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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Head and Neck Neoplasms
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Accession:DOID:9006169 term browser browse the term
Definition:Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
Synonyms:exact_synonym: Head Neoplasms;   Head, Neck Neoplasms;   Neck Neoplasms;   UADT Neoplasm;   UADT Neoplasms;   Upper Aerodigestive Tract Neoplasms;   upper aerodigestive tract neoplasm
 narrow_synonym: Cancer of Head;   Cancer of Neck;   Cancer of the Head;   Cancer of the Neck;   Head Cancer;   Neck Cancer
 primary_id: MESH:D006258
 alt_id: RDO:0000780
 xref: EFO:0004284;   EFO:0005950



show annotations for term's descendants           Sort by:
Head and Neck Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOBEC3B apolipoprotein B mRNA editing enzyme catalytic subunit 3B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23852168 NCBI chr 5:9,098,676...9,115,965
Ensembl chr 5:9,097,719...9,116,369
JBrowse link
G AREG amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chr 8:70,417,935...70,428,106
Ensembl chr 8:70,417,923...70,428,102
JBrowse link
G BAP1 BRCA1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr13:34,544,570...34,553,538
Ensembl chr13:34,544,581...34,553,483
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:18566236 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G BCL2L1 BCL2 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18566236 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:17510391 NCBI chr 6:43,083,200...43,085,884
Ensembl chr 6:43,083,207...43,085,836
JBrowse link
G CSF3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:7692001 NCBI chr12:22,333,445...22,335,949
Ensembl chr12:22,333,449...22,338,753
JBrowse link
G DPYD dihydropyrimidine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19020767 NCBI chr 4:119,931,471...120,712,461
Ensembl chr 4:119,931,414...120,712,459
JBrowse link
G EGFR epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12942316 PMID:15342401 PMID:16467544 PMID:23917044 RGD:5131641 NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit severity ISO mRNA:increased expression: : RGD PMID:26659720 RGD:11573297 NCBI chr 6:51,734,318...51,757,508
Ensembl chr 6:51,734,320...51,757,553
JBrowse link
G FAT1 FAT atypical cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23354438 NCBI chr17:8,466,099...8,580,715
Ensembl chr17:8,457,187...8,580,715
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Head and Neck Neoplasms ClinVar PMID:7668257 PMID:7719344 PMID:8651276 PMID:9677057 PMID:9700203 More... NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425
JBrowse link
G GPX1 glutathione peroxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15557674 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433
JBrowse link
G GRP gastrin releasing peptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chr 1:161,708,815...161,721,986
Ensembl chr 1:161,708,812...161,721,782
JBrowse link
G MAL mal, T cell differentiation protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19445022 NCBI chr 3:46,223,610...46,242,306
Ensembl chr 3:46,181,555...46,242,047
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
JBrowse link
G MMP1 matrix metallopeptidase 1 ISO DNA:insertion:promoter:g.-1607insG (human) RGD PMID:19843588 RGD:7207056 NCBI chr 9:33,411,738...33,420,205
Ensembl chr 9:33,411,065...33,420,076
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Head and Neck Neoplasms ClinVar PMID:15016963 PMID:15254419 PMID:15647370 PMID:15805248 PMID:16906227 More... NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,274,587
JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:16179254 NCBI chr14:48,901,097...48,906,855
Ensembl chr14:48,899,343...48,911,231
JBrowse link
G RAD51 RAD51 recombinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22613844 NCBI chr 1:130,592,414...130,640,326
Ensembl chr 1:130,586,665...130,640,136
JBrowse link
G RARB retinoic acid receptor beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17549354 NCBI chr13:12,336,387...12,507,688
Ensembl chr13:12,336,972...12,507,680
JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 ISO mRNA:increased expression:head and neck (human) RGD PMID:21764905 RGD:11039047 NCBI chr12:4,800,578...4,803,767
Ensembl chr12:4,800,624...4,801,675
JBrowse link
G STAT6 signal transducer and activator of transcription 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21765211 NCBI chr 5:22,406,356...22,422,412
Ensembl chr 5:22,406,368...22,421,989
JBrowse link
G TGFA transforming growth factor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15342401 NCBI chr 3:71,948,232...72,054,257
Ensembl chr 3:71,948,137...72,050,474
JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Head and Neck Neoplasms ClinVar PMID:9067756 PMID:11370630 PMID:11782540 PMID:16818505 PMID:17606709 More... NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
G TYMS thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19020767 NCBI chr 6:105,642,730...105,660,279
Ensembl chr 6:105,642,381...105,660,578
JBrowse link
G UROD uroporphyrinogen decarboxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21270338 NCBI chr 6:166,327,243...166,330,558
Ensembl chr 6:166,327,247...166,330,614
JBrowse link
G VEGFA vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16499871 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366
JBrowse link
G XRCC3 X-ray repair cross complementing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22613844
acoustic neuroma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARTN artemin ISO mRNA:increased expression:peripheral nerve: RGD PMID:19937367 RGD:8655552 NCBI chr 6:167,356,363...167,361,370
Ensembl chr 6:167,357,662...167,360,729
JBrowse link
G BDNF brain derived neurotrophic factor ISO mRNA:increased expression:peripheral nerve: RGD PMID:19937367 RGD:8655552 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,624,048...32,679,765
JBrowse link
G CAV1 caveolin 1 ISO RGD PMID:20881564 RGD:8661782 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO mRNA,protein:decreased expression:myelinated nerve: RGD PMID:20600642 RGD:8661792 NCBI chr 7:32,354,776...32,363,771
Ensembl chr 7:32,359,455...32,363,761
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO DNA:snp:promoter:c.-1053C>T (human) RGD PMID:12540498 RGD:1358568 NCBI chr14:141,690,737...141,703,078
Ensembl chr14:141,690,426...141,736,817
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility ISO DNA:missense mutation:cds:p.D312N (rs1799793) (human) RGD PMID:20150366 RGD:5688735 NCBI chr 6:51,734,318...51,757,508
Ensembl chr 6:51,734,320...51,757,553
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 disease_progression ISO RGD PMID:15354013 RGD:11567268 NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,724
JBrowse link
G GDNF glial cell derived neurotrophic factor ISO mRNA:increased expression:peripheral nerve: RGD PMID:19937367 RGD:8655552 NCBI chr16:22,936,602...22,965,929
Ensembl chr16:22,936,604...22,966,536
JBrowse link
G IGF1 insulin like growth factor 1 susceptibility ISO protein:increased expression:serum: RGD PMID:21788435 RGD:8548833 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 susceptibility ISO protein:increased expression:serum: RGD PMID:21788435 RGD:8548833 NCBI chr18:50,002,921...50,009,425
Ensembl chr18:50,003,022...50,010,690
JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor ISO protein:decreased expression:myelinated nerve: RGD PMID:20600642 RGD:8661792 NCBI chr14:46,653,869...46,726,421
Ensembl chr14:46,653,900...46,731,999
JBrowse link
G VEGFA vascular endothelial growth factor A ISO RGD PMID:14660915 RGD:8547959 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366
JBrowse link
adenoid cystic carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,485...42,076,746
JBrowse link
G ARID1A AT-rich interaction domain 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 6:84,049,729...84,124,302
Ensembl chr 6:84,049,087...84,123,349
JBrowse link
G ARID2 AT-rich interaction domain 2 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr 5:76,637,385...76,800,155
Ensembl chr 5:76,636,967...76,797,043
JBrowse link
G ARID4B AT-rich interaction domain 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr14:55,924,333...56,082,209
Ensembl chr14:55,924,367...56,082,198
JBrowse link
G ARID5B AT-rich interaction domain 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr14:65,408,603...65,598,485
Ensembl chr14:65,408,598...65,598,485
JBrowse link
G ASPM assembly factor for spindle microtubules ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr10:19,971,516...20,039,680
Ensembl chr10:19,975,192...20,039,623
JBrowse link
G ATM ATM serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 9:36,620,656...36,759,555
Ensembl chr 9:36,620,658...36,759,552
JBrowse link
G ATR ATR serine/threonine kinase treatment ISO RGD PMID:32001675 RGD:150340693 NCBI chr13:83,175,515...83,289,986
Ensembl chr13:83,174,824...83,289,989
JBrowse link
G ATRX ATRX chromatin remodeler ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr  X:61,584,028...61,872,341
Ensembl chr  X:61,584,848...61,872,287
JBrowse link
G BAP1 BRCA1 associated protein 1 ISO ClinVar Annotator: match by term: Adenocystic carcinoma | ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar PMID:21642991 PMID:24894717 PMID:26166446 PMID:26452128 PMID:28492532 NCBI chr13:34,544,570...34,553,538
Ensembl chr13:34,544,581...34,553,483
JBrowse link
G BCL11A BCL11 transcription factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 3:81,195,217...81,296,165
Ensembl chr 3:81,196,294...81,296,382
JBrowse link
G BCOR BCL6 corepressor ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr  X:35,768,013...35,891,013
Ensembl chr  X:35,768,017...35,814,833
JBrowse link
G BCORL1 BCL6 corepressor like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr  X:106,547,754...106,613,130
Ensembl chr  X:106,549,139...106,612,894
JBrowse link
G BRCA1 BRCA1 DNA repair associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr12:19,788,087...19,854,515
Ensembl chr12:19,786,020...19,854,668
JBrowse link
G BRD1 bromodomain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 5:774,307...808,016
Ensembl chr 5:770,654...808,006
JBrowse link
G CCND1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296
JBrowse link
G CDH1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17520682 NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986
JBrowse link
G CMTR2 cap methyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 6:14,325,869...14,334,043
Ensembl chr 6:14,323,981...14,334,008
JBrowse link
G CNTN6 contactin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr13:57,754,233...58,014,830
Ensembl chr13:57,719,846...58,014,970
JBrowse link
G CREBBP CREB binding protein ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 More... NCBI chr 3:38,388,366...38,530,243
Ensembl chr 3:38,388,547...38,530,224
JBrowse link
G DAPK1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr10:27,724,644...27,954,708
Ensembl chr10:27,724,648...27,954,350
JBrowse link
G DTL denticleless E3 ubiquitin protein ligase homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 9:131,225,840...131,275,426
Ensembl chr 9:131,227,705...131,275,451
JBrowse link
G DTX4 deltex E3 ubiquitin ligase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 2:12,197,943...12,237,884
Ensembl chr 2:12,199,231...12,237,615
JBrowse link
G EFHD1 EF-hand domain family member D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr15:133,120,092...133,169,430
Ensembl chr15:133,120,093...133,169,428
JBrowse link
G EN1 engrailed homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr15:24,402,605...24,408,377
Ensembl chr15:24,402,370...24,407,692
JBrowse link
G EP300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760
JBrowse link
G ERBIN erbb2 interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr16:44,415,106...44,533,353
Ensembl chr16:44,415,189...44,533,349
JBrowse link
G ESPL1 extra spindle pole bodies like 1, separase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 5:18,486,969...18,509,913
Ensembl chr 5:18,487,052...18,509,913
JBrowse link
G FANCA FA complementation group A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 6:253,207...300,159
Ensembl chr 6:253,207...300,152
JBrowse link
G FAT1 FAT atypical cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr17:8,466,099...8,580,715
Ensembl chr17:8,457,187...8,580,715
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:26619011 NCBI chr 8:76,482,027...76,699,354
Ensembl chr 8:76,482,844...76,699,348
JBrowse link
G FGF16 fibroblast growth factor 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr  X:61,551,487...61,561,807
Ensembl chr  X:61,552,460...61,561,954
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar PMID:26619011 NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425
JBrowse link
G FGFR4 fibroblast growth factor receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 2:80,841,536...80,853,791
Ensembl chr 2:80,841,536...80,853,796
JBrowse link
G FOXO3 forkhead box O3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 1:74,626,673...74,760,323
Ensembl chr 1:74,628,218...74,760,325
JBrowse link
