic ClinVar
OMIM
PMID:11956080 PMID:28492532 NCBI chrNW_004936475:26,342,245...27,209,563
Ensembl chrNW_004936475:26,342,220...27,208,711
JBrowse link
G Xpo1 exportin 1 exacerbates ISO protein:increased expression:esophagus (human)
mRNA, protein:increased expression:epithelium of esophagus (human)
RGD PMID:24898882 PMID:25148895 RGD:151667431 RGD:151667436 NCBI chrNW_004936491:6,921,753...6,962,062
Ensembl chrNW_004936491:6,921,319...6,962,343
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 no_association
susceptibility
treatment
ISO CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds: p.R399Q (human)
DNA:SNPs,haplotypes:multiple (human)
DNA:SNPs:exon 6, exon 9, exon 10:multiple (human)
CTD
RGD
PMID:11400117 PMID:16639733 PMID:25710005 PMID:27123143 PMID:28356949 RGD:150530501 RGD:150530505 RGD:150530634 RGD:151347444 NCBI chrNW_004936706:752,571...783,746
Ensembl chrNW_004936706:751,108...783,777
JBrowse link
G Zcchc12 zinc finger CCHC-type containing 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chrNW_004936479:11,021,502...11,024,612 JBrowse link
Familial Cystic Parathyroid Adenomatosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc73 cell division cycle 73 ISO ClinVar Annotator: match by term: Cystic parathyroid adenoma ClinVar PMID:12434154 NCBI chrNW_004936638:1,365,457...1,482,497
Ensembl chrNW_004936638:1,365,648...1,483,277
JBrowse link
familial medullary thyroid carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Insrr insulin receptor related receptor ISO ClinVar Annotator: match by term: Familial medullary thyroid carcinoma | ClinVar Annotator: match by term: Thyroid cancer, familial medullary ClinVar NCBI chrNW_004936580:5,982,259...5,999,994
Ensembl chrNW_004936580:5,983,006...5,999,994
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO ClinVar Annotator: match by term: Familial medullary thyroid carcinoma | ClinVar Annotator: match by term: Thyroid cancer, familial medullary ClinVar PMID:10330344 PMID:10443680 PMID:10861667 PMID:11139246 PMID:11159935 More... NCBI chrNW_004936580:6,002,168...6,021,690
Ensembl chrNW_004936580:6,002,120...6,021,709
JBrowse link
G Prlr prolactin receptor ISO OMIM:155240 MouseDO NCBI chrNW_004936518:6,352,133...6,495,242
Ensembl chrNW_004936518:6,473,536...6,487,757
JBrowse link
G Ret ret proto-oncogene susceptibility ISO ClinVar Annotator: match by term: Familial medullary thyroid carcinoma | ClinVar Annotator: match by term: Thyroid cancer, familial medullary ClinVar
OMIM
PMID:2660074 PMID:3078962 PMID:3697657 PMID:7536460 PMID:7595170 More... NCBI chrNW_004936617:2,927,185...2,980,594
Ensembl chrNW_004936617:2,927,155...2,980,602
JBrowse link
Follicular Thyroid Cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 ClinVar PMID:12068308 PMID:12198537 PMID:12960123 PMID:14679157 PMID:15035987 More... NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664
JBrowse link
G Cbx7 chromobox 7 ISO protein:decreased expression:thyroid gland: RGD PMID:18701502 RGD:9587357 NCBI chrNW_004936492:2,411,171...2,428,484
Ensembl chrNW_004936492:2,410,308...2,428,682
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:10566621 NCBI chrNW_004936510:4,679,349...4,696,511
Ensembl chrNW_004936510:4,679,321...4,696,529
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: THYROID CANCER, NONMEDULLARY, 2 | ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 OMIM
ClinVar
PMID:12727991 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 More... NCBI chrNW_004936888:375,372...378,125
Ensembl chrNW_004936888:375,377...377,958
JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: THYROID CANCER, NONMEDULLARY, 2 | ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 ClinVar PMID:12727991 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 More... NCBI chrNW_004936888:379,622...397,647
Ensembl chrNW_004936888:382,062...402,083
JBrowse link
G Minpp1 multiple inositol-polyphosphate phosphatase 1 ISO ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 OMIM
ClinVar
PMID:11297621 NCBI chrNW_004936735:1,585,741...1,627,910
Ensembl chrNW_004936735:1,586,446...1,627,845
JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 OMIM
ClinVar
PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chrNW_004936627:73,413...82,590
Ensembl chrNW_004936627:73,413...82,590
JBrowse link
G Pax8 paired box 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15785241 NCBI chrNW_004936783:1,523,658...1,553,464
Ensembl chrNW_004936783:1,523,661...1,576,568