G FOXP2 forkhead box P2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr18:31,335,102...31,890,523
Ensembl chr18:31,335,264...31,888,845
JBrowse link
G GAS2 growth arrest specific 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 2:36,712,758...36,885,436
Ensembl chr 2:36,711,612...36,885,620
JBrowse link
G GAS6 growth arrest specific 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr11:78,848,797...78,880,733
Ensembl chr11:78,848,797...78,881,284
JBrowse link
G GINS2 GINS complex subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 6:3,218,655...3,252,740
Ensembl chr 6:3,218,702...3,243,899
JBrowse link
G GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 8:44,448,758...44,520,737
Ensembl chr 8:44,449,290...44,518,135
JBrowse link
G HOMER3 homer scaffold protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 2:58,913,949...58,922,474
Ensembl chr 2:58,913,992...58,922,474
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 2:299,662...302,539
Ensembl chr 2:299,660...302,501
JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More... NCBI chr15:111,341,153...111,362,330
Ensembl chr15:111,341,153...111,362,296
JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr15:118,822,092...118,850,985
Ensembl chr15:118,822,047...118,850,976
JBrowse link
G IL17RD interleukin 17 receptor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr13:38,935,631...39,006,721
Ensembl chr13:38,939,316...39,006,690
JBrowse link
G INSRR insulin receptor related receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 4:93,239,678...93,258,075
Ensembl chr 4:93,239,969...93,258,075
JBrowse link
G IRX4 iroquois homeobox 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr16:78,940,033...78,944,855
Ensembl chr16:78,937,566...78,945,269
JBrowse link
G ISYNA1 inositol-3-phosphate synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 2:59,363,672...59,367,003
Ensembl chr 2:59,363,716...59,367,002
JBrowse link
G ITGB4 integrin subunit beta 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr12:5,651,292...5,685,601
Ensembl chr12:5,651,292...5,685,611
JBrowse link
G JAG1 jagged canonical Notch ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr17:19,591,248...19,629,659
Ensembl chr17:19,591,259...19,629,641
JBrowse link
G JAK3 Janus kinase 3 ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:14615376 PMID:28492532 PMID:33040328 NCBI chr 2:59,905,901...59,926,504
Ensembl chr 2:59,905,919...59,926,495
JBrowse link
G JMJD1C jumonji domain containing 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr14:66,640,845...66,966,911
Ensembl chr14:66,640,849...66,920,324
JBrowse link
G KANSL1 KAT8 regulatory NSL complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr12:16,901,611...17,096,912
Ensembl chr12:16,903,450...17,096,916
JBrowse link
G KAT6A lysine acetyltransferase 6A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr17:11,002,818...11,109,974 JBrowse link
G KDM6A lysine demethylase 6A exacerbates ISO CTD Direct Evidence: marker/mechanism
DNA:mutations:multiple: (human)
DNA:splice-site mutation, missense mutations:splice junction, CDS:multiple: (human)
CTD
RGD
PMID:23685749 PMID:31483290 RGD:150429732 RGD:150429736 NCBI chr  X:39,953,764...40,154,197
Ensembl chr  X:39,953,814...40,154,029
JBrowse link
G KDM6B lysine demethylase 6B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr12:53,087,072...53,108,949
Ensembl chr12:53,098,964...53,108,214
JBrowse link
G KMT2C lysine methyltransferase 2C disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:23685749 PMID:31483290 RGD:150429736 NCBI chr18:4,993,213...5,279,668
Ensembl chr18:4,993,227...5,278,723
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:6695174 PMID:12460918 PMID:15696205 PMID:16361624 PMID:16618717 More... NCBI chr 5:48,508,774...48,546,260
Ensembl chr 5:48,508,811...48,549,358
JBrowse link
G KRT15 keratin 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr12:21,124,605...21,130,247
Ensembl chr12:21,124,705...21,130,241
JBrowse link
G KRT5 keratin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 5:17,862,047...17,868,397
Ensembl chr 5:17,862,051...17,868,402
JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 2:303,836...323,701
Ensembl chr 2:304,430...323,699
JBrowse link
G MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr13:46,896,515...47,568,140
Ensembl chr13:46,897,903...47,567,717
JBrowse link
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 9:100,846,693...102,171,199
Ensembl chr 9:100,847,013...102,170,004
JBrowse link
G MAML3 mastermind like transcriptional coactivator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 8:86,879,353...87,323,123
Ensembl chr 8:86,879,974...87,323,117
JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 2:74,626,739...74,651,352
Ensembl chr 2:74,626,783...74,651,348
JBrowse link
G MARCKS myristoylated alanine rich protein kinase C substrate ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 1:79,789,796...79,795,895
Ensembl chr 1:79,789,815...79,795,760
JBrowse link
G MARK2 microtubule affinity regulating kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 2:8,153,870...8,216,141
Ensembl chr 2:8,155,348...8,215,959
JBrowse link
G MECOM MDS1 and EVI1 complex locus ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr13:107,753,207...108,336,136
Ensembl chr13:107,754,482...108,335,702
JBrowse link
G MGA MAX dimerization protein MGA ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 1:129,590,645...129,697,434
Ensembl chr 1:129,594,795...129,697,408
JBrowse link
G MIER2 MIER family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 2:77,912,766...77,938,855
Ensembl chr 2:77,912,761...77,938,855
JBrowse link
G MLC1 modulator of VRAC current 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 5:571,921...593,531
Ensembl chr 5:571,963...591,822
JBrowse link
G MORF4L1 mortality factor 4 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 7:48,050,050...48,075,799
Ensembl chr 7:48,050,045...48,075,795
JBrowse link
G MYB MYB proto-oncogene, transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 PMID:26829750 NCBI chr 1:28,819,500...28,856,222
Ensembl chr 1:28,819,503...28,856,999
JBrowse link
G MYBL1 MYB proto-oncogene like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 4:68,120,078...68,159,513
Ensembl chr 4:68,119,865...68,159,509
JBrowse link
G MYCBP MYC binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 6:94,805,649...94,814,443
Ensembl chr 6:94,805,640...94,814,337
JBrowse link
G MYCN MYCN proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 3:121,543,201...121,549,678
Ensembl chr 3:121,543,109...121,549,046
JBrowse link
G NETO2 neuropilin and tolloid like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 6:37,443,534...37,506,589
Ensembl chr 6:37,443,699...37,505,736
JBrowse link
G NFIB nuclear factor I B ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 1:208,182,397...208,427,504
Ensembl chr 1:208,175,194...208,421,602
JBrowse link
G NOTCH1 notch receptor 1 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar
G NSD1 nuclear receptor binding SET domain protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 2:80,649,882...80,810,934
Ensembl chr 2:80,654,379...80,809,059
JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 treatment ISO RGD PMID:23027130 RGD:150519921 NCBI chr 1:191,535,262...191,941,675
Ensembl chr 1:191,535,301...191,925,327
JBrowse link
G PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr  X:42,947,688...42,952,222
Ensembl chr  X:42,947,692...42,949,024
JBrowse link
G PDZK1 PDZ domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 4:99,625,085...99,657,170
Ensembl chr 4:99,625,080...99,657,161
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Adenocystic carcinoma ClinVar PMID:15930273 PMID:17376864 PMID:18074223 PMID:19366826 PMID:22120714 More... NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,274,587
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 4:79,687,375...79,850,146
Ensembl chr 4:79,687,375...79,846,656
JBrowse link
G PTEN phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr14:99,929,590...100,021,619 JBrowse link
G PYGB glycogen phosphorylase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr17:30,940,457...30,995,688
Ensembl chr17:30,940,452...30,995,691
JBrowse link
G RBFOX2 RNA binding fox-1 homolog 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 5:11,633,523...11,905,325
Ensembl chr 5:11,633,541...11,903,094
JBrowse link
G SERPINF1 serpin family F member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr12:47,949,004...47,959,471
Ensembl chr12:47,948,510...47,959,470
JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr13:29,884,708...29,996,285
Ensembl chr13:29,884,719...29,996,359
JBrowse link
G SF3B1 splicing factor 3b subunit 1 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar PMID:25741868 PMID:26619011 NCBI chr15:101,274,968...101,338,018
Ensembl chr15:101,276,851...101,299,105
JBrowse link
G SLC24A3 solute carrier family 24 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr17:27,270,232...27,780,535
Ensembl chr17:27,270,093...27,780,526
JBrowse link
G SLC3A2 solute carrier family 3 member 2 disease_progression ISO RGD PMID:23516127 RGD:151361211 NCBI chr 2:8,892,071...8,919,070
Ensembl chr 2:8,892,089...8,919,072
JBrowse link
G SLC7A5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:23516127 RGD:151361211 NCBI chr 6:1,545,940...1,574,298
Ensembl chr 6:1,545,944...1,574,285
JBrowse link
G SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr 1:219,624,773...219,815,438
Ensembl chr 1:219,573,535...219,815,421
JBrowse link
G SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr14:49,874,981...49,906,043
Ensembl chr14:49,874,984...49,906,048
JBrowse link
G SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr12:21,784,410...21,807,170
Ensembl chr12:21,786,897...21,807,162
JBrowse link
G SMC1A structural maintenance of chromosomes 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr  X:46,143,738...46,202,187
Ensembl chr  X:46,144,920...46,218,543
JBrowse link
G SON SON DNA and RNA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr13:197,162,075...197,193,417
Ensembl chr13:197,162,116...197,194,078
JBrowse link
G SOX11 SRY-box transcription factor 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 3:129,797,438...129,800,568
Ensembl chr 3:129,798,854...129,800,197
JBrowse link
G SOX4 SRY-box transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 7:16,886,834...16,895,488
Ensembl chr 7:16,891,319...16,892,752
JBrowse link
G SRCAP Snf2 related CREBBP activator protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 3:17,662,374...17,702,862
Ensembl chr 3:17,664,349...17,700,219
JBrowse link
G ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 9:53,442,795...53,491,847
Ensembl chr 9:53,445,591...53,486,010
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO ClinVar Annotator: match by term: Adenoid cystic carcinoma ClinVar NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992
JBrowse link
G TLK1 tousled like kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr15:77,169,661...77,329,548
Ensembl chr15:77,170,086...77,329,402
JBrowse link
G TOP2A DNA topoisomerase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr12:22,001,300...22,028,452
Ensembl chr12:22,001,282...22,028,450
JBrowse link
G TP53 tumor protein p53 disease_progression ISO ClinVar Annotator: match by term: Adenocystic carcinoma | ClinVar Annotator: match by term: Adenoid cystic carcinoma RGD
ClinVar
PMID:1673792 PMID:1686725 PMID:6736287 PMID:7707106 PMID:7881428 More... RGD:8547828 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
G UHRF1 ubiquitin like with PHD and ring finger domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23685749 NCBI chr 2:73,898,061...73,937,727
Ensembl chr 2:73,898,071...73,931,769
JBrowse link
G VCAN versican ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 2:91,682,177...91,811,674
Ensembl chr 2:91,384,391...91,811,208
JBrowse link
G WNT5B Wnt family member 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 5:68,627,158...68,731,938
Ensembl chr 5:68,627,185...68,732,265
JBrowse link
G XRN2 5'-3' exoribonuclease 2 ISO DNA:hypermethylation:3' utr: (human) RGD PMID:21692051 RGD:11041796 NCBI chr17:29,107,641...29,193,500
Ensembl chr17:29,107,667...29,193,479
JBrowse link
G ZIM2 zinc finger imprinted 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762588 NCBI chr 6:61,157,781...61,193,706 JBrowse link
adenoid squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF1A HNF1 homeobox A ISO RGD PMID:10489374 RGD:150540314 NCBI chr14:40,868,819...40,888,322
Ensembl chr14:40,868,676...40,888,328
JBrowse link
Barrett's adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP26A1 cytochrome P450 family 26 subfamily A member 1 ISO RGD PMID:18059332 RGD:13782259 NCBI chr14:104,561,394...104,567,099
Ensembl chr14:104,563,195...104,567,095
JBrowse link
G GPX3 glutathione peroxidase 3 ISO DNA:hypermethylation
DNA:hypermethylation:promoter
RGD PMID:16229808 PMID:18664505 RGD:151665354 RGD:151665749 NCBI chr16:71,980,467...71,989,011
Ensembl chr16:71,980,475...71,989,026
JBrowse link
G GPX7 glutathione peroxidase 7 ISO DNA:hypermethylation:promoter RGD PMID:18664505 RGD:151665749 NCBI chr 6:159,590,479...159,598,768
Ensembl chr 6:159,590,482...159,599,293
JBrowse link
congenital heart defects, hamartomas of tongue, and polysyndactyly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WDPCP WD repeat containing planar cell polarity effector ISO ClinVar Annotator: match by term: Heart defect - tongue hamartoma - polysyndactyly syndrome | ClinVar Annotator: match by term: WDPCP-related condition OMIM
ClinVar
PMID:9536098 PMID:16199547 PMID:17576681 PMID:20671153 PMID:25326635 More... NCBI chr 3:78,435,154...78,726,313
Ensembl chr 3:78,268,922...78,856,893
JBrowse link
Cutaneous Telangiectasia and Cancer Syndrome, Familial term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATR ATR serine/threonine kinase ISO ClinVar Annotator: match by term: Cutaneous telangiectasia and cancer syndrome, familial OMIM
ClinVar
PMID:9536098 PMID:15987455 PMID:17010193 PMID:17576681 PMID:18414213 More... NCBI chr13:83,175,515...83,289,986
Ensembl chr13:83,174,824...83,289,989
JBrowse link
esophageal cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO protein:increased expression:esophagus (human) RGD PMID:27188433 RGD:152995510
G ALDH2 aldehyde dehydrogenase 2 family member ISO ClinVar Annotator: match by term: Esophageal cancer, alcohol-related, susceptibility to ClinVar PMID:2987944 PMID:4065146 PMID:6650498 PMID:7180842 PMID:7593603 More... NCBI chr14:39,902,317...39,933,113
Ensembl chr14:39,896,565...39,933,124
JBrowse link
G BHLHE41 basic helix-loop-helix family member e41 ISO protein:increased expression:esophagus(human) RGD PMID:29890466 RGD:151665308 NCBI chr 5:47,687,662...47,692,761
Ensembl chr 5:47,686,404...47,692,762
JBrowse link
G BRCA2 BRCA2 DNA repair associated ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:25741868 PMID:28492532 PMID:31911673 NCBI chr11:8,805,950...8,858,128
Ensembl chr11:8,805,953...8,858,418
JBrowse link
G CTNNA1 catenin alpha 1 disease_progression ISO RGD PMID:9863006 RGD:2289811 NCBI chr 2:140,682,776...140,869,828
Ensembl chr 2:140,682,371...140,871,334
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:11833070 PMID:26782562 RGD:11554919 RGD:14700950 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775
JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 ameliorates ISO RNA:decreased expression:esophagus (human) RGD PMID:14760115 RGD:152025255 NCBI chr17:55,110,546...55,130,328
Ensembl chr17:55,110,590...55,130,363
JBrowse link
G DLEC1 DLEC1 cilia and flagella associated protein ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:25741868 NCBI chr13:22,873,210...22,964,971
Ensembl chr13:22,882,629...22,964,677
JBrowse link
G FGF2 fibroblast growth factor 2 ISO RGD PMID:29660336 RGD:21409755 NCBI chr 8:101,278,877...101,344,084
Ensembl chr 8:101,278,885...101,343,916
JBrowse link
G GPX3 glutathione peroxidase 3 treatment ISO DNA:hypermethylation RGD PMID:33292587 RGD:151665781 NCBI chr16:71,980,467...71,989,011
Ensembl chr16:71,980,475...71,989,026
JBrowse link
G HMOX1 heme oxygenase 1 ISO protein:increased expression:esophagus RGD PMID:20498946 RGD:4145286
G IL10 interleukin 10 treatment ISO RGD PMID:26603620 RGD:152998997 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378
JBrowse link
G IL1R2 interleukin 1 receptor type 2 susceptibility ISO DNA:SNP:cds:rs11674595|rs2072472 (human) RGD PMID:31744444 RGD:152998961 NCBI chr 3:52,367,434...52,406,393
Ensembl chr 3:52,367,437...52,406,334
JBrowse link
G IL5 interleukin 5 treatment ISO RGD PMID:20232121 RGD:5134997 NCBI chr 2:134,832,143...134,846,141
Ensembl chr 2:134,832,147...134,835,212
JBrowse link
G LOC110258578 interleukin-1 beta-like treatment ISO RGD PMID:26603620 RGD:152998997
G LZTS1 leucine zipper tumor suppressor 1 ISO esophageal squamous cell carcinoma, OMIM:133239 RGD PMID:10097140 RGD:1600104 NCBI chr14:4,344,496...4,404,208
Ensembl chr14:4,346,480...4,404,168
JBrowse link
G MAF MAF bZIP transcription factor ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:25741868 PMID:28492532 NCBI chr 6:8,468,736...8,910,012
Ensembl chr 6:8,468,413...8,485,030
JBrowse link
G MIR155 microRNA mir-155 ISO RGD PMID:29660336 RGD:21409755 NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902
JBrowse link
G MIR21 microRNA mir-21 ISO RNA:increased expression:blood serum (human)
RNA:increased expression:esophagus (human)
RGD PMID:22638884 PMID:27188433 RGD:152995510 RGD:152998900 NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358
JBrowse link
G MXI1 MAX interactor 1, dimerization protein ISO RGD PMID:10849326 RGD:1298988 NCBI chr14:120,643,691...120,722,632
Ensembl chr14:120,643,830...120,724,099
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor ISO mRNA:splice variants:esophagus (human) RGD PMID:24527027 RGD:150519911 NCBI chr13:22,976,951...22,979,568
Ensembl chr13:22,966,137...22,983,109
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO protein:increased expression:esophagus (human) RGD PMID:27188433 RGD:152995510 NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,274,587
JBrowse link
G PTEN phosphatase and tensin homolog treatment ISO human gene and cells in a mouse model
protein:decreased expression:esophagus (human)
RGD PMID:20378992 PMID:27188433 RGD:127285592 RGD:152995510 NCBI chr14:99,929,590...100,021,619 JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO mRNA,protein:decreased expression:esophagus: RGD PMID:33862112 RGD:151232285 NCBI chr 3:31,879,143...31,883,041
Ensembl chr 3:31,881,225...31,884,967
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:7664267 PMID:9395234 PMID:9536098 PMID:10789724 PMID:11212236 More... NCBI chr13:16,784,370...16,875,828
Ensembl chr13:16,784,490...16,878,160
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 disease_progression
severity
ISO DNA:SNP:intron 6: (rs610604) (human)
DNA:SNP:3'utr: (rs583522) (human)
RGD PMID:25354935 PMID:26598072 RGD:11075880 RGD:151347597 NCBI chr 1:26,474,158...26,489,771
Ensembl chr 1:26,473,938...26,489,822
JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:7887414 PMID:8023157 PMID:8118819 PMID:8164043 PMID:8825920 More... NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
G WWOX WW domain containing oxidoreductase ISO ClinVar Annotator: match by term: Esophagus cancer ClinVar PMID:24456803 PMID:25411445 PMID:25741868 PMID:26467025 PMID:28492532 More... NCBI chr 6:8,910,209...9,871,048
Ensembl chr 6:8,910,138...9,871,053
JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility ISO DNA:missense mutation:exon 9: p.T304A, c.910A>G (human) RGD PMID:24345911 RGD:150530620 NCBI chr 6:50,403,691...50,425,730
Ensembl chr 6:50,403,689...50,425,729
JBrowse link
esophageal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC7 baculoviral IAP repeat containing 7 disease_progression ISO mRNA:increased expression:esophagus (human) RGD PMID:31964418 RGD:153344516 NCBI chr17:62,351,663...62,356,220 JBrowse link
G BRCA2 BRCA2 DNA repair associated ISO ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:17972177 PMID:18431501 PMID:18627636 PMID:18779604 PMID:21120943 More... NCBI chr11:8,805,950...8,858,128
Ensembl chr11:8,805,953...8,858,418
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:25741868 PMID:26619011 PMID:28492532 NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854
JBrowse link
G CTNNB1 catenin beta 1 ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:9065402 PMID:9065403 PMID:9294210 PMID:10027390 PMID:10192393 More... NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311
JBrowse link
G DCC DCC netrin 1 receptor ISO ClinVar Annotator: match by term: Esophageal carcinoma, somatic ClinVar PMID:8187090 NCBI chr 1:101,518,629...103,087,021
Ensembl chr 1:101,846,100...103,083,096
JBrowse link
G EGFR epidermal growth factor receptor ISO ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:15623594 PMID:16205628 PMID:16707764 PMID:16863509 PMID:17653080 More... NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589
JBrowse link
G EP300 E1A binding protein p300 ISO ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:26619011 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:16397024 PMID:23220880 PMID:25157968 PMID:26619011 NCBI chr12:22,591,621...22,621,384
Ensembl chr12:22,590,725...22,621,351
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:25741868 PMID:26619011 NCBI chr 8:76,482,027...76,699,354
Ensembl chr 8:76,482,844...76,699,348
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:25157968 PMID:26619011 NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425
JBrowse link
G GRB7 growth factor receptor bound protein 7 exacerbates ISO mRNA:increased expression:esophagus mucosa (human) RGD PMID:8988034 RGD:151347660 NCBI chr12:22,574,579...22,583,386
Ensembl chr12:22,574,584...22,582,345
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 2:299,662...302,539
Ensembl chr 2:299,660...302,501
JBrowse link
G HTRA1 HtrA serine peptidase 1 disease_progression ISO mRNA,protein:decreased expression:esophagus (human) RGD PMID:22935172 RGD:152985525 NCBI chr14:132,043,044...132,103,590
Ensembl chr14:132,041,934...132,103,595
JBrowse link
G JAK2 Janus kinase 2 treatment ISO associated with Immune Deficiency Disease, human cells in mouse model RGD PMID:25724470 RGD:127285656 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:16361624 PMID:16618717 PMID:18316791 PMID:19114683 PMID:19679400 More... NCBI chr 5:48,508,774...48,546,260
Ensembl chr 5:48,508,811...48,549,358
JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:11150980 PMID:16155195 PMID:16170316 PMID:16329078 PMID:16372351 More... NCBI chr 2:303,836...323,701
Ensembl chr 2:304,430...323,699
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 exacerbates ISO mRNA:decreased expression:espohagus (human) RGD PMID:32831056 RGD:155630592 NCBI chr 2:71,299,010...71,308,432
Ensembl chr 2:71,298,325...71,308,124
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO ClinVar Annotator: match by term: Carcinoma of esophagus ClinVar PMID:25157968 PMID:26619011 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma
ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,274,587
JBrowse link
G RHOA ras homolog family member A ISO ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:26619011 NCBI chr13:31,918,484...31,991,207
Ensembl chr13:31,918,834...31,986,607
JBrowse link
G SLC7A5 solute carrier family 7 member 5 severity ISO RGD PMID:15906366 RGD:151361282 NCBI chr 6:1,545,940...1,574,298
Ensembl chr 6:1,545,944...1,574,285
JBrowse link
G SMAD4 SMAD family member 4 ISO ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:6604412 PMID:8898652 PMID:9214508 PMID:9285566 PMID:9582123 More... NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,589,850...100,628,029
JBrowse link
G STAT3 signal transducer and activator of transcription 3 treatment ISO associated with Immune Deficiency Disease, human cells in mouse model RGD PMID:25724470 RGD:127285656 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992
JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Carcinoma of esophagus | ClinVar Annotator: match by term: Esophageal carcinoma ClinVar PMID:124622 PMID:253702 PMID:960674 PMID:1349175 PMID:1359493 More... NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
Esophageal Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21332314 NCBI chr 9:93,049,955...93,146,469 JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,708
JBrowse link
G ACTB actin beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 3:4,084,275...4,090,383
Ensembl chr 3:4,082,216...4,090,356
JBrowse link
G AKAP13 A-kinase anchoring protein 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr 7:87,889,384...88,222,854 JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:8850269 NCBI chr14:39,902,317...39,933,113
Ensembl chr14:39,896,565...39,933,124
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11406566 NCBI chr12:52,287,174...52,295,873
Ensembl chr12:52,287,160...52,295,871
JBrowse link
G AQP3 aquaporin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21401805 NCBI chr10:33,045,374...33,050,285
Ensembl chr10:33,045,245...33,051,082
JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:17634542 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140
JBrowse link
G BBC3 BCL2 binding component 3 ISO CTD Direct Evidence: therapeutic CTD PMID:16481741 NCBI chr 6:53,037,103...53,046,902
Ensembl chr 6:53,037,104...53,046,887
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G BCL2A1 BCL2 related protein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17634542 NCBI chr 7:48,887,227...48,897,667
Ensembl chr 7:48,887,094...48,897,870
JBrowse link
G BSG basigin ISO CTD Direct Evidence: marker/mechanism CTD PMID:36574092 NCBI chr 2:77,735,586...77,743,451 JBrowse link
G CASP8 caspase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17450141 PMID:21472143 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
JBrowse link
G CCND1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12235107 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296
JBrowse link
G CCNH cyclin H ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 2:94,980,938...95,019,053
Ensembl chr 2:94,980,941...95,018,634
JBrowse link
G CDH13 cadherin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18729198 NCBI chr 6:4,809,752...5,832,188
Ensembl chr 6:4,808,255...5,832,415