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:15785241 NCBI chrNW_004936602:1,230,907...1,368,588
Ensembl chrNW_004936602:1,230,907...1,304,743
JBrowse link
G Pten phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 ClinVar NCBI chrNW_004936735:1,252,414...1,338,318
Ensembl chrNW_004936735:1,252,414...1,338,323
JBrowse link
G Srgap1 SLIT-ROBO Rho GTPase activating protein 1 ISO ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 OMIM
ClinVar
PMID:23539728 PMID:25741868 PMID:28492532 NCBI chrNW_004936545:2,277,449...2,557,330
Ensembl chrNW_004936545:2,278,290...2,552,552
JBrowse link
glottis squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wrap53 WD repeat containing antisense to TP53 disease_progression ISO RGD PMID:28849066 RGD:21081521 NCBI chrNW_004936595:936,184...952,784
Ensembl chrNW_004936595:936,487...952,791
JBrowse link
head and neck cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccng1 cyclin G1 ISO mRNA:decreased expression:head and neck (human) RGD PMID:27982046 RGD:151361200 NCBI chrNW_004936515:614,287...621,213
Ensembl chrNW_004936515:614,290...619,963
JBrowse link
G Ccng2 cyclin G2 ISO mRNA:decreased expression:head and neck (human) RGD PMID:27982046 RGD:151361200 NCBI chrNW_004936676:1,026,113...1,035,313
Ensembl chrNW_004936676:1,025,856...1,037,698
JBrowse link
G Dcdc1 doublecortin domain containing 1 ISO ClinVar Annotator: match by term: Head and neck cancer ClinVar PMID:25741868 PMID:28492532 PMID:32266149 NCBI chrNW_004936533:6,559,484...6,827,979 JBrowse link
G Egfr epidermal growth factor receptor ISO ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:18089823 PMID:18355544 PMID:21172876 PMID:21274259 PMID:23380224 More... NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:7668257 PMID:7719344 PMID:8651276 PMID:9677057 PMID:9700203 More... NCBI chrNW_004936486:10,506,680...10,606,272
Ensembl chrNW_004936486:10,507,097...10,602,019
JBrowse link
G Kdm4c lysine demethylase 4C susceptibility ISO DNA:snps:cds, intron:p.N396D (rs2296067), IVS10G>T (rs818912) (human) RGD PMID:19339270 RGD:9587748 NCBI chrNW_004936539:1,198,105...1,580,078
Ensembl chrNW_004936539:1,198,147...1,580,082
JBrowse link
G LOC101964975 interleukin-8 exacerbates ISO mRNA:increased expression:head, neck (human) RGD PMID:31452775 RGD:150520018 NCBI chrNW_004936598:1,779,471...1,781,353
Ensembl chrNW_004936598:1,779,471...1,781,353
JBrowse link
G LOC101969148 cytochrome P450 1A1 ISO DNA:hypermethylation RGD PMID:16721740 PMID:20846153 RGD:14700957 RGD:14700978 NCBI chrNW_004936471:33,682,730...33,688,332
Ensembl chrNW_004936471:33,682,730...33,688,332
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:15016963 PMID:15254419 PMID:15647370 PMID:15805248 PMID:16906227 More... NCBI chrNW_004936566:3,924,013...3,951,052
Ensembl chrNW_004936566:3,923,934...3,951,073
JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein ISO ClinVar Annotator: match by term: Head and neck cancer ClinVar PMID:32266149 NCBI chrNW_004936677:2,575,255...2,585,969
Ensembl chrNW_004936677:2,579,010...2,586,002
JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:9067756 PMID:11370630 PMID:11782540 PMID:16818505 PMID:17606709 More... NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425
JBrowse link
head and neck squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chrNW_004936501:3,400,971...3,467,061
Ensembl chrNW_004936501:3,401,285...3,470,460
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chrNW_004936636:292,631...341,999
Ensembl chrNW_004936636:292,709...340,393
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:11569495 PMID:11853795 PMID:12399961 PMID:12623848 PMID:14745431 More... NCBI chrNW_004936487:17,690,206...17,819,619
Ensembl chrNW_004936487:17,690,968...17,819,669
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Head and neck squamous cell carcinoma ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093
JBrowse link
G Ankrd17 ankyrin repeat domain 17 ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:28580594 NCBI chrNW_004936598:2,191,604...2,338,832
Ensembl chrNW_004936598:2,191,735...2,340,453
JBrowse link
G Atp7b ATPase copper transporting beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:12509969 NCBI chrNW_004936565:4,694,294...4,763,661
Ensembl chrNW_004936565:4,694,281...4,763,773
JBrowse link
G B2m beta-2-microglobulin ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:26619011 NCBI chrNW_004936471:7,646,504...7,655,656