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A disease_progression ISO RGD PMID:11903577 RGD:8662379 NCBI chr 7:32,354,776...32,363,771
Ensembl chr 7:32,359,455...32,363,761
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism
Protein:decreased expression:esophagus
CTD
RGD
PMID:10969811 PMID:18410530 RGD:1600828 NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854
JBrowse link
G CRYAB crystallin alpha B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 9:39,638,505...39,643,530
Ensembl chr 9:39,638,506...39,643,530
JBrowse link
G CSF3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:7692001 NCBI chr12:22,333,445...22,335,949
Ensembl chr12:22,333,449...22,338,753
JBrowse link
G CXCL2 chemokine (C-X-C motif) ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21509778 NCBI chr 8:70,157,253...70,159,145
Ensembl chr 8:70,157,214...70,159,138
JBrowse link
G CYP19A3 cytochrome P450 19A3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899
JBrowse link
G CYP26A1 cytochrome P450 family 26 subfamily A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18059332 NCBI chr14:104,561,394...104,567,099
Ensembl chr14:104,563,195...104,567,095
JBrowse link
G DCC DCC netrin 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 1:101,518,629...103,087,021
Ensembl chr 1:101,846,100...103,083,096
JBrowse link
G EGFR epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21298351 PMID:21468131 PMID:22042947 NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589
JBrowse link
G ENO1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 6:69,385,879...69,401,664
Ensembl chr 6:69,385,879...69,401,151
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22042947 NCBI chr12:22,591,621...22,621,384
Ensembl chr12:22,590,725...22,621,351
JBrowse link
G FAS Fas cell surface death receptor ISO protein:decreased expression:esophageal mucosa: RGD PMID:9605741 RGD:11049151 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716
JBrowse link
G FASLG Fas ligand ISO protein:increased expression:esophageal mucosa: RGD PMID:9605741 RGD:11049151 NCBI chr 9:115,068,314...115,075,147
Ensembl chr 9:115,068,090...115,076,464
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,679...64,133,991
JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917
JBrowse link
G GNG7 G protein subunit gamma 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18219292 NCBI chr 2:75,929,877...76,083,557
Ensembl chr 2:76,039,656...76,083,555
JBrowse link
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 1:68,052,086...68,680,448
Ensembl chr 1:68,057,538...68,679,256
JBrowse link
G KDR kinase insert domain receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 PMID:35917945 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,122...41,856,336
JBrowse link
G LGALS3 galectin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17634542 NCBI chr 1:184,478,639...184,496,155
Ensembl chr 1:184,478,710...184,497,951
JBrowse link
G LOC100512795 alcohol dehydrogenase class 4 mu/sigma chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:18500343 NCBI chr 8:121,020,683...121,041,735
Ensembl chr 8:121,020,969...121,041,506
JBrowse link
G LOC100737977 tumor necrosis factor receptor superfamily member 10B-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr14:7,344,788...7,371,086 JBrowse link
G LZTS1 leucine zipper tumor suppressor 1 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr14:4,344,496...4,404,208
Ensembl chr14:4,346,480...4,404,168
JBrowse link
G MACIR macrophage immunometabolism regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 2:108,733,347...108,753,276
Ensembl chr 2:108,733,357...108,753,275
JBrowse link
G MAP3K3 mitogen-activated protein kinase kinase kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr12:15,228,979...15,298,784
Ensembl chr12:15,230,182...15,298,784
JBrowse link
G MARCHF8 membrane associated ring-CH-type finger 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr14:90,725,550...90,854,835
Ensembl chr14:90,725,574...90,854,828
JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22042947 NCBI chr18:29,426,044...29,541,526
Ensembl chr18:29,426,048...29,541,512
JBrowse link
G MIR145 microRNA mir-145 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21248297 NCBI chr 2:150,580,126...150,580,211
Ensembl chr 2:150,580,126...150,580,211
JBrowse link
G MIR21 microRNA mir-21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21248297 NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358
JBrowse link
G MIR98 microRNA mir-98 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27270317 NCBI chr  X:46,302,381...46,302,460
Ensembl chr  X:46,302,381...46,302,460
JBrowse link
G MMP14 matrix metallopeptidase 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr 7:76,174,502...76,185,931
Ensembl chr 7:76,172,971...76,185,928
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor treatment ISO RGD PMID:22844359 RGD:7207890 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078
JBrowse link
G NOS2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15264214 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146
JBrowse link
G NOS3 nitric oxide synthase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21472143 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943
JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21977915 NCBI chr13:140,373,571...140,406,129
Ensembl chr13:140,364,075...140,406,112
JBrowse link
G PHB1 prohibitin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr12:25,596,520...25,609,693
Ensembl chr12:25,596,523...25,609,706
JBrowse link
G PRDX1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 6:165,847,390...165,859,918
Ensembl chr 6:165,824,395...165,861,442
JBrowse link
G PRDX2 peroxiredoxin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 2:66,207,829...66,211,474
Ensembl chr 2:66,207,828...66,212,009
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12189197 NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 susceptibility ISO mRNA,protein:increased expression:Esophagus
DNA:SNPs: :-1195A > G, -765G > C (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11059772 PMID:16083713 PMID:16322294 PMID:17707579 PMID:22165968 RGD:5135528 RGD:5687745 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
JBrowse link
G RNF6 ring finger protein 6 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr11:4,020,752...4,033,040
Ensembl chr11:4,020,852...4,031,787
JBrowse link
G RPRM reprimo, TP53 dependent G2 arrest mediator homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:17121882 NCBI chr15:61,140,687...61,143,397
Ensembl chr15:61,140,688...61,142,607
JBrowse link
G RUNX3 RUNX family transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18058463 NCBI chr 6:82,531,203...82,595,044
Ensembl chr 6:82,531,559...82,595,026
JBrowse link
G SFN stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 6:84,188,521...84,189,824
Ensembl chr 6:84,188,445...84,189,827
JBrowse link
G SLC30A7 solute carrier family 30 member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr 4:117,320,229...117,396,383
Ensembl chr 4:117,314,845...117,396,495
JBrowse link
G SMYD2 SET and MYND domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25825497 NCBI chr 9:129,263,524...129,316,226
Ensembl chr 9:129,263,526...129,316,349
JBrowse link
G SNAI2 snail family transcriptional repressor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr 4:79,264,880...79,268,475
Ensembl chr 4:79,264,880...79,268,475
JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11053990 PMID:15986332 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
JBrowse link
G SST somatostatin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17999418 NCBI chr13:125,337,560...125,338,742
Ensembl chr13:125,337,418...125,338,850
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10789724 NCBI chr13:16,784,370...16,875,828
Ensembl chr13:16,784,490...16,878,160
JBrowse link
G TGM2 transglutaminase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17068819 NCBI chr17:41,186,765...41,221,686
Ensembl chr17:41,186,770...41,221,637
JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:esophageal mucosa:
CTD
RGD
PMID:12706858 PMID:16778087 PMID:17634542 PMID:26192916 PMID:26439224 RGD:11075085 RGD:8547873 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
G TPM1 tropomyosin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 1:108,986,981...109,016,090
Ensembl chr 1:108,986,986...109,020,035
JBrowse link
G TPM4 tropomyosin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 2:61,453,721...61,476,781
Ensembl chr 2:61,453,725...61,476,781
JBrowse link
G TRMT11 tRNA methyltransferase 11 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 1:36,930,857...37,002,079
Ensembl chr 1:36,940,334...37,002,056
JBrowse link
G TUFM Tu translation elongation factor, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:15986332 NCBI chr 3:18,521,119...18,524,705
Ensembl chr 3:18,521,128...18,524,959
JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15930319 NCBI chr 8:32,353,766...32,367,288
Ensembl chr 8:32,353,246...32,367,332
JBrowse link
G WIF1 WNT inhibitory factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17384664 NCBI chr 5:29,450,442...29,543,913
Ensembl chr 5:29,450,442...29,543,913
JBrowse link
G WWOX WW domain containing oxidoreductase ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 6:8,910,209...9,871,048
Ensembl chr 6:8,910,138...9,871,053
JBrowse link
G XIAP X-linked inhibitor of apoptosis ISO CTD Direct Evidence: marker/mechanism CTD PMID:17611394 NCBI chr  X:101,399,374...101,440,021
Ensembl chr  X:101,399,812...101,440,013
JBrowse link
G XRCC3 X-ray repair cross complementing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21347786
esophagus adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase onset ISO DNA:SNP:3'utr: (rs4740363) (human) RGD PMID:21472143 RGD:126925218 NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,708
JBrowse link
G ARID1A AT-rich interaction domain 1A disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:23525077 PMID:31906887 RGD:127285649 NCBI chr 6:84,049,729...84,124,302
Ensembl chr 6:84,049,087...84,123,349
JBrowse link
G BARX1 BARX homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24121790 NCBI chr 3:43,284,609...43,288,269
Ensembl chr 3:43,284,464...43,288,281
JBrowse link
G BCL2 BCL2 apoptosis regulator onset ISO DNA:SNPs:3'utr: (rs720321, rs17757541) (human) RGD PMID:21472143 RGD:126925218 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879
JBrowse link
G BECN1 beclin 1 ISO RGD PMID:22301112 RGD:11561943 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 treatment ISO RGD PMID:26291056 RGD:152999007 NCBI chr 9:33,003,570...33,020,252
Ensembl chr 9:33,003,276...33,020,242
JBrowse link
G CASP8 caspase 8 onset ISO DNA:SNP:5'utr: (rs1035142) (human) RGD PMID:21472143 RGD:126925218 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
JBrowse link
G CDC5L cell division cycle 5 like disease_progression ISO protein:increased expression:esophageal mucosa (human) RGD PMID:15725809 RGD:10047052 NCBI chr 7:39,384,397...39,427,729
Ensembl chr 7:39,384,556...39,431,248
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854
JBrowse link
G CRTC1 CREB regulated transcription coactivator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24121790 NCBI chr 2:59,069,334...59,157,196
Ensembl chr 2:59,069,335...59,157,176
JBrowse link
G CTSB cathepsin B ISO RGD PMID:9770500 RGD:734853 NCBI chr14:15,014,139...15,035,081
Ensembl chr14:15,011,711...15,033,877
JBrowse link
G CYP19A3 cytochrome P450 19A3 onset ISO DNA:SNP:5'utr: (rs2445762) (human) RGD PMID:21472143 RGD:126925218 NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899
JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 treatment ISO mRNA:increased expression:esophagus (human) RGD PMID:30187205 RGD:151665176 NCBI chr17:55,110,546...55,130,328
Ensembl chr17:55,110,590...55,130,363
JBrowse link
G DOCK2 dedicator of cytokinesis 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr16:53,843,248...54,248,708
Ensembl chr16:53,843,252...54,248,638
JBrowse link
G ELMO1 engulfment and cell motility 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr18:36,755,026...37,336,095
Ensembl chr18:36,786,378...37,347,283
JBrowse link
G EMX2 empty spiracles homeobox 2 ISO protein:decreased expression:esophagus (human) RGD PMID:31432154 RGD:153323302 NCBI chr14:127,649,675...127,656,972
Ensembl chr14:127,650,688...127,655,706
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit susceptibility ISO DNA:snps:cds, 3' utr:c.354C>T, c.8092C>A (human) RGD PMID:18478337 RGD:13207314 NCBI chr 6:51,783,537...51,808,898
Ensembl chr 6:51,783,478...51,798,984
JBrowse link
G FAS Fas cell surface death receptor ISO associated with Barrett Esophagus;protein:increased expression:esophageal mucosa (human) RGD PMID:10340890 RGD:8662425 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716
JBrowse link
G FOXA1 forkhead box A1 ISO protein:increased expression:esophagus RGD PMID:12234996 RGD:151665758 NCBI chr 7:62,471,233...62,479,638
Ensembl chr 7:62,471,249...62,479,220
JBrowse link
G FOXP1 forkhead box P1 ISO DNA:snps:intron, enhancer:g.70959438A>G, g.70879779A>C (rs9837992, rs2687201) (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:24121790 PMID:26383589 RGD:11535321 NCBI chr13:52,346,844...52,974,358
Ensembl chr13:52,348,234...52,876,892
JBrowse link
G GHRL ghrelin and obestatin prepropeptide onset ISO DNA:SNP:5'utr: (rs696217) (human) RGD PMID:21472143 RGD:126925218 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917
JBrowse link
G GPX3 glutathione peroxidase 3 susceptibility ISO DNA:SNPs:intron: (rs4958872, rs3792797) (human) RGD PMID:22715394 RGD:152995500 NCBI chr16:71,980,467...71,989,011
Ensembl chr16:71,980,475...71,989,026
JBrowse link
G GRB7 growth factor receptor bound protein 7 treatment
exacerbates
ISO human cells in a mouse model RGD PMID:31809243 PMID:32737994 RGD:151347656 RGD:151347659 NCBI chr12:22,574,579...22,583,386
Ensembl chr12:22,574,584...22,582,345
JBrowse link
G KDR kinase insert domain receptor onset ISO DNA:SNP:5'utr: (rs11941492) (human) RGD PMID:21472143 RGD:126925218 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,122...41,856,336
JBrowse link
G LOC100737977 tumor necrosis factor receptor superfamily member 10B-like onset ISO DNA:SNP:3'utr: (rs11775256) (human) RGD PMID:21472143 RGD:126925218 NCBI chr14:7,344,788...7,371,086 JBrowse link
G MIR21 microRNA mir-21 disease_progression ISO RGD PMID:26481465 RGD:41404702 NCBI chr12:36,065,267...36,065,358
Ensembl chr12:36,065,267...36,065,358
JBrowse link
G MMP1 matrix metallopeptidase 1 susceptibility ISO DNA:insertion:promoter:g.-1607insG rs1799750 (human) RGD PMID:19321798 RGD:7207058 NCBI chr 9:33,411,738...33,420,205
Ensembl chr 9:33,411,065...33,420,076
JBrowse link
G MMP12 matrix metallopeptidase 12 ISO DNA:snp:promoter:g.-82A>G rs2276109 (human) RGD PMID:19321798 RGD:7207058 NCBI chr 9:33,473,625...33,483,630
Ensembl chr 9:33,473,093...33,483,679
JBrowse link
G MMP14 matrix metallopeptidase 14 onset ISO DNA:SNP:5'utr: (rs2236302) (human) RGD PMID:21472143 RGD:126925218 NCBI chr 7:76,174,502...76,185,931
Ensembl chr 7:76,172,971...76,185,928
JBrowse link
G MMP3 matrix metallopeptidase 3 ISO DNA:insertion:promoter:g.-1613insA rs3025058 (human) RGD PMID:19321798 RGD:7207058 NCBI chr 9:33,446,969...33,453,995
Ensembl chr 9:33,446,836...33,454,000
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO protein:increased expression:esophagus RGD PMID:25562781 RGD:13204790 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788
JBrowse link
G NELL1 neural EGFL like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17452981 NCBI chr 2:37,809,080...38,754,520
Ensembl chr 2:37,809,008...38,754,525
JBrowse link
G NOS3 nitric oxide synthase 3 onset ISO DNA:SNP:3'utr: (rs2070744) (human) RGD PMID:21472143 RGD:126925218 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,274,587
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO mRNA,protein:increased expression:Esophagus RGD PMID:22165968 RGD:5687745 NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 disease_progression ISO protein: increased expression: esophagus
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12055587 PMID:12507933 RGD:13207437 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
JBrowse link
G SLC22A18 solute carrier family 22 member 18 disease_progression ISO DNA:hypermethylation: (human) RGD PMID:23243219 RGD:150557426 NCBI chr 2:2,032,370...2,055,756
Ensembl chr 2:2,028,396...2,055,750
JBrowse link
G SMAD4 SMAD family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 PMID:24952744 NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,589,850...100,628,029
JBrowse link
G SMO smoothened, frizzled class receptor treatment ISO RGD PMID:23108119 RGD:150340553 NCBI chr18:19,450,730...19,478,796
Ensembl chr18:19,450,743...19,478,898
JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:17785574 RGD:2317403 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
JBrowse link
G SPART spartin ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr11:12,313,211...12,346,226
Ensembl chr11:12,313,210...12,374,645
JBrowse link
G TLR4 toll like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,058,970
JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23525077 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
G VDR vitamin D receptor susceptibility
disease_progression
ISO DNA:SNPs,haplotype:exon:rs1989969,rs2238135 (human)
DNA:amplication: :
RGD PMID:24951052 PMID:25910066 RGD:11055189 RGD:13432070 NCBI chr 5:78,205,807...78,266,505
Ensembl chr 5:78,205,810...78,266,475
JBrowse link
esophagus small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC110255312 keratin, type I cytoskeletal 14 ISO protein:increased expression:esophagus RGD PMID:16140947 RGD:1600174 NCBI chr12:21,074,965...21,079,393
Ensembl chr12:21,024,314...21,119,396
JBrowse link
esophagus squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC2 ATP binding cassette subfamily C member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21206495 NCBI chr14:110,955,698...111,038,898
Ensembl chr14:110,955,633...111,037,537
JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 6:105,414,628...105,422,294
Ensembl chr 6:105,414,631...105,422,294
JBrowse link
G AJUBA ajuba LIM protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 7:76,063,009...76,072,884
Ensembl chr 7:76,063,058...76,076,585
JBrowse link
G AKT1 AKT serine/threonine kinase 1 disease_progression ISO protein:increased expression:esophagus (human) RGD PMID:32642408 RGD:152995512
G ALDH2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:16639733 PMID:22960999 NCBI chr14:39,902,317...39,933,113
Ensembl chr14:39,896,565...39,933,124
JBrowse link
G ANXA1 annexin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 1:226,414,200...226,431,963
Ensembl chr 1:226,414,306...226,432,279
JBrowse link
G ATM ATM serine/threonine kinase disease_progression ISO Smoke Inhalation Injury; mRNA:increased expression:esophagus (human) RGD PMID:17019709 RGD:150340713 NCBI chr 9:36,620,656...36,759,555
Ensembl chr 9:36,620,658...36,759,552
JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25129146 NCBI chr12:52,925,697...52,932,638
Ensembl chr12:52,925,693...52,932,635
JBrowse link
G AXIN1 axin 1 disease_progression ISO protein:decreased expression:esophagus (human) RGD PMID:12771989 RGD:150530473 NCBI chr 3:41,344,908...41,393,999
Ensembl chr 3:41,337,071...41,393,997
JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding disease_progression ISO RGD PMID:28053542 RGD:153350138 NCBI chr 3:7,867,521...7,874,857 JBrowse link
G AZIN1 antizyme inhibitor 1 ISO RGD PMID:24302582 RGD:14700707 NCBI chr 4:34,221,368...34,257,261
Ensembl chr 4:34,234,679...34,257,134
JBrowse link
G B2M beta-2-microglobulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 1:126,837,721...126,844,043
Ensembl chr 1:126,835,143...126,981,582
JBrowse link
G BLVRB biliverdin reductase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 6:48,715,540...48,728,433
Ensembl chr 6:48,715,199...48,728,389
JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger ISO RGD PMID:21165554 RGD:126781701 NCBI chr10:52,586,089...52,596,154
Ensembl chr10:52,586,509...52,596,564
JBrowse link
G BMP6 bone morphogenetic protein 6 ISO protein:increased expression:esophagus RGD PMID:22364398 RGD:7242413 NCBI chr 7:5,058,817...5,208,868
Ensembl chr 7:5,058,817...5,210,270
JBrowse link
G BRCA1 BRCA1 DNA repair associated ISO DNA:SNP: :rs799917 (human) RGD PMID:23749772 RGD:126925960 NCBI chr12:19,788,087...19,854,515
Ensembl chr12:19,786,020...19,854,668
JBrowse link
G BRCA2 BRCA2 DNA repair associated ISO DNA:nonsense mutation: :p.K3326X (human) RGD PMID:21279724 RGD:11344913 NCBI chr11:8,805,950...8,858,128
Ensembl chr11:8,805,953...8,858,418
JBrowse link
G BST2 bone marrow stromal cell antigen 2 disease_progression ISO RGD PMID:26832883 RGD:14398496 NCBI chr 2:60,305,306...60,308,295
Ensembl chr 2:60,305,283...60,309,697
JBrowse link
G BUB1B BUB1 mitotic checkpoint serine/threonine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18691855 NCBI chr 1:131,093,026...131,143,840
Ensembl chr 1:131,092,958...131,143,794
JBrowse link
G CA1 carbonic anhydrase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 4:51,343,548...51,353,127
Ensembl chr 4:51,302,406...51,353,126
JBrowse link
G CA12 carbonic anhydrase 12 severity ISO RGD PMID:26316888 RGD:155226859 NCBI chr 1:108,649,277...108,710,658
Ensembl chr 1:108,649,271...108,710,651
JBrowse link
G CA2 carbonic anhydrase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 4:51,194,686...51,211,436
Ensembl chr 4:51,193,756...51,211,259
JBrowse link
G CALR calreticulin ameliorates ISO CTD Direct Evidence: marker/mechanism
human cells in a mouse model
CTD
RGD
PMID:19684620 PMID:21517111 PMID:23814025 RGD:150521679 RGD:150521703 NCBI chr 2:66,098,263...66,102,074
Ensembl chr 2:66,098,229...66,102,132
JBrowse link
G CAPZA1 capping actin protein of muscle Z-line subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 4:107,769,570...107,821,806
Ensembl chr 4:107,768,079...107,821,819
JBrowse link
G CASP8 caspase 8 exacerbates ISO mRNA,protein:decreased expression:esophagus squamous epithelium (human) RGD PMID:31885720 RGD:153300949 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
JBrowse link
G CBX8 chromobox 8 severity ISO mRNA:increased expression:esophagus: RGD PMID:25197352 RGD:9587436 NCBI chr12:2,562,419...2,565,035
Ensembl chr12:2,562,374...2,565,780
JBrowse link
G CCHCR1 coiled-coil alpha-helical rod protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr 7:23,543,919...23,558,150
Ensembl chr 7:23,544,121...23,558,052
JBrowse link
G CCND1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO CTD Direct Evidence: therapeutic CTD PMID:15375580 NCBI chr 7:32,354,776...32,363,771
Ensembl chr 7:32,359,455...32,363,761
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854
JBrowse link
G CDKN2B cyclin dependent kinase inhibitor 2B ISO DNA:SNPs: :rs615552, rs573687 (human) RGD PMID:23361049 RGD:7248756 NCBI chr 1:200,666,250...200,770,880
Ensembl chr 1:200,761,004...200,766,056
JBrowse link
G CFL1 cofilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035
JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit susceptibility ISO DNA:SNP: :rs667282(human)
mRNA:increased expression:esophagus (human)
RGD PMID:23844051 PMID:27610024 RGD:150524358 RGD:151361143 NCBI chr 7:47,382,860...47,425,871
Ensembl chr 7:47,383,792...47,425,841
JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit exacerbates
disease_progression
ISO mRNA:increased expression:esophagus (human) RGD PMID:27610024 PMID:33603170 RGD:151361143 RGD:151667905 NCBI chr 1:142,803,697...142,937,124
Ensembl chr 1:142,803,701...142,937,123
JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit ISO mRNA:increased expression:esophagus (human) RGD PMID:27610024 RGD:151361143 NCBI chr 7:47,338,819...47,359,064 JBrowse link
G CLIC1 chloride intracellular channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 7:23,842,829...23,851,162 JBrowse link
G CLPTM1L CLPTM1 like no_association
susceptibility
ISO mRNA:increased expression:esophagus
DNA:SNP: :rs401681(human)
DNA:SNP: :rs451360(human)
RGD PMID:24386361 PMID:25007268 PMID:25480402 PMID:26716642 RGD:11572962 RGD:150530488 RGD:150530497 RGD:150537098 NCBI chr16:79,237,000...79,248,503
Ensembl chr16:79,237,061...79,248,500
JBrowse link
G COL14A1 collagen type XIV alpha 1 chain disease_progression ISO DNA:hypermethylation RGD PMID:25050929 RGD:151665741 NCBI chr 4:18,690,197...18,925,111
Ensembl chr 4:18,690,198...18,924,971
JBrowse link
G CRABP1 cellular retinoic acid binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17438526 NCBI chr 7:47,602,316...47,608,865
Ensembl chr 7:47,602,192...47,608,970
JBrowse link
G CREBBP CREB binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 3:38,388,366...38,530,243
Ensembl chr 3:38,388,547...38,530,224
JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO mRNA:decreased expression:esophagus squamous epithelium (human) RGD PMID:32038997 RGD:150524298 NCBI chr 2:151,102,138...151,130,311
Ensembl chr 2:151,102,147...151,147,633
JBrowse link
G CSTB cystatin B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr13:206,706,060...206,710,598
Ensembl chr13:206,706,063...206,710,646
JBrowse link
G CTNNB1 catenin beta 1 ISO ClinVar Annotator: match by term: Esophageal squamous cell carcinoma ClinVar PMID:25157968 PMID:25741868 PMID:26619011 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 severity ISO mRNA:increased expression:esophagus (human) RGD PMID:31423201 RGD:150520019 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 disease_progression ISO protein:increased expression:esophagus squamous epithelium (human) RGD PMID:17171785 RGD:152023646 NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,232
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:11860825 RGD:14700943 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO protein:increased expression:esophagus (rat) RGD PMID:18618592 RGD:7829715 NCBI chr 3:102,195,743...102,205,687
Ensembl chr 3:102,195,741...102,205,683
JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 susceptibility ISO DNA:SNP:CDS: (rs2296241) (human) RGD PMID:28362172 RGD:151665500 NCBI chr17:55,110,546...55,130,328
Ensembl chr17:55,110,590...55,130,363
JBrowse link
G CYP26B1 cytochrome P450 family 26 subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr 3:70,573,551...70,593,416
Ensembl chr 3:70,572,197...70,593,408