Ensembl chrNW_004936471:7,646,373...7,655,778
JBrowse link
G Birc2 baculoviral IAP repeat containing 2 exacerbates ISO mRNA:increased expression:head or neck skin (human) RGD PMID:31964418 RGD:153344516 NCBI chrNW_004936551:5,515,904...5,535,864 JBrowse link
G Birc3 baculoviral IAP repeat containing 3 ameliorates ISO mRNA:increased expression:head or neck skin (human) RGD PMID:31964418 RGD:153344516 NCBI chrNW_004936551:5,544,047...5,556,550
Ensembl chrNW_004936551:5,544,065...5,556,555
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma | ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664
JBrowse link
G Casp8 caspase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23358896 NCBI chrNW_004936726:554,627...596,334
Ensembl chrNW_004936726:554,758...595,922
JBrowse link
G Ccdc3 coiled-coil domain containing 3 ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:26614431 NCBI chrNW_004936484:2,455,819...2,567,467
Ensembl chrNW_004936484:2,455,819...2,568,682
JBrowse link
G Ccna1 cyclin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23358896 PMID:29464035 NCBI chrNW_004936472:30,574,957...30,586,596
Ensembl chrNW_004936472:30,573,812...30,586,559
JBrowse link
G Ccna2 cyclin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chrNW_004936662:1,073,460...1,079,136
Ensembl chrNW_004936662:1,073,920...1,079,136
JBrowse link
G Ccnb1 cyclin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chrNW_004936480:400,287...407,677
Ensembl chrNW_004936480:399,224...407,704
JBrowse link
G Ccnd1 cyclin D1 disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:9796972 PMID:26909611 PMID:29464035 RGD:13434911 Ensembl chrNW_004936599:973,838...983,316 JBrowse link
G Ccne1 cyclin E1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chrNW_004936570:5,536,817...5,547,880
Ensembl chrNW_004936570:5,536,672...5,548,008
JBrowse link
G Ccne2 cyclin E2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chrNW_004936544:7,839,730...7,852,251
Ensembl chrNW_004936544:7,839,113...7,851,335
JBrowse link
G Cdc73 cell division cycle 73 exacerbates ISO protein:increased expression:squamous epithelium (human) RGD PMID:26124004 RGD:11065919 NCBI chrNW_004936638:1,365,457...1,482,497
Ensembl chrNW_004936638:1,365,648...1,483,277
JBrowse link
G Cdk2 cyclin dependent kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chrNW_004936646:379,849...385,648
Ensembl chrNW_004936646:379,842...385,877
JBrowse link
G Cdk4 cyclin dependent kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chrNW_004936646:1,886,262...1,889,260 JBrowse link
G Cdk6 cyclin dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chrNW_004936803:1,025,047...1,229,396
Ensembl chrNW_004936803:1,024,779...1,227,516
JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 ISO mRNA:increased expression:head or neck skin (human) RGD PMID:28486105 RGD:153323299 NCBI chrNW_004936709:1,183,243...1,214,144
Ensembl chrNW_004936709:1,183,254...1,214,149
JBrowse link
G Cldn1 claudin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33665778 NCBI chrNW_004936578:98,489...113,125
Ensembl chrNW_004936578:98,273...113,153
JBrowse link
G Cntn4 contactin 4 ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:28595731 NCBI chrNW_004936577:2,298,648...2,768,864
Ensembl chrNW_004936577:2,355,237...2,770,349
JBrowse link
G Crebbp CREB binding protein ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 More... NCBI chrNW_004936694:552,447...663,237
Ensembl chrNW_004936694:553,753...663,617
JBrowse link
G Ctnnb1 catenin beta 1 ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:9927029 PMID:10192393 PMID:23265383 PMID:25157968 PMID:26619011 More... NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 severity ISO RGD PMID:24556606 RGD:150429746 NCBI chrNW_004936831:799,948...946,139
Ensembl chrNW_004936831:865,965...946,139
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta susceptibility ISO DNA:SNP,haplotype:promoter:-149C>T,-579G>T(human) RGD PMID:18455294 RGD:9589078 NCBI chrNW_004936485:19,547,836...19,570,716 JBrowse link
G Dpyd dihydropyrimidine dehydrogenase ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar NCBI chrNW_004936537:1,660,461...2,439,305
Ensembl chrNW_004936537:1,660,477...2,439,273
JBrowse link
G Egfr epidermal growth factor receptor ISO ClinVar Annotator: match by term: Head and neck squamous cell carcinoma | ClinVar Annotator: match by term: Lip and oral cavity carcinoma | ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:15118073 PMID:15118125 PMID:15788655 PMID:17177598 PMID:20415598 More... NCBI chrNW_004936678:365,005...560,546