JBrowse link
G DAB2IP DAB2 interacting protein severity ISO protein:decreased expression:esophagus (human) RGD PMID:30464518 RGD:151665168 NCBI chr 1:261,732,280...261,859,833
Ensembl chr 1:261,659,660...261,859,022
JBrowse link
G DCC DCC netrin 1 receptor ISO OMIM NCBI chr 1:101,518,629...103,087,021
Ensembl chr 1:101,846,100...103,083,096
JBrowse link
G DIDO1 death inducer-obliterator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chr17:62,126,026...62,174,095
Ensembl chr17:62,125,122...62,174,071
JBrowse link
G DNMT3B DNA methyltransferase 3 beta disease_progression ISO protein:increased expression:nucleus: RGD PMID:22213175 RGD:9589085 NCBI chr17:36,345,715...36,386,076
Ensembl chr17:36,345,816...36,386,072
JBrowse link
G DPP4 dipeptidyl peptidase 4 ISO protein:increased expression: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr15:68,661,764...68,742,961
Ensembl chr15:68,660,521...68,743,663
JBrowse link
G EFNB2 ephrin B2 ameliorates
severity
exacerbates
ISO human cells in mouse model
mRNA:increased expression:esophagus squamous epithelium (human)
mRNA,protein:increased expression:esophagus squamous epithelium (human)
RGD PMID:17611172 PMID:29190834 PMID:31885720 RGD:153300947 RGD:153300948 RGD:153300949 NCBI chr11:74,188,337...74,232,768
Ensembl chr11:74,186,640...74,233,354
JBrowse link
G EGFR epidermal growth factor receptor severity ISO protein:increased expression:esophagus (human)
ClinVar Annotator: match by term: Esophageal squamous cell carcinoma
RGD
ClinVar
PMID:10385363 PMID:23485129 PMID:25157968 RGD:5131486 NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589
JBrowse link
G EHMT1 euchromatic histone lysine methyltransferase 1 disease_progression ISO protein:increased expression:esophagus mucosa:
protein:increased expression:esophagus:
RGD PMID:24649311 PMID:24805087 RGD:9589143 RGD:9590071
G EHMT2 euchromatic histone lysine methyltransferase 2 disease_progression ISO protein:increased expression:esophagus mucosa: RGD PMID:24805087 RGD:9590071 NCBI chr 7:23,977,683...23,992,673
Ensembl chr 7:23,977,683...23,993,478
JBrowse link
G EP300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17965222 PMID:25151357 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760
JBrowse link
G EPB41L3 erythrocyte membrane protein band 4.1 like 3 disease_progression ISO DNA:hypermethylation RGD PMID:25050929 RGD:151665741 NCBI chr 6:101,420,376...101,671,177
Ensembl chr 6:101,420,396...101,671,169
JBrowse link
G EPHB4 EPH receptor B4 exacerbates ISO mRNA,protein:increased expression:esophagus squamous epithelium (human) RGD PMID:31885720 RGD:153300949 NCBI chr 3:8,671,052...8,689,778
Ensembl chr 3:8,668,859...8,689,783
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 susceptibility
disease_progression
ISO DNA:SNPs, haplotypes: :rs1595066 and rs16845990 (human)
protein:altered localization:nucleus
RGD PMID:18000820 PMID:24916311 RGD:126781764 RGD:126781765 NCBI chr15:113,966,573...115,096,984
Ensembl chr15:113,974,437...115,096,565
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment ISO RGD PMID:23263828 RGD:11252162 NCBI chr 6:51,783,537...51,808,898
Ensembl chr 6:51,783,478...51,798,984
JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression ISO RGD PMID:21165554 PMID:25613619 RGD:126781697 RGD:126781701 NCBI chr 9:109,384,976...109,450,943
Ensembl chr 9:109,385,015...109,450,941
JBrowse link
G FANCA FA complementation group A ISO DNA:missense mutation: :p.S858R (human) RGD PMID:21279724 RGD:11344913 NCBI chr 6:253,207...300,159
Ensembl chr 6:253,207...300,152
JBrowse link
G FAP fibroblast activation protein alpha ISO protein:increased expression: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr15:68,831,281...68,902,416
Ensembl chr15:68,830,730...68,902,379
JBrowse link
G FASN fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr12:922,405...937,560
Ensembl chr12:920,509...937,561
JBrowse link
G FAT1 FAT atypical cadherin 1 ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:esophagus squamous epithelium (human)
CTD
RGD
PMID:24590895 PMID:25151357 PMID:29365412 RGD:151347630 RGD:151347646 NCBI chr17:8,466,099...8,580,715
Ensembl chr17:8,457,187...8,580,715
JBrowse link
G FAT2 FAT atypical cadherin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr16:71,448,491...71,531,664
Ensembl chr16:71,469,847...71,530,501
JBrowse link
G FAT3 FAT atypical cadherin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 9:24,772,394...25,476,424 JBrowse link
G FAT4 FAT atypical cadherin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 8:99,141,967...99,312,131
Ensembl chr 8:99,148,496...99,310,519
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 8:76,482,027...76,699,354
Ensembl chr 8:76,482,844...76,699,348
JBrowse link
G FES FES proto-oncogene, tyrosine kinase exacerbates ISO DNA:hypermethylation: (human) RGD PMID:24936140 RGD:153323298 NCBI chr 7:53,472,947...53,485,084
Ensembl chr 7:53,472,947...53,485,082
JBrowse link
G FGFR4 fibroblast growth factor receptor 4 treatment ISO RGD PMID:25989802 RGD:150520041 NCBI chr 2:80,841,536...80,853,791
Ensembl chr 2:80,841,536...80,853,796
JBrowse link
G FKBP1A FKBP prolyl isomerase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr17:33,910,047...33,935,212 JBrowse link
G FOXA1 forkhead box A1 onset ISO DNA:SNPs: :rs12894364 C>T, rs2145146 C>A (human) RGD PMID:27050876 PMID:29788741 RGD:151665743 RGD:151665759 NCBI chr 7:62,471,233...62,479,638
Ensembl chr 7:62,471,249...62,479,220
JBrowse link
G FUBP1 far upstream element binding protein 1 exacerbates ISO mRNA:increased expression:esophagus (human)
protein:increased expression:esophagus (human)
RGD PMID:26490982 PMID:32481602 RGD:151361192 RGD:151361197 NCBI chr 6:135,281,474...135,319,055
Ensembl chr 6:135,281,521...135,318,714
JBrowse link
G GDI2 GDP dissociation inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr10:65,160,700...65,196,447
Ensembl chr10:65,160,653...65,196,447
JBrowse link
G GLO1 glyoxalase I ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 7:34,156,194...34,183,560
Ensembl chr 7:34,157,535...34,183,528
JBrowse link
G GPX3 glutathione peroxidase 3 disease_progression ISO DNA:hypermethylation RGD PMID:25050929 PMID:30018730 RGD:151665494 RGD:151665741 NCBI chr16:71,980,467...71,989,011
Ensembl chr16:71,980,475...71,989,026
JBrowse link
G GRB7 growth factor receptor bound protein 7 exacerbates ISO protein:increased expression:esophagus (human)
mRNA:increased expression:esophagus mucosa (human)
RGD PMID:10797316 PMID:26465158 RGD:151347654 RGD:151347661 NCBI chr12:22,574,579...22,583,386
Ensembl chr12:22,574,584...22,582,345
JBrowse link
G GSTO1 glutathione S-transferase omega 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr14:115,206,434...115,216,624
Ensembl chr14:115,206,188...115,216,613
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:17201171 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845
JBrowse link
G HMGB1 high mobility group box 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr11:7,195,556...7,321,071 JBrowse link
G HMGN5 high mobility group nucleosome binding domain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28914995 NCBI chr  X:64,541,310...64,617,345 JBrowse link
G HOXB7 homeobox B7 severity ISO protein:increased expression:esophageal mucosa (human) RGD PMID:26076456 RGD:10402177 NCBI chr12:24,861,165...24,864,675
Ensembl chr12:24,861,174...24,864,620
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894
JBrowse link
G HTRA1 HtrA serine peptidase 1 ameliorates
exacerbates
ISO human gene and cells in mouse model
mRNA,protein:decreased expression:epithelium of esophagus (human)
RGD PMID:23079781 RGD:152975633 NCBI chr14:132,043,044...132,103,590
Ensembl chr14:132,041,934...132,103,595
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO human cells in mouse model RGD PMID:32367071 RGD:149735568 NCBI chr 7:55,654,298...55,675,571
Ensembl chr 7:55,651,609...55,675,554
JBrowse link
G JAK2 Janus kinase 2 severity ISO protein:increased phosphorylation:esophagus squamous epithelium (human) RGD PMID:32158193 RGD:127285669 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit exacerbates ISO protein:increased expression:esophagus (human) RGD PMID:19758438 PMID:30227324 RGD:151347669 RGD:151347672 NCBI chr 2:66,214,086...66,219,435
Ensembl chr 2:66,214,138...66,217,002
JBrowse link
G KAT2B lysine acetyltransferase 2B ISO mRNA:decreased expression:esophagus (human) RGD PMID:19525977 RGD:9590307 NCBI chr13:6,985,151...7,099,771
Ensembl chr13:6,985,235...7,100,345
JBrowse link
G KDM4C lysine demethylase 4C susceptibility
severity
ISO DNA:snp:intron:IVS8-3292G>A (rs1340513) (human)
protein:increased expression:esophageal epithelium, nucleus (human)
RGD PMID:15805246 PMID:24224128 RGD:9587746 RGD:9587752 NCBI chr 1:215,071,335...215,507,778
Ensembl chr 1:215,071,419...215,507,800
JBrowse link
G KDM5B lysine demethylase 5B severity ISO protein:increased expression:esophageal mucosa, cytoplasm (human) RGD PMID:22534467 RGD:9587776 NCBI chr10:24,739,115...24,831,537
Ensembl chr10:24,736,838...24,831,447
JBrowse link
G KDM6A lysine demethylase 6A ameliorates ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:esophagus (human)
protein:increased expression:esophagus (human)
DNA:mutations:multiple (human)
CTD
RGD
PMID:25151357 PMID:29351209 PMID:31804468 RGD:150429739 RGD:150429742 RGD:9588233 NCBI chr  X:39,953,764...40,154,197
Ensembl chr  X:39,953,814...40,154,029
JBrowse link
G KMT2C lysine methyltransferase 2C ISO CTD Direct Evidence: marker/mechanism
DNA:mutations:multiple (human)
CTD
RGD
PMID:25151357 RGD:9588233 NCBI chr18:4,993,213...5,279,668
Ensembl chr18:4,993,227...5,278,723
JBrowse link
G KMT2D lysine methyltransferase 2D ISO DNA:mutations:multiple (human)
mRNA:increased expression:esophagus
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:25151357 PMID:29532228 RGD:150521712 RGD:9588233 NCBI chr 5:15,049,827...15,091,622 JBrowse link
G KRT19 keratin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr12:21,115,453...21,119,115
Ensembl chr12:21,115,448...21,119,107
JBrowse link
G KRT7 keratin 7 disease_progression ISO RGD PMID:29788741 RGD:151665759 NCBI chr 5:17,553,192...17,570,582
Ensembl chr 5:17,555,728...17,570,581
JBrowse link
G LOC100515166 keratin, type I cytoskeletal 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr12:21,139,296...21,143,556 JBrowse link
G LOC100737030 keratin, type I cytoskeletal 42 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr12:21,014,182...21,022,123 JBrowse link
G LOC100739508 glutathione S-transferase P-like ISO DNA:polymorphism: :p.I105V (human) RGD PMID:17916905 RGD:14700982 NCBI chr 2:5,005,498...5,009,247 JBrowse link
G LOC110255312 keratin, type I cytoskeletal 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16543248 NCBI chr12:21,074,965...21,079,393
Ensembl chr12:21,024,314...21,119,396
JBrowse link
G LOXL2 lysyl oxidase like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24716982 NCBI chr14:7,435,861...7,540,699
Ensembl chr14:7,435,867...7,540,704
JBrowse link
G LTA lymphotoxin alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr 7:23,696,387...23,698,280
Ensembl chr 7:23,696,040...23,698,299
JBrowse link
G LZTS1 leucine zipper tumor suppressor 1 ISO ClinVar Annotator: match by term: Esophageal squamous cell carcinoma, somatic | ClinVar Annotator: match by term: LZTS1-related condition OMIM
ClinVar
PMID:10097140 PMID:25741868 PMID:26504261 PMID:28492532 NCBI chr14:4,344,496...4,404,208
Ensembl chr14:4,346,480...4,404,168
JBrowse link
G MAD2L1 mitotic arrest deficient 2 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18691855 NCBI chr 8:103,927,358...103,936,669
Ensembl chr 8:103,927,353...103,936,664
JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 sexual_dimorphism ISO DNA:missense mutation, SNP:CDS, exon 14, 3'-UTR: (rs702689,rs702688) (human) RGD PMID:32753933 RGD:150573717 NCBI chr16:35,872,301...35,947,097
Ensembl chr16:35,872,131...35,946,987
JBrowse link
G MBD4 methyl-CpG binding domain 4, DNA glycosylase susceptibility ISO DNA:snp:intron:IVS5-140A>G (rs3138355) (human)
DNA:snp:cds:p.E346K (rs140693) (human)
RGD PMID:15205355 PMID:25162968 RGD:9588976 RGD:9588980 NCBI chr13:68,816,677...68,828,559
Ensembl chr13:68,816,679...68,828,580
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase disease_progression ISO CTD Direct Evidence: marker/mechanism
DNA, protein:hypermethylation, decreased expression:promoter, esophagus
CTD
RGD
PMID:21674174 PMID:25520135 RGD:126790574 NCBI chr14:138,502,005...138,771,543
Ensembl chr14:138,499,309...138,771,540
JBrowse link
G MIR10A microRNA mir-10a ISO miRNA:increased expression:esophagus squamous epithelium (human) RGD PMID:32997362 RGD:153323343 NCBI chr12:24,833,644...24,833,723
Ensembl chr12:24,833,627...24,833,730
JBrowse link
G MIR127 microRNA mir-127 ISO RNA:decreased expression:esophagus (human) RGD PMID:27645894 RGD:152995354 NCBI chr 7:121,709,636...121,709,715
Ensembl chr 7:121,709,640...121,709,720
JBrowse link
G MIR193A microRNA mir-193a exacerbates ISO miRNA:decreased expression:esophagus (human) RGD PMID:27203740 RGD:153323341 NCBI chr12:43,336,969...43,337,048
Ensembl chr12:43,336,969...43,337,048
JBrowse link
G MIR217-1 microRNA mir-217-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25538231 NCBI chr 3:85,341,255...85,341,361
Ensembl chr 3:85,341,255...85,341,361
JBrowse link
G MIR31 microRNA mir-31 ameliorates ISO RGD PMID:21658006 PMID:32123074 RGD:127285381 RGD:152998938 NCBI chr 1:201,198,732...201,198,809
Ensembl chr 1:201,198,732...201,198,809
JBrowse link
G MIR423 microRNA mir-423 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24205249 NCBI chr12:46,211,525...46,211,604
Ensembl chr12:46,211,525...46,211,611
JBrowse link
G MIR432 microRNA mir-432 ISO mRNA:increased expression:esophagus (human) RGD PMID:28760781 RGD:153002560 NCBI chr 7:121,711,137...121,711,216
Ensembl chr 7:121,711,137...121,711,216
JBrowse link
G MLH1 mutL homolog 1 disease_progression ISO DNA, protein:hypermethylation, decreased expression:promoter, esophagus RGD PMID:21674174 RGD:126790574 NCBI chr13:21,791,276...21,877,789
Ensembl chr13:21,791,203...21,877,757
JBrowse link
G MMP14 matrix metallopeptidase 14 ISO protein:increased expression: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr 7:76,174,502...76,185,931
Ensembl chr 7:76,172,971...76,185,928
JBrowse link
G MMP2 matrix metallopeptidase 2 ISO protein:increased activity: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO protein:increased activity: esophagus RGD PMID:24789592 RGD:152600903 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788
JBrowse link
G MSH2 mutS homolog 2 disease_progression ISO DNA, protein:hypermethylation, decreased expression:promoter, esophagus
DNA, protein:hypermethylation, decreased expression:esophagus
RGD PMID:21674174 PMID:22265839 PMID:24366688 RGD:126790560 RGD:126790573 RGD:126790574 NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,585
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183
JBrowse link
G NOTCH1 notch receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357
G NOTCH2 notch receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 4:100,951,522...101,152,348
Ensembl chr 4:100,981,636...101,150,195
JBrowse link
G NOTCH3 notch receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr 2:62,364,507...62,402,348
Ensembl chr 2:62,364,501...62,402,344
JBrowse link
G PAGR1 PAXIP1 associated glutamate rich protein 1 ISO mRNA, protein:decreased expression:esophagus (human) RGD PMID:33833989 RGD:153344568 NCBI chr 3:18,052,679...18,056,920
Ensembl chr 3:18,052,935...18,056,837
JBrowse link
G PBX3 PBX homeobox 3 ISO RNA:increased expression:esophagus squamous epithelium (human) RGD PMID:32449803 RGD:153345544 NCBI chr 1:266,383,311...266,610,646
Ensembl chr 1:266,382,640...266,610,640
JBrowse link
G PFN1 profilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr12:51,962,642...51,965,570
Ensembl chr12:51,961,952...51,965,464
JBrowse link
G PLCE1 phospholipase C epsilon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20729852 PMID:20729853 NCBI chr14:105,422,628...105,764,736
Ensembl chr14:105,458,916...105,764,737
JBrowse link
G PRDX1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 6:165,847,390...165,859,918
Ensembl chr 6:165,824,395...165,861,442
JBrowse link
G PSMB9 proteasome 20S subunit beta 9 disease_progression ISO RGD PMID:19492245 RGD:6482249 NCBI chr 7:25,072,133...25,077,508
Ensembl chr 7:25,062,367...25,077,523
JBrowse link
G PSME1 proteasome activator subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 7:75,161,830...75,164,531
Ensembl chr 7:75,160,766...75,164,810
JBrowse link
G PSME2 proteasome activator subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 7:75,154,570...75,157,871
Ensembl chr 7:75,153,965...75,157,870
JBrowse link
G PTCH1 patched 1 disease_progression ISO RGD PMID:16475698 RGD:150523841 NCBI chr10:26,627,165...26,703,225
Ensembl chr10:26,627,425...26,703,223
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15756444 PMID:16543248 PMID:18197933 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884
JBrowse link
G PTPRT protein tyrosine phosphatase receptor type T susceptibility ISO DNA:SNPs:3'utr: (rs2866943 , rs6029959 ) (human) RGD PMID:25967969 RGD:150520191 NCBI chr17:44,717,539...45,880,822
Ensembl chr17:44,714,645...45,881,041
JBrowse link
G RB1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25151357 NCBI chr11:19,186,754...19,317,642
Ensembl chr11:19,186,761...19,317,690
JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 severity
disease_progression
ISO protein:increased expression:esophagus (human)
human cells in mouse model
RGD PMID:28132115 PMID:30119206 PMID:32642408 RGD:152995460 RGD:152995470 RGD:152995512 NCBI chr16:24,109,934...24,250,019
Ensembl chr16:24,109,939...24,311,132
JBrowse link
G RNF6 ring finger protein 6 ISO ClinVar Annotator: match by term: Esophageal squamous cell carcinoma, somatic ClinVar
OMIM
PMID:12154016 NCBI chr11:4,020,752...4,033,040
Ensembl chr11:4,020,852...4,031,787
JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO DNA:SNP: :rs2014300 (human) RGD PMID:30666517 RGD:126775149 NCBI chr13:198,371,835...198,635,648
Ensembl chr13:198,371,837...198,638,189
JBrowse link
G RUNX2 RUNX family transcription factor 2 ISO mRNA:increased expression:esophagus mucosa RGD PMID:18500170 RGD:126779568 NCBI chr 7:40,106,581...40,353,304
Ensembl chr 7:40,106,532...40,460,687
JBrowse link
G RUNX3 RUNX family transcription factor 3 disease_progression ISO mRNA:decreased expression:esophagus mucosa RGD PMID:18500170 RGD:126779568 NCBI chr 6:82,531,203...82,595,044
Ensembl chr 6:82,531,559...82,595,026
JBrowse link
G SALL4 spalt like transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chr17:53,082,610...53,103,023
Ensembl chr17:53,084,310...53,103,190
JBrowse link
G SETD5 SET domain containing 5 disease_progression ISO RGD PMID:31981592 RGD:155804254 NCBI chr13:65,759,973...65,851,747
Ensembl chr13:65,759,987...65,850,506
JBrowse link
G SFN stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 6:84,188,521...84,189,824
Ensembl chr 6:84,188,445...84,189,827
JBrowse link
G SLC16A10 solute carrier family 16 member 10 ISO protein:increased expression:esophagus RGD PMID:33609949 RGD:151361149 NCBI chr 1:76,998,359...77,139,534
Ensembl chr 1:76,998,359...77,138,639
JBrowse link
G SLC1A5 solute carrier family 1 member 5 disease_progression ISO protein:increased expression:esophagus RGD PMID:26936531 PMID:33609949 RGD:11532833 RGD:151361149 NCBI chr 6:52,647,432...52,661,464
Ensembl chr 6:52,647,438...52,661,459
JBrowse link
G SLC39A6 solute carrier family 39 member 6 ISO CTD Direct Evidence: therapeutic CTD PMID:23644492 NCBI chr 6:119,861,853...119,885,836
Ensembl chr 6:119,861,846...119,885,378
JBrowse link
G SLC52A3 solute carrier family 52 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20729853 NCBI chr17:34,459,291...34,481,022
Ensembl chr17:34,459,359...34,481,026
JBrowse link
G SLC7A5 solute carrier family 7 member 5 disease_progression ISO protein:increased expression:esophagus RGD PMID:26936531 PMID:31726270 PMID:33609949 RGD:11532833 RGD:151361144 RGD:151361149 NCBI chr 6:1,545,940...1,574,298
Ensembl chr 6:1,545,944...1,574,285
JBrowse link
G SOCS1 suppressor of cytokine signaling 1 severity
treatment
ISO mRNA:decreased expression:esophagus RGD PMID:21385099 PMID:28233302 PMID:31728180 RGD:150573691 RGD:150573812 RGD:150573815 NCBI chr 3:31,879,143...31,883,041
Ensembl chr 3:31,881,225...31,884,967
JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18167182 PMID:21517111 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560
JBrowse link
G SOX2 SRY-box transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19801978 NCBI chr13:119,668,476...119,669,435
Ensembl chr13:119,668,476...119,669,435
JBrowse link
G SPEN spen family transcriptional repressor ISO associated with Neoplasm Metastasis; DNA:mutations RGD PMID:33363385 RGD:151347445 NCBI chr 6:75,015,565...75,107,468
Ensembl chr 6:75,015,521...75,107,033
JBrowse link
G STIM1 stromal interaction molecule 1 exacerbates ISO protein:increased expression:esophagus (human) RGD PMID:31843504 RGD:152995393 NCBI chr 9:6,066,612...6,270,090
Ensembl chr 9:6,066,617...6,270,575
JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25129146 NCBI chr 2:141,359,402...141,367,222
Ensembl chr 2:141,358,993...141,367,198
JBrowse link
G TAGLN transgelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 9:44,561,756...44,567,385
Ensembl chr 9:44,560,785...44,567,385
JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member ISO protein:decreased expression:esophagus RGD PMID:19492245 RGD:6482249 NCBI chr 7:25,062,772...25,071,989
Ensembl chr 7:25,062,771...25,074,843
JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member ISO protein:decreased expression:esophagus RGD PMID:19492245 RGD:6482249 NCBI chr 7:25,045,085...25,056,915
Ensembl chr 7:25,045,685...25,056,300
JBrowse link
G TCN2 transcobalamin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr14:47,496,245...47,515,966
Ensembl chr14:47,502,715...47,515,965
JBrowse link
G TERT telomerase reverse transcriptase susceptibility
no_association
ISO DNA:SNPs: : rs2853691,rs2736100(human)
mRNA:increased expression:esophagus squamous epithelium:
DNA:SNP: :rs2736098(human)
RGD PMID:15112252 PMID:25007268 PMID:26716642 RGD:11572962 RGD:150530488 RGD:152977757 NCBI chr16:79,258,591...79,276,421
Ensembl chr16:79,258,591...79,276,421
JBrowse link
G TET2 tet methylcytosine dioxygenase 2 severity ISO DNA:mutations
mRNA:decreased expression:esophagus squamous epithelium (human)
associated with Lymphatic Metastasis;mRNA:decreased expression:esophagus squamous epithelium (human)
RGD PMID:26093090 PMID:26873401 PMID:27050164 RGD:11528815 RGD:150429656 RGD:150429668 NCBI chr 8:116,413,253...116,546,976
Ensembl chr 8:116,415,267...116,545,299
JBrowse link
G TET3 tet methylcytosine dioxygenase 3 ISO mRNA:decreased expression:esophagus squamous epithelium (human) RGD PMID:27050164 RGD:150429668 NCBI chr 3:68,918,896...69,020,406
Ensembl chr 3:68,918,933...69,020,986
JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO OMIM NCBI chr13:16,784,370...16,875,828
Ensembl chr13:16,784,490...16,878,160
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 severity ISO mRNA,protein:increased expression:esophagus squamous epithelium (human) RGD PMID:28197630 RGD:151347617 NCBI chr 1:26,474,158...26,489,771
Ensembl chr 1:26,473,938...26,489,822
JBrowse link
G TNFAIP8 TNF alpha induced protein 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21969086 NCBI chr 2:123,152,349...123,285,154
Ensembl chr 2:123,152,371...123,287,941
JBrowse link
G TNXB tenascin XB ISO CTD Direct Evidence: marker/mechanism CTD PMID:29379198 NCBI chr 7:24,088,873...24,155,815
Ensembl chr 7:24,088,873...24,150,596
JBrowse link
G TP53 tumor protein p53 ISO DNA:misssense mutation: :p.R72P (rs1042522) (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16543248 PMID:25151357 PMID:28789369 RGD:14995932 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
G TPI1 triosephosphate isomerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 5:63,839,473...63,842,853
Ensembl chr 5:63,838,506...63,843,134
JBrowse link
G TPM1 tropomyosin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 1:108,986,981...109,016,090
Ensembl chr 1:108,986,986...109,020,035
JBrowse link
G TPM2 tropomyosin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr 1:236,402,249...236,410,390
Ensembl chr 1:236,402,251...236,410,905
JBrowse link
G TXNDC17 thioredoxin domain containing 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21517111 NCBI chr12:50,734,669...50,737,309
Ensembl chr12:50,734,619...50,737,078
JBrowse link
G USP8 ubiquitin specific peptidase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35022897 NCBI chr 1:121,306,031...121,376,154
Ensembl chr 1:121,306,032...121,413,223
JBrowse link
G VENTX VENT homeobox ISO CTD Direct Evidence: marker/mechanism CTD PMID:30431698 NCBI chr14:141,265,966...141,271,379 JBrowse link
G WRAP53 WD repeat containing antisense to TP53 disease_progression ISO RGD PMID:24626331 RGD:21081532 NCBI chr12:52,954,674...52,968,371
Ensembl chr12:52,954,669...52,968,364
JBrowse link
G WWOX WW domain containing oxidoreductase ISO ClinVar Annotator: match by term: Esophageal squamous cell carcinoma, somatic ClinVar
OMIM
PMID:11956080 PMID:28492532 NCBI chr 6:8,910,209...9,871,048
Ensembl chr 6:8,910,138...9,871,053
JBrowse link
G XPO1 exportin 1 exacerbates ISO mRNA, protein:increased expression:epithelium of esophagus (human)
protein:increased expression:esophagus (human)
RGD PMID:24898882 PMID:25148895 RGD:151667431 RGD:151667436 NCBI chr 3:80,255,016...80,300,260
Ensembl chr 3:80,255,146...80,300,327
JBrowse link
G XRCC1 X-ray repair cross complementing 1 no_association
susceptibility
treatment
ISO CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds: p.R399Q (human)
DNA:SNPs,haplotypes:multiple (human)
DNA:SNPs:exon 6, exon 9, exon 10:multiple (human)
CTD
RGD
PMID:11400117 PMID:16639733 PMID:25710005 PMID:27123143 PMID:28356949 RGD:150530501 RGD:150530505 RGD:150530634 RGD:151347444 NCBI chr 6:50,403,691...50,425,730
Ensembl chr 6:50,403,689...50,425,729
JBrowse link
Familial Cystic Parathyroid Adenomatosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC73 cell division cycle 73 ISO ClinVar Annotator: match by term: Cystic parathyroid adenoma ClinVar PMID:12434154 NCBI chr10:575,075...667,618
Ensembl chr10:575,075...667,432
JBrowse link