Ensembl chrNW_004936678:365,834...436,528
JBrowse link
G Ep300 E1A binding protein p300 ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:26619011 NCBI chrNW_004936492:696,982...778,132
Ensembl chrNW_004936492:696,960...778,138
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO ClinVar Annotator: match by term: Head and neck squamous cell carcinoma RGD
ClinVar
PMID:20604875 PMID:22908275 PMID:26619011 RGD:126790467 NCBI chrNW_004936490:14,887,062...14,910,038
Ensembl chrNW_004936490:14,887,043...14,909,956
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 severity ISO RGD PMID:20604875 RGD:126790467 NCBI chrNW_004936586:4,065,767...5,100,690
Ensembl chrNW_004936586:4,066,498...5,100,035
JBrowse link
G Fancb FA complementation group B ISO DNA:hypermethylation:promoter RGD PMID:20332657 RGD:11344903 NCBI chrNW_004936470:4,305,220...4,323,456
Ensembl chrNW_004936470:4,305,740...4,323,374
JBrowse link
G Fancd2 FA complementation group D2 ISO RGD PMID:20935219 RGD:11344907 NCBI chrNW_004936602:3,162,177...3,220,468
Ensembl chrNW_004936602:3,161,960...3,209,868
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:25741868 PMID:26619011 NCBI chrNW_004936689:2,261,163...2,449,951
Ensembl chrNW_004936689:2,259,477...2,344,764
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Head and neck squamous cell carcinoma ClinVar PMID:1908846 PMID:7773297 PMID:8589699 PMID:8640234 PMID:8858131 More... NCBI chrNW_004936477:21,591,772...21,606,289
Ensembl chrNW_004936477:21,591,792...21,606,296
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 severity ISO DNA:SNP:exon 9: p.G388R (human) RGD PMID:17084840 RGD:150520023 NCBI chrNW_004936597:1,388,394...1,397,731
Ensembl chrNW_004936597:1,385,624...1,397,758
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:28580594 NCBI chrNW_004936473:397,140...1,424,805
Ensembl chrNW_004936473:676,237...1,424,506
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:26614431 NCBI chrNW_004936651:2,756,559...3,401,806
Ensembl chrNW_004936651:2,762,380...3,401,808
JBrowse link
G Hoxa5 homeobox A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22227861 NCBI chrNW_004936478:3,768,757...3,771,850
Ensembl chrNW_004936478:3,769,258...3,771,840
JBrowse link
G Hoxd10 homeobox D10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22227861 NCBI chrNW_004936509:5,603,661...5,606,850
Ensembl chrNW_004936509:5,603,642...5,606,850
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Head and neck squamous cell carcinoma | ClinVar Annotator: match by term: Lip and oral cavity carcinoma | ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:1904555 PMID:2105486 PMID:3510078 PMID:11150980 PMID:12727991 More... NCBI chrNW_004936888:375,372...378,125
Ensembl chrNW_004936888:375,377...377,958
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:20171147 PMID:20847235 PMID:20946881 PMID:21647154 PMID:21889589 More... NCBI chrNW_004936483:15,845,777...15,864,341
Ensembl chrNW_004936483:15,845,792...15,864,341
JBrowse link
G Igf1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30594912 NCBI chrNW_004936492:11,709,623...11,784,028
Ensembl chrNW_004936492:11,709,222...11,778,351
JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27738319 NCBI chrNW_004936783:1,210,715...1,218,315
Ensembl chrNW_004936783:1,210,809...1,218,315
JBrowse link
G Il1rap interleukin 1 receptor accessory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27738319 NCBI chrNW_004937049:48,267...185,766
Ensembl chrNW_004937049:48,274...181,281
JBrowse link
G Il2 interleukin 2 ISO RGD PMID:2787951 PMID:3263896 RGD:8662923 RGD:8662971 NCBI chrNW_004936662:1,594,953...1,599,625
Ensembl chrNW_004936662:1,594,953...1,599,625
JBrowse link
G Ing1 inhibitor of growth family member 1 ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck OMIM
ClinVar
PMID:10866301 NCBI chrNW_004936472:2,132,991...2,140,343 JBrowse link
G Irs1 insulin receptor substrate 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30594912 NCBI chrNW_004936525:9,064,442...9,125,972
Ensembl chrNW_004936525:9,064,466...9,122,635
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit ameliorates ISO human cell line in a mouse model RGD PMID:26754630 RGD:11556098 NCBI chrNW_004936659:1,890,786...1,892,619
Ensembl chrNW_004936659:1,891,080...1,892,123
JBrowse link
G Keap1 kelch like ECH associated protein 1