familial medullary thyroid carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INSRR insulin receptor related receptor ISO ClinVar Annotator: match by term: Familial medullary thyroid carcinoma | ClinVar Annotator: match by term: Thyroid cancer, familial medullary ClinVar NCBI chr 4:93,239,678...93,258,075
Ensembl chr 4:93,239,969...93,258,075
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 ISO ClinVar Annotator: match by term: Familial medullary thyroid carcinoma | ClinVar Annotator: match by term: Thyroid cancer, familial medullary ClinVar PMID:10330344 PMID:10443680 PMID:10861667 PMID:11139246 PMID:11159935 More... NCBI chr 4:93,219,509...93,237,944
Ensembl chr 4:93,219,516...93,255,981
JBrowse link
G PRLR prolactin receptor ISO OMIM:155240 MouseDO NCBI chr16:20,637,568...20,655,881
Ensembl chr16:20,618,875...20,810,140
JBrowse link
G RET ret proto-oncogene ISO ClinVar Annotator: match by term: Familial medullary thyroid carcinoma | ClinVar Annotator: match by term: Thyroid cancer, familial medullary OMIM
ClinVar
PMID:2660074 PMID:3078962 PMID:3697657 PMID:7536460 PMID:7595170 More... NCBI chr14:61,305,818...61,361,416
Ensembl chr14:61,305,841...61,361,412
JBrowse link
Follicular Thyroid Cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 ClinVar PMID:12068308 PMID:12198537 PMID:12960123 PMID:14679157 PMID:15035987 More... NCBI chr18:8,957,963...9,132,558
Ensembl chr18:8,957,991...9,132,553
JBrowse link
G CBX7 chromobox 7 ISO protein:decreased expression:thyroid gland: RGD PMID:18701502 RGD:9587357 NCBI chr 5:9,070,312...9,090,467
Ensembl chr 5:9,070,353...9,087,634
JBrowse link
G CGA glycoprotein hormones, alpha polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:10566621 NCBI chr 1:55,552,675...55,569,057
Ensembl chr 1:55,551,320...55,568,991
JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: THYROID CANCER, NONMEDULLARY, 2 | ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 OMIM
ClinVar
PMID:12727991 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 More... NCBI chr 2:299,662...302,539
Ensembl chr 2:299,660...302,501
JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: THYROID CANCER, NONMEDULLARY, 2 | ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 ClinVar PMID:12727991 PMID:16170316 PMID:16329078 PMID:16372351 PMID:16443854 More... NCBI chr 2:303,836...323,701
Ensembl chr 2:304,430...323,699
JBrowse link
G MINPP1 multiple inositol-polyphosphate phosphatase 1 ISO ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 OMIM
ClinVar
PMID:11297621 NCBI chr14:99,574,426...99,628,388
Ensembl chr14:99,574,440...99,628,173
JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 OMIM
ClinVar
PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr 4:105,845,913...105,853,769
Ensembl chr 4:105,845,872...105,858,227
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:15785241 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944
JBrowse link
G PTEN phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 ClinVar NCBI chr14:99,929,590...100,021,619 JBrowse link
G SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 ISO ClinVar Annotator: match by term: Thyroid cancer, nonmedullary, 2 OMIM
ClinVar
PMID:23539728 PMID:25741868 PMID:28492532 NCBI chr 5:28,300,955...28,605,122
Ensembl chr 5:28,300,950...28,605,120
JBrowse link
glottis squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WRAP53 WD repeat containing antisense to TP53 disease_progression ISO RGD PMID:28849066 RGD:21081521 NCBI chr12:52,954,674...52,968,371
Ensembl chr12:52,954,669...52,968,364
JBrowse link
head and neck cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNG1 cyclin G1 ISO mRNA:decreased expression:head and neck (human) RGD PMID:27982046 RGD:151361200 NCBI chr16:60,349,255...60,356,737
Ensembl chr16:60,349,258...60,356,738
JBrowse link
G CCNG2 cyclin G2 ISO mRNA:decreased expression:head and neck (human) RGD PMID:27982046 RGD:151361200 NCBI chr 8:72,790,394...72,800,553
Ensembl chr 8:72,791,703...72,800,551
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 exacerbates ISO mRNA:increased expression:head, neck (human) RGD PMID:31452775 RGD:150520018 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO DNA:hypermethylation RGD PMID:16721740 PMID:20846153 RGD:14700957 RGD:14700978 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775
JBrowse link
G EGFR epidermal growth factor receptor ISO ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:18089823 PMID:18355544 PMID:21172876 PMID:21274259 PMID:23380224 More... NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589
JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:7668257 PMID:7719344 PMID:8651276 PMID:9677057 PMID:9700203 More... NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425
JBrowse link
G KDM4C lysine demethylase 4C susceptibility ISO DNA:snps:cds, intron:p.N396D (rs2296067), IVS10G>T (rs818912) (human) RGD PMID:19339270 RGD:9587748 NCBI chr 1:215,071,335...215,507,778
Ensembl chr 1:215,071,419...215,507,800
JBrowse link
G LOC100517025 uncharacterized LOC100517025 ISO ClinVar Annotator: match by term: Head and neck cancer ClinVar PMID:28492532 PMID:32266149 NCBI chr 2:29,365,181...29,796,389
Ensembl chr 2:29,365,195...29,792,979
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:15016963 PMID:15254419 PMID:15647370 PMID:15805248 PMID:16906227 More... NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,274,587
JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein ISO ClinVar Annotator: match by term: Head and neck cancer ClinVar PMID:32266149 NCBI chr12:51,772,635...51,794,107
Ensembl chr12:51,773,448...51,794,104
JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Head and neck neoplasm ClinVar PMID:9067756 PMID:11370630 PMID:11782540 PMID:16818505 PMID:17606709 More... NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818
JBrowse link
head and neck squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr 9:93,049,955...93,146,469 JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr 3:28,360,868...28,472,940
Ensembl chr 3:28,360,873...28,473,456
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr14:110,955,698...111,038,898
Ensembl chr14:110,955,633...111,037,537
JBrowse link
G ABCG2A ATP binding cassette subfamily G member 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25275603 NCBI chr 8:130,853,414...130,945,388
Ensembl chr 8:130,889,684...130,945,393
JBrowse link
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:11569495 PMID:11853795 PMID:12399961 PMID:12623848 PMID:14745431 More... NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,708
JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Head and neck squamous cell carcinoma ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More...
G ANKRD17 ankyrin repeat domain 17 ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:28580594 NCBI chr 8:69,360,641...69,531,418
Ensembl chr 8:69,360,649...69,531,286
JBrowse link
G ATP7B ATPase copper transporting beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:12509969 NCBI chr11:15,892,549...15,942,070
Ensembl chr11:15,876,612...15,942,064
JBrowse link
G B2M beta-2-microglobulin ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:26619011 NCBI chr 1:126,837,721...126,844,043
Ensembl chr 1:126,835,143...126,981,582
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 ameliorates ISO mRNA:increased expression:head or neck skin (human) RGD PMID:31964418 RGD:153344516 NCBI chr 9:33,003,570...33,020,252
Ensembl chr 9:33,003,276...33,020,242
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma | ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... NCBI chr18:8,957,963...9,132,558
Ensembl chr18:8,957,991...9,132,553
JBrowse link
G CASP8 caspase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23358896 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
JBrowse link
G CCNA1 cyclin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23358896 PMID:29464035 NCBI chr11:12,396,149...12,405,357
Ensembl chr11:12,396,301...12,405,350
JBrowse link
G CCNA2 cyclin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr 8:102,260,346...102,266,274
Ensembl chr 8:102,260,215...102,266,309
JBrowse link
G CCNB1 cyclin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377
JBrowse link
G CCND1 cyclin D1 disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:9796972 PMID:26909611 PMID:29464035 RGD:13434911 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296
JBrowse link
G CCNE1 cyclin E1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr 6:39,919,541...39,933,224
Ensembl chr 6:39,919,624...39,933,363
JBrowse link
G CCNE2 cyclin E2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr 4:41,802,090...41,821,870
Ensembl chr 4:41,804,377...41,821,874
JBrowse link
G CDC73 cell division cycle 73 exacerbates ISO protein:increased expression:squamous epithelium (human) RGD PMID:26124004 RGD:11065919 NCBI chr10:575,075...667,618
Ensembl chr10:575,075...667,432
JBrowse link
G CDK2 cyclin dependent kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr 5:21,365,723...21,372,170
Ensembl chr 5:21,365,764...21,372,168
JBrowse link
G CDK4 cyclin dependent kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr 5:23,039,206...23,041,959
Ensembl chr 5:23,038,891...23,042,061
JBrowse link
G CDK6 cyclin dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29464035 NCBI chr 9:72,510,858...72,765,631
Ensembl chr 9:72,518,101...72,764,129
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A disease_progression ISO DNA:SNPs: :rs3731217, rs3088440 (human)
ClinVar Annotator: match by term: Head and neck squamous cell carcinoma | ClinVar Annotator: match by term: Lip and oral cavity carcinoma | ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck
RGD
ClinVar
PMID:7718873 PMID:7777061 PMID:7780957 PMID:8153634 PMID:8521414 More... RGD:8552291 NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854
JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 ISO mRNA:increased expression:head or neck skin (human) RGD PMID:28486105 RGD:153323299 NCBI chr 5:64,071,627...64,105,212
Ensembl chr 5:64,065,992...64,105,173
JBrowse link
G CLDN1 claudin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33665778 NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657
JBrowse link
G CNTN4 contactin 4 ISO ClinVar Annotator: match by term: Lip and oral cavity carcinoma ClinVar PMID:28595731 NCBI chr13:58,642,653...59,642,134
Ensembl chr13:58,974,198...59,642,130
JBrowse link
G CREBBP CREB binding protein ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 More... NCBI chr 3:38,388,366...38,530,243
Ensembl chr 3:38,388,547...38,530,224
JBrowse link
G CTNNB1 catenin beta 1 ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:9927029 PMID:10192393 PMID:23265383 PMID:25157968 PMID:26619011 More... NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311
JBrowse link
G CYP2C49 cytochrome P450 2C49 treatment ISO DNA:polymorphisms: :CYP2C19*2(human) RGD PMID:19954746 RGD:401901267 NCBI chr14:106,571,803...106,612,082
Ensembl chr14:106,285,173...106,612,455
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 treatment ISO DNA:polymorphisms: :CYP2D6*4,CYP2D6*10(human) RGD PMID:19954746 RGD:401901267 NCBI chr 5:6,539,021...6,543,643
Ensembl chr 5:6,538,907...6,543,642
JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 severity ISO RGD PMID:24556606 RGD:150429746 NCBI chr 4:87,749,738...87,911,818
Ensembl chr 4:87,756,168...87,911,296
JBrowse link
G DNMT3B DNA methyltransferase 3 beta susceptibility ISO DNA:SNP,haplotype:promoter:-149C>T,-579G>T(human) RGD PMID:18455294 RGD:9589078 NCBI chr17:36,345,715...36,386,076
Ensembl chr17:36,345,816...36,386,072
JBrowse link
G DPYD dihydropyrimidine dehydrogenase ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar NCBI chr 4:119,931,471...120,712,461
Ensembl chr 4:119,931,414...120,712,459
JBrowse link
G EGFR epidermal growth factor receptor ISO ClinVar Annotator: match by term: Head and neck squamous cell carcinoma | ClinVar Annotator: match by term: Lip and oral cavity carcinoma | ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:15118073 PMID:15118125 PMID:15788655 PMID:17177598 PMID:20415598 More... NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589
JBrowse link
G EP300 E1A binding protein p300 ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:26619011 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO ClinVar Annotator: match by term: Head and neck squamous cell carcinoma RGD
ClinVar
PMID:20604875 PMID:22908275 PMID:26619011 RGD:126790467 NCBI chr12:22,591,621...22,621,384
Ensembl chr12:22,590,725...22,621,351
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 severity ISO RGD PMID:20604875 RGD:126790467 NCBI chr15:113,966,573...115,096,984
Ensembl chr15:113,974,437...115,096,565
JBrowse link
G FANCB FA complementation group B ISO DNA:hypermethylation:promoter RGD PMID:20332657 RGD:11344903 NCBI chr  X:11,386,360...11,408,958
Ensembl chr  X:11,384,912...11,409,057
JBrowse link
G FANCD2 FA complementation group D2 ISO RGD PMID:20935219 RGD:11344907 NCBI chr13:66,241,951...66,308,601
Ensembl chr13:66,241,967...66,310,433
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:25741868 PMID:26619011 NCBI chr 8:76,482,027...76,699,354
Ensembl chr 8:76,482,844...76,699,348